Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 2 0 -3 -2 -1 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0.52 0.13 2 S 1 -1 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -4 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.73 0.20 3 R -2 5 -1 -2 -3 0 -1 -3 -1 -3 -3 3 -2 -4 -2 -1 2 -4 -2 -2 0 54 0 0 0 0 0 0 0 0 0 22 0 0 0 0 24 0 0 0 0.64 0.20 4 S 2 -2 0 -1 -1 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -4 -2 -2 22 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 0 0 0 0 0.60 0.20 5 V -1 -3 -3 -3 -1 -3 -3 -4 -4 2 0 -3 0 -2 -3 -1 3 -4 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 76 0.50 0.20 6 I -2 -4 -4 -4 -2 -3 -4 -5 -4 5 3 -3 1 -1 -4 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 77 23 0 0 0 0 0 0 0 0 0 0.64 0.20 7 R 1 6 -1 -2 -3 0 -1 -2 -1 -3 -3 2 -2 -4 -2 -1 -1 -4 -2 -3 22 66 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0.69 0.20 8 S 1 -1 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -4 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.73 0.20 9 I -2 -3 -4 -4 -2 -3 -4 -5 -4 5 3 -3 3 -1 -4 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 66 22 0 12 0 0 0 0 0 0 0 0.58 0.20 10 I -2 -4 -4 -4 -2 -4 -4 -5 -4 6 1 -4 1 -1 -4 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.74 0.20 11 K -2 5 -1 -2 -4 1 0 -3 -1 -4 -3 5 -2 -4 -2 -1 -2 -4 -3 -3 0 46 0 0 0 0 0 0 0 0 0 54 0 0 0 0 0 0 0 0 0.79 0.20 12 S 1 -1 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -4 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.73 0.20 13 S 1 -1 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -4 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.73 0.20 14 R -2 4 4 -1 -4 0 -1 -2 4 -4 -4 3 -2 -3 -3 -1 -1 -4 -2 -4 0 26 36 0 0 0 0 0 17 0 0 21 0 0 0 0 0 0 0 0 0.60 0.20 15 L -2 -3 -4 -4 -2 -3 -4 -4 -4 2 4 -3 1 0 -4 -3 -2 -3 -2 2 0 0 0 0 0 0 0 0 0 9 69 0 0 0 0 0 0 0 0 22 0.57 0.20 16 E -2 -2 2 5 -4 0 3 2 -1 -4 -4 -1 -3 -4 -2 -1 -2 -4 -3 -4 0 0 10 46 0 0 27 17 0 0 0 0 0 0 0 0 0 0 0 0 0.70 0.20 17 E -1 0 -1 0 -3 5 4 -3 -1 0 -2 0 -1 -3 -2 1 -1 -3 -2 -2 0 0 0 0 0 46 32 0 0 10 0 0 0 0 0 12 0 0 0 0 0.55 0.20 18 D -1 -2 1 6 -4 0 2 -2 -2 -4 -4 -1 -3 -4 -2 2 -1 -5 -3 -4 0 0 0 66 0 0 12 0 0 0 0 0 0 0 0 22 0 0 0 0 0.83 0.20 19 R -2 4 -1 -2 -3 0 -1 -3 7 -2 1 0 -1 -2 -3 -2 -2 -3 0 -2 0 32 0 0 0 0 0 0 44 0 24 0 0 0 0 0 0 0 0 0 0.60 0.20 20 K -1 2 -1 -1 -4 1 0 -2 -1 -4 -3 6 -2 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.84 0.20 21 R -2 3 2 2 -3 2 0 -2 3 -3 -3 0 -2 -3 -2 0 2 -4 -2 -3 0 27 9 18 0 11 0 0 11 0 0 0 0 0 0 0 24 0 0 0 0.41 0.20 22 Y -2 -1 3 -1 -3 -1 -1 -2 0 -3 -3 2 -2 0 -3 1 -1 0 6 -3 0 0 22 0 0 0 0 0 0 0 0 24 0 0 0 12 0 0 42 0 0.49 0.20 23 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 5 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 66 0 34 0 0 0 0 0 0 0 0.64 0.20 24 M -2 -3 -4 -4 -2 -2 -3 -4 -3 2 4 -3 5 0 -4 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 12 56 0 32 0 0 0 0 0 0 0 0.59 0.20 25 T 1 -2 -1 1 -2 -1 -1 2 -2 -2 -3 -1 -2 -3 -2 2 4 -4 -3 -2 11 0 0 10 0 0 0 21 0 0 0 0 0 0 0 19 39 0 0 0 0.41 0.20 26 L -2 -3 -4 -4 -2 -3 -4 -5 -4 3 5 -3 1 0 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 24 76 0 0 0 0 0 0 0 0 0 0.64 0.20 27 L -2 -3 -4 -5 -2 -3 -4 -5 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.75 0.20 28 D -1 0 5 3 -3 0 0 -1 -1 -4 -4 2 -3 -4 -2 2 0 -4 -3 -3 0 0 39 15 0 0 0 0 0 0 0 22 0 0 0 24 0 0 0 0 0.54 0.20 29 D -2 -1 4 5 -4 3 1 -2 -1 -4 -4 -1 -3 -4 -2 -1 -1 -4 -3 -4 0 0 22 54 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.79 0.20 30 I -2 -4 -4 -4 -2 -3 -4 -5 -4 5 1 -3 1 -1 -4 -3 -1 -4 -2 3 0 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 0 0 0 22 0.66 0.20 31 K -2 4 -1 -1 -4 3 0 -3 -1 -4 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 24 0 0 0 17 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0.70 0.20 32 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 1 -2 -3 -4 -4 0 0 0 0 0 0 0 88 0 0 0 0 0 0 0 12 0 0 0 0 1.13 0.20 33 A 2 -2 0 3 -2 -1 -1 2 -2 -3 -3 -1 -2 -3 -2 3 2 -4 -3 -2 26 0 0 22 0 0 0 12 0 0 0 0 0 0 0 27 13 0 0 0 0.38 0.20 34 N -2 0 3 4 -4 0 2 -2 -1 -4 -4 4 -3 -4 -2 -1 -1 -4 -3 -4 0 0 15 33 0 0 13 0 0 0 0 39 0 0 0 0 0 0 0 0 0.60 0.20 35 D -2 -2 5 6 -4 -1 0 -2 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 46 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.94 0.20 36 L -2 -3 -4 -4 -2 -3 -4 -5 -4 2 5 -3 1 0 -4 -3 -2 -3 -2 2 0 0 0 0 0 0 0 0 0 11 76 0 0 0 0 0 0 0 0 13 0.61 0.20 37 A 2 2 3 -1 -3 0 -1 1 -1 -3 -3 2 -2 -4 -2 0 -1 -4 -3 -2 32 11 22 0 0 0 0 12 0 0 0 23 0 0 0 0 0 0 0 0 0.36 0.20 38 K -2 0 -1 1 -4 3 5 -3 -1 -4 -4 2 -2 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 17 68 0 0 0 0 15 0 0 0 0 0 0 0 0 0.79 0.20 39 F -3 -4 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 -1 8 -5 -3 -3 0 3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.17 0.20 40 H -2 -2 -1 -3 -4 -1 -2 -3 7 -3 -2 -2 -2 1 -3 -2 -2 1 7 -3 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 0 0 0 58 0 1.03 0.20 41 Q -1 0 -1 0 -4 6 3 -3 0 -4 -3 2 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 66 24 0 0 0 0 10 0 0 0 0 0 0 0 0 0.79 0.20 42 M -2 -1 -2 -3 -2 0 -2 -3 -2 0 1 2 7 -1 -3 -2 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 24 76 0 0 0 0 0 0 0 0.58 0.20 43 L -1 -3 -4 -4 -2 -3 -4 -4 -4 3 3 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 11 42 0 0 0 0 0 0 0 0 47 0.52 0.20 44 V 0 0 -2 -3 -2 -1 -1 -3 -2 0 0 3 5 -2 -2 -1 1 -3 -2 1 9 0 0 0 0 0 0 0 0 0 0 34 31 0 0 0 10 0 0 15 0.28 0.20 45 K 1 0 -1 -2 -2 0 -1 -2 -2 2 -1 4 -1 -3 -2 2 -1 -4 -2 -1 10 0 0 0 0 0 0 0 0 24 0 44 0 0 0 22 0 0 0 0 0.29 0.20 46 I -2 -4 -4 -4 -2 -3 -4 -5 -4 5 3 -3 1 -1 -4 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 76 24 0 0 0 0 0 0 0 0 0 0.63 0.20 47 I -2 -4 -4 -4 -2 -3 -4 -5 -4 5 3 -3 1 0 -4 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 77 23 0 0 0 0 0 0 0 0 0 0.58 0.16 48 M 2 -2 -2 -3 -1 -1 -2 -1 -2 0 1 -1 5 -1 -2 0 -1 -2 -2 0 39 0 0 0 0 0 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0.26 0.05 49 K -1 2 0 -1 -4 1 1 -2 -1 -3 -3 5 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.59 0.05 50 H -1 0 0 -1 -3 4 1 -2 7 -3 -3 0 -1 -2 -2 -1 -1 -3 0 -3 0 0 0 0 0 50 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0.64 0.04 51 H -2 0 1 -1 -3 0 0 -2 8 -3 -3 -1 -2 -1 -2 -1 -2 -2 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 52 H -2 0 1 -1 -3 0 0 -2 8 -3 -3 -1 -2 -1 -2 -1 -2 -2 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 53 H -2 0 1 -1 -3 0 0 -2 8 -3 -3 -1 -2 -1 -2 -1 -2 -2 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 K Lambda Standard Ungapped 0.1358 0.3258 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1652 0.3177 PSI Gapped 0.0506 0.2670