Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 K -1 2 -1 -1 -4 3 1 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 22 0 0 0 0 0 78 0 0 0 0 0 0 0 0 0.70 0.16 2 T 0 -2 -1 -2 -2 -1 -1 -2 -2 -1 -1 -1 2 -2 -2 3 4 -3 -2 1 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 33 42 0 0 13 0.40 0.21 3 S 1 -1 3 -1 -2 -1 -1 -1 -1 -3 -3 -1 -2 -3 -2 4 2 -4 -2 -2 11 0 25 0 0 0 0 0 0 0 0 0 0 0 0 50 14 0 0 0 0.50 0.21 4 P -1 -3 -2 -2 -3 -2 -2 -3 -3 -3 -3 -2 -3 -4 8 -1 1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89 0 11 0 0 0 1.96 0.21 5 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.35 0.21 6 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -2 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.32 0.21 7 E -2 -1 -1 0 -4 3 5 -3 -1 -3 0 0 -1 -3 -2 -1 -1 -3 -2 -2 0 0 0 0 0 16 70 0 0 0 14 0 0 0 0 0 0 0 0 0 0.68 0.21 8 L -2 -3 -4 -4 -2 -3 -4 -4 -3 4 3 -3 1 2 -4 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 56 31 0 0 13 0 0 0 0 0 0 0.55 0.21 9 T 0 -1 4 1 -3 -1 -1 -2 3 -3 -3 -1 -2 -2 -2 0 2 -3 2 -2 11 0 38 8 0 0 0 0 13 0 0 0 0 0 0 0 23 0 8 0 0.43 0.21 10 S -1 -2 4 -1 -2 -1 -1 1 -1 -3 -3 -1 -2 2 -2 3 0 -3 -1 -3 0 0 33 0 0 0 0 11 0 0 0 0 0 13 0 44 0 0 0 0 0.45 0.21 11 T -1 -2 -1 -2 -2 -2 -2 1 -3 3 -1 -2 -1 -2 -2 2 2 -3 -2 0 0 0 0 0 0 0 0 13 0 43 0 0 0 0 0 26 17 0 0 0 0.28 0.21 12 T 1 -2 -1 -2 -1 -1 -1 -1 -2 1 -2 -1 -1 -3 -2 3 3 -3 -2 -1 13 0 0 0 0 0 0 0 0 13 0 0 0 0 0 43 31 0 0 0 0.40 0.21 13 L 0 -2 -1 -2 -2 -1 -2 -2 -2 -1 3 -2 0 -1 -2 4 0 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 44 0 0 0 0 56 0 0 0 0 0.37 0.21 14 N -2 -1 3 3 -4 5 1 1 -1 -4 -4 0 -2 -4 -2 -1 -1 -3 -3 -3 0 0 17 27 0 43 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0.60 0.21 15 K -2 -1 5 4 -4 0 0 -1 -1 -4 -4 2 -3 -4 -2 0 -1 -4 -3 -4 0 0 56 26 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0.75 0.21 16 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.28 0.21 17 S -1 0 -1 -2 -3 2 0 -2 -2 -2 0 3 -1 -3 4 1 -1 -3 -3 -2 0 0 0 0 0 16 0 0 0 0 14 27 0 0 25 17 0 0 0 0 0.48 0.21 18 T 1 -2 -1 -2 -1 -1 -2 -2 -2 -1 -1 -1 3 -2 -2 0 5 -3 -2 1 13 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 65 0 0 9 0.47 0.21 19 F -3 -4 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 -1 7 -4 -3 -3 0 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.18 0.21 20 K -1 1 -1 -1 -4 1 2 -2 -1 0 -2 5 -2 -3 -2 -1 -1 -4 -2 -2 0 0 0 0 0 0 13 0 0 13 0 75 0 0 0 0 0 0 0 0 0.57 0.21 21 K -1 1 -1 -1 -4 3 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 16 0 0 0 0 0 84 0 0 0 0 0 0 0 0 0.77 0.21 22 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.76 0.21 23 D -2 -2 5 5 -4 -1 0 -1 -1 -4 -4 -1 -3 -4 -2 1 -1 -5 -3 -4 0 0 38 55 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0.87 0.21 24 S -1 0 0 1 -2 2 0 -2 -1 -2 0 2 -1 -3 -2 3 0 -3 -2 -2 0 0 0 11 0 16 0 0 0 0 14 16 0 0 0 43 0 0 0 0 0.31 0.21 25 F -3 -3 -4 -4 -3 -4 -4 -4 -2 2 2 -4 0 6 -4 -3 -2 0 1 0 0 0 0 0 0 0 0 0 0 13 26 0 0 61 0 0 0 0 0 0 0.72 0.21 26 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 3 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 87 0 13 0 0 0 0 0 0 0 0.70 0.21 27 H -1 0 -1 0 -3 4 3 1 4 -3 -3 0 -2 -3 -2 -1 -1 -3 -1 -3 1 1 0 1 0 27 33 14 18 1 1 1 0 0 1 1 1 0 0 1 0.49 0.18 28 S 0 -1 0 0 -2 0 3 -2 -1 -3 -3 0 -2 -3 -2 4 2 -3 -2 -2 0 0 0 0 0 0 33 0 0 0 0 0 0 0 0 57 11 0 0 0 0.54 0.21 29 T 1 0 -1 -1 -2 0 -1 -2 -2 -2 -3 3 -2 -3 -2 3 3 -3 -2 -2 11 0 0 0 0 0 0 0 0 0 0 33 0 0 0 27 30 0 0 0 0.41 0.21 30 D -1 3 -1 2 -2 -1 -1 -2 -2 1 -1 1 -1 -2 -2 0 -1 -3 -2 1 1 25 1 18 0 1 1 1 0 14 1 11 0 0 1 9 1 0 0 14 0.21 0.18 31 V 1 -2 -1 -2 -1 -1 -1 -1 -2 2 -1 -1 -1 -2 -1 1 2 -2 -2 2 14 1 1 1 0 1 2 2 1 14 2 1 1 1 1 16 21 0 1 19 0.17 0.16 32 N -2 -1 5 3 -3 -1 0 -1 -1 -3 -3 -1 -2 -3 -2 0 1 -4 -3 -3 1 0 55 24 0 0 1 1 0 0 1 0 0 0 0 1 14 0 0 1 0.66 0.19 33 I -2 -3 -3 -3 -2 -3 -3 -4 -3 4 0 -3 0 -2 4 -2 1 -4 -2 1 0 0 0 0 0 0 0 0 0 61 0 0 0 0 25 0 14 0 0 0 0.59 0.21 34 N -2 0 4 0 -4 4 2 -2 0 -4 -3 3 -2 -4 -2 0 -1 -3 -2 -3 0 0 28 0 0 33 14 0 0 0 0 25 0 0 0 0 0 0 0 0 0.59 0.21 35 T -2 -1 5 3 -3 -1 2 1 -1 -3 -4 -1 -3 -4 -2 0 2 -4 -3 -3 0 0 40 16 0 0 14 13 0 0 0 0 0 0 0 0 17 0 0 0 0.52 0.21 36 V -1 -3 -4 -4 -2 -3 -3 -4 -4 4 2 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 30 13 0 0 0 0 0 0 0 0 57 0.56 0.21 37 F -3 -4 -4 -4 -3 -4 -4 -4 -2 1 0 -4 0 7 -4 -3 -3 0 2 -1 0 0 0 0 0 0 0 0 0 13 0 0 0 87 0 0 0 0 0 0 1.00 0.21 38 P -1 -2 -2 -2 -3 -2 -2 -2 -3 -3 -4 -1 -3 -4 7 1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81 19 0 0 0 0 1.74 0.21 39 G -1 0 2 -1 -4 0 2 3 3 -4 -4 3 -3 -4 -2 -1 -2 -4 -2 -3 0 0 11 0 0 0 14 30 13 0 0 33 0 0 0 0 0 0 0 0 0.47 0.21 40 I -2 -3 -4 -4 -2 -3 -4 -4 -4 4 3 -3 1 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 44 43 0 0 0 0 0 0 0 0 13 0.56 0.21 41 G 1 -2 4 -1 -2 -1 -1 3 -1 -3 -4 -1 -3 -3 -2 2 0 -4 -3 -3 14 0 33 0 0 0 0 28 0 0 0 0 0 0 0 25 0 0 0 0 0.53 0.21 42 D 0 -2 5 5 -3 -1 0 -1 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -3 13 0 43 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.21 43 N -2 -1 6 2 -3 -1 -1 -1 0 -4 -4 -1 -3 -4 -2 1 0 -4 -3 -3 0 0 75 13 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0.86 0.21 44 V -1 -3 -4 -4 -2 -3 -3 -4 -4 3 3 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 14 33 0 0 0 0 0 0 0 0 53 0.53 0.21 45 K -1 0 -1 -2 -2 0 -1 -2 -2 -2 -2 4 -2 -3 -2 0 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 57 0 0 0 0.55 0.21 46 T 4 -2 -2 -3 -1 -2 -2 -1 -3 2 -1 -2 -1 -2 -2 0 2 -3 -2 2 52 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 17 0 0 14 0.35 0.21 47 T -1 -1 -1 0 -2 2 3 -2 -1 -2 -3 0 -2 -3 -2 1 4 -3 -2 -2 0 0 0 0 0 11 33 0 0 0 0 0 0 0 0 13 44 0 0 0 0.50 0.21 48 V -2 -3 -3 -4 -2 -3 -3 -4 3 1 0 -3 0 5 -4 -3 -2 -1 1 3 0 0 0 0 0 0 0 0 11 0 0 0 0 47 0 0 0 0 0 43 0.54 0.21 49 D 0 0 0 5 -3 0 0 -2 -2 -3 -3 4 -3 -4 -2 -1 -1 -4 -3 -3 13 0 0 44 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0.60 0.21 50 Q -2 1 4 0 -4 4 0 -2 0 -4 -3 4 -2 -4 -2 0 -1 -4 -2 -3 0 0 33 0 0 28 0 0 0 0 0 39 0 0 0 0 0 0 0 0 0.61 0.21 51 P 0 -3 -3 -2 -3 -2 -2 -3 -3 -3 -3 -2 -3 -4 8 -1 -2 -4 -4 -3 9 0 0 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0 2.01 0.21 52 K -1 1 -1 -1 -3 1 0 -2 -1 -3 -3 6 -2 -4 -2 1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 87 0 0 0 13 0 0 0 0 0.72 0.21 53 S 1 -2 -1 -2 -2 -1 -1 -2 -2 -2 -2 -1 -2 -3 3 3 4 -3 -2 -1 14 0 0 0 0 0 0 0 0 0 0 0 0 0 13 30 43 0 0 0 0.52 0.21 54 W -3 -3 -4 -5 -3 -3 -4 -3 -3 -2 1 -4 -1 3 -4 -3 -3 10 2 -2 0 0 0 0 0 0 0 0 0 0 16 0 0 16 0 0 0 67 0 0 1.79 0.21 55 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.76 0.21 56 S 1 -1 5 0 -2 0 -1 -1 -1 -3 -3 1 -2 -3 -2 2 0 -4 -3 -3 13 0 48 0 0 0 0 0 0 0 0 14 0 0 0 25 0 0 0 0 0.54 0.21 57 F 1 0 -2 -2 -3 -1 -1 -2 -2 -1 -1 4 -1 4 -2 -1 -1 -2 0 0 14 0 0 0 0 0 0 0 0 0 0 43 0 30 0 0 0 0 0 13 0.33 0.21 58 F -3 -3 -4 -4 -3 -4 -4 -4 -2 0 1 -4 0 7 -4 -3 -3 0 2 -1 0 0 0 0 0 0 0 0 0 0 13 0 0 87 0 0 0 0 0 0 1.01 0.21 59 T -1 -2 -1 -2 -2 -2 -2 -2 -3 1 -1 -1 -1 -2 -2 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 86 0 0 0 0.65 0.21 60 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.35 0.21 61 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -2 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.32 0.21 62 K -1 0 -1 0 -4 1 5 -3 -1 -4 -3 3 -2 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 0 66 0 0 0 0 34 0 0 0 0 0 0 0 0 0.78 0.21 63 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.35 0.21 64 T 0 -2 2 -1 -2 -1 -1 -2 -2 -2 -2 -1 -2 -3 -2 3 5 -3 -2 -1 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 35 57 0 0 0 0.57 0.21 65 I -1 -3 -4 -4 -2 -3 -4 -4 -4 4 2 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 44 13 0 0 0 0 0 0 0 0 43 0.57 0.21 66 T -1 -1 -2 -2 -2 -1 -2 -3 -3 3 1 1 0 -2 -2 1 3 -3 -2 0 0 0 0 0 0 0 0 0 0 33 13 14 0 0 0 11 30 0 0 0 0.26 0.21 67 L -2 -3 -4 -4 -2 -3 -4 -4 -3 3 3 -3 1 2 -4 -3 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 16 43 0 0 14 0 0 0 0 0 27 0.48 0.21 68 T 1 0 -1 -2 -2 1 0 -2 -2 -2 -2 3 -2 -3 -2 0 4 -3 -2 -1 13 0 0 0 0 9 0 0 0 0 0 35 0 0 0 0 44 0 0 0 0.43 0.21 69 D -2 -2 1 6 -3 -1 1 -2 -2 -3 -3 -1 -3 -3 -2 0 1 -4 -3 -3 1 1 0 76 0 0 1 1 0 1 1 1 0 0 1 1 14 0 0 1 0.85 0.18 70 N -1 0 2 3 -3 1 5 -2 -1 -3 -3 1 -2 -3 -2 -1 -1 -3 -2 -3 1 1 9 13 0 0 60 1 0 1 1 9 0 0 1 1 1 0 0 1 0.62 0.18 71 K 1 1 -1 -1 -3 3 0 -2 -1 -3 -3 4 -2 -4 -2 2 0 -3 -2 -2 11 0 0 0 0 17 0 0 0 0 0 45 0 0 0 26 0 0 0 0 0.47 0.21 72 T 1 -2 -1 -2 3 -1 -1 3 -2 -2 -2 -1 -2 -2 -2 1 3 -2 -2 -1 14 1 1 1 9 1 1 26 0 1 1 1 0 1 1 9 31 0 1 1 0.33 0.17 73 S -1 2 2 -1 -3 0 -1 3 -1 -3 -3 3 -2 -3 -2 2 -1 -3 -2 -3 1 14 11 0 0 0 1 25 0 0 1 26 0 0 0 18 1 0 0 1 0.37 0.19 74 A 3 -2 -2 -2 -2 -1 1 4 -2 -3 -3 -1 -2 -3 -2 0 -1 -3 -3 -2 48 0 0 0 0 0 14 38 0 0 0 0 0 0 0 0 0 0 0 0 0.56 0.21 75 Q -1 0 -1 -1 -3 3 3 -2 -1 -2 0 3 -1 -3 -2 1 -1 -3 -2 -2 1 0 0 0 0 18 24 1 0 0 15 25 0 0 0 13 0 0 0 0 0.32 0.19 76 A 5 -2 -2 -3 -1 -2 -2 -1 -2 -1 -2 -1 -1 -3 -2 0 -1 -3 -2 1 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 0.60 0.21 77 T -1 -1 2 0 -2 0 3 -2 -1 -3 -3 -1 -2 -3 -2 2 4 -3 -2 -2 0 0 14 0 0 0 35 0 0 0 0 0 0 0 0 13 38 0 0 0 0.48 0.21 78 I -2 -4 -4 -4 -2 -3 -4 -5 -4 6 1 -3 1 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.75 0.21 79 Q -1 0 -1 -1 -4 7 1 -2 0 -3 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.02 0.21 80 V -1 -3 -4 -4 -2 -3 -3 -4 -4 4 0 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 73 0.62 0.21 81 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -2 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.32 0.21 82 T -1 1 -1 -1 -3 1 0 -2 -1 -3 -3 5 -2 -4 -2 0 2 -4 -2 -2 0 0 0 0 0 0 0 0 0 0 0 83 0 0 0 0 17 0 0 0 0.67 0.21 83 P -1 -3 -3 -2 -4 -2 -2 -3 -3 -3 -4 -2 -3 -4 8 -1 -2 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.29 0.21 84 N 0 -2 4 -1 -2 -1 -1 3 -1 -4 -4 -1 -3 -3 -2 3 0 -4 -3 -3 0 0 28 0 0 0 0 25 0 0 0 0 0 0 0 47 0 0 0 0 0.57 0.21 85 I -2 -4 -4 -4 -2 -3 -4 -4 -4 5 2 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 70 14 0 0 0 0 0 0 0 0 16 0.62 0.21 86 F -2 -3 -4 -4 -2 -3 -4 -4 -3 0 3 -3 0 6 -4 -3 -2 -1 1 1 0 0 0 0 0 0 0 0 0 0 32 0 0 54 0 0 0 0 0 14 0.65 0.21 87 S 1 -1 0 -1 -1 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.74 0.21 88 K -2 4 -1 -2 -4 1 0 -2 -1 -4 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 33 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0.79 0.21 89 W -3 -3 -4 -5 -3 -3 -4 -3 -3 -2 0 -4 -1 0 -4 -3 -3 11 1 -3 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 87 0 0 2.35 0.21 90 L -3 -3 -4 -4 -3 -3 -4 -4 -2 0 3 -4 1 6 -4 -3 -2 -1 1 -1 0 0 0 0 0 0 0 0 0 0 44 0 0 56 0 0 0 0 0 0 0.74 0.21 91 F -2 -3 -3 -4 -2 -3 -3 -4 -2 0 3 -3 0 6 -4 -1 -2 -1 1 -1 0 0 0 0 0 0 0 0 0 0 36 0 0 57 0 8 0 0 0 0 0.64 0.21 92 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.35 0.21 93 E 1 -1 -1 1 -4 1 6 -2 -1 -4 -3 0 -3 -4 -2 -1 -1 -4 -3 -3 14 0 0 0 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0.84 0.21 94 Q -1 1 -1 -1 -4 5 1 -2 -1 -3 -3 4 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 57 0 0 0 0 0 43 0 0 0 0 0 0 0 0 0.76 0.21 95 P 0 -2 -1 -2 -2 -1 -1 -2 -2 -3 -3 -1 -3 -4 6 3 0 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57 43 0 0 0 0 1.20 0.21 96 R -1 4 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 21 0 0 0 0 0 0 0 0 0 79 0 0 0 0 0 0 0 0 0.79 0.21 97 V -1 -3 -4 -4 -2 -3 -4 -4 -4 4 2 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 45 11 0 0 0 0 0 0 0 0 44 0.57 0.21 98 I -2 -4 -4 -4 -2 -3 -4 -4 -4 6 1 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 0 11 0.71 0.21 99 I -2 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 87 0 0 0 0 0 0 0 0 0 13 0.70 0.21 100 Q -1 0 -1 -1 -4 7 1 -2 0 -3 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.02 0.21 101 P -1 -3 -3 -2 -4 -2 -2 -3 -3 -3 -4 -2 -3 -4 8 -1 -2 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.29 0.21 102 G -1 -3 -2 -2 -3 -2 1 5 -3 -1 0 -2 -1 -3 -3 -1 -2 -3 -3 0 0 0 0 0 0 0 14 57 0 0 16 0 0 0 0 0 0 0 0 13 0.52 0.21 103 Q -1 2 2 -1 -3 3 2 1 -1 -3 -3 2 -2 -4 -2 0 1 -3 -3 -3 0 16 14 0 0 17 13 11 0 0 0 16 0 0 0 0 13 0 0 0 0.37 0.21 104 T 0 -1 2 -1 -2 -1 -1 -2 3 -3 -3 -1 -2 -3 3 3 2 -4 -2 -2 0 0 13 0 0 0 0 0 13 0 0 0 0 0 14 43 17 0 0 0 0.49 0.21 105 K -1 2 -1 0 -4 1 4 -3 -1 -4 -3 4 -2 -4 -2 -1 -1 -4 -3 -3 0 13 0 0 0 0 43 0 0 0 0 44 0 0 0 0 0 0 0 0 0.67 0.21 106 E 2 0 -1 0 -3 5 3 -2 -1 -3 -3 0 -2 -4 -2 0 -1 -3 -2 -2 25 0 0 0 0 43 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0.59 0.21 107 S 2 -1 0 -1 -1 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0.65 0.21 108 I -2 -3 -4 -4 -2 -3 -4 -4 -4 4 3 -3 1 0 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 57 43 0 0 0 0 0 0 0 0 0 0.61 0.21 109 D -2 0 0 5 -4 0 3 -2 -1 -3 -4 3 -3 -4 -2 -1 0 -4 -3 -3 0 0 0 43 0 0 23 0 0 0 0 26 0 0 0 0 8 0 0 0 0.63 0.21 110 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.76 0.21 111 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.70 0.21 112 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 1 0 -3 -2 -1 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0.65 0.21 113 K -1 1 -1 -1 -4 5 1 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 43 0 0 0 0 0 57 0 0 0 0 0 0 0 0 0.73 0.21 114 A 0 -3 -4 -4 -2 -3 -3 -4 -4 5 1 -3 0 -1 -3 -2 -1 -3 -2 3 9 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 21 0.56 0.21 115 A 4 -2 -2 -2 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 -2 1 3 -3 -2 -1 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33 0 0 0 0.53 0.21 116 A 5 -2 -2 -3 -1 -2 -2 -1 -2 -1 -2 -2 -1 -3 -2 0 -1 -3 -2 1 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0.57 0.21 117 D -1 -2 1 3 -2 -1 -1 2 -2 -2 0 -1 -2 -3 -2 3 -1 -4 -3 -2 0 0 8 21 0 0 0 21 0 0 14 0 0 0 0 36 0 0 0 0 0.35 0.21 118 F -3 -4 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 -1 7 -4 -3 -3 0 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.18 0.21 119 S -1 0 -1 0 -4 3 5 -2 -1 -4 -3 2 -2 -4 -2 1 -1 -3 -3 -3 0 0 0 0 0 13 57 0 0 0 0 13 0 0 0 17 0 0 0 0 0.64 0.21 120 S 0 -2 0 -1 -1 -1 -1 -2 -2 -2 -2 -1 -2 -3 -2 4 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44 56 0 0 0 0.61 0.21 121 P -1 0 -2 -1 -4 0 1 -3 -2 -3 -3 3 -3 -4 6 -1 -2 -4 -3 -3 0 0 0 0 0 0 9 0 0 0 0 35 0 0 57 0 0 0 0 0 1.19 0.21 122 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -1 -3 -2 -1 -4 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1 -2 -2 -2 -2 2 -4 -2 -2 1 8 -2 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87 0 1.08 0.21 132 E -2 -2 -1 2 -3 0 4 -3 -2 -1 2 -1 0 -2 -2 -2 -2 -3 -2 -1 0 0 0 13 0 0 46 0 0 0 40 0 0 0 0 0 0 0 0 0 0.43 0.20 133 V -2 0 -2 -2 -3 -1 -1 -3 3 0 2 3 0 -2 -2 -2 -1 -3 -1 1 0 0 0 0 0 0 0 0 14 0 28 40 0 0 0 0 0 0 0 18 0.28 0.20 134 G -1 -1 -1 -1 -3 2 3 2 -1 -2 -3 2 -2 -3 -2 1 -1 -3 -3 0 0 0 0 0 0 12 29 18 0 0 0 14 0 0 0 15 0 0 0 13 0.31 0.20 135 D -2 -2 1 6 -4 0 2 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 85 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.20 136 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.76 0.20 137 I -2 -1 -2 -1 -3 0 3 -3 -2 4 -1 3 -1 -2 -2 -2 -1 -3 -2 0 0 0 0 0 0 0 25 0 0 46 0 29 0 0 0 0 0 0 0 0 0.33 0.20 138 K 0 -1 2 2 -2 0 0 -1 -1 -3 -3 2 -2 -3 -2 4 0 -4 -3 -3 0 0 12 13 0 0 0 0 0 0 0 18 0 0 0 57 0 0 0 0 0.48 0.20 139 A 4 1 -2 -3 -2 1 -1 -1 -1 -2 -2 -1 -2 -1 -2 0 -1 5 2 -1 60 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 9 12 0 0.43 0.20 140 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -2 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.31 0.20 141 D -2 -1 2 5 -4 2 3 -2 -1 -4 -4 -1 -3 -4 -2 -1 -1 -4 -3 -4 0 0 12 56 0 14 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0.81 0.20 142 N 0 -1 5 0 -3 2 0 -1 4 -4 -4 -1 -2 -3 -2 0 -1 -4 -2 -3 13 0 59 0 0 15 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0.64 0.20 143 Q -1 0 0 0 -3 5 3 -2 0 -3 -3 1 -1 -3 -2 2 0 -3 -2 -3 0 0 0 0 0 56 23 0 0 0 0 0 0 0 0 21 0 0 0 0 0.59 0.12 144 K -1 1 0 -1 -4 1 0 -2 5 -3 -3 5 -2 -3 -2 -1 -1 -3 -1 -3 0 0 0 0 0 0 0 0 23 0 0 77 0 0 0 0 0 0 0 0 0.61 0.12 145 K -1 1 0 -1 -3 1 0 -2 -1 -3 -3 5 -2 -3 -1 2 0 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 79 0 0 0 21 0 0 0 0 0.55 0.12 146 L 2 -2 -3 -3 -1 -2 -3 -2 -3 1 4 -2 1 0 -3 -1 -1 -2 -2 0 28 0 0 0 0 0 0 0 0 0 72 0 0 0 0 0 0 0 0 0 0.35 0.09 147 I 2 -3 -3 -3 -1 -2 -3 -2 -3 3 2 -2 1 -1 -2 -1 -1 -3 -2 1 29 0 0 0 0 0 0 0 0 43 28 0 0 0 0 0 0 0 0 0 0.27 0.09 148 T 0 0 0 -1 -2 0 0 -1 -1 -2 -3 2 -2 -3 -1 3 2 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 51 22 0 0 0 0.38 0.09 149 I -1 -2 -2 -2 -1 -2 -2 -3 -3 3 0 -2 0 -1 -2 0 4 -3 -2 1 0 0 0 0 0 0 0 0 0 51 0 0 0 0 0 0 49 0 0 0 0.34 0.09 150 E -1 0 3 1 -4 1 5 -2 0 -4 -3 0 -2 -4 -2 0 -1 -3 -2 -3 0 0 22 0 0 0 78 0 0 0 0 0 0 0 0 0 0 0 0 0 0.71 0.09 151 R 2 3 -1 -1 -2 3 0 -1 -1 -3 -2 3 -1 -3 -2 0 -1 -3 -2 -2 28 22 0 0 0 29 0 0 0 0 0 22 0 0 0 0 0 0 0 0 0.39 0.09 152 N 0 -1 5 1 -2 0 0 -1 0 -3 -3 0 -2 -3 -2 3 0 -4 -2 -3 0 0 61 0 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 0 0.56 0.06 153 L -1 0 -1 -2 -2 0 -1 -2 -2 0 1 3 0 -2 -2 0 2 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 30 39 0 0 0 0 31 0 0 0 0.20 0.06 154 A 4 -2 -2 -2 -1 -1 -2 -1 -2 0 2 -1 0 -1 -2 0 -1 -3 -2 0 69 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0 0.28 0.06 155 L -2 -3 -3 -4 -2 -3 -3 -4 -2 0 2 -3 1 6 -4 -3 -2 0 2 0 0 0 0 0 0 0 0 0 0 0 30 0 0 70 0 0 0 0 0 0 0.60 0.06 156 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -1 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.53 0.01 157 A 3 -2 -1 -2 -1 -1 -2 4 -2 -2 -3 -1 -2 -3 -2 0 -1 -3 -3 -1 50 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0.53 0.01 K Lambda Standard Ungapped 0.1298 0.3132 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1555 0.3175 PSI Gapped 0.0476 0.2670