Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 G 0 -2 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 2 H -2 -1 0 -2 -4 0 -1 -3 9 -4 -3 -2 -2 -1 -3 -2 -2 -2 4 -4 0 0 0 0 0 0 0 0 87 0 0 0 0 0 0 0 0 0 13 0 1.24 0.21 3 V -1 1 -1 -1 -4 1 2 -3 -2 -2 -2 5 -2 -4 -2 -1 -1 -4 -3 1 0 0 0 0 0 0 15 0 0 0 0 69 0 0 0 0 0 0 0 16 0.53 0.21 4 A 1 -1 -1 -2 -3 -1 -1 -3 8 -2 0 -2 -1 -2 -3 -1 -2 -3 1 -2 16 0 0 0 0 0 0 0 69 0 15 0 0 0 0 0 0 0 0 0 0.79 0.21 5 G 0 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.35 0.21 6 S -1 -1 -1 0 -3 1 5 -2 -1 -3 -3 0 -2 -4 -2 3 2 -4 -3 -3 0 0 0 0 0 0 54 0 0 0 0 0 0 0 0 30 15 0 0 0 0.58 0.21 7 M -2 -2 -3 -4 -2 -1 -3 -4 -2 1 2 -2 8 -1 -3 -2 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.85 0.21 8 D -3 -2 1 7 -5 -1 1 -2 -2 -4 -5 -1 -4 -5 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.29 0.21 9 I -2 -4 -3 -4 -2 -3 -4 -4 -4 5 1 -3 0 -1 -3 -2 1 -4 -2 3 0 0 0 0 0 0 0 0 0 71 0 0 0 0 0 0 14 0 0 15 0.55 0.21 10 T -1 2 -1 -2 -2 -1 -1 -2 -2 -2 -2 2 -2 -3 -2 2 5 -4 -2 -1 0 14 0 0 0 0 0 0 0 0 0 14 0 0 0 15 57 0 0 0 0.49 0.21 11 Q 1 2 -2 -2 -2 2 -1 -2 -2 0 -1 -1 -1 -3 -2 1 -1 -4 -2 3 14 15 0 0 0 16 0 0 0 0 0 0 0 0 0 15 0 0 0 40 0.24 0.21 12 Q -2 0 -1 -1 -4 7 1 -3 4 -4 -3 1 -1 -4 -2 -1 -2 -3 -1 -3 0 0 0 0 0 86 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0.91 0.21 13 E -2 0 -1 1 -4 4 6 -3 -1 -4 -4 0 -2 -4 -2 -1 -2 -3 -3 -3 0 0 0 0 0 29 71 0 0 0 0 0 0 0 0 0 0 0 0 0 0.88 0.21 14 K 1 0 -1 -1 -3 4 2 -2 4 -4 -3 3 -2 -4 -2 -1 -1 -3 -2 -3 14 0 0 0 0 28 14 0 15 0 0 29 0 0 0 0 0 0 0 0 0.48 0.21 15 T 1 -2 -1 -2 -2 -1 -2 -2 -2 -2 -2 -1 -1 -3 -2 1 6 -3 -2 -1 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85 0 0 0 0.68 0.21 16 F -3 -4 -4 -5 -3 -4 -4 -4 -2 -1 0 -4 -1 8 -5 -3 -3 0 3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.19 0.21 17 A 2 -2 2 4 -3 -1 2 -2 -2 -2 -3 -1 -2 -3 -2 0 -1 -4 -3 1 30 0 14 27 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 15 0.34 0.21 18 G 1 -2 -1 -2 -3 2 -2 5 -2 -3 -4 -1 -2 -4 -2 0 1 -3 -3 -3 13 0 0 0 0 13 0 59 0 0 0 0 0 0 0 0 15 0 0 0 0.67 0.21 19 F -3 -4 -4 -5 -3 -4 -4 -4 -2 -1 0 -4 -1 8 -5 -3 -3 0 3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.19 0.21 20 V -2 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 4 -1 -4 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 69 0 0 15 0 0 0 0 0 0 16 0.61 0.21 21 R -1 5 -1 -2 -4 0 0 -2 -1 -4 -3 4 -2 -4 -2 1 -1 -4 -3 -3 0 46 0 0 0 0 0 0 0 0 0 40 0 0 0 14 0 0 0 0 0.68 0.21 22 M 0 -3 -4 -4 -3 -3 -3 -3 -3 -2 -1 -3 3 4 -4 -2 -2 10 1 -2 14 0 0 0 0 0 0 0 0 0 0 0 16 28 0 0 0 42 0 0 1.11 0.21 23 V 1 -2 -2 -2 -1 -2 -2 -2 -3 0 -1 -2 -1 -2 -2 2 2 -4 -2 3 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 14 0 0 44 0.32 0.21 24 T -1 -2 -2 -3 -2 -2 -2 -3 -3 2 0 -2 3 -2 -2 0 5 -3 -2 2 0 0 0 0 0 0 0 0 0 15 0 0 13 0 0 0 58 0 0 14 0.45 0.21 25 W -2 5 -2 -3 -4 0 -1 -3 -2 -4 -3 2 -2 -2 -3 -2 -2 8 -1 -3 0 56 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 30 0 0 1.04 0.21 26 A 1 -3 -3 -4 -2 -3 -3 1 -3 3 0 -3 3 -2 -3 -2 -1 -3 -2 3 16 0 0 0 0 0 0 13 0 29 0 0 15 0 0 0 0 0 0 27 0.31 0.21 27 A 2 -3 -1 -2 7 -2 -2 2 -3 -3 -3 -2 -2 -3 -2 3 2 -3 -3 -2 16 0 0 0 29 0 0 13 0 0 0 0 0 0 0 29 13 0 0 0 0.53 0.21 28 V -2 -4 -4 -4 5 -3 -4 -4 -4 4 2 -3 0 -1 -4 -3 -1 -3 -2 3 0 0 0 0 15 0 0 0 0 41 14 0 0 0 0 0 0 0 0 30 0.53 0.21 29 V -2 -3 -4 -4 -2 -3 -4 -5 -4 3 4 -3 1 3 -4 -3 -2 -2 -1 2 0 0 0 0 0 0 0 0 0 15 56 0 0 13 0 0 0 0 0 16 0.52 0.21 30 I 0 -2 -1 -2 -2 -2 -2 -2 -3 3 -1 -2 -1 -2 -2 4 0 -4 -2 2 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 56 0 0 0 15 0.35 0.21 31 V 1 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 0 -1 -3 -2 -1 -4 -2 3 15 0 0 0 0 0 0 0 0 69 0 0 0 0 0 0 0 0 0 16 0.52 0.21 32 A 3 -3 -2 -3 -2 -2 -2 3 -3 -1 -2 -2 -1 -3 -2 0 -1 -4 -3 2 44 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 0 28 0.42 0.21 33 A 1 -3 -3 -3 -2 -3 -3 -3 -3 3 0 -3 0 -2 -3 1 -1 -4 -2 4 16 0 0 0 0 0 0 0 0 29 0 0 0 0 0 13 0 0 0 43 0.36 0.21 34 L -2 -3 -4 -5 -2 -3 -4 -5 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.76 0.21 35 I -2 -4 -4 -4 -2 -3 -4 -5 -4 5 1 -3 0 -1 -4 -3 -1 -4 -2 4 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 41 0.63 0.21 36 F -3 -4 -4 -5 -3 -4 -4 -4 -2 0 1 -4 0 7 -5 -3 -3 0 2 -1 0 0 0 0 0 0 0 0 0 0 13 0 0 87 0 0 0 0 0 0 1.02 0.21 37 L -2 -2 -4 -4 -2 -2 -3 -4 -3 1 4 -3 7 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 42 0 58 0 0 0 0 0 0 0 0.67 0.21 38 A 5 -2 -2 -3 -1 -2 -2 0 -2 -2 -2 -1 -2 -3 -2 1 -1 -3 -3 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.71 0.21 39 L -2 -3 -4 -5 -2 -3 -4 -5 -4 3 5 -3 1 0 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 28 72 0 0 0 0 0 0 0 0 0 0.64 0.21 40 A 1 -3 -3 -3 -2 -3 -3 -3 -3 1 -1 -3 -1 4 -3 1 -1 -2 0 3 16 0 0 0 0 0 0 0 0 0 0 0 0 28 0 14 0 0 0 42 0.33 0.21 41 N -2 -1 7 1 -4 -1 -1 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.12 0.21 42 A 3 -2 -1 -2 -2 -2 -2 4 -2 -3 -3 -2 -3 -4 -2 3 -1 -4 -3 -2 30 0 0 0 0 0 0 41 0 0 0 0 0 0 0 29 0 0 0 0 0.60 0.21 K Lambda Standard Ungapped 0.1335 0.3293 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1696 0.3181 PSI Gapped 0.0519 0.2670