HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 1.0 1991 PDBID 0_T0 DATE file generated on 13-Aug-98 SEQBASE temphssp PARAMETER CONVERTSEQ of 0_T0 THRESHOLD according to: ALL REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991). CONTACT e-mail (INTERNET) Schneider@EMBL-Heidelberg.DE or Sander@EMBL-Heidelberg.DE / fax +49-6221-387306 AVAILABLE Free academic use. Commercial users must apply for license. AVAILABLE No inclusion in other databanks without permission. HEADER COMPND SOURCE AUTHOR SEQLENGTH 64 NCHAIN 1 chain(s) in 0_T0 data set NALIGN 1 NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry NOTATION : %IDE: percentage of residue identity of the alignment NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein NOTATION : LALI: length of the alignment excluding insertions and deletions NOTATION : NGAP: number of insertions and deletions in the alignment NOTATION : LGAP: total length of all insertions and deletions NOTATION : LSEQ2: length of the entire sequence of the aligned protein NOTATION : ACCNUM: SwissProt accession number NOTATION : PROTEIN: one-line description of aligned protein NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983) NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their NOTATION : acid/amide form in proportion to their database frequencies NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence) NOTATION : NDEL: number of sequences with a deletion in the test protein at this position NOTATION : NINS: number of sequences with an insertion in the test protein at this position NOTATION : ENTROPY: entropy measure of sequence variability at this position NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100 NOTATION : WEIGHT: conservation weight ## PROTEINS : EMBL/SWISSPROT identifier and alignment statistics NR. ID STRID %IDE %SIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN 1 : 1_EA 0.84 0.00 1 63 1 63 63 0 0 63 ## ALIGNMENTS 1 - 1 SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7 1 1 G 0 0 0 2 0 G 2 2 A 0 0 0 2 56 K 3 3 K 0 0 0 2 0 K 4 4 E 0 0 0 2 0 E 5 5 P 0 0 0 2 0 p 6 6 D 0 0 0 2 0 d 7 7 P 0 0 0 2 0 P 8 8 D 0 0 0 2 0 D 9 9 K 0 0 0 2 0 K 10 10 L 0 0 0 2 0 L 11 11 K 0 0 0 2 0 K 12 12 K 0 0 0 2 0 K 13 13 A 0 0 0 2 0 A 14 14 I 0 0 0 2 0 I 15 15 V 0 0 0 2 15 I 16 16 Q 0 0 0 2 0 Q 17 17 V 0 0 0 2 0 V 18 18 E 0 0 0 2 44 K 19 19 H 0 0 0 2 0 H 20 20 D 0 0 0 2 0 D 21 21 E 0 0 0 2 19 D 22 22 R 0 0 0 2 0 R 23 23 P 0 0 0 2 0 P 24 24 A 0 0 0 2 0 A 25 25 R 0 0 0 2 0 R 26 26 L 0 0 0 2 0 L 27 27 I 0 0 0 2 0 I 28 28 L 0 0 0 2 0 L 29 29 N 0 0 0 2 0 N 30 30 R 0 0 0 2 0 R 31 31 R 0 0 0 2 0 R 32 32 P 0 0 0 2 0 P 33 33 P 0 0 0 2 0 P 34 34 A 0 0 0 2 0 A 35 35 E 0 0 0 2 0 E 36 36 G 0 0 0 2 0 G 37 37 Y 0 0 0 2 15 W 38 38 A 0 0 0 2 0 A 39 39 W 0 0 0 2 0 W 40 40 L 0 0 0 2 0 L 41 41 K 0 0 0 2 0 K 42 42 Y 0 0 0 2 0 Y 43 43 E 0 0 0 2 0 E 44 44 D 0 0 0 2 0 D 45 45 D 0 0 0 2 0 D 46 46 G 0 0 0 2 0 G 47 47 Q 0 0 0 2 0 Q 48 48 E 0 0 0 2 0 E 49 49 F 0 0 0 2 0 F 50 50 E 0 0 0 2 0 E 51 51 A 0 0 0 2 0 A 52 52 N 0 0 0 2 30 D 53 53 L 0 0 0 2 0 L 54 54 A 0 0 0 2 30 G 55 55 D 0 0 0 2 48 T 56 56 V 0 0 0 2 0 V 57 57 K 0 0 0 2 41 Q 58 58 L 0 0 0 2 0 L 59 59 V 0 0 0 2 0 V 60 60 A 0 0 0 2 0 A 61 61 L 0 0 0 2 0 L 62 62 I 0 0 0 2 26 L 63 63 E 0 0 0 2 0 E 64 64 G 0 0 0 1 0 ## SEQUENCE PROFILE AND ENTROPY SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT 1 1 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 2 2 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 50 0 0 0 0 2 0 0 0.693 100 1.00 3 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 2 0 0 0.000 0 1.00 4 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2 0 0 0.000 0 1.00 5 5 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 2 0 1 0.000 0 1.00 6 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 2 0 0 0.000 0 1.00 7 7 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 2 0 0 0.000 0 1.00 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 2 0 0 0.000 0 1.00 10 10 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 11 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 2 0 0 0.000 0 1.00 12 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 2 0 0 0.000 0 1.00 13 13 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 14 14 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 15 15 50 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.693 100 1.00 16 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 2 0 0 0.000 0 1.00 17 17 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 18 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 50 0 0 2 0 0 0.693 100 1.00 19 19 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 2 0 0 0.000 0 1.00 20 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 2 0 0 0.000 0 1.00 21 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 50 2 0 0 0.693 100 1.00 22 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2 0 0 0.000 0 1.00 23 23 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 24 24 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 25 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2 0 0 0.000 0 1.00 26 26 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 27 27 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 28 28 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 29 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 2 0 0 0.000 0 1.00 30 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2 0 0 0.000 0 1.00 31 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2 0 0 0.000 0 1.00 32 32 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 33 33 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 34 34 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 35 35 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2 0 0 0.000 0 1.00 36 36 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 37 37 0 0 0 0 0 50 50 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.693 100 1.00 38 38 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 39 39 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 40 40 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 41 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 2 0 0 0.000 0 1.00 42 42 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 43 43 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2 0 0 0.000 0 1.00 44 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 2 0 0 0.000 0 1.00 45 45 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 2 0 0 0.000 0 1.00 46 46 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 47 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 2 0 0 0.000 0 1.00 48 48 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2 0 0 0.000 0 1.00 49 49 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 50 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2 0 0 0.000 0 1.00 51 51 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 52 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 50 2 0 0 0.693 100 1.00 53 53 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 54 54 0 0 0 0 0 0 0 50 50 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.693 100 1.00 55 55 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 50 2 0 0 0.693 100 1.00 56 56 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 57 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 50 0 0 0 2 0 0 0.693 100 1.00 58 58 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 59 59 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 60 60 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 61 61 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.000 0 1.00 62 62 0 50 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0.693 100 1.00 63 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2 0 0 0.000 0 1.00 64 64 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0.000 0 1.00 ## INSERTION LIST AliNo IPOS JPOS Len Sequence 1 5 5 3 pKEAd //