Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 E -1 1 -1 0 -4 1 3 -2 -1 -3 -3 5 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 33 0 0 0 0 67 0 0 0 0 0 0 0 0 0.61 0.12 2 G 1 -1 -1 -2 -3 -1 -1 5 -2 -3 -3 2 -2 -3 -2 0 -1 -3 -3 -3 15 0 0 0 0 0 0 59 0 0 0 26 0 0 0 0 0 0 0 0 0.63 0.12 3 G -1 -2 4 3 -3 -1 0 3 -1 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -4 0 0 39 28 0 0 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.12 4 S 3 -2 -1 -1 -1 -1 -1 2 -2 -2 -3 -1 -2 -3 -1 3 0 -3 -2 -1 39 0 0 0 0 0 0 13 0 0 0 0 0 0 0 48 0 0 0 0 0.43 0.12 5 L -2 -2 -3 -4 -2 -2 -3 -4 -3 1 4 -2 5 0 -3 -2 -1 -2 -1 0 0 0 0 0 0 0 0 0 0 0 61 0 39 0 0 0 0 0 0 0 0.53 0.12 6 A 4 -1 -1 -1 -1 0 2 -1 -1 -2 -2 -1 -2 -3 -1 2 0 -3 -2 -1 61 0 0 0 0 0 26 0 0 0 0 0 0 0 0 13 0 0 0 0 0.41 0.12 7 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.57 0.12 8 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.63 0.12 9 T 3 -2 -1 -2 -1 -1 -1 -1 -2 -1 -2 -1 -1 -3 -1 1 4 -3 -2 0 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61 0 0 0 0.45 0.12 10 A 4 -2 -1 -2 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 -1 1 3 -3 -2 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0.45 0.12 11 H -2 -1 0 -2 -3 0 0 -2 9 -4 -3 -1 -2 -2 -3 -1 -2 -3 1 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 1.17 0.12 12 Q -1 4 -1 -1 -4 5 1 -2 0 -3 -3 1 -1 -3 -2 -1 -1 -3 -2 -3 0 39 0 0 0 61 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.71 0.12 13 A 2 -3 -3 -3 -1 -2 -2 -2 -3 1 0 -2 0 -2 -2 -1 0 -3 -2 4 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0.35 0.12 14 C -1 -4 -3 -4 10 -3 -4 -3 -3 -2 -2 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.54 0.12 15 H 2 -2 -1 -2 -2 -1 -1 4 5 -3 -3 -1 -2 -3 -2 0 -1 -3 -1 -2 28 0 0 0 0 0 0 39 33 0 0 0 0 0 0 0 0 0 0 0 0.55 0.12 16 L -1 -3 -4 -4 -1 -3 -3 -4 -4 3 3 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 28 33 0 0 0 0 0 0 0 0 39 0.44 0.12 17 P -1 -3 -2 -2 -3 -2 -2 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.18 0.12 18 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.63 0.12 19 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 0 -2 -4 -2 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.91 0.12 20 T 1 -2 0 -1 -1 -1 -1 -1 -2 -1 -2 -1 -1 -3 -1 2 5 -3 -2 -1 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 72 0 0 0 0.50 0.12 21 F -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 1 4 -4 -3 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 67 0 0 33 0 0 0 0 0 0 0.54 0.12 22 T 4 -2 -1 -2 -1 -1 -1 -1 -2 -1 -2 -1 -1 -3 -1 1 3 -3 -2 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33 0 0 0 0.44 0.12 23 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.96 0.12 24 H 0 -1 0 -1 -2 0 0 -1 5 -3 -3 -1 -2 -2 -2 4 0 -3 0 -2 0 0 0 0 0 0 0 0 33 0 0 0 0 0 0 67 0 0 0 0 0.54 0.12 25 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.96 0.12 26 Q -1 1 0 -1 -3 5 1 -2 0 -3 -3 4 -1 -4 -2 0 -1 -3 -2 -3 0 0 0 0 0 61 0 0 0 0 0 39 0 0 0 0 0 0 0 0 0.66 0.12 27 P -1 -3 -2 -2 -3 -2 -2 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.18 0.12 28 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.96 0.12 29 G -1 -2 0 4 -3 -2 0 5 -2 -4 -4 -2 -3 -4 -2 -1 -2 -4 -4 -4 0 0 0 39 0 0 0 61 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.12 30 A 0 -3 -4 -4 -2 -2 -3 -3 -3 -1 2 -3 0 0 -3 -2 -2 9 1 -1 11 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0 0 50 0 0 1.10 0.12 31 E -1 -1 -1 0 -3 1 4 -2 -1 -3 -3 0 -2 -4 4 0 1 -3 -3 -2 0 0 0 0 0 0 61 0 0 0 0 0 0 0 26 0 13 0 0 0 0.74 0.12 32 Q -2 0 0 4 -4 4 3 -2 -1 -4 -3 0 -2 -4 -2 -1 -1 -3 -3 -3 0 0 0 39 0 33 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.12 33 L -2 -2 -1 4 -2 -2 -1 -3 -2 0 3 -2 1 -1 -3 -2 -2 -3 -2 -1 0 0 0 39 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0 0 0.40 0.12 34 E -1 -1 -1 -1 -2 0 3 -2 -2 -1 2 -1 0 -1 -2 2 0 -3 -2 -1 0 0 0 0 0 0 33 0 0 0 39 0 0 0 0 28 0 0 0 0 0.25 0.12 35 Q 0 0 0 -1 -2 5 1 -1 0 -3 -3 0 -1 -3 -1 3 0 -3 -2 -2 0 0 0 0 0 61 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0.56 0.12 36 C -1 -4 -3 -4 10 -3 -4 -3 -3 -2 -2 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.54 0.12 37 G 3 -2 -1 -2 -2 -2 -2 5 -2 -3 -3 -2 -2 -3 -2 0 -1 -3 -3 -2 39 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.12 38 Y -2 -2 -3 -4 -3 -2 -2 -4 1 -2 -1 -2 -1 3 -3 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.12 0.12 39 P -1 -1 2 -1 -3 3 0 -2 -1 -3 -3 0 -2 -4 6 -1 -1 -4 -3 -3 0 0 13 0 0 26 0 0 0 0 0 0 0 0 61 0 0 0 0 0 1.21 0.12 40 V 3 -2 -3 -3 -1 -2 -2 -2 -3 1 0 -2 0 -2 -2 -1 0 -3 -2 4 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61 0.34 0.12 41 Q -1 0 0 -1 -3 5 1 -2 5 -3 -3 1 -1 -3 -2 -1 -1 -2 -1 -3 0 0 0 0 0 72 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0.73 0.12 42 R -2 4 5 0 -3 2 0 -1 0 -4 -3 1 -2 -3 -2 0 -1 -4 -2 -3 0 33 54 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.61 0.12 43 L -2 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 1 0 -3 -3 -1 -2 -2 1 0 0 0 0 0 0 0 0 0 39 61 0 0 0 0 0 0 0 0 0 0.51 0.12 44 V -1 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 0 -1 -3 -2 0 -3 -2 5 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 85 0.51 0.12 45 A 3 -1 0 -1 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 -1 3 3 -3 -2 -1 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39 28 0 0 0 0.41 0.12 46 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.63 0.12 47 Y -2 -3 -3 -4 -3 -2 -3 -4 1 -1 -1 -3 -1 5 -4 -2 -2 1 6 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 0 61 0 0.92 0.12 48 L -1 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 1 0 -3 -3 -1 -2 -2 3 0 0 0 0 0 0 0 0 0 15 59 0 0 0 0 0 0 0 0 26 0.46 0.12 49 A 4 -2 -2 -3 -1 -2 -2 -1 -2 -1 2 -2 0 -2 -2 0 -1 -3 -2 0 72 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0.35 0.12 50 A 2 -2 -1 -2 -1 -1 -1 -1 -2 -1 -1 -1 2 -2 -2 1 4 -3 -2 0 33 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 52 0 0 0 0.36 0.12 51 R -2 5 0 -2 -4 1 0 -3 5 -4 -3 1 -2 -3 -3 -1 -2 -3 0 -3 0 69 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0 0 0 0.76 0.11 52 L -2 -3 -4 -4 -2 -3 -4 -4 -4 4 3 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0 0 0 0.50 0.11 53 S -1 -2 -2 -2 -2 -2 -2 -3 -3 0 3 -2 0 -1 4 2 -1 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 47 0 0 0 24 28 0 0 0 0 0.46 0.18 54 W -3 -3 -4 -5 -3 -3 -4 -3 -2 -2 -1 -4 -1 5 -4 -3 -3 10 2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0 53 0 0 1.61 0.18 55 N 0 -1 4 0 -2 -1 -1 -1 -1 -3 -3 -1 -2 -3 -2 4 2 -4 -2 -2 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 53 19 0 0 0 0.54 0.18 56 Q -2 0 0 -1 -4 5 1 -3 7 -4 -3 0 -1 -3 -2 -1 -2 -3 0 -3 0 0 0 0 0 53 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0.87 0.18 57 V -2 -3 -4 -4 -2 -3 -3 -4 -4 3 4 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 19 53 0 0 0 0 0 0 0 0 28 0.52 0.18 58 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.25 0.18 59 Q 0 -1 0 -1 -2 3 0 -1 -1 -3 -3 0 -2 -3 -2 4 2 -3 -2 -2 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 59 13 0 0 0 0.52 0.18 60 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 0 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 81 0.60 0.18 61 I -2 -4 -4 -4 -2 -4 -4 -4 -3 4 1 -4 0 5 -4 -3 -2 -1 1 1 0 0 0 0 0 0 0 0 0 53 0 0 0 47 0 0 0 0 0 0 0.64 0.18 62 R 1 3 -1 -1 -2 0 -1 -2 -1 -2 -2 0 -1 -2 -1 0 4 -2 -2 -1 13 29 1 1 0 1 1 1 0 1 2 1 0 1 1 1 42 0 1 1 0.34 0.15 63 N -1 -1 3 -1 -2 3 0 -2 -1 -1 2 -1 0 -2 -2 -1 -1 -2 -2 -1 1 1 29 1 0 25 1 1 0 1 30 1 0 1 1 1 1 0 1 1 0.26 0.15 64 A 3 -2 3 -1 -2 -1 -1 -1 -1 -2 -2 -1 -2 -3 -2 1 2 -3 -2 -1 53 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0.43 0.18 65 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.73 0.18 66 A 3 -1 3 -1 -2 3 0 -1 -1 -3 -3 0 -2 -3 -2 1 -1 -3 -2 -2 41 0 19 0 0 28 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0.41 0.18 67 S -1 -1 -1 -1 -2 0 3 -2 -2 -1 1 -1 -1 -2 -2 2 3 -3 -2 -1 0 0 0 0 0 0 28 0 0 0 19 0 0 0 0 28 24 0 0 0 0.31 0.18 68 P -2 -3 -2 2 -4 -2 -1 -3 -3 -3 -4 -2 -3 -4 7 -1 -2 -4 -4 -3 0 0 0 19 0 0 0 0 0 0 0 0 0 0 81 0 0 0 0 0 1.76 0.18 69 G -1 -2 -1 0 -4 0 4 4 -1 -4 -4 -1 -3 -4 -2 -1 -2 -3 -3 -3 0 0 0 0 0 0 53 47 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.18 70 S -1 -1 -1 2 -2 3 1 -2 -1 -1 -2 -1 -1 -3 -2 2 0 -3 -2 2 0 0 0 13 0 19 11 0 0 0 0 0 0 0 0 28 0 0 0 28 0.26 0.18 71 G 1 -2 -1 -1 -3 -1 2 5 -2 -3 -3 -1 -3 -3 -2 0 1 -3 -3 -2 15 0 0 0 0 0 19 53 0 0 0 0 0 0 0 0 14 0 0 0 0.58 0.18 72 G 0 -2 -1 -1 -3 -1 1 4 -2 -4 -4 -1 -3 -4 3 1 -1 -3 -3 -3 0 0 0 0 0 0 14 53 0 0 0 0 0 0 19 15 0 0 0 0 0.72 0.18 73 D -2 2 0 5 -4 3 3 -2 -1 -4 -3 0 -2 -4 -2 -1 -1 -4 -3 -3 0 14 0 43 0 24 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.18 74 L -2 -3 -4 -4 -2 -3 -3 -4 -4 1 4 -3 1 0 -3 -3 -2 -2 -2 2 0 0 0 0 0 0 0 0 0 0 81 0 0 0 0 0 0 0 0 19 0.61 0.18 75 G 3 2 -1 -2 -2 -1 -1 3 -2 -3 -3 -1 -2 -3 -2 1 -1 -3 -3 -2 44 15 0 0 0 0 0 28 0 0 0 0 0 0 0 14 0 0 0 0 0.44 0.18 76 E -1 2 -1 0 -3 4 4 -2 0 -3 -3 1 -2 -3 -1 -1 -1 -2 -2 -2 1 15 1 1 0 25 48 1 0 1 1 1 0 1 1 1 1 0 0 1 0.57 0.16 77 A 4 2 -2 -2 -1 -1 -1 -1 -2 1 -1 -1 -1 -3 -2 0 -1 -3 -2 0 66 19 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0.38 0.18 78 I -2 -3 1 -3 -2 -3 -3 -4 -3 4 3 -3 1 -1 -3 -2 -1 -3 -2 1 0 0 15 0 0 0 0 0 0 53 33 0 0 0 0 0 0 0 0 0 0.42 0.18 79 R -2 5 -1 3 -4 0 2 -3 -1 -4 -3 1 -2 -4 -2 -1 -2 -4 -3 -3 0 66 0 19 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.18 80 E -2 -1 2 3 -4 3 4 -2 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 15 19 0 14 53 0 0 0 0 0 0 0 0 0 0 0 0 0 0.70 0.18 81 Q -2 0 6 0 -3 3 0 -1 0 -4 -4 0 -2 -4 -2 0 -1 -4 -2 -3 0 0 72 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.18 82 P -1 -3 -3 -2 -3 -2 -2 -3 -3 -3 -4 -2 -3 -4 8 -1 -2 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.26 0.18 83 E 2 -2 -1 -1 -3 -1 3 4 -2 -3 -3 -1 -3 -4 -2 0 -1 -3 -3 -3 24 0 0 0 0 0 28 47 0 0 0 0 0 0 0 0 0 0 0 0 0.59 0.18 84 Q -1 1 -1 -2 -3 4 0 -3 -1 -1 0 0 6 -2 -2 -1 -1 -2 -2 -1 0 10 0 0 0 43 0 0 0 0 0 0 47 0 0 0 0 0 0 0 0.51 0.18 85 A 3 -2 -3 -3 -1 -2 -2 -2 -3 1 -1 -2 -1 -2 -2 0 -1 -3 -2 3 53 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0.41 0.18 86 R -2 5 -1 -2 -3 0 -1 -3 -2 1 -1 0 -1 -3 -2 -1 3 -3 -2 -1 0 53 0 0 0 0 0 0 0 19 0 0 0 0 0 0 28 0 0 0 0.47 0.18 87 L -2 -1 -2 -2 -3 5 0 -3 -1 0 3 -1 1 -1 -3 -2 -1 -2 -2 -1 0 0 0 0 0 47 0 0 0 0 53 0 0 0 0 0 0 0 0 0 0.46 0.18 88 A 3 -2 -3 -3 -1 -2 -2 -2 -3 1 -1 -2 -1 -2 -2 0 -1 -3 -2 3 53 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0.41 0.18 89 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.73 0.18 90 T 0 -2 0 -1 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -2 2 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 87 0 0 0 0.70 0.18 91 L -1 -3 -3 -4 -2 -2 -3 -4 -3 2 3 -3 4 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 0 28 0 24 0 0 0 0 0 0 47 0.48 0.18 92 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.67 0.18 93 A 3 4 -2 -2 -2 0 -1 -1 -1 -3 -2 0 -2 -3 -2 0 -1 -3 -2 -2 53 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.54 0.18 94 A 3 -1 -1 -2 -2 5 0 -1 -1 -3 -2 0 -1 -3 -2 0 -1 -3 -2 -2 53 0 0 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.54 0.18 95 E -2 -1 -2 -1 -3 3 3 -3 -2 4 0 -1 0 -2 -2 -2 -1 -3 -2 0 0 0 0 0 0 24 28 0 0 47 0 0 0 0 0 0 0 0 0 0 0.37 0.18 96 S 0 -2 -1 -2 -2 -1 -1 -2 0 -2 -2 -1 -2 1 -2 3 0 0 6 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53 0 0 47 0 0.60 0.18 97 E -2 -1 5 4 -4 0 3 -2 0 -4 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 47 24 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.18 98 R 2 3 0 5 -3 0 0 -2 -2 -3 -3 0 -3 -4 -2 0 -1 -4 -3 -3 24 28 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.56 0.18 99 F -3 -3 -3 -4 -3 -3 -3 -4 0 -1 -1 -3 -1 6 -4 -3 -2 1 6 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 53 0 0 0 0 47 0 1.01 0.18 100 V 0 -3 -2 -3 -1 -2 -2 -3 -3 2 0 -2 0 -2 -3 1 1 -3 -2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 11 0 0 76 0.43 0.18 101 R -1 4 -1 -2 -3 0 -1 -3 3 -2 -2 0 -2 -3 -2 0 4 -3 -1 -2 0 40 0 0 0 0 0 0 13 0 0 0 0 0 0 0 47 0 0 0 0.53 0.18 102 Q -2 0 0 -1 -4 5 1 -3 7 -4 -3 0 -1 -3 -2 -1 -2 -3 0 -3 0 0 0 0 0 53 0 0 47 0 0 0 0 0 0 0 0 0 0 0 0.87 0.18 103 G -1 -1 0 -2 -3 2 -1 3 7 -4 -4 -1 -2 -2 -3 -1 -2 -3 0 -4 0 0 0 0 0 13 0 28 59 0 0 0 0 0 0 0 0 0 0 0 0.82 0.18 104 T 2 -2 -2 -2 -2 -1 -1 -2 -2 -2 -2 -1 -2 -3 6 0 2 -4 -3 -1 29 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 26 0 0 0 0.88 0.16 105 G 0 -3 -1 2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 14 0 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 1.07 0.16 106 N -2 0 5 0 -3 4 0 -1 0 -4 -3 0 -2 -4 -2 0 -1 -3 -2 -3 0 0 54 0 0 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.16 107 D -1 -2 0 3 -2 -1 0 -2 -2 -2 -2 -1 -2 -3 -2 2 4 -3 -2 -1 0 0 0 26 0 0 0 0 0 0 0 0 0 0 0 15 59 0 0 0 0.53 0.16 108 E 0 0 0 0 -2 4 3 -2 -1 -3 -3 0 -2 -3 -2 3 0 -3 -2 -3 0 0 0 0 0 29 26 0 0 0 0 0 0 0 0 46 0 0 0 0 0.52 0.16 109 A 4 -1 -2 -1 -2 0 3 -1 -2 -2 -2 -1 -2 -3 -1 0 -1 -3 -2 -1 71 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0.49 0.16 110 G -1 -1 -1 -1 -3 3 -1 5 -2 -4 -4 -1 -2 -4 -2 -1 -2 -3 -3 -3 0 0 0 0 0 29 0 71 0 0 0 0 0 0 0 0 0 0 0 0 0.87 0.16 111 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.16 112 A 3 -1 -1 -2 -2 4 0 -1 -1 -2 -2 0 -1 -3 -2 0 -1 -3 -2 -1 54 0 0 0 0 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.50 0.16 113 N 3 -1 2 -1 -1 -1 -1 -1 -1 -2 -3 -1 -2 -3 -1 3 0 -3 -2 -1 46 0 13 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0.45 0.16 114 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.16 115 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.21 0.16 116 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 0 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 46 0 0 0 0 0 0 0 0 0 54 0.56 0.16 117 V -1 -3 -3 -4 -1 -2 -3 -4 -3 2 3 -3 3 -1 -3 -2 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 0 36 0 15 0 0 0 0 0 0 50 0.42 0.13 118 S 0 -1 4 0 -2 0 -1 -1 -1 -3 -3 -1 -2 -3 -2 4 1 -3 -2 -2 0 0 27 0 0 0 0 0 0 0 0 0 0 0 0 73 0 0 0 0 0.56 0.13 119 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.65 0.13 120 T -1 -2 -1 -2 -2 -2 -2 -3 -2 -1 -1 -2 -1 4 -2 0 4 -1 1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 64 0 0 0 0.48 0.13 121 C -1 -4 -3 -4 10 -3 -4 -3 -4 -2 -2 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.57 0.13 122 P -1 -3 -2 -2 -3 -2 -2 -3 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.20 0.13 123 V 2 -2 -1 4 -2 -1 0 -2 -2 0 -1 -2 -1 -2 -2 -1 -1 -4 -2 2 27 0 0 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37 0.30 0.13 124 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.59 0.13 125 A 1 -2 0 5 -3 -1 0 2 -2 -3 -3 -1 -3 -4 -2 0 -1 -4 -3 -3 23 0 0 63 0 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.13 126 G -1 0 -1 -2 -3 -1 -1 3 -2 -1 1 3 -1 -2 -2 -1 -2 -3 -2 -2 0 0 0 0 0 0 0 37 0 0 27 36 0 0 0 0 0 0 0 0 0.33 0.13 127 E -1 -1 3 1 -3 0 3 -2 -1 -3 -3 0 -2 -3 2 2 0 -4 -3 -3 0 0 27 0 0 0 37 0 0 0 0 0 0 0 13 23 0 0 0 0 0.51 0.13 128 C -1 -4 -3 -4 10 -3 -4 -3 -4 -2 -2 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.57 0.13 129 A 2 -2 -3 -3 -1 -2 -2 -2 -3 1 2 -2 0 -1 -2 -1 -1 -3 -2 3 37 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 36 0.28 0.13 130 G 2 -2 -1 -1 -2 -1 -2 5 -2 -3 -3 -1 -2 -3 -2 2 0 -3 -3 -2 21 0 0 0 0 0 0 56 0 0 0 0 0 0 0 23 0 0 0 0 0.59 0.06 131 P -1 -2 -2 -2 -3 -2 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.11 0.06 132 A 4 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.49 0.06 133 D -2 -2 1 6 -4 -1 1 -2 -1 -3 -4 -1 -3 -4 -2 0 -1 -5 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.06 134 S 1 -1 0 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.53 0.06 135 G 3 -2 -1 -2 -2 -2 -2 5 -2 -3 -3 -1 -2 -3 -2 0 -1 -3 -3 -2 44 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 0 0 0 0 0.62 0.06 136 D -2 -2 3 6 -4 0 1 -1 -1 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 23 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.85 0.06 137 A 4 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.49 0.06 138 L -2 -2 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06 139 L -1 -1 -2 -2 -2 4 0 -3 -1 0 3 0 1 -1 -2 -1 -1 -2 -1 0 0 0 0 0 0 44 0 0 0 0 56 0 0 0 0 0 0 0 0 0 0.31 0.06 140 E -1 0 0 1 -4 2 5 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.06 141 R -2 6 -1 -2 -4 1 0 -3 0 -3 -2 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.85 0.06 142 N -2 -1 5 4 -3 0 1 -1 0 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 56 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.06 143 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.99 0.06 K Lambda Standard Ungapped 0.1304 0.3150 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1491 0.3168 PSI Gapped 0.0456 0.2670