HSSP HOMOLOGY DERIVED SECONDARY STRUCTURE OF PROTEINS , VERSION 1.0 1991 PDBID 0_T0 DATE file generated on 11-Aug-98 SEQBASE temphssp PARAMETER CONVERTSEQ of 0_T0 THRESHOLD according to: ALL REFERENCE Sander C., Schneider R. : Database of homology-derived protein structures. Proteins, 9:56-68 (1991). CONTACT e-mail (INTERNET) Schneider@EMBL-Heidelberg.DE or Sander@EMBL-Heidelberg.DE / fax +49-6221-387306 AVAILABLE Free academic use. Commercial users must apply for license. AVAILABLE No inclusion in other databanks without permission. HEADER COMPND SOURCE AUTHOR SEQLENGTH 288 NCHAIN 1 chain(s) in 0_T0 data set NALIGN 9 NOTATION : ID: EMBL/SWISSPROT identifier of the aligned (homologous) protein NOTATION : STRID: if the 3-D structure of the aligned protein is known, then STRID is the Protein Data Bank identifier as taken NOTATION : from the database reference or DR-line of the EMBL/SWISSPROT entry NOTATION : %IDE: percentage of residue identity of the alignment NOTATION : %SIM (%WSIM): (weighted) similarity of the alignment NOTATION : IFIR/ILAS: first and last residue of the alignment in the test sequence NOTATION : JFIR/JLAS: first and last residue of the alignment in the alignend protein NOTATION : LALI: length of the alignment excluding insertions and deletions NOTATION : NGAP: number of insertions and deletions in the alignment NOTATION : LGAP: total length of all insertions and deletions NOTATION : LSEQ2: length of the entire sequence of the aligned protein NOTATION : ACCNUM: SwissProt accession number NOTATION : PROTEIN: one-line description of aligned protein NOTATION : SeqNo,PDBNo,AA,STRUCTURE,BP1,BP2,ACC: sequential and PDB residue numbers, amino acid (lower case = Cys), secondary NOTATION : structure, bridge partners, solvent exposure as in DSSP (Kabsch and Sander, Biopolymers 22, 2577-2637(1983) NOTATION : VAR: sequence variability on a scale of 0-100 as derived from the NALIGN alignments NOTATION : pair of lower case characters (AvaK) in the alignend sequence bracket a point of insertion in this sequence NOTATION : dots (....) in the alignend sequence indicate points of deletion in this sequence NOTATION : SEQUENCE PROFILE: relative frequency of an amino acid type at each position. Asx and Glx are in their NOTATION : acid/amide form in proportion to their database frequencies NOTATION : NOCC: number of aligned sequences spanning this position (including the test sequence) NOTATION : NDEL: number of sequences with a deletion in the test protein at this position NOTATION : NINS: number of sequences with an insertion in the test protein at this position NOTATION : ENTROPY: entropy measure of sequence variability at this position NOTATION : RELENT: relative entropy, i.e. entropy normalized to the range 0-100 NOTATION : WEIGHT: conservation weight ## PROTEINS : EMBL/SWISSPROT identifier and alignment statistics NR. ID STRID %IDE %SIM IFIR ILAS JFIR JLAS LALI NGAP LGAP LSEQ2 ACCNUM PROTEIN 1 : 1_HS 0.40 0.00 4 288 1 281 285 3 4 281 2 : 2_YJ 0.26 0.00 2 288 1 286 287 1 1 286 3 : 3_MT 0.29 0.00 4 288 1 279 285 3 6 279 4 : 4_TE 0.51 0.00 3 288 1 286 286 0 0 286 5 : 5_MT 0.43 0.00 8 288 1 268 281 7 13 268 6 : 6_CE 0.34 0.00 1 288 1 287 288 1 1 287 7 : 7_CE 0.36 0.00 1 288 1 287 288 1 1 287 8 : 8_CE 0.31 0.00 1 288 1 287 288 1 1 287 9 : 9_CE 0.27 0.00 3 281 1 252 279 2 27 252 ## ALIGNMENTS 1 - 9 SeqNo PDBNo AA STRUCTURE BP1 BP2 ACC NOCC VAR ....:....1....:....2....:....3....:....4....:....5....:....6....:....7 1 1 S 0 0 0 4 60 ETF 2 2 S 0 0 0 5 42 M SSK 3 3 M 0 0 0 7 41 S M RRKM 4 4 G 0 0 0 9 38 PAMS AAVA 5 5 Q 0 0 0 9 44 GSSD NDNL 6 6 A 0 0 0 9 41 DKDI DDNS 7 7 L 0 0 0 9 21 LMFL IIFV 8 8 K 0 0 0 10 44 RADNMKRQE 9 9 N 0 0 0 10 43 smENSaaee 10 10 L 0 0 0 10 34 vlLLIiiag 11 11 L 0 0 0 10 51 TELIEDDHR 12 12 T 0 0 0 10 40 TKAHETTKK 13 13 L 0 0 0 10 24 VIVLIFFFM 14 14 L 0 0 0 10 11 LLLLLLLFY 15 15 N 0 0 0 10 30 NEDKDNNDT 16 16 L 0 0 0 10 4 LLLLLLLFF 17 17 E 0 0 0 10 32 EVNEEQETE 18 18 K 0 0 0 10 40 PPAKQRREK 19 19 I 0 0 0 10 16 LLVILIVLI 20 20 E 0 0 0 10 30 DSADEDDKD 21 21 E 0 0 0 10 44 EPSDVTKKE 22 22 G 0 0 0 10 36 DTDLNNNDN 23 23 L 0 0 0 10 41 LSLIILLSN 24 24 F 0 0 0 10 2 FFFFYYYFF 25 25 R 0 0 0 10 46 RVTRRILSR 26 26 G 0 0 0 10 26 GTGGGAAPA 27 27 Q 0 0 0 9 41 RKSE.RRSD 28 28 S 0 0 0 10 46 HYHSSHHTY 29 29 E 0 0 0 10 43 YLPQVLLLL 30 30 D 0 0 0 10 54 WPSDFLLSF 31 31 L 0 0 0 10 52 VAKLSKKNH 32 32 G 0 0 0 10 30 PANGPGGGA 33 33 L 0 0 0 10 51 APPFERRRR 34 34 R 0 0 0 10 50 KVLRSHNQQ 35 35 Q 0 0 0 10 44 RgRQgssan 36 36 V 0 0 0 10 37 LtTVtvvaa 37 37 F 0 0 0 10 2 FFFFFYYYY 38 38 G 0 0 0 10 0 GGGGGGGGG 39 39 G 0 0 0 10 0 GGGGGGGGG 40 40 Q 0 0 0 10 36 QTQQHQQLL 41 41 V 0 0 0 10 16 ILLVVVVIL 42 42 V 0 0 0 10 32 VVMVAVIFF 43 43 G 0 0 0 10 24 GSAAGGGSS 44 44 Q 0 0 0 10 0 QQQQQQQQQ 45 45 A 0 0 0 10 22 ASSASSAAA 46 46 L 0 0 0 10 2 LLFLLLLLL 47 47 Y 0 0 0 10 44 VLVSVASAA 48 48 A 0 0 0 10 8 AAAASAAAA 49 49 A 0 0 0 10 16 ASSAAAAAA 50 50 K 0 0 0 10 49 ALSMVATEE 51 51 E 0 0 0 10 43 KHRQRAAKN 52 52 T 0 0 0 10 18 STTVTTTTT 53 53 V 0 0 0 10 15 VVLAVVVVV 54 54 P 0 0 0 10 39 SPtPDEEDS 55 55 E 0 0 0 10 41 ELhEPDVED 56 56 E 0 0 0 10 43 DNHDRCGQE 57 57 R 0 0 0 10 36 VFLRYFFFF 58 58 L 0 0 0 10 49 HFPIMIVKK 59 59 V 0 0 0 10 32 VPPLVPPPP 60 60 H 0 0 0 10 33 HTSHHHNHN 61 61 S 0 0 0 10 9 SSASSSSSS 62 62 F 0 0 0 10 25 LLFCLLLMI 63 63 H 0 0 0 10 14 HHSHHHHHH 64 64 S 0 0 0 10 32 CSVAGSSSA 65 65 Y 0 0 0 10 10 YYHYYYYYY 66 66 F 0 0 0 10 0 FFFFFFFFF 67 67 L 0 0 0 10 16 VIILLIVIV 68 68 R 0 0 0 10 45 RKNARKQLS 69 69 P 0 0 0 10 37 AGGPPTSNA 70 70 G 0 0 0 10 18 GGGGGGGVV 71 71 D 0 0 0 10 26 DDDDDSNDI 72 72 S 0 0 0 10 48 PPTSAVVTY 73 73 K 0 0 0 10 39 KRAQKDEKS 74 74 K 0 0 0 10 49 LTKYEKRET 75 75 P 0 0 0 10 27 PKDPRPPPP 76 76 I 0 0 0 10 22 VIIITIIIA 77 77 I 0 0 0 10 40 LTEIVLLSI 78 78 Y 0 0 0 10 1 YYFYFYYYY 79 79 D 0 0 0 10 42 QHQDLMQNK 80 80 V 0 0 0 10 3 VVVVVIVVV 81 81 E 0 0 0 10 37 EQIEEDDRK 82 82 T 0 0 0 10 30 RNRTRRRRR 83 83 L 0 0 0 10 22 TLLLIIIII 84 84 R 0 0 0 10 6 RRRRRRRRK 85 85 D 0 0 0 10 18 TNDEDDDDD 86 86 G 0 0 0 10 8 GGEGGGGGG 87 87 N 0 0 0 10 33 SRRRGRKRK 88 88 S 0 0 0 10 32 SNRNSSSST 89 89 F 0 0 0 10 0 FFFFFFFFF 90 90 S 0 0 0 10 38 SIASCCCII 91 91 A 0 0 0 10 43 VHNATTTTI 92 92 R 0 0 0 10 19 RKRLRRRRR 93 93 R 0 0 0 10 53 SQRCRVLTT 94 94 V 0 0 0 10 0 VVVVVVVVV 95 95 A 0 0 0 10 38 KSDKNKKEE 96 96 A 0 0 0 10 0 AAAAAAAAA 97 97 I 0 0 0 10 21 VYVIVVLVV 98 98 Q 0 0 0 10 0 QQQQQQQQQ 99 99 N 0 0 0 10 31 HHDHHDDKN 100 100 G 0 0 0 10 23 GDGKGGGDD 101 101 K 0 0 0 10 35 KKTNEEEKR 102 102 P 0 0 0 10 45 PLLTTAAVI 103 103 I 0 0 0 10 24 IILIIIICC 104 104 F 0 0 0 10 24 FFSCFFFFF 105 105 Y 0 0 0 10 49 ITSHSSTVV 106 106 M 0 0 0 10 45 CSAVMCVLL 107 107 T 0 0 0 10 42 QMMTAQQQQ 108 108 A 0 0 0 10 35 AIVAAIICV 109 109 S 0 0 0 10 15 SLSSSSSSS 110 110 F 0 0 0 10 1 FFYFFFFFF 111 111 Q 0 0 0 10 34 QaMQQhHHH 112 112 A 0 0 0 8 51 Qs.V.qRVI 113 113 P 0 0 0 10 41 AKAPTKPES 114 114 E 0 0 0 10 13 QEGEEEEEE 115 115 A 0 0 0 10 44 phgKqpakk 116 116 G 0 0 0 10 25 psgGgassg 117 117 F 0 0 0 10 31 MLHFIIIIM 118 118 E 0 0 0 10 45 QQEETKVII 119 119 H 0 0 0 10 0 HHHHHHHHH 120 120 Q 0 0 0 10 33 QWAQQSQQQ 121 121 K 0 0 0 10 52 FELNDSLSD 122 122 T 0 0 0 10 46 STDTVKPEI 123 123 M 0 0 0 10 20 MIPMMMMMM 124 124 P 0 0 0 10 0 PPPPPPPPP 125 125 S 0 0 0 10 43 TGQNAEEKK 126 126 A 0 0 0 10 22 VLVVAVVVV 127 127 P 0 0 0 10 29 PqAGPTPPP 128 128 A 0 0 0 10 38 PqEAPPAEN 129 129 P 0 0 0 10 0 PPPPPPPPP 130 130 D 0 0 0 10 17 EdHEDEDEE 131 131 G 0 0 0 10 41 EsTDGQSVS 132 132 L 0 0 0 10 17 LLRFLLLLL 133 133 P 0 0 0 10 48 LSPTPLEMM 134 134 S 0 0 0 10 34 DDPDGPDSS 135 135 E 0 0 0 10 51 CRIELALMM 136 136 T 0 0 0 10 51 EFGNNRSRK 137 137 Q 0 0 0 10 38 TQEVSEDDD 138 138 I 0 0 0 10 45 LDLMIATAA 139 139 A 0 0 0 10 42 IALLKAFVV 140 140 Q 0 0 0 10 51 DTRQVLEPI 141 141 S 0 0 0 10 52 QSGKFERYS 142 142 L 0 0 0 10 46 YMYVDVIMT 143 143 A 0 0 0 10 49 LSEADLKKK 144 144 H 0 0 0 10 39 RKEQARKEK 145 145 L 0 0 0 10 50 DYTTGTNLL 146 146 L 0 0 0 10 40 PVVLFKAVV 147 147 P 0 0 0 10 40 NdPPRenen 148 148 P 0 0 0 7 48 .y.E.vaaa 149 149 V 0 0 0 10 49 LQHPQTAMM 150 150 L 0 0 0 10 28 QFFLFALLL 151 151 K 0 0 0 10 48 KPVNDGAAH 152 152 D 0 0 0 10 46 RKNEEVMRR 153 153 K 0 0 0 10 54 YDAKWIILL 154 154 F 0 0 0 10 52 PMLFDQGQM 155 155 I 0 0 0 10 49 LFQAVHFSV 156 156 C 0 0 0 10 51 AYPACFKYL 157 157 D 0 0 0 10 48 LSIEILQDD 158 158 R 0 0 0 10 47 naeRvkksn 159 159 P 0 0 0 8 46 pf.P.vilm 160 160 L 0 0 0 8 19 IV.F.FFFF 161 161 E 0 0 0 8 25 EK.E.DSEE 162 162 V 0 0 0 8 31 IV.V.VFMA 163 163 R 0 0 0 10 5 KRrRrRRRR 164 164 P 0 0 0 10 43 PPYTEPPCC 165 165 V 0 0 0 10 45 VPAKRVVTT 166 166 E 0 0 0 9 37 NINY.NDNN 167 167 F 0 0 0 9 49 PTDL.PILL 168 168 H 0 0 0 10 48 STPNLADGG 169 169 N 0 0 0 10 45 PVANRKSNN 170 170 P 0 0 0 10 52 LEWPLYYYW 171 171 L 0 0 0 10 39 SHIFLLLYY 172 172 K 0 0 0 10 53 QAMNPLCGG 173 173 G 0 0 0 10 56 LGRGGKLFY 174 174 H 0 0 0 10 47 QDDTKEKAC 175 175 V 0 0 0 10 45 REKKADKSS 176 176 A 0 0 0 10 47 msgLSTddd 177 177 E 0 0 0 9 51 pllP.Eakk 178 178 P 0 0 0 8 43 .HAA.PYPH 179 179 H 0 0 0 10 46 KKYEQMREQ 180 180 R 0 0 0 10 47 QHNQQSSLA 181 181 Q 0 0 0 10 50 MHRYQMYYR 182 182 V 0 0 0 10 37 FPVSVIVFV 183 183 W 0 0 0 10 3 WYWWWWWWW 184 184 I 0 0 0 10 33 VRVFLIIMM 185 185 R 0 0 0 10 25 RIKKRRKRR 186 186 A 0 0 0 10 30 APATHAAAT 187 187 N 0 0 0 10 38 RKLNRRNRR 188 188 G 0 0 0 10 25 GSGGDEEGE 189 189 S 0 0 0 10 51 YIEEPNNDR 190 190 V 0 0 0 10 30 ITMTLLILL 191 191 P 0 0 0 10 32 GPPPPGGSN 192 192 D 0 0 0 10 32 eeDLDDDNt 193 193 D 0 0 0 10 0 ddDDDDDDd 194 194 L 0 0 0 10 50 MAPIPHPEK 195 195 R 0 0 0 10 31 KRVKVRRRR 196 196 V 0 0 0 10 22 MYLILLLFL 197 197 H 0 0 0 10 13 HNHQHHHHH 198 198 Q 0 0 0 10 55 CYTQIQLRR 199 199 Y 0 0 0 10 52 CVACCCAWW 200 200 L 0 0 0 10 38 VATLAVALL 201 201 L 0 0 0 10 33 AFLLLAAIL 202 202 G 0 0 0 10 18 AALAAAAAA 203 203 Y 0 0 0 10 4 YYYYYYYYC 204 204 A 0 0 0 10 42 ILSFMLINM 205 205 S 0 0 0 10 8 SSSSSTSSS 206 206 D 0 0 0 10 0 DDDDDDDDD 207 207 L 0 0 0 10 48 YSTFLLASA 208 208 N 0 0 0 10 51 AYTHTSTLI 209 209 F 0 0 0 10 28 FLVCLMMLL 210 210 L 0 0 0 10 12 LLLILLIVL 211 211 P 0 0 0 10 49 GLDLGTESP 212 212 V 0 0 0 10 30 TTSTSTTTA 213 213 A 0 0 0 10 26 AIVAAAAAG 214 214 L 0 0 0 10 34 LPILQVLVM 215 215 Q 0 0 0 10 56 LYTHVRRSS 216 216 P 0 0 0 10 39 PFTPNPPPA 217 217 H 0 0 0 10 0 HHHHHHHHH 218 218 G 0 0 0 10 55 QNGELISYF 219 219 I 0 0 0 10 52 WLLKDRKTS 220 220 G 0 0 0 9 45 QPSG.NRTA 221 221 F 0 0 0 9 55 HLWF.GGGT 222 222 L 0 0 0 10 43 KYGLVFFFV 223 223 E 0 0 0 10 54 VCFQRIICT 224 224 P 0 0 0 10 46 HHDKDPPSV 225 225 G 0 0 0 10 44 FSRGQSSSA 226 226 I 0 0 0 10 30 MFIMLMMMN 227 227 Q 0 0 0 10 54 VSFKQSALT 228 228 I 0 0 0 10 45 SVAVVFLFE 229 229 A 0 0 0 8 28 .SAAASTS. 230 230 T 0 0 0 4 31 ..STS.... 231 231 I 0 0 0 9 23 LLAILLLL. 232 232 D 0 0 0 9 7 DDNDDDDD. 233 233 H 0 0 0 9 0 HHHHHHHH. 234 234 S 0 0 0 9 27 STSSACSC. 235 235 M 0 0 0 9 20 MIVIMIIV. 236 236 W 0 0 0 9 4 WYWWWWWW. 237 237 F 0 0 0 9 14 FFFFFMMF. 238 238 H 0 0 0 9 15 HHHHMhhh. 239 239 R 0 0 0 10 41 AQRRRndsK 240 240 P 0 0 0 10 43 PLQPPENEE 241 241 F 0 0 0 10 41 FPVFFFFVS 242 242 N 0 0 0 10 42 RHNDRRRKV 243 243 L 0 0 0 10 36 AVFLAIVAL 244 244 N 0 0 0 10 28 DNDNDDDDL 245 245 E 0 0 0 10 35 HNDHEDDEL 246 246 W 0 0 0 10 1 WWWWWWWWR 247 247 L 0 0 0 10 25 MIVHLMMLL 248 248 L 0 0 0 10 17 LYLLLLLLY 249 249 Y 0 0 0 10 28 YLYHYYYFN 250 250 S 0 0 0 10 43 EKSADEEEY 251 251 V 0 0 0 10 47 CITIQTNCC 252 252 E 0 0 0 10 46 ESSESIHKI 253 253 S 0 0 0 10 21 SNSSSSSSI 254 254 T 0 0 0 10 41 PPPNPSTRV 255 255 S 0 0 0 10 50 WRVNSKIII 256 256 A 0 0 0 10 20 ASAAAAAAI 257 257 S 0 0 0 10 44 GHAFSGGSN 258 258 S 0 0 0 9 33 GWDGGGGG. 259 259 A 0 0 0 9 27 SDSGGSGS. 260 260 R 0 0 0 9 6 RKRRRRRR. 261 261 G 0 0 0 9 32 GHGGAASA. 262 262 F 0 0 0 9 17 LLLLLFLT. 263 263 V 0 0 0 9 34 VVGATIII. 264 264 R 0 0 0 9 39 HQSQREEE. 265 265 G 0 0 0 9 0 GGGGGGGG. 266 266 E 0 0 0 9 35 RKHQERKR. 267 267 F 0 0 0 9 25 VYFIILLI. 268 268 Y 0 0 0 9 5 WfFFFWWW. 269 269 T 0 0 0 9 37 StDSTSTR. 270 270 Q 0 0 0 9 23 QQRQRRRR. 271 271 D 0 0 0 9 25 DSSDSDDD. 272 272 G 0 0 0 9 0 GGGGGGGG. 273 273 V 0 0 0 9 46 VRKQERRV. 274 274 L 0 0 0 9 8 LILLMLLL. 275 275 V 0 0 0 10 22 AMIIVIVII 276 276 A 0 0 0 10 37 VAAAAIFAY 277 277 S 0 0 0 10 32 TSTTASSSK 278 278 T 0 0 0 10 36 CVVTVTTCC 279 279 V 0 0 0 10 51 ASVQMATQF 280 280 Q 0 0 0 10 6 QQQQQQQQH 281 281 E 0 0 0 10 17 EEEEEEEEF 282 282 G 0 0 0 9 15 GGGGGAAA 283 283 V 0 0 0 9 23 VYVLLLLL 284 284 M 0 0 0 9 25 IVLITVIV 285 285 R 0 0 0 9 22 RVKRRRRR 286 286 N 0 0 0 9 53 VYYFHATS 287 287 H 0 0 0 9 54 KGFSRPAK 288 288 N 0 0 0 9 43 PSPERKKS ## SEQUENCE PROFILE AND ENTROPY SeqNo PDBNo V L I M F W Y G A P S T C H R K Q E N D NOCC NDEL NINS ENTROPY RELENT WEIGHT 1 1 0 0 0 0 25 0 0 0 0 0 25 25 0 0 0 0 0 25 0 0 4 0 0 1.386 100 1.00 2 2 0 0 0 20 0 0 0 0 0 0 60 0 0 0 0 20 0 0 0 0 5 0 0 0.950 59 1.00 3 3 0 0 0 43 0 0 0 0 0 0 14 0 0 0 29 14 0 0 0 0 7 0 0 1.277 66 1.00 4 4 11 0 0 11 0 0 0 11 44 11 11 0 0 0 0 0 0 0 0 0 9 0 0 1.581 72 1.00 5 5 0 11 0 0 0 0 0 11 0 0 22 0 0 0 0 0 11 0 22 22 9 0 0 1.735 79 1.00 6 6 0 0 11 0 0 0 0 0 11 0 11 0 0 0 0 11 0 0 11 44 9 0 0 1.581 72 1.00 7 7 11 33 22 11 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 1.523 69 1.00 8 8 0 0 0 10 0 0 0 0 10 0 0 0 0 0 20 20 10 10 10 10 10 0 0 2.025 88 1.00 9 9 0 0 0 10 0 0 0 0 20 0 20 0 0 0 0 0 0 30 20 0 10 0 6 1.557 68 1.00 10 10 10 40 30 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 1.418 62 1.00 11 11 0 20 10 0 0 0 0 0 0 0 0 10 0 10 10 0 0 20 0 20 10 0 0 1.887 82 1.00 12 12 0 0 0 0 0 0 0 0 10 0 0 40 0 10 0 30 0 10 0 0 10 0 0 1.418 62 1.00 13 13 20 20 20 10 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 1.557 68 1.00 14 14 0 80 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.639 28 1.00 15 15 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 10 40 30 10 0 0 1.418 62 1.00 16 16 0 80 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.500 22 1.00 17 17 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 60 10 0 10 0 0 1.228 53 1.00 18 18 0 0 0 0 0 0 0 0 10 20 0 0 0 0 20 30 10 10 0 0 10 0 0 1.696 74 1.00 19 19 20 40 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 1.055 46 1.00 20 20 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 10 0 20 0 50 10 0 0 1.359 59 1.00 21 21 10 0 0 0 0 0 0 0 0 10 10 10 0 0 0 20 0 30 0 10 10 0 0 1.834 80 1.00 22 22 0 10 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 40 30 10 0 0 1.418 62 1.00 23 23 0 50 20 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 10 0 10 0 0 1.221 53 1.00 24 24 0 0 0 0 70 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.611 27 1.00 25 25 10 10 10 0 0 0 0 0 0 0 10 10 0 0 50 0 0 0 0 0 10 0 0 1.498 65 1.00 26 26 0 0 0 0 0 0 0 50 30 10 0 10 0 0 0 0 0 0 0 0 10 0 0 1.168 51 1.00 27 27 0 0 0 0 0 0 0 0 0 0 22 0 0 0 33 11 11 11 0 11 9 1 0 1.677 76 1.00 28 28 0 0 0 0 0 0 20 0 0 0 30 10 0 40 0 0 0 0 0 0 10 0 0 1.280 56 1.00 29 29 10 50 0 0 0 0 10 0 0 10 0 0 0 0 0 0 10 10 0 0 10 0 0 1.498 65 1.00 30 30 0 20 0 0 20 10 0 0 0 10 20 0 0 0 0 0 0 0 0 20 10 0 0 1.748 76 1.00 31 31 10 20 0 0 0 0 0 0 10 0 10 0 0 10 0 30 0 0 10 0 10 0 0 1.834 80 1.00 32 32 0 0 0 0 0 0 0 50 20 20 0 0 0 0 0 0 0 0 10 0 10 0 0 1.221 53 1.00 33 33 0 10 0 0 10 0 0 0 10 20 0 0 0 0 40 0 0 10 0 0 10 0 0 1.609 70 1.00 34 34 10 10 0 0 0 0 0 0 0 0 10 0 0 10 20 10 20 0 10 0 10 0 0 2.025 88 1.00 35 35 0 0 0 0 0 0 0 20 10 0 20 0 0 0 20 0 20 0 10 0 10 0 6 1.748 76 1.00 36 36 40 10 0 0 0 0 0 0 20 0 0 30 0 0 0 0 0 0 0 0 10 0 0 1.280 56 1.00 37 37 0 0 0 0 60 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.673 29 1.00 38 38 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.000 0 1.00 39 39 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.000 0 1.00 40 40 0 20 0 0 0 0 0 0 0 0 0 10 0 10 0 0 60 0 0 0 10 0 0 1.089 47 1.00 41 41 50 30 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 1.030 45 1.00 42 42 50 0 10 10 20 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 1.359 59 1.00 43 43 0 0 0 0 0 0 0 50 20 0 30 0 0 0 0 0 0 0 0 0 10 0 0 1.030 45 1.00 44 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 10 0 0 0.000 0 1.00 45 45 0 0 0 0 0 0 0 0 60 0 40 0 0 0 0 0 0 0 0 0 10 0 0 0.673 29 1.00 46 46 0 90 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.325 14 1.00 47 47 30 10 0 0 0 0 10 0 30 0 20 0 0 0 0 0 0 0 0 0 10 0 0 1.505 65 1.00 48 48 0 0 0 0 0 0 0 0 90 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0.325 14 1.00 49 49 0 0 0 0 0 0 0 0 80 0 20 0 0 0 0 0 0 0 0 0 10 0 0 0.500 22 1.00 50 50 10 10 0 10 0 0 0 0 20 0 10 10 0 0 0 10 0 20 0 0 10 0 0 2.025 88 1.00 51 51 0 0 0 0 0 0 0 0 20 0 0 0 0 10 20 20 10 10 10 0 10 0 0 1.887 82 1.00 52 52 10 0 0 0 0 0 0 0 0 0 10 80 0 0 0 0 0 0 0 0 10 0 0 0.639 28 1.00 53 53 80 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.639 28 1.00 54 54 0 0 0 0 0 0 0 0 0 30 20 10 0 0 0 0 0 20 0 20 10 0 1 1.557 68 1.00 55 55 10 10 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 40 0 20 10 0 0 1.609 70 1.00 56 56 0 0 0 0 0 0 0 10 0 0 0 0 10 10 10 0 10 20 10 20 10 0 0 2.025 88 1.00 57 57 10 10 0 0 50 0 10 0 0 0 0 0 0 0 20 0 0 0 0 0 10 0 0 1.359 59 1.00 58 58 10 10 20 10 10 0 0 0 0 10 0 0 0 10 0 20 0 0 0 0 10 0 0 2.025 88 1.00 59 59 30 10 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 10 0 0 0.898 39 1.00 60 60 0 0 0 0 0 0 0 0 0 0 10 10 0 60 0 0 0 0 20 0 10 0 0 1.089 47 1.00 61 61 0 0 0 0 0 0 0 0 10 0 90 0 0 0 0 0 0 0 0 0 10 0 0 0.325 14 1.00 62 62 0 50 10 10 20 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 1.359 59 1.00 63 63 0 0 0 0 0 0 0 0 0 0 10 0 0 90 0 0 0 0 0 0 10 0 0 0.325 14 1.00 64 64 10 0 0 0 0 0 0 10 20 0 50 0 10 0 0 0 0 0 0 0 10 0 0 1.359 59 1.00 65 65 0 0 0 0 0 0 90 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0.325 14 1.00 66 66 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.000 0 1.00 67 67 30 30 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 1.089 47 1.00 68 68 0 10 0 0 0 0 0 0 10 0 10 0 0 0 30 20 10 0 10 0 10 0 0 1.834 80 1.00 69 69 0 0 0 0 0 0 0 20 20 30 10 10 0 0 0 0 0 0 10 0 10 0 0 1.696 74 1.00 70 70 20 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.500 22 1.00 71 71 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 70 10 0 0 0.940 41 1.00 72 72 20 0 0 0 0 0 10 0 10 20 20 20 0 0 0 0 0 0 0 0 10 0 0 1.748 76 1.00 73 73 0 0 0 0 0 0 0 0 10 0 10 0 0 0 10 40 10 10 0 10 10 0 0 1.748 76 1.00 74 74 0 10 0 0 0 0 10 0 0 0 0 20 0 0 10 30 0 20 0 0 10 0 0 1.696 74 1.00 75 75 0 0 0 0 0 0 0 0 0 70 0 0 0 0 10 10 0 0 0 10 10 0 0 0.940 41 1.00 76 76 10 0 70 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0.940 41 1.00 77 77 10 30 30 0 0 0 0 0 0 0 10 10 0 0 0 0 0 10 0 0 10 0 0 1.643 71 1.00 78 78 0 0 0 0 20 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.500 22 1.00 79 79 0 10 0 10 0 0 0 0 0 0 0 0 0 10 0 10 30 0 10 20 10 0 0 1.834 80 1.00 80 80 90 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.325 14 1.00 81 81 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 10 10 40 0 20 10 0 0 1.609 70 1.00 82 82 0 0 0 0 0 0 0 0 0 0 0 20 0 0 70 0 0 0 10 0 10 0 0 0.802 35 1.00 83 83 0 40 50 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0.943 41 1.00 84 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90 10 0 0 0 0 10 0 0 0.325 14 1.00 85 85 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 10 70 10 0 0 0.940 41 1.00 86 86 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0.325 14 1.00 87 87 0 0 0 0 0 0 0 10 0 0 10 0 0 0 50 20 0 0 10 0 10 0 0 1.359 59 1.00 88 88 0 0 0 0 0 0 0 0 0 0 60 10 0 0 10 0 0 0 20 0 10 0 0 1.089 47 1.00 89 89 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.000 0 1.00 90 90 0 0 30 0 0 0 0 0 10 0 30 0 30 0 0 0 0 0 0 0 10 0 0 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0.639 28 1.00 105 105 20 0 10 0 0 0 10 0 0 0 30 20 0 10 0 0 0 0 0 0 10 0 0 1.696 74 1.00 106 106 20 20 0 20 0 0 0 0 10 0 10 0 20 0 0 0 0 0 0 0 10 0 0 1.748 76 1.00 107 107 0 0 0 20 0 0 0 0 10 0 0 20 0 0 0 0 50 0 0 0 10 0 0 1.221 53 1.00 108 108 20 0 30 0 0 0 0 0 40 0 0 0 10 0 0 0 0 0 0 0 10 0 0 1.280 56 1.00 109 109 0 10 0 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 10 0 0 0.325 14 1.00 110 110 0 0 0 0 90 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.325 14 1.00 111 111 0 0 0 10 0 0 0 0 10 0 0 0 0 40 0 0 40 0 0 0 10 0 2 1.194 52 1.00 112 112 25 0 13 0 0 0 0 0 13 0 13 0 0 0 13 0 25 0 0 0 8 2 0 1.733 83 1.00 113 113 0 0 0 0 0 0 0 0 20 30 10 10 0 0 0 20 0 10 0 0 10 0 0 1.696 74 1.00 114 114 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 10 80 0 0 10 0 0 0.639 28 1.00 115 115 0 0 0 0 0 0 0 10 20 20 0 0 0 10 0 30 10 0 0 0 10 0 8 1.696 74 1.00 116 116 0 0 0 0 0 0 0 50 10 10 30 0 0 0 0 0 0 0 0 0 10 0 0 1.168 51 1.00 117 117 0 10 40 20 20 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 1.471 64 1.00 118 118 10 0 20 0 0 0 0 0 0 0 0 10 0 0 0 10 20 30 0 0 10 0 0 1.696 74 1.00 119 119 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 10 0 0 0.000 0 1.00 120 120 0 0 0 0 0 10 0 0 10 0 10 0 0 0 0 0 70 0 0 0 10 0 0 0.940 41 1.00 121 121 0 20 0 0 10 0 0 0 0 0 20 0 0 0 0 10 0 10 10 20 10 0 0 1.887 82 1.00 122 122 10 0 10 0 0 0 0 0 0 10 10 30 0 0 0 10 0 10 0 10 10 0 0 1.973 86 1.00 123 123 0 0 10 80 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0.639 28 1.00 124 124 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 10 0 0 0.000 0 1.00 125 125 0 0 0 0 0 0 0 10 10 0 10 10 0 0 0 20 10 20 10 0 10 0 0 2.025 88 1.00 126 126 70 10 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0.802 35 1.00 127 127 0 0 0 0 0 0 0 10 10 60 0 10 0 0 0 0 10 0 0 0 10 0 1 1.228 53 1.00 128 128 0 0 0 0 0 0 0 0 30 30 0 0 0 0 0 0 10 20 10 0 10 0 0 1.505 65 1.00 129 129 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 10 0 0 0.000 0 1.00 130 130 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 50 0 40 10 0 1 0.943 41 1.00 131 131 10 0 0 0 0 0 0 20 0 0 30 10 0 0 0 0 10 10 0 10 10 0 0 1.834 80 1.00 132 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0 0 0 0 0 10 0 10 0 0 0.639 28 1.00 254 254 10 0 0 0 0 0 0 0 0 40 10 20 0 0 10 0 0 0 10 0 10 0 0 1.609 70 1.00 255 255 10 0 30 0 0 10 0 0 0 0 20 0 0 0 10 10 0 0 10 0 10 0 0 1.834 80 1.00 256 256 0 0 10 0 0 0 0 0 80 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0.639 28 1.00 257 257 0 0 0 0 10 0 0 30 10 0 30 0 0 10 0 0 0 0 10 0 10 0 0 1.643 71 1.00 258 258 0 0 0 0 0 11 0 67 0 0 11 0 0 0 0 0 0 0 0 11 9 1 0 1.003 46 1.00 259 259 0 0 0 0 0 0 0 33 11 0 44 0 0 0 0 0 0 0 0 11 9 1 0 1.215 55 1.00 260 260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89 11 0 0 0 0 9 1 0 0.349 16 1.00 261 261 0 0 0 0 0 0 0 44 33 0 11 0 0 11 0 0 0 0 0 0 9 1 0 1.215 55 1.00 262 262 0 67 0 0 22 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 9 1 0 0.849 39 1.00 263 263 33 0 33 0 0 0 0 11 11 0 0 11 0 0 0 0 0 0 0 0 9 1 0 1.465 67 1.00 264 264 0 0 0 0 0 0 0 0 0 0 11 0 0 11 22 0 22 33 0 0 9 1 0 1.523 69 1.00 265 265 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 9 1 0 0.000 0 1.00 266 266 0 0 0 0 0 0 0 0 0 0 0 0 0 11 33 22 11 22 0 0 9 1 0 1.523 69 1.00 267 267 11 22 33 0 22 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 9 1 0 1.523 69 1.00 268 268 0 0 0 0 44 44 11 0 0 0 0 0 0 0 0 0 0 0 0 0 9 1 1 0.965 44 1.00 269 269 0 0 0 0 0 0 0 0 0 0 33 44 0 0 11 0 0 0 0 11 9 1 0 1.215 55 1.00 270 270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 0 44 0 0 0 9 1 0 0.687 31 1.00 271 271 0 0 0 0 0 0 0 0 0 0 33 0 0 0 0 0 0 0 0 67 9 1 0 0.637 29 1.00 272 272 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 9 1 0 0.000 0 1.00 273 273 33 0 0 0 0 0 0 0 0 0 0 0 0 0 33 11 11 11 0 0 9 1 0 1.465 67 1.00 274 274 0 78 11 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 1 0 0.684 31 1.00 275 275 30 0 50 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 1.168 51 1.00 276 276 10 0 10 0 10 0 10 0 60 0 0 0 0 0 0 0 0 0 0 0 10 0 0 1.228 53 1.00 277 277 0 0 0 0 0 0 0 0 10 0 50 30 0 0 0 10 0 0 0 0 10 0 0 1.168 51 1.00 278 278 30 0 0 0 0 0 0 0 0 0 0 40 30 0 0 0 0 0 0 0 10 0 0 1.089 47 1.00 279 279 20 0 0 10 10 0 0 0 20 0 10 10 0 0 0 0 20 0 0 0 10 0 0 1.887 82 1.00 280 280 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 90 0 0 0 10 0 0 0.325 14 1.00 281 281 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 90 0 0 10 0 0 0.325 14 1.00 282 282 0 0 0 0 0 0 0 67 33 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0.637 29 1.00 283 283 33 56 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0.937 43 1.00 284 284 33 11 33 11 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 9 0 0 1.465 67 1.00 285 285 11 0 0 0 0 0 0 0 0 0 0 0 0 0 78 11 0 0 0 0 9 0 0 0.684 31 1.00 286 286 11 0 0 0 11 0 22 0 11 0 11 11 0 11 0 0 0 0 11 0 9 0 0 2.043 93 1.00 287 287 0 0 0 0 11 0 0 11 11 11 11 0 0 11 11 22 0 0 0 0 9 0 0 2.043 93 1.00 288 288 0 0 0 0 0 0 0 0 0 22 22 0 0 0 11 22 0 11 11 0 9 0 0 1.735 79 1.00 ## INSERTION LIST AliNo IPOS JPOS Len Sequence 1 9 6 2 sVLv 1 115 112 1 pSp 1 158 155 7 nRIAAQEVp 1 176 173 1 mEp 1 192 188 1 eGd 2 9 8 2 mSNl 2 35 34 3 gSKGt 2 111 110 3 aVQRs 2 115 114 1 hDs 2 127 126 2 qGKq 2 130 129 25 dPHRYEEATSLFQKEVLDPQKLSRYAs 2 147 146 8 dAFQYGVMEy 2 158 157 8 aRHTDELDYf 2 176 175 1 sSl 2 192 191 1 eNd 2 268 266 1 fDt 3 54 51 1 tRh 3 115 112 1 gRg 3 158 155 1 eWr 3 176 170 2 gDRl 5 35 27 4 gFLQRt 5 115 107 1 qEg 5 158 150 1 vPr 6 9 9 2 aGLi 6 35 35 3 sYNAv 6 111 111 16 hHVCWGNGTENKKRDTFq 6 115 115 1 pDa 6 147 147 3 eVDEv 6 158 158 8 kEIPDAFERv 6 238 237 1 hEn 7 9 9 2 aGLi 7 35 35 3 sLPVv 7 115 115 1 aDs 7 147 147 3 nIPPa 7 158 158 8 kEIPPAFFRi 7 176 176 11 dDHTAGHGHPTDa 7 238 237 1 hTd 8 9 9 1 eIa 8 35 35 4 aHHGAa 8 115 115 1 kSs 8 147 147 8 eKGEVTPPPa 8 158 158 8 sKVYSDDQDl 8 176 176 1 dKk 8 238 237 1 hRs 9 9 7 1 eQg 9 35 33 4 nPNGSa 9 115 113 1 kSg 9 147 145 8 nDGGLVLKPa 9 158 156 8 nKAFVINNDm 9 176 174 1 dLk 9 192 190 1 tGd //