| Fold | number of domains in representative set
| number of domains in representative set as a % | number of domains in entire database | number of domains in entire database as a % |
|---|
4-helical cytokines from SCOP  | 10 | 0.58 | 54 | 0.29 |
| 4-helical cytokines Short chain from 3Dee | 2 | 0.12 | 8 | 0.04 |
| 4-helical cytokines fragment from 3Dee | 1 | 0.06 | 4 | 0.02 |
| 6-phosphogluconate & Acyl-CoA dehydrogenases, C-terminal domain from 3Dee | 1 | 0.06 | 5 | 0.03 |
| Acyl carrier protein from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Acyl-CoA binding protein from 3Dee | 1 | 0.06 | 2 | 0.01 |
| Acyl-CoA dehydrogenase (flavoprotein), N-terminal domain from 3Dee | 1 | 0.06 | 22 | 0.12 |
| Aldehyde ferredoxin oxidoreductase, C-terminal domain from 3Dee | 1 | 0.06 | 2 | 0.01 |
| Aldehyde ferredoxin oxidoreductase, middle domain from 3Dee | 1 | 0.06 | 2 | 0.01 |
| Anaphylotoxins (complement system) from SCOP | 1 | 0.06 | 3 | 0.02 |
| Annexin Domain from 3Dee | 2 | 0.12 | 115 | 0.61 |
| Anticodon-binding (C-terminal) domain of glutamyl-tRNA Domain I from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Anticodon-binding (C-terminal) domain of glutamyl-tRNA Domain II from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Apolipophorin-III from SCOP | 1 | 0.06 | 1 | 0.01 |
| Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin from SCOP | 3 | 0.17 | 13 | 0.07 |
| Bluetongue virus coat protein vp7 (BTV-10 vp7), alpha-helical domain from SCOP | 1 | 0.06 | 6 | 0.03 |
| Chorismate mutase II from SCOP | 2 | 0.12 | 12 | 0.06 |
| Citrate synthase Domain I from 3Dee | 2 | 0.12 | 23 | 0.12 |
| Citrate synthase Domain II from 3Dee | 2 | 0.12 | 23 | 0.12 |
| Cytochrome P450 from SCOP | 2 | 0.12 | 34 | 0.18 |
| Cytochrome c from SCOP | 9 | 0.52 | 81 | 0.43 |
| DNA polymerase beta, N-terminal (8 kD)-domain from 3Dee | 1 | 0.06 | 6 | 0.03 |
| DNA-binding 3-helical bundle from 3Dee | 15 | 0.87 | 77 | 0.41 |
| Diphtheria toxin repressor (DtxR) dimerization domain from 3Dee | 1 | 0.06 | 4 | 0.02 |
| Disulphide-bond formation facilitator (DSBA), insertion domain from SCOP | 1 | 0.06 | 15 | 0.08 |
| Double-stranded beta-helix, helical domain from 3Dee | 1 | 0.06 | 27 | 0.14 |
| EF-hand from 3Dee | 9 | 0.52 | 182 | 0.96 |
| Ectatomin, A & B chains from SCOP | 1 | 0.06 | 2 | 0.01 |
| Endonuclease III from 3Dee | 2 | 0.12 | 2 | 0.01 |
| FIS protein from 3Dee | 1 | 0.06 | 10 | 0.05 |
| Ferritin like from 3Dee | 6 | 0.35 | 79 | 0.42 |
| Four-helical up-and-down bundle from SCOP | 12 | 0.70 | 101 | 0.53 |
| Globin-like from SCOP | 7 | 0.41 | 457 | 2.42 |
| Glutathione S-transferases, C-terminal domain from SCOP | 2 | 0.12 | 90 | 0.48 |
| Glycosyltransferases of the superhelical fold Domain I from 3Dee | 2 | 0.12 | 16 | 0.08 |
| Glycosyltransferases of the superhelical fold Domain II from 3Dee | 2 | 0.12 | 16 | 0.08 |
| GroEL, the ATPase domain from 3Dee | 1 | 0.06 | 36 | 0.19 |
| HMG-box from SCOP | 2 | 0.12 | 11 | 0.06 |
| Helix-loop-helix DNA-binding domain from SCOP | 1 | 0.06 | 4 | 0.02 |
| Heme-dependent peroxidases Domain I from 3Dee | 2 | 0.12 | 73 | 0.39 |
| Heme-dependent peroxidases Domain II from 3Dee | 2 | 0.12 | 73 | 0.39 |
| Heme-linked catalases C-terminal domain from 3Dee | 1 | 0.06 | 7 | 0.04 |
| Heme-linked catalases N-terminal fragment from 3Dee | 1 | 0.06 | 11 | 0.06 |
| Hemocyanin, N-terminal domain from SCOP | 2 | 0.12 | 11 | 0.06 |
| Hemocyanin, middle domain I from 3Dee | 4 | 0.23 | 11 | 0.06 |
| Hemocyanin, middle domain II from 3Dee | 1 | 0.06 | 11 | 0.06 |
| Hexokinase all helical domain from 3Dee | 1 | 0.06 | 2 | 0.01 |
| Histone-fold from SCOP | 2 | 0.12 | 4 | 0.02 |
| Immunoglobulin-binding protein A, fragment B from 3Dee | 2 | 0.12 | 12 | 0.06 |
| Inserted domain into FAD (also NAD)-binding motif for Glucose oxidase from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Isoprenyl diphosphate synthases from 3Dee | 1 | 0.06 | 5 | 0.03 |
| Lipoxigenase-1, A DNA topoisomerase I domain from 3Dee | 1 | 0.06 | 3 | 0.02 |
| Lipoxigenase-1, C-terminal domain from 3Dee | 1 | 0.06 | 3 | 0.02 |
| Long alpha-hairpin from SCOP | 6 | 0.35 | 58 | 0.31 |
| Lysin from SCOP | 1 | 0.06 | 3 | 0.02 |
| Met repressor-like from SCOP | 3 | 0.17 | 32 | 0.17 |
| Methane monooxygenase hydrolase, gamma subunit from 3Dee | 1 | 0.06 | 6 | 0.03 |
| Methionine synthase domain from 3Dee | 1 | 0.06 | 2 | 0.01 |
| Mu transposase, DNA-binding domain from 3Dee | 1 | 0.06 | 2 | 0.01 |
| N-terminal nucleophile aminohydrolases (Ntn hydrolases) B chain Domain from 3Dee | 1 | 0.06 | 20 | 0.11 |
| Nucleotidyltransferases Domain III from 3Dee | 1 | 0.06 | 103 | 0.55 |
| Oligomers of long helices from 3Dee | 15 | 0.87 | 84 | 0.44 |
| P-loop containing nucleotide triphosphate hydrolases all helical domain from 3Dee | 1 | 0.06 | 17 | 0.09 |
| Peripheral subunit-binding domain of 2-oxo acid dehydrogenase domain from 3Dee | 2 | 0.12 | 5 | 0.03 |
| Pheromone proteins from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Phospholipase A2 from 3Dee | 2 | 0.12 | 70 | 0.37 |
| Photosynthetic reaction centre (cytochrome subunit) from 3Dee | 1 | 0.06 | 4 | 0.02 |
| Prokaryotic histone-like protein from 3Dee | 2 | 0.12 | 8 | 0.04 |
| Pyruvate oxidase and decarboxylase, C terminal domain from 3Dee | 1 | 0.06 | 4 | 0.02 |
| ROP protein from 3Dee | 1 | 0.06 | 5 | 0.03 |
| Restriction endonucleases helical domain from 3Dee | 1 | 0.06 | 4 | 0.02 |
| Retroviral matrix proteins from SCOP | 1 | 0.06 | 8 | 0.04 |
| Spectrin repeat unit from 3Dee | 1 | 0.06 | 5 | 0.03 |
| T4 endonuclease V from SCOP | 1 | 0.06 | 5 | 0.03 |
| Thermolysin-like metalloproteases, C-terminal domain from SCOP | 2 | 0.12 | 24 | 0.13 |
| Thymidine phosphorylase Domain I from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Transducin (alpha subunit), insertion domain from SCOP | 1 | 0.06 | 23 | 0.12 |
| Trp repressor from SCOP | 1 | 0.06 | 16 | 0.08 |
| Tyrosyl-tRNA synthetase, middle domain from 3Dee | 1 | 0.06 | 8 | 0.04 |
| Uteroglobin-like from SCOP | 1 | 0.06 | 6 | 0.03 |
| Winged DNA binding like from 3Dee | 2 | 0.12 | 2 | 0.01 |
| beta-Lactamase/D-ala carboxypeptidase Domain II from 3Dee | 1 | 0.06 | 23 | 0.12 |
| beta-Lactamase/D-ala carboxypeptidasea inserted domain from 3Dee | 1 | 0.06 | 4 | 0.02 |
| lambda repressor-like DNA-binding domains from SCOP | 8 | 0.47 | 61 | 0.32 |
| p53 tetramerization domain from SCOP | 1 | 0.06 | 50 | 0.26 |
| small domain attached to TIM barrel from 3Dee | 2 | 0.12 | 4 | 0.02 |
| the C-terminal domain of RNA polymerase alpha subunit from 3Dee | 1 | 0.06 | 1 | 0.01 |
| Total | 203 | 11.84 | 2444 | 12.93 |
