Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 C 0 -4 -3 -4 9 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.00 2 E -1 0 0 2 -4 2 5 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.02 3 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.49 0.02 4 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.90 0.02 5 H -2 0 1 -1 -3 0 0 -2 8 -4 -3 -1 -2 -1 -2 -1 -2 -3 2 -3 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0.91 0.02 6 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.90 0.02 7 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 -1 -4 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.02 8 E -1 0 0 2 -4 2 5 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.02 9 C -1 -4 -3 -4 9 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.26 0.02 10 V 2 -2 -3 -3 -1 -2 -2 -2 -3 2 0 -2 0 -1 -2 -1 0 -3 -2 4 29 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71 0.25 0.02 11 R -2 6 -1 -2 -4 1 0 -3 0 -3 -2 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.78 0.02 12 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.07 0.02 13 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.50 0.02 14 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.50 0.02 15 V 0 -3 -3 -3 -1 -2 -3 -3 -3 3 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.38 0.02 16 I -2 -3 -4 -4 -1 -3 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 24 76 0 0 0 0 0 0 0 0 0 0.42 0.02 17 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.49 0.02 18 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.55 0.02 19 E -1 0 0 2 -4 2 5 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.02 20 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.06 0.02 21 C -1 -4 -3 -4 9 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.26 0.02 22 P -1 -1 -1 -1 -3 3 0 -2 -1 -3 -3 0 -2 -4 7 -1 -1 -3 -3 -3 0 0 0 0 0 29 0 0 0 0 0 0 0 0 71 0 0 0 0 0 1.36 0.02 23 S 1 -1 0 -1 -1 0 0 -1 -1 -3 -3 -1 -2 -3 5 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 71 0 0 0 0 0.62 0.02 24 G 0 -2 3 0 -3 -1 -2 5 -1 -4 -4 -1 -3 -3 -2 0 -1 -3 -3 -3 0 0 29 0 0 0 0 71 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.02 25 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.50 0.02 26 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.90 0.02 27 E -1 0 0 2 -4 2 5 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.02 28 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.07 0.02 29 N -2 -1 6 1 -3 0 0 -1 1 -4 -4 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.02 30 S 1 -1 1 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.48 0.02 31 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.06 0.02 32 F -2 -3 -3 -4 -3 -3 -3 -3 0 -1 0 -3 0 6 -4 -2 -2 1 5 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 71 0 0 0 0 29 0 0.72 0.02 33 H -2 0 1 -1 -3 0 0 -2 8 -4 -3 -1 -2 -1 -2 -1 -2 -3 2 -3 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0.92 0.03 34 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.07 0.03 35 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.49 0.03 36 A 4 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.44 0.03 37 D -2 -2 1 6 -4 0 2 -2 -1 -3 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.03 38 N -2 -1 6 1 -3 0 0 -1 1 -4 -4 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.77 0.03 39 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.56 0.03 40 F -2 -3 -3 -4 -3 -4 -4 -3 -1 0 0 -3 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.79 0.03 41 A 4 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.44 0.03 42 L -2 -3 -4 -4 -1 -3 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 37 63 0 0 0 0 0 0 0 0 0 0.41 0.03 43 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.51 0.03 44 C -1 -4 -3 -4 10 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.27 0.03 45 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.51 0.03 46 S 0 -1 4 0 -2 0 0 0 0 -3 -3 0 -2 -3 -1 3 1 -3 -2 -2 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0.45 0.03 47 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.51 0.03 48 H -1 1 0 -1 -3 1 0 -2 7 -3 -3 3 -2 -2 -2 -1 -1 -3 1 -3 0 0 0 0 0 0 0 0 63 0 0 37 0 0 0 0 0 0 0 0 0.59 0.03 49 F -2 -3 -3 -4 -3 -4 -4 -3 -1 0 0 -3 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.79 0.03 50 A 4 -1 -1 -1 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 3 1 -3 -2 -1 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0.37 0.03 51 F -2 -3 -3 -4 -3 -4 -4 -3 -1 0 0 -3 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.79 0.03 52 A 3 -2 -2 -2 -1 -1 -2 -1 -2 1 -1 -1 0 -2 -1 0 0 -3 -2 2 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37 0.26 0.03 53 C -1 -4 -3 -4 10 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.27 0.03 54 A 3 0 -1 -1 -1 3 0 -1 -1 -2 -2 0 -1 -3 -1 1 0 -3 -2 -1 63 0 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.34 0.03 55 D -2 -2 1 6 -4 0 2 -2 -1 -3 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.03 56 G 0 -1 0 0 -3 0 3 5 -1 -4 -4 -1 -3 -4 -2 0 -1 -3 -3 -3 0 0 0 0 0 0 37 63 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.03 57 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.51 0.03 58 R -2 6 -1 -2 -4 1 0 -3 0 -3 -2 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.79 0.03 59 H -2 0 1 -1 -3 0 0 -2 8 -4 -3 -1 -2 -1 -2 -1 -2 -3 2 -3 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0.92 0.03 60 T 0 -2 -1 -2 -1 -1 -2 -2 -2 1 0 -1 0 -2 -2 1 4 -3 -2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 0 0 37 0.31 0.03 61 Y -2 -2 -3 -4 -3 -2 -3 -3 1 -1 -1 -3 -1 5 -4 -2 -2 2 6 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 63 0 0.76 0.03 62 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 -1 -4 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.69 0.03 63 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.49 0.03 64 R -2 6 -1 -2 -4 1 0 -3 0 -3 -2 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.79 0.03 65 A 4 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.44 0.03 66 R -2 6 -1 -2 -4 1 0 -3 0 -3 -2 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.79 0.03 67 S 1 -1 1 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.49 0.03 68 V -1 -3 -3 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 0 63 0.38 0.03 K Lambda Standard Ungapped 0.1350 0.3234 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1426 0.3177 PSI Gapped 0.0436 0.2670