3 Dee - Database of Protein Domain Definitions

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The current cluster is formed at a score of 0.410

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Classes% of representative set
undefined 40.81
Small proteins 1.47
Peptides 0.37
Membrane and cell surface proteins and peptides 1.47
Alpha and beta (a/b) 2.21
Alpha and beta (a+b) 3.68
All beta 0.74
All alpha 49.26
Breakdown into folds% of cluster % of class
undefined
undefined from 3Dee 40.81 17.45
Small proteins
Crambin-like from SCOP 0.37 0.87
Glucocorticoid receptor-like (DNA-binding domain) from SCOP 0.37 0.87
Heat-stable enterotoxin B from 3Dee 0.37 0.87
Insulin-like from SCOP 0.37 0.87
Peptides
Transmembrane helical fragments from 3Dee 0.37 2.04
Membrane and cell surface proteins and peptides
Membrane all-alpha from SCOP 0.37 9.09
Toxins' membrane translocation domains from SCOP 1.10 27.27
Alpha and beta (a/b)
ATP pyrophosphatases extra domain from 3Dee 0.37 0.36
Barstar (barnase inhibitor) from SCOP 0.37 0.36
DNA-binding winged domain from 3Dee 0.74 0.73
DNA/RNA polymerases Domain III from 3Dee 0.37 0.36
gamma,delta Resolvase, large fragment from 3Dee 0.37 0.36
Alpha and beta (a+b)
Lysozyme-like Domain I from 3Dee 0.74 1.04
Nucleotidyltransferases Domain II from 3Dee 0.37 0.52
Protein kinases (PK), catalytic core C terminal Domain from 3Dee 0.74 1.04
Ribosome inactivating proteins (RIP) Domain II from 3Dee 0.74 1.04
The intermediate domain of GroEL from 3Dee 0.37 0.52
Thymidylate synthase Extra Domain from 3Dee 0.37 0.52
Urease, gamma-subunit from SCOP 0.37 0.52
All beta
Immunoglobulin-like beta-sandwich from SCOP 0.37 0.45
Single-stranded left-handed beta-helix Domain II from 3Dee 0.37 0.45
All alpha
4-helical cytokines from SCOP 3.68 4.93
4-helical cytokines Short chain from 3Dee 0.74 0.99
Acyl-CoA binding protein from 3Dee 0.37 0.49
Acyl-CoA dehydrogenase (flavoprotein), N-terminal domain from 3Dee 0.37 0.49
Anaphylotoxins (complement system) from SCOP 0.37 0.49
Annexin Domain from 3Dee 0.74 0.99
Anticodon-binding (C-terminal) domain of glutamyl-tRNA Domain II from 3Dee 0.37 0.49
Apolipophorin-III from SCOP 0.37 0.49
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin from SCOP 1.10 1.48
Citrate synthase Domain II from 3Dee 0.74 0.99
Cytochrome c from SCOP 3.31 4.43
DNA polymerase beta, N-terminal (8 kD)-domain from 3Dee 0.37 0.49
DNA-binding 3-helical bundle from 3Dee 5.51 7.39
Diphtheria toxin repressor (DtxR) dimerization domain from 3Dee 0.37 0.49
Disulphide-bond formation facilitator (DSBA), insertion domain from SCOP 0.37 0.49
Double-stranded beta-helix, helical domain from 3Dee 0.37 0.49
EF-hand from 3Dee 2.57 3.45
Endonuclease III from 3Dee 0.74 0.99
FIS protein from 3Dee 0.37 0.49
Ferritin like from 3Dee 1.10 1.48
Four-helical up-and-down bundle from SCOP 4.41 5.91
Globin-like from SCOP 2.57 3.45
Glutathione S-transferases, C-terminal domain from SCOP 0.74 0.99
HMG-box from SCOP 0.74 0.99
Heme-linked catalases C-terminal domain from 3Dee 0.37 0.49
Hemocyanin, N-terminal domain from SCOP 0.74 0.99
Hexokinase all helical domain from 3Dee 0.37 0.49
Immunoglobulin-binding protein A, fragment B from 3Dee 0.37 0.49
Long alpha-hairpin from SCOP 1.84 2.46
Lysin from SCOP 0.37 0.49
Met repressor-like from SCOP 1.10 1.48
Methane monooxygenase hydrolase, gamma subunit from 3Dee 0.37 0.49
Methionine synthase domain from 3Dee 0.37 0.49
Mu transposase, DNA-binding domain from 3Dee 0.37 0.49
Nucleotidyltransferases Domain III from 3Dee 0.37 0.49
Oligomers of long helices from 3Dee 1.47 1.97
P-loop containing nucleotide triphosphate hydrolases all helical domain from 3Dee 0.37 0.49
ROP protein from 3Dee 0.37 0.49
Restriction endonucleases helical domain from 3Dee 0.37 0.49
Retroviral matrix proteins from SCOP 0.37 0.49
Spectrin repeat unit from 3Dee 0.37 0.49
T4 endonuclease V from SCOP 0.37 0.49
Thermolysin-like metalloproteases, C-terminal domain from SCOP 0.37 0.49
Thymidine phosphorylase Domain I from 3Dee 0.37 0.49
Transducin (alpha subunit), insertion domain from SCOP 0.37 0.49
Trp repressor from SCOP 0.37 0.49
Tyrosyl-tRNA synthetase, middle domain from 3Dee 0.37 0.49
Uteroglobin-like from SCOP 0.37 0.49
Winged DNA binding like from 3Dee 0.37 0.49
lambda repressor-like DNA-binding domains from SCOP 2.94 3.94
p53 tetramerization domain from SCOP 0.37 0.49
small domain attached to TIM barrel from 3Dee 0.37 0.49
the C-terminal domain of RNA polymerase alpha subunit from 3Dee 0.37 0.49

It is formed by merging the following clusters

Cluster 1

Descend tree into cluster 1

1hwga-1 [seq. related domains] All alpha 4-helical cytokines
2il6-1 [seq. related domains] All alpha 4-helical cytokines
1irl-1 [seq. related domains] All alpha 4-helical cytokines
1au1b-1 [seq. related domains] All alpha 4-helical cytokines
1lki-1 [seq. related domains] All alpha 4-helical cytokines
1rhgc-1 [seq. related domains] All alpha 4-helical cytokines
2gmfb-1 [seq. related domains] All alpha 4-helical cytokines
1hik-1 [seq. related domains] All alpha 4-helical cytokines
1hmcb-1 [seq. related domains] All alpha 4-helical cytokines
1cnt4-1 [seq. related domains] All alpha 4-helical cytokines
1hulb-2 [seq. related domains] All alpha 4-helical cytokines Short chain
1eged-1 [seq. related domains] All alpha Acyl-CoA dehydrogenase (flavoprotein), N-terminal domain
1aep-1 [seq. related domains] All alpha Apolipophorin-III
1ryt-1 [seq. related domains] All alpha Ferritin like
1bfrx-1 [seq. related domains] All alpha Ferritin like
2fha-1 [seq. related domains] All alpha Ferritin like
256ba-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1hr3b-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1eged-3 [seq. related domains] All alpha Four-helical up-and-down bundle
1vls-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1jafb-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1knyb-2 [seq. related domains] All alpha Four-helical up-and-down bundle
1hr3a-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1hmdb-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1nfo-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1hr3c-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1rmva-1 [seq. related domains] All alpha Four-helical up-and-down bundle
1a0zd-1 [seq. related domains] All alpha Globin-like
1fslb-1 [seq. related domains] All alpha Globin-like
2hbg-1 [seq. related domains] All alpha Globin-like
1allb-1 [seq. related domains] All alpha Globin-like
2hbib-1 [seq. related domains] All alpha Globin-like
1ash-1 [seq. related domains] All alpha Globin-like
1vhbb-1 [seq. related domains] All alpha Globin-like
1gnwb-2 [seq. related domains] All alpha Glutathione S-transferases, C-terminal domain
1gukb-2 [seq. related domains] All alpha Glutathione S-transferases, C-terminal domain
3tf4b-1 [seq. related domains] All beta Immunoglobulin-like beta-sandwich
1ar5b-1 [seq. related domains] All alpha Long alpha-hairpin
1sesa-1 [seq. related domains] All alpha Long alpha-hairpin
1brd-1 [seq. related domains] Membrane and cell surface proteins and peptides Membrane all-alpha
1mtyh-1 [seq. related domains] All alpha Methane monooxygenase hydrolase, gamma subunit
1bmtb-1 [seq. related domains] All alpha Methionine synthase domain
1enva-1 [seq. related domains] All alpha Oligomers of long helices
2csn-2 [seq. related domains] Alpha and beta (a+b) Protein kinases (PK), catalytic core C terminal Domain
1a06-1 [seq. related domains] Alpha and beta (a+b) Protein kinases (PK), catalytic core C terminal Domain
1vasa-1 [seq. related domains] All alpha T4 endonuclease V
1ciy-1 [seq. related domains] Membrane and cell surface proteins and peptides Toxins' membrane translocation domains
1colb-1 [seq. related domains] Membrane and cell surface proteins and peptides Toxins' membrane translocation domains
1sgk-2 [seq. related domains] Membrane and cell surface proteins and peptides Toxins' membrane translocation domains
1as3-2 [seq. related domains] All alpha Transducin (alpha subunit), insertion domain
2rsla-1 [seq. related domains] Alpha and beta (a/b) gamma,delta Resolvase, large fragment
1vdfe-1 [seq. related domains] undefined undefined
1a17-1 [seq. related domains] undefined undefined
1aa7b-1 [seq. related domains] undefined undefined
1dipb-1 [seq. related domains] undefined undefined
1aa0-1 [seq. related domains] undefined undefined
1e2ac-1 [seq. related domains] undefined undefined
1fzbd-1 [seq. related domains] undefined undefined
1mnmb-1 [seq. related domains] undefined undefined
1agrh-1 [seq. related domains] undefined undefined
1fgjb-2 [seq. related domains] undefined undefined
1higb-2 [seq. related domains] undefined undefined
1occo-4 [seq. related domains] undefined undefined
1jli-1 [seq. related domains] undefined undefined
1efrg-1 [seq. related domains] undefined undefined
1aq5c-1 [seq. related domains] undefined undefined
1bgw-4 [seq. related domains] undefined undefined
2pax-1 [seq. related domains] undefined undefined
2trt-1 [seq. related domains] undefined undefined
1lbeb-1 [seq. related domains] undefined undefined
2fusb-2 [seq. related domains] undefined undefined
1ak4d-1 [seq. related domains] undefined undefined
1maz-1 [seq. related domains] undefined undefined
1nsgb-1 [seq. related domains] undefined undefined
2a0b-1 [seq. related domains] undefined undefined
1a5t-2 [seq. related domains] undefined undefined
1wq1g-2 [seq. related domains] undefined undefined
1gtoc-1 [seq. related domains] undefined undefined

Cluster 2

Descend tree into cluster 2

1vlk-1 [seq. related domains] All alpha 4-helical cytokines Short chain
1qtqa-3 [seq. related domains] Alpha and beta (a/b) ATP pyrophosphatases extra domain
2abd-1 [seq. related domains] All alpha Acyl-CoA binding protein
1cfaa-1 [seq. related domains] All alpha Anaphylotoxins (complement system)
1aeif-3 [seq. related domains] All alpha Annexin Domain
1aeif-2 [seq. related domains] All alpha Annexin Domain
1gln-4 [seq. related domains] All alpha Anticodon-binding (C-terminal) domain of glutamyl-tRNA Domain II
1a19b-1 [seq. related domains] Alpha and beta (a/b) Barstar (barnase inhibitor)
1jtb-1 [seq. related domains] All alpha Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
1hyp-1 [seq. related domains] All alpha Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
1hssd-1 [seq. related domains] All alpha Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
1aj8b-2 [seq. related domains] All alpha Citrate synthase Domain II
3cts-2 [seq. related domains] All alpha Citrate synthase Domain II
1ab1-1 [seq. related domains] Small proteins Crambin-like
1yic-1 [seq. related domains] All alpha Cytochrome c
1gks-1 [seq. related domains] All alpha Cytochrome c
2cxbb-1 [seq. related domains] All alpha Cytochrome c
1c6s-1 [seq. related domains] All alpha Cytochrome c
2dvh-1 [seq. related domains] All alpha Cytochrome c
1cor-1 [seq. related domains] All alpha Cytochrome c
2mtac-1 [seq. related domains] All alpha Cytochrome c
1cc5-1 [seq. related domains] All alpha Cytochrome c
1etpb-2 [seq. related domains] All alpha Cytochrome c
1bnp-1 [seq. related domains] All alpha DNA polymerase beta, N-terminal (8 kD)-domain
1hstb-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
2cgpc-2 [seq. related domains] All alpha DNA-binding 3-helical bundle
1akha-2 [seq. related domains] All alpha DNA-binding 3-helical bundle
1vnd-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
2dtr-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1leb-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1hcra-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1hdp-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1ret-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1pdnc-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1bib-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1akha-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1a5j-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
2lfb-1 [seq. related domains] All alpha DNA-binding 3-helical bundle
1pdnc-2 [seq. related domains] All alpha DNA-binding 3-helical bundle
3hsf-1 [seq. related domains] Alpha and beta (a/b) DNA-binding winged domain
1awca-1 [seq. related domains] Alpha and beta (a/b) DNA-binding winged domain
1ktq-4 [seq. related domains] Alpha and beta (a/b) DNA/RNA polymerases Domain III
2dtr-2 [seq. related domains] All alpha Diphtheria toxin repressor (DtxR) dimerization domain
1acvb-2 [seq. related domains] All alpha Disulphide-bond formation facilitator (DSBA), insertion domain
2phlb-7 [seq. related domains] All alpha Double-stranded beta-helix, helical domain
2mysa-4 [seq. related domains] All alpha EF-hand
1djzb-1 [seq. related domains] All alpha EF-hand
1jsa-1 [seq. related domains] All alpha EF-hand
1ncz-1 [seq. related domains] All alpha EF-hand
5icb-1 [seq. related domains] All alpha EF-hand
1jsa-2 [seq. related domains] All alpha EF-hand
1wdca-2 [seq. related domains] All alpha EF-hand
2abk-1 [seq. related domains] All alpha Endonuclease III
2abk-2 [seq. related domains] All alpha Endonuclease III
1f36b-1 [seq. related domains] All alpha FIS protein
1lbid-3 [seq. related domains] All alpha Four-helical up-and-down bundle
2nlla-1 [seq. related domains] Small proteins Glucocorticoid receptor-like (DNA-binding domain)
1lefa-1 [seq. related domains] All alpha HMG-box
1aab-1 [seq. related domains] All alpha HMG-box
1ehs-1 [seq. related domains] Small proteins Heat-stable enterotoxin B
8cata-3 [seq. related domains] All alpha Heme-linked catalases C-terminal domain
1nol-1 [seq. related domains] All alpha Hemocyanin, N-terminal domain
1hc2-1 [seq. related domains] All alpha Hemocyanin, N-terminal domain
2yhx-1 [seq. related domains] All alpha Hexokinase all helical domain
1spzz-1 [seq. related domains] All alpha Immunoglobulin-binding protein A, fragment B
1sju-1 [seq. related domains] Small proteins Insulin-like
1ktq-2 [seq. related domains] All alpha Long alpha-hairpin
1kfd-2 [seq. related domains] All alpha Long alpha-hairpin
1grj-1 [seq. related domains] All alpha Long alpha-hairpin
1lynb-1 [seq. related domains] All alpha Lysin
1lsg-1 [seq. related domains] Alpha and beta (a+b) Lysozyme-like Domain I
256l-1 [seq. related domains] Alpha and beta (a+b) Lysozyme-like Domain I
1mntb-1 [seq. related domains] All alpha Met repressor-like
1mjlb-1 [seq. related domains] All alpha Met repressor-like
1bazd-1 [seq. related domains] All alpha Met repressor-like
1tnt-1 [seq. related domains] All alpha Mu transposase, DNA-binding domain
2bpgb-3 [seq. related domains] Alpha and beta (a+b) Nucleotidyltransferases Domain II
1bpza-1 [seq. related domains] All alpha Nucleotidyltransferases Domain III
1pyib-2 [seq. related domains] All alpha Oligomers of long helices
1afd3-1 [seq. related domains] All alpha Oligomers of long helices
1d66b-2 [seq. related domains] All alpha Oligomers of long helices
1soo-2 [seq. related domains] All alpha P-loop containing nucleotide triphosphate hydrolases all helical domain
1gtoa-1 [seq. related domains] All alpha ROP protein
1pvib-1 [seq. related domains] All alpha Restriction endonucleases helical domain
1hiws-1 [seq. related domains] All alpha Retroviral matrix proteins
1ifu-2 [seq. related domains] Alpha and beta (a+b) Ribosome inactivating proteins (RIP) Domain II
1bryz-2 [seq. related domains] Alpha and beta (a+b) Ribosome inactivating proteins (RIP) Domain II
1lxa-2 [seq. related domains] All beta Single-stranded left-handed beta-helix Domain II
2spcb-2 [seq. related domains] All alpha Spectrin repeat unit
1aonn-2 [seq. related domains] Alpha and beta (a+b) The intermediate domain of GroEL
1trlb-1 [seq. related domains] All alpha Thermolysin-like metalloproteases, C-terminal domain
1tpt-1 [seq. related domains] All alpha Thymidine phosphorylase Domain I
1tsz-2 [seq. related domains] Alpha and beta (a+b) Thymidylate synthase Extra Domain
1bhb-1 [seq. related domains] Peptides Transmembrane helical fragments
1jhga-1 [seq. related domains] All alpha Trp repressor
3ts1-2 [seq. related domains] All alpha Tyrosyl-tRNA synthetase, middle domain
1a5oa-1 [seq. related domains] Alpha and beta (a+b) Urease, gamma-subunit
1utrb-1 [seq. related domains] All alpha Uteroglobin-like
1ecl-4 [seq. related domains] All alpha Winged DNA binding like
2puga-1 [seq. related domains] All alpha lambda repressor-like DNA-binding domains
2r63-1 [seq. related domains] All alpha lambda repressor-like DNA-binding domains
1ner-1 [seq. related domains] All alpha lambda repressor-like DNA-binding domains
1uxd-1 [seq. related domains] All alpha lambda repressor-like DNA-binding domains
1au7b-1 [seq. related domains] All alpha lambda repressor-like DNA-binding domains
1lbgd-5 [seq. related domains] All alpha lambda repressor-like DNA-binding domains
1lmb4-1 [seq. related domains] All alpha lambda repressor-like DNA-binding domains
1adr-1 [seq. related domains] All alpha lambda repressor-like DNA-binding domains
1a1uc-1 [seq. related domains] All alpha p53 tetramerization domain
1cec-2 [seq. related domains] All alpha small domain attached to TIM barrel
1coo-1 [seq. related domains] All alpha the C-terminal domain of RNA polymerase alpha subunit
1ignb-1 [seq. related domains] undefined undefined
1huib-1 [seq. related domains] undefined undefined
1tc3c-1 [seq. related domains] undefined undefined
1a0p-1 [seq. related domains] undefined undefined
1jsub-1 [seq. related domains] undefined undefined
1pnbb-1 [seq. related domains] undefined undefined
2orc-1 [seq. related domains] undefined undefined
1delb-2 [seq. related domains] undefined undefined
1aa2-1 [seq. related domains] undefined undefined
1skyb-3 [seq. related domains] undefined undefined
1ignb-2 [seq. related domains] undefined undefined
1abv-1 [seq. related domains] undefined undefined
1af7-1 [seq. related domains] undefined undefined
1aup-1 [seq. related domains] undefined undefined
1yub-2 [seq. related domains] undefined undefined
1ycra-1 [seq. related domains] undefined undefined
2fokb-1 [seq. related domains] undefined undefined
1vib-1 [seq. related domains] undefined undefined
1beo-1 [seq. related domains] undefined undefined
1xgo-2 [seq. related domains] undefined undefined
2ppsl-1 [seq. related domains] undefined undefined
1sly-4 [seq. related domains] undefined undefined
1lre-1 [seq. related domains] undefined undefined
1vhrb-1 [seq. related domains] undefined undefined
1taq-2 [seq. related domains] undefined undefined
1jud-2 [seq. related domains] undefined undefined
1ddf-1 [seq. related domains] undefined undefined
2hp8-1 [seq. related domains] undefined undefined
1aoy-1 [seq. related domains] undefined undefined
1bax-1 [seq. related domains] undefined undefined
1aisb-2 [seq. related domains] undefined undefined
1gtpc-3 [seq. related domains] undefined undefined
1fts-1 [seq. related domains] undefined undefined
2hfh-1 [seq. related domains] undefined undefined
1aoa-1 [seq. related domains] undefined undefined
1tdtc-1 [seq. related domains] undefined undefined
1chkb-2 [seq. related domains] undefined undefined
2trcp-1 [seq. related domains] undefined undefined
1tbgh-1 [seq. related domains] undefined undefined
2ezi-1 [seq. related domains] undefined undefined
1nkl-1 [seq. related domains] undefined undefined
1sly-3 [seq. related domains] undefined undefined
1klmb-3 [seq. related domains] undefined undefined
1occu-1 [seq. related domains] undefined undefined
1foy-1 [seq. related domains] undefined undefined
1sfe-2 [seq. related domains] undefined undefined
1aikn-1 [seq. related domains] undefined undefined
1if1b-1 [seq. related domains] undefined undefined
2fokb-3 [seq. related domains] undefined undefined
1nirb-1 [seq. related domains] undefined undefined
1unkd-1 [seq. related domains] undefined undefined
1sknp-1 [seq. related domains] undefined undefined
1cuk-2 [seq. related domains] undefined undefined
1sly-2 [seq. related domains] undefined undefined
1ezd-2 [seq. related domains] undefined undefined
1aoa-2 [seq. related domains] undefined undefined
1ajyb-2 [seq. related domains] undefined undefined
2fokb-2 [seq. related domains] undefined undefined
1opc-1 [seq. related domains] undefined undefined
1ngr-1 [seq. related domains] undefined undefined
2fusb-1 [seq. related domains] undefined undefined
1ahjh-1 [seq. related domains] undefined undefined
1a68-1 [seq. related domains] undefined undefined
1wjdb-1 [seq. related domains] undefined undefined
2fusb-3 [seq. related domains] undefined undefined
1iba-1 [seq. related domains] undefined undefined
1afob-1 [seq. related domains] undefined undefined
1al04-1 [seq. related domains] undefined undefined
1ytfc-1 [seq. related domains] undefined undefined
1gnd-2 [seq. related domains] undefined undefined
1exnb-2 [seq. related domains] undefined undefined
1jkw-2 [seq. related domains] undefined undefined
1ns1b-1 [seq. related domains] undefined undefined
1c52-1 [seq. related domains] undefined undefined
1skye-3 [seq. related domains] undefined undefined
2ezl-1 [seq. related domains] undefined undefined
1ab3-1 [seq. related domains] undefined undefined
1aum-1 [seq. related domains] undefined undefined
1pmi-2 [seq. related domains] undefined undefined
1jkw-1 [seq. related domains] undefined undefined
1crkd-1 [seq. related domains] undefined undefined
1chkb-1 [seq. related domains] undefined undefined
1jsub-2 [seq. related domains] undefined undefined
2af8-1 [seq. related domains] undefined undefined

Enter PDB code - optionally suffixing the code with the chain id.

3dee@compbio.dundee.ac.uk