HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 1.0 1991 PDBID 0_T0 DATE file generated on 13-Aug-98 SEQBASE temphssp PARAMETER CONVERTSEQ of 0_T0 THRESHOLD according to: ALL REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991). CONTACT e-mail (INTERNET) Schneider@EMBL-Heidelberg.DE or Sander@EMBL-Heidelberg.DE / fax +49-6221-387306 AVAILABLE Free academic use. Commercial users must apply for license. AVAILABLE No inclusion in other databanks without permission. HEADER COMPND SOURCE AUTHOR SEQLENGTH 419 NCHAIN 1 chain(s) in 0_T0 data set NALIGN 11 NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry NOTATION : %IDE: percentage of residue identity of the alignment NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein NOTATION : LALI: length of the alignment excluding insertions and deletions NOTATION : NGAP: number of insertions and deletions in the alignment NOTATION : LGAP: total length of all insertions and deletions NOTATION : LSEQ2: length of the entire sequence of the aligned protein NOTATION : ACCNUM: SwissProt accession number NOTATION : PROTEIN: one-line description of aligned protein NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983) NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their NOTATION : acid/amide form in proportion to their database frequencies NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence) NOTATION : NDEL: number of sequences with a deletion in the test protein at this position NOTATION : NINS: number of sequences with an insertion in the test protein at this position NOTATION : ENTROPY: entropy measure of sequence variability at this position NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100 NOTATION : WEIGHT: conservation weight ## PROTEINS : EMBL/SWISSPROT identifier and alignment statistics NR. ID STRID %IDE %SIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN 1 : 1_MU 0.44 0.00 1 412 1 409 412 3 3 409 2 : 2_PH 0.21 0.00 1 419 1 408 419 6 11 408 3 : 3_AR 0.20 0.00 1 419 1 408 419 6 11 408 4 : 4_TP 0.34 0.00 1 417 1 415 417 2 2 415 5 : 5_AE 0.36 0.00 1 413 1 411 413 2 2 411 6 : 6_A6 0.50 0.00 1 419 1 417 419 2 2 417 7 : 7_MU 0.46 0.00 1 419 1 417 419 2 2 417 8 : 8_MU 0.59 0.00 1 418 1 418 418 0 0 418 9 : 9_MU 0.75 0.00 1 419 1 419 419 0 0 419 10 : 10_MU 0.50 0.00 1 419 1 417 419 2 2 417 11 : 11_MU 0.48 0.00 1 419 1 417 419 2 2 417 ## ALIGNMENTS 1 - 11 SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7 1 1 M 0 0 0 12 18 AMLMMMMMMQM 2 2 D 0 0 0 12 27 EEESHEEDDTD 3 3 K 0 0 0 12 44 RKSCSKKKKVF 4 4 F 0 0 0 12 19 FLLYYILFFIL 5 5 R 0 0 0 12 50 VTTRIINVREE 6 6 V 0 0 0 12 15 VLLVVVIIVII 7 7 Q 0 0 0 12 48 TTHEERAQYEV 8 8 G 0 0 0 12 17 GPPGGGGGGGG 9 9 P 0 0 0 12 45 GIIGGGGGQRQ 10 10 T 0 0 0 12 53 NSAFYQDVSAV 11 11 R 0 0 0 12 40 RRLPKKSKRSP 12 12 L 0 0 0 12 15 LVIVILLLLLL 13 13 Q 0 0 0 12 38 SENSGNNESKK 14 14 G 0 0 0 12 0 GGGGGGGGGGG 15 15 E 0 0 0 12 37 EETCQTTESEE 16 16 V 0 0 0 12 7 VIVIIVVVVVV 17 17 T 0 0 0 12 41 TNNRTKHRNRE 18 18 I 0 0 0 12 22 VLLVAVIIIII 19 19 S 0 0 0 12 30 GPPCSESSSSS 20 20 G 0 0 0 12 0 GGGGGGGGGGG 21 21 A 0 0 0 12 28 ASSNNAAAAAA 22 22 K 0 0 0 12 0 KKKKKKKKKKK 23 23 N 0 0 0 12 17 NSSNNNNNNNN 24 24 A 0 0 0 12 36 SLVAAASAASS 25 25 A 0 0 0 12 28 VSSAAVAAAAA 26 26 L 0 0 0 12 30 LNNLLLVLLLL 27 27 P 0 0 0 12 32 KRRPPPAPPAP 28 28 I 0 0 0 12 42 LAACCVLLIII 29 29 L 0 0 0 12 15 MLLIIIILLML 30 30 F 0 0 0 12 40 ALLALAPAFAA 31 31 A 0 0 0 12 27 ALLAAAAAAGA 32 32 A 0 0 0 12 30 TAAAASTMATT 33 33 L 0 0 0 12 31 LAAVLLIIIIL 34 34 L 0 0 0 12 0 LLLLLLLLLLL 35 35 A 0 0 0 12 24 AAATTAAAACS 36 36 E 0 0 0 12 39 ETEQDsNDTSR 37 37 E 0 0 0 12 31 GGGEEeSTEDQ 38 38 P 0 0 0 12 39 TTTPEKEPPDE 39 39 V 0 0 0 12 36 STTVVSVIVCV 40 40 E 0 0 0 12 49 TQQLIVTTKRK 41 41 I 0 0 0 12 15 IVLLLIILLLI 42 42 Q 0 0 0 12 45 TTNQECEKTSK 43 43 N 0 0 0 12 17 NNNNNDGNNNS 44 44 V 0 0 0 12 24 CLLVIVLVVLL 45 45 P 0 0 0 12 26 PLLPPPPPPPP 46 46 K 0 0 0 12 30 DDDDNTEDEAQ 47 47 L 0 0 0 12 35 ISSIILILLLV 48 48 K 0 0 0 12 48 LDDENSSKKAV 49 49 D 0 0 0 12 0 DDDDDDDDDDD 50 50 I 0 0 0 12 8 VIIVVVIVIII 51 51 D 0 0 0 12 47 PRRAKYEREDK 52 52 T 0 0 0 12 47 LHHVVTTTTKA 53 53 T 0 0 0 12 25 MMMMVILLTMM 54 54 M 0 0 0 12 45 ALLLLNRVLCA 55 55 K 0 0 0 12 42 ENNTDEDKKQL 56 56 L 0 0 0 12 31 VAAIIVLLIIL 57 57 L 0 0 0 12 6 LLLFLLLILLL 58 58 T 0 0 0 12 40 RKQRNRKGRAQ 59 59 Q 0 0 0 12 36 GAAADHEGQAN 60 60 L 0 0 0 12 12 LLLFILILLIL 61 61 G 0 0 0 12 0 GGGGGGGGGGG 62 62 T 0 0 0 12 35 AVVGAAGIVVA 63 63 K 0 0 0 12 43 TKKSDDNTVNS 64 64 V 0 0 0 12 31 VYYVIVVMVLL 65 65 E 0 0 0 12 33 EEREAHHSDEE 66 66 R 0 0 0 12 40 lllrrffyrrw 67 67 N 0 0 0 7 38 .ddn...gt.p 68 68 G 0 0 0 12 40 dKRHnngEGdN 69 69 S 0 0 0 12 39 VTTETEETART 70 70 V 0 0 0 12 37 AVRYLVMVVLL 71 71 W 0 0 0 12 56 RCCMKTVILVQ 72 72 I 0 0 0 12 29 IVELIVVALVI 73 73 D 0 0 0 12 45 TVVHKNDNDDG 74 74 A 0 0 0 12 45 SEDLVAPTASA 75 75 S 0 0 0 12 41 PGGPLSTSSSK 76 76 N 0 0 0 12 50 DILQNYSTNNS 77 77 V 0 0 0 12 43 EGGLIAMLIVL 78 78 N 0 0 0 12 47 PGGQVLIDNGN 79 79 N 0 0 0 12 43 KAKTKQSNHHH 80 80 F 0 0 0 12 50 YFLCTTMQFGT 81 81 S 0 0 0 12 48 DKVEEEPFTPE 82 82 A 0 0 0 12 28 AVAVIALAAAA 83 83 P 0 0 0 12 33 DQEPDPPPPPT 84 84 Y 0 0 0 12 44 FNQCSFNYYYY 85 85 D 0 0 0 12 32 AGPESEGEEED 86 86 L 0 0 0 12 34 ALLAFYKLLLL 87 87 V 0 0 0 12 35 VSEATVVVVVV 88 88 K 0 0 0 12 46 RLLQDRKKKSR 89 89 T 0 0 0 12 52 QFFKLKKTTQK 90 90 M 0 0 0 12 16 FLLVIMLMMLM 91 91 R 0 0 0 12 26 RGGRRRRRRRR 92 92 A 0 0 0 12 19 ANNAAAAAAAA 93 93 S 0 0 0 12 16 SAASSSSSSSS 94 94 I 0 0 0 12 37 VGGIIVYIIFI 95 95 W 0 0 0 12 44 CTTLLLYLWFL 96 96 A 0 0 0 12 36 VAAFLVLVAVV 97 97 L 0 0 0 12 17 LMMALMMLLIL 98 98 G 0 0 0 12 29 GRRGGGGGAGG 99 99 P 0 0 0 12 6 PPPPPPAPPPP 100 100 L 0 0 0 12 3 LLLLFLMLLLL 101 101 V 0 0 0 12 29 VAALVLLLVLL 102 102 A 0 0 0 12 19 GAAASAGAASA 103 103 R 0 0 0 12 26 RAARRRRRRRR 104 104 F 0 0 0 12 35 CLLGFTFYFLF 105 105 G 0 0 0 12 47 KCCRGGKGHGK 106 106 Q 0 0 0 12 46 QLLKKHQSQME 107 107 G 0 0 0 12 38 AkgAIAAAGTC 108 108 Q 0 0 0 12 45 RqdVDRVKQKL 109 109 V 0 0 0 12 15 VIILMVIVVVV 110 110 S 0 0 0 12 41 AIVPAAGSSPS 111 111 L 0 0 0 12 12 LLLPLLLLLLL 112 112 P 0 0 0 12 17 PTTPPPPPPPP 113 113 G 0 0 0 12 0 GGGGGGGGGGG 114 114 G 0 0 0 12 14 GEEGGGGGGGG 115 115 C 0 0 0 12 43 DPPDDCCCCCC 116 116 A 0 0 0 12 45 ARRVVAHASAA 117 117 I 0 0 0 12 15 IMMIIILIIII 118 118 G 0 0 0 12 23 GKKGGGGGGGG 119 119 A 0 0 0 12 44 SEERKSPSATA 120 120 R 0 0 0 12 0 RRRRRRRRRRR 121 121 P 0 0 0 12 15 PPPRRPPPPPP 122 122 V 0 0 0 12 16 LIILLIIVVVV 123 123 D 0 0 0 12 15 DKGDDDDDDDD 124 124 L 0 0 0 12 46 MHHTTQQQLLL 125 125 H 0 0 0 12 24 HLLHHHHHHHH 126 126 I 0 0 0 12 29 QVVFFLILIVL 127 127 F 0 0 0 12 53 ADDLYKKKSRK 128 128 G 0 0 0 12 16 GAAAGGGAGGA 129 129 L 0 0 0 12 5 LLLLLFFLLLM 130 130 E 0 0 0 12 44 RRRACEEEEQQ 131 131 K 0 0 0 12 35 QQQAKAAAKAQ 132 132 L 0 0 0 12 21 LVGLLMLLLML 133 133 G 0 0 0 12 0 GGGGGGGGGGG 134 134 A 0 0 0 12 0 AAAAAAAAAAA 135 135 E 0 0 0 12 30 REQQKEEQDDK 136 136 I 0 0 0 12 18 CVIVLIVIIVI 137 137 K 0 0 0 12 46 NQDRSKTEVHT 138 138 L 0 0 0 12 41 IYYLTVNVLII 139 139 E 0 0 0 12 38 ELLDKGEEEEE 140 140 E 0 0 0 12 33 HEEGDNQAEHQ 141 141 G 0 0 0 11 29 GNQ.RGGGGGG 142 142 Y 0 0 0 12 54 CEEVRFAYYVY 143 143 V 0 0 0 12 34 VGNFIIIVVVI 144 144 K 0 0 0 12 54 VYYTVEYHKNH 145 145 A 0 0 0 12 43 APRFLALAAAA 146 146 S 0 0 0 12 39 SPRSKERKQSK 147 147 V 0 0 0 12 36 ALCAAVAVVIA 148 148 N 0 0 0 12 45 EAINNKEDSKp 149 149 G 0 0 0 8 37 Tia..G.GDg. 150 150 R 0 0 0 11 38 .ggKKRRRRrg 151 151 L 0 0 0 12 2 LLFLLLLLLLL 152 152 K 0 0 0 12 44 RQRVVQRKVTK 153 153 G 0 0 0 12 0 GGGGGGGGGGG 154 154 A 0 0 0 12 29 AGGCAAAGTAN 155 155 H 0 0 0 12 34 EKKDEKRERKD 156 156 I 0 0 0 12 15 IVLVMIIVIII 157 157 V 0 0 0 12 48 QQTFFYYIVYL 158 158 M 0 0 0 12 17 LIVLLLLFILF 159 159 D 0 0 0 12 5 EddDDDDDEDD 160 160 K 0 0 0 12 55 FssEEFVMKYK 161 161 V 0 0 0 12 35 PIVAAPVVVPI 162 162 S 0 0 0 12 7 SSSSSSSTSSS 163 163 V 0 0 0 12 23 VSSVVVVVVVV 164 164 G 0 0 0 12 33 GQQTTGGGGGT 165 165 A 0 0 0 12 35 AFFAAAAGAAG 166 166 T 0 0 0 12 23 TLLTTTTTTTT 167 167 V 0 0 0 12 38 ETTEEEIELEE 168 168 T 0 0 0 12 32 NAANNNNNSTN 169 169 I 0 0 0 12 21 ILLVILIIIIA 170 170 M 0 0 0 12 11 LLLLIIMLMLL 171 171 S 0 0 0 12 19 MMMMMMLTMMM 172 172 A 0 0 0 12 16 ASTAAAAAAAA 173 173 A 0 0 0 12 7 AAASAAAAAAA 174 174 T 0 0 0 12 39 VPPVVAVVTTS 175 175 L 0 0 0 12 4 VLLLLLLLLLL 176 176 A 0 0 0 12 0 AAAAAAAAAAA 177 177 E 0 0 0 12 13 EEEEEEEEKEK 178 178 G 0 0 0 12 16 GSQGGGGGGGG 179 179 T 0 0 0 12 45 VDDVNTKVTEI 180 180 T 0 0 0 12 11 TMTTTTTTTTT 181 181 I 0 0 0 12 43 TEEVVTITVVR 182 182 I 0 0 0 12 4 IIIIILIIIII 183 183 E 0 0 0 12 41 HEQTMEEREDI 184 184 N 0 0 0 12 26 NIINNNNNNNN 185 185 A 0 0 0 12 26 AiqAAVAAAAA 186 186 A 0 0 0 12 19 AvvAAAAAAAA 187 187 R 0 0 0 12 37 RSSSCKKRRRK 188 188 E 0 0 0 12 17 EKKEEEEEEEE 189 189 P 0 0 0 12 0 PPPPPPPPPPP 190 190 E 0 0 0 12 38 DYYHHEEEEEE 191 191 I 0 0 0 12 6 VIIVVIIIIII 192 192 V 0 0 0 12 44 VDDQQVITVVA 193 193 D 0 0 0 12 28 DIIDDDDDDDQ 194 194 T 0 0 0 12 33 LTTLLLVLTLL 195 195 A 0 0 0 12 42 CLLCCAAAAAC 196 196 N 0 0 0 12 43 TSHHNNTLDNA 197 197 F 0 0 0 12 18 MMLLMYLMFFF 198 198 L 0 0 0 12 19 LMMLLILLLCL 199 199 V 0 0 0 12 39 NNKNNNTINRQ 200 200 A 0 0 0 12 38 QDAASGSKKSS 201 201 L 0 0 0 12 24 MFFMMMMMMMG 202 202 G 0 0 0 12 0 GGGGGGGGGGG 203 203 A 0 0 0 12 28 AIVAAGAAAAV 204 204 K 0 0 0 12 36 QTDRNKKKKQE 205 205 I 0 0 0 12 8 VVVVIIIIIII 206 206 S 0 0 0 12 50 EEVSLRKETRH 207 207 G 0 0 0 12 20 GNHGGGGGGGG 208 208 Q 0 0 0 12 48 VREIIAALADI 209 209 G 0 0 0 12 16 GDNGGGGDGGG 210 210 T 0 0 0 12 41 SYYSSTTTSSS 211 211 D 0 0 0 12 40 PKQNNGNDASS 212 212 R 0 0 0 12 45 TTIVVTVTHRE 213 213 I 0 0 0 12 19 MFFLLIILIIL 214 214 T 0 0 0 12 48 TLHTEKRVTIK 215 215 I 0 0 0 12 5 IVIIIIIVIII 216 216 E 0 0 0 12 37 TKKEKEDTENR 217 217 G 0 0 0 12 0 GGGGGGGGGGG 218 218 V 0 0 0 12 22 VKGVVVVVVVV 219 219 E 0 0 0 12 34 PQQSKEKEEEE 220 220 R 0 0 0 12 44 RgtAKKESRKn 221 221 L 0 0 0 12 25 LasLLLLLLLl 222 222 G 0 0 0 12 45 YPPHSHHHTHN 223 223 G 0 0 0 11 33 PQ.GGGGGGSL 224 224 G 0 0 0 12 40 TGGTTVCCCTK 225 225 V 0 0 0 12 44 ENITVKKEEDD 226 226 Y 0 0 0 12 30 HYYYFHHYHFI 227 227 R 0 0 0 12 52 RLLTRHTSSPQ 228 228 V 0 0 0 12 11 VVVLIIIVVII 229 229 L 0 0 0 12 42 IEEGGIIVVII 230 230 P 0 0 0 12 28 GGGAAPPAPPP 231 231 D 0 0 0 12 0 DDDDDDDDDDD 232 232 R 0 0 0 12 45 RAAFFRRRRRR 233 233 I 0 0 0 12 32 ISSMMIIIIII 234 234 E 0 0 0 12 31 VSSEQEEEEEE 235 235 T 0 0 0 12 28 AAAVVAATTAA 236 236 G 0 0 0 12 20 ASSGGGGGGAG 237 237 T 0 0 0 12 40 TYYSSTTSTTT 238 238 F 0 0 0 12 8 WFFLLFFYFFY 239 239 L 0 0 0 12 21 GLLIIMMLLLL 240 240 V 0 0 0 12 41 IAAGSVIAICC 241 241 A 0 0 0 12 31 ASALLAAAAAV 242 242 A 0 0 0 12 14 AGAAAAGAAGG 243 243 A 0 0 0 12 9 AAAVAAAAAAA 244 244 I 0 0 0 12 19 MIIVLIAIIII 245 245 S 0 0 0 12 34 TKKTTTMTSTT 246 246 G 0 0 0 12 35 RGGRGEGGGHN 247 247 G 0 0 0 11 20 G.GGGGKGGSS 248 248 K 0 0 0 12 43 DKTAENEKCEQ 249 249 I 0 0 0 12 15 IVVLLVVVVIL 250 250 V 0 0 0 12 50 AKRTELIKVSK 251 251 C 0 0 0 12 28 VVVIIVITCLI 252 252 R 0 0 0 12 47 TTTSKKDTQFN 253 253 N 0 0 0 12 39 GGGDKGNHNPH 254 254 A 0 0 0 12 33 VIIVAAVTTVI 255 255 Q 0 0 0 12 46 DGGNDVIDKVI 256 256 P 0 0 0 12 31 PKKVPPPPAPP 257 257 D 0 0 0 12 39 AKQRQETNDDN 258 258 T 0 0 0 12 44 HSSDHHHLTHH 259 259 L 0 0 0 12 12 LIVLFLLLLLL 260 260 D 0 0 0 12 37 QQQRRTEEDAQ 261 261 A 0 0 0 12 41 LggPLSSSASA 262 262 V 0 0 0 12 28 VffLILLVVAI 263 263 L 0 0 0 12 48 LAAGRITLIIT 264 264 A 0 0 0 12 41 HDDFHAADDAD 265 265 K 0 0 0 12 36 KVVAVKKKKKK 266 266 L 0 0 0 12 12 LLLFYMLFLLL 267 267 R 0 0 0 12 42 HEEKSERERRI 268 268 E 0 0 0 12 29 DKKKREEEEEE 269 269 A 0 0 0 12 30 AMMLLMMMAII 270 270 G 0 0 0 12 0 GGGGGGGGGGG 271 271 A 0 0 0 12 40 AAAVIVYAAPF 272 272 D 0 0 0 12 46 TKKINTHEQES 273 273 I 0 0 0 12 26 VIIWFIIVVVL 274 274 E 0 0 0 12 38 TTSSEKETDAD 275 275 T 0 0 0 12 58 QWWEYDTRVII 276 276 G 0 0 0 12 35 TGGQDESGTDQ 277 277 E 0 0 0 12 26 DEDERGDEEAE 278 278 D 0 0 0 12 25 DDDHEEDDNPN 279 279 W 0 0 0 12 53 SFYANGQWSDS 280 280 I 0 0 0 12 25 FIIVVLLIIRI 281 281 S 0 0 0 12 53 RQESYRLETVE 282 282 L 0 0 0 12 39 VACVVVILLRI 283 283 D 0 0 0 12 50 AESSRIVDDLH 284 284 M 0 0 0 12 50 QQRANGGMMIP 285 285 H 0 0 0 11 54 YSGsk.GLLPA 286 286 G 0 0 0 10 40 E..ddPQGGRK 287 287 K 0 0 0 10 47 R..FFKKKNDK 288 288 R 0 0 0 12 48 PPEGGENRRLR 289 289 P 0 0 0 9 49 .LLGGLLPP.. 290 290 K 0 0 0 12 29 KKQMHKKKKRQ 291 291 A 0 0 0 12 37 AGGIIPPAAGA 292 292 V 0 0 0 12 33 VVIPPIVVVTF 293 293 T 0 0 0 12 33 NDDKKDDSNDE 294 294 V 0 0 0 12 21 VMMIIIVFIII 295 295 R 0 0 0 12 40 ADDDDKKRRET 296 296 T 0 0 0 12 35 TMMDDTTTTTT 297 297 A 0 0 0 12 50 LNNGGMLLALK 298 298 P 0 0 0 12 31 PHHPPPVPPPE 299 299 H 0 0 0 12 42 FIIWWHYHHYY 300 300 P 0 0 0 12 0 PPPPPPPPPPP 301 301 A 0 0 0 10 20 G..AAGGEGGG 302 302 F 0 0 0 10 0 F..FFFFFFFF 303 303 P 0 0 0 10 0 P..PPPPPPPP 304 304 T 0 0 0 10 10 T..PTTTTTTT 305 305 D 0 0 0 12 0 DDDDDDDDDDD 306 306 M 0 0 0 12 25 LAALLMLMMMM 307 307 Q 0 0 0 12 34 QAATMQQQQQQ 308 308 A 0 0 0 12 43 PMMSSSQAAAA 309 309 Q 0 0 0 12 46 MTTIIQPQQQQ 310 310 F 0 0 0 12 31 AIIMIMMIFFF 311 311 T 0 0 0 12 40 IAATVMTMTMM 312 312 L 0 0 0 12 37 ATTVVAAALAA 313 313 L 0 0 0 12 32 LTTVTLLVLLL 314 314 N 0 0 0 12 42 TAAAALLNNLA 315 315 L 0 0 0 12 42 SLLTTLTAMAT 316 316 V 0 0 0 12 51 IFFQQRRIVVQ 317 317 A 0 0 0 12 29 AAAVVAAGASC 318 318 E 0 0 0 12 34 DEDEESKREEL 319 319 G 0 0 0 12 0 GGGGGGGGGGG 320 320 T 0 0 0 10 30 T..VTTTFTNT 321 321 G 0 0 0 12 39 SEPIVSSASSS 322 322 V 0 0 0 12 34 MTTLLMVTIVV 323 323 I 0 0 0 12 8 IVVIVIVIIVI 324 324 T 0 0 0 12 43 TIIHFTTSTTE 325 325 E 0 0 0 12 24 ERREEEDEEEE 326 326 T 0 0 0 12 33 NNNKKTTTTTT 327 327 I 0 0 0 12 18 VIIMMVIIIVL 328 328 F 0 0 0 12 2 FYYFFFYFFFF 329 329 E 0 0 0 12 21 ENNEEESEEEE 330 330 N 0 0 0 12 44 AWWSSNANNNN 331 331 R 0 0 0 12 0 RRRRRRRRRRR 332 332 F 0 0 0 12 26 FVVMMFFFFLF 333 333 M 0 0 0 12 43 RKKFFMKMMQM 334 334 H 0 0 0 12 39 FEEFFHHHHHH 335 335 V 0 0 0 12 31 VTTVVAIVIVA 336 336 P 0 0 0 12 33 EDDDDEDPPAS 337 337 E 0 0 0 12 30 ERRKKEEEEEE 338 338 L 0 0 0 12 3 MLLLLFLLLLL 339 339 I 0 0 0 12 48 ITSIIRRAIQQ 340 340 R 0 0 0 12 35 RAATKRRRRRR 341 341 M 0 0 0 12 2 LMMMMMMMMML 342 342 G 0 0 0 12 17 GAAGGNGGGGG 343 343 A 0 0 0 12 22 ATTAAGAAGAA 344 344 H 0 0 0 12 36 DEERRDNNKNN 345 345 A 0 0 0 12 31 ALLIIIMIAII 346 346 E 0 0 0 12 45 RRRIVKKQEKS 347 347 I 0 0 0 12 39 TKKLLIVVILL 348 348 E 0 0 0 12 51 DVVCCEEEEKK 349 349 S 0 0 0 12 20 GGGddGGGGGT 350 350 N 0 0 0 10 30 H..hhRRNNNN 351 351 T 0 0 0 12 48 HAARRSSDTAV 352 352 V 0 0 0 12 33 AEEAVVAAAAA 353 353 I 0 0 0 12 22 VVVLVIIVVFT 354 354 C 0 0 0 12 39 VEEVVIIVCII 355 355 H 0 0 0 12 45 REESTNTTHQS 356 356 G 0 0 0 12 0 GGGGGGGGGGG 357 357 V 0 0 0 12 48 LEQPKPPVVVS 358 358 E 0 0 0 12 45 PDDSSVVEEPT 359 359 K 0 0 0 12 55 QFYASQEKQFE 360 360 L 0 0 0 12 10 LIILLLLLLLL 361 361 S 0 0 0 12 43 SRRHKQQSSST 362 362 G 0 0 0 12 29 SIVGGGGAGGG 363 363 A 0 0 0 12 38 AQVSNAAATAS 364 364 Q 0 0 0 12 39 PPPDVEKPEPD 365 365 V 0 0 0 12 21 VLPLLVVVVVV 366 366 M 0 0 0 12 48 WAAVSAKMIMM 367 367 A 0 0 0 12 39 CLQSSAAAASA 368 368 T 0 0 0 12 40 SelPPTSTTTT 369 369 D 0 0 0 12 7 DeeDDDDDDDD 370 370 L 0 0 0 12 17 IIIVVLLLLLL 371 371 R 0 0 0 12 24 REGRRRRRRRR 372 372 A 0 0 0 12 16 ATTAAAAAAAA 373 373 S 0 0 0 12 41 GYYGGGGSSSS 374 374 A 0 0 0 12 49 ANNMMASFIAS 375 375 S 0 0 0 12 35 GDDASACSSAA 376 376 L 0 0 0 12 25 LHHMLLLLLLL 377 377 V 0 0 0 12 31 VRRVLIVVVVV 378 378 L 0 0 0 12 14 LMMLILVLLIL 379 379 A 0 0 0 12 0 AAAAAAAAAAA 380 380 G 0 0 0 12 34 GMMAAGGAGGA 381 381 C 0 0 0 12 46 LCCCFLLLCLL 382 382 I 0 0 0 12 39 VFFCVVMAIAV 383 383 A 0 0 0 12 16 ASSAAAAAAAA 384 384 E 0 0 0 12 45 DLLREEDETEK 385 385 G 0 0 0 12 22 GIVGGGGGGGG 386 386 T 0 0 0 12 49 DAAVRHVEEKV 387 387 T 0 0 0 12 38 TLLSSTTTTTS 388 388 V 0 0 0 12 48 ESSIEREIIIR 389 389 V 0 0 0 12 30 VNDIIVIIVVV 390 390 D 0 0 0 12 46 YTTRQTTDDQH 391 391 R 0 0 0 12 43 DEPNNEGRRGR 392 392 I 0 0 0 12 15 VVVVVLLIILI 393 393 Y 0 0 0 12 48 FTTYYKEYYRY 394 394 H 0 0 0 12 33 HIIQQHHHHHH 395 395 I 0 0 0 12 14 ILLIILIIILL 396 396 D 0 0 0 12 6 DDDEEDDDDDD 397 397 R 0 0 0 12 17 RPPRRRRRRRR 398 398 G 0 0 0 10 0 G..GGGGGGGG 399 399 Y 0 0 0 10 0 Y..YYYYYYYY 400 400 E 0 0 0 12 35 PNKEEVSEEEE 401 401 R 0 0 0 12 53 LCCRDDSDHDR 402 402 I 0 0 0 12 33 FTTLVFLIIIL 403 403 E 0 0 0 12 41 VAAVVHEEEEE 404 404 D 0 0 0 12 36 EKKENQKADGD 405 405 K 0 0 0 12 27 NTTRKKKKKKK 406 406 L 0 0 0 12 8 LFFLLLLLLLI 407 407 R 0 0 0 12 47 APPQIAEQRRN 408 408 A 0 0 0 12 36 NTDANAGGGKA 409 409 L 0 0 0 12 21 LYYILLLLLLL 410 410 G 0 0 0 12 30 GFFGGGGGGGG 411 411 A 0 0 0 12 29 AREVAAAAAAA 412 412 N 0 0 0 12 36 EEQRKDTQKKK 413 413 I 0 0 0 11 15 LLIIIIIILV 414 414 E 0 0 0 10 52 EAW EWKETA 415 415 R 0 0 0 10 10 KRK RRRRRR 416 416 V 0 0 0 10 37 LLE VEVFIL 417 417 K 0 0 0 10 38 SSG nrSSEK 418 418 G 0 0 0 9 36 VQ qeEGQE 419 419 E 0 0 0 8 48 RI EE SPK ## SEQUENCE PROFILE AND ENTROPY SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT 1 1 0 8 0 75 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 12 0 0 0.837 34 1.00 2 2 0 0 0 0 0 0 0 0 0 0 8 8 0 8 0 0 0 42 0 33 12 0 0 1.352 54 1.00 3 3 8 0 0 0 8 0 0 0 0 0 17 0 8 0 8 50 0 0 0 0 12 0 0 1.474 59 1.00 4 4 0 33 17 0 33 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 1.330 54 1.00 5 5 17 0 17 0 0 0 0 0 0 0 0 17 0 0 25 0 0 17 8 0 12 0 0 1.748 70 1.00 6 6 50 17 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 1.011 41 1.00 7 7 8 0 0 0 0 0 8 0 8 0 0 17 0 8 8 0 17 25 0 0 12 0 0 1.979 80 1.00 8 8 0 0 0 0 0 0 0 83 0 17 0 0 0 0 0 0 0 0 0 0 12 0 0 0.451 18 1.00 9 9 0 0 17 0 0 0 0 50 0 8 0 0 0 0 8 0 17 0 0 0 12 0 0 1.358 55 1.00 10 10 17 0 0 0 8 0 8 0 17 0 17 8 0 0 0 0 8 0 8 8 12 0 0 2.138 86 1.00 11 11 0 8 0 0 0 0 0 0 0 17 17 0 0 0 33 25 0 0 0 0 12 0 0 1.517 61 1.00 12 12 17 67 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0.868 35 1.00 13 13 0 0 0 0 0 0 0 8 0 0 25 0 0 0 0 17 8 17 25 0 12 0 0 1.705 69 1.00 14 14 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0.000 0 1.00 15 15 0 0 0 0 0 0 0 0 0 0 8 25 8 0 0 0 8 50 0 0 12 0 0 1.314 53 1.00 16 16 75 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0.562 23 1.00 17 17 0 0 0 0 0 0 0 0 0 0 0 25 0 8 25 8 0 8 25 0 12 0 0 1.661 67 1.00 18 18 25 17 50 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 12 0 0 1.199 48 1.00 19 19 0 0 0 0 0 0 0 8 0 17 58 0 8 0 0 0 0 8 0 0 12 0 0 1.234 50 1.00 20 20 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0.000 0 1.00 21 21 0 0 0 0 0 0 0 0 67 0 17 0 0 0 0 0 0 0 17 0 12 0 0 0.868 35 1.00 22 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 12 0 0 0.000 0 1.00 23 23 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 83 0 12 0 0 0.451 18 1.00 24 24 8 8 0 0 0 0 0 0 50 0 33 0 0 0 0 0 0 0 0 0 12 0 0 1.127 45 1.00 25 25 17 0 0 0 0 0 0 0 67 0 17 0 0 0 0 0 0 0 0 0 12 0 0 0.868 35 1.00 26 26 8 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 12 0 0 0.721 29 1.00 27 27 0 0 0 0 0 0 0 0 17 58 0 0 0 0 17 8 0 0 0 0 12 0 0 1.119 45 1.00 28 28 8 25 33 0 0 0 0 0 17 0 0 0 17 0 0 0 0 0 0 0 12 0 0 1.517 61 1.00 29 29 0 50 33 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 1.011 41 1.00 30 30 0 25 0 0 17 0 0 0 50 8 0 0 0 0 0 0 0 0 0 0 12 0 0 1.199 48 1.00 31 31 0 17 0 0 0 0 0 8 75 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0.721 29 1.00 32 32 0 0 0 8 0 0 0 0 50 0 8 33 0 0 0 0 0 0 0 0 12 0 0 1.127 45 1.00 33 33 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100 0 0 0 0 0 0 0 0 0 0 0 0 10 2 0 0.000 0 1.00 399 399 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 10 2 0 0.000 0 1.00 400 400 8 0 0 0 0 0 0 0 0 8 8 0 0 0 0 8 0 58 8 0 12 0 0 1.350 54 1.00 401 401 0 8 0 0 0 0 0 0 0 0 8 0 17 8 25 0 0 0 0 33 12 0 0 1.633 66 1.00 402 402 8 25 33 0 17 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 12 0 0 1.517 61 1.00 403 403 25 0 0 0 0 0 0 0 17 0 0 0 0 8 0 0 0 50 0 0 12 0 0 1.199 48 1.00 404 404 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 25 8 17 8 25 12 0 0 1.820 73 1.00 405 405 0 0 0 0 0 0 0 0 0 0 0 17 0 0 8 67 0 0 8 0 12 0 0 0.983 40 1.00 406 406 0 75 8 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0.721 29 1.00 407 407 0 0 8 0 0 0 0 0 17 17 0 0 0 0 25 0 17 8 8 0 12 0 0 1.864 75 1.00 408 408 0 0 0 0 0 0 0 25 33 0 0 8 0 0 0 8 0 0 17 8 12 0 0 1.633 66 1.00 409 409 0 75 8 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0.721 29 1.00 410 410 0 0 0 0 17 0 0 83 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0.451 18 1.00 411 411 8 0 0 0 0 0 0 0 75 0 0 0 0 0 8 0 0 8 0 0 12 0 0 0.837 34 1.00 412 412 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 33 17 17 8 8 12 0 0 1.792 72 1.00 413 413 9 27 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0.860 36 1.00 414 414 0 0 0 0 0 20 0 0 20 0 0 10 0 0 0 10 0 40 0 0 10 0 0 1.471 64 1.00 415 415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 20 0 0 0 0 10 0 0 0.500 22 1.00 416 416 30 30 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 10 0 0 1.505 65 1.00 417 417 0 0 0 0 0 0 0 10 0 0 40 0 0 0 10 20 0 10 10 0 10 0 2 1.609 70 1.00 418 418 11 0 0 0 0 0 0 22 0 0 0 0 0 0 0 0 33 33 0 0 9 0 0 1.311 60 1.00 419 419 0 0 13 0 0 0 0 0 0 13 13 0 0 0 13 13 0 38 0 0 8 0 0 1.667 80 1.00 ## INSERTION LIST AliNo IPOS JPOS Len Sequence 1 66 66 2 lYGd 1 417 416 6 cLLLLCLl 2 66 66 2 lSDd 2 107 107 5 kGAETAq 2 149 149 3 iSNSg 2 159 159 1 dGs 2 185 185 3 iGDLv 2 220 220 2 gYVa 2 261 260 3 gDRLf 2 368 361 5 eNFQHAe 3 66 66 2 lSAd 3 107 107 2 gKNd 3 149 149 1 aGg 3 159 159 1 dGs 3 185 185 3 qGELv 3 220 220 2 tYRs 3 261 260 3 gDTKf 3 368 361 3 lIAAe 4 66 66 2 rRGn 4 285 283 7 sQDLRVNYd 4 349 347 1 dPh 5 66 66 2 rEGn 5 285 284 7 kQELKVKLd 5 349 348 1 dPh 5 417 416 6 kSQQQQSq 6 36 36 1 sEe 6 66 66 2 fENn 6 417 416 6 nDESASEq 7 66 66 2 fENg 7 417 416 3 rMTDe 8 66 66 1 yEg 9 66 66 2 rDAt 10 66 66 2 rDGd 10 149 149 3 gHSRr 11 66 66 2 wLNp 11 149 148 1 pKg 11 220 219 2 nDAl //