Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -3 -4 -2 -1 -3 -3 -2 1 2 -2 8 0 -3 -2 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.74 0.16 2 R -2 6 -1 -2 -4 2 0 -3 -1 -4 -3 3 -2 -4 -3 -1 -2 -3 -2 -3 0 80 0 0 0 9 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0.96 0.23 3 A 2 1 -2 -2 -3 -2 0 2 -2 0 -2 -1 -2 4 -3 -1 -2 -2 0 -1 30 11 0 0 0 0 6 21 0 7 0 0 0 25 0 0 0 0 0 0 0.28 0.24 4 L -2 -3 -4 -5 -2 -3 -4 -4 -3 0 4 -4 1 5 -4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 33 0 0 0 0 0 0 0.69 0.24 5 F -2 -3 -2 -3 -3 -2 -3 -3 4 -1 0 -3 -1 5 -4 -1 -1 0 5 -2 0 0 0 0 0 0 0 0 16 0 6 0 0 44 0 5 5 0 24 0 0.67 0.24 6 Y -3 -3 -3 -4 -3 -2 -3 -4 1 -1 1 -3 -1 2 -4 -3 -2 1 8 -1 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 81 0 1.05 0.24 7 K -1 1 2 -1 -3 0 -1 -2 -1 -3 -1 5 -2 -3 -2 1 -1 -3 0 -3 0 5 13 0 0 0 0 0 0 0 7 59 0 0 0 11 0 0 5 0 0.50 0.29 8 D -2 -2 3 6 -4 -1 2 -2 -2 -4 -2 0 -3 -4 -3 -1 -2 -5 -4 -4 0 0 18 58 0 0 15 0 0 0 4 5 0 0 0 0 0 0 0 0 0.85 0.32 9 G -1 -3 2 0 -4 -2 0 6 -2 -5 -5 -2 -4 -4 -3 -1 -2 -4 -4 -4 0 0 9 6 0 0 8 77 0 0 0 0 0 0 0 0 0 0 0 0 1.07 0.34 10 K -2 1 -1 -2 -4 0 1 -3 -2 -3 -3 6 -2 -4 -2 -1 -2 -4 -3 -1 0 0 0 0 0 0 6 0 0 0 0 88 0 0 0 0 0 0 0 6 0.87 0.34 11 L -2 -3 -5 -5 -2 -3 -4 -5 -4 3 5 -4 1 -1 -4 -4 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 25 75 0 0 0 0 0 0 0 0 0 0.78 0.34 12 F -3 -3 -4 -4 -3 -3 -4 -4 0 -2 -1 -3 -1 6 -4 -3 -3 1 7 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 0 0 51 0 1.24 0.34 13 T -2 -2 1 2 -4 -1 1 -3 2 -2 -1 0 -2 4 -3 -2 0 -1 4 -3 0 0 8 17 0 0 11 0 6 0 4 8 0 24 0 0 7 0 16 0 0.37 0.34 14 D -2 -2 0 7 -4 -1 0 -2 -2 -4 -4 -2 -4 -4 -2 2 -1 -5 -4 -4 0 0 0 77 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 1.09 0.34 15 N 1 1 4 -1 -3 0 -1 -2 -1 -4 -4 4 -2 -4 -2 1 0 -4 -3 -3 12 6 27 0 0 0 0 0 0 0 0 43 0 0 0 8 4 0 0 0 0.54 0.34 16 N 0 -1 3 4 -4 2 3 -2 -1 -4 -4 2 -3 -4 -2 -1 -2 -4 -3 -3 10 0 16 26 0 8 23 0 0 0 0 18 0 0 0 0 0 0 0 0 0.55 0.34 17 F -2 0 1 -2 3 -1 1 -4 -2 -1 2 0 -1 3 -3 -2 -2 -2 2 -2 0 6 9 0 10 0 16 0 0 0 23 7 0 19 0 0 0 0 10 0 0.28 0.34 18 L -1 -2 -2 -2 -2 -1 1 -3 -3 2 1 1 -1 -2 -3 0 4 -4 -3 -1 0 0 0 0 0 0 9 0 0 16 15 13 0 0 0 4 43 0 0 0 0.35 0.34 19 N -2 2 3 -2 -3 2 -1 -3 1 2 0 1 1 -2 -3 -1 0 -3 -2 -1 1 15 20 0 0 15 0 1 4 20 7 8 4 0 0 0 4 0 0 0 0.25 0.30 20 P -1 2 -2 -2 -2 0 0 -2 1 1 0 -1 -1 0 4 0 -1 -2 -1 -1 5 16 1 1 0 5 7 1 5 13 10 1 0 5 21 5 1 0 1 1 0.25 0.26 21 V -1 -2 1 -2 -2 -2 -2 -3 -2 2 0 -2 0 -1 -2 -2 -1 -3 -2 5 2 1 9 1 0 1 1 1 0 7 2 1 0 1 1 1 1 0 1 68 0.44 0.26 22 S -1 -2 -1 -1 -3 -1 2 -2 1 -2 -2 0 -2 -3 5 2 -1 -3 -2 1 1 1 1 1 0 1 15 1 4 1 1 5 0 0 34 21 1 0 0 13 0.57 0.28 23 D 0 0 1 4 1 -1 1 0 -1 -1 -2 -1 -2 0 -2 1 0 -2 1 -2 6 6 4 28 4 1 9 5 0 4 1 1 0 4 1 8 8 0 8 1 0.23 0.28 24 D -1 -2 2 5 -3 -1 0 -2 -2 -3 -1 0 -3 -4 -2 2 -1 -4 -3 -3 0 0 10 49 0 0 0 0 0 0 7 6 0 0 0 27 0 0 0 0 0.61 0.28 25 N -2 -1 7 0 -3 -1 -1 -1 0 -4 -4 1 -3 -4 -3 0 1 -4 -3 -3 0 0 77 0 0 0 0 0 0 0 0 12 0 0 0 0 11 0 0 0 0.90 0.28 26 P 0 -1 -2 -1 -4 -1 2 -3 -2 -3 -1 2 -2 -4 6 -1 -2 -4 -3 -3 6 0 0 0 0 0 18 0 0 0 9 21 0 0 47 0 0 0 0 0 0.89 0.28 27 A 2 -2 -2 -2 -2 -2 -2 -2 -3 -1 2 -2 0 -2 -2 0 4 -3 -2 -1 28 0 0 0 0 0 0 1 0 0 28 0 0 0 0 1 38 0 0 0 0.34 0.26 28 Y -2 -2 0 -3 -3 -2 -2 -3 1 0 -2 0 -1 2 -3 -2 -2 1 7 -1 1 1 6 1 0 1 1 1 0 6 1 6 0 0 1 1 1 0 71 1 0.84 0.24 29 E -1 -1 4 3 -4 0 4 -2 -1 -4 -3 0 -3 -4 -2 -1 -1 -4 -3 -3 6 0 28 14 0 0 46 1 0 0 1 0 0 0 0 1 0 0 0 0 0.63 0.26 30 V -2 -4 -4 -4 -2 -4 -4 -5 -4 5 1 -4 0 -1 -4 -3 -1 -4 -2 4 0 0 0 0 0 0 0 0 0 68 0 0 0 0 0 0 0 0 0 32 0.74 0.28 31 L -2 -4 -4 -4 -2 -3 -4 -5 -4 4 4 -4 1 -1 -4 -3 -2 -3 -2 2 0 0 0 0 0 0 0 0 0 47 47 0 0 0 0 0 0 0 0 6 0.66 0.28 32 Q 1 2 1 1 -3 1 1 -2 -2 -1 -3 4 -2 -4 -2 -1 -1 -4 -3 -2 15 9 6 6 0 3 9 0 0 7 0 44 0 0 0 0 0 0 0 0 0.39 0.28 33 H -1 2 1 -2 -4 0 0 -2 5 -4 -3 4 -2 -3 -2 -1 -2 -3 1 -3 5 13 7 0 0 0 0 0 23 0 0 47 0 0 0 0 0 0 4 0 0.59 0.28 34 V -2 -3 -4 -4 -2 -3 -3 -4 -1 3 0 -3 -1 1 -4 -3 -2 0 6 3 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 44 29 0.66 0.28 35 K -2 4 -1 -2 -4 1 0 -3 -1 -4 -3 6 -2 -4 -2 -1 -2 -4 -3 -3 0 27 0 0 0 0 0 0 0 0 0 73 0 0 0 0 0 0 0 0 0.87 0.28 36 I -2 -4 -4 -4 -2 -3 -3 -4 -4 5 0 -3 0 -2 5 -3 -2 -4 -3 2 0 0 0 0 0 0 0 0 0 60 0 0 0 0 29 0 0 0 0 11 0.76 0.28 37 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.36 0.28 38 T 1 -1 0 -1 -3 -1 0 -2 -2 -3 -3 2 -2 -4 4 2 1 -4 -3 -2 16 0 4 0 0 0 4 0 0 0 0 21 0 0 24 24 7 0 0 0 0.52 0.28 39 H -3 -1 0 -2 -4 -1 -1 -3 9 -4 -3 -2 -2 -1 -3 -2 -3 -2 4 -4 0 0 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 0 15 0 1.36 0.28 40 L -2 -3 -4 -5 -2 -3 -4 -5 -4 1 5 -3 1 0 -4 -3 -2 -3 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.85 0.28 41 T -1 -1 3 -1 -3 -1 -1 -2 5 -3 -3 2 -2 -3 -2 1 4 -4 -1 -2 0 0 16 0 0 0 0 0 19 0 0 15 0 0 0 5 45 0 0 0 0.52 0.28 42 D -3 -2 4 6 -4 -1 1 -2 -1 -4 -5 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 26 69 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 1.06 0.28 43 V -1 -4 -4 -4 -2 -3 -4 -4 -4 4 0 -3 0 -1 -3 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 33 0 0 0 0 0 0 0 0 0 67 0.70 0.28 44 V 0 0 -2 -2 -3 1 2 -3 -2 3 -1 0 1 -2 -3 -2 0 -4 -2 2 6 6 0 0 0 5 16 0 0 30 0 7 4 0 0 0 6 0 0 19 0.23 0.28 45 V -2 -3 -4 -4 -2 -3 -4 -4 -4 2 3 -3 1 1 -4 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 11 35 0 0 6 0 0 0 0 0 48 0.55 0.28 46 Y -2 -3 -3 -4 -3 -3 -3 -4 0 3 0 -3 -1 1 -4 -3 -2 0 6 2 0 0 0 0 0 0 0 0 0 29 6 0 0 0 0 0 0 0 53 12 0.73 0.28 47 E 3 -1 -1 0 -3 1 5 -2 -1 -3 -3 0 -2 -4 -2 0 -1 -4 -3 -2 35 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 0 0.71 0.28 48 Q -2 1 1 -1 -4 6 1 -2 -1 -4 -3 3 -2 -4 -2 -1 -1 -3 -2 -3 0 0 6 0 0 65 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0.82 0.28 49 T -1 -2 4 1 -2 -1 -1 -2 -2 -2 -3 -1 -2 -3 -2 1 5 -4 -3 -2 0 0 29 5 0 0 0 0 0 0 0 0 0 0 0 9 57 0 0 0 0.64 0.28 50 W -2 -3 -4 -4 -3 -3 -4 -4 -1 3 2 -3 0 1 -4 -3 -2 5 5 1 0 0 0 0 0 0 0 0 0 24 20 0 0 0 0 0 0 8 37 12 0.61 0.28 51 E -1 -1 -1 3 -4 1 5 -3 -1 -4 -4 1 -3 -4 -2 1 -1 -4 -3 -3 0 0 0 13 0 0 68 0 0 0 0 7 0 0 0 12 0 0 0 0 0.80 0.28 52 E -2 -1 -1 2 -4 4 5 -3 -1 -4 -4 0 -2 -4 -2 0 -1 -4 -3 -3 0 0 0 8 0 27 60 0 0 0 0 0 0 0 0 5 0 0 0 0 0.83 0.28 53 A 5 -2 -2 -2 -1 -1 -1 -1 -2 -2 -3 -1 -2 -3 -2 3 0 -4 -3 -1 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0.64 0.28 54 L -1 -2 -1 4 -3 1 -1 -3 1 -1 3 -2 0 -2 -3 0 -2 -3 -2 -2 6 0 0 35 0 11 0 0 4 0 39 0 0 0 0 5 0 0 0 0 0.37 0.28 55 T -2 2 5 0 -3 1 -1 -1 1 -3 -4 -1 -2 -4 -3 1 2 -4 -2 -3 0 11 47 0 0 9 0 4 4 0 0 0 0 0 0 7 17 0 0 0 0.56 0.28 56 R -1 2 -1 -2 -3 -2 -2 6 -2 -4 -4 0 -3 -4 -3 0 -2 -4 -4 -4 0 17 0 0 0 0 0 71 0 0 0 4 0 0 0 9 0 0 0 0 0.91 0.28 57 L -2 -3 -4 -4 -2 -3 -4 -5 -4 4 4 -3 1 -1 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 35 65 0 0 0 0 0 0 0 0 0 0.69 0.28 58 I -2 -4 -4 -4 -2 -4 -4 -5 -4 6 1 -4 0 -1 -4 -3 -1 -4 -2 3 0 0 0 0 0 0 0 0 0 83 0 0 0 0 0 0 0 0 0 17 0.79 0.28 59 F -3 -3 -4 -4 -3 -3 -4 -4 -1 -1 -1 -4 -1 7 -4 -3 -3 1 6 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 65 0 0 0 0 35 0 1.15 0.28 60 V -1 -4 -4 -4 -2 -3 -4 -4 -4 5 0 -3 0 -1 -3 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 46 0 0 0 0 0 0 0 0 0 54 0.70 0.28 61 G -1 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.44 0.28 62 S -1 1 -2 -3 4 -2 -2 -3 -2 1 2 0 -1 -2 -3 2 1 -3 1 0 0 9 0 0 12 0 0 0 0 8 22 8 0 0 0 22 8 0 6 5 0.20 0.28 63 D -3 -2 1 7 -5 -1 1 -2 -2 -4 -5 -2 -4 -5 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.39 0.28 64 S 1 -2 1 -1 2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -2 5 0 -4 -3 -2 9 0 6 0 6 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0.66 0.28 65 K -1 1 -1 -2 -4 1 0 -2 -2 -3 -3 6 -2 -4 -2 -1 0 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 93 0 0 0 0 7 0 0 0 0.86 0.28 66 G -1 -2 4 -1 -3 0 -2 5 -1 -4 -4 -2 -3 -4 -3 0 -1 -4 -3 -4 0 0 35 0 0 6 0 53 0 0 0 0 0 0 0 6 0 0 0 0 0.83 0.28 67 R -2 6 -1 -2 -4 0 0 -3 -1 -4 -3 4 -2 -4 -2 -1 -2 -4 -3 -3 0 58 0 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 0 0 0.92 0.28 68 R 0 4 -1 -2 -4 0 0 -2 -1 -4 -3 5 -2 -4 -2 -1 0 -4 -3 -3 6 24 0 0 0 0 0 0 0 0 0 67 0 0 0 0 4 0 0 0 0.74 0.28 69 Q -2 0 -1 -1 -4 7 1 -3 0 -4 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.14 0.28 70 Y -3 -3 -3 -4 -3 -2 -3 -4 1 -2 -2 -3 -2 2 -4 -3 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.45 0.28 71 F -3 -4 -4 -4 -3 -4 -4 -4 -3 3 0 -4 0 7 -4 -3 -2 -1 1 0 0 0 0 0 0 0 0 0 0 35 0 0 0 65 0 0 0 0 0 0 0.87 0.28 72 Y -3 -3 -3 -4 -3 -2 -3 -4 1 -2 -2 -3 -2 2 -4 -3 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.45 0.28 73 G -1 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.44 0.28 74 K -2 2 -2 -2 -3 0 -1 -3 -2 3 -1 5 -1 -3 -2 -2 -2 -4 -3 0 0 10 0 0 0 0 0 0 0 33 0 57 0 0 0 0 0 0 0 0 0.49 0.27 75 M -2 -2 5 0 -3 -2 -2 0 -2 -1 3 -2 3 -2 -3 -1 -1 -3 -2 -1 0 0 42 4 0 0 0 6 0 0 37 0 10 0 0 0 0 0 0 0 0.42 0.27 76 H -3 -1 -1 -3 -4 -1 -1 -3 8 -3 -3 -2 -2 2 -3 -2 -3 -1 5 -3 0 0 0 0 0 0 0 0 67 0 0 0 0 8 0 0 0 0 24 0 1.13 0.27 77 V -1 -4 -4 -4 -2 -3 -4 -4 -4 4 0 -3 0 -1 -3 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 0 70 0.69 0.27 K Lambda Standard Ungapped 0.1387 0.3221 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1685 0.3169 PSI Gapped 0.0516 0.2670