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>lupas_21
>lupas_14
>lupas_28
>jnet
>conf
>sol25
>sol5
>sol0
>jhmm
>jpssm
 * iteration 1
 S                         T                                           T                                             S          T                          T                                                                                                         S           TT      T    T      TTTT      SSS      N       TTT            T     T                 T      S S  TTS                       T                                             N T        S        N           STT     SS                                                T                                           N                                                                                                                                                                                                                          TTT                        T                  9     
 SRR      RR        RR     G            RRR          RR                G          R  RRR                             G     RRRRRS         RRRRRR  RRRR     G  RRRRR                 RRRR          RRRR     RR    RR     S   RR                       RRRRG      RR G SR        R SGRR    G   RGRRRRRRDDDG  RR  GGG      T   R   SSSRRR         N     GS R              G      TST  SFF      E               NG  R        YY   S                F G         S G  F     F        E         YFTGG     RR                                                Q             R              G F           GR                      R  R            F                                                                                                                                                                                   FFF                        F                  9     
 PAAAAA   AA        AA   AAC            AAAAAAAA     AA                S          A  AAA                             C     AAAAACAA       AAAAAA  AAAA     A  AAAAA     AA          AAAA          AAAA     AA    AA     S   AA                       AAAAA  AA  AAAA CA      AAA CGAAPP  C   ASAAAAAAEEESAAAA  DDD      P   A   CCCAASAA   A   C     VP A A            I     ACPC  PPP    PPP     AAA   A   CS  A PP  SPPAAPP P     PP      PPAP C         PAV  P     P A      P       A PPCCC     VV                         P                      T       PP    A              V A  PP PP    SA                      A  P            P                                                                                                                                                     PPPPP                         PPP                     P  I       P          7B    
 IVVVVV   VV        VV   VVV            VVVVVVVV     VV                I          V  VVV                             L     VVVVVIVV       VVVVVV  VVVV     V  VVVVV     VV          VVVV          VVVV     VV    VV     I   VV                       VVVVI  VV  VVII IV      VVV IVVVII  I   VIIIIIIIIIIIVVVV  VVV      V   V   IIIVVIII   V   I     IIVV I            I     VIII  III    FFV     VVI   V   II  V II  IFFVVFF I     FF      FFVI I         III  I     I V      I   I   I VIIVV     II                     I   II I        I         II       FF    I              I T  FF FF    IV      I               V  F            I                                                                                                              II     III                             VVVVV               V         VVV                     AVVII   I  V I       E4BB EE
 ATTTTT   TT        TT   TTA       GGKKKTTTSSSTTGG   TT                AKKK       T  TTT        GG  KKK              A     TTTTTATT       TTTTTT  TTTT     G  TTTTTKKK  TT  KKKKK   TTTT        KKTTTT     TT    TT     A   TTGG                GG   TTTTA  TT  TTTA AT      TTT ASTTEEKKA   TAVVVVVVKKKATTTT  KKK      A   T   AAATTATT   T   A     AAKT T            S     TAAA  AAA    SSGGG   TTA   T   AA  T EE  ASSAASS A     RRGG   ASSTA A         AAA  S GGGGAGTGGG   S   A   S ASAAA     HH GGG           G   SSD   CAGA        AGG  GG   AG GG  GGQQ    T         GG SSAGG  RR QQ    AV      Q     KAA    K  T AR            C                                                                             GG                               RR     KKK                             TTTTT               K         AAA    G              A SSKTL   L  L T       E8B  EE
 AGGGGG   GG        GG   GGG       GGGGGGGGGGGGGGG   GG    GGG         GGGG       G  GGG        GG  GGG              G     GGGGGGGG       GGGGGG  GGGG     G  GGGGGGGG  GG  GGGGG   GGGG        GGGGGG     GG    GG     G   GGGG            G   GG   GGGGG  GG  GGGG GG      GGG GGGGGGGGG   GGGGGGGGSSSGGGGG  GGG      A   G   GGGGGGGG   G   G    GGAGG G       GGGG G     GGAG  GGG GGGDDAGG   GGG   GGGGGG  G GGGGGDDGGDD G G   AAGGGGGGDDGG GGGGGGGGG GGGGGG GGGGGGGGGG   G   GGG G GGGGG     GG GGG GGG    GG GGGGGGG G GGGGGGGGGGGGGGG  GG GGGG GG  GGAA    G  GGGGG  GG GGGGGGGGG GG  GGGGGGGG  G   GGGGG    G  G GGG           G                                                                             AA   GGGGG                       GG     GGG        GGG                  GGGGG               C         GGG    G              Q GGGGA GGS GC G       E9BBBEE
 IYYYYY   YY        YY   YYVII     LLFFFYYYYYYYYLL   YY  IIFFF         VFFF       Y  YYY        LLFFFFF              V   IIYYYYYVYY       YYYYYY  YYYY     V  YYYYYFFF  YY  FFFFF   YYYY        FFYYYY     YY    YY     L   YYII            Y   LL   YYYY  IYY  YYFV IY    IIYYY VVYYLLFFI   YVYYYYYYFFFVYYYYIIFFF  FF  I   Y   VVVYYLYY   Y FFVIIIIFVIYYIFIIIIIF YYYYIM II IYIIII IVV LLLIIVIIY  YYLYY YFFFIVIIYILLIILIIIIIIIYIL   LLIIFFFFIIYVVVIIFFFFLL YLIVVV IIIIIVYIIIFFVI  VVYY Y VIVLLIIYY VVLIILLIIIYYYYIIILLLLIIILLLVTRILLLLLLVVTIILLII IIVV II  LLII    Y  VLLVV  II FFVLFGGVVVVV  GGVYGGVV LI FLLLFMM    V  Y VFV           VVVVVVVVVVVVV II     IIIIIIIIIIIII  VVV                 LLLLL VVVVV     VVV   II   IIIII     FFFFF     VVVVV   IIVVVVYIII  IIIIIIIII                  LLLLL VFFF    VVVV  IIIII     LLLVVV V       I  IIIII VFIVVFIVV FT I       E9BB EE
 FKKKKK   TT        RR   RRLVV     VVFFFTTTLLLRRVV   TT  VVSSS         FFFF       R  TTT        VVLLFFF              Y   VVTTTTTLKK       KKTTRR  TTRR     L  PPPRRFFF  KK  FFFFF   TTTT        FFKKPP     RR    PP     L   TTII            T   VV   TTKKA VTT  TTD  YN    VVKKN FYKKAAFFM  VKYTTTTTTYYYQTTKKVVTTT  FF  L   K   LLYKKYVV   R IILVVVVKAFAKVKVVLLLI KKKKLK LL LKYFYL IFY LLLKKFIII  KKYLL KKKKLAIIRLAAIIYKKLLKKVWLM   KKVVLLLSKKKYVTVVILLLLL WYSLLL LLFFYITVVVFFLI  VIRR I LFYLLVLLL IIIVVVIKKKVVVVIILILLLIITIIIFVIIILLLLLIIIVVVIVV VVTY PP  LLKK    R  VLLII  TT FFIKRLLQQSQQ  LLTRLLII IL FYIIFLL    L  R VPL           YIIIIIIIIVFFF TT     WWWWWWWWWWWWW  ILL             IIIILLLLL IIIII     KKKLLLEE   VVVVV     LLLLL     LLLLL   RRKKKKVKKK  LLLLLLKKK                  IIIII IIII    KKKK  VVVVV     IIIKKK L       V  LLLLT YYKMIVVLL LE VI      E8B  EE
 DDDDDD   DD        DD   DDLDD     DDDDDDDDDDDDDDD   DD  DDDDD         IDDD       D  DDD        DDDDDDD              L   DDDDDDDDDD       DDDDDD  DDDD     L  DDDDDDDD  DD  DDDDD   DDDD        DDDDDD     DD    DD     I   DDDD            D   DD   DDDDS DDD  DDDS ND    DDDDD VVDDDDDD   VDVDDDDDDDDDIDDDDDDDDD  DD  D   D   VVVDDVDD   D DDIDDDDD DDDDDDDEEED DDDDE  EE ELDDDE NDD WWWDDDHHD  MMIDD EDDD VDDLDDDDDLDD  DDDLDD   DDDDWWWDDDDDDMDDHWWWWW LLVWWD HHHHDDDHDDHHDI  MDDD F DD LLDDDD DDIDDDLDDDDDDDDDDEWWWDDMDWDDDTDWWWQQQHHNDDVDDD DDDD YY  VVDD    D  DWWHHDDHH DDDVLMMDDDDD  MMIEKKDD DD HVWWDWW    I  D DHD           DDDDDDDDDDDDDDDD     HHHHHHHHHHHHH  DHH             LLLLDDDDD SSSSSDDDDDDDDIIIVV   DDDDD     DDDDD     DDDDD   NNDDDDNDDDDDTTTTTTDDD          DDDDDDDDIIIII DHHHDDDDDDDD  HDDDD     DDDDDD E   DDDDDDDDDDDS DLNDDDHDD DD DD      E5B  EE
 TPPPPP   PP        PP   PPQPP     PPPPPPPPAAAPPPP   PP  PPPPP         EPPP       P  PPP        PPPPPPP              E   PPPPPPPPPP       PPPPPP  PPPP     Q  PPPPPPPP  PP  PPPPP   PPPP        PPPPPP     PP    PP     K   PPPP            P   PP   PPPPP PPP  PPPA EP    PPPPP DGPP  PPS  EPQPPPPPPPPPSPPPPPPPPP  PP  T   P   PPEPPEPP   P PPDPPPPPQIPPPPPPPPPP PPPPPT PP PPETEP STM PPPGGTEEP  PPEPPTPPPPTGPPPS  PPEGGTTGGRTPP   KKPPPPPPGGPTIPPPPPPPPP SEGPPT EEEEKPPEPPPPIE  PQPP  TTT PPPPPP PPPPPPPEEEPPPPSSPSPPPTTTPPPKRLQPPPPPPPPQPPPPPP PPVV EE  PPEE    P  PPPPPSSPPPPPLGTTTKKEKK  TT PTTPP PV PSPPPPP    D  P VKP           VMMMMMMMMLTTTQPP     EEEEEEEEEEEEEPPPPP             MMMMPPPPP TTTTTPPPPPLLLVVVPP   PPPPP     PPPPP     SSSSS   TTLLLLPTTTYYPPPPPPEEE          PPPPPPPLPPPPP TPPPTTTTPPPP  PPPPP     TTTLLL P   TTTTPAAIIIIP TTTTPPPPP LP PP       4     
 EYYYYY   YY        YY   YYPEE     IINNNYYYGGGYYAA   YY  EEGGG         ANNN       Y  YYY        IISSNNN            HHD   EEYYYYYTYY       YYYYYY  YYYY     P  YYYYYNNN  YY  NNNNN   YYYY        NNYYYY     YYHH  YY     P   YYAA            Y   TT   YYYYT EYY  YYFS AE    EEYYE ASYY  NND  DYSYYYYYYNNNPYYYYDENNN  NN  E   E   AASYYAYY   S SSSDDEEYGELEDFDDEEEY RRRREC ED EGVEAD TAT EEEVVEQQD  VVTEEQGHHHPPRRGE  EESAAPPAARAED   VVRREEEGVVAAKSEEKEEEEE DSPEET QQQQSVFERRQQKK  ATGG  ENT GGEEEE EESRRISLLLEEEEEEETEEEVVDCHNDSKTDEEDDDQQTRRANRRKEEED EE  DDVV    V  DEEQQNNDDFQQGSAEEQQQQQ  EEGFDDQQ NE EGDDNEE    S  Y EEH           HNNNNNNNNALLLDLL     SSSSSSSSSSSSSQQKSS             DDDDKKKKK KKKKKTTTTTSSSDDDSS   RRRRR     EEEEE     AAAAA   EEAAAASKKKRRIIIIIINNN          TTTTTTTEGGGGG LVVVEEEEVVVV  RQQQQGGGGGEEEAAA R   AAAAKNNQQQQM KSKKIEKTS VK AA       8     
 NSSSSS   TT        SS   SSSTT     QQTTTTTTTTTTTQQ   TT  TTTTT         STTT       S  TTT        RRTTTTT            SSA   TTTTTTTKSS       TTTTTT  TTSS     S  GGGSSTTT  SS  TTTTT   TTTT        TTSSGG     TTSS  GG     S   TTQQ            T   QQ   NNSSP TTT  TTSP TT    SSTTT TSSS  TTS  TTSTTTTTTTTTSTTTTTTTTT  TT  T   T   RRSSSTTT   T TTSTTTTSSTTTTSTTTTTT SSSSTS TT TTNTGT TTT SSSSSATTT  TTSNNTTTTTTSTTTT  SSSSSTTSSTSTS   TTTTSSSMSSTTTTNNTSSSSS TSASST TTTTTRSTTTTTTA  TTTT KSTTTSSTTTT SSTTTQTTTTTTTTNNTSSSSTTSTSSTTCTTSSSSSTTTTTTTTTCTTTT TT  TTTT    T  SSSTTDDTTKTTTSEEESSQTT  EESKEETT TS TITTTSS    S  T HSS           TTTTTTTTTTTTTTSS     SSSSSSSSSSSSSTTSTT             VVVVTTTTT TTTTTTTTTTTTTKKKTT   SSSSS     TTTTT     TTTTT   TTKKKKTAAASSNNNNNNGGG          TTTTTTTSTTTTT TTTTTTTTTTTT  TRRRRTTTTTTTTKKK Q   RRRRTSSRRRRR KPTSSTTSS AK TT       8     
 LGGGGG   GG        EE   GGGGG     GGHHHGGGGGGGGGG   GG  GGQQQ         KHHH       E  GGG        GGMMHHH            GGK   GGGGGGGQGG       GGGGEE  GGEE     G  GGGEEHHH  GG  HHHHH   GGGG        HHGGGG     EEGG  GG     N   GGGG            G   GG   GGGGK NKK  GGGK RG    GGGGG KKGG  EEP  ESKNNNNNNQQQQGGGGGNLLL  KK  L   G   GGKGGKNN   G QQQGGSSGQLEGGGGGGGGA AAAAGQ GG GDDIEG GDD GGGDDVGGD  GGKEENNGGGNRNNDG  YYKDDNNDDGGGK   GGGGGGGQDDGDGQCCAGGGGG NKGGGQ GGGGDSGSGGKKGD  GGGG GRDEDQQNGEE CCGGGGGGGGEEEECCGGGGGGGNSGANGGGGGGGGGGGGGGGAGGGCCGD GG  GGGG    G  KGGGGGGGGGCCMGEGGNNDLL  GGLRGGAA AG KGSSEGG    Q  G GGA GK        DGGGGGGGGQAAAGGG     NNNNNNNNNNNNNQQGKK    RRRR     NNNNAAAAAKGGGGGGGGGGIIIKKKGG   GGGGG     GGGGG     SSSSS   SSAAAANNNNNNKKKKKKKKK          GGGGGGGSDDDDDRGEEEDDDDQQQQ  QGGGGGGGGGNNNAAAGG   DDDDDAANNNNR GKGERGGDA GS GG       8     
 EKKSSS   QQ        QQ   SSAKK     TTEEEEEEEEEQQVV   EE  KKEEE         QEEE       Q  EEE        VVEEEEE            SSE   KKEEEEEESS       EEEEQQ  EEKK     R  TTTQQEEE  SS  EEEEE   DDDD        EEKKEE     QQSS  EE     Q   EEGG            S   VV   EEKKE RGG  EEKE EN    KKSSN EEKKKKEEP  EERQQQQQQEEENDDKKKKQQQ  EE  E   K   EEDKKEQQ   Q EEEKKKKKTEENKKLLKKKQ QQQQKG KK KNRECR ETN EEERREQQL  EEGDDEKKKKQ QQKKKKRREKKQQKKTEKA   DDHHEEEEKKKTAERRKEEEEE EESEES KKQQSVNQHHEEAN  EEKK KGTSQEERKLL TTEHHMEEEELLLLKKKQEEEQQEEEETEREEEEEEERREHHEEHHRMMES EE  EETT    N  AEERRKKEEKEEEEDEEEENEE  EEGEEERR DA EEEEEEE    E  D QDH ER        SNNNNNNNNERRRRQQ     EEEEEEEEEEEEEKKNKK    EEEE     AAAAEEEEERKKKKKEEEEEEEEAAA     QQQQQ     TTTTT     KKKKK   QQKKKKERRRRRAAAAAAYYY          EEEEEEEHRRRRRQKRRRQQQQQQQQ  EHHHHKKKKKKKKKKKED   QQQQNDDRRRRE EQEEREEER EL FK       4     
 KLLTTT   QQ        KK   TTKEE     RRNNNQQQKKKSSLL   QQ  EENNN         KNNN       K  QQQ        RRKKNNN            TTK   EEQQQQQKTT       QQQQPP  QQKK     R  KKKKKNNN  TT  NNNNN   QQQQ        NNLLKK     TTTT  KK     K   QQRR            T   RR   QQVVK EQQ  QQTK KI    EEKKI RPLLPPNNK  RKKKKKKKKYYYVTTVVEERRR  NN  K   I   KKRIIKMM   L QQTEEEEVRKSIETEEDDDR PPPPDK DD DIIKTD KKK IIIVVKKKR  IIKGGKLSSSKKKKTDPPIIKVVKKVVQRDP   AARRIIISVVTKEVIITIIIII RI IIR TTKKKRKKRRPPEK  QVPP KPCRARRQDNN TTCRRRHTTTNNNNIIDKIIIRRKRIKCVSVIIIMMMTTVRRHRRRKVVVK NN  KKRR    T  PIITTTTRRKSSTTVKKTTATT  KKKVKKVV KV THIINII    T  RVIMV KQ        CVVVVVVVVSEEEQKK     FFFFFFFFFFFFFQQSPP    PPPP     PPPPTTTTTVSSSSSYYYYYKKKAAA     LLLLL     IIIII     LLLLL   NNLLLLSTTTKKPPPPPPEEE       PPPYYYYYYYTLLLLLPPKKKLLLLVVVV  AVVVVVVVVVSSSLLLFR   LLLLKKKIIIIK DSNEKVIKH SR IV      E4   EE
 IIIIII   II        II   IIAMM     VVLLLIIIIIIVVVV   II  MMLLL         MLLL       I  III        VVVVLLL            MMV   MMIIIIIMII       IIIIII  IIII     L  LLLIILLL  II  LLLLL   IIII        LLIILL     IIMM  LL     M   IIVV            I   VV   IIIIY MII  IIVH LI    MMIII LLIIMMLLI  LILIIIIIIVVVLIIIIMMAAA  VV  I   I   MMLIIMII   V LLMMMMMLLIIIMMMMLMLM LLLLMM LM MIMILM MCC LLLLLVLLA  IIMVVMILLLVMLLILMMVVMLLMMLLYIML   LLLLLLLLLLVILMVVLLLLLL ILVLLM LLLLCVILLLLLMV  FFLL LLFMMLLMLVV IILLLVLLLLIIIIVVMLLLLLLLVFVLLIHFLLLLLLLLLLLLLLIVVFI LL  IILL    L  LLLLLVVVVVLLFVTLLLLLLL  LLMLLLVV LM ILFFLMM    M  ILRMV FV        VHHHHHHHHFMMMMFF     VVVVVVVVVVVVVMMMLL    IIII     IIIIVVVVVMAAAAALLLLLVVVIIIYY   LLLLLLLLLLIIIII     YYYYY   LLVVVVLLLLLLLLLLLLLLL       IIIYYYYYYYMTTTTTLIIIILLLLKKKK  LLLLLIIIIIIIIVVVIV   LLLLIFFLLLLL ILLIIVLLLMLL ED      E5BB EE
 SSSSSS   SS        SS   SSSSS     AATTTSSSSSSSSAA   SS  SSSSS         STTT       S  SSS        AATTTTT            SST   SSSSSSSTSS       SSSSSS  SSSS     S  PPPSSTTT  SS  TTTTT   SSSS        TTSSAA     SSSS  AA     S   SSSS            S   AA   SSSST TSS  SSSS SS    SSSSS SNSSNNTTS  SSSSSSSSSTTTSSSSSSSTTT  TT  T   S   SSSSSPSS   S TTSSSSSSPTSSTSSSSSSS SSSSSP SS SSPTPS SNS PPPTTSSSS  SSSTTPSSSSSSTTSSNNPPSTTSSKKDSST   TTTTPPPSTTSSSSPPSPPPPP TSTPPS LLLLTPSLTTSSTS  TSSS SSSSPSSTSSS PPTTTATSSSSSSSPPSTSSSSSSSPSSSSSPPPPPPTTSTTTSTTTPPSS TTPPSSPP    S  TPPTTTTSSTTTPSNLLTTPTT  LLHSLLPP SS SNPPTPP    S  SSSTP PS        NSSSSSSSSLSSSTRRSS   DDDDDDDDDDDDDSSSPP    TTTTTTTTTSSSSPPPPPKNNNNNDDDDDTTTSSSHH   TTTTTTTTTTSSSSS     SSSSS   SSRRRRPSSSNNNNNNNNNNN       DDDDDDDDDDTSSSSSTSTTTPPPPNNNNSSSNNNNHHHHHPPPRRRDS   PPPPTSSNNNNS PRTSTSTTSPIS TT      E0    E
 ILLLLL   LL        LL   LLIVV     PPYYYLLLLLLLLPP   LL  VVYYY         IYYY       I  LLL        PPYYYYY            LLI   VVLLLLLILL       LLLLLL  LLLL     L  LLLLLYYY  LL  YYYYY   LLLL        YYLLLL     LLLL  LL     I   LLLL            V   PP   LLLLL VLL  LLVL IL    VVLLL VLLLLLYYI   LILLLLLLYYYILLLLVVYYY  YY  I   L   IIILLIVV   L YYFVVVVVIIYLVVVVPPPV VVVVPF PP PLFIIP III IIILLILLY  LLFYYLLVVVIFVVLPLLYYFLLIILLILPV   CCVVIIIYLLLIALYYVIIIII VFIIIV LLLLIPLLVVFFSI  LIVV VVVVIIIIPYY YYLAAPLVVVYYYYYYPVIIIIIILALVIIIIIIIIIVVVVVLLVVIYYVV LLVVLLCC    L  VIIVVVVAAITTVLLPPLLVLL  PPVLPPYY LV LLVVYII    F  LVLVY LL        VFFFFFFFFIFFFILLLL   IIIIIIIIIIIIILLLII    FFFFLLLLLIIIILLLLLALLLLLLLLLLLLLLLLII   VVVVVFFFFFFFFFF     LLLLL   FFLLLLIFFFLLIIIIIILLL       LLLLLLLLLLILLLLLFLLLLLLLLIIIILLLLLLLLLLLLIIILLLLILLLLLLLVLLIIIIILIVFLQFVVPVKR KV      H1BB HH
 TFFFFF   FF        FF   FFAYY     EELLLFFFYYYFFEE   FF  YYGGG         YLLL       F  FFF        EESSLLL            WWY   YYFFFFFYFF       FFFFFF  FFFF     YTTFFFFFMMM  FF  LLLLL   FFFF        LLFFFF     FFWW  FF     Y   FFDD            W   EE   FFFFL QFF  FFSV YF    YYFFF YYFFWWLLY   FYFFFFFFLLLYFFFFQQKKK  SS  S   F   YYYFFDFF   FKQQYRRYYGTSAFRARRYYYQ FFFFYT YY YFYTYY QRK TTTSSTTTV  FFAMMFFFFFYTKKFYWWSSTSSYYSSNLYL   AADDTTTGSSFQYYSSSTTTTT LVTTTR XXNNREYNEESSYN  HFFF FLRRYYYRYRR SSQEEEQAAAGGGGSSYEAAADDYMSNRFLFSTTIIIAAFDDQEDDLSSFT GGVVSSAA    F  VTTAASSFFWEEFDEDDPPVPP  DDSSDDSS RC PNSSLVV    Y  FSKPT QN        RIIIIIIIISEEEASSEE   DDDDDDDDDDDDDKKQKK    DDDDAAAAAQQQQDDDDDNLLLLLIIIIIRRRQQQYY   GGGGGTTTTTNNNNNFFFFFSSSSS   NNPPPPQNNNVVLLLLLLIII       RRRAAAAAAAKKKKKKDSNNNDDDDNNNNPPSKKKKEEEEETTTPPPQTSSSNNNNIRRNNNNMSQENDSHGTSSEQ YN      H5   HH
 EQQQQQ   QQ        QQ   QQQEE     LLQQQQQQKKKQQPP   QQ  EEQQQ         DQQQ       Q  QQQ        LLEEQQQ            EED   EEQQQQQQQQ       QQQQQQ  QQQQ     AQQQQQQQQQQ  QQ  QQQQQ   QQQQ        QQQQQQ     QQEE  QQ     E   QQLL            Q   VV   QQQQE EEE  QQEE QQ    EEQQQ QQQQDDQQQ  KQEQQQQQQQQQEQQQQEEQQQ  QQ  E   Q   EEQQQAQQ   QQQQQEEEEQEEHQEEEEEEEE EEEEEE EE EQQEQE ETT DDDQQEEET  QQSSSEEEEEQEEEQEDDEESQQQQQQDKEQ   QQEEDDDQQQQNEDEEQDDDDD KLEDDS EEEESIQEEEEEET  KQQQ QEASREEEDAA EEKEELNEEEAAAAEEDEDDDEEQDSDMQRQTDDDDDQQQEEKEEEREEQS EEAAEEEE    E  QDDQQEEEEEDDQIREEEEREE  EEGEEEEE EC EKTTQEE    Q  QADEE ED        SDDDDDDDDDEEEQEEKK   EEEEEEEEEEEEEEESQQ    QQQQEEEEERRRRTTTTTEAAAAAEEEEEEEERRREE   EEEEEEEEEEDDDDDDDDDDAAAAA   EEEEEEREEEEEEEEEEERRR       EEEEEEEEEEEEEEEEQELLLVVVVKKKKEEEQQQQPPPPPEEEEEESEDDDVVVVQDDKKKKQDVTEDEDEQERQE  G      H6   HH
 GAAAAA   AA        AA   AAAAA     AALLLAAAAAAAAAA   AA  AALLL         ALLL       A  AAA        AALLLLL            VVA   AAAAAAAAAA       AAAAAA  AAAA     AAAAAAAALLL  AA  LLLLL   AAAA        LLAAAA     AAVV  AA     A   AAAA            A   AA   AAAAA AAA  AAAA AA    AAAAA AAAAIILLA  VAAAAAAAALLLAAAAAAALLL  LL  A   A   AAAAAAAA   AVLLAAAAAAAAMAAAAAAAAA AAAAAA AA AAAAAA AAA AAAAAAVVL  AAAMMGAAAAAAAAAAVVLLAAAAAAACAAS   AAAAAAALAAAAAALLAAAAAA AAAAAA AAAAAAAAAAAAAA  ASAA AAAAAAAAALL LLAAAAAAAALLLLLLAAAAAAAAISLAAASSAAAAAAAAAAALAAAFFSA AAAAGGAA    A  SAAAAAAAAIVVAAAAAAAAAA  AAAAAALL LS ALSSLAA    A  AAAAL AL        AAAAAAAAAQAAAACCAA   AAAAAAAAAAAAASSAAA    AAAAAAAAAAAAAAAAAAAAAAAAAAAAASSSAAAAA   AAAAAAAAAALLLLLLLLLLAAAAA   AAAAAAAAAAAAAAAAAAAAA       AAASSSSSSSACCCCCAAAAAAAAAAAAAVVAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAVAAAAIA  E      H6BBBHH
 IMMMMM   MM        MM   MMVYY     CCLLLMMMMMMLLCC   MM  YYLLL         MLLL       M  MMM        CCRRLLL            MMM   YYMMMMMMMM       MMMMMM  MMMM     MLLIIIMMLLL  MM  LLLKK   MMMM        LLMMII     MMMM  II     M   MMYY            M   CC   MMMMK YVV  MMIK MM    YYMMM MMMMMMKKM  SMMMMMMMMQQQKLLMMYYLLL  FF  M   M   MMMMMIMM   IVMMMYYYYCRVLMYMYYYYYK VVVVYK YY YIMVMY SVV LLLVVLIIK  IIAKKVIMMMSKCCIYVVVVAIISSIILSYI   VVVVLLLLTTIVFSVVVLLLLL SAKLLM VVVVIVMIVVIIYM  FVMM MISLMRRYYII VVFVVCFVVVKKKKIIYLLLLVVMILMMVAILLLLLLMMVVVFLVVALLVV VVIILLVV    M  ILLMMLLLLIIIARAVVVVMVV  VVKMVVVV RV IFLLMLL    MV MMAVI AF        MIIIIIIIIKEEEITTII   IIIIIIIIIIIIIIIIII    AAAAIIIIIIIIIIIIIILVVVVVIIIIIIIIIIIEE   IIIIIVVVVVVVVVVVVVVVLLLLL   VVFFFFMLLLVVIIIIIIVVV       AAAIIIIIIILIIIIIVIIIILLLLIIIILLLAAAAIIIIIIIIFFFRVIIIVVVVILLVVVVIIMIVIILIAITLF  V      H6BB HH
 EKKKKK   KK        KK   KKRRR     QQEEEKKKKKKKKHH   QQ  RRAAA         KEEE       K  QQQ        QQKKEEE            QQR   RRQQQQQWKK       QQQQRR  QQKK     KKKGGGKKEEE  KK  EEEEE   QQQQ        EEKKGG     KKQQ  GG     K   QQQQ            G   QQ   QQKKR NNN  QQKR KN    QQKKN KKKKNNEEK  FKRQQQQQQKKKTKKKKNKEEE  DD  R   N   WWKKKKQQ   EFEEKHHRRRSRKKHKHHKKKQ KKKKKH KK KEKRKQ RIA EEEQQNDDK  EEKRRREKKKKKAAEKNNKKQKKKKKKKRKD   KKRRKKKAQQEKQRKKQEEEEE RKREET AAAATQRARRKKRK  QLKK EEVTKGGDLEE KKQRRQQKKKEEEEKKIAEEENNKQQQVLHLHEEEEERRLRRQDRRHKKVH AAEEAARR    N  DEERRPPQQNEEQHEVVAAEAA  AAKAAANN EN KQQQEQQ    KL TAQKN LK        SDDDDDDDDAKKKEEEQQ   KKKKKKKKKKKKKIIEEE    EEEEDDDDDHHHHEEEEEESSSSSHHHHHEEEHHHRR   NNNNNRRRRRNNNNNRRRRREEEEE   EERRRRLDDDRRSSSSSSAAA       RRRQQQQQQQNTTTTTESAAAEEEEDDDDQQAQQQQEEEEEEEERRRESAAAEEEEDGGEEEEEASTDERERERAES  E      H5   HH
 RKKKKK   KK        KK   KKDKK     QQRRRKKKKKKKKQQ   KK  KKRRR    RR   NRRR       K  KKKQQ      QQRRRRR  EE        SSR   KKKKRRRKKK       KKRRKK  RRKK     QKKKKKKKRRR  KK  RRRKK   RRRR        RRKKKK     KKSS  KK     K   KKKK            K   QQ   RRKKK KQQ  KKKK IK    KKKKK KRKKSSRRN  RKKKKKKKKRRRKKKKKKKKKK  RR  R   K   KKKKKKKK   KRKKKRRKKQKRRKRKRRRRRK KKKKRK GR RKERNR AKKQQQQLLREEQ  NNQRRRRKKKEMRRRRSSKKKLLEELLRRRR   LLHHQQQRLLKRRKKKEQQQQQ KREQQR CCQQRLKEHHLLKL  RKKK EKRRERRKQRR KKRHHQRAAAKKKKKKQEQQQRRDRQRRREKQQQQQQEERHHQRHHEKKKRRKKNNKKLL    K  RQQEEQQEESEEHKAQQLLTLL  QQRRQQQQ RH LRQQRQQ    KK KHTSK QA        RRRRRRRRRTWWWQKKQQ   LLLLLLLLLLLLLKKQDD    SSSSRRRRRQQQQRRRRRTEEEEESSSSSKKKQQQKK   LLLLLQQQQQLLLLLEEEEESSSSS   AAKKKKEAAAEEVVVVVVKKK       RRRNNNNNNNQLLLLLSREEEKKKKDDDDRRQRRRRRRRRREEEKKKRQHHHQQQQTKKTTTTAHQRRKRLLRRERK  R      H1   HH
 GGGGGG   DD        DD   GGGGG     GGCCCGGGGGGGGGG   DD  GGCCC    GG   NCCC       E  DDDGG      GGCCCCC  GG        DDG   GGDDDDDGGG       DDGGDD  DDDD     QGGEEEDDCCC  GG  CCCCC   DDDD        CCGGEE     DDDDGGKK     K   DDGG            G   GG   DDDDQGGEE  GGNKGGE    GGEEE GGGGNNCCG  GDRDDDDDDCCCGDDDDGCCCC  CC  G   E   GGNDDNDD   EGCCDEEGGGNNCEENEEGGGG GGGGGK GG GGGGGG GKNGGGGGGGGGC  SSRCCKGAAAKKGGGNNNCCIGGKKGGGNGG   GGNNGGGCGGGNNGCCNGGGGG NKNGGK GGGGKGGGNNGGNG  NGGG RRKGGGGGGCC CCNNNSNAAACCCCCCGGGGGDDTSECKGGGEGGGGGNNGNNNTNNGCCGNGGGGGDDGG    G  GGGNNGGGGEGGGGGGGKKGKK  GGMHGGGG CG DNGGCGG    DG EGGGG GG        KDDDDDDDDSGGGGKKGG   EEEEEEEEEEEEEGGRNN    KKKKKKKKKGGGGKKKKKGGGGGGGGGGGPPPGGGGG   RRRRRGGGGGKKKKKKKKKKGGGGG   GGGGGGGGGGRRGGGGGGGGG       GGGGGGGGGGGKKKKKSKEEEKKKKGGGGEEGGGGGKKKKKNNNGGGGGGGGQQQQGGGEEEEGGGTGGHGRNNGFR GG       4     
 ILLLLL   LL        LL   LLLLL     LLIIILLLMMMLLLL   LL  LLVVV    LL   LVVV       L  LLLII      LLIIVVV  LL        LLL   LLLLLLLILL       LLCCLL  LLLL     LLLIIILLVVV  LL  IIIII   LLLL        VVLLVV     LLLLLLVV     L   LLLL            L   LL   LLLLLLLLL  FFLLILL    LLLLL ILLLLLKKQ  LLIVVVVVVIIILLLLLLLRRR  VV  I   L   VVMLLLLL   LLTTLLLLLHLIKLLLLLIIIL LLLLVL II IVLLLV LMMLIIIKKLLLK  LLVKKVLLLLKIVVLLLLKKIKKKKKKVLIL   EELLIIIVKKLMLLKKLLLLII LILLLL VVIIILLLLLLLFI  LLLL IILLLLLYLLL RRLLLLLKKKMMMMKKLVIIILLVILVMLLFMIIIIILLLLLLVLLLKKLLLLLIIIIKK    Y  LIILLLLIIYLLLLLVVKKLWW  VVLLIIKK VI LLMMVVV    LL LLLQK LV        LLLLLLLLLIVVVYIIKK   IIIIIIIIIIIIILLVFF    CCCCLLLLLLLLLFFFFFLTTTTTFFFFFLLLLLLLL   IIIIIFFFFFVVVVVFFFFFLLLLL   VVLLLLKVVVLLIIIIIIIIIIIIIIIIYYYFFFFFFFLIIIIILILLLMMMMIIIIFFVIIIIFFFFFFFFLLLLLLLLLLLLIIIIIIIVLLMVILIVILKFL QV       7B    
 VIIIII   II        II   IILII     LLEEEIIIIIIIILL   II  IITTT    RR   LRRR       I  IIIRR      LLVVRRR  RR        IIL   IIIIIIILII       IILLII  IIII     LRRVVVIIRRR  VV  HHHTT   IIII        RRIIVV     IIIIRRVV     L   IILL            I   LL   IIVVLRIII  FFIIRVI    IIVVI IIIILLIII  RILIIIIIITTTLIIIIIIRRR  TT  V   I   LLIVVLVV   IRKKMIIIIILVVIIVIIIIII LLLLILLII IVLVLI IVLRVVVLLVMMALLVVIVV IIIIILVVVILLIIIVVIIVVIVIL   VVIIVVVTVVIIIIIIIVVVVV VMIVVI VVVVLLLVIIVVII  IIII LIIILLLIITT IIIIILIVVVIIIIIIIIIIIVVLLIPIVIIIVVIIIFFIIIIIIIIIIIIRIIIIIILL    V  LVVFFIIIILMMILILLVVIVV  LLMVLLVV AI VIIITII    ML IILVI VV        ILLLLLLLLIIIIIVVFF   FFFFFFFFFFFFFFFIII    LLLLFFFFFFFFFIIIIIIIIIIIIIIIIIIIYYYII   LLLLLIIIIIFFFFFLLLLLIIIII   IIMMMMIIIIIILLLLLLIIILLLLLLLVVVIIIIIIIIIIIIILLIIIMMMMVVVVYYVLLLLIIIIIIIIMMMILVVVMMMMIIIIIIILVIIIILFLLLIIL IL       8B    
 DLLVVV   VV        PP   VVPDD     DDDDDVVVEEEPPDD   VV  DDDDD    KK   LDDD       P  VVVQQ      DDDDDDD  HH        PPR   DDVVVVVR         VVSSPP  VVPP     GGGDDDPPDDD  LL  DDDEE   VVVV        DDLLDD     PPPPRREE     S   VVDD            D   DD   VVPPTDDVV  DDDTKRE    DDLLE RTLLPPDDK  RVRPPPPPPDDDSVVPPDDDDD  DD  D   E   RRRLLTPP   ERDDRDDDDDSDGEDDDDDDDD DDDDDSNDD DEMDRD RDDHSSSDDDDDDPPEEEDD EDDDTSDDEDPPDDDDDTTDDDDDE   DDDDSSSDDDEDDPDDPSSSSS DGVSSD PPPPDNISDDSSDK  SDDD DNDDQRRDDEE DDSDDDSDDDDDDDDDDDSSSAAQQTHDDDDTSSSSSPPDDDSHDDDDDDDKEESSDDDD    T  ESSPPNNNNTDDDPSPPDDRDD  PPSVPPDD HD ASSSDSS    RP VTDDD ETDDDDDDDDDGGGGGGGGDDDDDDDDD   DDDDDDDDDDDDDNNDDD    DDDDDDDDDDDDDTTTTTD     DDDDDDDDKKKDD   DDDDDDDDDDDDDDDDDDDDTTTTT   IIDDDDP   DDDDDDDDDDDSSSSSSSVVVDDDDDDDDNNNNNDDNNNDDDDDDDDTTTDDDDTTTTT   DDDDDDDDDDDDNSSDDDDDDKR NDDDDDPDD DN       8     
 SKKRRR   RR        SS   RRTHH     QQPPPRRRKKKRRRR   RR  HHPPP    QQ   PPPP  RR   S  RRRQQ      QQPPPPP  KK        QQP   HHRRRRRPLL       RRDDAA  RRSS     PHHRRRAAPPPRRRR  SSSPP   KKKK        PPKKPP     AAQQQQRR   RRP   RREE            Q   QQ   HHEEPTYRR  PPRPDPK    HHRRK PQKKEEEEP  QKPKKKKKKKKKPKKEEYYPPP  KK  T   K   PPPEELKK   KGPPPYYHHKPSKKYRYYRRRK KKKKRPQRR RRRSPR KPPTTTTFFSEELEEKKRPP KKKKPSKKKREEIIKFFPPFFQRRR   LLQQTTTPFFESKMIIKTTTTT RKKAAP SSSSENKSQQPPKT  ASKK RELAPPPSRPP IISQQQPPPPAAAAVVRGTTTSSQENQTYRYNTTTTTKKYQQSEQQRIIYPQSSEEAAPP    E  KTTKKKKTTEEEQMRGGPPEPP  GGPEGGII GQ PANNPGG    PG RQSPI PEKKKKKKKKTDDDDDDDDQEEETDDPP   SSSSSSSSSSSSSPPPAA    LLLLPPPPPDDDDPPPPPEPPPPPPPPPPRRRDDD          EEEEEPPPPPPPPPPPPPPP   PPTTTTLVVVPPSSSSSSPPPSSSSSSSPPPPPPPPPPPPPPPPLPPPPTTTTVVVVPPPPPPPPPPPP   TTTLTSSSRRRRPPPPPPPG VE QMPVLLMLP PV       7     
 IDDEEE   EE        EE   EEGQQ     EEEEEEEEEEEEEEE   DD  QQEEE    VV   GDDD  VV   E  DDDII      EEAAEEE  VV        EES   QQDDDDDGKK       DDDDEE  DDEE     GVVAAAEEDDDVVDD  EEESS   NNNN        EEDDPP     EEEEVVTT   VVG   DDEE            N   EE   DDDDEVDSS  NNEEVGG    QQEEG GEDDQQGGE  VDGEEEEEEKKKEDDDDDDNNN  KK  I   G   GGGDDGDD   GVEEGDDQQEEIDGDEDDGCGQ KKKKSEEGD GGGIGC GMIVEEEAAIKKNEEGGSHH GKKKGDEEGEQQEEMAAGGAARVGE   LLDDEEEEAAGISGEEDEEEEE IADEED HHHHEADHDDEENG  SDNN YRTDYGGQNHH EESDDETVVVHHHHEEPNEEERRNNEETDEDEEEEEEDDEDDAKDDEEEDHVRRNNKKLLDD  S  ADDDDNNEEERRDDRHHAAEVVDDHHERHHKK DI DVDDQEE    GH DEDIE HSKKKKKKKKNGGGGGGGG KKKGRREE   SSSSSSSSSSSSSYYNII    QQQQAAAAAKKKKEEEEEESSSSSAAAAANNNQQQ          DDDDDDDDDDEEEEENNNNN   NNQQQQILLLKKDDDDDDVVVLLLLLLLSSSAAAAAAADNNNNNS EEEKKKKDDDDSSDEEEEEEEEE   QQQKNAAAHHHHKNNEEEEN TG TEDRHDFVK KD       7     
 THHHHH   HH        EE   HHLTT     TTTTTHHHEEEQQTT   HH  TTTTT    SS   VTTT  TT   E  HHHTT      TTSSTTT  TT        RRT   TTHHHHHTMM       HHTTEE  HHEE     VSSLLLEETTTTTHH  TTTTT   HHHH        TTHHLL     EERRTTLL   TTT   HHTT            E   TT   HHYYNTTHH  TTTSTTH    TTHHH TLHHEETTV  SHTYYYYYYTTTMHHYYTTTTT  TT  T   H   TTTYYTYY   HSTTPTTTTTST HTTTTQQQF TTTTQSTQQ QHTTTQ TTTTLLLPPTLLTAAHHSTTTHTTTTSDDHQEESSIAATTAASTQE   PPMMLLLTSSHTIFSSALLLLL TLSLLT TTTTTIHTMMLLTT  LTTT KITTSTTTQTT SSLMMTLPPPTTTTSSQTLLLIITTLTTTTTLLLLLLVVTLLLTLLTSSTTSMMTTTTPPTT  R  ELLVVVVLLQLLTLLTTPPVPPTTTTSHTTTT TT LLLLTLL    PT HETPT TTTTTTTTTTTLLLLLLLLT   NSSTT   TTTTTTTTTTTTTGGLEE    TTTTTTTTTTTTTGGGGGTTTTTTTTTTT   TTT          RRRRR     TTTTTMMMMM     TTTTTSSSNNNNNNNNKKKTTTTTTTNNNTTTTTTT SSSSST TTTQQQQRRRRTT SSSSGGGGG   TTTST   VVVVLKKSSSSL FR ETHTSSIAK SS       5B    
 GGGGGG   GG        AA   GGGYY     WWGGGGGGAAAGGWW   GG  YYGGG    AA   AGGG  AA   A  GGGAA      WWGGGGG  PP        AAA   YYGGGGGANN       GGVVAA  GGAA     AVVGGGAAGGGAAGG  GGGGG   GGGG        GGGGGG     AAAAAAGG   AAA   GGGG            G   WW   GGAATPYGG  HHGTAAG    YYAAG AAGGRRGGA  AGTGGGGGGGGGAGGAAYFGGG  GG  G   G   AAAAAGGG   GAGGAFFYYTAGGGFGFFYYYE GGGGYAQYY YGTGTY AAGAAAATTALLGTTGGAGGAGGGGAAEEGYRRGGAAAAATTLAYA   TTAAAAAGTTGAYAGGGAAAAA AAAAAG AAAAGLGAAAKKYG  FGTT AGAAAAAFYGG GGFAAWYAAAGGGGGGYAAAAAAGGAGAGMGAAAAAAGGGAAFSAAMGGGAAAAGGYYAALL  G  VAAGGTTAARLLCSCAAAAGAAEEAAAAAAGG GG KFAAGSS    AA AGVAG L GGGGGGGGAFFFFFFFFL   VGGGG   GGGGGGGGGGGGGTTVLL    GGGGGGGGGGGGGAAAAAAAAAAATTTTT   GGG          QQQQQ     GGGGGGGGGG   AASSSSISSSRR      GGGIIIIIIIFFFAAAAAAA AAAAAG SSSVVVVGGGGGG GGGGAAAAA   SSSIG   TTTTGKKSSSSG SV G VGSGGGS GG      H1BB HH
 QIIIII   II        LL   IIQLL     RRLLLIIIMMMLLHH   II  LLLLL    SS   LLLL  CC   L  IIISS      HHFFLLL  SS        QQT   LLIIIIILRR       LLVVLL  IILL     LSS   LLLLLHHII  LLLLL   IIII        LLIIKK     LLQQSSYY   HHL   LLHH            F   LL   IIMMVGMII  EEMVELI    IIIII FVIIQQLLL  SIMIIIIIILLLLIILLMVLLL  LL  Q   I   LLFLLMLL   IQLLLLLLLIIQLILMLLLLLD IIIILITLL LILQLL FQQRHHHLLQHHLLLIIVLL ILLLMDSSIIQQQQLLLLLLLDLIV   LLCCHHHLLLIQLAQQFHHHHH LLMHHL VVVVQQIVCCRRIL  SILL KLQLLLLLILL WWSCCCALLLLLLLQQLHYYYLLLLSLQIFVFHHRRRLLICCSLCCFQQIVSIILLAALLEE  I  IHHLLEEMMIQQHQQVVLLLVVLLVVDIVVQQ LL RSQQLRR    LV VLVLQ R LLLLLLLLQKKKKKKKKH   ELLKK   KKKKKKKKKKKKKTTKVV    LLLLLLLLLKKKKLLLLLEVVVVVLLLLL   KKK          LLLLL     LLLLLFFFFF   EEKKKKKRRRTT      VVVKKKKKKKPPPIIIIIII VVVVVK LLLTTTTLLLLKK QQQQLLLLL   KKKVR   HHHHLIINNNNE SD K LRTVEEL  L      H4   HH
 RRRRRR   RR        KK   RRREE     GGYYYRRRRRRRRKK   RR  EEAAA    DD   RYYY  QQ   K  RRREE      SSLLYYY  QQ        LLL   EERRRRRVVV       RRLLRR  RRRR     AEERRRRRYYYQQRR  HHHCC   RRRR        YYRRGG     RRLLEERR   QQV   RRSS            L   SS   RRKKLEERR  NNRMDER    EEPPR ESRRKKCCN  ERIRRRRRRQQQIRRRREECCC  KK  R   R   VVEKKVRR   RQLLNDDEERMRFRERDDQQQI RRRRQMRQQ QREREQ EKKQKKKNNRNNLNNRRGLL RRRRVMKKRQKKRRAKKIIKKQRQS   RRAAKKKAKKRKEQRRRKKKKK RAKKKK KKKKKFRKAAEEEV  KRRR KKKKEVVEKQQ RRKAAGKRRRHHHHRRHGEEEVVARKRRRRRKKKNNNRRRTTKRTTRRRAMDKKKKMMRRKK  R  HQQRRNNAAEKKVKKKKRRRRRAAKKFRKKRR RS EKKKRNNR   NK RRRRR E VVVVVVVVKLLLLLLLLE   ALL     VVVVVVVVVVVVVVVIAA    TTTTKKKKK    SSSSSIIIIIIPPPPP                     RRRRRRRRRRTTTTT   RRLLLLRRRRII         DDDDDDDLLLAAAAAAA VVVVVF VVVHHHHIIIIVV LLLLLLLLL   LLLRV   SSSSSRRKKKKL RV Y VIY KSR SK      H5   HH
 LLLLLL   LL        LL   LLLLL     LLMMMLLLMMMLLLL   LL  LLFFF    LL   LMMM  LL   L  LLLLL      LLLLLLL  LL        MML   LLLLLLLLLL       LLIILL  LLLL     LLLKKKLLMMMLLLL  LLLLL   LLLL        LLLLWW     LLMMLLWW   LLL   LLLL            L   LL   LLMMLLLLL  LLLLLLL    LLIIL LLLLLLLLL  LLLLLLLLLLLLLLLLLLLYYY  LL  L   L   LLLMMLLL   LLIIMLLLLLLLLLLLLLLLLL LLLLLL LL LLLLLL LLLLIIIIILVVLIILLLLL LLLLLLLLLLLLYYFVVLLVVYCLL   VVLLIIIFVVLLLLYYCIIIII CFLIIL VVLLLLLLIIIILL  LLLL IVLLLLLLLLL YYLIILLLLLLLLLYYLIIIIIILLILLLLLIIIIIICCLLLVFLLLYYLLLVVIILLLLLL  L  LIICCLLLLLVVLLLLLLLILLKKLLILLLFF LL ILIILIIF   MI MILVF I MMMMMMMMLLLLLLLLLL   MLL     LLLLLLLLLLLLLLLTAA    YYYYLLLLL    LLLLLL     LLLLL                     VVVVVVVVVVLLLLL   VVCCCCRLLLQQ         NNNNNNNSSSNNNNNNN      L KKKSSSSVVVVLL LLLLLLLLL   CCCML   LLLLFLLLLLLV KQIY LAR LLL LY      H7BB HH
 LLLLLL   LL        LL   LLLSS     SSLLLLLLLLLLLSS   LL  SSLLL    FF   LLLL  RR   LLLLLLLLLLL   SSLLLLL  LL        AAL   SSLLLLLLQQ       LLAALL  LLLL     LFFWWWLLLLLLLLL  LLLLL   LLLL        LLLLLL     LLAAFFLL   LLL   LLSS            L   LL   LLLLLLAMM  TTLLLLL    SSLLL LLLLLLLLL   LLLLLLLLLLLLLLLLSSLLL  LL  L   L   LLLLLLLL   LLLLLSSSSLLLLLSLSSQQQL LLLLLL QQ QLLLLQ LLLVLLLLLLLLLLLLLLLL LLLLLLFFLQLLLLLLLLLLLRLQL   LLLLLLLLLLLFSLLLILLLLL LLMLLL MMMMLHLMLLQQSL  LLLL LLLLLLLASLL LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLFMMAAQQLLLLLLL  LLLLLLLLLILLL  MMLLLLLLLMMLLMMLL LL QILLLLLL   LM LLLLL L TTTTTTTTLAAAAAAAAL   EAA                    NLL    VVVVQQQQQ    LLLLLT     TTTTT                     LLLLLFFFFFIIIII   VVTTTTVVVVLL         IIIIIIIIIIGGGGGGG      Y    LLLLLLLL   TTTTIIIII   TTTKL   LLLLLGGLLLLT IRLL RTT KIS IG      H7BB HH
 EEEEEE   EE        DD   EEEEE     EEQQQEEEEEEDDEE   EE  EEPPPEE  RR   E     EE   DEEEEESSEEE   EEPPPPP  SS        DDE   EEEEEEEEDD       EEDDDD  EEDD     ENNEEEDD   EEEE  PPPPP   EEEE        RREEQQ     DDDDSSQQ   EEE   EEDD            Q   EE   EEEEEKEEE  YYEEEEE    EEEEE EEEEDDEEE   EEEEEEEEEEEEEEEEDEPPP  EE  E   E   EEEEEEEE   EKKKEEEEEQEE EEEEEEEER QQQQEEEEE EEEEEE EEEESSSEEEMMPSSEEEPP EQQQEEAAEEDDEEEEEEEEEAEEA   QQIISSSPEEEEEEEEESSSSS EEERRE EEEEEEEGTTEEEE  EEQQ EEEEEEEEEPP EEEIIEEQQQPPPPEEETSSSEEEPEPEEGESSSSSSEEEIIEPIIGEEEEQDDQQEEQQRRIIE  TSSEEKKHHEAAEQ   QQQQQVV  EEAAEE PE EDRREKKY   ES EEEQE GVVVVVVVVVEDDDDDDDDV   ELL  EEE               LEE    PPPPIIIII    NNNNNK     EEEEE                     VVVVVDDDDDEEEEE   DDLLLLDDDDSS         TTTTTTTEEEDDDDDDD      K        DDDD   LLLLSSSSS   LLLLV   DDDDEDDEEEEL ENQP EQE RKR TE      H8   HH
 AAAAAA   AA        AA   AAAQQ     HHIIIAAAAAAAALL   AAAAQQIIIAA  SS   A     AA   AQQAAAAAQQQ   HHLLLLL  AA        FFA   QQAAAAAAAA       AAQQAA  AAAA     AAAAAAAA   AAAA  LLLLL   AAAA        PPAAAA     AAFFSSAA   AAA   AA              V   PP   AAAAAAQAA  MMAASAA    QQAAA AAAA  RRA   AAAAAAAAAAAAAAAAQQLLL  AA  A   A   AAAAAAAA   ASAAAQQQQAAA AIAQQLLLA AAAACATLL LAAAAL AAAAGGGAAAAAAAAAAASSHAAAAAAAAAL  VVAAAAAAAGALK   AARRNNNLAAAAQAVVFGGGNN AAANNA EEAAAPAKRRIIQA  RNAA VTAAAAACLII VVRRRLRAAAIIIIIISYNNNSSAVGVATANDGGNNNYYARRRVRRAFFAAAKKVVMMAA  TTA  KNNYYYYAAASSAS AASSLSSRRAAAAEERR VA IRNNRHHG   AK ALGSV ITAAAAAAAAANNNNNNNNK   FGG  GGG               AII    VVVVIIIII    IIIIID     AAAAA                     KKKKKPPPPPTTTTT   LLQQQQHTTTRR         VVVVVVVAAAVVVVVVV      T    IIIIKKKK   RRRRLLLLL   QQQYS   VVVVAAAQQQQQ KLAI APH IEQ RI      H3B   H
 QQQQQQ   QQ        QQ   QQQEE     EEKKKQQQQQQQQQQ   QQQQEELLLQQ  QQ   QQQQ  GG   QAAQQQQQAAA   EEQQSSS  DD        QQQ   EEQQQQQQSS       QQKKQQ  QQQQ     QEEQQQQQQQQRRQQ  SSSNN   QQQQ        QQQQQQ     QQQQDDQQ   GGQ   QQPP            Q   SS   QQQQQEEQQQQQQQQNQQ    EEQQQ QQQQEEKKQ   QQQQQQQQQQQQQQQQEESSS  QQ  Q   Q   QQQQQQQQ   QKAAQEEEEQQQSQEQEEEEEE QQQQDQNEE EQQQQE QQQKRRRQQQDDPQQQQQKKQQQQQQQEEQEEE  QQQQQQQTQEQ   QQQQRRRPQQQQQQ  QRRRRR QQQRRQ MMDDQSQLQQQQEQ  QQQQ QYQQQQQEESS   QQQGQQQQKKKK  DQRRRLLQRRKQQQQRRRRRRQQQQQQMQQQQQQQQLLQQQQQQQQQQQ  QRRQQEEEEQDDQCKQQQQQQQEEQQQQAAEE RQ QQRRKRRD   QA QQQQR DKEEEEEEEEQQQQQQQQQP   DEE  GGG               TDD    SSSSNNNNN    TTTTTM     DDDDD                     DDDDDDDDDDNNNNN   QQEEEEKAAAQQ         DDDDDDDAAADDDDDDD      P    EEEEAAAA   EEEELLLLL   EEENQ   NNNNQIIGGGGE Q EP ID  DQE DN      H1    H
 AIIIII   II        II   IIVVV     PPGGGIIIVVVLLPP   IIQQVVVVVHH  LL   AIII  II   IAAIIIIIAAA   SSLLSSS            AAA   VVIIIIIADD       IIHHLL  IILL     AIILLLLLIIIIIII  GGGSS   IIII        LLIILL     LLAAIILL   IIA   IIAA            L   TT   IINNA TIILLLLIAIAI    VVIII AAIIYYKKA   IAIIIIIIAAAAIINNITKKK  AA  A   I   AAANNAII   IIQQATTSSEAALITLTTCVVR EEEEVALVV VIAAAV AAALQQQAAAKK LLIIALLLIEEEAAAAIGYYIIAAAAAAALVVV   AALLQQQGAAIAYAIILQQQQQ AAAKKA KKKKASVNLLDDEA  DLEE VLAAAAAWIEE IINLLPDAAAAAAAIIWVKKKWWAPQQALLLQQQQQQLLLLLAPLLMAAVALGGLLIIAALLLLV  VQQLLKKAAAKKILSAAAAMAALLAAAIGG   QL AKQQTHHS   AG ILIAP AIAAAAAAAAAIIIIIIIIV   EAA  VVV               AVV    SSSSPPPPP    LLLLLL     VVVVV      LL   VVVVV     LLLLLQQQQQPPPPP   TTAAAAYTTTAA         WWWWWWWVVVVVVVVVV      T    VVVVLLLL   AAAANNNNNMMMAAASG   PPPPLVVLLLLA K  V AS   IA TT      H7B  HH
 CAAAAA   AA        AA   AAAVV     GGEEEAAAAAASSGG   AALLVVGGGAA  II   AIII  AA   AAAAAAIIAAA   GGMMTTT            VVA   VVAAAAAADD       AAMMAA  AAAA     AIIAAAAAVVVIIAA  TTTRR   AAAA        VVAAAA     AAVVIIAA   IIA   AAAA            A   DD   AAAAA IAALLLLAAIAA    VVTTA AAAARRVVA  RAASSSSSSMMMAAAAATIAAA  MM  C   A   AAAAAAAA   AISSGDDVVSACSASAIIDTTA SSSSTASTT TAACAT AAALHHHNNCAA LLAAVIICASSSAAAAAVRRPPANNAANNTSTL   DDQQHHHENNAAAAPPLHHHHH SAAHHA MMAAANAMQQYYSA  MISS AAAAAAAETKK PPIQQSTDDDDDDDPPEQYYYSSAQKLALLVKHHHHHAAVQQAQQQM  IAILLLLLLDDQQYYA  VHHAAAAQQAAAVQSGGDDNDDQQGGAALL   RI SAKKSVVP  MGL ANVDF NEIIIIIIIIAVVVVVVVV    NLL  EEE               IAA    AAAASSSSS    IIIIIP     SSSSS      TT   RRRRR     SSSSSVVVVVTTTTT   QQYYYYINNNAA         PPPPPPPNNNSSSSSSS      IV   LLLLAAAA   LLLLIIIIIAAAYYYEV   AAAAIAAIIIIIAS  A KK   LF AR      H2B   H
 TTTTTT   TT        TT   TTSKK     SSTTTTTTTTTTTTT   TTEEKKSSSFF  NN   TKKK  DD   TTTTTTTTTTT   SSDDQQQ            TTT   KKTTTTTTTT       TTRRTT  TTTT     TDDTTTTTKKKDDTT  RRRRR   TTTT        DDTTTT     TTTTDDTT   EES   TTDD            T   AA   TTTTT TTTVVEESTDTT    KKTTT TTTTSSVVT  TTTAAAAAATTTTTTTTTTEEE  TT  T   T   TTTTTTTT   SDEETTTKKVTTDTDSTTTTTV AAAATTTTT TSSTST CTTMIIISSTIIEDDSSTFFDSAAATTAASTSSFFTAATTAALTTD   TTTTIIIATTSTTTFFTIIIII TTTIIS FFIITTTFTTSSTT  CLVV TTTTSTTESTT LLCTTSCSSSPPPPFFTTIIIFFTGISTISLIIIIIITTITTCETTS  TTDIITTAAAASSGGT  DIITTTTTTTIIMRSLLSSTTTRRLLTTFF   AT TGIISIIV  ITF TTSSR TTTTTTTTTTTSSSSSSSS DDDSQQ  RRR               EAA    TTTTSSSSS    RRRRRT     KKKKKIII   NN   RRRRR     SSSSSLLLLLTTTTT   EEEEEEIDDDQQIIIIII   AAAAAAACCCKKKKKKK      GK   NNNNDDDD   LLLLTTTTTLLLEEETT   TTTTVDDSSSSAAS  M LS   ES TT       1    H
 GGGGGG   GG        GG   GGGSS     GGYYYGGGGGGGGGG   GGAASSFFFEE  KK   GKKK  QQ   GSSGGGEEAAA   GGSSSSS            KKG   SSGGGGGGKK       GGKKGG  GGGG     GKKGGGGGKKKQQGG  PPPRR   GGGG        GGGGGG     GGKKQQGG   QQG   GGGG            D   QQ   GGGGG GGGDDRRGGEGG    SSGGG GGGGGGQQG  SGGKKKKKKQQQGGGGGTGAAA  QQ  G   G   GGGGGGKK   GQRRGDDSSGGGQGGGGGASSY GGGGSGKSS SGGGGS GGGKKKKGGGSSKGGGGGDDCGGGGGGIIGSGGSSGGGTTGGSGLG   GGGGKKKPGGGGFGSSGKKKKK GGGKKG XXSSGRGRGGGGTG  KCGG GGGGGGGIS   SSKGGSKGGGSSSSSSSGKKKMMGGAGGSGTAKKKKKGGSGGKRGGG  SGKGGGGGGGGGGGGG  GKKGGGGGGGSSGRKGGGGGGGGGGGGGGG   GS GKAAKGGG  SGG GGGGG GGDDDDDDDDGMMMMMMMM RRRGQQ  GGG               NQQ    GGGGGGGGG    AAAAAG     GGGGGGGG   GG   GGGGG          VVVVVGGGGG   SSSSSSVSSSDDKKKKKK   GGGGGGGDDDGGGGGGGG     GY   KKKKGGGG  GCCCCRRRRRPPPSSSGQGGGGGGGGQQQQQQDGV  SGGG   RK GG       1B    
 GGGGGGGGGGG        GG   GGFMM     GGKKKGGGGGGGGRR   GGGGMMGGGGG  QQ   YGGG  EE   GGGGGGEERRR   GGGGPPP            EEF   MMGGGGGFGG       GGRRGG  GGGG     ATTGGGGGGGGQQGG  QQQQQ   GGGG        PPGGGG     GGEETTGG   EEF   GGAA            E   GG   GGGGG SGGGGCCGGTFG    MMGGG YFGGKKTTF  GGFGGGGGGAAAFGGGGGSPPP  AAGGG   G   FFYGGSGG   GKTTFGGIIGHGKGNGSSLGGG GGGGGYCGG GGFGFG KGGTAAAGGGGGPGGGGFGGGGGGGYHGGGVKKDDFGGTTGGQGGG   GGGGAAAGGGGGFFDDGAAAAA GFHAAGGGGGGGAGGGGNNFN  DGGG GGGGFFFTG   DDDGGGDGGGKKKKDDVGAAAGGFGAGGGGGAAAAAAGGGGGDGGGG  GGKGGNNGGGGGGGGG  GAAGGLLGGFGGGESGGGGGGGGGGGHGGG   GG GDGGSAAG  GFG GGGGF EEGGGGGGGGGKKKKKKKKGYYYRGG  EEE               GTT    NNNNFFFFF    GGGGGR     RRRRRYYY   KK   RRRRR          KKKKKCCCCC   FFGGGGGYYYGGCCCCCC   KKKKKKKVVVRRRRRRRR     GT   EEEEIIII  REEEEYYYYYFFFGGGTRWWWKKKKKRRKKKKGWG RGTYW   FRGNE       4B    
 IIIIIIFFFVV        II   IILII     FFYYYVVVVVVVVFF   IIIIIIFFFLL  TT   LYYY  VV   VLLIIITTVVV   FFIILLL  II        RRL   IIIIIIIVFF       IIFFII  IIII     LTTVVVIIYYYLLII  LLLFF   VVVV        TTIILL     IIRRLLLL   LLI   IIFF            E   FF   IIIIVILIILLEEVILII    IIIII VIIIIIIIM  IVLIIIIIITTTVIILLLLAAA  TTFFI   I   VVIIIMLL   IVYYLIIIIIIIQIIIIIQLLYIIIIILVILL LIIIVL IIIILLLIIIVVIIIIIIVVIIIIIIIYYILIIIIIIIVVIIFILI   IIIILLLFIIIILMIILLLLLL IIILLILFFIIIFLFIILLLI  LLII LLIIIIIIL   IILIIFLIIILLLLVVLILLLLLLRLMILLILLLLLLLLLIILRIIIIILITFFFFLLVVIIIII  ILLLLEELLIVVLLLFFIILIILLFFIIFF   VL FLLLILLV  LLFFVLIIP YLLLLLLLLLIIIIIIIIIIYYYIVVIIYYY               SFF    LLLLVVVVVLLLLSSSSSIIIIIIVVVVVMMMIIIIIVVVIIIIIFFFFF     DDDDDFFFFFIIILLLLLLAMMMRRVVVVVVFFFVVVVVVVFFFVVVVVVVY     AV   FFFFLLLL  FIIIIVVVVVRRRLLLFIIIIIIIIIFFIIIIIIIVIVFMV F FLIIL      E2BB E 
 IIIIIIVVVII        II   IIVII     LLIIIIIIIIIVVLL   VVLLIIIIIRR  LL   TIII  LL   IRRIIIIITTT   LLIIVVV  II        MML   IIIIIIIIFF       IIVVVV  IIII     LLLVVVIIIIILLII  VVVVV   IIII        RRIIVV     VVMMTTVV   LLI   IISS            T   FF   IIIIIIVIIRRRRVIFVI    IIIII IIIITTVVI  LIIYYYYYYVVVIIIMMVVHHH  VVRRI   I   IIIIIIFF   ILTTIVVIILIIMIVVVVCLLKLLLLLLVLLLILIVIIL IVVEFFFIIVLLTFFIIIRRIILLLLIKKIRTTKKIIISSIIAILI   VVIIFFFIIIIITLKKIFFFFF IIIFFVRFFLLIPIFIIGGTI  IILL IIIVVIIVH   KKIIILILLLLLLLRRQIFFFLLVIYVVIIIYFFFFFIIIIIIIMMIRRIVLYYIIHHVVSSIIV  IFFIIIIVVLLLFIVLLIIRIIMMLLIFLL   VI MIYYVYYL  IILYIVVIH V FFFFFFFFVLLLLLLLLRLLLRIIIIIII               YTT    TTTTIIIIISSSSQQQQQVKKKKKFFFFFVVVIIISSRRRTTTTTKKKKK     LLLLLTTTTTVVVIIIIIILLLLIITTTTTTFFFIIIIIIIVVVFFFFFFFVIIIIITV   YYYYLLLL  VVVVVTTTTTTTTIIIYVSSSLLLLSTTIIIIVSRYVIRV  R ILLVI      E2B  EE
 HDDDDDEEEDD        DD   DDDDD     DDDDDDDDDDDDDDD   DDSSDDEEERR  DD   DDDD  DD   DVVDDDEEFFF   DDSSDDD  NN        IID   DDDDDDDDDD       DDDDDD  DDDD     DDDDDDDDDDDDDDD  DDDDD   DDDD        QQDDDD     DDIIEEDD   EED   DDDD            D   DD   DDDDDDDDDDDDDDDNDD    DDDDD DDDDSSDDD  GDDDDDDDDEEEDDDDDDDEEE  EEGGN   D   DDDDDDDD   DQDDDDDDDDDNVDDDDDRDDTEDDDDDDEDDDDDDNDD DDDQLLLDDNDDVHHDDDKKTDDDDDDDDDDSSDDDDDVVDDDDDH   DDDDLLLEDDDDDDDDKLLLLL DDDLLDHXXDDHNHDDDDDDN  DSDD NDDDDDDDDDD DDDDDDDDDDFFFFDDDCQQQWWDTISDSESILLLLLDDSDDDMDDDDDSNDDDDDDDEEQQNND  HLLDDDDLLDDDQDDDDDDHDDTTDDDDDD   CW DDIIDNND  SDDDDDDNK D CCCCCCCCDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDHH    VVVVDDDDDDDDDEEEEEDDDDDDDDDDDDDDDDDAADDDCCCCCDDDDD     SSSSSDDDDDDDDTTCCCCDDDDPPDDDDDDNNNVVVVVVVDDDDDDDDDDHDDDDDEDHHHDDDDHHHHNNNDDDDIIIIISSSCCCDHDDDDDDDSDDHHHHLDDDDDDD  F DDHDD      E3B  E 
 PPPPPPRRRPP        PP   PPPRR     PPEEEPPPPPPPPPPPPPPPTTRRHHHKK  EE   PEEE  CC   PPPPPPKKSSS   PPPPSSS  RR        IIP   RRPPPPPPPP       PPPPPP  PPPP     PNNPPPPPEEEQQPP  SSSGGPPPPPPP        AAPPPP     PPIILLPP   QQP   PPPP            S   PP   PPPPPQRPP  PPPPDPP    RRPPP PPPPPPPPP  PPPPPPPPPPPPPPPPPRR     PPPPP   P   PPPPPPPP   PQLLPRRRRPPPKPRPRRRRRKPPPPPRPPRRPRPPPPR VLLLPPPSSPPPQEEPPPPPKPPPPPLLLPKPPGGPPPPPTTQPKH   GGTTPPPHTTPVIPGGPPPPPP PPPPPLDSSPPIPPSTTLLLP  PPPP PPILPPPPRPP EEPTTPPNNNDDDDGGRSPPPPPPLPLVPCPPPPPPPPPPTTPLSSPEEPVEAAPPPPGGEEEEP  HPPPPPPPPSPPPPPTTII II  AAPLAA   MP LPPPPPPI  PPVPPPPI  P PPPPPPPPIRRRRRRRRDKKKKPPPPPPPPPPPPPPPPPPPPKKPPP    IIIIPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPKKKSSSSSPPPPP     SSSSSPPPPPPPPDD    PEEELLTTTTTTKKKKKKKKKKPPPPPPPPPPIPPPPPSKIIIPPPPPPPPPPLPPPPTTTTTPPP   PPRRRPPPPPLLPPPPPRTSLTPP  P LPPPP       6B    
 TEEVVVFFFNN        HH   VVLRR     NNAAAVVVRRRSSNNTTTVVEERRSSSVV  LL   AAAA  VV   HVVNNNEEGGG   SS  AAA  DD        IIV   RRVVVVVLNN       VVNNRR  VVHH     HLLAAAFFAAAVVVV  SSSAAAAANNNN        FFEEVV     RRIITTII   VVV   NNNN            N   NN   VVEEHDKVV  EEVHLVN    RRVVK IVEELLDDV  ENIIIIIIIFFFLNNEEKKEEE  FFVVG   K   VVIEELVV   KLEEVKKRRTKGGKKIKKIKKLENNNNKTEKKSKEVSIK QILRAAAAATRRGQQQQTVVANNNNIRTTEKLLAAVAAFFAAILKI   AAVVAAASAAVGKCVVDAAAAA FTKAANVQQRRMNMQVVIIKL  NQVV DNNGVKKKKSS MMNAADNTTTGGGGIIKNAAAEEVKEQNATEEAAAAAEEEVVCKVVDVVENLRRSSSSTTQQQQK  AAAEEGGRRVGGDNNSSRRSYYEESSMHNNQQ KE IIEEEEEK  EVGYVNQTE K EEEEEEEESRRRRRRRRRRRRREEAASSSKKKKKKKKKKKKKRRSTT    EEEEHHHHHRRRRVVVVVQTTTTTKKKKKKKKNNNNNRRRRRRRRKKKKKKKKKKKKKKKIIIIIIIIDDTTTTVIIIEETTTTTTNNNDDDDDDDRRRKKKKKKKRSSSSSDKPPPNNNNLLLLIIAVVVVHHHHHDDDTTTSENNNAAAALKKEEEEANSDARVK  D VKLTK       8     
 TEEHHHRRRTT        LL   HHNSS     TTTTTHHHTTTKKTTLLLHHEESSTTTSS  TT   TTTT  LL   LTTTTTTTLLL   TT  TTT  LL        IIS   SSHHHHHGTT       HHTTLL  HHLL     GQQQQQLLTTTLLHH  TTTTTLLLTTTT        QQEEQQ     LLIIQQRR   LLR   TTTT            T   TT   HHFFRLTHH  TTNRSST    SSSSE KKEESSTTK  TTNEEEEEEKKKKTTYYTTKKK  KKTTT   A   HHKFFNDD   EKTTRTTSSTFTLETNTTSSSSTLLLLSFTSSKSHNNNS STSLTTTTTDTTLTTHHTTTTTLLLKTTTHSSSSSSTTKKTTTTSS   TTTTTTTTTTETTSSSTTTTTT NTATTKTTTTTSNHTTTYYTT  TLLL TTTKNGGTSKK SSTTTTCIIIVVVVTTSPTTTSSRCTSNLSLTSSTTTTTLTTTSTTSTTTNTTTSSGGVVTTTTA  STTSSRRTTKNNFTTSSTTTTTEESSTSRRSS SR STTTTTTT  LRTQRTRDS T KKKKKKKKNTTTTTTTTGEEETTTTTSSSSSSSSSSSSSSSSRRSSS    TTTT     TTTTDDDDDRTTTTTSSSSSSSSNNNVVNNNDDDDDTTTTTTTTTTTTTTTDDDDDGGGRRPPPPTPPPIITTTTTTTTTSSSSSSSRRRSSSSSSSTNNNNNVRSSSSSSSTTTTTTTNNNNTTTTTSSSPPPTTSSSRRRRHTTNNNNTSASANHT  T AKSTT       8     
 GSSSSSAAAHHRRR     GG   SSNGGRRRRRLLGGGSSSHHHSSLLRRRSSLLGGRRRAA  QQGGGNGGG  AA   GGGHHHAARRRRRRLL  GGGRRFFRRRRRRR GGN   GGSSSSSNHH  RR   SSQQGGRRSSGG   RRPKKGGGGGNNNAASSRRGGGRRRRRHHHH        NNSSSS     GGGGGGGG   AANRRRHHKKRR          GRRRLLRRRSSQQNYGSS  GGSNANERR  GGSSS GNSSRRGGDRRLHNKKKKKKGGGNKKYYGGSSS  GGAAGRRRS   DDNQQNKK  RSEGGNGGGGGNNRSGSGGKGGTGSSSSGNGGGHGSNGNGRGWRGRRRGGGHHRGGSSGAALESSSNNGGSGRRDDGGGGGGGSGGGR  GGGGTTTQGGSKGHDDHTTTTT GGNTTKACCHHKKSSGGGGGA  AGSS GAKKNNNEGRR NNSGGPAGGGRRRRGGGATTTGGNGCVKRGGCTTTTTKKRGGSGGGGGGKGQGGHHDDSSGGGGS  GTTHH  HHKNNPAAGGGGGGGGGGGNPAAEE GQ CASSGLLR  RNCKSAGGG G AAAAAAAAGGGGGGGGGDNNNSGGRRGGGGGGGGGGGGGGGGMMGGG    PPPPGGGGGGGGGSSSSSGGGGGGKKKKKGGGRRREENNNGGGGGGGGGGDDDDDEEEEERRRRRDDDAAKKKKAQQQGGGGGGGGKKKGGGGGGGNNNQQQQQQQGQQQQQTGSSSGGGGGGGGGGREEEEGGGGGVVVKKKRGGGGGGGGQRRGGGGGGGGNDNG GG GSKGG       7     
 QHHHHHKKKEEKKK     FF   HHQRRQQKKKEEQQQHHHEEEHHEEGGGHHQQRRQQQQQ  GGLLLRQQQ  GG   FEEEEEQQDDDKKKEE  QQQRREEKKKKKKK RRR   RRHHHHHREE  QQ   HHEEFFRRHHFF   EEEGGVVVFFQQQGGHHQQQQQEEGGGEEEE        SSHHII     FFRRTTII   GGAKKKEEEEKK          LKKKEEEEEHHFFEENHH  LLVEGMEKK  RRHHH LEHHRRKKERRREKCCCCCCRRRREEFFHSYYY  RRTTQKKKH   RRLFFTTT  KHGKKQNNRRQEQKHIILLEKKEKVVVVKEKKKRKHVLEKRKDELEEEKKKTTSQQHHQKKEDVVVQQKKHKRRKKQKKKKKKRKKLE  KKEEEEEEQQHELRKKDEEEEE KQVEEDREETTEQHENNQQLE  EKVV QEEDLRRKDKK KKEEEEEDDDKKKKKKKKEEEEELRQQDKQIEEEEEERRKEEEREEKTTESGEEEEGGKKRRKKH  MEESS  KKQFFDEKEEEEKEEEEEEQVKKDD RL QEEEKQQE  KQEKHEKKD EEQQQQQQQQIRRRRRRRRYKKKLAAKKMMMEEEEEEEEEEEEERRKEE    KKKKRRRRRRRRRVVVVVDKKKKKSSSSSKKKRRRRRRRRQQQQQNNNNNLLLLLSSSSSKKKKKRRRKKRRRREDDDEEQQQQQQQQQEEEEEEEEEESSSSSSSVRRRRREKKKKKKKKEEEEEEEQQQQEEEEEKKKRRRKSEEEEEEETKKYYYYEEKAEQQK ER ELEQ        5     
 KRRRRREEENNQQQ     HH   RRRQQKKRRRKKTTTRRRKKKRRRRRRRRRRRQQAAARR  KKRRRRTTT  TT   HLLNNNEETTTRRRRR  RRRKKKKRRRRQQQ RRRRRRQQRRRRRRNN  KK   RRKKHHHHRRHH   AAPTTRRRHHTTTTTRRKKRRRKKRRRNNNN        LLRRRR     HHRRKKRR   TTRQQQNNPPQQ          LQQQQQKKKRRHHLRQRRKKFFFKKRNQQ  QQRRR KMRRRREELRRDNNYYYYYYKKKYNNHHQQQQQ  KKSSKRRRR   RRKHHKNN  DRTTTKQQQQKKKLRQFQQEQETDFFFFQKDQQKQRFRYQKTRRKIIIRRRLLEKKRRKQQQNFFFKKLLRHRRVVTRRTTRRTKQRE  RRRRIIIAGGRRQRVVRVVVII KKRIIKQSSLLRARSRRKKQH  KYFF KKRKYRRKQDD VVKRRRKRRRAAAAPPQRIIIIIKNVERCKCVVVIIIKKCRRKKRRRKKCRRMMRRRRRRAARRR  RIIRR  RRRVVKKRSSRRMRRKKSSKRPPRR KC RKIIELLT  SKSFRQKRM RQ        KKKKKKKKKSRRRHNNKKKKKFFFFFFFFFFFFFEEYRR    VVVVKKKKKQQQQLLLLLVDDDDDAAAAAKKKSSSVVVVVRRRRRIIIIIYYYYYYYYYYKKKKKKKKNNSSSSKCCCKKLLLLLLEEEVVVVVVVNNNAAAAAAAKKKKKKMTYYYIIIIKKKKEEVSSSSQQQQQ   SSSYCKKKEEEETTTLLLLLKDMSKIR KTKSRM K      E2   EE
 LLLLLLMMMLLLLLVVV  LLVVVVVLYYVVVVVLLVVVVVVMMMVVLLVVVLLLLYYLLLLL  RRVVVLVVV  LL   ILLLLLIIVVVVVVLL  VVVVVLLVVVVVVV IILVVVYYLLVVVLLL  VV   VVVVLLLLVVLL   VVLLLVVVLLVVVVVVVVVVVVVVVVVLLLL        LLLLVV     LLVV  VVVVVVVLVVVLLLLVV          LVVVLLVVVVVLLLLYIIVVLLLLVLLVV  YYVVL LLLLIIMMLVVLLYLLLLLLVVVLLLLLYYFFF  MMLLLVVVL   LLLLLLIIIIVITVVYYYYYVMLVLYLHHYYYLMLLLLYMLYYVYILLYYVVYY WWWLLVCCVLLIIYLLLLLLLLLLLIYIILLYLLVVLLSYYLV  LLLLWWWLLLIYFLLLIWWWLL YFMLLLLLLYYYLLLMMLLFM  IFLL AVYLLYYYYVV LLIMMLIVVVVVVVLLYLWWWLLFIIAYFLYLWWWWWIIFLLVILLLLLFYRIIIIIILLLLMMV  LCCLL  VVLYYCIMLLLLLLLLLLLLILLLL VM LVIIMLLY  FYLLLLVLMMMA        YLLLLLLLLLYYYLLLFFFFFIIIIIIIIIIIIILLLFF    YYYYVVVVVIIIILLLLLLIIIIIYYYYYIIIIIILLMMMKKKKKYYYYYVVVVVVVVVVLLLLLIIILLFFFFLSSSLLIIIIIILLLVVVVVVVHHHYYYYYYYIVVVVVLYIIILLLLYYYYVVLMMMMLLLLL   FFFYLFFFSSSSLLLLLLLIFLIFLYI LIMLLLII      E3B  EE
 SPPPPPTTTTTSSSSSS  PPTTTPPSDDSSSSSSSSSSPPPNNNPPTTPPPPPTTDDSSSRR  TTPPPSSSS  SS   PTTTTTAATTTSSSSSDDSSSPPSSSSSSSSS TTYTTTDDPPPPPSTT  PP   PPTTPPTTPPPP   TTSTTDDDPPSSSSSPPSSSSSSSPPPTTTT        SSPPAATTT  PPTTTTAAPPPSSSSSSTTTTSS          PSSSSSTTTPPPPTEDPPPPLLPTTTTTT  DDPPP TTPPTTSSTTTTTTTTTTTTTTTSTTPPDDTTT  TT  SSSSP   SSNPPSSSSSTDSTTTDDDDSSLTPDPDDHSSSSPPPPSSSSSTSDTTTSTTSSTTTTTTSSSNLLDDS   TSSSTTSSDSTTTTCTTTTTTSRSSN  SSTTSSSSTTDSNSTTSSSSSS SSTSSSTTTSSSYPTTTSSNS SSDPP YSTSTSSDSTT TTSTTPSTTTTTTTTTPTSSSSSSSDNSDTDSSSSSSSSDTTSTTTTPPDKTKKGGGGSSLLLLP  SSSSSSSSSTSSSNSTTSSSPPLLTTTNSSTT GD TNHHSPPN  DTSSPNSSTSSD        SSSSSSSSSNSSSTSSAATTTCCCCCCCCCCCCCSSSSS    TTTTSSSSSTTTTTTTTTTGGGGGNNNNNNNNTTTSSTTTSSSSSSSSSSKKKKKNNNNNTTTTTSSS  GGGGNIIINNTTTTTTSSSNNNNNNNDDDNNNNNNNTSSSSSNTKKKNNNNTTTTLLTPPPPSSSSS   GGGKTKKKNNNNTSSSSSSSKNTLSPPSQSAISTTV       2     
 LVVVVVLLLYYAAAVVV  LLPPPVVVIIAAAAALLVVVVVVYYYLLYYAAAVVVVIIAAA    VVVVVVLLL       LAAYYYKKPPPAAALLVVAAAAAQQAAAAAAA AAVAAAIIVVVVVVYY  AA   VVYYLLAAVVLL   PPVVVPPPLLVVVPPVVAAAAAVVLLLYYYY        VVVVPPAAA  LLAAVVPPVVVPPVAAAYYYYAA          LAAAVVPPPVVAAVHIVVAAPPKVVVYLL  IINNV VVVVIIVVVIILYVEEEEEEIIIVYYIIII     LL  LAAAV   VVVTTVVVVVAVVIIVIIVVVVIIVIKIILIILPKKKKIVPIIAIVVLVIAIVVVWWWLLIVVVLLVVV   YKKKVVAAVIIILLVLLIILLIVIVA  LLIIWWWFLLVVIVLLLWWWWW VVVWWV TTVVVYVTMMLLIV LLLQQ YLVVVVVIVAA PPLIIYLLLLAAAALLIVWWWVVVILIVLVLLWWWWWYYLIILVVVVCCMVAVVLLLLLLLLLLLLLVWWMMVVVVVVVLLLMMLLLLLPPMMVVVVLL IL LVLLVLLV  LVTVVLVIVVLV        VLLLLLLLLLLLLFLLLLIIILLLLLLLLLLLLLLLLLL    LLLLLLLLLLLLLFFFFFIIIIIIYYYYYFFFLLLFFLLLVVVVVVVVVVLLLLLLLLLLLLLLLVVVIILLLLLVVVFFLLLLLLTTTVVVVVVVLLLYYYYYYYLLLLLLLLLLLLLLLLLLLLLLLLLLFFFFFVVVLLLLLLLLLLLLLLLLLLLILLAIVIFIILFKRVVV      H5BB HH
 QEEHHHQQQMMNNNSSSAAEEDDDEEADDEESSSAAWWWDDDAAADDHHHHHGGAADDAAA    EETTTRWWWSSAAAAADEELLLMMGGGSSSAAFFWWWQQGGSSSSRRR EENDDDDDDDDDDELL  EE   EEQQEEEEDDEESSSAADHHKKKEEWWWEEDDKKWWWWWHHHLLLL   SS   TTEEEEAAASSEEEEQQEESSSEENRRRLLQQNNAA        SSSSAAAAADDDDDGQEESSLLDDTELDD  DDDDD EDEEEEQQDEEQMTEEEEEEWWWELLDDQQEEE  WW  NSSSDSSSEEGDDDDDVVSDAWWDQQDDSDQEDQDQQ EECYDDDDEDYEEHENEDEEHEHHEKKKGGQKKSHHNND   LEEENKGGNEEESSESSWWAAEADDR  RRDDKKKAAASHNQSSEKKKKK SDEKKH NNKKHSEEDDAADE QEEDD SLHHTEETRQQ SSVDDREAAAQQQQSSKDKKKAADLEFHKEEDKKKKKKKKDDTLDDEAAERQAAEEEERRDDDDSEEDDDEEAAAADKKDIAEEPPEPPDDEEENDDII FE ATDDYTTS  KDEGEHTPPSAE        HPPPPPPPPVTTTKQQDDQQQAAAAAAAAAAAAALLERR    KKKKVVVVVLLLLTTTTTGAAAAADDDDDFFFHHHAAEEEEEEEEQQQQQRRRRRRRRRRVVVVVEEEEELLLLQDDDAASSSSSSKKKAAAAAAAAAADDDDDDDKVVVVVKPTTTKKKKEEEEQQSEEEETTTTTEEELLLSQDDDRRRRLKKNNNNPDAGTESFEAGAEQGTT      H7   HH
 DVVVVVQQQQQDDDEEEEEVVEEEVVDEEKKDDDEEDDDVVVEEEVVQQRRRVVEEDDVVV    EEEEEDDDDEEEEEEEV  QQQDDEEEDDDEERREEERREEDDDDDDD NNEQQQDDVVVVVEQQ  KKEEEKKEEVVDDVVTTEEEEEEKKSSSVVDDDDDVVKKEEEDDQQQQQQQEEEEE   EEVVLLDDDEEVVSSEELLDDDEEEDDDQQEEDDEE        QDDDEEQQQVVIISQDVVKKSSVSEEQEE  DDTTM EEEEEEEEEEEEQEQQQQQQEEEDQQVVDDEEE  EE  EDDDIEEEEEEIIESSDDEVEEEEDDDDEADEVEIDD ATEETTTTATEAAQAVEDEAQTKKEKKKSSEEEDEEIID   ETTTEEQQVDEEQQDSSEESSMEDNQ  SSEEKKKESSVKEQQQEKKKKK EDEKKK EEDDKEVEEEEEEQ EEETT DDKKDEEEDQQ EEDEEEQQQQQQQQEEDEKKKDDNRVCKDEERKKKKKEEDEEDREEEEEEREDDVVEEAAEEEEVEENKKEEQQEEDDDTDEEEEEQEEEEEEEVEEEE RD EEVVEQQE  DEDDAELEEREK        KSSSSSSSSRQQQDEEEEEEEKKKKKKKKKKKKKEEQQQ    EEEERRRRREEEEEEEEEEEEEEEVVVVVDDDEEEEEEEEEEEEEQQQQQEEEEEEEEEEEEEEEDDDVVEEEEESSSEEEEEEEEEEEEEEEEEETTTVVVVVVVDKKKKKDEEEEDDDDEEEEQQQQQQQEEEEEDDDEEEDESSSEEEEEEEEEEEELEEDEEEQDDEQEEGK      H7   HH
 AAAAAAAAALLLLLLLLLLAALLLAAAAALLLLLLLVVVAAALLLAALLLLLAALLAAAAA      LLLAMMMLLAALLLA  LLLSSLLLLLLLLGGLLLLLTTLLLLLLL LLALLLAAAAAAAALL  LLLLLAALLAALLAAAALLLLLA  AAAAAIII  AALLLLLLLLLLLLLLLLLLL   AAAAAALLLLLAALL  AALLL  ALLLLLLLLLLL        SLLLLLLLLAAAAAAAAALLSSAA ALLL  AAAAA AAAALLAAALLVLAAAAAAAIIIALLAAAAHHH  II  ALLLALLLAAAAAAAALLLAVVVASSAALASLASACC AAAAAAAAAAAAALAAAAAALAAA AAAAAAAALAAAAS  LLAAAAAAAAALLAAAAAIIAANAAAL  AAAAVVVAVVAAAAAAVAAAAA ASAAAA VVAAALAVAAAAAA GMAAA ILAAAAALALL AAMAALMAAALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAAMAAAAAAAAGAAAAAAAAAASSAAAAAAEEAAAAAAAGFIVVAAAAAAAVVAAVVAA AA AIAAAPPA  AAVPALAAAAAS        AGGGGGGGGAAAAAGGAAAAAAAAAAAAAAAAAAAAAAA    AAAASSSSSSSSSAAAAAAAAAAAAAAAAAAAAAAGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAEEEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASSSSSAAAAAAAAAFFFFAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAAAAAAAIAAGN      H7BBBHH
 VYYYYYLLLLLFFFFFFLLLLLLLLLVIIAAFFFLLLLLFFFYYYCCLLLLLYYTTIIIII      LLLVLLLLLLLLLLM  LLLVVLLLFFFLLLLIIIQQSSFFFFFFF YYVLLLLLYYYYYVLL  AALLLAAQQYYYYYYYYLLLLLV  CCCYYLLL  YYAAIIILLLLLLLLLLLLLLLLLWWYYCCIIILLYYYY  CCVVV  VFFFLLRRFFVVLLLLLLLLVFFFLLLLLYYLLLTIYYLLAALI YKFF  IIVVY VVYYYYYYVYYALVYYYYYYIIITVVMMIIAAALLIIFFLFFFYLLLVVVMMVIIVVLYSIIVLLIIVCIIYLLLLYLLMYMMMMLCYLLCLYTVCLCVIM IIILLSVVVIIYYVLLTKVVVVCMMYLYYIIVLLIILLILLFI  LLVVIIIVLLYAIVIIVIIIII LVYTTV IIVVILYIVVIILV YVKII LMAAYLLLLLL IIVVVVLEEELLLLAAIVVVVLLVATVAQMKAVVVVVLLEVVVALLMVVIAVEELLLLVVLLVVYLLCIIIIIIEEVAALQMMMSSQSSVVMMCAIIVV VF KIAAYAAF  KVMSYRAVVIIL        AIIIIIIIIVAAAVIIKKKKKLLLLLLLLLLLLLIIDLL    AAAALLLLLMMMMVVVVVVVVVVVLLLLLIIIMMMIIRRRAAAAALLLLLIIIIIIIIIIIIIIIMMMLLIIIIIVVVLLLLLLLLYYYVVVVVVVFFFLLLLLLLLLLLLLIVIIIIIIIIIIIIIVIIIIVVVVVLLLIIIIIVVVIIIIVWWIIIIVVLLATIAVIVLLFM V      H7BB HH
 SKKQQQVVVEERRRNNNEEQQKKKEEKSSEEQQQEECCCQQQSSSAAEEEEEEEQQSSSSSEEEE  RRRRSSSEELLEEEQ  EEERRKKKQQQEEEENNNEEAAQQQQRRR EEKSSSAARRQQQAEE  EEKKKQQDDQQEEQQQQEEEEER  QQQQQSSS  QQEENNNNNEEEQQQQKKKEEDDDRRKKQQSSSEEQQEE  QQSSS  RRRRGGSSRRDDDDDDDDDDAQQQEESSSQQQQAADKKEEQQAA KEKK  TTQQK RRKKNNNNRSSEQNRRRRRRNNNKEEQQDDQQQDDHHEEYQQQREEEAAKQQQQQEEQRQNNKNNSSKSIRKQSEERRQKKKKKKRSKRRDRKKRQRDRDE EEEEEQSSDAAGGIDDGSKKKKAKKKKNNKKLEENNEEAHRKE  EEKKEEEAKKKEEAQQQEEEEE QVLEEEENNTTDRKDSSMMAK  QGEE KQSETRRERDD QQQTTGHEEEDDDDQQKQEEEQQKHQQDSAAQEEEEEEERRRQHRRKRRKDRQQQQQQEETTSSQSSKEEQQGGKKKAASKQQQKKHAAAAQQAKQQAA QK NQQQREEE  SKQARQNEKTEK        DKKKKKKKKSLLLELLEETTTSSSSSSSSSSSSSDDKEE    SSSSEEEEERRRRRRRRRDNNNNNSSSSSQQQRRREEKKKRRRRRNNNNNSSSSSSSSSSDDDDDEEEHHTTTTRPPPGGGGGGGGEEEQQQQQQQHHHSSSSSSSASSSSSGREEEDDDDEEEEEERSSSSRRRRREEETTTLLAAADDDDNKKIIIIEEEEDKEREH SESS K      H4   HH
 QRRRRRLLLRRSSSSSSSSRRAAARRVKKAASSSAASSSRRRRRRRRRRAAARRRRKKVVVAAAA  AAAASSSSSRRGGGR  RRRRRAAASSSAAEESSSVVRRSSSSSSS AAASSSKKRRRRRARR  AAAAAAARRRRAARRRRSSSSSR  QQQRRSSS  RRAASSSRRAAARRRRAAASSTTTRRRRQQTTTSSRRAA  QQAAA  EAAARRRRSSSSTTTTTTTTLSSSAASSSRRRRRQKRRAAPPRR RRSS  RRRRR MKRRAAKKKSS RVRRRRRRSSSERRRRKKKKKSSSSSSQSSSRAAATTMRRKKKSSSRLSSAKKRRSRQSRRRRRNCCRRRRRRSRRCCCCRRQKCCSRR NNNQQMVVAQQRRKCCRRCCCERKKRNAALLHQQSSQQARLHV  RRRRNNNAQQRIQELLSNNNSS RRSNNQVEELLRMWENNHHQC  RHRR ARRQRAAKECC RRRNNRRCCCCCCCLLECKKKQQNELERHKCSDDNNNKKHKKREKKQLLNLRRRKKGGQQAACCRAAHNNKKHHQQTVVTRTEERRRRRQQEERREELL ESAERLLKQQK  HAESRRLKSVQL        RHHHHHHHHKQQQRCCCCVVVKKKKKKKKKKKKKEEVNN    AAAAKKKKKSSSSQQQQQRRRRRRRRRRRRRRKKKLLLLLEEEEEFFFFFRRRRRRRRRREEEEEEEEEEFFFFRSSSKKSSSSSSNNNKKKKKKKVVVRRRRRRRKKKKKKHRSSSSSSSSSSSMMLAAAARRRRRSSSFFFNCNNNAAAAREECCCCRNKKKCRSKS KRKL         3     
 GGGGGGGGGCCQQQEEERRGGGGGCCGSSGGQQQGGQQQGGGCCCGGGGRRRGG  GGGGGGGGG  EEEAQQQCC  RRRG  CCCYYEEEQQQGGGGEEEGGEEQQQQQQQ RRGEEEGGGGGGGGCC  GGEEEGGCCGGHHGGGGRRREEG  GGGGGPPP  GGGGEEEKKEEEAAAAEEEKKGGGQQGGGGGGGRRGGRR  GGEEE  GQQQCCCCQQKKGGGGGGGGDQQQGGEEEGGGGDDGGGKKPPGD GCKK  GGGGG GGAARRGGGRR CNGGGGGGDDDQSSGGGGDDDKKDDKKCQQQGKKKGGGGGGGGKKKG EEGGGGGEGGEGGGGGGRRGGNNNNRGGRRGRGGGGRGGGG GGGKKGGGKGGGGGSSKCSSSGGGGGRRRGGGKKEEKKSGRGK  DDDDGGGGKKGGGGGGGGGGGG EGGGGGKGGGGGCGGNNGGGG NSGNN CCGGNGGRGGG GGSNNCSQQQGGGGGGGDGGGGGGGGGGGGAGGGGGGSSGEESGGGGGGGGFGGGGGGGGGGGGGQQGGGSSGGGGGGGGCCGGGGEGGGGGGGGGGKK GQGGCGGG  G  GGGSGCGGGSGY        GSSSSSSSSGGGGDDDGGKKKEEEEEEEEEEEEENNGGG    GGGGNNNNNFFFFGGGGGGGGGGGGGGGGDDDCCCGGGGGKKKKKGGGGGPPPPPPPPPPNNNNNTTTLLNNNNNGGGGGRRRRRRGGGGGGGGGGGGGGGGGGGGGKKKKKGGGGGQQQQEEEEGGGGGGGGGGGGNNNNNNGDQQQRRRRGDDDDDDGQKSDGGGGG GFRGP        7     
 VLLYYYLLLVVLLLIIIVVFFIIIVVLLLIILLLVVYYYYYYIIIFFIIIIIYY  LLKKKIIIIVVIIIVYYYII  VVVLIIVVVLLIIILLLVVGGYYYVVVVLLLLLLL VVVIIILLYYYYYVVV  IIIIIKKYYYYIIYYYYVVVIILLLLLLFFYYYLLYYIIYYYIIVVVTTTTIIIVVVVVLLLLLLVVVVVYYVVIILLIIILLVLLLVVVVLLIIIIIIIIII LLLVVIIIYYYYLVLYYIILLLLVLIII  LLFFY IVLLIILLLII ILHHHHHHYYYVVVYYLLLLLIIYYIIILLLYVVVVVVYYLIIIIIY YYVVVYYLVIIYILVVSRRLILLLLRIVRRIRYIILRVLLL MMMLLLLLLLLYYLVVTTLLLVVLLYKIIKKILLYYLLNLRFL  VVLLVVVLLLYLTLKKLIIIII LLLIILLLLLLLVYLLLVVTL LILLL LILLLVVLRVV KKILLVILLLVVVVKKKLIIIIIVLILLLVLLMMIIIVVLLLILLLMKKLLLLLIIMMVVLLVVILLLIIVVHHIIILLLVILLLLLLLVVLLVLLLQQ LLVLVIILYYL  LVLSYVLLQLRL        LLLLLLLLLIGGGVIIGGIIILLLLLLLLLLLLLIIL      VVVVIIIIIVVVVFFFFFIIIIIIIIIIIWWWIIIIIIIIMMMMMLLLLLLLLLLLLLLLLLLLLIIILLLLLLILLLLLIIIIIILLLYYYYYYYLLLIIIIIIILIIIIIHLIIILLLLIIIIFFFLLLLLLLLLLLLLLLFILLLQQQQVLLIIIILLIVLIYLLL MFLIV        7B    
 IFFFFFVVVRRIIIIIIIIIIIIIEEVIILLIIILLFFFFFFKKKLLLLIIIFF  IIFFFLLLLTTIIIVFFFII  IIIIIICCCEEIIIIIILLIIFFFLLVVIIIIIII IIVIIIIIFFFFFVEE  LLIIILLVVLLIIFFFFLLLIIVTTLLLFFFFFLLFFLLFFFSSIIIIIIIIIIIIIIIVVFFLLLLLIILLIITTLLIIILLIIIIEELLIIIIIIIIIIIIVIIILLIIIFFIIVGVFFIIVVIINVKVV  IIFFF VVFFIIIIVII QVYYYYYYLLLIKKIIVVAAAIILLIIIIIIFIIIVVVIIVVVIIIF FFVIIIILVIIFIIIILIIVILLLLIVIIIIIFIIVIIIIIVLLLLLILLLVVFFVLLVILLLIVIILIIIVVVVVFFVVVVIIL  VVVVLLLVVVFIVVVVVLLLLL IAVLLLLMMLLIFLMVVVVIILLIIII YIIIFIIILLL VVLVVQILLLLLLLVVIILLLVVVIIIIIIVILLLLLHHVVVLIVVIVVIIEIIIIIILLVVLLLLLILLEELLIIVLLILILLVVIVVIILLVLIIVV VVIITIIILLL  IVLILTVIVVLV        ILLLLLLLLVVVVIVVSSRRRLLLLLLLLLLLLLIII      VVVVLLLLLVVVVIIIIILLLLLLLLLLLIIIIIIIIVVVIIIIILLLLLIIIIIVVVVVVVVVVTTTTTYYYYIIIIIIIIIIIIIIILLLLLLLLLLLLLLLLLILLLLLIFVVVVVVVIIIIVVVVVVVIIIIIIIIYYYIVIIIVVVVLIILLLLIIIILLIIVV IILLIV       8B    
 DDDDDDGGGDDDDDDDDDDNNDDDDDGDDSSDDDDDTTTDDDDDDDDDDDDDDD  DDGGGSSSSEEGGGGTTTSS  DDDTNNDDDGGDDDDDDDDSSSSSSSCCDDDDDDD SSGNNNDDDDNNNGDD  SSNNNVVDDNNTTNNNNSSSGGGQQDDDSSSSSLLDDSSKKKLLDDDDDDDNNNSSDDDTTDDDDDDDSSNNSSEEDDDDDHHGSSSDDSSDDDDSSSSSSSSDDDDDDNNNDDNNDSDDDDDDDDDEGDDD  DDSSN GGDDDDDDGDD DGDDDDDDTTTGDDNNDDNNNDDTTDDDDDDNNNNGGGNNSEETTDD TTGSSDDDDDDNNDNN SSLDDDDDSDDSSSSDGDGSTDDEQDDDDDADDEPPNNDDDDDDDDGDDDDTDDDDDDDTTDDDDTAD  DDAADDDGDDDEDGDDDDDDDD DDDDDDDDDDDDDDDAADDDDGSSDNN DHDDGGGSTDD DDHAAAHEEEDDDDEETTDDDSSGDDEEDDDDDDDDDDDDAAQEAADDDDDGNNTTPPDDSSPPSDDGDDDDDDLLGDDNNHDDGGDSSPPDDDDDDDD DDDDNEEDDDS  DGDDDDEEDDDG        ESSSSSSSSDPPPDDDNNDDDMMMMMMMMMMMMMNND  DDDDDDDDDDDDDNNNNDDDDDDNNNNNVVVVVLLLNNNDDDDDEEEEEVVVVVDDDDDDDDDDDDDDDNNNTTNNNNDKKKDDLLLLLLSSSDDDDDDDDDDTTTTTTTPDDDDDDIDDDEEEENNNNEETDDDDDDDDDDDDNNNNNDDDEEEEDAADDDD DDVDD  DE DDCDDD       7     
 QEEEEEEEEPPRRRKKKRRKKQQQPPRRRKKKKKQQEEEEEERRREEEEQQQEE  QQRRREEMMMMQQQEEEEKKTTRRRRQQPPPTTQQQKKKKKPPEEESSMMKKKKKKK RRPKKKQQEEEEEGPP  QQQQQYYEEKKLLEERRKKKRRPMMQQQKKEEEMMEEQQEEEDDQQQPPPPQQQRREEEMMEEQQKKKRRKKRRMMQQQQQVVPRRRPPPPKKKKEEEEEEEEDKKKKKRRREEKKFLKEEKKAARFMIEMM  KKKKE PPKKLLYYPLLMPMPPPPPPEEEPSSKKRRTTTAAEEKKQKKKEKKKGGSKKPPPKKER EEPKKQQETEAQKRQQPKKEREEEEKTRKKKKEKQVKKNNNKKKKEENTTPSSEEQKKEKQQQPKKKEPLLFFPEEEEEEPEKEL  EESSKKKEEEEHKEFFKKKKRR ESEKKQREEKKSIAEAAPPRSPNEEEE IKDTPPPQQRR FFEAAPNDDDKKKKLLESKKKSSPRNKSEGEIKKEEESSEPPERPPQPPEDADDNNPPEEGGGGKGGEKKEEDDKKPKKREEEEDDPGGGGEERSEEPP RDLIKNNHPPK  EPEEESEKPRPE        SSSSSSSSSPEEEGYYPPKKKEEEEEEEEEEEEEDDPEEEEEEPPPPSSSSSPPPPEEEEEPTTTTTGGGGGEEEPPPAAKKKTTTTTPPPPPRRRRRRRRRRPPPPPTTTPPPPPPIKKKSSTTTTTTLLLSSSSSSSPPPEEEEEEEMDDDDDPLDDDIIIIPPPPLLSEEEEEEEEETTTPPPPPPPPIIIIVKKPPPPSPLGP   KG VLAIPP       3     
 DEEEEEEEENNKKKKKKEEEEDDDEEESSEEKKKEEKKKEEEEEEEEEEEEEEEEESSPPPEEEEDDDDDEEEETTDDEEEDDDEEEGGDDDKKKEEEEGGGEEDDKKKKKKK EEEDDDSSDDEEEEEE  EEDDDSSAADDEEEEEEAAADDEDDEEEEEDDDDDEEEEDDDQQGGGEEEEDDDAASSSDDEEGGTTTAADDEEDDEEAAADDEKKKEEAAEEDDKKKKKKKKHTTTEEDDDEEEEDAKDDKKAADDDEEKK  SSEEEQEEEEEEDDEEEDDEEEEEEEEEEDEEEEKKQQQAAEEAADKKKEDDDEEEEEEDDNNNEEQQEAANNTDDKEQDSSIEENGDDDDEEGEEAEEEDEEAETITDDDNNDQQSHHEEDPPVKDDDEEDDGKEEAAENNDDSSTGEDT  DDRRDDDENNKTVDAAVDDDDD IEEDDGLKKEESDEKKKEETKDEEQEE SETNEDDSRLL GGKKKSENNNLLLLVVYSDDDEEEEHESQNQNDDDDDHHQRRNERRDLLQEDEEHHHHAAHHHHKGGDDDKKVVEEEEEPESDDDDNDDHHDDSNDDVV QAGEQNNQSSK  QEDDEEDDITDE        SEEEEEEEETNNNDNNDDRRRHHHHHHHHHHHHHAADLLEEEEDDDDTTTTTHHHHEEEEEVNNNNNEEEEEKKKTTTSSKKKRRRRRQQQQQNNNNNNNNNNSSSSSQQQVVTTTTQDDD  DDDDDDRRREEEEEEETTTRRRRRRRQTTTTTESEEEDDDDDDDDDDKDDDDNNNNNQQQTTTK NNNDDDDDPPHHHHSNELM L GE   RRAS       1    H
 MMMMMMMMMTTTTTTTTLLTTVVVTTLAANNTTTTTKKKMMMTTTTTAALLLMMDDAAVVVEEEESSVVVLRRRQQSSLLLTTTTTTSSLLLTTTTTIIRRREETTTTTTTTT SSLLLLAAMMMMMLTT  SSLLLDDTTTTTTMMTTQQQVVLSSTTTTTRRRGGMM  WWWIILLLTTTTLLLQQVVVRRMMTTTTTQQTTSSSSTTTTTSSLTTTTTTTTTLLTTTTTTTTTTTTVVLLLMMTTDSFLLTTTTLDSFTTT  AAMMLQFLMMTTTTLTTSTFTTTTTTQQQLTTTTFFIIITTQQMMMTTTLLLLIIFTTYTTIITMSQQLSSSSDDMTMTLTTSEEHQLLLLEDQEETEMFMFETFYSLLLLMMMTTDTTMMYTTATLLLLDTTMTTTAAFMMQQMMVFEVT  MMIILLLLMMMHLMSSTLLLLL SFDLLHTLLTTNSILTTNNLYDSTTII GSQQFVVDDTT SSTIITTMMMTTTTPPDSVVVHHLTTVQVTTTLLLLLTTIIITTIITPPIMFFFFFLLMMAATTMIILLLKKSSTTLTTTTTLLMMTMMTTLLDLLLPP VMTSTTTTVVQM ILLMLSHVPFQP        QTTTTTTTTKAAASSSFFNNNTTTTTTTTTTTTTEEKVVRRRRSSSSGGGGGLLLL     STTTTTVVVVVTTTLLLTTTTTLLLLLTTTTTIIIIIIIIIITTTTTFFFGGNNNNTHHH        GGGTTTTTTTTTTTTTTTTTAGGGGGSSNNNSSSSEEEESSTRRRRTTTTTNNNNNNT IIISSSSLMMSSSSVIRIL V LA   VTTT      H2B   H
 ANNNNNKKKGGLLLLLLYYYYYYYGGSLLLLLLLAAKKKSSSGGGSSVVLLLNNVVLLSSSLLLLVVYYYSQQQYYVVFFFYYYGGGIIYYYLLLAAVVRRRLLVVLLLLLLL YYHFFFLLNNNNNRGG  LLFFFSSKKHHYYNNYYYYYYYYVVWWWCCKKKVVNN  RRRRRLLLGGGGFFFFFFFFVVNNWWLLLFFHHYYSSLLLLLVVHLLLGGGGLLFFFFFFFFFFILLLVVFFFNNNNRVLNNFFRRYRVKGVV  LLLLSKKHNNYYYYHYYVGKGGGGGGRRRLGGLLFFEEEFFRRYYALLLNFFFRRKNNQGGYYFNVRRHLLLLLRGANLYLLEYYGYCCCCYRYYYLYNKAKLLDMMSAAAFFVAAMAANNKFFVGVVVHEAAILYYAARVVKKVVRAYAA  VVAAAAARVVNMVQTTAAAAAA AKKAAMVLLAATRFLAACCVQHLGQFF GGLKKFFLVFF MMGAAGGIIIFFFFMMLAAAARRHMAALLAVVVVAAAGGLAARMAAAAAAVGLLHHHHAAAAAAFFFAAAVVAAAAHAAFGGMMVVAVVAAMMQAMMAA TFVGGAAYVVAV LHL ARKAASVI        LAAAAAAAAASSSLAAVVGGGVVVVVVVVVVVVVGGAVVFFFFAAAAHHHHHPPPP     GCCCCCVVVVVPPPSSSIIYYYAAAAAVVVVVAAAAAAAAAA     YYYIIGGGGGHHH        AAAVVVVVVV   AAAAAAAAHHHHHV NNNVVVVAAAA  ILLLLRRRRRSSSGGGTLVVVVVVVVKKVVVVAVSFF KKAHG  PGGG      H9B  HH
 TEERRRAAALLDDDDDDQQDDEEELLEDDDDDDDQQKKKRRRLLLRRQQDDDSSRRDDLLLQQQQRREEEERRREEHHCCCDEELLLAAEEEDDDHHQQRRRQQRRDDDDDDD RREKKKDDRRRRRELL  DDEEEEERRDDNNRREEEEEEESKKQQQDDCCCCCRR  RRRVVDDDLLLLEEEEEEEETTEEQQEEEDDDDHHTTSSDDDHHNDDDLLLLDDNNAAAAAAAAMDDDQQEEERREEEQERREERRRQRELQQ  DDKKEKDDEENNMMDNNQLTLLLLLLEEEELLEEDEIIIDDLLDDGDDDENNNEEDEEELLDDKEKMMEDDDDQDKKGERDDFHHILRRRRHDLHHEHKSVDHEDQQKNNNRRTSSNVVKKSKKDLHHHNSLLKQNNLLSRRKKRRKQQRG  RRLLNNNERREQQELLTDDDNN KSETTYEQQTTQCHHLLKKNDFKLLEE VLQYGAADSDD LLMLLLLKKKDDDDLLQLKKKQQEFSVQSHLSNNNNNLLGLLMFLLCLLTQAKKEEEEKKVVIIGHHKNNHHNNRREMMQLLWWTTEKKVVWWDRWWLL VREQMTTLLLID CESEALEKLPFA        Q        VDDDL  FFRRRTTTTTTTTTTTTTTTKKKKKKKLLLLYYYYYCCCC     DEEEEERRRRRIIICCCQQQQQDDDDDPPPPPYYYYYYYYYY     EEEKKCCCCEHHH        LLLEEEEEEE   EEEEEEEQYYYYYLSIIILLLL      FCCCCTTTTTTTTCCCLSEEELLLLKQQCCCCQETTEQEENHQ  VRKQ      H9   HH
 RIIVVVAAAYYEEEQQQQQMMQQQRRQQQKKEEEGGEEEVVVAAAAAGGRRRVVRRQQWWWRRRRQQQQQKAAAQQRRQQQMQQYYYGGRRREEEGGHHQQQRRKKEEEEEEE EEKKKKQQVVIIIKRR  KKQQQVVAARRLLIIRRQQQQQRRRSSSRRAAARRVV  QQQMMRRRLLLLQQQQQEEEQQIINNVVVQQQQEERRKKKKKRRKEEERRAAEEHHEEEEEEEEAEEEGGKKKIIKKQRQIIEEAASQQKCQQ  QQSSIAKRIILLEEKLLRSKLLLLLLSSSHCCRRQQPPPKKEEQQKEEEIKKKKKKKKKLLEEDIQEEKQQKKKARKIKAKKALARQAAAAAVQLLMLIKRKRQVRRFNNNIIKRRHKKIIRDDIVAAAKKRRIRLLKKRIIDDIIRQLQQ  IIVVNNNRTTIRKRKKVNNNNN QRQHHKQKKRRSFLKVVTTKAPQRQKK FRRKNKKRRQQ KKRVVGRIIIQQQQRRQLNNNQQKRIRRHSQVNNNNNLLQVVWRLLGRRQKARRKKKKVVKKKKKEEENNKKMMRRKRRSRRGGEEKEEKKGGKKTTRR RQIRKVVEFFMR QKSSALEVRR G        R        FAAAH  LLVVVTTTTTTTTTTTTTVVTQQPPPPVVVVCCCCCYYYY     VYYYYYRRRRRSSSWWWVVVVVRRRRREEEEEMMMMMMMMMM     MMMNNLLLLYQQQKK      KKKKKKKKKK   VVVVVVVANNNNNLPYYYVVVV      NQQQQYYYYY   LLLHRVVVIIIISAATTTTRVFKLKKRKKKA PIPI      H9   HH
 LLLLLLPPPLLLLLLLLLLLLLLLLLLYYLLLLLLLLLLLLLLLLLLLLVVVLLYYYYEEELLLLSSLLLLLLLLLFFLLLLLLLLLVVLLLLLLLLFFLLLLLYYLLLLLLL VVLLLLYYLLLLLLLL  LLLLLRRLLLLLLLLLLLLLLLLYYLLLLLLLLYYLL  LLLLLVVVFFFFLLLLLLLLLLLLLLLLLLLLLVVEELLLLLCCMLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLIYYLLLLFFLIYLLLL  YYFFLLLLLLLLLLLLLYMLLLLLLLKKKLLLIIYYLLLLLLLLLLLLLLLLLLLLLLLLLLLLLYLLLYYYYLLLYLYLYYLYLLLLLLLLLLYYLYLLLLLLVLLLLLLIILIILLLLLLLLQLLLLMLVVLPLLVVLIILLIIFLYLL  IIIILLLLIILLYLVVLLLLLL ILLLLLLVVIILLIVIIIIYLILLLLL LLLLLLLYYLLLVVLIILLIIILLLLVVYVLLLIILLLLLLILLLLLLLLLLVVLLVVILLLLTIILLMMIILLLLLQQLLLLLLLLLLIILFLVV  V  LLVVLLVVLL LLFYFLLLLLLI LLVLLLLIVL L        L        FIIID  VVIIIQQQQQQQQQQQQQLLLLLFFFFKKKKYYYYYFFFFRRRRRL     QQQQQIIIDDDSSFFFLLLLLIIIIIVVVVVVVVVV     EEEDDVVVVISSSQQ      VVVLLLLLLL   VVVVVVVVSSSSSKLVVVRRRR      VPPPPRRRRR   VVVKVVVVRRRRVLLLLLLIVFLLNSPLPLQ V DL      H4B   H
 KTTAAATTTLLSSSQQQQQRRKKKLLGRR  NNNRREEEEEELLLSSRRLLLLLLLRRLLLVVAALLEEELIIIKKLLQQQREELLLLLEEENNNQQLLLLLAALLNNNNTTT LLLKKKRRAAAAALLL  VVEEEDDEELLRRAASSRRREERLLEEESSVVVLLAA  LLLEELLLLLLLEEEKK   LLTTLLCCCKKSSLLLLEEHHHLLLSSSLLLLNNHH        KRRRQQTTTEETTYLRLLQQQQNYLLLDD  RRSSSTLLTTKKSSLKKLLLFFFFFFKKKLLLTTRRQQQQQKKQQKNNNSHHHLLITTRLLIISTLIILRRRRSIKLLRNRRLKLLQKKKKLLQKRLKTMKLLLSLLTKKKAAKLLRMMTTLEELLQQQLFLLSAKKLLLAALLAANRRKH  AALLKKKLAASLQLLLKKKKKK QLLKKLHLLLLLLNLLLSSKESQLQNN FLLLQLLRKVVKLLLLLLLVVVIIIILLKLKKKRRLLKLLQLQNKKKKKLLKLLLLLLLLLQSGLLKKAAAAMMMMT  KKKLLFFHHLLLEFLLL  N  MMLLLDLLLL LQ LLSSSKKLS KLLEAPLVLK I        L        NHHHL  DDSSSSSSSSSSSSSSSS  ESSDDDDDDDDPPPPPDDDDQQQQQV     DDDDDEEEKKKNNRRRLLLLLTTTTT     NNNNNTTTTTGGGRRDDDDNSSSNNNNNNNNFFFAAAAAAATTTKKKKKKKTGGGGGDLLLLDDDD    TTSSSSSDDDDD   DDDSP   DDDDLIIQQQQDDDETSLALEVN L NL      H2    H
 PDDDDDSSSPPQQQDDDRRSSRRRPPQAA  QQQEEEEEDDDPPPAAEEEEEDDQQSSLLLQQQQEERRRLQQQEECCRRRSRRPPPVV   QQQEERRHHHEEEEQQQQQQQ EESEEESSDDDDDSPP  QQRRRVVAAPPEEDDEEEEERRREEEEEEEQQQCCDDNNRRREEVVVSSSSRRREE   EEDDSSRRRDDEEEEEEPPHHHRRSQQQPPPPQQQQ        AQQQEEQQQDDDDTQADDQQNNNTKSPDD  AAEEDGSSDDQQDDSQQQESPPPPPPQQQLRREESSRRRKKKKQQYQQQDNNNSSSEELPPKKAYARRSSSAAQTPESANAAVEVEEEEEEVKEDDKDDSPSVTRNNKSSSSSPEEEGGDDEKKSPCCCLAQQDLQQEEESSRRSSSQDKS  SSEESSSDSSYNEDEESSSSSS QETSSNSAAEEHPPMEEDDERGEPEPP PPNNASSSEKKQEEPEELPTTTKKKKEEKESSSAASGSENETESSSSSSDDEEEPGEETQQENFLLSSSSTTDDGGD  KSSNNKKQQLEEEPPKK  L  AAKKAKKKQQ ED EPNNESSEL ESQVDVATQL          NNNNNNNNNRTTTEVVQQNNNSSSSSSSSSSSSS  RDDPPPPLLLLQQQQQEEEELLLLLP     SSSSSEEERRRAANNNPPPPPNNNNN     PPPPPVVVVVNNNGGPPPPERRRVVKKKKKKGGGEEEEEEEAAADDDDDDDESSSSSGLPPPEEEEVVVVLLSNNNNPPPPP   PPPEG   EEEEDPPEEEEGTTVTQIMPVQQ S TG      H1    H
 APPPPPCCCLLGGGGGGGGYYGGGLLAGG  GGGGGIIIPPPIIIYYGGGGGPPGGGGFFFGGGGGGGGGAEEEGGGGGGGFGGLLLPP   GGGGGGGRRRGGGGGGGGGGG AAAGGGGGPPPPPAAA  GGGGGFFEELLGGPPRRGGGGGAGGCCCRREEEGGPPWWLLLEEGGGLLLLGGGGGAAARRPPGGGGGGGRRAAGGGGGGGGGAGGGLLLLGGGGAAAAAAAAMGGGGGGGGPPFFAGGPPGGLLFAGALGG  GGQQPFAAPPGGQQAGGGVAIIIIIIDDDALLYYGG   GGEEGGAGGGPGGGAAATTAVVGGGEGKKAGGGGGAAGPGPGGAGAALCCCCAALGGGGEAAAAGAAAAIIIHHAGGGKKEEAGGLIYYYAAAAQKGGAAARRQQRRICGVG  NNSSIIIAHHEAGAAALVVVII CAAVVAGCCRRAFASSSIILAVSVLLL FVAAAAAQGGGLAAISSLVNNNGGGGGGGAMMMLLAAIAALYLVVVIIIAALSSVASSHAAIALSSCCCCNNRRFFS  IVVWWGGIIAGGLVVSS  C  QQSSARSSSS AL VVVVQIIAA LASAPQLNSAL VVVVVVVVAIIIIIIIINTTT LLEEIIIAAAAAAAAAAAAA  LFFKKKKAAAA     QQQQFFFFFL     VVVVV   AAA  IIICCCCCRRRRR          VVVVVLLLAAFFFFSSSSFFFFFFFFLLLAAAAAAALLLSSSSSSSA     AM   QQQQVVVVVVFYYYYAAAAAFFFFFFML   QQQQLAALLLLFKAKSYGPCVVF TALV       0B   H
 QSSSSSCCCTTKKK   EEVVQQQKKETT  KKKRREEESSSVVVCCRR   DDHHTTSSSRRHHGGQQQEYYYKKSSEEELQQSSSSS   KKKRRTTYYYHHTTKKKKKKK EEEEEETTSSSSSEEE  MMQQQEEQQSSTTSSKKKKKQQETTEEEKKYYYVVSSEEQQQMMEEESSSSQQQKKQQQEESSKKHHHKKRREEIITTTTTSSETTTSSKKRRKKQQQQQQQQMKKKTTDDDSSVVETSTTKKLLVETEKEE  TTTTTDEESSKKEEEKKTKEYYYYYYQQQENNTTSS   EEQQKKQKKKSKKKEEEVVECCNN GEEEESSNNKEQTDTSTTGRGQEYYYYGEERHKHSEYEGRNQQTCCCQQQQQKLLSSEKKKHIIIEEQQNQKKQQEQQYYQQSEKEK  QQLLCCCQQQGQLQQQTCCCCC EEECCQQDDQQQENDLLKKNEVQRNKK EKQQEEESKEEQQQRLLKKQQQEEEEQQKQQQQYYEQTEQNQNTCCCCCTTNLLQQLLQQQSEVEEEELLQQMMFFS  ECCMMQQQQEQQSKKDD  E  TTDDEEDDQQ QN KNQQEPPQQ NEENAQEQQER KKKKKKKKQKKKKKKKKTYYY HHSSQQQQQQQQQQQQQQQQ  Q  YYYYKKKK         KKKKKA     EEEEE   EEE  QQQGGGGGKKKKK          KKKKKNNN  QQQQKTTTTTRRRRRRLLL       KKKVVVVVVVR     KE   KKKKKKKKKKQEEEE     KKKQQQNT   RRRRRGGNNNNKNCQLKNKVTST ESGT       3    H
 KDDDDDGGGSSKKK   RRDDTTTGGRLL  KKKLLKKKDDDKKKDDLL   DDSSLLEEETTSSNNTTTRKKKKKGGRRRDTTSSSKK   KKKLLRRRRRTTGGKKKKRRR SSRTTTLLDDDDDRKK  VVTTTKKVVDDRRDDLLKKK  GGGDDDLLKKKGGDDNNGGGKK   KKKKTTTKKGGGMMDDRRRRRKKDDSSNNDDLLLGGRTTTSSIIKKKKGGGGGGGGVKKKLLTTTDDDDKGLDDKKLLDKNREKK  LLGGDDRRDDRRCCRKKSDRIIIIIISSSQKKDDLL   KKSSKKKKKKD   RRRKKRIILL DKNNRLLLLLAKSDMKMMELEIDVVVVEADLLKLDRKKEKRKKSIIIDDKDDINNDDKKKGDDDDRAEEDDRRDDKDDRRDDDLINK  DDWWIIIKDDDKIKDDCIIIII LKAIIKKKKVVKKHKWWDDSKDHTNLL RSKKKRRIDKKEDDPWWIPNNNKKKKDDIRLLLIIKNLDKSVS IIDDDKKEWWEHGGVEENSDKKEEDDDDSSDDD  KIISSKKAAKDDTQQKK  L  DDKKDDKKDD DD DSLLCDDNK KRKNDQKNNQDMDDDDDDDDKDDDDDDDDKKKK PPGGNNNSSSSSSSSSSSSSNNK  EEEEAAAA         DDDDDKKKKKKLLLLL   RRR  NNNYYYYYKKKKKDDDDD     DDDDDKKK  DDDDGSSSDDDDDDDDNNN       DDDDDDDDDDR     KS   DDDDDDDDDDDSSSS     DDDDDDEKDDDEEEE DDDDDDDDK GDTSVKRD DSQD       1     
 ADDDDDVVVAATTT   SSPPTTTAAASS  TTTAAQQQDDDNNNPPAA   DDSSSSAAATTTTFFTTTAAAASSAASSSPTTTTTVV   TTTAASSVVVTTSSTTTTTTT AAASSSSSDDDDDAAA  TTSSSAAEEAATTDDSSSSS  ACCPPPTTAAAAADDLLQQQRR       SSSSSTTTAADDTTAAASSDDAAAAAAPPPAAATTTSSTTTTSSRRRRRRRRPTTTAALLLDDPPACSDD  PPPASAKTT  SSDDDPAADDDDEEATTCGATTTTTTSSSA  PPSS     SSKKATTTD   AAAGGATTTT DSSSATTSSTAACDT TTTPTARDDDDTARPPTPDAAATTAAAVPPPVVALLTMMDDATTTKPPPAASSPTDDPPAIITTIITVPPA  TTSSPPPAIIDATATTPPPPPP VAAPPATAAAAAATASSEEPATLLAVV HLAAAAATTNNAMMPSSTLTTTTTTTIIPGAAAPPSCPPAAQA PPVVVPPASSAPSSPGGAAPVVAASSAAMMAAD  PPPSSQQAA LLAKLTT  Q  AATTPPTTII PA GIHHEVVPA AATVDPSPIALSTTTTTTTTATTTTTTTT III DDNNAAAKKKKKKKKKKKKKTT VVAAAAKKKK         PPPPP IIIIIIIIII        AAADDDDDTTTTTPPPPP     LLLLL     IIII AAAPPNNNNNN          GGGVVVVVVVD     KA   KKKKFFFFTTPKKKK     PPPIIIYKAAASSSS IIGGGGL   ILATGASS PAVP       4    H
 FTTTTTVVVRRVVV   VVSS   EEAIIVVVVVVVSSSTTTKKKSSAA   TTIIIIVVVVVVVII   VVVVVVVVVVVS     EE   VVVVVVVTTTVVIIVVVVVVV WWV   IITTTTTVEE  VV   FFVVRRLLTTFFVVV  VIINNNFFVVVVVTTVVVVVWWVVV       VVRRRLLTTLL   VVSSWWIITTIIIVVVVVVRRFFVVVVTTTTTTTTFVVVVVVVVTTVVIIL    FFVVIVKQQKKIIIITFVATTIIWWVIII VFFFFFFFFFV  TTLLFFF  FFPPFVVVTAAAVVVFFVFF   TIFFVLLIISCFITL LLKVKTKPPPPKSKIIVITVFVKVVFFSDDDFFYKKSFFTTIIIIKDDDVAVVNMIIAAVFFVVFFEIIQI  NNFFDDDAFFTFLVAARDDDDD FVCDDFIVVKKFKKIFFVVIVTVKKFF LKFFVVVLTVVKAAKFFFKVVVVVVVAAIYVVVEEVNDKFVTK DDVVV  KFFKHFFNSSSYKVVLLCCPPFFEET  EDDTTEETT KKICKLL  L  RRLLHVLLNN RK IKDDWLLKY KVLTTSCVTIVDVVVVVVVVFVVVVVVVV QQQ DDVVVVVTTTTTTTTTTTTTEEVVVIIIILLLL         KKKKK DDDDDSSSSS        VVVEEEEEKKKKKKKKKKKKKKKDDDDDKKK  IIII TTTDDLLLLLLVVV       VVVSSSSSSSA     FS   VVVVKKKKEEAIIII     KKKIII SKKKVVVV IIIIIIR   RVSIDVKDVKDFK       1     
 IKKKKKQQQTTQQQ   RRTT   KKATTKK   AAQQQ   KKKTTVV   KKAATTVVV    TT   TTTTKKGGQQQT     PP      LLAALLL  SS    QQQ SST   TTKKKKKTSS       QQTTKK  KKRR     TVVTTTRRSSSSSKKHHTTTAARRR         TTTQQKKSS   KKTTSSAALLHHHSST   PPLL  KKTTTTTTTTK   SS   KKTTTAT  RRRRTTATKDDTTTTKKKSTTKKRREETNNA TKKKKKKQQQT  TTTTAAATTKK  V   KTTTTTTIITKK   KATTTNNTTRTVSKT TTPSPGSEEEEPTSSSTSKTVTPTVTTTVVVNNFRRQQQKKLPPAKTTTII  TTRRTTLSSTTNNTTSTATTSSMMVVVKNNKTTTTTTVVVVVTTLIVVTDSSRRTTRSMMSSATTDCKDD TSTTTTTNTSSTTTCMMRCTTTHHHHTTSSSSSTTTSKSSSGKLVVPPP  QTTCSTTSVVSTAYYTTKKSSSSSSKTTIVVQQNNGG RRCSSAA  S  SSAATTAATT SK SSTTESSSS STHSKSRSDLSTSSSSSSSSTSSSSSSSS KKKSSSTTTTTVVVVVVVVVVVVVTTMTTIIII         TTTTTTTTT DDDDDKKKKK        NNNEEEEESSSSSTTTTTTTTTTGGGGGTTT  KKKK AAATTTTTTTTPPP       TTTKKKKKKKE      ANNN    TTTTHHSPPPPTTTTTSSSKKK TNNN    TTTVVVVS  TNSVDNHPSAKSST       2     
 GGGGGGGGGLLEEE   GGDD   GGGEEGG   GGVVV   DDDGGGG   GGGGEEEEE    NN   GGGGDDGG   E     GG      GGGGGGG  GG    EEE RRG   EEGGGGGGGG       GGGGLL  GGGG     GGGLLLGGGGGGGGGGGAAAPPPPP         AAAGGGGGG   DDGGRRGGGGNNNGGG   QQGG  DDAAAAAAAAG   DD   GGDDGGQ  PPGGKGGGQEEGGEEGGGGGGGGNNEEGSSG GGGGGGGGGGG  DDQQGGGPPGG  G   GLLLGGGGGGGG   GGGGGQQEEDGGGGE QQCECGGTTTTCGGEEGEGGGGCGGGGKMMMDDGGGEGGGGGEEG EEEGG  ENNNGGGNNEEDDLGEKEGGGGGGMMMGDDGGGGGGKMMMMMGGGGMMGEGGGGGGCGGGNNGGHEGIGG GGGGG  EEEEPGGGGGTGGGGEEEEGGEGSSSTTGGMGGPGLPMMNNN  IGGGGGGGSSCGNGGGGTTGGGGCCGGGKMMTTGGGGGGGGGGGG  G  GGGGGGGGKK GC DGMMETTGG PDGGGGGGGGGGNNNNNNNNGGGGGGGGG RRRGSS  GGGIIIIIIIIIIIIIGGDQQGGGG         EEEEGGGGG GGGGGPPPPPPPP   GGNNNGGGGGTTTTTGGGGGGGGGGGGGGGGGG  RRRRGTTTGGGGGGGGPPP       GGGPPPPPPPG      AGGG    NNNNDDGPPPPGGGGGGGGRRR  DDD    SKKNNNNN  GGGPGGGPGGSKVG       4     
 FFFFFF   LL      QQEE   SSYFFVV   LLIII   YYYEEHH   FFEEFFQQQ    EE   YPPP  VV   E     EE      LLVVQQQ  EE    VVVEQQY   FFFFFFFYSSEE     RRQQTT  FFLL     EEEEEELLEEEQQFF  YYYIIEEE         GGG  FF     IIQQQQEEGG   VVY   LLGG    RRRRRRRRQ   VV   FFEEFEF  EERRKFEYVVVEEYYFFFKYYFFIIIIYTTE YLLLLLLTTTF  EEFFKKKQQLL  F   FKKKYYYDDYLL   FELLYFFFFIFFKFF FFPFPIKEEEEPFKFFIFFKFYPIYVIEPPPQQFKKIFFFFYVVM HHHYY  ESIIKKYQQEEQQEIFE KKEEEEPPPYQQFEEHKKRPPPPPLIYFPPEVVVKKVAFIEEKKFYSKRIVV TRVVY  FSVVEKKREELREEEVVVVKKFEEEEEEYQPCEAIIDPPMMM  IEERHEEQQQTIRTTPPLLKKFFEEFQQEPPNNKKIIEKKHGKVV  R  EEVVKEVVEEFHV KRPPIKKEFETKQDFKKQKYAERRRRRRRREKKKKKKKKHSSSQKK  EEEHHHHHHHHHHHHHKKTKKEEEE         QQQQNNNNN RRRRRRRRRRLLL   RREEERRRRRIIIIIKKKKKKKKKKTTTTTEEEYYKKKKIAAARREEEEEEAAA       QQQRRRRRRRYDDDDD SNNN    QQQQKKEIIIINNNNNEEEKKK  RRR    EQQKKKKDIKEPSYQPVTRELSVK       1B    
 KNNQQQSSSAA   SSSKKKK   TTSAA     KKKKK   KKKPPKK   NNKKNNRRR    KK   TQQQ  RREEER     KK      KKVVVVV  KK    TTTKTTT   AANNFFFTTTKK     TTRRQQ  NNRR     RKKQQQRR   RRFFRRQQQKKEEE         EEERRNNSS   SSQQTTKKAA   LLK   VVMM    EEEEEEEET   SS   FFKKKRS  EERRKTTKQGGKKTTTTNTKKNNKKTTKKKKKKRRRRRRRRRT  KKAKNNNDDRR  R   HDDDTTRKKTRR  KNIRRKEEAAEKKTNT RRSASRQQQQQSKQAAK NTQKSKRRRKHHHRRKKKTSSNNKKKK SSSKK  NKKKRRTRRKKRRKMAA NNRRIIHHHTRRNRRKRRRHHHHHKIAQHHRQLLKKRENLIIEERERMKSRRKEKERK  SRKKDRRKIISKRRRKKKKRRAISSSIIKRNRRTRSKHHQQQ  SIISRIIRRRTERVVEEIIRRFFAANKKTHHQQPPRRRKKEKKVV  K  SSVVSNVVRRKRQ VKNNTIIKEKTKIKFISKRSIKWWWWWWWWRWWWWWWWWEEEETQQ  KKKTTTTTTTTTTTTTFFSPPTTTT    KKKKKMMMMIIIIISKKKKKEEEEEQQQMMMTTKKKPPPPPTTTTTKKKKKKKKKKIIIIIVVVEEKKKKREEEQQIIIIIILLL       LLLEEEEEEERKKKKK QQQQ    YYYYIISGGGGVVVVVIIIKKK  KKK    YRRVVVVYKTTKVSQQKAQSRSG        0   E 
 MLLIIIVVVDD   LLLLLLL   MMLDDVV   KKVVV   HHHVVKKVVVLLLLMMVVV    MM   IVVVLLLLVVVL     MM      KKLLAAA  II       MLLI   DDLLDDDLMMVV     VVRRII  LLII     VMMLLLIIVVVLLDDVVLLLVVLLL         VVVVVLLVV   EEIILLMMAALLLLLI   DDVV  VVVVVVVVVVV   MM   DDLLVLP  VVVVVVLITSSFFAANNLVIILLLLTTILLMSIRRRRRRVVVD  QQDTMMMVVDD  M   LVVVIIIRRIII  LLLVVVLLDDLLLILQ SSLLLLYDDDDLLYLLM LIMILMLLLIIIIVVLVVLLLLLLMMM VVVIL  LLLLLLLVVEEVVIMLL LLVVLLMMMVVVLLIVLLIMMMMMKILLMMLKDDVVLLLDLLLLILMDILKKIMVLLI  TMMMIVVILLPIVVVMMMMLLLFPPPLLIMLLLVLLMMMLLL  IIIVMIILLLLLLHHAADDLLDDLLLLLLMMNNEEVVQVVLVVDD  V  LLDDLLDDLLLLL LIIIIEELMMILRLDVLVLIMILLLLLLLLLMMMMMMMMMLLLLLL  LLLSSSSSSSSSSSSSVVIIIVVVVVVVVIIIIIYYYYYYYYYLIIIIIMMMMMLLLLLLIILLLVVVVVIIIIIIIIIIIIIIIEEEEELLLLLYYYYILLLMMCCCCCCMMM       VVVMMMMMMMFIIIIILVIIIVVVVKKKKVVLMMMMYYYYYYYYYYY LIIIVVVVILLLLLLVIITMILAMVTMLLLL        2B  E 
 STTTTTPPPEE   SSSSSSS   SSSPPSS   SSPPP      TTSSVVVTTTTSSAAA    SS   SSSSSSSSAAAS     SS      SSSSKKK  SS       STTS   MMTTPPPSSSTT     SSSSTT  TTSS     SSSPPPSSTTTSSPPSSLLLSSLLL         AAATTTTSS   TTTTTTGGSSHHHGGS   SSSS  SSSSSSSSSSS   RR   PPSSPST  EESSSSSSSSSTTSSPPTSSSTTSSTTSSSSPSGGGGGGPPPP  SSMSTTTSSHH  S   TSSSSSSVVSSS  TTSSSSSSMMPSSSTPPSSS SPSSSSSSSS LPATSSSSPSSSSQQQTTSSSPTTTTSSSP SSSSS  TSSSTTSTTKKTTTSSS LLTTPPQQQPTTTSSPTTTQQQQQSSSSRRASSSSSSTTSPPTTPSSESPPPSSSSAS  SSSSKTTNPPSTAAASSSSSSMPLLLSSSTGTSPTPPQQSSS  PPPSTPPTSSPSSSSTTPPTTSSTTTLLPQQKKIIPPKSSPGSGG  G  SSGGSNGGTTTTPPTSDDSSSRSSPPSTPGPSSPSSSSSSSSSSSNNNNNNNNSSSSTSSTTSSSSSSSSSSSSSSSSDDPAAPPPPRRRRSSSSSTTTTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS     PPPPPPPPPPPPPPPTTTNNTTTTNTTTTTTTTTTTSSS       SSSSSSSSSSKTTTTTPTNNNKKKKSSSSPPSSSSSSSSSSPPPTTTDTSSSRRRRTTTSSSSSSSYTSHSTSSSISSK        4     
 AYYVVVAAAAAVVVLLLIIYY   LLLIIVV   FFAAA   IIIYYFFSSSYYIIGGLLL    II   LAAAEELLEEEV     IIHHH   FFLLLLL  II       IIIL   LLYYNNNLLLII     IIVVVV  YYVV     LIIYYYVVAAALLNNVVEEEAAAAA         AAAAAYYLL     VVIILLVVHHHLLL   AASS  DDEEEEEEEEL   FF   NNYYVIV  QQAAYVILQIIIIPP  YVLLYYII  LIIILLVVVVVVAAAL  YYISVVVEEVV  A   YEEELLLMMLSS  VYIAALIILLFVALYSLSSILIVITTTTIVILVFLYLALIFLVVFLLLMMAVVITTYYVLLF YYYVA  YIIILLVLLKKLLLVPF LLLLVVLLLLVVYVLLLLFLLLLLIAVALLVLVVVVLAYVIILLVLVKIAVVFAIVVL  PVFFVLLIIILIIIIFFFFLLLTGGGWWLIDVIVVVNLLGGG  VVVIVVVVLLVAVVVVVLLVVQQTTYLLLLLDDTTVVLVVVIIVV  I    VVVYVVLLFAFVLVVVSVVVAIVLLINMLLILLIWWWWWWWWVWWWWWWWWAKKKLIILLLLLQQQQQQQQQQQQQLLFKKSSSSLLLLMMMMMLLLLVVVVVILLLLLLLLLLMMMLLLVVLLLLLLLL     FFFFFFFFFFLLLLLFFFLLLLLLEVVVVVIIIIIIPPP       VVVLLLLLLLLMMMMMLILLLCCCCLLLLAAFLLLLIIIIIIIILLLLLVVVCCCCLLLLLLLFVLWVLVLLFHIKRIQ       H6BB HH
 ALLEEEVVVTTAAA   YYTT   WWWSSGG   FFIII   DDDSSFFPPPLLYYFFSSS    SS   CAAATTYYVVVE     YYGGG   FFYYLLL  YY       YYYF   SSLLTTTFWWYY     WWWWEE  LLEE     FYYVVVEEAAAYYTTQQAAAYYMMM         MMMYYLLAAGGG  EEYYYYAAMMMYYF   TTEE  LLMMMMMMMMW   FF   TTAASYM  VVWWVFYFK  YYVV  LSFFLLYY  FYYYFFTTTTTTKKKF  AAAIWWWAAFF  A   LLLLFFFFFFTT  ALYSSFCCSSYGAFLSILLGVGREYYYYGGEVATLLFAFGTCGGAAAAKKATTYEELLYSST GGGFG  TNYYSSFKKNNKKSVTS NNKKAAVVVSKKLGLFAAKAAAAAFIFSAAA KKTTGFLKTTSSLYRVLVTTLYFGGF  VRTTEAALTTALSSSTTTTKKASVVVEEFELEGLDVVAAAAA  LAALEAADRRVAYSSLLSSKKVVEELNNSAAGGTTLLLTTAFFRR  F    RRFSKKPPTDIFSLLLSIIEAYLLKCTFQKPVSYEEEEEEEEGIIIIIIIIRKKKRDDGGEEEKKKKKKKKKKKKKKKITTSSSSPPPPRRRRRSSSSQQQQQPIIIIIDDDDDQQQSSSKKEEELLLLL     FFFFFFFFFFWWWWWIIIVVAAAAELLLAAPPPPPPSSS       EEEEEEEEEE KKKKKPNLLLEEEEKKKKKKNPPPPQQQQQSSSAAAIESSSSSSSSLLSSSSNKNLIANTLSTNEQEAL      H7B  HH
 EQQEEEWWWQQEEE   NNQQ   EEQPPEE   QQQQQ   EEEEEQQEEEQQAARRQQQ    EE   QEEEDDQQEEEE     QQQQQ   QQQQEEE  QQ       QQQQ   GGQQHHHQEEEE     EEEEEE  QQEE     QQQEEEEEEEEQQHHEEHHHHHDDD         EEEQQQQEEEEE  EEQQQQEEDDDQQQ   RRQQ  EEEEEEEEEED   QQ   HHEEDES  EEEEQEEQN  QQPP  QEQQQQQQ  QQQQQQSSSSSSSSSE  QQESEEEDDDD  E   QEEEQQQQQEEE  EQQEEQTTGGQQEQQPDEESASVAEEEEAQTAPEVDQQESEEEESDDDEELLLQEEEEQEEE AAAEQ  ESQQSSQEEEEEEEETE EEEEDDDDDQEEQEKQSSEDDDDDTEQQDDQ DDLLEEQEDDEEKESDRAQQEEREQQ  ESEEESSRDDRRDDDEEEESSGSSSSNNQEEEEDESEDDAAA  DDDREDDEAATNQDDSSEEEEDDEEEEEEDDQQAAKKELLKRSEE  R    EEEEDDEEEEAQQREEDPPDQQDPDQHSEEEEANEEEEEEEEEEEEEEEEEEEEEEEEAADDDEEEEEEEEEEEEETTPEEEEEEEEEEEEEEEEEEEQQQQQGDDDDDEEEEEDDDEEEEEDDDGGGGG     EEEEEEEEEEQQQQQEEERREEEEDEEETTEEEEEEKKKAAAAAAARRREEEEEEEEEEEEEEPDDDEEEEQQQQEEEVVVVQQQQQEEEDDDEEDDDEEEEEQQEEEEVEEERDEDEDDQQEEQD      H6   HH
 ALLLLLLLLAA      AALLAAAVVAAA     AAAAA   AAALLAAAAALLAASSQQQ    AA   ALLLAAAAAAAL     AAAAA   AAAAAAA  AA       AAAA   NNLL   AVVAA     IILLLL  LLLL   AAAAAAAALLLLLAAVV  IIILLAAA         SSSLLLLLLAAA  LLAAAALLSSSAAA   AALL  AASSSSSSSSL   AA     LLAAV  TTLLLAAAT  AASS  LAAALLAA  AAAAVAAAAAAALLLA  LLVTIIIKKHH  A   LPPPAAAGGALL  ILALLASSGGAAAALTPMMIGIAAAAAAIAAGAAALAAAIAAAAASSSAAAAAAVVLLAAAAALLLAA  LGAAAAAAAIIAAGAHA AAAAAASSSAAALAAAAAASSSSSAAAASSA AAAAAALAAAAAACAKAALLAAAAAA  FAAAKAAAAAPAAAAAAAAAAVSAAAAAAAAAAAAAESSAAA  SAAAAAAAAAAAAAAAALLAAVVVVLAAASSAAHHAAEAAAAAAA  A    AAALAAAAAAAAAAPPGAAAAAALAA AAAAAAASSSSSSSSAAAAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAAVVGGGGAAAAAAAAATTTTAAAAALAAAAAAAAAAAAATTTAAAAAAAAAA     AAAAAAAAAAAAAAAAAAAASSSSAAAAAAAAAAAAKKKLLLLLLLAAAAAAAAAASAAAAAASAAAAAAAAAAAAAAVVVVAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AASAAAAAIAADT      H6BBBHH
 VMMVVVLLLFF      LLLLQQQMMMVV     VVIII   TTTQQAAVVVLLLLRRHHH    LL   LFFFVVMMVVVV     MMTTT   VVLLLLL  KK       MLLM   VVLL   MMMMM     IILLVV  LLVV   SSMLLLLLVVFFFMMMM  IIIMMVVV         VVVLLMMLLLLL  VVLLMMLLVVVMMM   LLLL  VVVVVVVVVVL   TT     LLIRR  VVLLKVRML  MMII  KIMMKKMM  MMMMIMLLLLLLFFFM  LLFIMMMVVLL  I   KVVVMMMLLMLL  SQMLLMVVMMMCIMKVLVVIEIYLLLLLICLESKGKIIIIKMVVASSSIIISSMIIKKIKKKQKKKMM  KLMMLLMIITTIILVQIVVVVVLLSSSMIIKTSMLLLSSSAAQMVLSSA AASSVFLVLLIISMVVALLLAFVVAI  SLKKLLLALLLAAAAKKKKLLDLLLLVVMMCVVLVLLSSVVV  LLLAMLLVVVFARLLVVQQVVIIIILVVISSLLLLLLYSSMIVAA  V  MMAAMMAAFFKVLMTATTVMMLLMLSAV VIVVMIWKKKKKKKKVKKKKKKKKYLLLLIIVVVVVMMMMMMMMMMMMMHHYMMEEEEFFFFIIIIICCCCLLLLLYAAAAAIIIIIVVVCCCLLIIIIIIIIVVVVVVVVVVVVVVVIIIIIIIIVVIIIIVVVVIIVVVVVVIIIIIIIIIIMMMIIIIIIIVIIIIIFLKKKIIIIIIIIAAVVVVVLLLLLVVVIIIIVLLLIIIILIIVVVVLLI VLIVIVPILFAPT      H5BB HH
 KEERRREEERR      KKRREEEQQESS     TTNNN   EEEQQTT   EERRSSRRR    TTAAARNNNRRKKRRRRAA   WWAAA   TTRREEE  RR       WKKCAAASSEE   KQQRR  AAANNNNRR  EERR   AAKEELLLRRNNNRRQQ  NNNEERRR    AAA  KKKEEEEEERRR  RRKKMMEEKKKKKQ   QQEE  RRKKKKKKKKH   TT     KKKCS  KKNNEKRNR  KKKK  EKKKEEKK  KKKWQKAAAAAADDDK  KKKRNNNRRQQ  K   EKKKQQKRREEEKKEKNEEKAAGGKKKKERSRRSTSKRKKKKSKQTQHEKAKESNGQQNEEEKKKNNKDDKKERRNQKKKKK  NNKKEEEEEFFEEQNTKQAAEEEEEEEDEEAQRKEEEEEEEEKNEKEEQ EETTQQPAEEQQRKTIHENNEKQEQE  STKKDEEHEEEHQQQKKKKEEKQQQQRRSAKRQAQEEEESSS  DEEHGEEQEEEQERRHHQQGGEEHHSAAKEENNEEDDRNNKQQQQ  Q  EEQQKGEEKKKREQQHCCVNNIKWADQE QEQEREKHHHHHHHHQQQQQQQQQDFFFVSSGGRRRDDDDDDDDDDDDDSSSEETTTTRRRRAAAAARRRRNNNNNKKKKKKRRRRREEERRREERRRQQQQQTTTTTRRRRRRRRRREEEEERRRSSSSSSEAAAEEDDDDDDDDDEEEEEEEEEEKKKKKKKNSSSSSRDHHHEEEEEEEEKKAEEEENNNNNEEESSSDATTTAAAAKAAGGGGSKN ADEEQRDEESRNQ      H1   HH
 ERRSSSAAASS   HHHKKRRVVVSSKRR  KKKEEKKKRRRKKKRREE   RRRRSSDDDAAAARRQQQKSSSRRHH   SQQ   KKKKKKKKEEEEAAAAAKKKKKK   KKKKKKKSSRREEERSSRREEQQQSSSSSSRRRRSSKKKQQKRREEESSSSSEESS  QQQTT       RRRKKTTTAARRAAQQQ  SSKKRRVV   QQKKKKGGAAQQKKKKKKKKKKSKKKEEKKKEEEEKKS  KKRRRKRKK  KK    RKKKRRRR  KRRKTKSSSSSSSSSK  RRHNSSS  QQKKDKKKRKKKRRKKKKSSEEKRKSSKEEGGEKEKRKKKKKKKRCKKKKKKCKTKTRKERKNRKKKRRRKKELLNEERRTQQNKKKKKK  RRRRQQNKKDDKKRAQLKYYRRQQQQQRKKRKRKEERQQQQQEVAQRRK IILLKRRSQQHHRKRAEQCCKGEKKR  SRQQKQQEQQVESSSQQQQQQKQSSSHHKE RKKCQSRRKKK  RQQEEQQCQQKHRLLEEQQKKEEEERQQLQQKKEEMMSLLEEEAA  E  DDAAKRAARREHSKLEKKKRRAKKQETK EKEKRNQSSSSSSSSKLLLLLLLLAGGGRQQNNAAATTTTTTTTTTTTTQQNTTKKKKKKKKNNNNNNNNNYYYYYQFFFFFYYYYYSSSAAAKKAAARRRRRKKKKKLLLLLLLLLLSSSSSQQQSSSSSSDRRREERRRRRRRRRSSSSSSSNNNYYYYYYYEKKKKKKERRRSSSSKKKKVVQRRRRHHHHHKKKAAANSLLLSSSSEAAEEEERLK KSMIKDSERKAAG       3     
 KCCRRRGGGLL   SSSDDQQGGGDDGGG  EEEHHKKKGGGAAACCHH   CCQQSSGGGEEEENNDDDEGGGFFKK   QDD   GGDDDEEEHHHHGGGEEGGEEEE   GGGGEEEYYCCNNNDDDGGEEDDDEEEEQQEECCKKDDDDDGGGGGGQQGGGKKDD  EEEGG       DDDDD   RRCCEE     QQGGGGGG   KKDEEERRGGEE          EEEEHHEEENNGGNGS    EECNGER  RR    CNGECCGG  DGGGSDKKKKKKKKKE  CCELNNN  GGDDKEEECAAADDGKKEKKEE CGKKDDDFFGGNGCRNRRGPSGRKKKKNGRPSKKCDKGSNHGGINNNGGMGGGGGCCNMMKNCCCGG  CKGGKKRRRGGRRGNNDDGGGGGGNNNKGGCGNNKKSGGGNNENQGKKG GGGGDNCGGGGGNGKGGAGGGKGGGGGGSGKKGKKGGGGGGGGNNNNKKSEGGGRRDG NGGNGPSSGGG  GGGGGGGNGGGHGGGGGCCGGGGGGTGGDNNHHKKGGGGGGGGGG  G  VVGGSCGGNNNGGGGG  SSSGGGSAGG GDGGGKGGGGGGGGGGGGGGGGGGGGGGRGGGGKKKVVVVVVVVVVVVVGGGVVSSSSGGGGGGGGGGGGGGGGGGGGGGGGNNNNNGGGGGGKKGGGEEEEEQQQQQGGGGGGGGGGKKKKKGGGGGGGGGGGGGGGGGGGGGGGGKKKKKKKDDDNNNNNNNGEEEEEGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGDGK EGVGEGLGFRNAR       7     
 WIIVVVIIILL   LLLLLVVRRRLLLIILLVVVLLTTTFFFLLLRRLL   VVLLVVTTTLLLLIIVVVLVVVLLLL   VVV   VVVVVVVVLLLLIIILLLLVVVV   VQQLVVVPPVVLLLLLLLLLLVVVYYYYVVVVVVVVLLLVVLLLVVVVVIIILLLLLLLLLVV       VVVLL   IIIIVV     VVQQVVVV   LLLVVVLLIIVV          YVVVLLVVVLLLLLLL    VVRLLLR  LL    ILLLMMFF  LIIVLYIIIIIIIIIL  RRSTLLL  KKIIWVVVI   LLLIIIIIVV ILIILVVRRLRWLIFAFFSCPLRKKKKMQRSFLPILWLPLLWWIIIILLWLLLLLIILLLLSLLLLL  ILFFLLMLLLLLLIIFLLVVLLIIKKKLFFTWLLLLVIIIIIYVLLKKY LLLLLLILIIKKLYLVLVVVFHLWFLLLKLMMTLLLIIVLLLLMMMMLLSLHHHVVLM LWVLL KKHHH  VIIILIILMMILLLLLLLLLLLLLLRIILNNQQSSLLRLLVLLLL  L  GGLLLVLLLLLLSLKI  MSSYWVMILL LILLLKLLLLLLLLLWLLLLLLLLL   KVVKKLLLTTTTTTTTTTTTTLLNRRIIIILLLLLLLLLIIIILLLLLLVVVVVIIIIIIIIVVVVVIIILLLLLIIIIIWWWWWWWWWWVVVVVNNNIILLLLWVVVFFLLLLLLLLLSSSSSSSTTTIIIIIIIKLLLLLLDLLLLLLLIIIILLLLLLLLLLLLLLLLLLFVIIILLLLIIIIIIILILIFLSLLLSYFLLPI       7B    
 LTTMMMIIILL   TTTLLMMLLLIIVLLSSTTTLLLLLFFF   PPLLLLLEELLGGLLLAAAALLAAAIIII  LL   MGG   LLGGGTTTLLLLIIIAALLTTTT   LLLVVVVVVEETTTIIILLAAGGGFFVVMMLLEEMMSSSGGILLLLLMMIIILLIISSLLLII       GGGSS   IITTVV     MMLLLLLL   LLIAAALLLLII          VTTTLLIIITTLLILI    SSIILIV  LLTT  KIIITTLL  IIILQIIIIIIIIIII  VVIILLL  TTGGLTTTT   IIITTIIIMM SLIIICCSSLLLIVAINNFSLFITTTTLIISFLCVILILLVMMISSSIILVVLMMSSLLLLTIIIII  PIIIVVLIIRRIIVIFV VVVVLLLLLVIITIVVVVYNNNNNILLIPPM LLVVIILLVVVVVIIIIILLLIIMIVFFTIMMIIIIVVLIIIIMMMMVVIIVVVLLVI IMIII LLTTT  ILLIILLILLILLLLVVPPIIMMMMTVVVLLIIIIIIIIIIIIII  I  LLIIILIIAALIIVVL  ISSVLLIKLI IIIIIIIVVVVVVVVMVVVVVVVVV   ILLLLVVVYYYYYYYYYYYYYLLCAAVVVVMMMMIIIIIIIIILLLLLLVVVVVIIIIICCCIIIMMVVVSSSSSLLLLLIIIIIIIIIIVVVVVLLLIIIIIIIIIIIIIIIIIIEEEPPPPPPPIIIIIIIIIIIIIIIIISVVVLLLLIIIILLLLLLLIIIIILLLIIIIILLLVVVVILLFFFFLLLFILVIMLIIILIII       7B    
 PDDDDDTTTSS   KKKPPDD   PPHDDQQEEEPPDDDDDD   DDPPHHHDDSSSSSSSQQRRRRRRRPDDD  GG   DSS   RRSSSEEEPPVVDDDQQMMEEEEEEERSSLGGGSSDDYYYVPPRRQQSSSSSSSDDEEDDDDEEERRPTTDDDDDDDDGGPPQQDDDDD       SSSEE   SSDDDD     DDSSTTDD   GGVEEETTPPEE          SEEESSNNNYYSSDRR    LLEDTEV  KKPP  DDLADDKKGGPKKRSVDDDDDDDDDP  DDVRPPP  TTEEPEEED   VVLMMLDDLL DRNNPSSRRMDPLDSSSSSSSDSEEEEDDSSSSSDEPECTVTPDPPPSSPDDRDDDDEPPTREEEED  DDKKDDDSSGGSSDSPS SSAASSSSSKSSDLDRDDDPPPHHSNENSSP DDDDPEDDSSDDDVDDDPDDADDPPDDDLDSSDDDDSSDDSSSSSSSDDLTPPPNNHD KPSTSCNNEEE  SSSDDSSSDDSYRDDEEDDSSDDDDEPPASSPPNNRRTDDEDDDD  D  DDDDDDDDPPPDSDDE   GGSYRSQDP DGTEINRIIIIIIIIPYYYYYYYYSPPPDDDDDDDDEEEEEEEEEEEEERRSVVLLLLDDDDIIIIINNNNVVVVVDAAAAADDDDDDDDDDDEEDDDDDDDDPPPPPKKKKKKKKKKDDDDDTTTDDDDDDMDDDDDTTTTTTLLLDDDDDDDDDDDDDDDDD VVVVVDGVVVDDDDVVVVDDNDDDDLLLLLVVVDDDDD   DDDDLDDDDDDRN HD KTDDTDDCDP        5     
 YPPEEEEEEVVMMMKKKSSEE   EERTTRRMMMMMAAAPPP   QQMMMMMPPPPSSEEERRRRPPLLLAKKK  PP   ELL   QQLLLMMMMMPPQQQRRPPMMMMMMMPAARLLLPPPPLLLKQQPPRRLLLAAEEEEAAPPEETTTLLVPPEEEEEKKKPPEEEEQQQRR       LLLTT   QQPPEELLL  EEAAPPKK   PPRMMMVVRRTT          AMMMMMMMMLLEERPN    EEPRPR   PPAA  ERKPPPPPSSEPPPQKQQQQQQKKKR  KKRSEEE  PPIIYMMMK   RRKEEKKKMM PPKKKSSKKRKYKEVYIIPLPEKPPPPPKKLPPSKKYKAPDKRKGGGPPYKKPEEEERDDPKPPPHK  KPPPEERPPPPPPSKSP SSVVTTAAARPPPHRREECGGGGGRKRERRK KKKKKKPKTTFFREPQREKKKKRKQKEEEAPPQEERNNVRSSSPPPPEEPNGGGKKSR QKESEKIIAAA  ETTRQTTSEEETPSSKKPPQQEEEEPSSPIIMMEEEEKEEERRPP  R  EEPPKKSSEEPQEQFR   SSAYPESSK RHEKEPRDDDDDDDD EEEEEEEELAAANKKPP   SSSSSSSSSSSSSSSLHHQQQQAAAALLLLLRRRRPPPPPPVVVVVPPPPPPPPRRRSS   AAAAAEEEEEEEEEEQQQQQAAAAA   PPPPPPASSSKKSSSSSSAAA          PPPPPPP EEEEEARTTTDDDDLLLLTTP    PPPPPIIIPPPVE   DDDDSAALLLLRS KP EPAKEELAVK        1     
 EQQAAAKKKQQDDDDDDDDAADDDEETEEEEEEEGGDDDNNN   LLGGDDDEEGGSSEEEEEEEGGDDDSEEE  GG   ADD   GGAAADDDGGGGQQQEEGGDDDDAAAGEEEDDDAAEEQQQDEESSEEDDDEEEEAAEEEEAADDDDDEEEEEEVV   SSEEEESSSAA       DDDDD   EEQQEEEEEDDAAEEGGEE   GGDDDDQQEEDD          DDDDGGGGGQQEEEGG    QQHEGG   GGTTNNEEDEQQEEDDDDDGTEEEEEEENNNN  EESSDDD  KKEEEDDDD     DEEQEEDDDKGDDESSPPGEEDKSMSSGSGREHHHHIEESGELKGEGGERDEMAAAEEETTGKKKKQDDERRRRDD  KLEENNKEEVVEEIEQE HHPPEESSSEEEQDIENNHAAAAASDQDDDE EETTENDEEEAAVSDTETSSTKQEEGDDTDEETNNEEEEEKKKKKKKKKKESSSDDDD NDPIPNNNNNN  SEEEDEETPPSDGYYEEEEKKKKTTEHHNNNEEPPEEEVVLHQNN  K  EENNKDNNDDDDRDTE   SSKEGSKDK KEEDSEGAAAAAAAA NNNNNNNNREEEDVV     SSSSSSSSSSSSSKKETTKKKKNNNNEEEEERRRRDDDDDRLLLLLKKKKK   RRRDD   EEEEEAAAAAEEEEEEEEEE        VVSSSSQKKKKKVVVVVVEEE          KKKKKKKETTTTTEPEEEVVVVKKKKVVK    DDDDDKKKSSSDE   VVVVDDDNNNNKK RQ TSEDTGVHDKE       1     
 ATTTTTMMMHHRRRTTTMMTTSSSQQRTTDDSSSAAHHHTTT   TTTTHHHTTTTSSLLLDDDDTTSSSHQQQHHVV   TSS   TTSSSSSSAAAAAAADDTTSSSSSSSTVVQTTTHHTTLLLHQQTTDDSSSQQ  TTDDTTTTSSSSSQSSTTTTT   VVQQDDDDDLL       SSSLL   LLTTIIHHHSSTTVVTTVV   VVHSSSHHEESS          ASSSTTTTTLLVVTTS    VVTITH   TTTTTTTTHQTTIIGGYIITMHTTTTTTSSSH  SSSSEEE  NNSSASSST   MMHLLHTTTTSTTLLHTTPPTTAHTIKIIFIFLETTTTTTEIFSSTHAHFSHSSIAAALLAVVTLLTTKSSSRTTTHT  TTIIMMKLLPPLLTMKL TTEELLHHHELLTNTDMMTAAAAATTKTAAN TTVVKTTILLSSTHTTTLTTYTVNNRMMSTSSTMMTLLTTMMMNNNNMMSLYYYVVHTNLTTSLAPPHHH  VLLTTLLSMMLATTTVVTTLLLLLLTTTFSSEEEENNITTVVVTT  V  LLTTTSTTMMSMTTSIHH EEFATMETT VEMVQ TMMMMMMMM SSSSSSSSGYYYGTT     DDDDDDDDDDDDDSSEVVMMMMKKKKGGGGGEEEESSSSSEGGGGGTTTTT   AAAVV   RRRRREEEEELLLLLPPPPP        KKSSSSFKKKSSSSSSSSNNN          TTTTTTTNNNNNN GEEERRRRSSSSRRT    TTTTTHHHSSS S   RRRRSAAYYYY   HK RRR RSAVI V       1B    
 GGGAAAGGGGGVVVVVVAAAAVVVRR GGVVVVVAAVVVHHH   GGAAVVVGGAAYYGGGVVVVAAVVVGGGGGGAA   AVV   AAAAAVVVAAAAGGGVVSSVVVVVVVAAAGVVVAAGGLLLGRRAAVVVVV    AAAAGGAAVVVVVAAASSSAA   AARRIIVVVFF       VVVVV   VVGGAAVVVVVAAAAAAGG   AAGVVVGGVVVV          AVVVAAVVVLLSSGAL    AAGGSG   AAWWNNGGGASSGGSSAAAANAVVVVVVVVVG  GGFWRRR  VVVVGVVVG   SSGLLGVVVVVGAFFGEEAATAGGNTLTTSGSNHGGGGGASGTAIGGGGSAAAVAGGGAAGRRTLLGGGAAAVGGGAA  GAGGVVGAAAAAAVGGK AAGGAADDDAAAGAAAVVGAAAVVAGGAAAA AARRAYGAAATTAGAGMAKKAYTAAGNNGAAAGAAMAAAMAAAAAAAVVAAHHHAAAAAAAAAAAGGGGG  AVVMAIIAAAAAAGGTTGGAALLLLGAAEGGRREEVVARRGAAAA  T  MMAAGGAAVVIAAGTMAA AAKGAAAVA AAAAG SPPPPPPPP VVVVVVVVAAAA GG     LLLLLLLLLLLLLIIATTRRRRAAAAGGGGGGGGGNNNNN AAAAAAAAAA   GGGAA   GGGGGPPPPPEEEEEEEEEE        GGTTTTDAAASSQQQQQQQQQ       AAAAAAAAAAGSSSSS SIIIGGGGGGGGGGG         PPPTTT G   GGGGR  GGGG  ADG LGG TDGPA G       2BBBE 
 QLLQQQIII  RRRKKKVVQQRRRAALQQKKRRRLLNNNEEE   LLLLQQQLLLLTTAAARRCCLLQQQILLLSSLL   RQQ   LLQQQRRRLLLLTTTRRLLRRRRRRRLRRLRRRRRLLEEEIAATTKKQQQRR  QQRRLLQQKKKQQALLRRRQQ   LLTTRRRRREE       QQQKK   RRLLRRNNNKKLLRRLLQQ   VVIKKKQQQQKK          LRRRLLKKKEENNILS    QQLMLI LLLLNNEELIILLLLLTTLIILIIKKKKKKNNNL  LLSSLLL  SSKKQRRRL   RRIRRIKKRRRLLNNVVVMMLLNILLRVVFSFKLLLLLQILSLIGLIQILLIFLLLLLTTQEELHHLLKDDLLLLLIL  LQLLRRKTTSS  QIFREVVIIHHEEEL  LILLRRLLLLLLIIKILLMEAAEELL THHLLLILEFIQQLLVMRMLLPLDDERRFHHLFEEEDDDDRRTYEEE  ISRCMILIKVVDDD  IYYFCQQLKKVELLLMMLL  QQQQLVVKRRQQMMMMMQQLVVSS  V  WWSSVLAAKKDCIRLFLL IIRQLILVI VE KI ILLLLLLLL IIIIIIIIIEEE     LLLMMMMMMMMMMMMMPPITTKKKKNNNNQQQQQVVVVQQQQQ PPPPPLLLLL   FFFGGIIIDDDDDIIIIIDDDDDDDDDD        VVVVVVE   LLRRRRRRVVV       IIILLLLLLLTQQQQQ RIIIVVVVIIIILLV         TTTVVV M   VVVVF  KKKK  VVI YFV YEEVS Q      E0B  E 
 RCCKKKRRRRRRRRRRRAARRRRRRRPRRKKRRRPPAAANNN   SSSSRRRRRIIVVVVVRRRRVVRRRRHHHDDAARRRRRR   VVRRRRRRPPMMVVVRRIIRRRRQQQVQQRKKKTTYYRRRRQQLLRRRRRRR  KKRRYYRRRRRRRRVVGGGRRKKKAARRKKRRRRRRRR    RRRRR   RRCCGGIIIRRKKQQVVRRRRRAARRRRRRCCRR          RRRRPPKKKRRRRRIE    RRLRVR NNAADDQQCRRRCCTTRRRDDVRREEEEEEKKKR  RRDDRRRRRKKKKRRRRC   VVRRRREETTKLVKKREEIIERRRCSESSGIGIPKKKKKRPIGMSIRRRGKRPPALLL  RRRENNIINLLK VVVRR  MKTTIIHIIEE  RRCEIKKWWKKKKKR  IRRRIIRPPPPPSRNRPPRKRRRRPE RKKKKRRKVRKNND RRRRVVLKLLVIIRKKPR   LLLLVVPKKKK  PSRDRRLKWGGKKK  RKKRAEELVVKRVSSEERR  KKKKVKKEEEEEKKRRGKKRRRRR  R  SSRRRLRREELAKAKRKK EEHRVKARSERQ VR SPPPPPPPP SSSSSSSSQQQQ     KKKTTTTTTTTTTTTTQQKKKRRRR    RRRRR    TTTTT LLLLLKKKKK   SSSRRRRRRRRRRKKKKKEEEEEEEEEE              T   HHSSSSSSKKK       RRR       PRRRRR LRRRLLLLKKKKSSK         NNN        LLLLR  SSSS  QY  KSR RRSPRRP      E0   EH
 FLLFFFTTTFFYYYYYYLLLLYYYLLLLLYYYYYFFYYYLLL   LLLLYYYLLLLSSLLLYYYYLLYYYLFFFCCLLAAALYY   LLYYYYYYLLLLSSSYYLLYYYYFFFLLLLYYYQQMMCCCLLLLLYYYYYDD  FFYYMMLLFFFYYLLLLLLLLIIILLLLYYYYYLLHHH    YYYFFYYYYYLLLLYYYFFFFLLLLYYYYYLLLSSSIIYYYYYYYYYYYYYYIYYYLLYYYCCLLLLA  YYLLLLLL YYLLPPVVLLLLLLLLVVLLLLVLYYYYYYYYYL  LLSPLLLYYYYYYFYYYL   LLLYYIYYYYYLLLLLIIWWLLFLLIRPPLILLILLLLLLIILLILLFLLLLCHFCCC  FFFLVVLLILLL LLLVV  LILLIIIIILL  MCDIFLLIIIILLLL  LYCLIILCCCCCLCIFHHYFIILLSLLIIIVVCLLFLIVVFFLYYLLLILLLLIILIIVL   LLLLIIVILLL  LIWLYVVILLLLLL  VIILVVVVIIIYLLLLLLL  VVVVFLLIKKIIQQLLLLLILLLLIILIIVVLLLFLLIILLILVMWW LLLFLVYLLNLI IL LLLLLLLLL HHHHHHHHVTTT     SSSFFFFFFFFFFFFFSSATTVVVV    LLLLL    VVVVV AAAAAFFFFF   LLLNNSSSLLLLLLLLLLSSSSSMMMMM              A   LLIIIIIIVVV       CCC       RLLLLL INNNTTTTVVVVLLL         III        TTTTN  TTTT  YL IILG INLVLII      E1B  EH
 LLLLLLPPPRRLLLLLLLLLLLLLMMLLLLLLLLLLLLLTTT   LLLLLLLLLLLPPLLLLLLLLLLLLLLLLIILLLLLLLL   LLLLLLLLLLLLPPPLLLLLLLLLLLLLLLLLLLLLLVVVLMMLLLLLLLLL  LLLLLLLLLLLLLLLLRRRLLLLLLLLLLLLLLLLLLL    LLLLLLLLLLLLQQLLLLLLLLLLLLLLLLLLLLLLCCLLLLLLLLLLLLLLELLLLLLLLVVSSLLP  LLQQLLLL LLLLTTTTLLLLLLLLVVLLLLGLLLLLLLLLLL  LLPLLLLLLLLLLLLLLLLLLAALLLLLLLLLLLLLLLLNNLLLLLFCPPGSGQSLLLLLLSSSLILLLLALLLLLLLL  LVVLLLLLLLLL IIILL  LLLLAALQQLL  LLDQLMMLLLLLLLL  LLLLAALLLLLLLLLLSSMLXXLLLSLLLLLLLLLSLLLLLLLILLLLILLLSAAILLRL   LLLLAATLLLL  LLLLMLLLSPPLLL  LLLLLLLLAAILLLLLLLL  LLLLLMMQLLAAIILLLIILLLLLAALAALLLLLLLLAALLILLLMM MMLLLLNLLLLL VL LAAAAAAAA VVVVVVVVALLL     LLLKKKKKKKKKKKKKLLGIIVVVV    LLLLL    PPPPP AAAAALLLLL   YYYIILLLAAAAANNNNNEEEEEEEEEE              P   TTFFFFFFTTTIIIIIII          YLLLLL RGGGLLLLFFFFDDV         VVV    L   LLLLL  IIII  LV VLIE LLILLIV      E0BBBEH
 EEEEEEEEEGGEEEDDDEEEEQQQ  QEEQQEEEEEEEEYYY     EERRRQQEERREEEQQQQEEQQQEEEE  EERRREQQ   EEQQQEEEEEQQEEERREEEEEEEEEEEEDEEEEE  EEEE  EEQQQQQLL  EEYYEEEERRRLLEEEEEEEEDDDEE  QQQQQEEQQQ    QQQQQQQQQQLLEEEEEQQEEEEEEEEQQQEEEEEELLEEEETTQQQQQQQQEEEEEEEEEEERREEE  KKRRSEEE EEEEEEYYKEEEEEEE  EEEEQEEEEEEEQQQE  RREEEEEQQQQRREEEEPKKKDDEEEEEEKKEKEQQDDDDDEQEEADREEDRDDEPPPPEQEKDESTEEEEEEQQELLLMMESSEMMKKEEEE SSSEQ  PEEESSEEEEE  EETETEE  SS   E  EEEESSELLLLLEQEQEELTEESSIGMESSEEEEEIGEEEESEEEEDDEEEEVSSGHHEGEEEEEEETTEN     ETSVEEEESRR     ESSGTSSETTELEEEGGPP  EEDDPEEDLLEEHHKKESSEEEEETTETTKKEEQMEETTDTEQEGSS   LEEEEEETEL TE EKKKKKKKK YYYYYYYYATTT EE  TTTEEEEEEEEEEEEEEESEEKKKK    QQQQQ    EEEEE TTTTTPPPPP   DDDEETTTAAAAATTTTTKKKKKRRRRR              Q   FFDDDDDDIIIEEEEEEE          RQQQQQ ELLLDDDDEEEEEEE    EEEEEAAA    K   DDDD   EEEE  EE ENDV  EKS KE      H2   HH
 FRRGGGEEEQQGGGGGGAAGGGGG  VAAGGGGGAAGGGMMM     AAGGGPPAATTQQQGGGGAAGGGAGGG  AAGGGGGG   AAGGGGGGAAVVAAAGGAAGGGGGGGAAAAGGGEE     AAAAAGGGGGRR  GGGGIIGGGGGGGAAAGGGGGEEEAAAAGGGGGGGGGG    GGGGGGGGGGIIGGGGGGGGGAAAAGGGGGAAAGGGWWGGGGGGGGGGGGGGTGGGAAGGG  YYAAE  GGEEVAAA GGAAEESSKAAARRAA  AAAAYAGGGGGGGGGA  KKEE   GGGGGGFGGGLGGGPPAGGAGGGGGQAGGADDPPAAYAVDIMMDSDPFIIIIAAFSDAKRAYADAAVVAFFFIIFLLAAAKKVAAA LLLAA  IAAARRA  SS  AFCIKKK  NNFFFV  RAAAHHAFFFFFAYAAGGAKGGLLVQFGKKAAAAAFAIVVAQAAAAPPAAAAFHHANNAAIIIAAAAHHEGFFF  AYFRAIAIYSSFFF  IKKAHKKANNIAAGGAAVV  SSSSLKKIFFAAFFAAALLLSAAANNANNAAAAAVAANNARVAAA   VVAVAIAGAYAQ NA AFFFFFFFF NNNNNNNNLKKK FF  YYYAAAAAAAAAAAAAGGVVVAAAA    IIIII    IIIII AAAAAYYYYY   AAAKKYYYAAAAAQQQQQEEEEEEEEEE              F   AAIIIIIIAAAIIIIIII          EVVVVV VFFFRRRRAAAAAAE    AAAAAFFF    T   RRRR   RRRR  K  F AF  FET IV      H1B  HH
 QKKTTTVVVRRGGGTTTQQTTTTT  QQQKKSSSQQTTTQQQ     QQSSSQQQQQQAAATTTTQQTTTQHHH  QQSSSTTT   QQTTTSSSQQQQLLLRRQQSSSSGGGQQQQTTTTTQQ   QDDQQQQTTTQQ  TTTT  TTSSSTTQQQQQQTTLLLQQDDTTSSSAATTT    TTTTTTTTSSDDRRSSSTTTTQQQQTTTTTQQQGGGDDTTSSSSTTTTTTTTECCCQQTTT  LLQQC  SSAAQQQQ SSQQTTQQQQQQKKQQ  QQQQKQKKKKKKSSSQ  QQTTQQQTTTTSSQSSSKTTTSSQTTQKKSSTQQTTQQQSSQQQQQQEHHSPSSAQQQQQQAPSQSRQQQSQQQQQEEEQQQQQQDDQQQQQQ QQQQQ  QQQQQQQ  AA  QQPQPMM  RRQQQQ  TQQQQQTQQQQQQQQQQQQPQQQQQQQQRRQQQQQQQQSSQQQQQQSSQQQQQQQQRRQQQQQQQQQQQLRYYY  QQCQQLQQEQQQQQ  LRRQQRRQQQQQQQQHHHH  DDDDLLLQQQLLQQEEQQQQQQQQQQQQQDDQQQEQQQQQQLQQQ   HHEQQLQQQQQQ QQ QHHHHHHHH QQQQQQQQFVVVKSS     LLLLLLLLLLLLLAADLLEEEE    TTTTT    TTTTT AAAAASSSSS   VVVAARRRDDDDDQQQQQQQQQQQQQQQ              E   DD      EEENNNNNNN          EEEEEE QRRRAAAALLLLFFQ    VVVVVSSS    PNNNAAAA   RRRR  R  Q HQ  DQE TT      H0B  HH
 YTTSSSAAAVVSSSGGGAASSGGG  LAASSNNNAAGGGLLL     AAGGGLLAAIIAAAGGGGAAGGGIGGG  AAGGGSGG   AAGGGNNNAAAALLLSSAANNNNNNNAAALGGGGGII   IFFAASSGGGFF  SSGG  SSDDDGGVAALLLSSHHHAAFFGGGGGVVGGG    GGGDDGGGGGHHLLGGGDDSSAAAASSGGGAAINNNLLGGNNTTGGGGGGGGQNNNAAGGG  QQMAS  DDAAMIAI TTAAGGLLVLIITTAA  NAAAGIKKKKKKEEET  IITSYYYDDEEEEQNNNDHHHDDISSIGGSSNTAPPMSSEEAEFITSSSSFLFDLLLLLAELLFAPKIYIFAIHHALLLIIVMMAKKEELAAA LLLRE  EAAAVVI  II  AYIDTNN  QQLLLV  NYVEVVKLLLLLAYIE  YTVVMMHYVVQQAAAIASLLVVAELHYIDDEAAAAVVLQQDISSSAAAAIIYQLLL  FVKLYLQLVSSLLL  LQQLVQQRLLLYAIILLQQ  KKQQENNSLLQQMMAAAAAILLVVFFLFFKKVVEGVVIIALVLAI   LLQYALVIALLV LI APPPPPPPP LLLLLLLLDLLLYGG     YYYYYYYYYYYYYLLLIIAAAA    RRRRR    IIIII AAAAAVVVVV   LLLIIHHHVVVVVTTTTTLLLLL                   I   AA      AAAWWWWWWW          IVVVVV VAAAYYYYVVVVYYVIIIIPPPPPHHH    SFFFYYYY   LLLL  Y  Y AV  EI  VS      H1B  HE
 LSSCCCEEESSFFFCCCGGCCCCC  ACCSSFFFAACCCLLL     AAAAAVVAASSAAASSSSAACCCACCC  AAVVVCCC   AACCCFFFAASSAAAGGAAFFFFFFFAAAASSSPPVV   AQQAASSCCCRR  CCCC  CCCCCSSAAAAAACCMMMAAQQSSTTTSSAAA    CCCSSSSSAAQQSSCCCCCCCAAAASSSSSAAAFFFLLSSFFAAAAAAAAAARFFFAASSS  GGTAP  SSRRSAAA AAAAPPLLQA ASSAA  AAAALASSSSSSSSSA  LLPPRRRRRSSSSVFFFKSSSDDACCASSSSSSASSTPPEEAAIASPHPPPAPDLLLLLASLAPALRAVAPAALLAMMMDDAEEATTSSAAAA LLLAS  SAAALLA  II  CLAYAMM  LLMMMA  VLSALLSMMMMMALAA  LAVVEELAMVQQNNSAAVLSGGASFLLADDPAAAVLLLQQAISSSAAAALLPKMMM  SQFQLSGSLQQMMM  SLLLQLLGRRALAVVFFLL  AAAAKMMFMMSSEERRAEESFFAALLFVVMMAASGAALLAQAANF   VVALASMVALFA VA AAAAAAAAA LLLLLLLLVNNNIAASS   SSSSSSSSSSSSSLLQSSLLLL    VVVVV    VVVVV IIIIIAAAAAVVVAAAEEPPPGGGGGHHHHH          VVVVVAAA      S   VV      MMMNNNNNNN          TAAAAA LDDDQQQQVVVVLLMAAAAQQQQQSSS    GKKKQQQQ   LLLLS A  A DL  IL  IL       0B  HE
 TSSIIIVVVAAIIIIIITTIIIII  TTTIIIIITTIIIEEE     TTVVVDDSSTTTTTVVIITTIIITIII  TTIIIIVV   TTIIIIIITTTTVVVIITTIIIIIIITTTTIIIVVKK   TAATTVVIIISS  IIVV  IIIIIIITSSTTTIITTTTTAAIIVVVIIVVV    IIIIIIIIIITTTTIIIIIIITTMMVVIIITTTIIINNIIIIIIIIIIIIIIAIIITTIII  TTATITTIICCFSTT IITTVVEETS TSSTT  TTTTNTIIIIIIIIIT  TTIILLLVVIIIITIIISIIITTTIITIIVVIQTIISVVTTSVTTQVTVVISITVDDDDTVVSITTRSTSITTTTTTTTTTTTTSIISSSTTT EEETV  TTTTDDS  DD  TT SVFF  IITTTT  LTTTNNHTTTTTTTCA  TITTTTTSDTIITTTTSLARTTTLATISTTVTTTLTTSIITSLLLTTTTNNIITTT  TTQTTTYSTTTTTT  TIISTLLFAASTTAAAAAA  IIIIKFFSTTTTIISSTTTTAASSKKAKKLLSSATSSRRTATLTS   AAVTTTTSTEAE KTTTTTTTTTTT EEEEEEEESSSSAGGSS   TTTTTTTTTTTTTTTNNNEEEE    SSSSS    TTTTT EEEEEQQQQQTTTTTTSSKKKVVVVVTTTTT          AAAAAAAA      V   HH      KKKDDDDDDD          IPPPPPKKNNNKKKKTTTTLLQRRRRDDDDDTTT   KSTTTKKKK   KKKKTTV  V TNT SE  TA       2B  E 
 GKKAAAGGGWWAAAAAAGGAAAAA  GGGAAAAACCAAARRR     HHGGGGGGGGGAAAAAAAGGSSSGAAAAAGGAAAAAA   GGAAAAAACCGGGGGAAGGAAAAAAAGGGGAAAAAKK   GGGGGAAAAAGG  AAAA  AAAAAAAGGGGGGAAGGGGGGGAAGGGGGGGG    AAAAAAAAGGDDAAAAAAAAAGGGGAAAAAGGGAAASSVVAAAAAAAAAAAARAAARRGGG  GGGGAKKAAAAQGGG AAVVAAKKSG GKKGG  GGGGIGGGGGGGAAAG  EEAAGGGDDAAAAGAAAKAAAKKGAAGAAAAAKGAAGAAGGGGGGKGGGGAPAKACCCCGGAAAGSVGGGAGGGGGHHHLLGTTGSSKKGGGG CCCGGGGQGGGGGG  KK  GG GANN  KKHHHG  RGGGGGGHHHHHGGGG  GAGGTTGHKGEEGGGGGKGGGGGHGGGGKKGGGGRGGGEERGGGGGGGGGGAAHHH  GGPGGGVGSEEHHH  DKKGGQQVGGGGGGGGGGG  SSSSKRREHH  SSGGGSSGGGGGGGGGGAAGGG GGGGGGGGGG   HHFGGGQGGRGG GGGGEEEEEEEE RRRRRRRRPGGGGGGGG   GGGGGGGGGGGGGGGGNNSSSS    GGGGG    KKKKKGAAAAAEEEEEGGGGGGKKDDDVVVVVKKKKK          GGGGGGGG      V   RRDDDDDDQQQGGGGGGG          GGGGGGSSGGGGGGGGGGGRRPKKKKSSSSSNNN   GMGGGGGGG RRNNNNGGR  S GKG GR GTG       3   E 
 GSSGGGGGGEEGGGGGGHHGGGGG  GGGGGGGGTTGGGCCC     TTGGGSSFFGGGGGGGGGFFGGGGGGGGGAAGGGGGG   FFGGGGGGAASSGGGGGFFGGGGGGGFFFGGGGGGGG   GRRFFGGGGGKK  GGGG  GGGGGGGGFFGGGGGGGGAARRGGGGGGGGGG    GGGGGGGGGGGGGGGGGGGGGFFFFGGGGGAAGGGGEEGGGGGGGGGGGGGGQGGGTTGGG  GGGFAGGGGDDGGFG GGGGGGCCQG GSSFF  GFFFSGGGGGGGGGGG  GGAAQQQGGGGGGGGGGKGGGGGGGGGGGGGGNFGGGAAGGFGGGNALAAGGGCGGGGGGGGGGY IGGGGYGGGFSSSEEGGGFGGKKGHHY GGGGGGGKGFFGGG  DD  GGGNGGG  AASSSG  KGGGGG SSSSSNGGG  GGGGGGGVGGAAGGGGGGGYPPSIGGGGGGAGHHGGGGAAMG   HHHHGGGASSS  GGSGGSGHLGGSSS  SAAGGAAGGGGGFGGGGGG  GGGGKGGNSSQQGGGGFGGGGGGGGGGGGGGGGG GGGGHGGGGG   SSGGFSAGCCGG GGKRTTTTTTTT FFFFFFFFSKKKNNNHH   IIIIIIIIIIIIIRRMEEGGGG    KKKKK    QQQQQKVVVVVRRRRRIIITTTIIGGGSSSSSYYYYY          RRRRRQQQ      G   GGGGGGGGGGGTTTTTTTRRR       KVVVVVNFKKKYYYYKKKKGGGEEEEGGGGGEEE   HTRRRYYYY HHEEEEFRAG A KKESRF PKK      E1B  EE
 LIIVVVVVVLLVVVVVVIIVVVVV  VIILLVVVLLVVVVVV     LLVVVLLLLIILLLLLLLIILLLIVVVVVMMVVVVLL   IILLLVVVLLLLVVVLLIIVVVVVVVVLLVLLLIIYY   VVVLLLLLLLII  VVVV  VVIIILLVIIVVVVVVVVIIVVLLVVVIIVVV    LLLIIVVVVVIIVVVVVIIVVLLIIIIVVVIIIVVVYYVVVVVVVVVVVVVVIVVVLLLLL  VVIIIFFVVVVIVVIILLIIIIRRII IIIIILLLIIVVIVVVVVVIIII  IIIIIIIIIIIVVLVVVIVVVFFIVVIIIIIVIILLIIIIIIILIIILIIV VFEVVVVIIEIVI IILIVIILLIYYYFFLIIVVVIIIIIIIVVVIIIIIIIIIIV  LL  ILVLLFF  LLYYYV  ILVIII YYYYYILVI  LLIILLLLCILLIIILILIVIILIILLVFFIILLLIILLLLI   LLLLIIVLYYY  IIMILLLLFLLYYY  LVVLIVVLIILVLLLLLMM  VVVVIFFFYYLLAAIIMIILIIIILLILLVVIII IILLIILLII   YY LVLTIVVII LLVVFFFFFFFF CCCCCCCCLFFFLLLFF   YYYYYYYYYYYYYLLVVVLLLLVVVVLLLLLFFFFIIIIIVVVVVVLLLLLVVVFFFIISSSVVVVVVVVVV          IIIIIFFFFFVVVVVVVVVVFFFFFFLLLVVVVVVVVVVVVVVVVVFIIIIIVIIIIIIIIFFFFLLLVVVVSSSSSVVVVVVVLYYYVVVV IIIIIIAFVIYVVFVYVIF C I      E5BB EE
 VVVLLLVVVVVLLLLLLIIFFLLL  VIILLLLLVVTTTRRR     VVLLLLLLLLLRRRLLLLIILLLITTTYYTTWWWLLL   VVLLLLLLVVTTRRRLLIILLLLRRRVLLILLLLLII   VTTVVLLLLLII  LLYY  YYYYYLLFTTVVVFFIIIVVTTLLLLLVVLLL    LLLYYCCCVVIIVVTTTYYFFLLIIVVLLLTTILLLVVIILLQQLLLLLLLLTIIIVVLLL  FFVIFFFFFTTRVIIVYYIILLRRVV MVVVVVVMTTVWIAAAAAAFFFI  IIFFTTTIIYYLLILLLVQQQFFIFFIAAVVYVILLIFFLLVIVIVFLFFY YFTLLLLVITYYV VIMIYVFIIIIIISSYMMILLVVIIIVVLLLILLLVIVVIII  YY  IIYGYFF  FFIIII  VVIIVV IIIIIIIIL  VYVVIIITIVFFIIIIVIIVVVTTVVVIFFFVIIIIIIFFVI   TTTTVVMYIII  IIIIVVIIHVVIII  VFFVQLLIVVGVVLLEEVV  LLVVVFFVIIMMAAVVIVVKAKVVVVAVVVVVVL VVIIIVRVII  IVVYIIVVVVSVL IIIILLLLLLLL EEEEEEEEITTT TTVVLLLVVVVVVVVVVVVVTTKQQIIIILLLLGGGGGRRRRIIIIIVKKKKKVVVVVQQQIIIIIIIILLLLL               HHHHHFFFFFRRRRLLLLIIRRRRRRIIITTTTTTTLLLRRRRRRRSYYYYYLKVVVLLLLTTTTYYKTTTTNNNNNQQQRRRMVVVVLLLL VVSSSSLLVFVVLRTVMRI GII      E7   EE
 DDDVVVLLLNNIIILLLDDVVLLL  DDDIIIIIDDLLLDDD     DDLLLLLDDDDVVVLLLLDDLLLDVVVVVDDLLLVLL   DDLLLIIIEEDDLLLLLDDIIIIIIIDDDDLLLDDDDDDDDDDDDVVLLLII  VVLL  MMVVVRRDDDLLLVVIIIDDKKMMLLLLLLLL    LLLVVVVVLLDDLLVVVVVVVDDDDLLLLLDDDIIICCVVVVVVLLLLLLLLFIIIDDLLLDDLLDDDDDVVLLQDDDDIIDDDDDDDD DDDDDDDDDDDEDLLLLLLLLLD  VVDDKKKMMLLDDEIIIDIIIDDDLLDIILLLDDNNDDDDDDDLDDDLDDD DDKDDDDDDKDDD DDEDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD  NN  NEDDIDD  IINNND  DDDDDD NNNNNDDDD  DLDDDDDDHDLLDDDDDDEMIIDDDDDDDDDDDDDDDDLLGD   DDDDDDDIDDD  DH DDIWLDSSNNN  VIIDCTTWDDYDDDDDDSS  DDDDDDDDNNLLNNEEDDDVDDDDDDDDDDDDDD DDNNDDLLDD  DDDEEDIEDNDDH NDDDDDDDDDDD PPPPPPPPADDD TTSSNNNDDDDDDDDDDDDDTTDNNDDDDNNNNDDDDDEEEENNNNNHDDDDDDDDDDNNNHHHIIDDDDDDDD               DDDDDDDDNNDDDDDLLLDDDDDDDDDDDVVVVVVVDDDDDDDDDDEDDDDDDDDDD    KKKKDDDHHHHVVVVVNNNDDDDDNNN     DDHHHHENDDDDDDLNDDDDQDD      E6B  EE
 PPPDDDEEESSQQQPPPPPDDTTT  PPPKKQQQPPPPPPPP     PPRRRPPPPTTPPPKKKKPPPPPPPPPEEPPEEEDPP   PPPPPQQQPPPPLLLKKPPQQQQQQQPPPPPPPTTEEPPPPHHPPKKPPPTT  DDPP  DDEEEPPPPPLLLDDPPPPPEEKKQQQQQQQQ    PPPEEQQQQQRRLLPPPEEDDPPPPLLPPPPPPQQQ  QQRREEQQQQQQQQPQQQPPPPPPPEEPPTPPEEPPPPPPPEEPPTTPPPP PPPPPRRPPPPLPLLLLLLEEEP  EETTEEETTEEEEPQQQPEEEPPPEEPLLQQQPPEEPTTIIPPPPPTPTTTPTPPSSSSLPPTTPPPPPPTPIPPPVVV  PPPPPPPPPPPPPKKKPPPPPVPPIIP  KK  PPTLESS  PPVVVP  PPPPII VVVVVPPPP  PELLPPTVLLPPTTPPLSPPVVLVPPPPPPTLPPYIISPPPP   PPPPVVTPVVV  PS TPPPPCPPVVV  PPPCPPPPAATPPLLPPLL  PPPPPSSLVVTTTTPPPPPGPTLLPPPPPAALLP LLPPPP PIPPPRAAAPPPLPPPHH PPPVPPPPPPPP GGGGGGGGPPPP PPEEPPPPPPPPPPPPPPPPPPLVVAAAATTTTPPPPPPPPPTTTTTPPPPPPPPPPPQQQPPPPP   PPPPP          PPPPPTTTTTIIIKKPPPPHNNNGGPPPPPPSSSKKKKKKKTTTFFFFFFFPPPPPPTPPPP    PPPPPP PPPPPPPPPIIIPPPSAEEE     PPPPPPTERVKMPP NPNLPTPP       3B    
 EEEAAAEEEEEDDDSSSAASSGGG  VNNPPPPPAASSSDDD     IIPPPMMVVDDVVVPPPPVVEEEVSSSAAHHEEESGG   VVGGGPPPAALLPPPPPAAPPPPAAAVVVVEEEDDAAEEEVVVVVPPDDDVV  AAGG  AADDDDDILLPPPSSTTTHHRRPPPPPPPPPP    DDDEEAAAPPRRPPPPPEEAAVVVVPPAAAHHVGGG  SSGGKKSSSSSSSSGPPPAADDDEETTVKENNPPAA VVKEAAIIDDNNEV QEELLKKEVVVLVSSSSSSPPPV  SSEEVVVDDPPKKEPPPESSSNNESSQSSSSADVPPVEEDDVVNEDEVEETQTTSGGGGLVSATAADVGKTENKKIRRR  EDDIRREEVQQADPPPIDDDDGLLFFV  LL  SQTIAHH  EEQQQR  DKLQFF RRRQQIKVV  SSKKDDKKDKAAAALRTDDAGGTKRKTENNEGRREYYDTTAE   RRRRSSNEHHH  VN VNAHSESSQQQ  AEENNDDHLLIVKKKEETT  GGRRDQQIRRKKQQQQVKKSRKRRSSRAAEERRN RRTTRA HADYYRHHVN ADQRERG VIVETTTTTTTT SSSSSSSSVQQQ SSTTKKKTTTTTTTTTTTTTDDRNNEEEEQQQQKKKKKGGGGQQQQQEVVVVVKKKKKRRRSSSGG   RRRRR     TTTTTMMMMMVVVVVPPPNNSSSSKSSSDDKKKKKKRRREEEEEEERRRDDDDDDDSQQQQQNSCCCSSSSKKKKLLDIIIISSSSSEEESSSKVAAASSSSVEEYYYYGAKNRLRP VAKVKEKK       7     
 VTTTTTSSSEETTTRRRTTTTSSS  HTTTTSSSSSTTTTTT     TTSSSKKRRTTTTTTTSSEESSSHTTTTTSSAAATSS   KKSSSSSSTTKKSSSTTAASSSSTTTRKKHSSSTTTTTTT   RRTTSSSVV  TTSS  SSTTTSSGKKSSSTTTTTSSVVTTSSSSSSSS    SSSTTSSSSSSSAATTTTTTTKKRREETTTSSNTTTEETTTTTTSSSSSSSSLSSSTTSSSTTTTNANTTTTLL NNETTTGGTTTTTN YTTKKTTYKKGTHTTTTTTTTTL  SSNNIIISSTTSSGSSSTTTTTTETTNTTSSTTKTTNTTTTNLVETTQTTTNTTSTTTTSLITTFPTETHTFSKRSNNN  KSSNTTTTRTTYSTTTNLLLTTKKSSR  NN  TVTYSTT  TTNNNH  TKTHSS DDDNNSSRL  RSRRSSQTERIITTTAKTSTSSTSTTKHTTNKTTTNNSIITS   TTTTSSTSSSS  SPHTQTTTR  NNN  TTTSSTTTGGTTAQQSSSS  NNSSSTTSNNHHHHSSKTTSSTRRTTSTTKKRRL RRTTTTASTSEESTTDA TSRSTSS SVTTRRRRRRRR FFFFFFFFKTTT TTTTTTTSSSSSSSSSSSSSGGTTTTTTTTTTTTTTTTSSSSHHHHHTTTTTTVVVVVSSSSSSNN   TTTTT     EEEEEDDDDDEEEEESSSTTSSSSFRRRSSTTTTTTTTTTTTTTTTTTTTTTTTTTLTTTTTTTTTTNNNNTTTTTTTSSSSKKKKKTTTTTTTQTTTSSSSTEETTTTRTNASNTANTTSAKATT       8     
 HGGKKKKKKAARRRKKKSSKKQQQ  GGGNNNNNGGKKKGGG     GGGGGHHNNLLRRRDDNNNNQQQSQQQKKLLGGGKQQ   NNQQQNNNGGNNGGGNNNNNNNNGGGNGGSQQQLLRRGGG GGNNNNQQQEE  KKRR  KKKKKQQHNNGGGKKGGGLLRRNNNNNNNSSS    QQQKKKKKNNGGGGQQQKKKKGGNNGGQQQLLSQQQGGGGKKGGGGGGGGGGRNNNGGQQQGGKKSNLHHKKRR SNSNKKNNLLGGNS SGGNNGGYYYDSSNNNNNNKKKS  KKLLRRRNNKKKKLNNNNSSSHHSKKSNNNNKGNKKSLLLLNSSSNLKLLDTDQSHHHHRSGDDNQLSTSDNPTTGGGG  GKKNHHGGSNNNNFFFGSSSNRNNNNG  KK  GNDGKCC  TTGGGH  GTGHDD GGGGGAHSS  AKDDKKTGSGTTGGGSKGGGQQGGGGAGHHLKNNGDDGTTGG   GGGGGGGSGGG  SADGAGGGE  GGG  GTTGSTTGGGGGNEEDDGG  NNKKGCCGGGSSSSGGEKKGGGDDGGGGGKKDDS DDGGNGGGGGSSGGGGS GGGGGGG GGGAGGGGGGGG AAAAAAAAKQQQ AAGGGGGKKKKKKKKKKKKKGGGGGGGGGSSSSSSSSSNNNNTTTTTGGGGGGRRRRRRRRQQQGG   GGGGG     AAAAASSSSSKKKKKAAAKKGGGGGQQQGGGGGGGGQQQRRRRRRRGGGFFFFFFFSKKKKKSGNNNKKKKSSSSGGGRRRRPPPPPGGGGGGHKKKKKKKKGQQAAAADKKKNNGAEGGGGSGGA       8     
 GKKEEEKKKRREEEEEEAAEEEEE  VEEQQEEERREEE        QQQQQGGRREEEEEEEEERREEEHEEEEEEEQQQEEE   KKEEEEEERRKKQQQEEKKEEEEEEEREEHEEEEEQQ    RRQQEEEEEEE  EEQQ  EEEEEEEYEEHHHEEEEEEERREEQQQQQRRR    EEEEEEEEQQRRQQEEEEEEEEEKKHHEEEEEHEEEQQQQEEQQEEEEEEEEKEEEQQEEE  EEVKEEEEEGG VKHKEERREECCKV FKKEEHHFEERHHKKKKKKEEEL  DDEERRREEEEEEKEEEKEEEEEHDDHQQQQEKLEEHEEEEVIGHREKEEN NE GGGGEVSNNESKHQHNEVGGQEEE  CTTETTKKVQQEKEEEHIIIKEEEQQV  GG  ESTQNEE  EEQQQL  LGKHQQ QQQQQRCVV  GEKKAAGLAKEEKKKHDIQEGGQRHRGHEEQDGGIQQQEERK   MMMMRRTQHHH  HRYEGEEED  QQQ  EEEQKEEEKKEERKKCCQQ  FFAAAEEQQQDDEEMMEQQEHHKKQQHQQQQKKV KKQQQEDERKHHRKKQS E KVLDV QYQDGGGGGGGG KKKKKKKKVKKK KKHHDDDRRRRRRRRRRRRRGGEEEKKKKKKKKDDDDDSSSSKKKKKAKKKKKEEEEEKKKRRRPP   EEEEE     QQQQQQQQQQKKKKKSSSHHVVVVMQQQDDEEEEEERRREEEEEEERRRKKKKKKKRQQQQQKQEEEKKKKQQQQKKRVVVVSSSSSQQQIIIEHEEEKKKKEDDQQQQSEKTRQTPKVQLELQKQ       4     
 REERRRKKKRRKKKTTTRRRRRRR  HRRKKKKKQQVVV        RRRRRRRQQKKLLLKKKKKKPPPRVVVKKTTKKKRQQ   KKRRRKKKRRNNRRRKKKKKKKKTTTKRRRKKKKKQQ    RRRRKKRRRHH  RRTT  RRKKKRRRKKKKKRRVVVSSRRKKRRRRRRRR    RRRKKKKKRRQQKKVVVKKRRRRKKKKRRRAARRRRRRRRKKKKKKKKKKKKQKKKRRRRR  RRFGKNNTTRR FKREKKIIKKYYEF HEETTQQHLLRHRKKKKKKKKKW  RRKKRRRKKKKKKRKKKEKKKNNRRRRRRKKTEKKKYKKKKFFRREKLKKK KN LLLLRYIKKRTERRRKRRRRTRRR  RPPYLLEERKKREKKKRFFFERTTRRR  NN  RRKKKSS  VVRRRR  ERKRRR RRRRRKRRY  RIKKPPRQRKIIRRKRKRRQKKTQRRRRNNKKKKRRRRVVQQ   KKKKRRCVRRR  RRRRRQIHS  RRR  HVVKRVVIRRKRRQQQQKK  VVIIESSRRRKKDDRRMPPTRRKKRRRRRIIKKF KKRRKRISRRAAQRRIR Q KKRRR KREKTTTTTTTT HHHHHHHHKQQQKKKPPAAATTTTTTTTTTTTT  VVVPPPPLLLLEEEEEFFFFYYYYYRKKKKKPPPPPSSSKKKII   RRRRREEEEEPPPPPSSSSSEEEEEVVVEEIIIIFHHHLLFFFFFFFFFTTTTTTTFFFFFFFFFFRAAAAALEFFFPPPPQQQQQQEPPPPSSSSSIIIIIIFKKKKPPPPIVVKKKKLKTLEKRLEHLYSRR V      E4   EE
 IMMLLLMMMRRMMMMMMLLLLLLL  LFFMMMMMLLLLLLLL     LLLLLVVLLVVLLLLLLLLLLLLVMMMLLIILLLLLL   VVLLLMMMLLYYLLLLLYYMMMMMMMLLLLIIIVVLLLLL IILLVVLLLVV  LLLL  LLLLLLLLLLKKKLLMMMLLLLMMIIIIILLL    LLLLLMMMLLYYKKVVVLLLLLLVVKKMMMLLLMMMRRRRMMLLMMMMMMMMVMMMLLIIILLLLLHILLLLAAVLLLMMMLLVVLLML LMMLLYYLLLLLLMMMMMMVVVL  LLIIIIIIIMMFFLMMMMMMMLLLLLLMMLLLMLMMIIIVVLLILMIIIIC CLLMMMMYLICCMSMIRICMIIIYLLL  RLLYCCMMILLMMLLLVLLLMFLLVVV  II  LLYLILL  LL   L  MVYLVV LLLLLMLVL  LLIILLIFKLWWLLYVLLMFMMHLLVLVLLILMMLVVMWWLM   LLLLVVFI     ILLFVLFLG  LLL  LLLMLMMFLLLKLLLLLVV  YYYYMLLLLLMMMMHHLLLVLLVVVVLVVCCVVL VVVVLLLLLFSSYLLLV L VLLLL VIMLLLLLLLLL VVVVVVVVVMMMMMMMMLLLAAAAAAAAAAAAAVVMVVVVVVCCCCMMMMMVVVVVVVVVLVVVVVIIIIIIIILLLII   LLLLLKKKKKLLLLLWWWWWYYYYYMMMLLLLLLVFFFVVVVVVVVVVVVVVVVVVYYYIIIIIIIVSSSSSTVIIIIIIIMMMMLLLMMMMIIIIIIIILLLSVLLLIIIILVVMMMMVLVILYISIVILLLL E      E5B  EE
 SSSSSSSSSWWSSSSSSTTSSSSS  PPPSSSSSSSSSSYYY     WWSSSSSTTSSTTTSSSSTTRRRPGGGNNSSSSSSSS   SSSSSSSSWWSSSSSSSSSSSSSSSSSAAPSSSSS  YYY TTYYSSSSSPP  SSTT  SSNNNSSPSSSSSSSSSSSSTTSSSSSSSSSS    SSSTTSSSSSDDSSSSSTTSSAAPPSSSSSSSPSSSQQSSSSTTDDDDDDDDSSSSWWSSSYYSSPSSTTNNTTTPSPSSSPPSSPPSP PSSTTDDPTTSCPSSSSSSSSSP  SSSSTTTSSSSSSTSSSSSSSTTPSSPSSSSSTSSSPTTSSTPPPTTTTTT TTSSSSSSPSSSPFTESDSSSPPC     STTTSSTTPTTSTSSSPPPPTSTTTTP  TT  SSNTSTT  TT   P  TKRPTT    LLSSPS  SSSSTTPNSSSSTTSPSLTTSSSCTNTNTTSSTTDTTTSSWT   TTTTTTTD     PTDSNTPTT  LLL  TSSTTSSPTTSSTSSTTNN  SSSSTTTTLLTTFFNNTTTSTTSSSSTSSGGSSP SSSSTGHSTTPPDLLSP TPSS TT SPSSSSSSSSSS TTTTTTTTTSSSTPPTTTTTTTTTTTTTTTTTTKKSSSTTTTTTTTSSSSSPPPPSSSSSTPPPPPSSSSSDDDTTTSS   SSSSSSSSSSSSSSSNNNNNDDDDDSSSSSPPPPSSSSTTSSSSSSSSSSSSSSSSPPPPPPPPPPSPPPPPSADDDSSSSSSSSDDTPPPPPPPPPPPPPPPNTTTTSSSSSSSTTTTPTPPSTDTTGNTISS T      E2   EE
 TVVVVVFFFLLIIIIIIVVIIIII  QVVIIIIIVVFFFLLL     VVLLLAAVVIIAAAVVIIVVIIIVIIIIILLIIIVVV   VVIIIIIIVVVVLLLVVVVIIIIIIIVVVLIIIVV  MMM AAVVIIIIIAA  VVVV  VVLLLIIMVVLLLVVFFFVVAAIILLLIILLL    VVVLLIIILLIIFFFFFIIVVVVVVFFIIIVVVIIILLLLIIFFIIIIIIIIAIIIVVIIIMMIIKVIYYIIAAVKVVVIIVVIILLVK IVVVVIIIVVVEVIIIIIIIIIS  IIIIIIIIIIIIIIIIIVLLLYYVIIIIIIIIVVFFHIIIIVKVVVIVVVI IYVLLLLVKKIIVFVVIVVVVVVV     IVVVVVIIPVVVVIIINKKKVVVVLLP  VV  LIILLTT  WW   L  VIVVLL      VMPK  IFVVVVVILVWWLLVIVEVLFFVLVIVM  VVVVLLLIWWPV   VVVVLLIL     NV LILTLE       LWWVVWWIVVLLVVVAAII  IIIIVTTL  EEFFLLVVVLVVVVLLVLLVVVVK VVLLVVLLLLLLI  LL LFVV VV LNFVLLLLLLLL LLLLLLLLLLLLLFFVVLLLLLLLLLLLLLLLLLLLLLLLLLLLLLMMMMMLLLLVVVVVLRRRRRFFFFFFFFLLLFFLLLAAAAAVVVVVLLLLLLLLLLFFFFFLLLTTLLLLFPPPLLFFFFFFLLLIIIIIIIIIIFFFFFFFILLLLLLLIIILLLLLLLLLLLLLLLLLLLLIIILLLYFFFFLLLLIIIIIIILFFVPFPLVVPFKRL S      H1BB HH
 EYYYYYYYYLLSSSYYYDDYYYYY  ATTYYYYYDDEEELLL     DDYYYWWTTTTEEEYYYYEEHHHEYYYYYDDYYYYHH   DDEEEYYYDDDDYYYYYEEYYYYPPPEDDDYYYTT  LLL EEHHYYEEEAA  YYYY  YYYYYEEPDDCCCYYYYYDDEEYYYYYYYYYY    EEEYYYYYYYDDSSYYYYYYYDDRRFFCCCDDEPPPLLDDSSYYYYYYYYYYNFFFDDDDDLLYYDESLLYYFFTDEDQYYAATTSSQD EYYDDQQDDDEAQYYYYYYYYYS  YYSTEEEYYYYYYEYYYRYYYMMEYYEYYYYQRDYYDSSTTEDEEQPSSSK KNGSSSSHDSKKDSLSEDKDSSAE     EMMEKKRREEEDRSSSENNNRSDDKKE  KK  QEKAAEE  KK   D  RTADVV      TEEN  QATTVVPSKTKKAASSHNEHSSAEQLKD  THKKKNNEEEDE   KKKKIISD     DDEDVQSQD       QRREDQQSKKQPETTEEFF  KKTTKEEA  EEPPLLDAADNETTNNDSSRRTTD TTNNTDEAAEDDD  FD QKTT NT KHAKSSSSSSSS DDDDDDDDAKKKRPPSSAAADDDDDDDDDDDDDEEAEESSSSQQQQPPPPPGGGGEEEEEGEEEEEDDDDDTTTSSSRRTTTEEEEEEEEEEQQQQQQQQQQVVVVVEEEKKAAAAMRRRRRNNNNNNDDDDDDDDDDDDDEEEEEEESLLLLLQENNNTTTTKKKKKKSEEEEEEEEEEEEAAAEPIIIAAAAPAAKKKKEIDEKSNKLHDKEQF G      H5   HH
 EEEQQQDDDQQEEEQQQEEQQEEE  ADDEEQQQEEEEEQQQ     EEEEEEEEEEEEEEAATTEEEEEVEEEEEEEEEEQEE   EEEEEQQQEEEEQQQAAEEQQQQEEEEEEMQQQEE  EEE NNEEEEEEEQQ  QQQQ  QQEEEEETEEQQQQQEEEEEDDEEQQQEEQQQ    EEEQQQQQQQDDQQEEEQQQQEEDDQQQQQEEAEEERREEEEDDQQQQQQQQDQQQEEEEEQQQQVEEQQEEQQEVEMENNDDEEKKEV VEEEEDDVEEEEVQQQQQQQQQQ  QQEEEEEQQQQQQEQQQEDDDQQMQQVKKQQEEEQQVEEEEDVEVEEEEET TESEEEEKLPTTTPEVEVTAVEQD     DQQEEEEEAEETEDDDIIIIEQEEEEM  EE  DETESEE  KK   T  EDEVEE      EDAV  KLLLQQEESLKKSSEVKQEKEEESEDEV  EKEEDDDEKKEE   EEEEEENV     VEDKDKSNP       KKKEEEETEENRQQQEERR  DDDDEEEE  EEEEEEEQQIEELLDDEDDQQLLT LLDDEERASEEEE  DD KELD EN EVTEEEEEEEEE EEEEEEEEEEEEDVVEEQQQNNNNNNNNNNNNNDDEQQEEEEEEEEDDDDDEEEEIIIIIEVVVVVQQQQQKKKDDDQQQQQEEEEEIIIIIEEEEEEEEEEKKKKKEEEEEAAAAQQQQDDIIIIIIEEEEEEEEEEVVVVVVVVVVETTTTTTEKKKDDDDDDDDSSESSSS     DDDAAATVEEEDDDDEVVEEEEVEEEQEEQDDRSQEE G      H6   HH
 AAAAAAAAASSAAAAAAAAAAAAA  AAAAAAAAAAAAAVVV     AAAAALLAAAAQQQAAAAAAAAAAAAAAAAAAAAAAA   AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA  III LLAAAAAAALL  AAAA  AAAAAAAAAAAAAAAAAAAALLAAAAAAAAAA    AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAQQAAAAAAAAAAAAAALAAAAAAAAIIAAAAALLAALLLAAAAAAAAAAAAAA AAAAAAAAAAAKAAAAAAAAAAA  AAAGLLLAAAAAAAAAAAAAALLAAAAAAAAAAAAAAAAAAAAAAAALAAA ALIAAAAAALAAASAAAAAAAAAA     ASSAAAAAAAAAAAAAAAAAAAAAAAA  VV  AAAAAVV  AA   A  AAAAAA      AAAA  AAAASSAAAAAAAAAAALAAAAAAAAAA  AAAAAAAAAAAA   AAAAAAAA     AAAAAASAA       AAAAAAASAAAAAAAAAAA  AAAAAVVA  KKAAAAASSAAAAAAAAAAAAAAA AAAAAAAAAA  A  AAAAEAA AA AAAAMMMMMMMM MMMMMMMMASSSAAAAAAAAVVVVVVVVVVVVVAAAAAAAAAAAAAPPPPPAAAAPPPPPAAAAAAAAAAASSSAAA  AAAAAAAAPPPPPAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA     AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAIAA Q      H6BBBHH
 IYYMMMMMMFFLLLLLLVVMMRRR  CVVMMMMMVVSSSVVV     VVMMMVVVVMMLLLLLLLFFYYYYSSSMMVVLLLMCC   VVLLLMMMVVVVMMMLLLLMMMMLLLVVVCKKKMM  VVV YYVVMMLLLLL  MMLL  MMMMMLLAVVAAAMMSSSVVYYMMMMMMMMMM    LLLMMLLLMMIIVVSSSMMMMVVLLTTMMMVVYLLLFFVVLLIIMMMMMMMMFMMMVVLLLVVMMLLMLLMMLLVLVYYLLVVIIVVYL YYYVVIIMVVVEYMMMMMMMMMM  MMVIYYYMMMMIIIMMMYMMMLLYMMYMMKKKYVLLCQQIISLIYYQVLLM MMIKKKKMLTVVCFFYIYVCAVVI     LIICVVYYVCCCYKKKYLLLYVVVIIV  SS  VLVNAII  VV   Y  YVLYII      AIVM  LASSIIEVVSTTMMLYVIMFKKLYVVLN  LACCEVVITTVV   CCCCAATK     IVFIVFLFC       FVVLVVVLVVFKLSSVVVV  AASSYIIN  HHMMVVVVVRVLAATTVIIAAAAI AAIIYVFLLL  I  MIMFQAV LV VLISVVVVVVVV LLLLLLLLMIIIVLLIIAAAIIIIIIIIIIIIIIIMKKIIIIYYYYVVVVVLLLLIIIIIIIIIIILLLLLIIICCCVVAAAHHHHHIIIIIIIIIIIIIIILLLLLAAAYYIIIIVYYYLLLLLLLLLLLLLLLLLLFFFQQQQQQQSIIIIIVVIIILLLLVVVVIIVLLLLFFFFFRRRIIIFLKKKLLLLVLLLLLLVKVLYVVIVIIVLFI F      H6B  HH
 RRRKKKKKKRRRRRKKKRRKKGGG  RNNKKWWWRRKKKKKK     RRKKKNNKKRREEEQQQQAARRRKRRRRRCCRRRKRR   SSRRRRRRRRRRRRRQQRRRRRRRRRARRERRRHH  KKK EEKKKKRRREE  KKKK  KKKKKRRQSSSSSKKKKKRREEKKKKKKKEEE    RRRKKKKKKKTTAARRRRRKKRRAATTEEECCKRRRQQRRRRLLQQQQQQQQRRRRKKRRRKKKKSRQEEKKEEDAAKKKKKKHHAAKA QRRRRDDQRRARERRRRRRKKKK  KKQESSSKKKKKKRWWWHKKKQQTKKKKKKKSHEKKKRRHHKDRNKRDRRA AKSNNNNEDSAASSNKRQASKQLL     KDDQAADDQTTSEKKKKNNNDD  EEQ  EE  HQAKKSS  EE   E  HQHREE      QKQD  DKNNDDEEQNEEEEQKGLKQKKERRGAR  NEAASEEQEERS   AAAAEEQQ     QQ EKQQQH       QDDAQEEHGGQARKKRRQQ  AAEEQDDK  EESSEEREEHQRNNAARTTQQNNK NNEENRQEEE  S  KKKQRNK RQ QSGEEEEEEEEE RRRRRRRRKIIIKEEAANNNDDDDDDDDDDDDDAAQEERRRREEEEQQQQQSSSSSSSSSLEEEEEQQQQQRRRQQQGGNNNAAAAASSSSSDDDDDDDDDDEEEEEKKKEESSSSREEEHHSSSSSSSSSKKKKKKKEEEQQQQQQQRQQQQQDRDDDLLLLQQQQAAFRRRREEEEEKKKSSSSQNNNVVVVSEEDDDDSTRADRKDHMADESQ K      H4   HH
 KKKKKKNNNRRRRRRRRAAKKKKK  LKKKKKKKAAKKKKKK     AAQQQSSEERRRRRRRRRAAKKKRKKKRRRRKKKKRR   SSAAAKKKAAVVQQQRRAAKKKKRRRAKKYKKKRR  KKK AAAAKKAAASS  KKKK  KKRRRAARAAEEEKKKKKRRAAQQQQQQQQQQ    AAARRRRRKKKKEERRRRRKKKKAAEERRRRRRRRRQQAARRKKKKKKKKKKSKKKAAAAAKKRRRARRRKKAASRQRKKKEERREEKR RKKKKKKRKKRQRQQQQQQKKKR  KKRRAAADDKKQQKKKKKKKKRRRKKRQQKKRKAKKRRRRRRRKRKRSRRK KRKTTTTRRPKKRLKRKRKRRTSK     MRRKFFKKLRRRKKKKQRRRKK  KKQ  MM  QVKGQEE  HH   R  KTRRKK      DNLR  ARLLRRQQVFSSQQRRQCQRKKGRHCTR  CQNNHKKESSAQ   RRRRRRRL     RC GAQQR        QHHECRRQKKRAAIIHHEE  VVVVKEEE  MMKKKKKKKKLQLLLLHSSAALLR LLLLQRLRQK  R  LRKQHLL GK ERNRRRRRRRRR KKKKKKKKQKKKGRRQQMMMQQQQQQQQQQQQQTTTLLSSSSSSSSQQQQQLLLLQQQQQCRRRRRTTTTTSSSEEEQQRRRRRRRRQQQQQIIIIIAAAAAKKKKKYYYQQSSSSRSSSQQRRRRRRQQQRRRRRRRRRRKKKKKKKKEEEEENKIIIRRRRSSSSQQENNNNTTTTTQQQTTTKHRRRRRRRRRRSSSSERQSDAKSQKTRRKR A       3     
 GGGGGGNNNHHGGGGGGGGGGGGG  GGGKKGGGGGKKKGGG     GGKKKEEGGNNGGGGGKKGGGGGGEEENNGGDDDGGG   GGAAAGGGGGGGKKKQQNNGGGGHHHGGGGGGGNN  GGG RRGGKKGGGGG  GGGG  GGNNNGGGGGHHHGGGGGGGRRQQKKKNNKKK    GGGNNSSSKKNNRRGGGNNGGGGGGHHGGGGGGGGGHHGGHHNNSSSSSSSSQRRRGGNNNGGNNGAGCCNNQQGGCGGGGGGNNKKGG GGGGGGGGGGGDGGGGGGGKKKG  NNGGRRRQQKKGGGGGGDNNNAAGNNGGGGGGEKDDNGGNNGNGGGGGGGNGNCSNNNNGNGNNGGGGGGNGGGGG     GGGGGGKKGGGGKMMMGNNNGG  RRG  GG  GGKGRGG  GG   G  EKGGRR      GGGD  NRGGGGGGGGGGKKEGGGENLLGGNKGG  GGGGGRRGGGGG   GGGGEERG     GD GKHEN        NGGGNGGEGGKGGGGHHGG  GGGGGGGR  KKGGGGGGGGGQGGGGGRRGGGGN GGGGGGGGKG  S  GGDNDGG GG GGHGGGGGGGGG GGGGGGGGGGGGGGGGGGGGNNNNNNNNNNNNNKKSGGKKKKGGGGGGGGGGGGGEEEEEEGGGGGGGGGGGGGEEEPPGGGGGGGGEEEEEGGGGGGGGGGGGGGGGGGGGGGGGGGGGNNGGGGGGGGGKKKKKKKGGGGGGGGGGSKKKKKGGGGGGGGGGGGGKKGDDDDRRRRRGGGGGGGGKKKGGGGGGGNNNNGKGNGGGAGGGDFRE G       7     
 FLLIIILLLQQMMMLLLLLIILLL  LLLLLIIILLLLLYYY     LLLLLLLVVLLQQQLLLLMMLLLYLLLLLLLLLLILL   LLVVVIIILLLLLLLLLVVIIIIIIIVLLHLLLLL  HHH VVVVFFVVVVV  IILL  IILLLVVYLLLLLIILLLVVVVIILLLIILLL    VVVLLLLLLLLLLLFFFLLIILLLLLLIIIVVYMMMRRLLIILLLLLLLLLLLLLLLLIIIYYMMLVITTLLVVILVYXYYVVLLSSLL YLLVVLLYLLYLYIIIIIILLLC  MMIIIIIIILLLLMIIILLLLTTLMMLLLLLLLVLLYLLLLLLLLLIIIIMSMVPRRRRLLHMMI YYWYMILMMV     WLLLLLYYLVVILLLLQLLLLL  LLL  PP  IIL ILL  II   C  LMLCLL    LLQILL  MILLLLLVILIILLLLLLFLLLILLMLY  LVVVLLLAIILI   VVVVLLLI     LL LMWLL   LLL  LIIVLVVMLLLLLLLLLLL  LLLLLLLLLLEEIILLLLLLLLLLLLLLLLLLLL LLLLVLLLLF  LLLMTLLLLI LL LIVVLLLLLLLL HHHHHHHHLLLLLLLLLLLLLLLLLLLLLLLLLLLKIIKKKKLLLLVVVVVLLLLLLLLLIIIIIIMMMMMLLLFFFIILLLYYYYYLLLLLIIIIIIIIIILLLLLLLLFFLLLLLLLLKKYYYYYYLLLYYYYYYYLLLIIIIIIILTTTTTLLLLLFFFFIIIILLLFFFFVVVVVIIILLLIFLLLFFFFYLLFFFFLLLLLLLSNFLIFLL K       8B    
 IIIIIILLLVVFFFLLLVVIILLL  LVVLLLLLLLIIIIII     VVLLLFFVVVVTTTVVLLFFIIIFVVVLLVVLLLILL   VVIIILLLVVIILLLLLIILLLLLLLVVVLIIIVV  III IIVVLLIIIII  IIVV  IILLLIIIVVLLLIIIIIVVIILLLLLMMLLL    IIILLLLLLLIILLIIILLIIVVTTLLIIIVVFFFFVVVVIIMMLLLLLLLLILLLVVIIIIIIIIIVQQLLIILIVFXLLVVVVYYII FIIVVVVIVVFLFIIIIIILLLL  IIVVIIILLLLVVVLLLILLLVVFIIFIIIILIILLFVVVVIIIFIVIVVLFLILIIIIIIFLLV IFLFLVLIII     LLLVLLIILVVVIMMMYIIIII  IIL  VV  IIL IMM  LL   L  IIVLII    LLFILI  IIIILLVIFVLLLLIFIIIIIIILIIIF  VIMMIIIILLFI   TTTTIIII     LI VIIII   LLL  ILLIILLIIIMIVVVIIII  LLLLIMMILLQQLLIIVLLLMMIIIIMLLIIIIL IIIIILILVILLILLVIIVFVV MI IFIIIIIIIIII IIIIIIIIIFFFIIILLVVVLLLLLLLLLLLLLIIILLIIIIIIIIIIIIIIIIIVVVVVVIIIIILLLLLIIIIIIIIIIILLLLLVVVVVCCCCCCCCCCIIIIIVVVIIIIIIVIIIIIVVVVVVLLLIIIIIIILLLVVVVVVVIIIIIIIVLLLYYYYVVVVIIIIIIITTTTTIIIIIILIIIIYYYYILLIIIIVIIILIIILILIILLII       7B    
 DDDRRRLLLSSGGGSSSGGRRRRR  DDDSSRRRGGPPPDDD     SSGGGSSGGDDTTTGGSSSSGGGDPPPRRGGQQQRRR   GGGGGRRRGGGGGGGSSGGRRRRRRRGGGDGGGDD  DDD SSGGSSGGGSS  RRPP  RRRRRGGDGGPPPRRPPPGGSSSSAAALLDDD    GGGRRLLLAADDPPPPPRRRRGGGGPPDDDGGDGGGTTGGDDKKLLLLLLLLDRRRGGGGGDDRRDGDDDRRDDRDDNXRRGGDDEEDD NDDGGDDNGGD DGGGGGGRRRD  RRDDDDDQQRRGGDRRRDGGGDDDRRDGGGGTDGSSDDDDDGDSDDDRDDDCDDASSSSEDSDDD DDDDDDDSSD     DEEGDDDDNDDDDPPPDDDDDD  SSN  SS  ADD DDD  EE   R  DDDHSS    DDDDNN  DGDDEESD DDDDDDDDSDSPPDSDNDD  DDDDDSSDDDGG   DDDDHHDD     STDTDSTSN  DDD  SEEDSEETSSPDGDDKKEE  DDDDDDDTDDLLDDSSGRRPDDEESSDTTDDEED DDSSDAPTDDSSDDDPDVSSED DD TDDDDDDDDDDD KKKKKKKKDNNN DDVVDDDDDDDDDDDDDDDDDDDRRDDDDCCCCDDDDDDDDDKKKKKDPPPPPSSSSSDDDNNNEEDDDAAAAASSSSSNNNNNNNNNNPPPPPEEETTDDDDDSSSDDNNNNNNDDDDDDDDDD   DDDDDDDDPPPPPTDNNNDDDDDDDDNNDMMMMRRRRRVVVDDDEDVVVEEEEITTMMMMRDDDTNNDD NDDCGDD       4     
 GHHPPPPPPLLRRREEEPPPPHHH  TKKPPPPPPPAAAEEE     PPPPPEEPPNNAAAPPPPRRPPPQMMMPPPPPPPPPP   SSPPPPPPPPPPPPPPPPPPPPPPPPGPPRPPPNN  EEE RRPPPPPPPQQ  PPAA  PPPPPPPQSSLLLPPEEEPPRRPPPPPPPPPP    LLLPPPPPPPTTAAIIIPPPPPPGGMMPPPPPEKKKEEPPPPPPPPPPPPPPKPPPPPPPPEEPPQPSSSPPQQPRQEXPPPPNNYYYK QHHPPRRKPPE EPPPPPPQQQE  PPTSLLLQQHHPPSPPPYTTTPPEPPKPPPPPYQPPDSSNNKEGEYNETTPPPKSAAAASDPPPT REGQPTSDDP     LRRVTTYYNIITYPPPAQQQYR  PPN  KK  DVP KEE  RR   R  YSEQPP    KKKANE  SKEERRKT NKKEEDEQPQAEETTQSSE  STPPGPPLKKPQ   PPPPPPRN     QSGSSSNPS  QQQ  SRRRSRRNQQAEPKKQQMM  KKKKREE KKKKKKDDPKKMQQDDNNQRRPPDDE EESSDPHPEQEETPPQARSQEE QQ EHPGVVVVVVVV SSSSSSSSSPPP TTPPVVVMMMMMMMMMMMMMSSPEEAAAAEEEEPPPPPIIIIPPPPPPMMMMMTTTTTMMMPPPEEVVVKKKKKSSSSSPPPPPPPPPPAAAAA   LLAAAAGLLLSSGGGGGGPPPVVVVVVV   LLLLLLLHAAAAAPRPPPQQQQSSSSPPPAAAATTTTTKKKAAASTKKKPPPPSAAPPPPQVKPLALPE  GLAAST      H4   HH
 RQQGGGGGGEEEEEQQQEEGGGGG  QIIGGGGGEEGGGAAA     EEGGGQQEEIIQQQEEGGEEEEEEGGGSSEEEEEGGG   EEDDDGGGEEEERRRGGDDGGGGGGGEEEEDDDII  TTT EEEEGGDDDDD  GGEE  GGSSSDDEEEGGGGGGGGEEEEGGSSSGGGGG    DDDGGGGGGGEEGGAAASSGGEEDDGGEEEEEEEEEHHEEVVAAGGGGGGGGEGGGEEDDDAAGGDDIEEGGEESDEEEGGEEIITTED EQQEEKKEEEE EEEEEEENNNE  GGIIQQQNNNNEERGGGEEEEEEEGGTEEEEGDDEEEIIIIEDKDNISLLIGIDPNNNNGDGIIE EERGLEVDEE     REEEQQNNTKKEEKKKEDDDEG  EEA      SLMSTKK  DD   D  ENGDEE    EEIITK  TAAAEEEE ADDNNTRGQNSDDGEDTTK  VNEEQEESDDED   EEEEEETN     QSERTAETD  EEE  ADDDREEEKKIDESSKKQQ  EEEEAKK EESSEETTEEEDDDNNNNDDDDDDDE EEDDERSRNCKKEEEGREADDH ES ERAQTTTTTTTT SSSSSSSSR    RRSSTTTSSSSSSSSSSSSSQQTEE    AAAAGGGGGEEEE      DDDDDAAAAA   SSSSSTTTLLLLLSSSSSIIIIIVVVVVEEEEE   RRTTTTERRRNNEEEEEEAAAHHHHHHH   NNNNNNNETTTTTKEEEETTTTDDDDEENTTTTSSSSSDDDTTTSKPPPTTTTVQQPPPPEVDVKDE D  DVHEEK      H6   HH
 ATTTTTAAAEETTTCCCFFTTTTT  TMMTTTTTLLFFFTTT     LLVVVVVLLTTDDDLLTTTTVVVMIIITTLLAAATTT   LLVVVTTTLLLLVVVTTIITTTTTTTLLLTVVVTT  TTT SSLLTTVVVVV  TTVV  TTTTTVVIIITTTTTIIILLTTTTVVVMMTTT    VVVTTTTTVVFFAAFFFTTTTLLYYTTIIILLMTTTIIFFRRTTTTTTTTTTGTTTLLVVVTTTTLVTTTTTLLTLWLETTMMTTEETL TTTIIFFTLLM MYYYYYYTTTT  TTTTTTTTTTTLLATTTTPPPTTMTTLYYLLTTVTTMTTTTFLTMTTTTTTFTTACCCCSLFTTD TMGMTDLLLF     AEEFTTTTIDDDTSSSMLLLTH  LLV      MITLSLL  VV   T  TTFTLL    LLYTIL  TLAAEELL DLLMMCMQLTLSSLIMMTM  TQDDILLTLLLT   DDDDLLTT     MSELMLLLQ  LLL  LVVTSVVLLLLMLVVLLVV  TTTTTLL LLLLTTMMIKKLLMHHVVLLLTTHHL QQMMDALLMTKKFLLMTHLMHY LF MLIFSSSSSSSS EEEEEEEEN    KKIILLLRRRRRRRRRRRRRSSA      IIIITTTTTNNNN      NNNNNSSSSS   TTTTTLLLGGGGGSSSSS     TTTTTQQQQQ   GGEEEE GGG  TTTTTTSSSIIIIIII   KKKKKKKFSSSSSRTLLLSSSSSSSSEET    NNNNNIIIEEEA YYYTTTTVGGRRRRVDNHGDS EK SAVRKY      H6B  HH
 AYYAAAAAAVVYYYAAAHHAAAAA  SVVAAAAAHHAAAKKK     HHAAAAAHHGGVVVHHAAYYFFFNAAAAAYYAAAAAA   KKFFFAAAHHYYAAAAAYYAAAAAAAQHHSYYYGG  RRR YYHHAAYYYFF  AAAA  AAAAAYYEHHVVVAATTTYYYYAAAAAAAAAA    YYYAAGGGAAAAAAAAAAAAAHHYYAARRRHHNYYYAARRNNAAGGGGGGGGVAAAHHYYYRRAAYFGGGAALLVYKSISSRRGGEEFY YYYHHFFLHHS NHHHHHHGGGY  AAAGYYYGGGGHHAAAAFAAAGGNAAHHHYYSFCVVKSSGGKYANYAAAAGSGGPIIIITYSGGR FNANGRAAAK     AAAKAAYYLRRRFAAANYYYFM  AAL      AAAAALL  AA   Y  FAAYAA    MMEALH  AARRAAAA HAAAAANMGAFAAKAALAS  AKEELAAAAAHA   EEEELLAA     SAPAMFAYA  MMM  FAAAAVVAAAFVRAAAAAA  AAAAALL MMHHVVAAHAASAARRAAAAAAARRC RRAAKAFHVVSSANNAAGFAKK AV AAAERRRRRRRR EEEEEEEEQ      EESSSVVVVVVVVVVVVVIIA      TTTTAAAAAAAAAHHHHH NNNNNIIIII   SSSQQSSSAAAAAHHHHH     GGGGGRRRRR   AAGGGG AAA  FFFFFFEEEHHHHHHH   RRRRRRRLIIIIIAA   GGGGAAAALLG    SSSSSKKKGGGK TTTGGGGRLLVVVVYF  AGF LA LGPTGG      H5B  HH
 QLLFFFLLLSSQQQLLLEEFFLLL  QDDLLLLLRRAAAQQQ     EELLLRRHHQQGGGHHLLVVAAAQVVVVVSSVVVFLL   NNAAALLLRREELLLLLNNLLLLLLLEDDRDDDQQ  QQQ SSEELLSSSGG  FFRR  FFVVVAATEELLLFFAAAGGEELLLLLLLVVV    AAAIILLLMMDDLLAAAVVFFDDGGLLEEEGGQVVVSSEEQQLLAAAAAAAAKLLLKKSSSRRFFRAQLLEEDDNRNQTLLEEQQQQKR DIIDDDDEDDR QAAAAAAIIIQ  FFQQNNNLLLLEEQLLLMLLL  GFFAAAEELLQSSQQQQQGRQEIQNQQQFQLQDDDDQRFQQD IEQQQDRKQI     QVVDTTLLKDDELNNNKHHHLQ  TTQ      TTQNLHH  KK   A  LRQPNN    EEQTKQ  NLQQIIDD TNNRRTEYKCSNNDDCRKK  QYPPCTTNNNRC   PPPPIIQS     QLMVRSYAK  EEE  SKKSLKKFAASNDDDCCVV  MMAAKHHNQQQQRRDDDFFQCIEELLCLLAAEEH EETTELISRCSSDEEYQISKET CP AGLTEEEEEEEE EEEEEEEER      EEEEETTTTTTTTTTTTT  K      FFFFLLLLLYYYYRRRRRLAAAAAAAAAA   KKKSSEEESSSSSMMMMM     TTTTTQQQQQQQQLLRRRR LLL        WWWEEEEEEE   TTTTTTTDTTTTTID   KKKKCCCC  Q    KKKKKMMMRRRQ LLLKKKKKIIDDDDEN  LST QR  EVDQQ      H6   HH
 REEEEEKKKKKKKKGGGKKEEIII  VRRVVVVVQQQQQVVV     QQAAALLKKRRSSSKKVVKKKKKIQQQVVRRAAAEII   KKKKKVVVQQKKAAAIIKKVVVVVVVKRRVKKKRR  AAA LLKKIIKKKQQ  EELL  EETTTKKAKKPPPEEQQQRRVVIIAAAPPAAA    KKKVVMMMAAMMWWQQQIIEERRKKPPKKKRRVKKKVVKKKKNNRRRRRRRRKVVVQQKKKTTEEVKRYYLLQQESKIIVVKKRRAAES KEEKKQQRKKV VKKKKKKSSSL  EERRLLLAALLKKKVVVENNN  IEEAKKKKVNKTTIRRRRKAKIERERRKGKRSLLLLRAGKKV EIKIKTKMLR     KRRKSSEEFKKAEFFFIAAAER  IIF  AA  KRKKAKK  KK   L  DIQLMM    IICKFA  EAKKRRKT ENNIIQIKYGKLLRMAEDV  RKKKQMMCNNQG   MMMMPPRI     ALAMEKKKK  TTT  KKKSLKKKGGKTKKKDDRR  RRRRQNNKTTAASSLLKQQKTAEEAAAEERREED EEDDRLQEIGDDMMMRKRKAEA AK DIKIVVVVVVVV IIIIIIIIF      KKTTTIIIIIIIIIIIII  S      NNNNVVVVVEEEEVVVVVSTTTTTAAAAA   TTTWWVVVVVVVVQQQQQ     IIIIIAAAAADDDKK     LLL        IIITTTTTTT   VVVVVVVN     CR   AAAAKKKK  I    SSSSSSSS   L KKKLLLLSRRAAAAML  QY  LI  SPDII      H5   HH
 LLLLLLLLLLLLLLLLLLLLLLLL  LIILLLLLLLMMMLLL     LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL   LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL  LLL LLLLLLLLLLL  LLLL  LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL    LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLFLLLLLLLLLLLLLLLLLLLLLLLLLTLLLLLLQQLL VLLLLYYILLL LLLLLLLLLLL  LLLLLLLLLLLLLLLLLLLLL  LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL     LLLLIILLLLLLLLLLMLLLLL  IIL  LL  LLLTLVV  LL   V  LLLIII    LLLMLL  LFLLLLIL LLLIIILLFILLLLIILLL  LLLLLIIILLLI   LLLLIILL     FVTILIILL  LLL  VLLIVLLILLLLLIILLLL  IIIILVVALLYYVVIILLLLLLLLIIMIILLLLL LLIILVILIITTLVVILLVLLL LL LIFLLLLLLLLL FFFFFFFFR      YYLLLLLLLLLLLLLLLL  L      LLLLIIIIILLLLVVVVVRSSSSSTTTTT   LLLEELLLLLLLLQQQQQ     LLLLLVVVVVLLLVV     MMM  LLLLLLVVVLLLLLLL   VVVVVVVL     LL   IIIILLLL  R    VVVVVFFF   L DDDLLLLILLIIIILL  LL  LV  LVRE       H4B  HH
 QSSLLLLLLLLLLLLLLLLLLLLL  TNNLLLLLLLLLLQQQ     LLLLLEELLLLDDDLLLLLLLLLSLLLLLTTLLLLLL   LLLLLLLLLLSSLLLLLLLLLLLLLLLLLALLLLL      QQLLLLLLLQQ  LLLL  LLMMMLLCLLLLLLLLLLKKEELLLLLLLLLL    LLLLLLLLLLSSLLLLLLLLLLLLLLLLLLRRSLLLQQLLLLLLLLLLLLLLLLLLLLLLLQQLLNLLLLLLLLENLSGLLLLLLQQCN TAALLRRTLLA ALLLLLLLLLT  LLLLKKKLLLLLLQLLLSLLL  TLLLLLLLLSLLLSLLLLLNQSSLELLLSLLGLLLLLNGLLLGSSQKLV QQL     QLLLLLLLHLLVSLLLESSSSL  QQH  KK  KKLELLL  KK   S  SQRSQQ    TTLKHN  QLIILLQL IRRAAQELDLLLLMELQQS  LLLLQQQLAALF   LLLLQQLK     CLQLQLLLF  TTT  LKKLLKKLQQLKLIILLLL  LLLLMLLIAASSCCEELLLQMLVVQQLQQLLVVN VVQQLLLLALEESKKMRLLSLI FE WSLSTTTTTTTT SSSSSSSSQ      VVPPP               L      YYYYSSSSSLLLLSSSSSLPPPPPSSSSS   NNNFFPPPSSSSSEEEEE          QQQQQPPPFFLLLL SSS  KKKKKKPPP                 R     MR   AAAALLLL       NNNNNSSSLLLV LLLAAAAFEEEEEEID  S   LAL ILVQ       H0   HH
 DEEEEEEEEEESSSEEESSEEEEE  ALLEEEEEVVEEESSS     VVEEETTSSEESSSSSEESSSSSDEEEEEWWEEEEEE   SSSSSEEEVVSSEEEEEAAEEEEEEESSSDSSSEE      EESSEESSSRR  EEEE  EEEEESSGSSEEEEEEEERRDDEEEEEEEEEE    SSSEEEEEEEDDEEEEEEEEESSSSEESSSRRDSSSVVVVSSEEEEEEEEEEEEEEVVAAASSEENSEQQEERRSNSDSEETTEEDDED AEESSSSESSD DAAAAAAEEEK  EEEEQQQQQEESSDEEEEEEE  DEEDSSSSEESEENEEEESKDDSETEEEDESDEEEENKDEEKDEYDDET DDE     DTTSEEEEEAATQEEENQQQGN  EEE  GG  ADELETT  SS   D  EEQDII    SSRDEG  DEGGSSDS NSSSSQDNLTEEEEDISDV  ENVVE  TDDAT   AAAA  EN     DESEEENEI  SSS  ESSTESSNDDEDAQQVVEE  EEEEQMMLSSEESS  DTTSTKAAEEAEEEEAA  AAEEAEEASTEEDAAEDEEEAA AD DNNRLLLLLLLL FFFFFFFFG      DD                  D      NNNNTTTTTSSSSEEEEETIIIIIDDDDD   LLLDD   DDDDDQQQQQ          EEEEETTTGGNNNN AAA  SSSSSSGGG          DDDDDDDE     DA   DDDDNNNN       IIIIIDDDNNNE NNNEEEEDKKVVVVDN  KD  KDN KSKSD       4     
 TQQAAAAAARRAAAAAAAAAAAAA  VAAAAAAAAAAAA        AAAAAEEAAAAVVVAAAAAAAAAPAAAAAAAAAAAAA   AAAAAAAAAAAAAAAAAAAAAAAAAAAAAPAAAAA  RRR GGAAAAAAAGG  AAAA  AAAAAAASAAAAAAAAAAAAEEAAAAAAAAAA    AAAAAAAAAAPPAAAAAAAAAAAAAAAAAAVVPAAAAAAAAAAAAAAAAAAAGAAAAAAAARRAAPAARRAAGGGPAPDAAAAAA  QP PQQAAGGPAAP PAAAAAAAAAP  AAAAEEEVVAAAAVAAAQAAA  PAAPAAAAAQAAAPAAAAAKFPDAGAAADAPDAAAAAKDAAADDEAEAAEEEA     VKKAGGQQPAAAQAAAPGGGPAPP  P  TT  AQAPASS  TT   Q  QECQDD    RRADPK  EALLKKER L  HHCPAEHRAAAVREEQ  AAAAV  HSSAH   AAAA  A      HASSERGRS  RRR  RTTYA  DPPRHAIIRRAA  GGGGQAAPRRLLKK  RKKCRRLL  RTTAALL  LL  ASMRHQPPPNNVVARPEA RR  SEAEEEEEEEE EEEEEEEED      TT                  A      PPPPKKKKKMMMMFFFFFCIIIIINNNNN   RRRSS   AAAAANNNNN          KKKKKVVVLLDDDD LLL  EEEEEERRR          PPPPPPPR     AQ   GGGGLLLL       TTTTTAAADDDE LLLGGGG AAEEEEPN  KR  PPE ETQTL       6     
 SEEQQQQQQEEEEEQQQEEQQQQQ  DQQQQQQQEEQQQ        EEQQQAAEEQQQQQEEQQEEEEESQQQQQEEQQQQQQ   EEEEEQQQEEEEQQQQQEEQQQQQQQEEESEEEQQ  SSS AAEEQQEEEVV  QQQQ  QQQQQEEPEEQQQQQQQQEESSQQQQQQQQQQ    EEEQQQQQQQTTQQQQQQQQQEEEEQQEEEEETEEESSEEEEQQQQQQQQQQSQQQEEEEE  QQHEQRRQQSSQRESGQQEEQQLLER SEEEESSTEEG REEEEEEQQQD  QQQQKKKQQQQEENQQQEQQQ  SQQSEEEEQEEQQTQQQQEPNSGQSQQQSQTSQQQQQPSQQESSGKGQEKPAE     KQQEQQEESEEEEQQQTPPPDQEE  S  NN  QKQSQDD       K  EYEKSS    DDEKSP  SQQQQQTL E  QQESQEQQQQQNQTAS  QQEE   QAAEQ   EEEE  Q      SQELAQRQY  GGG  Q  QQ  RDDQIEEEQQQQ  QQQQEDDSDDSSQQ  RQQLQQEE  Q  QQEE  EE  ELKAQQLLTLLQSQQTKE QK  THEDDDDDDDD DDDDDDDDI      SS                  L      TTTTTTTTTGGGGIIIIISEEEEEDDDDD   EEEQQ   MMMMMVVVVV          YYYYYLLLLLAAAA FFF  SSSSSSSSS          KKKKKKKG     LE   EEEESSSS       TTTTTLLLAAAF LLLEEEE QQQQQQKD  IR  KSR QEAAV       7     
 SCCAAAAAAVVRRRAAAKKAAVVV  KKKAAAAAQQAAA        QQAAARRRRAARRRRRAARRRRRDAAAAACCAAAAAA   RRRRRAAAQQKKAAAAAKKAAAAAAARRRDKKKAA  RRR RRKKAARRRCC  AAAA  AAAAARRERRAAAAAVVVGGAAAAAAAAAAAA    RRRAAAAAAAEEAAAAAAAAARRRRAARRRCCDRRRRRRRRRAAAAAAAAAANAAAQQKKK  AANRAGGAAGGSDRDSAAKKAAAASD DDDRRLLARRD DRRRRRRVVVE  AAAAMMMAAAAKKNAAACAAA  DAADRRKKACRVVDAAAAKTSDSVSAAAFASFAAAAKAFAAAFNDRDAARNSK     NVVKVVCCSAAASAAADDDDGKRR  S  CC  KSAGAKK       H  SNLHSS    KKRSSD  SAAAVVQV K  VVLDKAIDAAKSLTSA  AKAAN  VEEQV   AAAA  A      DRQRQNQDL  EEE  A  VR  QEETSREELLLL  VVVVGKKGEEQQLL  LIIQLLKK  L  VVKKQ KK  AWDRVVTTEMMFAINDLG LD  DLRAAAAAAAA         D      CC                  D      NNNNGGGGGFFFFNNNNNDSSSSSSSSSS   AAAQQ   NNNNNTTTTT          KKKKKNNNNNNNNN NNN  GGGGGGKKK          AAAAAAAF     DS   IIIISSSS       EEEEENNNNNNS DDDVVVV KKAAAA K  DT  S M IDV K       7     
 YEEAAAAAAEEAAAAAAAAAAAAA  DAAAAAAAAAAAA        AAAAARRAACCYYYAAAAAAAAADAAAAAAAGGGAAA   AAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCCCC  TTT SSAAAAAAASS  AAAA  AAAAAAATAAAAAAAAAAAALLAAAAAAAAAA    AAAAAAAAAAEEAAAAAAAAAAAAAAAAAAAADAAARRAAAAGGAAAAAAAAFAAAAAAAA  AAAACEEAAAACSADTAAAACCNNTS DVVAASSDAAD DAAAAAAAAAK  AACCTTTGGAAAAYAAAEGGG  DSSDAAAAAEAAANCCCCA YDTCCCCAPARPAAAAA PAAAPGDYDAAEYYA     HVVAVVEENAAATAAAD   SAAA  N  II  AYAMAAA       M  TYVMEE    YYAHNC  YAEEVVYP A  LLVDAKQMAAAPQHHD  CAAAK  QQQVQ   AAAA  A      KGTSYTKTM  YYY  A  RN  KEENHAAAQQFF  VVVVDAAMAAQQEE  MAA TEAA  Q  AAAAN AA  ASA LQHHEVVVYAMDQA QE  NDAMMMMMMMM         MYYY   SS                  K  DDDDGGGGKKKKKYYYYMMMMM AAAAAAAAAAHHHRRR     HHHHHEEEEE          LLLLLTTTVVEEEE VVV  DDDDDDGGG          LLLLLLLD     YS   SSSSDDDD       FFFFFNNNDDDQ NNNSSSS DDLLLL M  HN TA Y LAE H       7     
 AWWTTTTTTSSVVVTTTVVTTTTT  NFFSSTTTVVTTT        VVTTTWWVVTTLLLVVSSVVVVVTTTTTTVVTTTTTT   VVVVVTTTVVIITTTSSVVTTTTTTTVVVSVVVTT  MMM LLVVSSVVVVV  TTTT  TTSSSVV VVTTTTTTTTVVRRSSTTTTTTTT    VVVTTTTTTTTTTTTTTTTTTVVVVTTVVVVVTVVVWWVVVVTTTTTTTTTTITTTVVVVV  TTSVTTTSSVVIQVTRTTIITTTTRQ VKKVVLLVVVT TVVVVVVTTTT  TTTTIIITTSSVVPTTTWTTT  TTTTVVVVTWVTTTTTTTV STRSITTTITRITTTTF ITTSISTATTCTEEA     TDDVTTWWKAACSTTTT   VFVV  T  AA  YVTITII       N  IVINFF      VVA   LTTTDDKK T  SSFTFGTCTTVITITY  TFAAA  TSSVT   AAAA  T      IYKFSCICV       C  TF  IVVSPVRRTTAA  TTTT IIM  TTTT  FEERTDCC  N  SSCCP CC  AFWRNN  TSSTSTCNMF NS  VVVFFFFFFFF          DDD   LL                  Q  SSSSCCCCSSSSSTTTTEEEEE SSSSSNNNNNTTTEEE     AAAAARRRRRTTTTT     CCCCCTTTPPPPPPSHHH  FFFFFFVVV                 V     RA   TTTTKKKK       LLLLLAAAPPPKASSSTTTTVVVNNNNT   KT SL M EKE T       7B    
 KEEGGGGGGRRTTTGGGTTGGGGG  KCCGGGGGMMGGG        TTGGGAATTGGQQQTTGGTTTTTKGGGGGKKGGGGGG   TTTTTGGGTTTTGGGGGTTGGGGGGGTTTRTTTGG  KKK RRTTGGTTTQQ  GGGG  GGGGGTT TTCCCGGGGGTTYYGGGGGGGGGG    TTTGGGGGGGGGCCGGGGGGGTTTTRRTTTTTKTTTEETTTTGGGGGGGGGGAGGGTTTTT  GGKTGYYGGGGAKTKVGGSSGGQQVK KSSTTTTRTTK KTTTTTTGGGK  GGGGRRRGGGGTTKGGGEGGG  KGGKTTTTGETGGKGGGGI KKIGAGGGAGVAGGGGT ARGTAKKKKGTTKKL     KGGTGGEEKVVTTGGGK   KTTT  R  GG  VRGHGSS       K  KKTKSS      GKK   KGSSGGKK K  GGTKTHGKGGSAGKKK  GTMMK  GKKTG   MMMM  G      KVKMKKAKN       K  GV  AGGQKTKKGGGG  GGGG SSH  EEGG  KGGRGGKK  G  GGKKK KK  VMKKGG  GEEGKGKKDY GK  KKYQQQQQQQQ          TTT KKKKKKK               K  GGGG    AAAAARRRRKKKKK GGGGGDDDDDVVVEEEGGKKKGGGGGQQQQQGGGGG          WWWPPKKKKGPPPGGVVVVVVGGG          YYYYYYYK     GSTTTAAAAAAAA       EEEEEGGGKKKNKEEEAAAADKKEEEEG GGKN TKKG RKK I       0   E 
 IEEYYYFFFDDGGGFFFGGYYFFF  FGGFFYYYGGFFF        GGGGGGGGGGGGGGGGFFGGGGGGFFFFFGGHHHYFF   GGGGGYYYGGGGTTTFFGGYYYYFFFGGGGGGGGG  MMM GGGGFFGGGDD  YYFF  YYFFFGG GGTTTYYFFFGGGGFFAAAFFAAA    GGGFFNNNAAGGTTSSSFFYYGGGGTTGGGGGGGGGDDGGGGYYSSSSSSSSGYYYGGGGG  YYSGGFFFFGGGNGGVFFGGGGIIVN AMMGGQQGGGG GGGGGGGFFFW  YYGGEEESSFFGGIFFFEFFF  GYYGGGGGFEGFFCGGGGGCNGVGGGGGGGVGYYYYGSGGGGGVGSGGGSDDG     NGGGGGEESGGGAHHHGCCCFGGG  V  VV  GNGGFGG       R  GDGRDD      GAC   EFGGGGDD G  GGGGGGGDHHGGGDEG  GGGGE  GVVGG   GGGG  G      SGLGEDADS       D  GG  ASSNDGGGGGGG  GGGG GGG  GGDD  GGGEGGGG  G  GGGGH GG  GGNEGG  GDDGYGDAGG GG  SGGEEEEEEEE          III EEDDGGG             VVG  KKKK    NNNNNKKKKSSSSS TTTTTSSSSSSSSGGGLLGGGRRRRRIIIIITTTTT          GGGAANNNNDGGGRRFFFFFF             FFFFFFFV     TGVVVDDDDNNNNVV     RRRRRIIINNNDTKKKDDDDGGGGGGGY YLRV VVL  FSY T      E2   E 
 LIIVVVLLLVVYYYIIIYYVVIII  FFFIIIIIYYLLL        HHIIIVVYYIILLLYYLLYYYYYFMMMLLFFIIIVII   YYYYYIIIYYYYIIILLYYIIIIVVVYYYFYYYII  YYY IIYYIIYYYVV  VVMM  VVLLLYYFYYLLLVVLLLFFVVIIIIIIILLL    YYYMMLLLIIIILLLLLVVVVYYYYLLYYYFFFYYYLLYYYYIIIIIIIIIIVVVVYYYYY  VVFYIYYIIVVIFYFLIIYYIIEELF YIIYYFFYYYF FYYYYYYIIIY  VVIILLLIIIIYYLIIILIII  FVVFYYYYVIYVVFIIIIYYLFLIIIIIIIIIIIIIIYVIIFVIFLFIFYLLY     LIIYIIIIFYYFIIIIFYYYLVYY  F  II  FIIVIVV       F  ILIF        YIFY  LIIIIILL L  IIIFVLILIIYLIILF  IVYYI  ILLYI   YYYY  I      FLFLLLLLY       L  IL  LEELLYIIIIII  IIII IIV  IIII  LIILIIVV  I  IIVVY VV  YVLLII  ILLLLVLFVY IV  YVYLLLLLLLL          VVV FFLLVVV             FFQ  IIIILLLLLLLLLVVVVYYYYY      LLLLLIIIFFFLLIIIVVVVVMMMMMIIIII          IIILLNNNNYLLLFFLLLLLL             VVVVVVVIVVVVVFFVVVLLLLVVVVLL     EEEEEFFFNNNIFIIILLLLFIILLLLL FYIY IVE LFLKLF      E1BB EE
 TIIIIITTTAATTTVVVRRIILLL  FEEIIIIIHHLLL        HHSSSTTKKIILLLKKLLTTTTTFLLLIIPPIIIIII   TTTTTIIIHHRRMMMLLKKIIIIIIITRRLRRRII  III YYKKIITTTVV  IILL  IIVVVTTPTTVVVIILLLRRYYIITTTIILLL    TTTIITTTRRLLVVMMMIIIIRRTTVVRRRRRFTTTSSPPTTIITTTTTTTTLIIIYYQQQ  IIIAVIIIILLYMKFVVVIIIIIIVV RIIKKAATKKF FKKKKKKVVVT  IIIIMMMVVVVKKTIIIVIII  FIIFKKVVITKIIFIIIIRITFVIYIIVYVVYIIIIELYVVKYTFTFVKFVTS     TIIKIITTQKKKMTTTFLLLIEKK  P  II  EMIVILL       V  VIGV        NTHT  VIVVIIIS M  IIIFEILIIIIWITVL  IELLI  ISSRL   SSSS  I      TI VTIYIM       I  LL  YVVINTLLIIVV  VVAA LLV  LLTT   IIIIILL  L  VVLLL VV  ALIIVV  LTTITIISVL LL  FMTVVVVVVVV          LLL TTIISSS             HHI  VVVVVVVVLLLLLLLLLIIIII      TTTTTRRRIIIVVIIILLLLLEEEEEQQQQQ          HHHVVIIIIIVVVVVEEEEEE             FFFFFFFEKKKKKEHKKKIIIIVVVVLL     RRRRRTTTIIITTIIIIIIIQKKIIIILYYHRI KLI HI LLT      E4B  E 
 CDDDDDDDDLLDDDDDDDDDDNNN  DDDDDDDDDDDDD        DDDDDLLDDDDLLLDDDDDDDDDDDDDDDDDDDDDDD   HHDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDD  GGG RRDDDDDDDDD  DDDD  DDDDDNNTDDDDDDDDDDDDLLDDDDDDDDDD    DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDLLDDDDDDDDDDDDDDIDDDDDDDD  DDDDCDDDDLLNDDDDDDDDDDPPDD DDDDDDDDDDD DDDDDDDDDDD  DDCNDDDDDDDDDCDDDDDDD  DDDDDDDDDDDDDDNNDDDDCDDNNNNDDDDDDDDDDDDDDDDDDCDDDDDDC     CHHEDDDDNDDDDDDDDDDDDDDD  N  DD  DCDDDDD       D  DHHD        TCND  DDDDHHDS D  DDHDDDSDDD DDDDD  NDDDS  SCCGC   DDDD  D      NW RDDIDD       D  HW  ICCDDDDDDDDD  DDDD DDD  DDQQ   HHDDDDD  D  DDDDD DD  EWDDDCNNDDDCCDDDDD DD  DNTDDDDDDDD          DDD HHDDHHHDDDDDDDDDDDDDDDN  DDDDDDDDDDDDDHHHHEEEEE      VVVVVNNNVVVDDHHHDDDDDLLLLLNNNNNDDDDD     HHHTTDDDDSMMMDDDDDDDD             DDDDDDDHDDDDDDDDDDDDDDDDDDDDD    DDDDDDDDDDDEHSSSDDDDPNNDDDDDSDHRG VDN DD CND      E0B  E 
 PRRPPPPPPPPPPPPPPPPPPPPP  PPPPPPPPPPPPP        PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP   PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP  KKK PPPPPPPPPEE  PPPP  PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP    PPPPPPPPLLTTPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPQPPPPPPPP  PPPPPEEPPPPEPPPRPPPPPPHHRP PRRPP  PPPP PPPPPPPPPPP  PPPPPPPPPPPPPPPPPRPPP  PPPPPPPPPCPPPPPPPPPPPPRPEPPLTLPTPPPPPPTLLPTRPPPLPPPP      PHHPLLRRPPPPMIIIPPPPKPPP  P      VPLPPPP       P  RPPP        RPPP  PPPPHHPP P  IIPPPESPPP VTPPP  PPPPA  SQQPP   PPPP  I      PP PPPPPA       P  SP  PKKPPPPPTTPP  LLVV PPP  VVCC   HHPPTPP  P  LLPPP PP  PPPPIPPPT  PPPPPPP AP  PPRPPPPPPPP          KKK PPPPPPPPPPPPPPPPPPPPPPP  PPPPPPPPPPPPPPPPPQQQQQ PPPPPLLLLLPPPPPPNNPPPRRRRRPPPPPPPPPPPPPPP     PPPPP    NPPPGGPPPPPPPPP          PPPPPPPPPPPPPPPSSSPPPPSSSSPPRPPPPTTTTTPPP   PPPPPSSSSPSSKKKKPPNTPD PPP LL DPP       7B    
 KRRIIIAAAMMYYYLLLYYIIKKK  SRRVVEEEFFHHH        FFQQQAAYYNNGGGYYVVYYYYYNRRRVVFFTTTIKK   YYYYYEEEFFSSHHHVVYYEEEEVVVYYYNCCCSS  FFF SSYYVVYYYEE  IILL  IIEEEYYDYYAAAIIRRRFFGGVVCCCVVCCC    YYYIIVVVCCEEAACCCIIIIYYYYAASSSFFNYYYTTFFYYVVAAAAAAAAGVVVFFYYY  IIAYVAAVVAATVYNKIIYYNNQQKV VRRYY  TYYN NYYYYYYVVVI  IITTSSSVVVVYYKEEEKVVV  NIINYYYYVKYVVNAAAANAKNKAAAALTLNTKKKKVATLLYTTNKNLYVVL      KIIGKKSSNTTYQKKKSDDDKMYY  N  SS  KQIEICC       N  KIVN        LKNG  ITKKIIVD D  YYVNSQNNRRHTVIIN  IVHHM  NRRFN   IIII  Q      KH EVSENN       C  NH  EVVNIYHHLLKK  KKKK RRE  RRAA   VVNVAEE  F  GGEED EE  GENNFSEEE  RKVCEKR FH  YLTHHHHHHHH          HHH AARRAAASSSSSSSSSSSSSSSD  QQQQIIIITTTTTVVVVNNNNN DDDDDEEEEEAAAYYYMMGGGIIIIIPPPPPEEEEEIIIII     EEEAA    LQQQGGKKKKKKTTT          YYYYYYYEHHHHHHRFFFKKKKEEEEKKKYYYYSSSSSKKK   QVMMMKKKKDAATTTTKMVGGA GRE EV EEK       7     
 TSSKKKTTTLLTTTTTTTTKKEEE  VTTRRKKKSSTTT        SSGGGLLTTTTSSSTTHHNNTTTTNNNKKSSTTTKTT   TTTTTKKKSSTTSSSRRTTKKKKEEETTTTSSSSS  AAA SSSSRRSSSTT  KKKK  KKRRRTTGTTTTTKKSSSSSSSRRSSSNNSSS    SSSKKTTTSSTTSSTTTKKKKTTTTTTTTTSSTTTTLLSSTTQQDDDDDDDDTKKKSSTTT  KKTTTTTKKSSTTTTTNNTTTTSSTT SSSSS  TSST TTTTTTTKKKS  KKTTVVVKKKKTTTQQQTKKK  TKKTTTTTKTTKKTTTSSTNTTSTTTTSTSSTNNNNTTTSSTTSTTTSTTTSS     SSSTRRTTNVVTTSSSTTTTTTSS  N  SS  TSSNTSS       T  TSTT        STNT  TTTTSSTS S  NNTTTTSTNNAQTTST  NTSSS  PEESS   TTTT  N      TS STTSCT       T  PN  TGGTSTTTTTSS  RRRR TTN  SSSS   SSTSTSS  S  RRSST SS  KSSTNTHHT  RTHTTTT TS  TSSGGGGGGGG          RRR TTSSNNNTTTTTTTTTTTTTTTK  RRRRRRRRTTTTTTTTTVVVVV EEEEETTTTTTTT   TTTTTTTTTTGGGGGSSSSSSSSSS     TTTKK    TPPPSSVVVVVVIII          VVVVVVVNTTTTTPTTTTSSSSTTTTTTTTTTTTTTTTSSS    TRRRAAAAKSSTTTTTRTTQI ATNTSA TTS       7     
 KGGGGGSSSRRGGGNNNGGGGNNN  QKKNNNNNGGHHH        GGLLLRRGGGGQQQGGNNGGGGGHHHHNNGGSSSGGG   GGGGGNNNGGRRPPPNNGGNNNNNNNGEEHGGGGG  GGG RRGGNNGGGAA  GGGG  GGNNNGGRGGGGGGGSSSGGRRNNMMMNNRRR    GGGNNNNNMMLLGGQQQNNGGEEGGGGGGGGGQGGGRRRRGGNNRRRRRRRRKNNNSSGGG  NNKGGKKNNNNKNGEGNNNNGGGGGK DGGGG  DGGH HGGGGGGKKKK  NNGGKKKNNNNGGKNNNGNNN  ENNTSSGGNGGNNDGGGGGGKEGGGGGRDRGDNNNNKEDRRGDGKKERGGKKS     KGGNGGGGKAAGGNNNQKQQGGGG  K  KK  KKRCGNN       H  GKNQ        DKRG  KGKKGGKG K  DDNQKQSANNGKGKKD  GKGGS  PGGGG   AAAA  K      NG GKSSAG       S  AG  CKKAHGRRGGGG  GGGG HHY  GGGG  RGGAGGKK  G  DDKK  KK  NGGADGTTL  RKSSDKG EA  GGPNNNNNNNN GGGGGGGG MMM GGTTGGGKKKKKKKKKKKKKGGG  GGGGRRRRGGGGGNNNNTTTTTGNNNNNPPPPPDDDKKKGGGGGGGGGGGGGGGGGGGGGGGGG     RRRKK    GGGGRRGGGGGGEEE          RRRRRRRNGGGGGNGNNNRRRRSSSSEEKPPPPHHHHHGGG    KRRRGGGGSGGKKKKGRNEKK GTKQSG LGG       7     
 LRRLLLRRRGGEEEKKKQQLLKKK  DTTAAKKKTTQQQ        SSEEEGGEEDDEEEQQRREEQQQEQQQRRKKAAALEE   QQQQQKKKTTEEEEERRNNKKKKRRREQQEDDDEE  QQQ QQSSKKEEEQQ  LLEE  LLQQQEEGNNWWWFFKKKKKQQKKQQQQQDDD    EEEQQQQQEEEEQQQQQQQLLQQNNQQNNNKKEQQQGGSSEEKKRRRRRRRREKKKSSNNN  LLKQQEELLRRQKNESLLQQEEKKSK ERRKK  EKKE EEEEEEEQQQE  LLQQQQQLLQQNNLKKKRQQQ  ELLKEEKKKTNEEEQQEEKELENQEEEENENNKKKKKENEEKNRELDEKEEER     LMMKKKRRQKKKIRRREQQQREKK  Q  EE  RRDRKII       E  AEKE        EKKQ  EQQQMMEE A  QQKKE KEEEKKHEEE  QQTTT  TEEIQ   TTTT  D      EE KQEKEG       E  KE  ERRERGQQEEHH  KKKK TTR  AAQQ  KMMEEQSS  E  EESS  II  KEEDQKKKE  HMHEDEE EH  GSDKKKKKKKK RRRRRRRR RRR SSEEEEEQQQQQQQQQQQQQEER  DDDDRRRRKKKKKRRRREEEEEREEEEEKKKKKEEEKKKEEEEEEEEEEWWWWWQQQQQQQQQQ     QQQLL    KLLLLLKKKKKKEEE          EEEEEEESKKKKKQQKKKGGGGKKKKSSLDDDDEEEEEEEE    KSSSTTTTDEEEEEEESEEEE KEEPHE TLK       4     
 KQQKKKRRRRRQQQKKKSSKKTTT  QKKRRKKKRRKKK        QQTTTRRKKKKQQQQQRRQQQQQNRRRKKLLRRRKRR   KKQQQKKKRRMMSSSRRKKKKKKKKKQTTKKKKKK  TTT TTTTRRQQQRR  KKRR  KKKKKQQHKKQQQKKRRRQQTTSSTTTKKPPP    QQQRRKKKTTKKRRRRRRRKKTTKKQQKKKQQNQQQQQLLRRLLRRRRRRRRRQQQRRKKK  KKAQRFFRRRRKKTNQKKIIKKSSQK KQQII  KIIN NTTTTTTFFFN  KKRKKKKKKCCNNKKKKQKKK  NKKNTTKKKQTKKNRRKKTKKNQRKRRRKREKKKKKRKKRRVKKNKNRVNKRI     RRRLKKQQTPPVQRRRSGGGQRII  A  II  KKRIKVV       K  QKVR        KKAS  KKPPRRNR P  RRINR RKKKKRRKKN  KRIIT  RKKRR   IIII  R      RI IKKVKR       K  RI  VQQRKRAARRRR  KKKK LLI  IICC  QRRKRIPP  R  KKPP  PP  PVKKRYQQK  RKRKNPS HV  NMTYYYYYYYY WWWWWWWW EEE KKRRRRRRRRRRRRRRRRRREEP  IIIIKKKKDDDDDKKKKRRRRRVKKKKKIIIIIIIIPPPKKRRRRRRRRRRRRRAAAAAAAAAA     PPPTT    KKKKKKEEEEEEKKK          PPPPPPPRDDDDDPEYYYVVVVLLLLIIPVVVVGGGGGKKK   QKKKKVVVVHQQTTTTTKKTK  IGKSTS KIT      E2   EE
 IYYLLLLLLVVIIILLLVVLLYYY  VMMLLFFFIILLL        IILLLVVIICCLLLIILLIIIIILLLLLLLLLLLLII   MMIIIFFFIILLLLLLLIIFFFFLLLIIILIIIFF  VVV LLIILLIIILL  LLLL  LLLLLIITIILLLLLLLLVVLLIILLLLLLLL    IIILLLLLLLVVLLLLLLLLLTTIILLIIIVVLIIIIIIIIIMMLLLLLLLLLLLLIIIII  LLIILLLLLLLLVILYLLIIFFLLYV LYYII  QIIL LIIIIIILLLL  LLVLIIIYYLLIIIYYYYLLL  LLLLIIIILYIVVVLLLLIIILYLLLLYCYLCYYYYLICYFLCYLILYLLMLL     ILLIIIYYMLLLYLLLLTTTYLII  L  MM  MLLILYY       V  YIMV        LLMV  IFLLLLII L  VVMHLLLILLLLMIIL  LLLLV  LLLML   LLLL  Y      VFLVIVIIL       V  LF  LLLVIILLLLLL  VVVV YYV  LLFF  ILLIVIVV  L  VVVV  VV  LLVLVLLLV  VIVVVLI LV  LSLLLLLLLLL IIIIIIII LLL MMMMIIINNNNNNNNNNNNNLLI  LLLLFFFFIIIIILLLLWWWWWEVVVVVYYYYYIIILLLLLIIIHHHHHLLLLLLLLLLMMMMM     IIIVV    VMMMLLLLLLLLVVV          IIIIIIIVLLLLLKIKKKIIIIYYYYIIIVVVVWWWWWVVV   MILLLVVVVILLIIIIVLIIV  VWLIML LEV      E2BB EE
 SDDTTTSSSTTSSSSSSSSTTSSS  TSSSSSSSPPCCC        PPSSSPPSSSSSSSSSTTSSSSSTSSSYYSSTTTTSS   SSSSSSSSPPSSSSSTTSSSSSSTTTSSSTSSSSS  SSS TTSSSSSSSSS  TTTT  TTCCCSSSSSWWWTTRRRSSTTSSSSSCCSSS    SSSYYGGGSSSSSSSSSYYTTSSSSWWSSSSSTSSSPPPPSSPPGGGGGGGGSSSSPPSSS  TTSSS  SSSSGSSTDSSSSSSTTDS SDDAA  SSST TSSSSSSTTTS  NNSSSSSSSSSSSSSSSDTTT  TTTTSSSSSDSSSTSSPPSSSTDSGSSSSSTSTTTTSTTSSSTDTSTSSNNSS     SSSSSSDDYSSSNTTTTPPPDPSS  Y  SS  STSPSSS       T  DHST        STYS  SSTTSSSS T  TTSTAQTSTTSSTSST  GASSP  T  PT   SSSS  T      TPSSNSGSL       S  TP  GSSSTSSSSSTT  SSSS SSP  SSSS  TSSNDTPP  D  SSPP  II  SPTSTSFFS  PSPSTPS HP  MTSTTTTTTTT SSSSSSSSSSSS SSSSSSSNNNNNNNNNNNNNPPT  NNNNTTTTSSSSSNNNNRRRRRTIIIIITTTTTPPPSSSTTDDDSSSSS     SSSSSSSSSS     TTTTT    YTTTSSNNNNNNTTT          QQQQQQQSPPPPPTPPPPSSSSTTTTSSPQQQQLLLLLPPP   SPDDDSSSSSSSSSSSPNYTTS SSSSTI  ST      E1   E 
 YIIVVVVVVAALLLVVVLLVVVVV  YAAVVVVVLLVVV        LLVVVAALLVVVVVLLVVLLLLLYVVVVVLLVVVVLL   LLLLLVVVLLLLVVVVVLLVVVVVVVLLLYLLLVV  VVV IILLVVLLLII  VVVV  VVVVVLLYLLVVVVVVVVLLVVVVVVVVVVVV    LLLVVVVVVVIIVVVVVVVVVLLLLVVLLLLLYLLLAALLLLVVVVVVVVVVIVVVLLLLL  VVYLL  VVLLIYLYIVVVVVVIIIY YIILL  YLLY YLLLLLLVVVY  VVLLIIIVVVVLLYVVVVVVV  YVVYLLLLVVLVVYLLVVLYYYVLVLLVIVVIVVVVVYIVVVIIYYYVVYYYV     YVVLVVIIYVVVLVVVYYYYIVLL  Y  FF  VYVYVVV       Y  IYVY        IYYY  YVVVVVYV V  LLAYVLVLVVVVIYYYYYLVAAL  VLLLV   AAAA  V      YTYVYLLLL       L  VI  L  LYLVVLLVV  VVVV VVY  VVVV  IVVLLLII  L  VVII  LL  VLLLLVYYV  TYVLYLL LY  YLLFFFFFFFF VVVVVVVVLFFF VVLLVVVLLLLLLLLLLLLLYYI  IIIILLLLMMMMMLLLLLLLLLLVVVVVLLLLLLLLIIILLIIILLLLL     MMMMMMMMMM     LLLLL    ALLL  VVVVVV             FFFFFFFIIIIIILILLLLLLLLLLLLLLLLLLLLLLLIII   LILLLLLLLFVVIIIILLVLLY LL IIF          H5BB HH
 KDDEEERRRCCFFFDDDFFEEEEE  QAANNEEEFFNNN        FFDDDHHFFAAHHHFFNNFFFFFMDDDNNFFDDDEFF   FFFFFEEEFFFFDDDNNFFEEEEEEEFFFSFFFAA  WWW YYFFNNFFFYY  EEDD  EENNNFFAFFDDDEEEEEFFYYSSDDDDDDDD    FFFNNEEEDDTTAADDDNNEEFFFFDDFFFFFLFFFHHFFFFDDMMMMMMMMYEEEFFFFF  NNMFQ  DDYYYTFLQDDYYAAWWQM ADDFF  AYYL LFFFFFFDDDH  TTQQYYYDDDDFFKEEEQDDD  LNNLFFFFEQFDDSQQTTFSKLQKYQQHKHQKEEEEGTKHHGKTLKLHGSKKF     KDDFTTNNSFFGKEEESVIITGFF  S  YY  AKHSDKK       Q  QKVR        FKCV  KDVVDDKL L  KKVLAQDEEEFFDKKAVVQGGGL  DFFFD   GGGG  H      HS MKLDEY       T  DS  D  QKFPPQQEE  TTTT KKS  CCEE  EHHIDGEE  E  TTEE  EE  FSSRKDSST  NKDIRQN ET  REFLLLLLLLL VVVVVVVVDLLL KKRRQQQVVVVVVVVVVVVVNNQ  GGGGAAAATTTTTNNNNKKKKKRKKKKKKKKKKEEEEEEEEKKKAAAAAKKKKKSSSSSSSSSS     SSSQQ    VAAA  LLLLLL             EEEEEEEREEEEENDLLLSSSSAAAASSKLLLLSSSSSKKK   AQIIIAAAANNNRRRRDMGEAL LF DKN          H7   HH
 DDDEEEDDDQQQQQEEEQQEEEEE  QQQEEEEEQQEEE        QQEEEQQQQDDEEEQQEEQQQQQQKKKEEQQEEEEQQ   QQQQQEEEQQQQEEEEEQQEEEEQQQQQQEQQQDD  DDD QQQQEEQQQEE  EEEE  EEEEEQQRQQEEEEEEEEQQQQEEEEEDDEEE    QQQEEDDDEEEEEEEEEEEEEQQQQEEQQQQQQQQQEEQQQQEEEEEEEEEEDEEEQQQQQ  EEQQE  EEQQEQQQDEEQQDDEEDY QDDQQ  QQQQ QQQQQQQDDDQ  EEDDQQQDDEEQQEEEEEEEE  QDDQQQQQEDQEEEDDEEQEEQEDQDDKTKETEEEEEDTKKQTEQEERQEEEQ     ENNELLDDDEEQEEEEESSSELQQ  E  QQ  EEKEEDD       E  DEEQ        EEDT  QDQQNNEK Q  DDEDQEEEEEQQEQQEQQEQQQD  EQQQE   QQQQ  K      QS DQDVQD       D  ET  Q  EDQEEKKEE  LLLL DDE  RRYY  EDDDEEQQ  E  LLQQ  QQ  QEQEEEYYE  VDVDQET EE  EEEDDDDDDDD EEEEEEEEDEEE EEDDRRRTTTTTTTTTTTTTTTE  EEEEEEEEEEEEEEEEEDDDDDG     DDDDDEEEDDDRRRRREEEEEDDDDDEEEEEEEEEE     EEEDD    DEEEDDDDDDDD             HHHHHHHEEEEEEELLLLEEEEKKKKEEEDDDDDDDDDQQQ   KQQQQEEEEAEERRRRTEDDEK EE EED          H8   HH
 AAAAAAAAALLAAAAAAAAAAAAA  LAAAAAAAAAAAA        AAAAALLAAAAAAAAAAAAAAAALAAAAAAAAAAAAA   AAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAA  LLL AAAAAAAAAAA  AAAA  AAAAAAALAAAAAAAAAAAAAAAAAAAAAAAA    AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAALLAAAAAAAAAAAAAAAAAAAAAAA  AALAA  AAAAALALAAAAAAAAAAL LAAAA  LAAL LAAAAAAAAAL  AAAAAAAAAAAAAAAAAYAAA  LAALAAAAAYAAALAAAAALALAAAAAAAAAAAAAAALAAAAAMLALAALAAA     VAAAAALLLAAALAAALLLLLAAA  L  AA  AAALSAA       L  CAAL        AALL  ASSSAAAA S  AAALALAMAAAGAAALLLAAAAA  ALLAA   AAAA  A      LSLSALAM        M  AS  A  LAAAAAAAA  AAAA AAL  SSAA  LAAFAAAA  S  AAAA  AA  AALLAALLA  AAAMLAA SL  LAAAAAAAAAA AAAAAAAAAAAA AAGGAAAQQQQQQQQQQQQQAAA  AAAAAAAAAAAAAAAAAAAAAAA     AAAAAAAAAAAAAGGGAAAAAAAAAAAAAAAAAAAA     AAAAA    AAAAAAAAAAAA             AAAAAAAAAAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAA   AAAAAAAAAAAAAAAAAAAAAA AA AAL          H7BBBHH
 IIIVVVVVVRRMMMVVVLLVVLLL  RLLVVLLLMMVVV        MMVVVLLMMVVCCCMMVVMMMMMLVVVVVMMVVVVMM   MMMMMLLLMMIIVVVVVMMLLLLYYYMMMLMMMVV  LLL LLMMVVMMMLL  VVVV  VVVVVMMLMMVVVVVVVVMMLLVVVVVIIVVV    MMMVVVVVVVMMVVVVVVVVVMMMMVVMMMMMMMMMLLMMMMVVIIIIIIIIMLLLMMMMM  VVRMV  VVMMMRLTIVVMMMMMMIR LIIMM  LMML LLLLLLLVVVR  VVVVLLLVVVVMMMMMMIVVV  MVVMLLMMVLMVVFVVTTIRMMIVMVVMVMLVCCCCVRMITYVLKMKLCMMMM     LFFISSLLLMMCLCCCMKKKLLMM  L  MM  VLIVVAA       Q  LMVQ        MLLK  MVVVFFMS I  VVMIANIVCCMFVLMKLLSAVVL  VMMMI   MMMM  A      VLMLLLKL        V  VL  A  IMMVVIIAA  SSSS VVV  VVLL  LMMQIVII  I  AAII  II  MLVRVVMMM  LLYVKIM II  MVMVVVVVVVV IIIIIIIILIII IILLIIIRRRRRRRRRRRRRVVM  VVVVIIIIIIIIICCCCIIIIII     AAAAAIIIVVVLLIIIVVVVVIIIIIIIIIIIIIII     IIIMM    ILLLVVVVVVVV             AAAAAAAAIIIIIIVIIIIIIIIIIIIILIIIIIIIIILLL   IIIIIIIIINIILLLLIILHMI VI MLV          H7BB HH
 NAARRRRRREEKKKLLLKKRRRRR  EKKRRKKKKKAAA        KKRRREEKKNNRRRQQKKQQKKKESSSKKKKRRRRKK   KKQQQTTTKKRRRRRKKSSTTTTSSSKKKGQQQNN  SSS KKKKKKQQQRR  RRRR  RRKKKQQEEERRRRREEEKKKKKKCCCKKRRR    QQQKKKKKRRHHRRAAAKKRRKKEERRKKKKKEQQQEERRKKKKRRRRRRRRRAAAKKKKK  KKEQT  KKKKKEKKDEEQQNNNNDE KTTKK  KKKR QKKKKKKKKKE  KKASKKKKKKKQQDNNNDKKK  EKKKSSQQADKKKKHHDDEKDEEQKHHEAEKAVVVVQRAEEKAEEESEKGTGE     DEEENNEEKKKKAAAAEKKKEKKK  Q  KK  KEEKIEE       G  DANE        TEKR  DVEERRSR D  EENQKNQQAAEQSDDKRRRQNNA  QTTTQ   NNNN  N      GQIEAQQH        Q  QH  Q  QDQKKEERR  NNKK TTK  QQQQ  RKKKQKHH  R  TTHH  QQ  KQQEEQIIH  HEQQDEK HN  GLKQQQQQQQQ EEEEEEEENDDD RRAAEEEDDDDDDDDDDDDDTTD  EEEEGGGGNNNNNVVVVEEEEEE     GGGGGKKKKKKAAEEEEEEEEEEEEEDDDDDDDDDD     RRRRR    RHHHKKFFFFFF             EEEEEEEERRRRRQRQQQRRRRNNNNAAADDDDEEEEEQQQ   RKEEERRRRAEEEEEEERVQR  NK NNG  K       H6   HH
 RKKMMMAAAAAKKKAAAKKMMAAA  RKKEEVVVKKAAA        KKRRRAAKKKKRRRKKEERRKKKRAAAAAKKAAAMKK   QQKKKAAAKKKKRRREEKKAAAAAAAKKKRKKKKK  SSS KKKKEERRRRR  MMKK  MMAAARRQRRAAAMMAAAKKKKEERRREERRR    RRRAAAAARRRRAAAAAAAMMKKRRVVKKKKKRKKKAAKKKKAAAAAAAAAARAAAKKKKK  MMKKQ  MMQQIRKRKQQKKKKSSKR TKKKK  RKKR RKKKKKKAAAK  MMQQKKKNNAAKKRQQQKSSS  RMMTKKKKQKKSSRQQKKKTRRMQIQQRKRFKKKKKKKKRRKKRRNRRQRRCN     NHHRLLKKLKKQQRRRRKKKKNKK  I  KK  EKRKSVV       R  RRAR        KKMQ  RRRRHHRR R  KKVKKACRRREQNRLRRRLKKKQ  CHHRC   KKKK  R      KQNQLRLR        R  CQ  S  RIKKKGGHH  LLLL LLK  NNHH  SHHRRQKK  R  LLKK  KK  QQRRKCNNR  SRRRKKR RK  RNRAAAAAAAA KKKKKKKKQEEE KKNNLLLKKKKKKKKKKKKKNNR  RRRRSSSSRRRRREEEEQQQQQS     SSSSSMMMCCCTTLLLKKKKKQQQQQMMMMMVVVVV     IIIQQ    RQQQSSKKKKKK             IIIIIIISRRRRRSKQQQGGGGSSSSKKKRRRRKKKKKEEE   SDFFFSSSSKQQKKKKRFKQQ  AQ RQS  YR       1    H
 SNNGGGGGGGGDDDNNNGGGGGGG  CGGGGGGGEEGGG        GGRRRGGDDGGGGGDDGGDDDDDCGGGGGGGGGGGGG   DDGGGGGGEEGGGGGGGGGGGGGGGGDDDCEEEGG  QQQ GGGGGGDDDDD  GGGG  GGGGGEECDDGGGGGGGGGGGGGGGGGGGGGG    EEEGGGGGGGSSGGGGGGGGGGGDDGGDDDGGSDDDGGGGDDGGGGGGGGGGHGGGEEDDD  GGCGR  GGQQGCDCGKKDDGGNNGC CGGDD  CGGC CEEEEEEGGGC  GGGGGGGGGGGEESEEEGGGG  CGGCDDDDGGDGGCSSGGDCSCGSGSSGNGKNKKKKGCNGGGNRCCCGGCCCR     CGGGGGQQCGGGGGGGCCCCRGDD  C  QQ  TAGCGGG       S  GCNS        GSCC  CGGGGGCN G  RRNCGKNSGGRGDCCCCCGGGGG  NSSEN   GGGG  C      CESGCSGS        S  ED  G  SSGGGGGNN  GGGG GGC  GGGG  EGGCDNGG  D  GGGG  GG  GGSCRNSSN  GSGSCDG DG  CGGGGGGGGGG DDDDDDDDGNNN GGGGGGGGGGGGGGGGGGGGKKG  GGGGGGGGGGGGGDDDDRRRRRD     GGGGGGGGYYYGGRRRGGGGGRRRRRGGGGGGGGGG     GGGGG    GGGGGGNNNNNN             KKKKKKKGNNNNNGGGGGGGGGGGGGGGGGGGGRRRRRGGG   NGGGGGGGGGGGGGGGKGGGG  GN GGT  GD       4     
 MLLIIIVVVVVLLLLLLLLIILLL  VWWVVLLLLLLLL        LLLLLVVLLLLLLLLLVVLLLLLVLLLIILLLLLILL   LLLLLLLLLLFFVVVVVHHLLLLMMMLLLVLLLLL  YYY QQLLVVLLLLL  IILL  IILLLLLVLLLLLIILLLLLLLVVVVVVVLLL    LLLIIIIIVVLLLLLLLVVIILLLLLLVVVLL LLLVVLLLLIILLLLLLLLILLLLLLLL  IIRLI  VVLLLRLMLVVLLLLMMLR KLLLL  RLLV MLLLLLLLLLG  VVILQQQVVLLLLMLLLIVVV  MIIILLLLVILLLVVVLLLTMIMLLIILMLLMLLLLWTMLLHMVIMTLRVRRI     LIILLLVVLLLRVVVVVKKKLWLL  V  MM  WDLRLLL       R  VIIQ        LILK  KLLLLLRL L  FFVVYKLIVVIFLRRIVVIFLLV  LYYLL   LLLL  L      VLYIKVII        I  LM  L  TILLLLLLL  LLLL LLK  LLLL  ILLVLILL  L  LLLL  LL  VAEVFLYYL  LMYTQII LK  ISLLLLLLLLL VVVVVVVVLIII LLFFIIITTTTTTTTTTTTTIIL  VVVVLLLLIIIIIVVVVLLLLLL     IIIIIVVVLLLKKIIIIIIIILLLLLLLLLLRRRRR     LLLLL    LLLLRRVVVVVV             CCCCCCCLIIIIIFIDDDLLLLVVVVYYVRRRRLLLLLKKK   ILVVVLLLLY  YYYYFVFLL  IL FLD  LI       6B    
 VIIVVVVVVIIIIIVVVIIVVIII  CLLIIIIIVVVVV        VVVVVIIIIVVLLLIIVVIIIIIQVVVVVVVVVVVII   IIIIIIIIVVVVVVVVVIIIIIIFFFIIIEIIIVV  FFF LLVVIIIIILL  VVVV  VVVVVIIRIIVVVVVVVVIILLVVVVVIIVVV    IIIVVVVVVVVVVVVVVVVVVIIIIVVVVVVV IIIIIVVIIVVVVVVVVVVLIIIVVIII  VVIII  VVLLVIILVVVVVVVLLVI TIIVV  VVVR KIIIIIIVVVK  VVIIIIIVVVVVVVIIIIVVV  IVVTIIIIVIIVVTIIVVITVTIIVIIILVILVVVVMVLIIVLITVIIILKRL     VIIIVVIILIILIVVVTAAAILVV  F  MM  LFIIVLL       Q  IKIK        VFFV  KTLLIIKI L  VVLRMIIIVVLTITKTHHIILLI  IIIVI   IIII  I      RIMLPLII        L  II  I  LSIVVVVII  IIVV LLI  VVII  IIILLVII  L  IIII  II  IIMAIIIIV  IIFLRIF LI  RLMIIIIIIII LLLLLLLLVIII LLLLIIIVVVVVVVVVVVVVIIL  LLLLVVVVLLLLLVVVVFFFFFV     IIIIIFFFYYYLLIIILLLLLFFFFFIIIIIIIIII     YYYVV    IVVVLLLLLLLL             LLLLLLLLVVVVVIIVVVVVVVLLLLLLIIIIIFFFFFLLL   LLLLLVVVVI      ILLIV  VF VIV  II       7B    
 EDDGGGGGGDDVVVGGGPPGGGGG  DYYGGGGGDDSSS        DDGGGDDVVDDRRRVVGGVVVVVDGGGGGPPGGGGVV   VVVVV   DDPPGGGGGII    GGGVPPDVVVDD  TTT SSLLGGVVVKK  GGGG  GGGGGVVDVVRRRGG   PPSSGG   GGGGG    VVVGGEEEGGDDGGGGGGGGGPPVVGGEEEPP VVVDDSSVVGGGGGGGGGGR   DDVVV  GGEVD  GGRRREVDDGGPPDDPPDE DDDPP  DPPD DVVVVVVGGG   GGDDKKKGGGGLLEVVVNGGG  DGGDVVLLGQVGGDDDDDEEED DRDDEDEDDDDDDPEDEDDDDDEDENDDDD     EDDEDDDDDDDNDEEEDDDDDPPP  D  RR  PDDDDDD       E  DDSE        VDSD  DDDDGGDD D  SSNDSISSDDDDADDDDDTPNNS  SNNDS   NNNN  E      DSDTDQDH        Q  T   D  HDVEETTDD  EEEE DDD  DDNN  DDDNSSRR  S  EERR      D HHSSDDD  DEDQDHP  D  KDVDDDDDDDD DDDDDDDDDNNN   DDNNNIIIIIIIIIIIIIDDH  DDDDDDDD     HHHHNNNNND     DDDDDDDDEEEAADDDDDDDDNNNNNDDDDDDDDDD     DDD       DDD  DDDDDD             DDDDDDDDDDDDDDDDDDDDDDTTTTDDTDDDDDDDDD      NDDDDDDDDS      TD  D  DD  DV  DD       7     
 D  PPPEEEQQRRRSSSRRPPPPP  SYYPPGGGRRRRR        RRPPPEERRKKPPPRRPPRRRRRPSSSPPAAPPPPRR   RRRRR   RRRRPPPPPRR    KKKRTTPRRRKK  EEE AARRPPRRRAA  PPPP  PPPPPRREKKPPPPP   WWAAPP   PPPPP    RRRPPEEEPPNNPPEEEPPPPTTKKPPKKKVV RRREEKKRRPPKKKKKKKKP   QQKKK  PPPRQ  PPPPPPKK WWRRKKEE P EQQEE  KEEP PKKKKKKPPPS  PPHQPPPPPPPRRAKKKKPPP  PPPPKKKKKKKPPKEEKKKPEP EPEENPNEPPPPPQPPNNKPEKEKNKKPPR     EEEKSSQQLNNKQRRRPPPPEAEE  V  PP  YFRTYKK       E  KDRA        ECVP  INKKEEPR R  PPKDESSEIIRRAPIKPPEQKKE  SAARS   KKKK  E      PNASPEND        E  S   M  EQRRRSSQQ  PPRR KKI  HHEE  QEEEPPPP  P  EEPP      K EGPYAAN  TEEEPER  I  KIECCCCCCCC PPPPPPPPPDDD   PPPPPIIIIIIIIIIIIIPPP  PPPPPPPP     HHHHPPPPPP     PPPPPSSSKKKPPAAAPPPPPPPPPPPPPPPAAAAA     SSS       PPP  PPPPPP             LLLLLLLVKKKKKPQVVVPPPPPPPPPPPTTTTPPPPP      PPKKKAAAAK      P   S  PP  PA  PP       6     
 I  EEEEEEEEEEEEEEEEEEDDD  EEEEEEEEPPEEE        PPEEEEEEE  GGGDDEEDDEEEEEEEEEEEEEEEEE   EEEEE   PPDDEEEEEDD    EEEEEEEEEE    GGG EEDDEEDDDDD  EEEE  EEEEEDDPDDEEEEE   DDEEEE   EEEEE    DDDEELLLEEIIEEEEEEEEEEEDDEEEEEEE EEE  EEEEEEEEEEEEEEG   AAEEE  EEHED  EE  GHDE EEEE  EE H NSSDD  EEEE TEEEEEEEEES  EEEDEEEEEEEEEKSSSNEEE  EEEDQQQQESEEEKDD  GAKQ DGSSTITAIDDDDEVITTEISKNKTDDLLQ     GDDGQQSSDKKDDSSSDSSSSEDD  D  EE  EHTEEEE       G   YEG        EHSN  TEEEDDSI E  EEEEEESERRYAKASTDDDEDDS  SHHPT   DDDD  S      TENEQNNK        N  S   N  GEDDDRRDD  RRQQ EEE  CCDD   EEERKEE  R  DDEE      N PDESHHI  QGENEEA SE  RPNHHHHHHHH         STTT   EEKKKNNNNNNNNNNNNNVVE  VVVVSSSS     EEEEDDDDDD     DDDDDDDDEEEEERRRSSSSSDDDDDEEEEEDDDDD     NNN            KKKKKK             EEEEEEEINNNNNTAAAAVVVVRRRRVVETTTTVVVVV      SDNNNQQQQK      E   R  IE  DG  KA       6     
 T  FFFLLL  HHHLLLQQFFVVV  TAALLIIILLLLL        LL   LLHH  TTTHHLLHHHHHTLLLLLQQLLLFHH   HHHHH   LLHH   LLHH    TTTHEETHHH    RRR VVHHLLHHHVV  FFLL  FFLLLHHSHHHHHFF   QQVVLL            HHHLLTTT  TTLLLLLLLFFEEHH  QQQQQ HHH  LLHHYYLLLLLLLLT   LLHHH  FFTHM  LL  TTHT YYYY  EE T TSSYY  SYYT THHHHHHLLLT  FFMMVVVLLLLHHSHHH LLL  TFFTHHHHW HLLTMM  HTTT MTMMSTSTTQQQQSSTSATT TTTATTSSK     T  HTT  STTTGDDDTTTT TYY  C  LL  ATYSWTT       T   TMT        HTST  TFKK  ST E    MTNSSTEEKTISTTTTMNTTM  STTPS   VVVV  Q      SLT STTT        T  S   T  TSHMMLLLL  TTEE TTS  TT       TIL    L            T TT STTT  TTMTTAQ ST  GNH                 SEEE   TTTTTSSSSSSSSSSSSSKK   SSSSSSSS     TTTTTTTTTR     SSSSSRRRSSS  TTT     TTTTT     TTTTT                    SSSSSS             TTTTTTTTTTTTTTTKKKSSSSVVVVGGGKKKKSSSSS      TSNNNSSSSN      G   T  AS   E  ST       7B    
 G  KKKTTT  GGGHHHGGKKFFF  GGGHHFFFAAQQQ        AA   LLGG  AAAGGHHGGGGGGRRRHHAAHHHKGG   GGGGG   AAGG   HHGG    YYYGAAGGGG    KKK AAGGHHGGGAA  KKHH  KKHHHGGGGGGGGKK   TTAAHH            GGGHHEEE  GGHHQQQHHKKAAGG  AAAAA GGG  AAGGHHMMMMMMMMA   AAAAA  KKGGA  HH  AGGG KKGG  RR G G  AA  GAAG GGGGGGGHHHG  KKAAAAAHHHHAAGGGG HHH  GKKGGGGGK GHHGAA  GGGG SAAATGTAGNNNNVGGTTAG GGGTAGGGG     G  GEE  KAAAGRRRGGGG AAA  Q  AA  GGMGKAA       G   GGG        AGKS  GKAA  GA A    GSASAGRRGAAGGGGGGAAAA  AGGLA   AAAA  L      GAG GGAG        R  A      GGGVVAAAA  EEEE AAG  GG       GAA    A            A RG AGGG   GNGGEG GG  EGG                  GGG   GGGGGNNNNNNNNNNNNNGG   AAAA         GGGGGGGGGS     AAAAAGGGGGG  GGG     GGGGG                              GGGGGG             GGGGGGGGGGGGGTAGGGGGGGGGGGGGAGGGGGGGGG      A LLLGGGGN      A      GG   P  GG       3B  E 
 L  DDDEEE  IIIEEELLDDAAA  LQQNNEEELLEEE        LL   DDII  LLLIIHHIIIIILEEEEEVVEEEDII   IIIII   LLLL   HHII    EEEILLLIII    RRR RRIINNIIIVV  DDDD  DDEEEVVLIIQQQDD   AARRNN            IIIEEKKK  QQMMEEEEEDDLLII  IIITT III  LLIIEEEEEEEEEEL   LLIII  DDLIT  EE  LLIL DDLL  RR L L  LL  LLLL HIIIIIIEEEL  DDTTLLLEEEEVVQIII EEE  LDDLIIIIS IEELTT  ILLL VLSSQQQAQKKKKLLQQQIQ LMLQILLLK     V  ILL  CLLLIDDDLLLL LLL  C  LL  QLQWTLL       W   LIW        ILCL  LSLL  LL V    VLRFLLDDKLLLLLLLSRLLI  LQQLL   LLLL  Q      LYQ LV L        M  L      LLVLLVVCC  LLLL TTQ  LL       LLL    L            L LL LEEQ   L MLQL LQ  V                               VVVVVVVVVVVVVII   DDDD         KKKK     L     LLLLLIIIKKK                                             YYYYYY             MMMMMMM      MDRRRMMMMLLLLFFATTTTTTTTT        KKK    G  LLLLL      KV   L  KQ      E0B  E 
 R  KKKTTT  RRRKKKRRKKKKK  LRRKKKKKRRRRR        RR   RRRR  IIIRRKKRRRRRYKKKKKRRKKKKRR   RRRRR   RRCC   KKRR    KKKRRRRRRR    KKK QQRRKKRRRAA  KKRR  KKKKKRRHRRLLLKK   RRVVKK            RRRKKLLL  RRQQRRRKKKKRRRR  HHHRR RRR  RRRRKKRRRRRRRRV   RRRRR  KKLRR  KK  ELRC KKRR  RR L R  KK  RKKY CRRRRRRKKKL  KKRRQQQKKKKPPRRRR KKK   KKCRRRRK RRRPKK  RLR  KEKKRKRQKLLLLPLKRRRK IKVRRLLLH     K  RII  FRRRSKKKLLLL RKK  F  KK  RKRRRRR       A   LRA        RRFL  LRQQ  LR S    RLRTLRRRKRVPLIHHRRRRR  LRRRL   RRRR  R      CKR PR R        W  L      RLRSSMMAA  VVKK RRR  SS       RRL    L            R CR LRRR   RRWFIR  R  L                               IIIIIIIIIIIII     VVVV         YYYY                   FFF                                             LLLLLL             LLLLLLL       RVVV    PPPPVVLYYYYFFFFF        CCC    S  VVVVL      LF   L  LI      E3   E 
 L  LLLLLL  LLLLLLLLLLLLL  LFFMMLLLLLLLL        LL   VVLL  LLLLLLLLLLLLMLLLLLLLLLLLLL   LLLLL   LLLL   LLLL    LLLLLLLLLL    LLL LLLLMMLLLLL  LLLL  LLLLLLLFLLLLLLL   LLLLLL            LLLLLLLL  LLLLLLLLLLLLLLL  LLLLL LLL  LLLLLLLLLLLLLLL   LLLLL  LLLLL  LL  LLLL LLLL  LL L L  MM  LMMM LLLLLLLLLLL  LLLLLLLLLLLLLLLLL LLL   LLLLLLLL LLLLLL  LLM  LLLLLLLLLMMMMHLLLLLL LLLLLFLLI     M  LNN  LLLLVLLLLLLL YMM  L  MM  FLLYLII       L   LCL        LLLL  LLLL  LC L    CFYSVLLLILIVLLLLLYLLV  ILLLV   LLLL  L      FIL ML L        L  V      LLLVVIILL  KKKK IIY  LL       FVV    V            L LL VLLL   LVLMLL  F  L                               LLLLLLLLLLLLL     LLLL         LLLL                   III                                             LLLLLL                           ILLL    LLLLIILKKKKIIIII        III    L  LLLLL      II   L  IV      E3B  EE
 L  LLLLLL  LLLLLLLLLLLLL  L  LLLLLLLLLL        LL   LLLL  LLLLLLLLLLLLLLLLLLLLLLLLLL   LLLLL   LLLL   LLLL    LLLLLLLLLL    LLL LLLLLLLLLLL  LLLL  LLLLLLLLLL   LL   LLLLLL            LLLLLLLL  LLLLLLLLLLLLLLL  LLLLL LLL  LLLLLLLLLLLLLLL   LLLLL  LLLLK  LL  LLLL LLLL  LL L L  LL  LLLL LLLLLLLLLLL  LLKKLLLLLLLLLLLLL LLL   LLLLLLLL LLLLKK  LLL  KLKKLLLMLLLLLLLLLLLL LLLLLLLLL     L  LLL  LLLLTLLLLLLL LLL  L  LL  LLLLLLL       F   LLF        LLLL  FLLL  LL L    LLLLLLLLLLLLLLLLKLLLL  LLLLL   LLLL  L      LLL LL L        L  L      LFLLLLLLL  LLLL LLL  LL       FLL    L            L LL LLLL   LLLLLL  L  L                               FFFFFFFFFFFFF     VVVV                                DDD                                             DDDDDD                                   IIIINN TTTTVVVVV        NNN    L  KKKK        I   L  IL      E5B  EE
 E  SSSRRR  EEESSSDDSSSSS  P  SSSSSDDAAA        DD   EEEE  EEEEESSEEEEEQSSSSSEESSSSEE   EEEEE   DDEE   SSEE    SSSEDDPEEE    QQQ EEEESSEEEEE  SSSS  SSSSSEEPEE   SS   EEEESS            EEESS     EE  AAASSSSDDEE  EEEEE EEE  EEEESSQQQQQQQQE   DDEEE  SSPEP      ESEP SSEE  EE T N  EE  SEEQ QEEEEEETTTT  SSPPEEESSSSEEEEEE SSS   SSPEEEES ESSPPP  ERE  PEPPNEN E    RQENNQE PQPNQ PPE     Q  EEE  PQQQEEEEPPPP EEE  P  EE  EENEEEE       P   PEP        EEPP  PE    EE      ESLPEPEEEEEPPPPPPEQQE  E   E   QQQQ  N      P   LP S        P  E      PPE  EE    EEEE EEE  EE       PEE    E            Q PP E  E   EEPPQE  E  P                               PPPPPPPPPPPPP     PPPP                                PPP                                             SSSSSS                                   EEEEPP PPPPPPPPP        KKK       PPPP        P   P          E3   EE
 A  AAAAAA  AAAAAAAAAAAAA  L  AAAAAAAAAA        AA     AA  AAAAAAAAAAAAVAAAAAAAAAAAAA   AAAAA   AAAA   AAAA    AAAAAALAAA        AAAAAAAAAAA  AAAA  AAAAAAALAA   AA   AAAAAA            AAAAA     AA  AAAAAAAAAAA  AAAAA AAA  AAAAAAAAAAAAAAA   AAAAA  AAVAA      AVAL AAAA     V A  AA  LAAL IAAAAAAAAAV  AAAAAAAAAAAAAAAAA AAA   AALAAAAA AAALAA  AAA  AAAAAAA A    V AAAAA LAIAA AAA     A  AKK  VAAALAAAI    AAA     AA   VAVA         I   A V        AAVA  VA    AA       LAAAVAAVASAAILLAAAA   A  AA   AAAA  A      L   AV V        V  A      LVA  SS    KKKK   V  AA       VSS    S            A VV A  A   ADVL A  V  L                                                 LLLL                                LLL                                             AAAAAA                                   SSSSYY LLLL             VVV    V  LLLL                        3B    
 A          QQQ   QQ       P       QQ           QQ     QQ  QQQQQ  QQQQQG     QQ    QQ   QQQQQ   QQQQ     QQ       QQQKQQQ        QQQQ  QQQQQ             QQ QQ        QQQQ              QQQ       QQ         QQQQ  QQQQQ QQQ  QQQQ          Q   QQQQQ    HQQ      QQQK   QQ     Q S  QQ  AQQA AQQQQQQ   P    QQQQQ    QQ QQQ         KQQQQ  Q  SQQ  QKS  QQQQQQQ Q    Q QQQQQ K HQQ AAQ        QAA  GQQQAAAAT    QQQ     QQ   SQI          T   T          QTG   A     SQ       KQ QRAAQQ  TLSSQQQQ   Q  AQ   QQQQ         S   SR K        R  Q      KS         AAAA   I  QQ       K                   Q KR Q  Q   SPRS Q  R  K                                                 AAAA                                                                                TTTTTT                                       AA KKKK             KKK    S  SSSS                        6     
 S                         S                               AAA         E                                             G           AA                                     AA                                                                  A            K K      AK E   II     K A      D  G E         E    KKAAA    EE             V         DKK  IDS  KAKKKAK A      AKKEA D DKE S          ISS  QEEEGAAAD                 EKP                          EE                  K   PAA    SDGGK QQ      G    QQQQ         K   SP P        P          S         SSSS   P           Q                   E RQ        SSPK    P  A                                                                                                                                     KKKKKK                                       SS GGGG             GGG    K  EEEE                        7     
 V                                                         AAA         R                                                         AA                                     AA                                                                  A            R A      AR K   AA     R K      R  R K         K    AAAAA    AA             H         EAA  AKF  AAAAAAA A      AAA A K KA             AKK  R   MVVVK                  AF                           R                  K   QVV     EMMA         F    AAAA         A   KQ Q        Q          A         KKKK   F           K                     RR        QDQP    F  Q                                                                                                                                     KKKKKK                                                           KKK    K  FFFF                        8     
 S                                                         TTT                                                                   TT                                     TT                                                                  T            G        TS     SS     S           G G                TTT    TT             E         A    SSS   T   T  T      T   T                  SGG      IGGG                    S                                                  EGG     S            S                 E   DE E        E          Y         GGGG   S                                           SDEQ                                                                                                                                                                                                                     S                              8     
 S                                                                                                                                                                                                                                                                       KK                 S S                                      V         I     TS                                                 TYYY                    D                                                   YY     K            D                     T  K        A          S         KKKK   D                                           ST S                                                                                                                                                                                                                     G                              9     
 K                                                                                                                                                                                                                                                                                                                                   K         K      K                                                 KKKK                                                                        KK     K                                                                                                                      KK                                                                                                                                                                                                                       K                              9     
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