HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 1.0 1991 PDBID 0_T0 DATE file generated on 13-Aug-98 SEQBASE temphssp PARAMETER CONVERTSEQ of 0_T0 THRESHOLD according to: ALL REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991). CONTACT e-mail (INTERNET) Schneider@EMBL-Heidelberg.DE or Sander@EMBL-Heidelberg.DE / fax +49-6221-387306 AVAILABLE Free academic use. Commercial users must apply for license. AVAILABLE No inclusion in other databanks without permission. HEADER COMPND SOURCE AUTHOR SEQLENGTH 456 NCHAIN 1 chain(s) in 0_T0 data set NALIGN 7 NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry NOTATION : %IDE: percentage of residue identity of the alignment NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein NOTATION : LALI: length of the alignment excluding insertions and deletions NOTATION : NGAP: number of insertions and deletions in the alignment NOTATION : LGAP: total length of all insertions and deletions NOTATION : LSEQ2: length of the entire sequence of the aligned protein NOTATION : ACCNUM: SwissProt accession number NOTATION : PROTEIN: one-line description of aligned protein NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983) NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their NOTATION : acid/amide form in proportion to their database frequencies NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence) NOTATION : NDEL: number of sequences with a deletion in the test protein at this position NOTATION : NINS: number of sequences with an insertion in the test protein at this position NOTATION : ENTROPY: entropy measure of sequence variability at this position NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100 NOTATION : WEIGHT: conservation weight ## PROTEINS : EMBL/SWISSPROT identifier and alignment statistics NR. ID STRID %IDE %SIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN 1 : 1_CE 0.21 0.00 1 456 1 453 456 3 3 453 2 : 2_PL 0.25 0.00 1 456 1 448 456 4 8 448 3 : 3_HS 0.46 0.00 1 456 1 454 456 2 2 454 4 : 4_BP 0.62 0.00 11 456 1 445 446 1 1 445 5 : 5_BP 0.63 0.00 1 456 1 456 456 0 0 456 6 : 6_S1 0.19 0.00 1 453 1 443 453 7 10 443 7 : 7_S1 0.18 0.00 1 451 1 439 451 8 12 439 ## ALIGNMENTS 1 - 7 SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7 1 1 V 0 0 0 7 50 YEA TET 2 2 N 0 0 0 7 48 EFN NTG 3 3 P 0 0 0 7 30 APP PVA 4 4 G 0 0 0 7 22 GGG GGL 5 5 V 0 0 0 7 46 ICL ITG 6 6 V 0 0 0 7 37 VKV VLP 7 7 V 0 0 0 7 39 CIA AAG 8 8 R 0 0 0 7 20 RRR RRG 9 9 I 0 0 0 7 11 IVI IIL 10 10 S 0 0 0 7 39 TTT TDL 11 11 Q 0 0 0 8 41 KSDQQKG 12 12 K 0 0 0 8 34 PKKKKDT 13 13 G 0 0 0 8 22 AAGGGEG 14 14 L 0 0 0 8 21 LLLLLLG 15 15 D 0 0 0 8 45 LEQDDGI 16 16 Y 0 0 0 8 45 VLYYYKL 17 17 A 0 0 0 8 26 LVAAAAA 18 18 S 0 0 0 8 51 NKACCIN 19 19 Q 0 0 0 8 8 QQQQQQE 20 20 Q 0 0 0 8 30 EEEQQnG 21 21 G 0 0 0 7 13 TGGGGg. 22 22 T 0 0 0 8 41 ALLVVGI 23 23 A 0 0 0 8 51 KRLALPL 24 24 A 0 0 0 8 41 VFAVTIA 25 25 L 0 0 0 8 26 VLLLLLG 26 26 Q 0 0 0 8 8 QEQQQQQ 27 27 K 0 0 0 8 44 TQSKKNG 28 28 E 0 0 0 8 34 AEEEEVG 29 29 L 0 0 0 8 3 FLLLLLL 30 30 K 0 0 0 8 46 QELEEGL 31 31 R 0 0 0 8 42 RTRKKTG 32 32 I 0 0 0 8 32 AIIIIVG 33 33 K 0 0 0 8 36 GTTRTtG 34 34 I 0 0 0 7 40 YILIIn. 35 35 P 0 0 0 7 15 PPPPPQ. 36 36 D 0 0 0 8 19 DDDDNGG 37 37 Y 0 0 0 8 24 VLFVFLL 38 38 S 0 0 0 8 49 SRTSSLL 39 39 D 0 0 0 8 7 GGGGGGG 40 40 S 0 0 0 8 39 EKDKNAD 41 41 F 0 0 0 8 59 RELFFGG 42 42 K 0 0 0 7 46 A.RKKGG 43 43 I 0 0 0 7 18 V.ILILL 44 44 K 0 0 0 7 48 M.PRKLL 45 45 H 0 0 0 7 57 L.HPYGG 46 46 L 0 0 0 7 45 L.VFLgg 47 47 G 0 0 0 8 0 GGGGGgg 48 48 K 0 0 0 8 47 RHRKKLV 49 49 G 0 0 0 8 48 VFGGGLL 50 50 H 0 0 0 8 54 KYRHQSG 51 51 Y 0 0 0 8 21 YYYYYYE 52 52 S 0 0 0 8 32 GNENSGG 53 53 F 0 0 0 8 44 LIFFFGG 54 54 Y 0 0 0 8 49 HSHHFLI 55 55 S 0 0 0 8 50 NESSSFL 56 56 M 0 0 0 8 40 LVLLMSS 57 57 D 0 0 0 8 49 QKKVVLT 58 58 I 0 0 0 8 9 IVIVIVV 59 59 R 0 0 0 8 45 STHRQEQ 60 60 E 0 0 0 8 37 HESSGEG 61 61 F 0 0 0 8 27 LLCFFLI 62 62 Q 0 0 0 8 43 SQEQNST 63 63 L 0 0 0 8 41 ILLLLGG 64 64 P 0 0 0 8 47 ATLPPLL 65 65 S 0 0 0 8 41 SSHNNKR 66 66 S 0 0 0 8 35 SSSPSII 67 67 Q 0 0 0 8 35 QEAQQEV 68 68 I 0 0 0 8 40 VLLIIEE 69 69 S 0 0 0 8 55 EDRRRLL 70 70 M 0 0 0 8 47 LFPLPTT 71 71 V 0 0 0 8 34 VQVQLLL 72 72 P 0 0 0 8 15 DPPPPPP 73 73 N 0 0 0 8 46 AQGNDTR 74 74 V 0 0 0 8 42 KQQVKVV 75 75 G 0 0 0 8 32 TEGGGSS 76 76 L 0 0 0 8 17 ILLLLIV 77 77 K 0 0 0 8 43 DMSRDKR 78 78 F 0 0 0 8 14 VLLVLLL 79 79 S 0 0 0 6 35 AQSSS.. 80 80 I 0 0 0 8 13 IIIIILL 81 81 S 0 0 0 8 42 QTSSRPP 82 82 N 0 0 0 8 25 NNDNDGG 83 83 A 0 0 0 8 35 VASAAVV 84 84 N 0 0 0 8 28 SSSNSGG 85 85 I 0 0 0 8 13 VLIVIVV 86 86 K 0 0 0 8 56 VGRRKQY 87 87 I 0 0 0 8 20 FLVIILL 88 88 S 0 0 0 8 40 KRQGRSS 89 89 G 0 0 0 8 46 GFGGGLL 90 90 K 0 0 0 8 46 TRRRKHY 91 91 W 0 0 0 8 44 LRWWWTT 92 92 K 0 0 0 8 26 NQKKKKR 93 93 A 0 0 0 8 42 YLVAAVV 94 94 Q 0 0 0 8 51 SLRRRSA 95 95 K 0 0 0 8 53 YYKKKLI 96 96 R 0 0 0 8 49 TWSGNhN 97 97 F 0 0 0 8 45 SFFFFsG 98 98 L 0 0 0 8 52 AFFIIGK 99 99 K 0 0 0 8 49 WYKKKPS 100 100 M 0 0 0 8 39 GDLVLLL 101 101 S 0 0 0 8 53 LGQRGVI 102 102 G 0 0 0 8 0 GGGGGGG 103 103 N 0 0 0 8 49 IYFKNLF 104 104 F 0 0 0 8 30 NIFFFLL 105 105 D 0 0 0 8 20 QNDDDQD 106 106 L 0 0 0 8 38 SAVLLLI 107 107 S 0 0 0 8 32 VSSSSAA 108 108 I 0 0 0 8 37 DAVVVAV 109 109 E 0 0 0 8 32 FEKEEEE 110 110 G 0 0 0 6 15 EGGGG.. 111 111 M 0 0 0 8 14 IVIVIVV 112 112 S 0 0 0 8 30 DSSSSNN 113 113 I 0 0 0 8 20 SIIIIVI 114 114 S 0 0 0 8 43 ARSSLST 115 115 A 0 0 0 8 38 ITVAASA 116 116 D 0 0 0 8 35 DGNDGKK 117 117 L 0 0 0 8 13 LLLLLVV 118 118 K 0 0 0 8 48 QELKNAR 119 119 L 0 0 0 8 7 ILLLLLL 120 120 G 0 0 0 8 28 NSGGGGT 121 121 S 0 0 0 8 53 TRSSYMM 122 122 N 0 0 0 7 36 ED.VDSD 123 123 P 0 0 0 8 38 LPEPPPR 124 124 T 0 0 0 5 34 t.SAA.. 125 125 S 0 0 0 8 39 aASSSRT 126 126 G 0 0 0 8 0 GGGGGGG 127 127 K 0 0 0 8 50 SRRRHTY 128 128 P 0 0 0 8 39 VMPASPP 129 129 T 0 0 0 8 43 RKTTTIR 130 130 I 0 0 0 8 27 TVVVVLL 131 131 T 0 0 0 8 42 NSTTTIV 132 132 C 0 0 0 8 52 ANACCLI 133 133 S 0 0 0 8 44 PVSSSKE 134 134 S 0 0 0 8 35 DSSSSRR 135 135 C 0 0 0 8 0 CCCCCCC 136 136 S 0 0 0 8 47 YQSSSND 137 137 S 0 0 0 8 42 LASSSTT 138 138 H 0 0 0 8 54 ASDNGLL 139 139 I 0 0 0 8 20 FVIIILL 140 140 N 0 0 0 8 40 HSANNGG 141 141 S 0 0 0 7 45 KRDRT.G 142 142 V 0 0 0 7 29 LMVAV.I 143 143 H 0 0 0 8 43 LHERRHK 144 144 V 0 0 0 8 26 LAVLIIV 145 145 H 0 0 0 8 45 HADRHSK 146 146 I 0 0 0 8 29 LFMSILL 147 147 S 0 0 0 8 48 QGSQSTL 148 148 K 0 0 0 8 37 GGGAGSR 149 149 S 0 0 0 4 33 e..SS.. 150 150 K 0 0 0 6 54 eTDWS.. 151 151 V 0 0 0 6 48 PFLGL.. 152 152 G 0 0 0 8 16 GKGGGGG 153 153 W 0 0 0 8 30 WKWWWLL 154 154 L 0 0 0 8 7 LVLLLLL 155 155 I 0 0 0 7 57 KYL.IPP 156 156 Q 0 0 0 8 37 QDNKQTN 157 157 L 0 0 0 8 21 LFLLLPL 158 158 F 0 0 0 8 20 FLFFFIV 159 159 H 0 0 0 8 52 TSHHRFD 160 160 K 0 0 0 8 37 NTNKKGN 161 161 K 0 0 0 8 51 FFQRRLL 162 162 I 0 0 0 8 7 IIIIIVV 163 163 E 0 0 0 8 31 STEEEEN 164 164 S 0 0 0 8 44 FSSSSQR 165 165 A 0 0 0 8 47 TGKSLTV 166 166 L 0 0 0 8 5 LMFLLLL 167 167 R 0 0 0 8 46 KRQRQCA 168 168 N 0 0 0 8 46 LFKNKKN 169 169 K 0 0 0 8 41 ILVTSVV 170 170 M 0 0 0 8 4 LLLMMLL 171 171 N 0 0 0 8 42 KNENTPP 172 172 S 0 0 0 8 43 RQSSRGD 173 173 Q 0 0 0 8 44 QQRKKLL 174 174 V 0 0 0 8 17 VIIIILL 175 175 C 0 0 0 8 0 CCCCCCC 176 176 E 0 0 0 8 38 NPEQEPP 177 177 K 0 0 0 8 36 EVMVVVI 178 178 V 0 0 0 8 15 ILILVVV 179 179 T 0 0 0 8 47 NYQTTDD 180 180 N 0 0 0 5 47 .HKSS.. 181 181 S 0 0 0 8 36 TASSTSV 182 182 V 0 0 0 8 17 IGVVVVV 183 183 S 0 0 0 8 42 STSSSLL 184 184 S 0 0 0 8 33 NVSSSSG 185 185 E 0 0 0 8 50 ILDKKVL 186 186 L 0 0 0 8 15 MLLLLVV 187 187 Q 0 0 0 8 33 ANQQQNN 188 188 P 0 0 0 8 38 DSPPPED 189 189 Y 0 0 0 8 36 FLYYYLQ 190 190 F 0 0 0 8 17 VLLVFLL 191 191 Q 0 0 0 8 29 QDQEQGG 192 192 T 0 0 0 8 26 TTTTTAL 193 193 L 0 0 0 8 40 RVLLLTV 194 194 P 0 0 0 8 38 APPPPLD 195 195 V 0 0 0 8 41 AVVLVSS 196 196 M 0 0 0 8 50 SRTKTLL 197 197 T 0 0 0 8 43 ISTETVV 198 198 K 0 0 0 8 51 LSERKPP 199 199 I 0 0 0 8 30 SVILLLL 200 200 D 0 0 0 8 14 DDDDDGG 201 201 S 0 0 0 8 46 GESSKPI 202 202 V 0 0 0 8 35 DLFVVLL 203 203 A 0 0 0 8 36 IVAAAGG 204 204 G 0 0 0 8 22 GGDGGSS 205 205 I 0 0 0 8 9 VIIIVVV 206 206 N 0 0 0 8 18 DDDDDEQ 207 207 Y 0 0 0 8 15 IYYYYFY 208 208 G 0 0 0 8 26 SSSSSTT 209 209 L 0 0 0 8 11 VLLLLLF 210 210 V 0 0 0 8 42 TMVVVAS 211 211 A 0 0 0 8 41 GKEAATS 212 212 P 0 0 0 8 48 ADAPPLL 213 213 P 0 0 0 8 0 PPPPPPP 214 214 A 0 0 0 8 49 VVRRRLL 215 215 T 0 0 0 8 36 IAAAAIV 216 216 T 0 0 0 8 21 TSTTTST 217 217 A 0 0 0 8 28 ATAAANG 218 218 E 0 0 0 8 39 TSQDNQE 219 219 T 0 0 0 8 52 YNMSNYF 220 220 L 0 0 0 8 7 LLLLLIL 221 221 D 0 0 0 8 11 EDEDDEE 222 222 V 0 0 0 8 38 SMVMWLL 223 223 Q 0 0 0 8 42 HDMQLDD 224 224 M 0 0 0 8 30 HFFLLIL 225 225 K 0 0 0 8 26 KRKKKNN 226 226 G 0 0 0 8 22 GGGGGPT 227 227 E 0 0 0 8 47 HAEEEIL 228 228 F 0 0 0 8 26 FFIFFVV 229 229 Y 0 0 0 8 51 TFFYFKG 230 230 S 0 0 0 8 42 HPHNSSE 231 231 E 0 0 0 8 51 KLRVLIA 232 232 N 0 0 0 8 34 NTNAAAG 233 233 H 0 0 0 7 45 .EHRHGg 234 234 H 0 0 0 8 47 VRSPRDr 235 235 N 0 0 0 8 39 SNSSSVP 236 236 P 0 0 0 8 53 EWPPPIA 237 237 P 0 0 0 8 48 ASVPPDM 238 238 P 0 0 0 8 50 FLTPPFL 239 239 F 0 0 0 8 49 PPLFFPP 240 240 A 0 0 0 8 51 LNLMAKR 241 241 P 0 0 0 8 29 RRAPPPP 242 242 P 0 0 0 8 38 AAAPPRQ 243 243 V 0 0 0 8 40 FVVPAlm 244 244 M 0 0 0 8 46 PEMMLve 245 245 E 0 0 0 8 48 PPSAAKL 246 246 F 0 0 0 8 54 GQLIFMP 247 247 P 0 0 0 8 31 LLPPPPP 248 248 A 0 0 0 8 51 LQESSPM 249 249 A 0 0 0 8 43 GEELDKG 250 250 H 0 0 0 8 28 DEHHHED 251 251 D 0 0 0 8 27 SENDDDN 252 252 R 0 0 0 8 30 RRKRRHT 253 253 M 0 0 0 8 31 MMMMMTN 254 254 V 0 0 0 8 37 LVVIVSS 255 255 Y 0 0 0 8 38 YYYYYQQ 256 256 L 0 0 0 8 19 FVFLLVL 257 257 G 0 0 0 8 41 WAAAGTA 258 258 L 0 0 0 8 20 FFIIIVI 259 259 S 0 0 0 8 11 SSSSSPS 260 260 D 0 0 0 8 35 DEDDELA 261 261 Y 0 0 0 8 36 QFYYYYN 262 262 F 0 0 0 8 21 VFVLFLF 263 263 F 0 0 0 8 5 LFFFFFL 264 264 N 0 0 0 8 19 NDNNNNS 265 265 T 0 0 0 8 26 SSTTTTS 266 266 A 0 0 0 8 33 LAAAAVV 267 267 G 0 0 0 8 50 AMSAGFL 268 268 L 0 0 0 8 56 RELLFGT 269 269 V 0 0 0 8 38 ASVVVLM 270 270 Y 0 0 0 8 36 AYYYYLL 271 271 Q 0 0 0 8 43 FFHQQQQ 272 272 E 0 0 0 8 39 QREQKTK 273 273 A 0 0 0 8 35 EAEAANQ 274 274 G 0 0 0 8 0 GGGGGGG 275 275 V 0 0 0 8 40 RAYAAAA 276 276 L 0 0 0 8 2 LLLFLLL 277 277 K 0 0 0 8 42 VQNGNDD 278 278 M 0 0 0 8 12 LLFLLLI 279 279 T 0 0 0 8 46 SLSTTDD 280 280 L 0 0 0 8 15 LLILLII 281 281 R 0 0 0 8 41 TVTRRTT 282 282 D 0 0 0 8 25 GGDDDPD 283 283 D 0 0 0 8 13 DDDDDEG 284 284 M 0 0 0 8 28 EKMMMMM 285 285 I 0 0 0 8 21 FVIIIVF 286 286 P 0 0 0 8 26 KPPPPPE 287 287 K 0 0 0 8 36 KHPKKRD 288 288 E 0 0 0 8 43 VDDEENL 289 289 S 0 0 0 8 47 LLSSSIP 290 290 K 0 0 0 8 42 EDNKKPP 291 291 F 0 0 0 8 38 TMISFLL 292 292 R 0 0 0 8 48 QLRRRTT 293 293 L 0 0 0 8 42 GLLLLTT 294 294 T 0 0 0 5 31 .RTTT.. 295 295 T 0 0 0 7 33 FATTTT. 296 296 K 0 0 0 8 38 DTKKKDS 297 297 F 0 0 0 8 44 TYSFFLT 298 298 F 0 0 0 8 39 NFFLFAL 299 299 G 0 0 0 8 32 QGRGGAG 300 300 T 0 0 0 8 52 ESPKILA 301 301 F 0 0 0 8 36 IIFALAL 302 302 L 0 0 0 8 33 FVVLIPI 303 303 P 0 0 0 7 27 Q.PPPEP 304 304 E 0 0 0 8 46 ELRQQAK 305 305 V 0 0 0 8 15 LLLVVLV 306 306 A 0 0 0 8 40 SSAAAGF 307 307 K 0 0 0 8 30 RPRKKKQ 308 308 K 0 0 0 8 47 GALMMLQ 309 309 F 0 0 0 8 37 LVYFFPY 310 310 P 0 0 0 8 17 PIPPPPP 311 311 N 0 0 0 8 33 TDNNDGE 312 312 M 0 0 0 8 49 GSMMMQs 313 313 K 0 0 0 8 40 QPNNQHp 314 314 I 0 0 0 8 26 ALLVMLL 315 315 Q 0 0 0 8 42 QKEQQLT 316 316 I 0 0 0 8 15 VLLLLLI 317 317 H 0 0 0 8 54 AEQTFSR 318 318 V 0 0 0 8 29 VLGLILI 319 319 S 0 0 0 8 42 HRSSWRQ 320 320 A 0 0 0 8 29 CVVVAVV 321 321 S 0 0 0 8 48 LLPSSMP 322 322 T 0 0 0 8 48 KASSLKN 323 323 P 0 0 0 8 30 VPAPPSP 324 324 P 0 0 0 8 0 PPPPPPP 325 325 H 0 0 0 8 48 KRLHKMT 326 326 L 0 0 0 8 32 ICLLLIV 327 327 S 0 0 0 8 39 STNTTLT 328 328 V 0 0 0 8 40 CIFTMLL 329 329 Q 0 0 0 8 32 QKSRKQQ 330 330 P 0 0 0 8 36 NPPPPNK 331 331 T 0 0 0 8 45 RSGTSKD 332 332 G 0 0 0 8 37 GGNGSKK 333 333 L 0 0 0 8 36 VTLILVA 334 334 T 0 0 0 8 45 VTSADTL 335 335 F 0 0 0 8 20 VIVLLVV 336 336 Y 0 0 0 8 49 SSDTISK 337 337 P 0 0 0 8 46 SVPAFIV 338 338 A 0 0 0 8 52 STYAVPF 339 339 V 0 0 0 8 31 VAMVLVA 340 340 D 0 0 0 8 40 ASEDDTT 341 341 V 0 0 0 8 33 VVILTIS 342 342 Q 0 0 0 8 39 TTDQQHE 343 343 A 0 0 0 8 42 FIAAAVV 344 344 F 0 0 0 8 46 RAFFFLV 345 345 A 0 0 0 8 46 FLVAASV 346 346 V 0 0 0 8 48 PVHIISS 347 347 L 0 0 0 8 47 RPLLLVQ 348 348 P 0 0 0 8 0 PPPPPPP 349 349 N 0 0 0 8 29 DDSNNQN 350 350 S 0 0 0 8 34 GQSSSGD 351 351 S 0 0 0 8 43 RPSSSTV 352 352 L 0 0 0 8 50 EEKLLPE 353 353 A 0 0 0 8 41 AVEADVT 354 354 S 0 0 0 8 46 VQPSPAT 355 355 L 0 0 0 8 26 ALVLLLI 356 356 F 0 0 0 8 29 YSFFFFC 357 357 L 0 0 0 8 49 RSRLLQL 358 358 I 0 0 0 8 18 FMLLLMI 359 359 G 0 0 0 8 36 ETSGEND 360 360 M 0 0 0 8 41 EMVLMGV 361 361 H 0 0 0 8 42 DDAKNVD 362 362 T 0 0 0 8 40 IATLLMT 363 363 T 0 0 0 8 46 IRNNNTD 364 364 G 0 0 0 8 38 TLVTLLL 365 365 S 0 0 0 8 39 TSSSSNL 366 366 M 0 0 0 8 29 VAAAVAA 367 367 E 0 0 0 8 49 QKTKVHS 368 368 V 0 0 0 8 34 AMLIVLF 369 369 S 0 0 0 8 36 SATGGVS 370 370 A 0 0 0 8 51 YLFTAPV 371 371 E 0 0 0 8 41 SRNKKSE 372 372 S 0 0 0 8 39 QGTASTG 373 373 N 0 0 0 8 38 KKSDDTD 374 374 R 0 0 0 8 24 KAKKRKK 375 375 L 0 0 0 8 6 LLILLLL 376 376 V 0 0 0 8 51 FRTVIHM 377 377 G 0 0 0 8 48 LTGGGII 378 378 E 0 0 0 8 45 HQFEESD 379 379 L 0 0 0 8 16 LLLLLLA 380 380 K 0 0 0 8 47 lDKTRSK 381 381 L 0 0 0 8 32 sLPLLLL 382 382 D 0 0 0 8 31 GRGGDED 383 383 R 0 0 0 8 14 rRKRKRK 384 384 L 0 0 0 8 24 lFVLLLT 385 385 L 0 0 0 8 53 RRKILTS 386 386 L 0 0 0 8 28 TIVLLVL 387 387 E 0 0 0 8 34 EYEEEQN 388 388 L 0 0 0 8 32 ASLLLLL 389 389 K 0 0 0 8 30 KNKKKAR 390 390 H 0 0 0 8 44 aHEHHST 391 391 S 0 0 0 8 0 sSSSSSS 392 392 N 0 0 0 8 42 NAKNDFN 393 393 I 0 0 0 8 30 LLVIISV 394 394 G 0 0 0 8 30 TEGGGQG 395 395 P 0 0 0 8 46 ESLSPPN 396 396 F 0 0 0 8 22 SLFFFFF 397 397 P 0 0 0 8 45 RANPSDD 398 398 V 0 0 0 8 37 SLAVVAV 399 399 E 0 0 0 8 48 EIEQESF 400 400 L 0 0 0 8 51 SPLLSRI 401 401 L 0 0 0 8 0 LLLLLLL 402 402 Q 0 0 0 8 17 QQEQQEE 403 403 D 0 0 0 8 42 SAAASEM 404 404 I 0 0 0 8 47 SPLLVWL 405 405 M 0 0 0 8 14 LLLMILV 406 406 N 0 0 0 8 40 RKNDNSE 407 407 Y 0 0 0 8 56 STYYYDK 408 408 I 0 0 0 8 28 LMYVVVI 409 409 V 0 0 0 8 22 ILILMVF 410 410 P 0 0 0 8 50 AQLSPRD 411 411 I 0 0 0 8 44 TINATAL 412 412 L 0 0 0 8 42 VGTVIAA 413 413 V 0 0 0 8 41 GVFVVYF 414 414 L 0 0 0 8 22 IMYLLMM 415 415 P 0 0 0 8 12 PPPPPQP 416 416 R 0 0 0 8 45 EMKKVKA 417 417 V 0 0 0 8 23 VLFVILM 418 418 N 0 0 0 8 19 MNNNNNN 419 419 E 0 0 0 8 33 SEDEKEA 420 420 K 0 0 0 8 37 RRKKKHI 421 421 L 0 0 0 8 16 LTLLLLL 422 422 Q 0 0 0 8 47 EWAQQEG 423 423 K 0 0 0 8 49 VRERKVS 424 424 G 0 0 0 8 8 AGGGGGG 425 425 F 0 0 0 8 25 FVFLFIV 426 426 P 0 0 0 8 23 TQPPPPP 427 427 L 0 0 0 8 23 AILLLLL 428 428 P 0 0 0 8 19 LPPPPPP 429 429 T 0 0 0 8 38 MLLMLKK 430 430 P 0 0 0 8 48 nPLPPII 431 431 A 0 0 0 8 52 kEKRALL 432 432 R 0 0 0 8 50 GGRKYNN 433 433 V 0 0 0 8 13 LIVVIVI 434 434 Q 0 0 0 8 27 DNQQEND 435 435 L 0 0 0 8 7 LFLLLFF 436 436 Y 0 0 0 8 45 FVYYFAS 437 437 N 0 0 0 8 25 EHDDNNN 438 438 V 0 0 0 8 47 IELLLSA 439 439 V 0 0 0 8 35 iVGVTVD 440 440 L 0 0 0 8 18 iVLLLVI 441 441 Q 0 0 0 8 40 ITQQQDD 442 442 P 0 0 0 8 46 TNIPPVV 443 443 H 0 0 0 8 43 LHHHYIL 444 444 Q 0 0 0 8 34 DAKQQEE 445 445 N 0 0 0 8 23 GGDDDND 446 446 F 0 0 0 8 36 CFFFFAL 447 447 L 0 0 0 8 7 LLLLLVL 448 448 L 0 0 0 8 29 LTFLLVV 449 449 F 0 0 0 8 11 LILLFLL 450 450 G 0 0 0 8 31 QGGGGTS 451 451 A 0 0 0 8 34 MAAAAVT 452 452 D 0 0 0 7 25 DDNNDA 453 453 V 0 0 0 7 36 FLVVVP 454 454 V 0 0 0 6 41 GHQQQ 455 455 Y 0 0 0 6 17 FFYHY 456 456 K 0 0 0 6 49 PAMGS ## SEQUENCE PROFILE AND ENTROPY SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT 1 1 14 0 0 0 0 0 14 0 14 0 0 29 0 0 0 0 0 29 0 0 7 0 0 1.550 80 1.00 2 2 0 0 0 0 14 0 0 14 0 0 0 14 0 0 0 0 0 14 43 0 7 0 0 1.475 76 1.00 3 3 14 0 0 0 0 0 0 0 29 57 0 0 0 0 0 0 0 0 0 0 7 0 0 0.956 49 1.00 4 4 0 14 0 0 0 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0.410 21 1.00 5 5 14 14 29 0 0 0 0 14 0 0 0 14 14 0 0 0 0 0 0 0 7 0 0 1.748 90 1.00 6 6 57 14 0 0 0 0 0 0 0 14 0 0 0 0 0 14 0 0 0 0 7 0 0 1.154 59 1.00 7 7 14 0 14 0 0 0 0 14 43 0 0 0 14 0 0 0 0 0 0 0 7 0 0 1.475 76 1.00 8 8 0 0 0 0 0 0 0 14 0 0 0 0 0 0 86 0 0 0 0 0 7 0 0 0.410 21 1.00 9 9 14 14 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0.796 41 1.00 10 10 0 14 0 0 0 0 0 0 0 0 14 57 0 0 0 0 0 0 0 14 7 0 0 1.154 59 1.00 11 11 0 0 0 0 0 0 0 13 0 0 13 0 0 0 0 25 38 0 0 13 8 0 0 1.494 72 1.00 12 12 0 0 0 0 0 0 0 0 0 13 0 13 0 0 0 63 0 0 0 13 8 0 0 1.074 52 1.00 13 13 0 0 0 0 0 0 0 63 25 0 0 0 0 0 0 0 0 13 0 0 8 0 0 0.900 43 1.00 14 14 0 88 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0.377 18 1.00 15 15 0 13 13 0 0 0 0 13 0 0 0 0 0 0 0 0 13 13 0 38 8 0 0 1.667 80 1.00 16 16 13 25 0 0 0 0 50 0 0 0 0 0 0 0 0 13 0 0 0 0 8 0 0 1.213 58 1.00 17 17 13 13 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0.736 35 1.00 18 18 0 0 13 0 0 0 0 0 13 0 13 0 25 0 0 13 0 0 25 0 8 0 0 1.733 83 1.00 19 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88 13 0 0 8 0 0 0.377 18 1.00 20 20 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 38 38 13 0 8 0 1 1.255 60 1.00 21 21 0 0 0 0 0 0 0 86 0 0 0 14 0 0 0 0 0 0 0 0 7 1 0 0.410 21 1.00 22 22 25 25 13 0 0 0 0 13 13 0 0 13 0 0 0 0 0 0 0 0 8 0 0 1.733 83 1.00 23 23 0 38 0 0 0 0 0 0 25 13 0 0 0 0 13 13 0 0 0 0 8 0 0 1.494 72 1.00 24 24 25 0 13 0 13 0 0 0 38 0 0 13 0 0 0 0 0 0 0 0 8 0 0 1.494 72 1.00 25 25 13 75 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0.736 35 1.00 26 26 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88 13 0 0 8 0 0 0.377 18 1.00 27 27 0 0 0 0 0 0 0 13 0 0 13 13 0 0 0 38 13 0 13 0 8 0 0 1.667 80 1.00 28 28 13 0 0 0 0 0 0 13 13 0 0 0 0 0 0 0 0 63 0 0 8 0 0 1.074 52 1.00 29 29 0 88 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0.377 18 1.00 30 30 0 25 0 0 0 0 0 13 0 0 0 0 0 0 0 13 13 38 0 0 8 0 0 1.494 72 1.00 31 31 0 0 0 0 0 0 0 13 0 0 0 25 0 0 38 25 0 0 0 0 8 0 0 1.321 64 1.00 32 32 13 0 63 0 0 0 0 13 13 0 0 0 0 0 0 0 0 0 0 0 8 0 0 1.074 52 1.00 33 33 0 0 0 0 0 0 0 25 0 0 0 50 0 0 13 13 0 0 0 0 8 0 1 1.213 58 1.00 34 34 0 14 57 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 14 0 7 1 0 1.154 59 1.00 35 35 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0 0 14 0 0 0 7 1 0 0.410 21 1.00 36 36 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 13 63 8 0 0 0.900 43 1.00 37 37 25 38 0 0 25 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 1.321 64 1.00 38 38 0 25 0 0 0 0 0 0 0 0 50 13 0 0 13 0 0 0 0 0 8 0 0 1.213 58 1.00 39 39 0 0 0 0 0 0 0 88 0 0 0 0 0 0 0 0 0 0 0 13 8 0 0 0.377 18 1.00 40 40 0 0 0 0 0 0 0 0 13 0 13 0 0 0 0 25 0 13 13 25 8 0 0 1.733 83 1.00 41 41 0 13 0 0 38 0 0 25 0 0 0 0 0 0 13 0 0 13 0 0 8 0 0 1.494 72 1.00 42 42 0 0 0 0 0 0 0 29 14 0 0 0 0 0 14 43 0 0 0 0 7 1 0 1.277 66 1.00 43 43 14 43 43 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 1 0 1.004 52 1.00 44 44 0 29 0 14 0 0 0 0 0 14 0 0 0 0 14 29 0 0 0 0 7 1 0 1.550 80 1.00 45 45 0 14 0 0 0 0 14 29 0 14 0 0 0 29 0 0 0 0 0 0 7 1 0 1.550 80 1.00 46 46 14 43 0 0 14 0 0 29 0 0 0 0 0 0 0 0 0 0 0 0 7 1 2 1.277 66 1.00 47 47 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0.000 0 1.00 48 48 13 13 0 0 0 0 0 0 0 0 0 0 0 13 25 38 0 0 0 0 8 0 0 1.494 72 1.00 49 49 13 25 0 0 13 0 0 50 0 0 0 0 0 0 0 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0 8 0 0 1.667 80 1.00 439 439 50 0 13 0 0 0 0 13 0 0 0 13 0 0 0 0 0 0 0 13 8 0 1 1.386 67 1.00 440 440 25 50 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 1.040 50 1.00 441 441 0 0 13 0 0 0 0 0 0 0 0 13 0 0 0 0 50 0 0 25 8 0 0 1.213 58 1.00 442 442 25 0 13 0 0 0 0 0 0 38 0 13 0 0 0 0 0 0 13 0 8 0 0 1.494 72 1.00 443 443 0 25 13 0 0 0 13 0 0 0 0 0 0 50 0 0 0 0 0 0 8 0 0 1.213 58 1.00 444 444 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 13 38 25 0 13 8 0 0 1.494 72 1.00 445 445 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 25 50 8 0 0 1.040 50 1.00 446 446 0 13 0 0 63 0 0 0 13 0 0 0 13 0 0 0 0 0 0 0 8 0 0 1.074 52 1.00 447 447 13 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0.377 18 1.00 448 448 25 50 0 0 13 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 8 0 0 1.213 58 1.00 449 449 0 63 13 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0.900 43 1.00 450 450 0 0 0 0 0 0 0 63 0 0 13 13 0 0 0 0 13 0 0 0 8 0 0 1.074 52 1.00 451 451 13 0 0 13 0 0 0 0 63 0 0 13 0 0 0 0 0 0 0 0 8 0 0 1.074 52 1.00 452 452 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 29 57 7 0 0 0.956 49 1.00 453 453 57 14 0 0 14 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 7 0 0 1.154 59 1.00 454 454 17 0 0 0 0 0 0 17 0 0 0 0 0 17 0 0 50 0 0 0 6 0 0 1.242 69 1.00 455 455 0 0 0 0 33 0 50 0 0 0 0 0 0 17 0 0 0 0 0 0 6 0 0 1.011 56 1.00 456 456 0 0 0 17 0 0 0 17 17 17 17 0 0 0 0 17 0 0 0 0 6 0 0 1.792 100 1.00 ## INSERTION LIST AliNo IPOS JPOS Len Sequence 1 124 124 2 tCDa 1 149 149 1 eRe 1 380 377 7 lDFQCVPAs 1 383 380 10 rAGSSANLSVAl 1 390 387 1 aVs 1 430 427 1 nSk 1 439 436 3 iNPEi 6 20 20 3 nSLVg 6 33 33 2 tSVn 6 46 46 1 gGg 6 96 95 1 hGs 6 243 235 1 lPv 7 46 45 4 gGGVLg 7 233 226 8 gDLIDYPLGr 7 243 236 1 mPe 7 312 303 1 sRp //