QUERY : TVAKAIFIKCGNLGTSMMMDMLLDERADREDVEFRVVGTSVKMDPECVEAAVEMALDIAEDFEPDFIVYGGPNPAAPGPSKAREMLADSEYPAVIIGDAPGLKVKDEMEEQGLGYILVKPDAMLGARREFLDPVEMAIYNADLMKVLAATGVFRVVQEAFDELIEKAKEDEISENDLPKLVIDRNTLLEREEFENPYAMVKAMAALEIAENVADVSVEGCFVEQDKERYVPIVASAHEMMRKAAELADEARELEKSNDAVLRTPHAPDGKVLSKRKFMEDPE : QUERY
UniRef90_H1KZN0 : -VVKIGILKCGNIGMSPIIDLCLDERADRKDIDVRVLGSGAKMDPTSVEEVATKM---VNEIKPDFIIYIGPNPAAPGPKKAREILSQSDIPAVIVGDAPGLRAKDEIEKEGLGYIIIKCDPMIGARRQFLDPVEMALFNADVIRVLAGTGALRIVQNAIDEMIESVKEGK--EVPLPKIVINEEKAVEAMEFTNPYAKAKAMAAFTIAEKVGDVDVKGCFMVKEMERYVPIVASAHEMLRYAAMLVDEARELEKAMDAVSRKPHHPEGKVLGKKKLMEKPE : UniRef90_H1KZN0
UniRef90_B8GJQ7 : -VVKVGIAKLGNIASGVMAELLLDERADREDMQTFMATSGTKLQPEDIDRVVSTM----KAWEPDFCIVVSPNGVLPGPVGARDELLKAGIPCVVITDDITTKKWEALKASSFGYIIMKADAMIGARREFLDPVEMADFNGNLVKVLALTGAFRKLQTELDKVIDQVKEGKKGDLVLPKVVMTSDKAVD-GEFSNPYALAKARAAYEIAQAVAGVNVKGCFMTKEWEKYIPIVASAHEMMRQAAALGDEAREIEKAGNGIIRKPHKKDGTIVSKITLISKPE : UniRef90_B8GJQ7
UniRef90_F7XNL9 : -MAKIGFIKLGNLGISQVIELVQDEIAAREGISIRVFGTGPKMGKDEAASTEQ---FKDMSWDADFYVIISPNASAPGPTAAREIWKD--VPCIIVSDGPTKKDRQALEEAGFGYIILKVDPLIGAKTEFLDSVEMASFNSDAMKVLSTCGVVRLIQEELDKVVEQVDAGKSGDIELPHILAKPEVCVERAGFENPYAKAKALASLFMAEKVAQINFPACFMMKELEDVALTTATGHEMMRAAAELAVQAREIEKINDTVSRHPHSKKGKVLSKTRLFEKP- : UniRef90_F7XNL9
UniRef90_E3GZ78 : -VVKIGVIKCGNIGTSPVIDLLLDERADRPNIDVRVIGSSAKMNPEQVEDVVPKMLDM----DRDLVIFISPNPGAPGPAKARELLSESDVPSIIIGDAPGKRVKDEIEKQGLGYIIVEADPMIGARREFLDPTEMASFNADVIKVLACTGAYRLIHKTLDDLISDLEAGK--EIELPKLIIDSEKAVEAGEFENPYAKAKAMAAYEIAAKAADLDVKGCFMVQDPEKYIPIVASAHEMVSIAAKLASEAREIEKSNDTVKRTPHGKKGELLEKVELMAKPK : UniRef90_E3GZ78
UniRef90_Q8THT2 : -MVNIGFIKMGNLGMSQVINLIQDEIAAREGITVRVFGTGAKMGPADAADTES-----FKQWNADFVVMISPNAAAPGPTAAREIWKD--VPCIVVSDGPTKKAREALEQEGFGYIILPVDPLIGAKREFLDPVEMASFNSDAMKVLSSCGVVRLIQEELDRVTEQVASGKSGEDELPHIFAKPEKCVEHAGFANPYAKAKALAALHMAEKVAQVNFPACFMLKEVEQVCLTAAAGHEIMGAAAILATQAREIEKSNDTVFRQPHAKNGTLLKKVKLYEKPE : UniRef90_Q8THT2
UniRef90_Q2NHQ2 : -VVKIGIVKVGNIGTSVLIDMILDERADREDIDVRTISSGAKMGKNQMDDV----LPKIDEYNPDVIIFISPDPGAKSPSSARETLSKKNIPTIVIGDGPGERAIGSMKEQGLGYIIVKADSMIGARREFLDATEMAVFNSDVLMVLSTTGVFRLIHKTLDKVIRDIDEDKLYS--LPELVITAENAVDAADFKNPYAKSKAIAAYSIACQVSSMNVRACFKTKDYHVYIPLVSAAHEMMSAASKLAYEAREIEKSNDTVVRTAHRRNGSILYGTSLNDNKE : UniRef90_Q2NHQ2
UniRef90_D7EB48 : -MVKVGFIKLGNLGMSQVVDLLEDEIAAREGITTRVYGTGPKMSKEDAADTE----AFKEEFDPDFVIIISPNASTPGPTEARQLWKDK--PCLIISDGPTKKDRQAIEDEGFGYIILPVDPLIGAKTEFLDPEEMASFNSDVMKVLSTCGAVRLVQEELDKLTSQVDEGKSGEIEMPHIYAKPQTCIERSGFSNPYAKAKALAALHMAEKVSQINLPACFMLKDLEEVAFTAATGHEMIRAAAELAVEAREIEKTNDTVLRKPHSKKGKVLSKTKLYEKPQ : UniRef90_D7EB48
UniRef90_U6EAV6 : -VVKIGVIKSGNIGTSPVLDLVLDERADRPNIDVRGVGSGAKMNPEQVEEVVPKIM----DFDPDFVIFISPNPGAPGPAKARELLSEMDIPALIIGDAPGMGKREEMDEQGLGYIVVLGDPMIGARREFLDPTEMASFNADVIKVLAATGAYRVVQETIDEMIAACEAGK--DIELPKVVIDAATATEAAGFANPYAKAKAMAAYEMAAKVGDIDLKGCFMVKDMEKYIPIVASAHELIAAAAQLATEAREIEKANDTVLRKPHGSKGQTMSKTVLVSKPE : UniRef90_U6EAV6
UniRef90_F2KNE0 : ---RIGIIKLGAIATALLIDYMLDERADREDIDVRTITSGSKLRERDAEIV-----DKMREFNPDLVIVASPNAALPAAKLARDALKAEGKPVIVISDAPAKKVKDELEAEGFGYILVNADSMIGARREFLDPTEMCLYNSDVIKVLAATGAFRAVQLAVDEAIESAKAGK---PKLPRLIIDAEAAVNAGNFSNPYARAKAMAAYTIAEKVAAVTTKACFVEKDAEKYIPMVAAAHEMMRYAAKLAEEAREIEKSSDAVYRTPHAKDGRVLSKWGLMEKP- : UniRef90_F2KNE0
UniRef90_Q648F7 : -IVKIGFVKLGNIGISRIVDLLLDERADREDIDVRVLGTGAKMTPENAADTSRLL-----DWDPDVVVITSPNAALPGPKSAREMVKEKGKPCIVISDAPAKKAVDKLKEGGFGYIIIPGDPMIGARREFLDPVEMSLFNADVLSVLSITGVAKLVQEEIDAVIEAIKKGE--EVKVPQIIATAERAVERAKFSNPYAKAKAIAAYSMAEKVAELDVKGCFMMKNPEEYVPVVAAAHELLREAAKLAFEAREVEKQTDSLVREPHSRTGEIMKKEKLMEKP- : UniRef90_Q648F7
UniRef90_H8I793 : -TVRVGVVKLGNLGTSRYIDLILDERADR-DIYTRVVGTGTKLGEPDAEEAATKIL----DFKPQLAIVISPNGALPGPTKAREMIKAAGVPTIMISDAPAAKVKDDLKAKGFGFFIIKCDSMIGARRQFLDPTEMVLFNADLQKVLADTGVVRLLQKELDRVVAEIASGAT--PNLPQIVVDSNKALAESGYKNPYARAKAFAAFAAAEKVGDIDVLGCFVQKEMEQYVITVASAHELLRAAAMLCDEAREIEKSGDSVYRTPHANDGKILSKSTLVSKPE : UniRef90_H8I793
UniRef90_X1RFV6 : --FKLGVIKFGCIGAAPLLDLIVDERADRKDLEVMVFTSGAKLDPDSCISPTEAVI----EYKPHLVLSVSPNAALPGPTKSREMLCEAKLPTITISDGPGKKVKSILE--GQGFIIIPSDSMIGARREFLDPTEMTLFNADMIKVLSCTGLMRLIQNEIDRVINEIKTGET--PKMPTVKASAEKAVKAGGFSNPYASAKAYAALKIAESVADVTVKGCFVVKDAAKYIPIVTAGHEMMRVAAMLSDEAREIEKYNDTVLRTPHHSKGTTLKKTKLPEKPE : UniRef90_X1RFV6
UniRef90_D5VSM6 : -MVKVGIVKCGNIGTSLVVDLALDERAER-DINVLVYGSGAKMNPESVEYVVKKMI----EEKPDLIIYIGPNPAAPGPRKARELLSECKIPSIIIGDAPGIKVKDEMEKEGLGYILIKGDPMIGARREFLDPTEVALFNSDILKVLAVTGVVRLVQEEIDRVIEYIKEGK--EPELPRIVVDAEKAVERMEYSNPYAKAKAIASYNMAEEVANIDVKACFMVKEPERYIILAASAHELLRQAAKLADEARELEKATDMVSRKPHAKDGRILSKRKLLEKPQ : UniRef90_D5VSM6
UniRef90_R9SJF9 : -VVKIGIVKSGNIGASPVLELLLDERADRPNIDVRVFTSGAKMNPEQVEDVVPK----VKDFNPDFVMFSSPNPTAPGPAKARELLSEMDVPAFIIGDAPGKRAKDEMDEQGIGYIIVEADSMIGARREWLDPTEMSVFNSDLIKVLACTGAYRLIQNTIDGVIAQADAGE--EIELPKLVINAQKAVDAAGFTSPYAKAKAYAAYEMCAKVADLDMKGCFMMKNYEEFLPVVAAAHEMASAAAQLATEAREIEKANDTVLRTPHMSDGSTGKKVNLISKPE : UniRef90_R9SJF9
UniRef90_N0BIS0 : -MVKVGVVKMGAIGTALLVEYLLDERADREDITVRVVTSGAKMQPEEAEIV-----EKMKEFDPDLVIVVSPNAALPGPKAAREAFE--GKPVIVISDAPAKKAKEEFEEKGFGYILVNADSMIGARREFLDPTEMALFNSDVVKVLAATGAFRLVQEEIDKVIEALKEGKT--PELPKIVVTAEKAVKAGNFKNPYAKAKAMAAYYIAEKVADIDVKGCFIERDPEKYIPLVAAAHEMMRVAAIEADRAREIEKGGDSVYRNPHAKDGKILSKTSLMEKPQ : UniRef90_N0BIS0
UniRef90_N6VTP4 : -MIKIAIIKCGNIGMSPMIDLSLDERADREDIIIRVFGSGPKMDPESVEEVTKKAI----EENPNLIIYIGPNPSAPGPKKAIELLKECKIPSIIIGDAPGIKIKDKIAEAGLGYIIVKCDSMIGARREFLDPTEVGFFNSDIIKVLAGTGALRAVQMAIDKVISEIKEGK--EPELPKLIIDEEKAVEAMEFTNPYAKAKAMAAFVIAEKVGDIDVKGCFMVKEAEKYIPIVASAHEMLRYAAKLIDEARELEKANDAVSRKPHARDGRVLSKKRLMEKPQ : UniRef90_N6VTP4
UniRef90_F6D7B4 : -VVKIGVIKCGNLGTSPVIDLMLDERADRPNISVKSFGSGAKMGPEEIEEVVPKVADL----DAAFVIFISPNPAAPGPAKARELLSAMDVPAIIVGDGPGARVKDEMNEQGLGYILVKGDPMIGARREFLDPTEMASFNADVIKVLAATGAYRCVQKTLDA--LIAAAEAGEAIEVPKLVLTRDKAIAAAEFKNPYAKAKAMAAYTIAEKVADIDVEGCFMTKDAEKYIPIVASSHEMIAVAAKLAAEAREIEKANDTVLRTPHSGKGQLVSKTTLMSKPE : UniRef90_F6D7B4
UniRef90_G7WNZ3 : -MFKIGFIKLGNVASSLVADLALDEIAERTDVEVRSLSFGAKMTVKEAEMSAEL-----KGWGPQLVVIVGPNAATPGPTAARALYRD--VPTIVISDGPSKKAREALEAEGFGYIILPFDPLIGAKREFLDPAEMALFNSDALKVLSICGSVRLVQEELDGAMASIISG---APRLPTILSSPEGCTDRMAFRNPYARAKAIGALHMAQTVAGIDAAACFRLKELDRIALTAAAGHEVMRAAARLADEARELEKSTDSVSRRPHARSGAILAKTGLLDKPE : UniRef90_G7WNZ3
UniRef90_A0B7C4 : -MFKIGFIKLGNIASSLVVDLALDEIAERTEIESKVVSHGPKMSRGEGERLAEEM----RAWGPQMVVVVSPNAATPGPTAARSMLK--GIPLIVISDGPTKKARDAMETEGFGYIILPMDPLIGAKREFLDPAEMAIFNADALKVLSICGAVRLVQEEIDRAIASVAAGS---PQLPHILATPELCAERMDFANPYARAKAIAALYMAQTAASIDAQACFRLKELEAIALAAAAGHEVIRAAARLADEARELEKSGDTVSRKPHARSGDLLVKRKLLEKP- : UniRef90_A0B7C4
UniRef90_Q0W2P5 : -TVRVGIVKLGNIGTSRFIDLVLDERADR-DIYVRTVGAGAKMGEAEAEEM-----KKIIDFKPQFCIVISPNATVPGPTKAREMLKEAGIPTIVISDSPVLKIKDDLKAKGFGYFVVKCDPMIGARRQFLDPTEMVLFNADVLKVLANTGVVRLIQKELDAVIEGFAAGQT--PALPQIVISADKAVAAAGYKNPYAKAKAMAAFVAAEKVADIDLQGCFMQKEMEQYIPTVASAHELLREAAKLSDEARELEKATDAILRTPHAADGKVLSKTQLMLKPE : UniRef90_Q0W2P5
UniRef90_X1QSD2 : --VRIGLVKLGNIGTSTMLDLMLDERAEREDIDFRVVASGPKITEEDCEGVSEKIL----DFNPELIIAISPNPSLPGPSKAREILKKSGKPCVIIGDAPGAKIAGELEKAGFGFIFVEADSMLGARREFLDPIEMSLFNADVIKVLSVTGAFRVIFEETDKAIEGTKSGK---PYLPKVIVNRDKAVGAAKFENPYARAKAMAAFEIAKKVSGVSAEGCFKVKEREKYIPIVAAAHEMMSAAAKLCDEA-------------------------------- : UniRef90_X1QSD2
UniRef90_D2RET8 : ---RIGIAKLGAIGSAVLLEYCLDELAMRGDIETFVVSSGSKIKVEVLEEL--------EKRDFDLKIVTCPN--------AEKFLKDVNLSVIVITDRAS---KDWLDSLNWGYIVVKADAMIGARREFLDPTEMVLYNSDLLKVLAVTGIIRLLQYEINRALK--------EDYLPKVVVDYNTAVKFAGFCNPYARAKAIASYIIAENISKITHKACFVEKDAENYITLCATAHEMMRIAGKLADEAREIEKSNDSVLRTPHSKSGEILKKVGLYD--- : UniRef90_D2RET8
UniRef90_X1AM21 : -ILKIGILKNGTIGSSLLLAFLMDERAESKRINVREVTSGAKMNPEQCVETMQKLL----EFEPDLILMSSPNAALKGPKAARELT--GNVPTIVISDAPAKKAIDEFKERNMGYIIVGCDSMIGARRPFLDSVEMSCFNADLLKVLAITGVFNIITNELNKVIMDMLQGK--QPTLPQITINATNATEAAGFSNPYAQAKAFAAFELAASISKITGKTC-------------------------------------------------------------- : UniRef90_X1AM21
UniRef90_X1FPP7 : -VLKIGILKNGTIGSSLLLAFLLDERAESKNIIVREVTSGAKMNPECVETMKKLL-----EFEPELILMSSPNAALKGPKAAREL--AGNIPTIVISDAPAKKAIEEFKEKSMGYIIVGCDSMIGARRPFLDTVEMSCFNADLLKVLAITGVFNIIT----------------------------------------------------------------------------------------------------------------------------- : UniRef90_X1FPP7
: 1---------11--------21--------31--------41--------51--------61--------71--------81--------91--------101-------111-------121-------131-------141-------151-------161-------171-------181-------191-------201-------211-------221-------231-------241-------251-------261-------271-------28 :
OrigSeq : TVAKAIFIKCGNLGTSMMMDMLLDERADREDVEFRVVGTSVKMDPECVEAAVEMALDIAEDFEPDFIVYGGPNPAAPGPSKAREMLADSEYPAVIIGDAPGLKVKDEMEEQGLGYILVKPDAMLGARREFLDPVEMAIYNADLMKVLAATGVFRVVQEAFDELIEKAKEDEISENDLPKLVIDRNTLLEREEFENPYAMVKAMAALEIAENVADVSVEGCFVEQDKERYVPIVASAHEMMRKAAELADEARELEKSNDAVLRTPHAPDGKVLSKRKFMEDPE : OrigSeq
Jnet : -EEEEEEHHH--HHHHHHHHHHHHHHH-----EEEEEE--------HHHHHHHHHHHHHH-----EEEEEE-------HHHHHHHHHH----EEEE-----HHHHHHHHH----EEEE--------------HHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---------EEEE--HHHHHH------HHHHHHHHHHHHHHHH--------EE-----HHHHHHHHHHHHHHHHHHH-HHHHHHHH----EEEE-------EEEE-------- : Jnet
jhmm : -EEEEEHHHH--HHHHHHHHHHHHHHH-----EEEEEE---------HHHHHHHHHHHHH-----EEEEE--------HHHHHHHHHH----EEEE-----HHHHHHHHH----EEEE--------------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---------EEEE-HHHHHHH------HHHHHHHHHHHHHHHH--------EEE---EEEHHHHHHHHHHHHHHHHHHHHHHHHHH----EEEE-------EEEEEE------ : jhmm
jpssm : -EEEEEEEE----HHHHHHHHHHHHHH-----EEEEEE------HHHHHHHHHHHHHHHH-----EEEEEE--------HHHHHHHHH----EEEEE----HHHHHHHHH----EEEEE-------------HHHHH---HHHHHHHHHHHHHHHHHHHHHHHHHHHH----------EEEE---HHHHH-----HHHHHHHHHHHHHHHHH-----EEEEE-----HHHHHHHHHHHHHHHHHHH-HHHHHHHH----EEE-------EEEEE-------- : jpssm
Lupas 14 : --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CCCCCCCCCCCCCC-------------------------- : Lupas 14
Lupas 21 : -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CCCCCCCCCCCCCCCCCCCCCccccccc------------------- : Lupas 21
Lupas 28 : -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CCCCCCCCCCCCCCCCCCCCCCCCCCCC------------------- : Lupas 28
Jnet_25 : --BBBBBBBBBBBBBBBBBBBBBBBBB----B-BBBBBBB--B----B--BB--BB--B--B-BBBBBBBBBBB-B-BB--BB-BB----BBBBBBBB-BB--BB--B----BBBBBB-BBBBBBB---BBBBBBBBBBBB-BBBBBBBBBBB-BBB-BB--BB--B---------BB-BBB-B--BB----B-BBBBBBBB-BBB-BBB-BB-B-B-BBB----B--BBBBBBBBBBBBBBBB-BB--B--BB----BBBB-BB---B-BB----B----- : Jnet_25
Jnet_5 : ----BBBB-BBB-B-B-BB-BB-----------B-B-----------B--B---B----------BBBBBB----------B---------BBBBB-----------B-----B-BBB-B-----B---------BB-----BB-BBB---BB--B---B--BB--B---------B--B------B----------B-B-B-BBB-BB-------------------BB-BBB-B--BB--BB--B--B---------B---------------------- : Jnet_5
Jnet_0 : ----BB-B-----B-B--B--B---------------------------------------------BB------------B-----------BBB-------------------------------------------------BB----B----------------------------------B------------B-B------B---------B----------B--B--B--BB--B---B--B-------------------------------- : Jnet_0
Jnet Rel : 807888302067178999999999985278855888744788753218999999999862488845888704778876268999987538864887047751789988753886477614766666766652666643212489999999999999999999999985267877655347643131112136775279999999999999852788523331177721378999999999999861079988861587167516788741677313777899 : Jnet Rel
Notes
Key:
Colour code for alignment:
Blue - Complete identity at a position
Shades of red - The more red a position is, the higher the level of
conservation of chemical properties of the amino acids
Jnet - Final secondary structure prediction for query
jalign - Jnet alignment prediction
jhmm - Jnet hmm profile prediction
jpssm - Jnet PSIBLAST pssm profile prediction
Lupas - Lupas Coil prediction (window size of 14, 21 and 28)
Note on coiled coil predictions - = less than 50% probability
c = between 50% and 90% probability
C = greater than 90% probability
Jnet_25 - Jnet prediction of burial, less than 25% solvent accesibility
Jnet_5 - Jnet prediction of burial, less than 5% exposure
Jnet_0 - Jnet prediction of burial, 0% exposure
Jnet Rel - Jnet reliability of prediction accuracy, ranges from 0 to 9, bigger is better.