Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 P -4 -6 -6 -5 -6 -5 -5 -6 -6 -6 -7 -4 -6 -7 9 -4 -5 -7 -7 -6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 3.17 1.78 2 L -1 1 -4 -5 1 -3 -3 -5 -5 3 3 -1 0 2 -1 -3 -1 -4 -2 1 5 8 1 1 2 1 2 1 0 18 28 3 1 7 4 2 3 0 1 10 0.40 1.92 3 P -2 2 -4 -4 -4 -2 -1 -1 -2 -5 -3 4 -4 -6 6 -1 -2 -7 -4 -4 3 10 0 1 0 2 3 4 1 0 4 26 0 0 38 4 2 0 0 1 1.02 1.98 4 N -2 0 3 1 -4 -1 0 3 -1 -4 -5 0 -3 -4 -1 2 3 -6 -4 -3 2 4 14 9 0 2 5 19 1 1 1 5 1 1 4 14 15 0 0 2 0.45 2.01 5 Q -1 2 -2 -3 -4 4 -3 1 -1 -4 -4 3 -3 -6 3 2 -1 -5 -5 -3 4 11 2 1 0 17 1 11 1 1 2 16 1 0 14 13 3 0 0 1 0.54 2.06 6 Q -3 -4 -5 -5 -2 1 -5 -6 -2 3 2 -5 2 -3 -5 -3 0 -4 -2 5 2 1 0 1 1 7 0 0 1 14 20 0 5 1 0 1 6 0 1 38 0.79 2.09 7 F -6 -5 -6 -5 -3 -5 -6 -7 -5 -3 -3 -6 -2 9 -6 -5 -5 -2 2 -4 0 1 0 1 1 0 0 0 0 1 1 0 1 88 0 0 0 0 5 1 2.48 2.09 8 G -3 -3 -2 -3 -2 -5 -5 7 -4 -7 -7 -4 -6 -6 -5 -2 -4 -6 -5 -6 1 1 2 1 1 0 1 88 0 0 0 1 0 0 0 2 1 0 0 0 2.04 2.12 9 V 0 -1 -2 -5 3 1 -3 -3 -3 1 -2 -2 -1 -4 -6 0 0 -6 -3 5 7 4 2 0 6 6 2 2 1 6 4 2 1 1 0 7 5 0 1 43 0.62 2.14 10 S -2 -1 -2 3 -2 -2 0 -4 -2 -6 -5 -2 -4 -6 6 3 -1 -7 -5 -5 3 4 2 14 1 1 5 1 1 0 1 3 0 0 35 24 4 0 0 0 0.95 2.14 11 L -3 -5 -6 -7 -4 -5 -6 -5 -5 2 6 -5 0 0 -2 -5 -3 -5 -4 -1 2 0 0 0 0 0 0 1 0 9 75 0 1 4 3 0 2 0 0 2 1.34 2.15 12 Q 0 -1 0 2 -3 2 4 -3 0 -4 -3 -1 -3 -5 -1 1 1 -4 -3 -3 7 3 4 9 1 8 29 2 2 1 3 4 1 0 3 11 9 0 1 2 0.45 2.08 13 H 0 -1 -1 3 -2 0 3 -4 2 -1 -2 -1 -2 -2 -4 1 1 -5 0 0 8 3 3 13 1 5 20 1 5 3 3 4 1 2 1 9 8 0 3 7 0.29 2.05 14 L 0 -4 -4 -5 0 -2 -4 -5 0 3 4 -4 2 -2 -5 -2 -1 -2 -1 2 7 1 1 1 2 2 1 1 3 13 40 1 4 2 1 3 4 0 2 12 0.59 2.03 15 Q -1 -2 -3 -4 5 1 -2 -4 -1 1 1 -1 3 -1 0 -1 0 -2 -2 3 4 2 1 1 12 8 3 1 1 7 13 4 7 2 5 5 5 1 2 17 0.35 2.03 16 E -1 2 0 1 -1 3 4 -3 2 -4 -3 1 -2 -4 0 0 -2 -1 -3 -4 5 9 4 8 1 12 23 2 4 1 3 8 1 1 4 8 2 1 1 1 0.38 2.02 17 K 0 4 1 -1 -2 1 -1 -3 1 -2 -1 2 -1 -1 -3 0 -2 -3 1 -1 8 22 7 3 1 7 4 2 3 2 5 11 2 3 1 8 3 0 4 4 0.30 1.98 18 N -2 0 2 3 0 3 1 0 1 -3 -4 -1 -2 -1 -2 1 1 -3 -1 -3 3 4 9 14 2 12 8 8 3 1 2 3 1 3 2 10 7 0 2 2 0.27 1.88 19 P -1 2 1 -1 -2 2 -2 1 1 -2 -1 1 -1 -2 2 0 -1 -2 0 -2 6 9 7 3 1 8 3 11 3 3 7 7 2 2 11 7 4 1 3 2 0.13 1.84 20 E -2 0 0 2 1 -1 3 -1 -2 -2 -2 0 -1 -3 1 1 1 0 -2 -2 3 5 4 12 3 3 19 5 1 3 4 6 2 1 6 9 9 1 2 3 0.23 1.93 21 Q -1 1 1 0 -2 1 1 3 1 -3 -3 2 -3 -3 1 0 -1 -3 -1 -3 4 7 7 5 1 5 9 19 3 1 3 12 1 1 6 6 4 0 3 2 0.24 1.97 22 E -2 1 1 2 0 1 0 0 1 -2 -1 0 -2 1 -1 1 0 -2 1 -1 3 8 6 9 2 6 6 6 3 3 7 6 1 5 3 9 5 1 5 5 0.08 1.93 23 P -1 1 0 0 -2 0 0 0 0 -3 -1 0 1 -2 4 -1 0 1 -1 -2 5 7 4 6 1 5 5 7 2 2 7 5 3 2 19 5 7 2 2 3 0.21 1.90 24 I -2 -5 -5 -6 -3 -4 -5 -5 -4 5 2 -5 0 -2 -3 -4 -2 -6 -2 5 2 1 1 0 1 1 1 1 1 31 19 1 2 1 2 1 2 0 1 34 0.97 2.04 25 P -2 -5 -4 -4 -6 -4 -4 -6 -3 -5 -5 -5 -4 -7 9 -3 -3 -2 -4 -5 3 0 1 1 0 1 1 0 1 1 1 0 1 0 86 1 1 1 1 1 2.54 2.08 26 I 0 1 -2 -2 -2 0 -2 -3 -1 1 1 1 1 0 0 0 0 2 0 0 9 7 2 3 1 5 3 2 1 9 15 8 3 4 6 6 5 3 3 6 0.11 2.10 27 V -2 -4 -4 -5 -1 -4 -2 -4 -4 5 1 -4 -1 4 1 -2 -3 -3 -2 4 2 1 1 1 1 1 3 1 0 25 12 1 1 13 6 3 1 0 1 24 0.65 2.09 28 L -4 -4 -4 -5 -1 -3 -5 -6 -6 4 3 -4 2 1 -3 -4 -4 -2 -3 5 1 1 1 1 1 2 1 0 0 19 28 1 4 5 1 1 1 1 1 33 0.86 2.09 29 R -2 2 -1 1 -2 2 2 -4 1 -1 0 1 0 -2 -3 -2 0 3 1 0 4 10 4 7 1 9 14 1 3 3 8 7 2 2 1 3 7 4 5 8 0.19 2.11 30 E -1 2 -1 2 -1 2 1 -4 0 -2 -1 3 2 -2 -4 -1 -1 -1 -2 -2 4 11 3 10 1 10 8 1 2 3 5 18 5 1 1 5 4 1 1 3 0.30 2.10 31 T 0 -4 -6 -6 9 -3 -6 -4 -3 2 2 -4 3 -2 -4 -2 -1 -5 -3 -1 9 1 0 0 38 1 0 1 1 9 17 1 7 2 1 3 4 0 1 3 1.15 2.10 32 V -2 -3 -4 -4 4 -2 -4 -3 -2 5 2 -4 1 1 -4 -3 -1 -2 -3 3 4 1 1 1 7 2 1 3 1 29 15 1 4 5 1 2 4 1 1 17 0.60 2.15 33 A -1 1 0 2 0 2 2 -3 0 -3 -2 0 1 -3 -3 1 1 -1 -2 -2 6 8 5 12 2 9 13 2 3 2 4 6 3 1 1 10 7 1 2 2 0.19 2.15 34 Y 0 -2 -2 -3 1 -1 1 -4 3 -1 -2 -2 0 4 -6 -2 -2 1 6 -1 9 3 2 2 3 3 8 1 6 3 3 2 2 16 0 3 2 2 22 4 0.53 2.12 35 L -3 -3 -3 -6 -1 -3 -4 -7 -6 4 5 -3 2 -1 -3 -5 -3 -5 -2 1 1 1 1 0 1 1 1 0 0 24 43 1 4 3 1 0 1 0 1 10 0.85 2.12 36 Q -2 2 1 1 -1 0 4 -3 0 -2 -1 0 -1 -2 -3 -1 -1 0 1 -3 3 10 5 7 2 3 28 2 2 2 6 6 2 2 1 5 5 1 5 2 0.34 2.21 37 A 0 1 1 -1 0 3 2 -2 1 -2 -1 2 0 -2 -2 0 0 1 -1 -2 7 7 5 3 2 12 12 3 3 3 5 11 3 2 2 8 5 2 3 3 0.18 2.19 38 H -2 2 2 0 2 0 0 -2 4 -2 -3 1 2 -1 -1 -1 0 2 1 -2 3 10 9 5 5 5 7 4 9 3 3 9 5 3 3 4 6 3 4 3 0.21 2.21 39 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 40 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 41 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 42 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 43 E -3 -1 -1 2 -1 1 5 -4 -1 -3 -3 1 -1 -3 2 -2 -2 -5 -1 0 2 2 3 9 1 7 32 1 1 1 2 7 2 1 8 3 3 0 3 7 0.44 2.04 44 G -2 -1 0 0 0 -1 -2 5 2 -3 -3 -2 -2 -1 -3 0 -3 0 -1 -3 2 3 5 6 2 3 3 43 4 1 3 3 1 3 1 6 2 1 2 2 0.55 2.01 45 I -2 -2 -2 -6 1 -5 -5 -2 0 4 3 -2 0 -1 -1 -3 -2 -5 -1 1 3 3 2 0 2 0 0 3 2 25 31 3 2 3 3 2 2 0 2 7 0.51 1.97 46 F -2 -2 -5 -1 1 -1 -5 -2 1 -1 -2 -2 1 6 -2 -2 -2 4 4 -2 3 3 0 4 3 3 0 4 4 3 4 3 4 29 3 4 3 6 13 3 0.60 2.07 47 R -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 48 R -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 49 S -1 -1 0 -1 3 -1 0 -2 1 -2 -2 -1 0 -1 2 3 -1 2 0 -2 6 3 5 3 5 3 7 4 3 3 4 3 2 3 11 19 4 2 3 3 0.15 2.19 50 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 51 N -1 0 3 1 1 0 -1 -1 1 -1 -2 -1 0 -1 -1 3 -1 -6 -1 0 5 4 13 8 3 4 4 4 3 3 5 4 3 3 3 18 4 0 3 6 0.18 2.07 52 T -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 53 Q 0 0 1 0 1 0 -1 -1 1 -1 -2 1 0 -1 -1 2 0 2 -1 -1 8 5 5 5 2 4 5 5 3 3 5 9 3 3 4 13 6 2 3 5 0.03 2.15 54 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 55 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 56 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 57 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 58 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 59 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 60 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 61 K -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 62 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 63 N -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 64 M -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 65 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 66 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 67 P -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 68 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 69 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 70 F -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 71 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 72 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 73 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 74 N -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 75 A -1 -1 0 3 2 0 0 -2 1 -1 -2 -1 0 -1 1 0 0 3 0 -1 5 3 5 15 4 4 6 3 4 4 4 3 3 3 6 8 5 4 3 4 0.10 2.24 76 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 77 H -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 78 L -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 79 P 0 -2 -1 -5 2 -1 -1 -2 1 2 0 -2 1 0 1 -2 -1 2 0 3 7 3 3 0 4 3 4 3 3 13 8 3 3 3 8 3 3 2 3 17 0.15 2.07 80 A -1 0 0 0 3 1 0 -1 2 0 -1 0 2 1 0 -1 0 -5 -4 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 0 5 0.03 2.01 81 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 82 I -1 -4 0 0 3 1 0 -1 -4 0 -1 0 2 1 0 -1 0 4 1 -1 5 0 5 5 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 0.07 2.01 83 L -1 0 -4 0 3 1 0 -5 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 0 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 0.11 2.01 84 K -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 85 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 86 F -1 0 0 -5 3 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.07 2.12 87 L -1 -4 -4 0 3 1 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 0 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.10 2.01 88 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 89 E -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 90 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 91 P -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 92 E -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 93 P -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 94 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 95 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 96 T -1 -1 0 -1 1 0 0 -1 2 -1 -2 -1 1 -1 2 0 3 2 1 -1 4 3 4 4 3 4 6 4 4 3 5 3 4 3 11 6 15 3 4 4 0.11 2.21 97 F -1 -1 0 0 1 -1 0 -2 1 -1 -2 -1 0 2 0 1 -1 2 2 -2 6 4 5 6 3 3 7 3 4 3 5 4 2 9 5 9 4 3 8 3 0.07 2.23 98 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 99 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 100 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 101 P -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 102 H 0 1 0 0 1 1 1 -2 1 -1 -1 0 1 0 -1 -1 -1 2 1 -2 10 6 4 6 3 6 10 3 3 4 6 5 3 4 3 5 4 2 4 3 0.03 2.25 103 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 104 V -1 -1 -1 -1 2 0 -1 -3 1 2 1 -1 3 0 -1 -1 0 2 0 1 4 3 3 4 3 5 4 3 3 10 11 4 6 3 3 4 5 3 3 11 0.07 2.23 105 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 106 F -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 107 L 0 0 0 -1 3 1 -1 -2 1 0 0 -1 1 0 -1 -1 0 2 1 -1 9 5 4 4 5 7 4 3 3 5 8 4 4 3 3 5 5 3 5 5 0.02 2.23 108 N -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 109 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 110 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 111 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 112 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 113 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 114 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 115 V -1 0 -1 -1 1 0 -1 -2 1 2 1 -1 1 0 -1 -1 -1 2 0 1 5 4 3 3 3 4 4 3 3 10 15 4 4 4 3 4 4 2 4 10 0.05 2.23 116 P -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 117 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 118 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 119 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 120 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 121 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 122 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 123 Q -1 1 1 0 2 1 0 -2 2 -2 -1 1 1 -1 -1 0 -1 2 0 -2 5 6 6 6 4 6 7 4 4 3 7 7 3 3 4 8 4 3 3 3 0.03 2.23 124 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 125 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 126 P -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 127 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 128 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 129 N -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 130 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 131 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 132 V -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 133 L -1 0 0 0 3 0 -1 -1 2 0 -1 -4 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 0 5 5 5 5 5 5 5 5 0.07 2.12 134 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 135 F -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 136 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 137 T -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 138 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 139 F -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 140 L -1 -5 0 0 3 -4 0 -1 2 0 -1 -4 2 1 0 -1 0 4 1 0 6 0 5 6 5 0 6 6 5 6 6 0 5 5 6 6 6 5 5 6 0.13 1.89 141 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 142 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 143 I -1 0 0 0 3 0 0 -1 -4 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 144 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 145 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 146 H -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 147 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 148 D -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 149 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 150 N -1 0 1 0 3 1 0 -1 2 -4 -1 0 2 -4 0 0 0 -5 1 -1 6 6 5 6 5 5 6 6 5 0 6 6 5 0 6 6 6 0 5 6 0.07 1.89 151 K -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 152 M -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 153 T 0 -1 1 2 1 -1 -1 -1 2 -2 -2 -2 0 0 0 1 1 -5 3 -2 7 3 7 10 3 3 4 4 4 3 3 3 2 3 5 12 9 0 9 3 0.14 2.13 154 N 2 -2 -1 -3 0 -2 -2 -3 -1 1 0 -2 0 -1 2 1 1 1 0 1 16 2 3 2 2 2 3 2 2 9 8 2 2 3 11 8 7 2 3 11 0.18 2.14 155 T -1 2 1 0 -1 2 0 -2 3 -3 -3 1 -1 -2 -2 1 0 1 0 -3 6 11 6 5 1 9 7 4 7 2 2 9 2 2 2 11 7 2 3 2 0.20 2.12 156 N 0 -1 7 -1 -1 -1 -2 -2 0 -2 -4 -1 -1 -3 -3 0 0 -6 -2 -3 8 3 48 2 2 2 2 2 2 3 2 3 2 1 2 7 5 0 1 2 0.85 2.10 157 L -3 -5 -4 -6 -1 -3 -6 -6 -2 2 6 -4 1 -1 -4 -4 -3 -5 -2 1 2 0 1 0 1 1 0 0 1 10 63 1 2 2 1 1 1 0 1 9 1.03 2.04 158 A 5 -3 -3 -3 1 -3 -4 1 -5 -2 -3 -4 -2 -3 -3 2 -1 -6 -3 -1 53 1 1 1 2 1 0 11 0 2 2 0 1 1 1 14 3 0 1 4 0.85 2.00 159 V -1 -1 -2 -4 -1 -1 -2 -3 -1 4 0 0 3 -3 -3 0 2 -2 -3 2 5 3 2 1 1 3 2 2 2 25 6 5 6 1 1 6 14 1 1 13 0.37 2.02 160 V -1 -3 -4 -6 6 -2 -3 -4 -3 3 0 -4 0 -2 -4 -1 -1 -6 -3 5 4 1 1 0 14 2 2 1 1 17 6 1 2 1 1 4 3 0 1 37 0.82 2.01 161 F -4 -6 -6 -5 -2 -5 -4 -4 -5 1 1 -6 3 8 -6 -4 -3 4 -1 -1 1 0 0 1 1 0 1 1 0 9 14 0 7 52 0 1 1 4 1 4 1.33 1.96 162 G 3 -4 -3 -5 2 -1 -4 5 -2 -4 -4 -4 -2 -4 -3 1 0 -1 -3 -2 27 1 1 0 4 4 1 35 1 1 1 0 1 1 1 11 6 1 1 3 0.72 1.93 163 P -3 -2 -3 -3 -2 -3 -3 -4 0 -4 -3 -3 -2 -3 8 -1 -3 -6 -3 -4 2 3 1 2 1 1 1 2 2 1 3 1 1 1 71 4 1 0 1 1 1.81 1.94 164 N -1 -4 4 -3 5 -3 -4 -2 -1 0 0 -3 -2 -2 -4 2 3 -6 -2 0 4 1 18 1 10 1 0 3 2 6 8 1 1 2 1 14 20 0 2 7 0.50 1.95 165 L -4 -5 -4 -6 -1 -5 -6 -4 -6 4 5 -5 2 1 -6 -4 -4 0 -3 1 1 0 1 0 1 0 0 2 0 21 51 0 5 6 0 1 1 1 1 6 1.00 1.91 166 L -3 -3 -3 -5 -1 -3 -5 -5 -4 2 4 -4 4 4 -5 -4 -2 -4 -2 0 2 2 1 1 1 1 1 1 0 8 43 1 8 17 0 1 2 0 1 7 0.80 1.90 167 W -3 6 -1 -4 2 1 -3 -2 2 -3 -3 0 0 -1 0 0 -2 6 -1 -3 2 35 2 1 4 5 1 4 4 2 3 4 3 3 4 7 2 9 2 1 0.65 1.90 168 A -1 -2 -1 0 3 -1 -2 -2 2 -2 -3 -2 0 -3 5 2 0 -3 -3 -2 5 2 2 4 5 3 2 3 5 2 3 3 2 1 29 16 5 0 1 3 0.52 1.93 169 K -1 2 -1 0 -2 2 0 -3 0 -3 -4 2 -3 -4 4 1 -1 -2 -3 -3 5 12 3 5 1 7 6 2 2 1 2 12 1 1 22 10 3 1 1 2 0.43 1.94 170 D -1 -2 2 4 -3 1 1 -1 -1 -2 -3 -1 -3 -3 0 1 1 0 -3 -2 4 2 10 22 1 5 10 5 1 2 3 4 1 1 6 10 7 1 1 3 0.32 1.92 171 A 0 -1 0 1 -3 0 2 1 1 -2 -2 -1 -1 -3 3 1 0 -2 -3 -3 8 3 4 7 1 4 14 10 4 3 5 4 1 1 14 9 5 1 1 2 0.20 1.92 172 A 1 0 1 0 -1 1 1 0 0 -2 -1 -1 2 -2 -1 2 1 -3 -3 -1 10 4 7 5 1 6 7 6 2 2 7 3 5 2 3 12 9 0 1 5 0.09 1.93 173 I 0 -1 0 1 -3 -1 0 -2 -3 1 0 -1 3 -2 -1 0 1 -2 -3 1 9 4 5 8 1 3 6 4 1 6 9 4 7 2 3 8 9 1 1 10 0.10 1.93 174 T 1 -2 0 1 -2 0 1 -1 -2 0 0 0 0 -2 -1 2 1 -5 -3 -2 12 2 5 9 1 4 8 5 1 6 9 5 3 2 3 15 8 0 1 3 0.11 1.95 175 L -1 -2 -2 -2 -2 -1 -2 -3 -2 1 3 -2 5 2 0 -1 0 -2 -1 1 4 2 2 2 1 3 3 2 1 8 23 3 12 8 5 4 5 0 2 9 0.28 1.94 176 K 0 -1 1 0 -4 2 2 -1 -1 -2 -2 1 3 -4 -2 1 0 -4 -3 -2 8 4 6 5 0 8 15 4 2 3 5 9 7 1 2 11 6 0 1 3 0.21 1.97 177 A 1 -2 2 4 -1 0 2 -2 3 -4 -3 -1 0 -2 -4 0 -1 -2 -1 -2 10 2 11 20 1 4 14 4 6 1 3 3 2 2 1 6 3 1 2 4 0.34 1.99 178 I 0 -2 -2 -1 -3 2 -1 -4 0 2 1 -2 4 -1 -3 0 2 -3 1 1 9 2 2 3 0 10 3 1 2 10 12 2 9 2 1 6 12 0 4 8 0.24 2.01 179 N 0 2 2 -1 -4 1 1 0 0 -3 -4 2 -2 -2 0 0 -1 -4 -2 0 7 12 9 3 0 6 8 8 3 1 2 13 1 2 4 7 4 0 1 7 0.20 2.04 180 P 0 -1 -2 -1 -3 1 -1 -2 4 0 0 2 0 0 0 -2 -1 0 1 -1 8 4 2 4 0 7 4 3 9 5 9 14 2 5 5 3 4 1 5 5 0.16 2.03 181 I 0 -1 -2 -4 1 4 0 -3 0 1 -1 0 0 -2 -2 0 -1 -3 -2 2 9 3 2 1 3 18 6 2 2 9 7 6 2 2 2 7 3 0 2 14 0.25 2.03 182 N 1 -1 4 -2 1 2 -2 -2 0 2 -3 -1 2 -3 -2 0 0 -5 0 0 10 4 19 2 3 11 2 3 2 10 2 4 5 1 2 7 6 0 3 5 0.30 2.04 183 T -1 3 2 0 -1 2 1 -3 0 -2 -1 1 -1 -2 -4 1 0 -3 -2 -1 6 16 8 5 1 7 8 2 2 3 7 10 2 2 1 8 7 0 1 4 0.20 2.10 184 F -1 -5 -6 -6 1 -5 -5 -5 -4 3 3 -5 -1 4 -6 -4 -2 -3 -3 4 6 0 0 0 3 0 0 1 0 17 22 0 1 14 0 1 3 0 1 29 0.79 2.12 185 T -2 -5 -5 -6 -2 -4 -6 -6 -5 4 2 -5 4 0 -6 -4 1 -6 -4 5 3 0 0 0 1 1 0 0 0 18 17 0 9 4 0 1 8 0 0 37 0.91 2.13 186 K -1 2 -2 -1 -2 3 5 -4 1 -3 -3 2 -3 -4 -5 -1 0 -5 -1 -3 5 9 2 3 1 13 33 1 3 2 2 10 1 1 0 4 6 0 2 1 0.59 2.14 187 F -1 -2 -1 1 0 -2 -2 -5 -1 0 1 -3 2 5 -3 -3 2 -1 2 0 5 2 3 8 2 2 2 1 2 5 13 2 5 21 1 2 11 1 5 6 0.35 2.14 188 L -4 -6 -6 -6 -1 -6 -6 -6 -6 3 6 -6 5 1 -5 -5 -4 -2 -4 -1 1 0 0 0 1 0 0 0 0 13 60 0 13 6 0 0 0 0 0 2 1.29 2.15 189 L -4 -6 -7 -6 -4 -6 -7 -8 -7 7 3 -6 0 1 -6 -6 -4 -6 -3 1 1 0 0 0 0 0 0 0 0 61 23 0 2 5 0 0 1 0 0 5 1.50 2.12 190 D -2 0 1 2 -2 3 4 -4 -1 -2 -2 1 -2 -4 -5 0 2 -4 -4 -2 3 4 7 12 1 11 23 1 1 3 5 8 1 1 0 7 10 0 0 3 0.41 2.10 191 H -5 -2 6 -1 -3 1 0 -4 8 -5 -4 -2 -3 -2 -6 -2 -4 -4 3 -4 0 2 31 3 1 6 5 1 31 0 2 3 1 2 0 2 1 0 9 1 1.25 2.10 192 Q 1 -2 -2 -5 5 2 -3 -3 4 -3 -4 -1 -3 2 -3 0 -2 2 6 -1 11 2 2 0 10 9 2 2 9 1 2 3 0 8 1 7 2 3 22 5 0.62 2.11 193 G -2 -1 1 5 -2 1 3 -2 1 -3 -3 0 -4 -2 1 0 -2 -7 -2 -2 4 3 6 27 1 6 17 3 4 1 2 5 0 2 7 5 2 0 2 3 0.48 2.10 194 E -1 0 -2 1 -4 2 2 -4 0 -1 -1 1 -2 -2 -3 0 1 4 -1 0 6 4 2 8 0 10 15 1 3 4 6 9 1 2 1 7 8 4 2 6 0.22 2.10 195 L -3 -6 -7 -7 -4 -6 -6 -7 -7 6 4 -6 -1 2 -7 -4 -4 -6 -3 1 1 0 0 0 0 0 0 0 0 44 33 0 1 9 0 2 0 0 1 9 1.23 2.09 196 F -6 -7 -7 -8 -6 -7 -7 -7 -5 -4 -3 -7 -4 9 -8 -6 -6 4 2 -5 0 0 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 6 3 0 2.73 2.02 K Lambda Standard Ungapped 0.1368 0.3212 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.0994 0.3176 PSI Gapped 0.0304 0.2670