| Fold | number of domains in representative set
| number of domains in representative set as a % | number of domains in entire database | number of domains in entire database as a % |
|---|
| ATP pyrophosphatases from 3Dee | 4 | 0.23 | 24 | 0.13 |
| ATP pyrophosphatases extra domain from 3Dee | 1 | 0.06 | 7 | 0.04 |
| ATP pyrophosphatases inserted Domain I from 3Dee | 2 | 0.12 | 8 | 0.04 |
| Aconitase, Domain I from 3Dee | 1 | 0.06 | 13 | 0.07 |
| Aconitase, Domain II from 3Dee | 1 | 0.06 | 13 | 0.07 |
| Aconitase, Domain III from 3Dee | 1 | 0.06 | 13 | 0.07 |
| Alkaline phosphatase from 3Dee | 1 | 0.06 | 36 | 0.19 |
| Aspartate carbamoyltransferase, Catalytic-chain from 3Dee | 2 | 0.12 | 134 | 0.71 |
Barstar (barnase inhibitor) from SCOP  | 1 | 0.06 | 11 | 0.06 |
| Biotin carboxylase N-terminal domain-like from SCOP | 3 | 0.17 | 9 | 0.05 |
| Catalytic domain of malonyl-CoA ACP transacylase from SCOP | 1 | 0.06 | 1 | 0.01 |
| Cellulases from SCOP | 2 | 0.12 | 4 | 0.02 |
| CheB methylesterase domain (C-terminal residues 152-349) from 3Dee | 1 | 0.06 | 3 | 0.02 |
| Class I glutamine amidotransferases from 3Dee | 1 | 0.06 | 12 | 0.06 |
| CoA-dependent acetyltransferases from 3Dee | 2 | 0.12 | 15 | 0.08 |
| Cytidine deaminase from SCOP | 2 | 0.12 | 8 | 0.04 |
| DNA-binding winged domain from 3Dee | 2 | 0.12 | 12 | 0.06 |
| DNA/RNA polymerases Domain III from 3Dee | 1 | 0.06 | 22 | 0.12 |
| Dihydrofolate reductases from SCOP | 2 | 0.12 | 92 | 0.49 |
| FAD (also NAD)-binding motif from 3Dee | 11 | 0.64 | 129 | 0.68 |
| Ferredoxin reductase-like, C-terminal NADP-linked domain from SCOP | 4 | 0.23 | 15 | 0.08 |
| Flavodoxin-like from SCOP | 13 | 0.76 | 154 | 0.81 |
| Glucosamine 6-phosphate deaminase from SCOP | 1 | 0.06 | 6 | 0.03 |
| Glutaminase/Asparaginase Domain I from 3Dee | 1 | 0.06 | 17 | 0.09 |
| Glutaminase/Asparaginase Domain II from 3Dee | 1 | 0.06 | 17 | 0.09 |
| Glycinamide ribonucleotide transformylase Domain I from 3Dee | 1 | 0.06 | 7 | 0.04 |
| Glycinamide ribonucleotide transformylase Domain II from 3Dee | 1 | 0.06 | 7 | 0.04 |
| Insertion in Thioredoxin-like Domain of Glutathione Peroxidase from 3Dee | 1 | 0.06 | 2 | 0.01 |
| Integrin A (or I) domain from SCOP | 1 | 0.06 | 11 | 0.06 |
| Interleukin-1beta converting enzyme (a cysteine protease) from 3Dee | 1 | 0.06 | 8 | 0.04 |
| Leucine aminopeptidase, N-terminal domain from SCOP | 1 | 0.06 | 8 | 0.04 |
| N-carbamoylsarcosine amidohydrolase from 3Dee | 1 | 0.06 | 4 | 0.02 |
| NAD(P)-binding Rossmann-fold domains from SCOP | 13 | 0.76 | 260 | 1.38 |
| Nitrogenase iron-molybdenum protein, alpha and beta chains domain III from 3Dee | 2 | 0.12 | 16 | 0.08 |
| Nitrogenase iron-molybdenum protein, alpha chain domain I from 3Dee | 1 | 0.06 | 8 | 0.04 |
| Nitrogenase iron-molybdenum protein, beta and alpha chains domain II from 3Dee | 1 | 0.06 | 16 | 0.08 |
| Nitrogenase iron-molybdenum protein, beta chain domain I from 3Dee | 1 | 0.06 | 8 | 0.04 |
| Nucleotidyltransferases Domain I from 3Dee | 2 | 0.12 | 109 | 0.58 |
| P-loop containing nucleotide triphosphate hydrolases from SCOP | 11 | 0.64 | 156 | 0.83 |
| PLP-dependent transferases Domain I from 3Dee | 1 | 0.06 | 75 | 0.40 |
| PLP-dependent transferases Domain II from 3Dee | 4 | 0.23 | 104 | 0.55 |
| PLP-dependent transferases Domain III from 3Dee | 1 | 0.06 | 8 | 0.04 |
| PLP-dependent transferases smaller domain from 3Dee | 3 | 0.17 | 29 | 0.15 |
| Periplasmic binding protein-like I Domain I from 3Dee | 6 | 0.35 | 94 | 0.50 |
| Periplasmic binding protein-like I Domain II from 3Dee | 5 | 0.29 | 94 | 0.50 |
| Periplasmic binding protein-like II Domain I from 3Dee | 9 | 0.52 | 87 | 0.46 |
| Periplasmic binding protein-like II Domain II from 3Dee | 11 | 0.64 | 90 | 0.48 |
| Phosphofructokinase Domain I from 3Dee | 1 | 0.06 | 12 | 0.06 |
| Phosphofructokinase Domain II from 3Dee | 1 | 0.06 | 12 | 0.06 |
| Phosphoglucomutase, first 3 domains from SCOP | 3 | 0.17 | 24 | 0.13 |
| Phosphoglycerate kinase Domain I from 3Dee | 2 | 0.12 | 9 | 0.05 |
| Phosphoglycerate kinase Domain II from 3Dee | 2 | 0.12 | 9 | 0.05 |
| Phosphoglycerate mutase-like from SCOP | 3 | 0.17 | 12 | 0.06 |
| Phosphoribosyltransferases (PRTases) from 3Dee | 3 | 0.17 | 34 | 0.18 |
| Phosphotyrosine protein phosphatases I from 3Dee | 1 | 0.06 | 3 | 0.02 |
| Phosphotyrosine protein phosphatases II from 3Dee | 2 | 0.12 | 17 | 0.09 |
| Purine and uridine phosphorylases from 3Dee | 2 | 0.12 | 16 | 0.08 |
| Pyruvate kinase, C-terminal domain from SCOP | 2 | 0.12 | 9 | 0.05 |
| Pyruvate oxidase and decarboxylase, middle domain from 3Dee | 2 | 0.12 | 11 | 0.06 |
| Restriction endonucleases from 3Dee | 4 | 0.23 | 31 | 0.16 |
| Rhodanese from 3Dee | 2 | 0.12 | 8 | 0.04 |
| Ribonuclease H-like motif from SCOP | 18 | 1.05 | 137 | 0.73 |
| S-adenosyl-L-methionine-dependent methyltransferases Domain I from 3Dee | 1 | 0.06 | 7 | 0.04 |
| S-adenosyl-L-methionine-dependent methyltransferases Domain II from 3Dee | 1 | 0.06 | 7 | 0.04 |
| Subtilases from SCOP | 1 | 0.06 | 56 | 0.30 |
| Sugar phosphatases alpha/beta C terminal domain from 3Dee | 3 | 0.17 | 76 | 0.40 |
| The "swivelling" beta/beta/alpha domain from SCOP | 3 | 0.17 | 52 | 0.28 |
| Thiamin-binding from 3Dee | 6 | 0.35 | 46 | 0.24 |
| Thiolase Domain I from 3Dee | 1 | 0.06 | 4 | 0.02 |
| Thiolase Domain II from 3Dee | 1 | 0.06 | 4 | 0.02 |
| Thioredoxin-like from 3Dee | 7 | 0.41 | 142 | 0.75 |
| Thymidine phosphorylase Domain II - Rossmann-fold like from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Transketolase, C-terminal domain from 3Dee | 1 | 0.06 | 12 | 0.06 |
| Trimethylamine dehydrogenase, middle domain from 3Dee | 1 | 0.06 | 2 | 0.01 |
| Tryptophan synthase, beta-subunit Domain I from 3Dee | 1 | 0.06 | 9 | 0.05 |
| Tryptophan synthase, beta-subunit Domain II from 3Dee | 1 | 0.06 | 9 | 0.05 |
| Type I DNA topoisomerase Rossmann-fold like domain from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Uracil-DNA glycosylase from 3Dee | 1 | 0.06 | 5 | 0.03 |
| Zn-dependent exopeptidases from 3Dee | 4 | 0.23 | 37 | 0.20 |
| alpha/beta-Hydrolases from SCOP | 9 | 0.52 | 93 | 0.49 |
| beta-Glucosyltransferase & glycogen phosphorylase Domain I from 3Dee | 2 | 0.12 | 51 | 0.27 |
| beta-Glucosyltransferase & glycogen phosphorylase Domain II from 3Dee | 2 | 0.12 | 51 | 0.27 |
| beta/alpha (TIM)-barrel from 3Dee | 37 | 2.16 | 544 | 2.88 |
| gamma,delta Resolvase, large fragment from 3Dee | 1 | 0.06 | 6 | 0.03 |
| Total | 274 | 15.98 | 3535 | 18.71 |
