Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 G -3 -6 -4 -5 -6 -5 -5 8 -5 -7 -7 -5 -6 -7 -5 -3 -5 -6 -6 -7 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 2.40 1.63 2 S -2 -2 -2 -4 -2 -3 -4 -5 -2 -5 -4 -2 -4 -3 3 5 4 -2 -2 -4 2 2 1 0 1 0 0 0 1 0 2 2 0 1 16 46 23 1 1 1 1.02 1.90 3 H -5 -2 -2 -3 -7 -2 -4 -6 11 -7 -6 -4 -5 -3 -3 -4 -5 -6 1 -7 0 1 1 1 0 1 0 0 91 0 0 0 0 1 1 0 0 0 3 0 3.05 1.96 4 S -2 -4 -3 -4 -1 -3 -4 -4 -2 -4 -5 -4 -4 -2 -4 7 2 1 -3 -4 1 0 0 0 1 0 0 0 1 1 1 0 0 2 0 78 10 2 1 1 1.48 2.01 5 M -5 -4 -7 -7 -3 -4 -5 -7 -2 -2 6 -5 4 -1 -5 -6 -4 1 -1 -2 0 1 0 0 0 0 0 0 1 1 78 1 10 2 0 0 1 2 2 1 1.51 2.03 6 R -4 6 -1 -3 4 2 -3 -4 3 -3 -3 2 0 -3 -5 0 -1 1 -1 -4 1 36 2 1 7 9 1 1 7 1 3 12 2 1 0 6 3 2 2 1 0.78 2.06 7 Y -4 -4 -4 -5 -3 -5 -5 -5 0 -2 -2 -5 -3 3 -7 -4 -3 0 9 -2 1 1 1 1 1 0 0 1 2 2 3 0 1 7 0 1 2 0 75 2 2.10 2.04 8 F -5 -4 2 0 -2 -4 -3 -6 2 0 1 -4 -2 7 -7 -3 -2 -4 1 -2 1 1 9 5 1 1 1 0 5 6 11 1 0 48 0 2 2 0 4 2 1.10 2.10 9 H -4 -2 -2 -2 0 -2 -3 -5 3 0 1 -4 -2 4 -5 -1 -2 -3 7 0 1 2 2 3 2 2 2 1 6 5 11 1 1 14 0 6 3 0 32 7 0.77 2.10 10 T -3 -4 -3 -5 -2 -4 -5 -5 -3 0 -1 -3 2 -3 -3 -1 7 -3 -3 -2 2 1 1 0 1 0 0 0 1 5 5 1 5 1 1 2 70 0 1 2 1.38 2.11 11 S 4 -4 -5 -5 -2 -2 -3 3 -3 1 -2 -4 -1 -4 -4 0 0 -3 -3 2 35 1 0 0 1 2 1 18 1 8 4 1 1 1 1 6 5 0 1 13 0.55 2.12 12 V -1 -2 -2 -3 -3 -3 -4 -5 -3 2 1 -3 3 -1 -4 1 1 -2 -3 5 5 2 2 2 1 1 1 1 1 9 14 2 6 3 1 9 8 1 1 33 0.50 2.06 13 S -2 -3 -2 -4 -3 -3 -3 -4 -1 -3 -3 -3 -3 -2 0 6 2 -2 -1 -4 2 1 1 0 1 1 1 1 2 1 3 1 1 2 5 67 9 1 2 1 1.15 2.06 14 R -2 4 -1 1 -3 2 2 1 1 -4 -2 1 -3 -4 -1 -1 -2 1 -3 -4 3 24 2 8 1 8 12 11 3 1 5 7 1 1 3 5 2 2 1 1 0.40 2.04 15 P -2 -2 -3 0 -2 -2 -1 0 -1 -3 -2 -2 -3 -2 7 -2 -2 -2 -3 -1 4 3 1 4 1 2 4 7 2 1 4 2 1 2 50 3 2 1 1 6 1.02 2.04 16 G -1 1 -1 1 -2 -3 -1 5 -2 -1 -4 -2 -5 -4 -3 1 -1 0 -3 -1 5 8 2 7 1 1 4 35 1 4 2 2 0 1 2 11 3 1 1 5 0.44 2.00 17 R -2 2 -3 -1 -2 1 -1 -3 1 -2 1 -1 -1 -2 5 1 -1 2 -2 -3 3 11 1 3 1 6 4 2 3 2 12 3 2 2 26 9 5 2 1 1 0.40 2.02 18 G -2 0 0 0 -6 -1 0 6 -2 -4 -3 -3 -2 -3 -3 -2 -2 1 -5 -1 3 5 5 5 0 3 8 48 1 1 3 1 1 1 1 3 2 2 0 5 0.72 2.00 19 E -1 -1 -2 0 -2 3 2 -4 1 0 1 -1 -1 2 -2 -2 1 -5 -1 0 4 2 1 5 1 13 15 1 3 5 13 4 2 7 2 3 8 0 3 6 0.20 2.00 20 P -2 -2 -2 -2 -6 -1 -1 -2 1 -3 -2 -4 -1 -1 7 0 -1 0 -1 -5 3 2 2 2 0 3 3 3 3 2 5 0 2 3 53 9 4 2 2 0 1.15 1.95 21 R -1 4 0 -2 0 1 2 -3 2 -3 -2 0 1 -2 -1 -1 -2 6 -1 -3 6 19 4 2 2 7 11 3 5 2 5 5 4 2 4 3 2 10 2 2 0.38 1.98 22 F -4 -5 -1 -1 4 -5 -5 -2 1 -1 -1 -2 1 6 -1 -1 -4 -3 3 0 0 0 3 3 9 0 0 4 3 4 5 3 3 35 4 4 0 0 8 7 0.71 1.84 23 I -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 24 T -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 25 V -1 0 -1 -1 -5 0 -1 -2 1 0 0 -2 2 1 -1 -1 -1 2 0 4 5 4 3 4 0 5 4 3 3 5 8 3 5 5 3 5 4 3 3 26 0.21 1.90 26 G -1 0 1 0 3 1 0 -1 3 0 -1 -4 2 -4 0 0 0 -5 1 0 6 6 6 6 6 6 6 6 6 6 6 0 6 0 6 6 6 0 6 6 0.13 1.78 27 Y -4 -1 -2 -4 1 1 -1 -4 0 -2 0 -3 2 2 -5 -2 -3 3 7 -1 1 3 2 1 3 6 4 1 2 1 11 1 5 6 0 4 2 3 39 4 0.86 1.86 28 V -3 -5 -3 -6 -2 -5 -3 -4 -2 0 2 -5 1 -1 -5 -3 -2 -1 -2 6 1 0 1 0 1 0 2 2 1 3 16 0 4 2 0 2 1 1 1 60 1.05 1.84 29 D -5 -3 1 8 -6 -4 -1 -1 -1 -6 -6 -2 -6 -6 -2 -3 -4 -7 -6 -4 0 2 5 77 0 0 2 4 1 0 0 2 0 0 2 0 0 0 0 2 1.80 1.90 30 D -3 -1 0 6 -2 -1 1 3 -1 -6 -5 -1 -5 -6 -1 0 -2 -1 -2 -4 2 3 4 41 1 2 9 18 2 0 1 3 0 0 3 5 2 1 2 1 0.80 1.90 31 T -1 0 -1 -2 -1 4 1 -3 2 1 -2 1 -1 -2 -3 -2 2 -1 -2 2 4 5 3 2 1 16 8 2 5 6 4 7 1 2 1 2 13 1 1 16 0.29 2.11 32 L -2 -1 -2 -2 -5 6 1 -3 0 -2 0 -2 0 -2 3 -3 -2 0 -2 -2 3 4 2 3 0 36 8 2 3 3 10 2 2 2 12 2 2 1 1 3 0.65 2.05 33 F -3 -2 -2 -6 0 -2 -6 -3 -1 4 0 -3 3 6 -6 -3 -2 1 1 0 2 2 2 0 2 2 0 2 2 21 6 2 6 34 0 2 2 2 3 4 0.82 2.13 34 V -2 -2 -1 -1 1 -1 -1 1 -5 -1 1 -2 1 -1 -2 -1 1 2 0 3 4 3 3 4 3 3 4 10 0 4 11 3 4 3 3 4 7 2 4 18 0.09 2.19 35 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 36 F 0 1 -4 1 3 -4 -4 0 3 1 0 -4 -3 2 -4 0 -3 5 2 0 7 7 0 7 7 0 0 7 7 7 7 0 0 7 0 7 0 7 7 7 0.22 1.45 37 D -1 0 1 0 3 1 0 0 3 -4 -1 0 -4 -4 1 0 0 -5 1 0 6 6 6 6 6 6 6 6 6 0 6 6 0 0 6 6 6 0 6 6 0.08 1.78 38 S -1 0 0 0 3 0 0 -1 2 0 -4 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 0 5 5 5 5 5 5 5 5 5 0.09 2.12 39 D -1 0 1 0 3 1 0 -1 2 0 -1 0 -4 -4 0 0 0 -5 1 0 6 6 5 6 5 5 6 6 5 6 6 6 0 0 6 6 6 0 5 6 0.05 1.89 40 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 41 A 1 2 -1 -1 0 1 1 -1 0 -2 -2 1 0 -2 1 -1 -1 1 -1 -1 10 12 3 3 2 6 10 6 2 3 3 7 2 2 8 4 4 2 2 4 0.09 2.14 42 S -2 1 1 -1 1 0 -1 -2 1 -1 -2 1 0 -1 -1 2 2 2 -1 -1 3 8 7 3 2 4 5 3 3 3 3 7 3 3 3 14 14 2 2 4 0.12 2.22 43 P -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 44 R -2 4 -1 -1 1 0 0 -2 1 0 -1 2 1 -1 -2 -1 0 2 -5 -1 3 21 3 3 3 5 6 3 3 6 5 11 3 3 3 4 5 3 0 5 0.22 2.19 45 E 1 -2 -1 -2 0 0 0 -3 0 0 -1 0 4 0 0 -1 0 -5 1 0 14 2 3 3 2 5 7 2 2 5 6 6 9 4 6 5 5 0 5 6 0.09 2.06 46 E -2 0 -1 -1 1 2 3 -2 1 0 -1 2 1 0 -1 -2 -1 -5 -4 0 3 5 3 4 3 8 16 4 3 4 6 12 3 4 3 3 3 0 0 8 0.15 2.01 47 P -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 48 R -2 4 -2 -1 1 0 -2 -3 0 -1 0 1 0 -1 0 -2 -1 4 -1 -1 3 21 2 4 3 5 2 2 2 3 8 10 2 3 6 4 3 5 2 6 0.21 2.22 49 A 1 -1 -1 -2 1 2 -1 0 0 -1 -2 -2 1 -1 -1 -1 0 5 -1 0 13 3 2 3 3 10 3 8 2 3 4 3 4 3 3 4 7 7 2 8 0.13 2.18 50 P -1 0 -1 2 1 1 1 -2 2 -2 -2 -1 2 -5 3 -1 -1 2 -1 -2 6 4 3 11 2 5 8 4 4 3 4 4 5 0 15 5 3 3 3 3 0.17 2.17 51 W -2 0 -1 -2 0 1 0 -2 0 -2 -1 -1 0 0 -2 -1 -2 9 0 -2 4 5 3 3 2 6 6 3 3 3 5 3 3 3 3 4 3 28 3 3 0.75 2.22 52 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 53 E -1 1 -1 -1 -1 2 3 -2 0 -3 -2 3 -1 -1 -2 0 -1 0 -1 -2 6 6 3 3 1 7 18 4 2 2 5 15 2 3 2 6 4 1 2 3 0.17 2.22 54 Q 0 1 1 0 1 2 1 -1 1 -2 -2 1 0 0 -1 -1 0 2 -1 -2 7 7 6 5 2 10 9 5 3 3 3 9 3 4 3 4 5 3 3 3 0.07 2.18 55 E -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 56 G -1 -2 -1 2 -5 -1 0 2 1 -1 -1 -1 1 -1 -1 -1 0 2 -1 0 5 2 3 13 0 3 6 16 3 3 7 3 4 3 3 3 6 3 2 7 0.12 2.12 57 P -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 58 E 0 0 0 1 -5 1 2 -2 2 -1 -2 0 0 -5 0 0 0 3 0 -1 9 5 5 7 0 7 12 4 5 3 4 4 3 0 6 6 6 3 3 5 0.09 2.12 59 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 60 W -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 61 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 62 R -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 63 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 64 T -1 -1 0 -1 1 0 0 -2 1 -1 -2 -1 0 -1 -2 -1 4 2 0 -2 4 4 4 3 2 5 7 3 3 3 3 4 3 3 3 5 27 3 4 3 0.25 2.24 65 Q -2 2 -1 -1 0 4 0 -1 1 -2 -2 -1 0 -1 -1 -1 1 2 0 -2 4 12 3 3 2 15 7 5 3 3 4 4 3 3 3 4 8 3 3 3 0.15 2.23 66 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 67 C 1 0 0 -1 3 0 0 -2 0 1 0 -1 1 1 -1 0 -1 2 0 -1 10 5 4 4 6 4 5 4 3 7 8 3 4 5 3 7 4 3 3 5 0.02 2.24 68 K -1 1 -1 -2 1 1 -1 -2 0 0 0 3 2 0 -2 -2 -1 2 0 -1 5 8 3 3 3 5 5 3 3 5 7 18 4 4 3 4 4 3 3 5 0.10 2.23 69 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 70 K -1 1 2 0 1 0 0 0 2 -1 -2 0 0 -1 -2 0 0 3 0 -1 6 7 10 4 3 4 5 8 4 3 4 6 3 3 3 6 6 4 4 4 0.04 2.23 71 A 0 -1 -1 1 1 2 2 -1 2 -1 -1 -1 1 -1 -1 -1 -1 3 0 -1 7 4 3 8 3 8 15 4 4 4 5 4 4 3 3 4 4 3 3 4 0.09 2.17 72 Q -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 73 T -1 0 0 -1 1 1 -1 -1 1 1 -1 -1 2 0 -2 -1 0 3 1 1 4 5 4 4 3 5 4 6 3 7 6 4 4 4 3 5 7 4 4 9 0.01 2.17 74 D -2 -1 0 1 0 0 -1 -2 1 -1 -1 -2 1 6 -2 -2 -2 1 2 -2 3 3 4 7 2 5 4 3 3 3 5 3 4 27 2 4 3 2 7 3 0.35 2.18 75 R -2 3 -1 -1 0 0 -1 -2 1 -1 -1 2 2 1 -1 -2 -2 3 0 -2 3 18 3 4 2 5 3 4 3 4 5 12 4 6 3 3 3 4 3 3 0.17 2.23 76 E -1 1 -1 -1 1 0 0 -1 1 -1 -1 1 1 0 -1 -2 -2 3 0 2 5 7 3 3 2 3 6 6 3 4 7 8 3 3 3 3 3 4 3 14 0.04 2.23 77 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 78 L -2 -1 0 0 -5 -1 -1 -2 1 1 3 -2 2 0 -1 -2 -1 2 0 0 3 3 4 5 0 3 4 3 3 8 24 3 5 4 3 3 4 3 3 6 0.13 2.13 79 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 80 T 0 -1 1 0 -1 -1 -1 -3 0 2 0 -1 0 0 -3 -1 3 2 -2 -1 7 3 8 5 1 3 4 2 2 10 8 4 2 4 2 3 17 3 2 4 0.12 2.24 81 L 0 -2 -1 -2 0 -2 -2 -3 0 0 3 -2 2 -1 1 -2 0 2 -1 0 9 3 3 2 2 2 3 2 2 6 26 2 4 2 6 4 6 2 2 6 0.15 2.25 82 L -2 1 -2 0 -1 0 -2 -2 0 1 2 1 4 0 -1 -2 -1 2 -1 -1 4 8 2 5 2 5 3 3 3 7 16 8 9 3 3 3 3 3 2 5 0.12 2.24 83 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 84 Y -1 2 0 -1 1 2 0 -1 2 -1 -2 0 1 0 -1 -2 0 2 2 -2 4 11 5 4 3 8 7 4 5 3 4 7 3 3 3 3 5 3 6 3 0.08 2.24 85 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 86 N -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 87 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 88 S -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 89 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 90 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 91 G -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 92 S -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 93 H -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 94 T -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 95 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 96 Q -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 97 N -2 1 -1 -1 2 2 -1 -1 1 0 -1 -1 4 0 -2 -1 -1 5 0 0 4 6 3 3 5 11 4 5 3 4 5 4 9 4 3 4 5 8 4 7 0.23 2.12 98 M -1 0 0 -5 3 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.07 2.12 99 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 100 G -1 0 0 0 3 1 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.07 2.01 101 C -1 0 0 0 3 0 0 -1 -4 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 102 D -2 0 -1 2 6 0 2 -1 1 -1 -2 -2 0 -1 -2 -1 -1 2 0 -2 3 5 3 11 14 5 13 4 3 4 4 3 3 3 3 4 3 3 3 4 0.29 2.24 103 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 104 G -2 0 -1 2 3 0 1 2 1 -2 0 -1 0 -2 -1 -2 -2 1 -1 -2 3 6 3 13 5 4 10 15 3 3 12 3 3 2 3 3 2 2 2 3 0.17 2.08 105 P -1 0 0 0 -5 1 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.01 106 D -1 0 1 0 -5 1 0 0 3 -4 -1 0 -4 1 1 0 0 -5 2 0 6 6 6 6 0 6 6 6 6 0 6 6 0 6 6 6 6 0 6 6 0.05 1.78 107 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 108 R -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 109 L -1 -1 -1 -1 1 -1 1 -2 1 -1 1 -1 -4 3 0 1 1 -5 2 -1 4 4 3 3 3 3 8 3 3 3 13 5 0 10 4 9 10 0 6 4 0.10 2.07 110 L -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 111 R -1 0 0 0 3 0 0 -1 2 0 -1 0 -4 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 5 5 5 5 5 0.05 2.12 112 G -1 -1 -1 0 2 0 -1 4 2 -2 -3 -2 0 2 0 -1 -2 4 1 -2 5 4 3 5 4 4 3 27 4 3 3 3 3 8 5 4 3 5 4 3 0.30 2.21 113 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 114 H -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 115 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 116 H -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 117 A -1 0 0 0 3 1 0 -1 2 0 -1 -4 -4 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 0 0 5 5 5 5 5 5 5 0.08 2.01 118 Y -2 -1 -1 -1 1 -4 -4 -2 1 0 -2 -1 0 3 0 -1 -1 2 6 -2 3 4 3 4 3 0 0 3 3 4 4 4 3 11 6 4 3 3 27 3 0.46 1.84 119 D 0 1 1 0 -5 1 0 0 3 0 -1 0 -4 -4 1 0 -4 -5 2 0 6 6 6 6 0 6 6 6 6 6 6 6 0 0 6 6 0 0 6 6 0.07 1.67 120 G -2 -1 -2 -1 -1 -1 -1 6 -5 -3 -3 -2 -1 -6 -2 -2 -1 1 -5 -4 2 3 2 3 1 3 4 63 0 1 2 2 1 0 2 3 3 2 0 1 1.09 1.91 121 K -1 2 0 -2 0 4 3 -2 2 -1 -3 1 -1 -5 -1 -2 -2 1 0 -2 5 11 3 2 2 19 17 3 5 3 3 6 2 0 3 3 3 2 4 3 0.35 1.99 122 D -2 -1 1 5 -5 0 0 -1 2 0 -2 -1 3 -5 0 -1 0 -5 0 -2 3 3 6 26 0 4 7 4 4 6 4 3 7 0 4 3 5 0 3 3 0.34 1.96 123 Y -1 0 0 0 3 -4 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.12 2.01 124 I -2 -2 -1 -2 1 -1 -2 -2 -5 3 2 -2 4 0 -1 -2 0 2 -4 0 3 3 3 3 3 3 3 3 0 18 21 3 8 3 4 4 5 3 0 4 0.29 2.07 125 A 2 0 -1 -1 2 0 0 0 0 -2 -2 -1 0 -1 -2 1 1 3 0 -1 16 6 3 3 4 5 6 6 3 3 4 3 3 3 3 11 8 4 3 4 0.13 2.07 126 L -1 0 -4 0 3 1 -4 -1 2 0 -1 -4 2 1 0 0 -4 4 2 0 6 6 0 6 6 6 0 6 6 6 6 0 6 6 6 6 0 6 6 6 0.17 1.78 127 N -2 -1 4 4 1 0 -1 -1 2 -2 -2 -1 -4 -5 -1 -1 -1 -5 0 -1 4 3 19 23 3 4 4 4 5 3 4 3 0 0 3 5 4 0 4 4 0.42 1.79 128 E -1 -1 -1 0 -5 -1 1 -2 0 -1 1 1 2 -1 2 -1 1 2 0 -1 6 3 3 4 0 3 8 4 3 3 15 10 4 3 9 4 9 3 4 3 0.12 2.06 129 D -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 130 L -2 0 1 -2 0 -1 -1 -2 1 -1 -1 0 1 -1 -2 0 4 2 -1 -2 3 4 6 3 2 3 4 3 4 4 8 6 4 3 3 8 22 2 3 3 0.17 2.17 131 S -3 3 -2 -3 -1 1 0 2 2 -2 1 0 2 -3 -1 -1 -2 2 -2 -2 1 13 2 1 2 6 6 14 5 2 16 7 5 1 3 4 3 3 1 3 0.20 2.09 132 S -1 2 0 -1 0 0 0 -3 0 -1 -3 -1 -1 -1 -3 2 4 0 -2 -1 4 10 4 3 2 4 5 2 2 4 2 4 1 3 2 14 24 1 2 4 0.28 2.08 133 W -4 -1 -1 -5 3 0 -5 -2 1 -1 -2 -4 2 2 -1 -2 -1 10 1 -2 0 4 3 0 6 4 0 4 3 4 4 0 4 7 3 4 5 33 5 3 1.06 1.84 134 T -1 0 1 0 -5 1 0 -1 -4 0 -1 0 2 1 0 0 0 4 -4 0 6 6 5 6 0 5 6 6 0 6 6 6 5 5 6 6 6 5 0 6 0.05 1.89 135 A 3 -2 -1 -1 -5 -1 -2 0 0 -1 -2 -2 1 -1 0 -1 1 2 0 0 28 3 3 3 0 3 3 8 2 3 3 3 3 3 5 5 7 3 3 7 0.21 2.01 136 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 137 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 138 T -1 -1 1 -1 -5 1 -1 -2 2 -2 -2 -1 1 -1 4 0 2 2 -1 -2 4 4 7 4 0 6 3 3 4 3 3 4 4 3 18 7 11 2 3 3 0.21 2.18 139 A 2 -1 -4 -2 0 3 2 0 0 -1 -3 -1 1 -2 -1 -1 -2 1 -1 0 18 3 0 2 2 15 14 6 2 3 3 3 3 2 3 4 3 2 2 7 0.24 2.17 140 A 6 -2 -5 -2 0 -2 -2 -1 -1 -3 -3 -4 -1 -2 -1 0 -1 -6 -5 -2 59 2 0 2 2 2 2 5 2 2 2 0 1 2 3 5 4 0 0 3 0.83 2.08 141 Q -1 2 -1 -1 1 3 0 -1 1 -1 -1 -1 1 0 -2 -1 -1 3 0 0 4 9 3 3 2 15 7 4 3 3 6 4 3 4 3 4 3 3 3 8 0.10 2.23 142 I -1 0 0 -1 1 0 -1 -2 1 4 -2 -1 1 0 0 -1 0 3 0 -1 5 5 4 3 2 4 4 4 3 19 4 3 3 4 5 4 6 4 3 4 0.11 2.24 143 T -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 144 Q -1 2 -1 -2 0 2 -1 -2 0 -2 -2 5 0 -2 -2 0 -1 1 -5 -2 4 10 3 2 2 9 3 3 2 2 4 33 2 2 2 6 3 2 0 2 0.44 2.22 145 R -2 4 0 -1 0 3 -1 -2 2 -2 -1 0 1 -1 -1 -1 -1 2 0 -2 3 20 4 4 2 13 4 3 5 3 5 5 3 3 3 4 5 3 3 4 0.23 2.24 146 K -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 147 W -2 -2 -1 -2 2 -2 -1 -3 -5 -2 -1 -3 0 0 -2 -2 -2 11 0 -2 3 3 3 3 4 2 5 2 0 2 7 2 3 3 2 3 2 42 2 3 1.31 2.07 148 E -2 -1 2 1 -6 0 5 -2 0 -1 -2 0 0 -2 -2 -2 -1 -6 -5 -1 3 3 8 8 0 3 35 3 2 4 4 5 3 2 2 2 4 0 0 5 0.42 2.11 149 A -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 150 A 1 -1 2 3 1 0 1 -2 1 -1 -2 -1 1 -1 -1 -1 -1 2 0 -1 11 4 10 14 3 4 8 3 3 4 4 3 3 2 3 5 4 2 3 5 0.11 2.18 151 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 152 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 153 A 4 0 -1 -1 1 -1 -1 -1 0 -1 -2 -1 1 -1 -1 -1 0 2 0 -1 28 5 3 4 2 3 4 5 2 4 4 4 3 3 3 4 5 3 3 4 0.18 2.26 154 E -1 -1 1 0 -1 1 5 -3 0 -2 -1 0 0 -2 -2 -2 0 1 -2 -2 5 3 8 4 2 5 31 2 2 3 7 6 2 2 2 2 5 2 2 2 0.34 2.26 155 Q -2 3 -1 -1 -1 4 -1 -2 4 -2 -3 0 0 1 -3 -1 -2 0 2 -3 3 14 3 4 1 20 4 4 8 2 3 5 2 6 2 5 2 1 8 2 0.36 2.28 156 L -3 1 1 0 -1 1 -1 -4 1 -1 -1 -2 1 1 -3 -2 -1 7 4 0 2 8 6 5 1 6 5 1 3 3 7 2 3 5 1 3 5 12 11 6 0.35 2.27 157 R -3 5 -2 -2 -6 0 -1 -3 -1 -4 -4 6 -1 -2 -3 -2 -1 -1 -3 -4 2 25 2 2 0 3 3 2 1 1 1 43 1 2 1 2 5 1 1 1 0.94 2.22 158 A 2 -2 5 -1 -2 -1 -2 -2 3 -1 -4 0 -1 -2 -3 0 0 0 -1 -2 17 2 28 4 1 3 2 3 7 3 1 6 1 2 1 6 5 1 2 3 0.46 2.24 159 Y -3 -4 -3 -4 -2 -3 -4 -5 1 -2 -3 -3 -2 3 -6 -4 -3 1 9 -2 2 1 1 1 1 1 1 1 2 2 2 2 1 11 0 1 2 2 61 3 1.67 2.24 160 L -4 -3 -5 -7 -2 -4 -4 -6 -2 -1 6 -4 1 0 -5 -2 -4 -1 1 1 1 1 1 0 1 1 1 1 1 3 63 1 3 3 1 4 1 1 4 7 1.00 2.27 161 E -3 -2 -1 -2 -3 2 5 -2 -1 -3 -2 1 1 -4 -4 -1 3 -6 -3 -3 1 2 2 2 1 8 40 3 1 2 4 8 4 1 1 3 15 0 1 2 0.68 2.25 162 G -2 -2 2 -1 -1 3 1 4 3 -4 -5 0 -4 -4 -3 -1 -1 -2 -2 -3 3 2 10 4 1 13 10 26 8 1 1 6 0 1 1 3 4 1 2 2 0.46 2.27 163 E -3 0 -2 2 -2 -2 4 -3 -3 2 -2 -1 -1 -4 -3 -1 3 -2 -3 -1 1 5 2 12 1 1 25 2 1 11 4 3 1 1 1 4 17 1 1 5 0.42 2.27 164 C -4 -5 -5 -7 12 -7 -7 -5 -7 -3 -3 -7 -3 -1 -7 -4 -4 -2 -3 -4 0 1 1 0 88 0 0 1 0 1 2 0 1 2 0 1 1 1 1 1 3.24 2.21 165 V -3 -2 -3 -6 1 -3 -6 -5 -2 4 0 -3 1 -3 5 -3 -2 -3 -4 4 2 3 1 0 3 1 0 1 1 19 7 1 3 1 24 2 2 0 1 28 0.80 2.18 166 E -1 -1 -1 2 -4 2 5 -1 1 -4 -3 0 -3 -6 -2 -2 -3 -2 -2 -4 6 3 2 9 0 8 41 5 3 1 4 6 1 0 2 2 1 1 2 1 0.66 2.18 167 W -4 1 -3 -5 -2 -1 -4 -2 -1 -4 -2 -1 -1 -1 -5 -1 -2 12 -1 -4 1 7 1 1 1 3 1 3 1 1 5 4 2 2 1 5 3 57 1 1 2.09 2.18 168 L -5 -6 -7 -7 -5 -4 -7 -6 -4 0 6 -6 1 -1 -4 -5 -5 -5 -2 -1 0 0 0 0 0 1 0 1 1 3 86 0 2 2 1 1 0 0 1 3 1.64 2.14 169 R -4 5 -2 -3 -4 4 -1 -3 2 -5 -1 5 -3 -3 -4 -2 -3 0 -4 -5 1 26 2 1 0 16 2 2 5 1 7 29 0 1 1 3 1 1 0 0 0.85 2.15 170 R -3 5 -2 -1 -6 -1 -1 -2 -3 -2 -3 5 1 -6 -4 -2 -1 -2 -4 -3 2 30 1 4 0 2 4 3 0 2 3 36 4 0 1 3 3 1 0 2 0.90 2.14 171 Y -5 -5 -5 -6 -2 -2 -5 -6 4 -4 -2 -5 -2 4 -6 -4 -4 -2 9 -4 0 0 0 0 1 2 1 1 10 1 4 0 1 17 0 1 1 0 59 1 1.86 2.15 172 L -5 -4 -5 -6 -5 -4 -6 -6 -6 0 6 -5 2 -3 -5 -5 -4 -2 -3 3 0 1 0 0 0 1 0 0 0 4 67 0 5 0 1 0 0 1 0 17 1.28 2.14 173 E -2 0 1 2 -4 1 5 -1 -1 -4 -4 0 -2 -5 -2 0 -2 -7 -4 -2 4 4 7 10 0 7 38 4 2 1 2 6 1 0 2 5 2 0 0 4 0.59 2.14 174 N -4 -1 2 -4 -1 -3 -4 -5 4 -3 -1 0 2 0 -4 0 -2 -2 7 -4 1 4 11 1 1 1 1 1 9 1 6 6 5 2 1 6 2 0 40 1 0.99 2.13 175 G -2 -1 -4 -4 -4 -3 -2 7 -6 -3 -5 -4 -3 -6 -6 -2 -4 6 -5 -5 2 4 0 0 0 1 2 72 0 2 1 1 1 0 0 2 1 9 0 0 1.63 2.11 176 K -4 4 0 -2 -7 1 1 -4 -3 -5 -5 6 -1 -7 -4 -1 -3 -3 -6 -5 0 17 4 2 0 6 8 1 0 1 1 51 1 0 1 5 1 0 0 0 1.12 2.10 177 E -1 -1 -1 1 -6 -1 5 0 -2 -5 -5 2 -4 -5 -4 3 -1 -4 -4 -5 5 3 2 8 0 2 34 6 1 0 1 12 0 0 1 19 3 0 0 1 0.69 2.10 178 T -1 -2 -1 -1 -3 -1 -1 -5 -2 0 -3 -3 3 2 -4 2 5 -6 -1 0 5 2 3 3 0 2 5 0 1 5 2 1 7 8 0 16 31 0 2 6 0.52 2.10 179 L -5 -5 -7 -7 -5 -4 -6 -7 -4 -1 7 -6 0 -1 -5 -5 -4 -3 -5 -2 0 0 0 0 0 1 0 0 0 1 91 0 1 1 1 1 1 0 0 2 1.74 2.06 180 Q -4 -2 -2 -1 -6 6 4 -4 -1 -4 2 -1 3 -4 -5 -4 -2 -6 -4 -4 1 2 1 3 0 31 25 1 1 0 19 3 7 1 0 0 2 0 0 1 0.86 2.03 181 R -5 8 -4 -5 -7 -2 -3 -6 -4 -7 -6 3 -5 -7 -6 -4 -5 -6 -5 -6 0 88 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 2.30 1.89 K Lambda Standard Ungapped 0.1332 0.3170 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1090 0.3181 PSI Gapped 0.0334 0.2670