Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 P -4 -6 -6 -5 -6 -5 -5 -6 -6 -6 -7 -4 -6 -7 9 -4 -5 -7 -7 -6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 3.16 1.75 2 K -4 5 -2 -2 -5 3 4 -4 -3 -6 -6 4 -3 -7 -4 -2 -4 -7 -5 -5 1 28 1 1 0 14 29 1 0 0 0 19 1 0 0 2 1 0 0 0 1.07 2.06 3 V -2 -5 -5 -4 -3 -4 -6 -6 -3 4 4 -5 1 -3 -6 -5 -3 -6 -3 5 3 0 1 1 1 1 0 0 1 17 35 1 2 1 0 1 1 0 1 33 0.99 2.19 4 G -2 -2 4 3 -6 -3 -3 6 -2 -7 -7 -2 -6 -6 -2 -2 -4 -7 -6 -6 2 2 20 13 0 1 1 52 1 0 0 2 0 0 2 2 0 0 0 0 1.24 2.21 5 R -4 2 4 2 -2 0 1 3 0 -7 -6 2 -5 -6 -3 0 -2 -7 -5 -6 1 9 17 12 1 4 10 21 3 0 0 12 0 0 1 7 2 0 0 0 0.61 2.22 6 L -3 0 -1 -2 0 -1 -1 -5 1 1 1 3 1 2 -6 -2 -2 -4 2 2 1 6 3 2 2 3 4 0 3 6 13 20 3 7 0 2 3 0 6 16 0.34 2.22 7 I -2 -6 -7 -7 -4 -6 -7 -5 -5 5 4 -6 3 0 -7 -6 -4 -4 -2 3 3 0 0 0 0 0 0 1 0 34 36 0 6 3 0 0 0 0 1 15 1.12 2.22 8 Y -3 -5 -6 -6 -3 -5 -6 -6 -2 1 0 -6 -1 4 -7 -5 -5 1 8 2 2 0 0 0 1 0 0 0 1 6 10 0 1 14 0 1 0 1 49 13 1.48 2.23 9 T 2 -5 -5 -6 -1 -5 -5 -4 -5 3 1 -5 1 -1 -5 -2 -1 -5 -4 5 16 0 1 0 1 0 0 1 0 15 12 0 3 3 0 3 3 0 0 39 0.78 2.25 10 A 1 -6 -5 -6 1 -5 -5 1 -4 3 0 -6 1 4 -6 -3 -2 0 -2 3 10 0 0 0 2 0 0 11 0 18 10 0 3 18 0 2 3 1 1 20 0.60 2.24 11 G -2 -5 -3 -4 -4 -6 -5 8 -4 -7 -6 -5 -5 -6 -5 -3 -4 -6 -6 -6 2 0 1 1 0 0 0 90 0 0 1 0 0 0 0 1 1 0 0 0 2.16 2.25 12 G -3 -3 -3 -4 -4 -4 -4 7 -4 -6 -6 -4 -2 -5 -5 -3 -4 -3 -4 -6 1 2 1 1 0 1 1 86 0 0 1 1 1 0 0 2 1 0 1 0 1.97 2.25 13 Y -3 2 -1 -1 3 1 -1 -3 1 -1 -1 -1 1 2 -4 0 -1 4 5 -1 2 9 3 4 5 6 4 2 3 3 7 4 3 7 1 7 3 5 16 5 0.32 2.22 14 F -1 -2 3 4 0 -2 -2 1 0 -2 -3 -3 -1 0 -3 1 1 -3 0 -2 5 2 14 22 2 2 3 9 2 3 3 2 2 5 1 9 9 0 3 3 0.34 2.22 15 R -1 2 2 0 -4 0 0 3 0 -4 -3 1 -3 -2 0 1 0 -1 -2 -4 4 12 8 6 0 4 7 18 2 1 3 7 1 2 5 12 5 1 1 1 0.27 2.22 16 Q -2 1 2 2 -1 2 2 0 1 -4 -4 2 -2 -3 -2 1 -1 -3 -3 -3 4 8 9 11 2 9 11 8 4 1 1 11 1 2 2 9 4 0 1 2 0.28 2.24 17 S 1 0 1 0 3 -2 -1 0 0 -2 -4 -2 -3 -3 2 2 1 -1 0 -1 12 4 5 4 5 2 3 7 2 3 1 3 1 1 11 17 9 1 4 5 0.22 2.24 18 L -3 -3 -3 -3 0 -2 -3 -5 -1 1 4 -3 1 0 -4 1 2 -1 0 1 2 2 1 2 2 2 2 1 2 7 33 2 3 4 1 9 12 1 3 9 0.40 2.21 19 S 0 2 4 2 0 -1 -2 -2 -2 -4 -4 1 -3 -4 -1 3 0 -2 -3 -3 8 9 19 10 2 2 3 3 1 1 1 8 1 1 3 21 5 1 1 2 0.43 2.22 20 Y -1 0 0 3 1 -1 1 -3 1 -3 -3 -1 -1 -2 -4 3 2 -2 0 -2 4 5 4 14 3 3 8 1 3 2 3 4 2 2 1 23 11 1 4 3 0.32 2.22 21 L 0 -4 -4 -4 1 -5 -5 -4 -4 2 2 -5 2 1 -4 -3 0 0 -4 5 8 1 1 1 3 0 0 2 0 9 16 0 5 5 1 1 6 1 0 38 0.67 2.22 22 E -3 -2 -3 1 0 0 5 -5 3 -2 -1 -3 -1 1 -5 -2 -2 6 3 -3 2 2 1 9 2 4 31 1 6 2 6 1 1 6 0 3 2 10 8 2 0.66 2.22 23 A 1 2 -5 -4 5 -2 -2 -4 -2 1 0 0 1 -1 -5 -1 -2 2 -1 3 10 12 0 1 11 2 3 1 1 7 8 5 4 3 0 6 3 3 3 17 0.35 2.23 24 Y -5 -5 -5 -6 -4 -5 -5 -6 -2 -2 1 -5 -2 5 -6 -5 -4 3 9 -4 1 1 0 0 0 0 0 0 0 2 11 0 1 21 0 1 1 3 56 1 1.78 2.23 25 N -4 -3 4 7 0 -3 -1 -4 0 -5 -6 -3 -3 -4 -3 0 -3 -4 -4 -4 1 1 17 58 2 1 2 1 3 1 1 1 1 1 1 6 1 0 1 1 1.39 2.24 26 P -1 -4 -4 -3 2 -3 -3 -4 -2 0 0 -4 -1 0 6 -1 1 -3 -2 0 5 1 1 1 4 1 2 1 1 6 10 1 2 4 39 4 9 0 1 7 0.77 2.22 27 S 1 3 -1 0 -1 1 1 -2 -1 -1 -1 1 -2 0 -3 1 0 -2 -2 0 10 13 3 6 1 5 10 3 2 3 6 8 1 4 1 9 5 1 2 7 0.14 2.23 28 N 0 0 1 0 -2 0 0 -2 -1 -2 -2 0 -1 -3 -4 2 5 -3 -4 -3 8 6 6 4 1 4 6 3 2 2 4 6 1 1 1 14 29 0 1 2 0.39 2.24 29 G -3 0 5 3 -3 1 -1 2 2 -5 -2 1 -1 -3 -4 -2 -4 -2 -3 -5 2 5 25 16 1 6 4 14 5 0 4 7 2 1 1 3 1 1 1 1 0.58 2.23 30 T -1 3 -1 -2 0 2 1 -4 0 -2 -2 2 -2 -4 -4 1 3 -2 -1 -1 5 12 2 2 2 9 10 1 2 2 4 10 1 1 1 11 18 1 2 4 0.33 2.24 31 W -5 -4 -5 -6 -2 -4 -5 -6 -3 -4 -3 -5 -3 0 -6 -5 -5 13 -1 -4 1 1 1 0 1 1 0 0 1 1 2 0 0 3 0 1 1 84 1 1 3.64 2.24 32 L -2 2 -1 -3 -1 1 1 -3 2 0 -2 1 0 -1 -5 2 3 -1 0 -1 2 12 3 1 1 6 7 2 4 5 4 7 3 2 0 13 17 1 3 5 0.26 2.25 33 R -1 2 -1 -2 -3 2 1 -3 0 -2 -2 1 0 -2 2 0 1 -2 0 -1 6 9 3 3 1 9 10 2 2 2 5 9 3 2 10 8 10 1 3 4 0.18 2.26 34 L 0 -2 -5 -5 2 -3 -3 -1 -2 2 4 -1 1 -1 -4 -3 -1 -2 -3 3 7 3 0 0 4 1 2 6 1 9 32 4 3 2 1 2 3 1 1 18 0.42 2.26 35 A 3 -2 -2 -3 0 -1 -1 1 -3 -4 -4 -1 -3 -4 5 1 1 -7 -4 -3 22 2 2 1 2 2 3 10 1 1 1 3 1 1 24 11 9 0 1 1 0.56 2.26 36 D -1 -1 1 3 -1 0 1 -2 -1 -5 -5 0 -3 -5 4 3 -1 -3 -3 -4 4 3 7 15 1 3 8 3 2 1 1 5 1 1 19 19 4 1 1 1 0.50 2.26 37 L -2 -3 -3 -5 -1 -3 -4 -4 -3 1 3 -3 8 0 -1 -3 -2 -2 -2 -1 4 1 1 1 1 1 1 2 1 6 24 2 39 3 4 2 2 1 1 4 1.02 2.25 38 Q -3 0 2 -3 -2 1 -1 -3 2 -2 -2 -1 -2 -4 6 0 -1 -3 -4 -3 2 4 8 1 1 6 3 2 4 3 5 4 1 1 41 7 3 1 1 1 0.82 2.25 39 V -1 0 -1 -1 0 2 -1 -1 1 1 -1 -1 1 -1 -1 0 2 -1 0 1 5 5 2 3 2 8 5 5 3 6 5 4 3 3 4 8 13 1 4 11 0.09 2.25 40 P 2 1 -1 -2 1 -2 0 0 -1 -4 -4 0 -2 -3 5 -1 -2 -2 -3 -3 19 8 4 2 3 2 5 7 2 1 2 6 1 1 26 5 3 1 1 2 0.50 2.25 41 R -3 7 -3 -4 0 -2 -3 -5 0 -3 -1 0 0 -3 -3 -2 -3 -1 -3 -2 2 63 1 1 2 1 1 1 2 2 7 3 2 1 1 2 1 1 1 4 1.28 2.28 42 S 1 1 -1 -1 3 0 -1 -2 2 -2 -2 -1 0 0 -2 2 0 2 3 -1 9 7 3 3 5 4 4 4 4 2 3 4 2 4 2 15 5 3 9 5 0.13 2.28 43 G -1 1 1 0 1 -1 0 3 4 -3 -3 -1 0 1 -2 0 -3 1 2 -4 5 6 6 5 3 3 6 18 8 1 3 3 2 5 2 8 2 2 7 1 0.20 2.25 44 L 1 -2 -2 -3 3 -1 -3 -3 6 -1 -1 -3 0 3 1 -1 -2 0 1 -1 12 2 2 2 6 2 1 2 20 3 6 2 3 11 7 4 3 1 4 4 0.42 2.25 45 A 2 0 -1 -2 2 1 -2 1 -1 -2 -3 -1 0 -1 -2 2 1 2 -1 -2 17 4 2 2 4 5 2 12 2 2 2 3 2 2 2 16 7 3 2 3 0.19 2.23 46 G 2 -2 -1 -2 3 -1 -2 0 0 -1 -1 -2 1 0 -1 1 0 2 -1 1 18 2 3 2 5 3 2 6 2 4 7 3 4 3 3 10 5 2 2 8 0.09 2.20 47 C 2 -2 -1 -2 5 -1 -2 -1 0 0 -2 -5 0 0 -1 -1 1 2 -1 2 14 3 3 3 11 3 3 6 3 4 4 0 3 3 3 5 8 2 3 12 0.17 2.18 48 V 1 -2 -2 -3 1 -2 -1 -3 -1 0 0 -2 0 1 -2 -1 1 1 0 3 11 2 2 2 3 2 4 2 2 5 8 2 2 7 2 6 8 2 4 20 0.14 2.20 49 V -2 -2 -2 -2 2 -2 -3 -2 2 2 2 -2 2 0 -3 -2 -2 1 1 2 3 2 2 3 4 2 2 3 4 11 21 2 5 4 2 3 3 2 5 13 0.22 2.21 50 G -2 -1 3 4 -1 -1 0 3 1 -4 -4 0 -2 -3 -3 -1 -3 -1 -3 -4 3 3 13 21 1 3 5 24 3 1 2 5 1 1 2 5 1 1 1 1 0.49 2.23 51 G -3 -1 4 2 -2 -2 -1 5 1 -4 -5 -1 -3 -4 -3 -1 -2 -2 -3 -5 1 3 20 10 1 2 4 33 3 1 1 4 1 1 1 4 2 1 1 1 0.65 2.26 52 L -2 2 0 -1 1 1 0 -2 2 -2 -1 4 -1 0 -4 -1 -2 -1 2 -2 3 10 4 3 2 5 5 3 5 3 5 25 2 5 1 4 3 1 6 4 0.28 2.27 53 L -3 -5 -5 -5 -2 -4 -5 -4 -6 5 3 -6 2 1 -5 -4 -3 -2 -3 3 2 1 1 1 1 1 1 1 0 30 29 0 5 4 1 1 1 1 1 17 0.82 2.20 54 Y -4 -4 -4 -5 -2 -5 -6 -5 0 0 0 -5 -1 4 -6 -4 -4 1 8 -1 1 1 1 1 1 0 0 1 2 6 9 1 1 17 0 1 1 2 48 5 1.37 2.19 55 A 2 -4 -4 -5 -1 -5 -4 -4 -3 2 0 -4 0 -2 -6 -3 -2 -6 -3 6 15 1 1 1 2 0 1 2 1 11 9 1 2 1 0 2 2 0 1 46 0.81 2.18 56 V 0 -4 -4 -5 0 -4 -4 -4 -3 4 0 -4 1 4 -4 -2 -1 1 0 3 8 1 1 1 2 1 1 2 1 19 10 1 3 16 1 4 3 2 3 21 0.54 2.13 57 G -2 -4 -3 -3 -3 -4 -4 7 -3 -5 -5 -4 -4 -4 -4 -2 -2 -2 -2 -4 2 1 1 1 1 1 1 78 1 1 1 1 1 1 1 3 3 1 1 1 1.63 2.11 58 G -1 0 1 0 3 1 0 -1 2 0 -1 0 2 1 -5 0 0 -5 1 0 6 6 5 6 5 5 6 6 5 6 6 6 5 5 0 6 6 0 5 6 0.11 1.89 59 R -1 1 -1 -2 3 0 -1 -1 1 0 -1 -1 1 1 -1 -1 -1 2 4 -1 5 9 3 3 6 4 4 5 3 6 6 4 3 6 3 4 4 2 12 5 0.14 2.06 60 N -1 0 2 1 0 -1 -1 0 1 -1 -2 -2 -1 -1 -1 1 1 1 1 -2 5 6 11 8 2 3 3 8 3 3 5 3 2 2 4 11 8 2 5 3 0.08 2.05 61 N -2 1 2 1 -1 -1 0 1 0 -1 -2 0 -1 -1 -1 1 0 0 0 -1 4 7 8 8 1 3 5 12 3 3 5 6 2 3 3 9 7 1 4 4 0.05 2.03 62 S -1 -1 1 1 0 0 0 1 1 -1 -2 -1 -1 -1 -1 2 0 0 1 -1 4 4 6 9 2 3 5 11 3 3 4 5 2 3 3 16 5 1 4 4 0.08 2.03 63 P -1 0 0 1 0 -1 1 2 0 -2 -2 -1 0 -1 1 1 0 0 1 -1 5 5 4 7 2 3 7 13 2 3 4 5 2 3 6 10 6 1 4 4 0.04 2.00 64 D -2 -1 1 3 -1 0 1 1 0 -1 -2 0 -1 -1 0 0 -1 0 -1 -2 4 4 6 16 2 4 7 9 2 4 4 6 2 3 4 7 4 1 2 3 0.10 1.98 65 G -1 0 1 0 1 1 0 3 1 -2 -2 0 -1 0 -1 0 -1 1 0 -2 5 4 6 6 3 6 6 18 3 2 4 6 2 4 4 7 4 2 4 4 0.08 1.92 66 N -1 0 1 0 1 0 0 -1 1 -1 -1 0 0 0 0 0 0 3 1 -1 5 6 7 6 3 4 7 6 3 4 6 5 3 4 5 7 5 3 5 4 0.02 1.91 67 T -1 1 0 -1 -1 0 0 -1 -1 -1 -1 0 0 -1 -1 1 2 1 0 0 5 7 5 4 1 4 6 5 2 4 6 6 2 2 3 12 11 2 3 8 0.05 1.92 68 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 69 S -1 -1 -1 -1 1 -1 -1 -1 1 -1 2 -1 1 1 -1 0 0 2 1 0 4 3 3 4 3 3 4 5 3 4 20 3 3 5 3 9 7 2 4 6 0.06 2.23 70 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 71 A -1 0 1 2 2 0 0 -2 1 -1 -2 -1 1 -1 -1 1 1 2 0 -1 6 5 7 9 4 4 6 3 3 3 4 4 3 3 3 12 9 3 3 5 0.11 2.17 72 L 0 -3 -2 -3 2 -2 -3 -1 -1 1 1 -3 2 1 -2 -2 -1 1 -1 4 7 2 2 2 4 2 2 5 2 7 14 2 5 6 2 2 4 2 2 27 0.31 2.16 73 D -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 74 C -1 2 -1 -2 5 0 -1 -2 0 1 -1 0 1 0 -2 -1 -1 2 0 1 5 11 3 3 9 4 5 3 3 8 6 5 3 3 3 6 4 2 3 11 0.16 2.14 75 Y -3 -3 -2 -2 0 -2 -2 -3 0 -2 1 -2 0 4 -2 -2 -2 2 7 -2 2 2 2 2 2 2 2 2 2 3 12 2 2 17 2 3 2 3 32 3 0.78 2.15 76 N -3 -2 4 6 -1 -1 -1 -2 0 -3 -3 -2 -2 -2 -3 1 -1 0 -2 -3 2 2 16 36 2 2 3 2 2 2 3 3 1 2 2 12 3 1 2 2 0.66 2.18 77 P -1 -2 -2 -3 -1 -1 -2 -3 0 0 1 -3 0 0 5 0 1 2 -2 0 5 2 2 1 2 3 2 2 2 5 12 1 2 3 29 6 7 2 1 6 0.43 2.19 78 M 0 2 0 1 -1 0 1 -1 0 -1 -1 1 0 -2 -2 1 0 -1 -2 -1 8 9 4 7 1 4 10 5 2 3 7 9 2 2 2 9 5 1 2 5 0.06 2.17 79 T -1 -1 0 0 -1 0 0 -2 0 -2 -1 0 -1 -2 -2 1 4 4 -2 -2 5 4 5 5 1 4 6 3 2 2 5 6 1 2 2 11 24 5 2 2 0.27 2.18 80 N -2 0 4 3 -2 0 -1 1 1 -4 -2 0 0 -1 -1 -1 -3 2 0 -4 3 6 19 14 1 4 4 10 4 1 4 6 2 3 3 5 1 2 3 1 0.30 2.19 81 Q -1 2 -1 -2 1 2 1 -3 0 -2 -3 1 0 -4 -3 1 3 0 -2 -1 5 10 2 2 3 9 9 2 2 3 2 10 2 1 1 12 15 1 1 4 0.23 2.25 82 W -4 -4 -4 -5 -2 -3 -5 -4 -2 -4 -3 -5 -3 0 -3 -4 -4 13 -1 -4 1 1 1 1 1 1 1 1 1 1 2 1 1 3 2 1 1 75 1 1 3.09 2.26 83 S -2 1 0 -1 -1 1 1 -3 1 0 -2 1 0 -2 -3 1 2 1 -1 0 3 9 4 3 2 6 9 2 3 5 4 8 2 2 2 12 14 2 2 6 0.13 2.26 84 P -1 0 0 -1 0 1 1 -3 0 -1 -1 1 0 -1 2 0 0 0 -1 -1 5 6 4 3 2 7 10 3 2 3 6 8 3 3 10 7 7 1 2 4 0.07 2.26 85 C 0 -1 -4 -4 2 -3 -3 -1 -2 2 2 -1 3 -2 -3 -2 0 -2 -3 3 6 4 1 1 4 1 2 6 1 12 17 4 7 1 1 3 5 1 1 19 0.29 2.25 86 A 3 -2 -1 -2 0 -1 -1 1 -2 -3 -4 -2 -3 -4 4 1 0 -3 -3 -1 24 2 3 2 2 3 4 11 1 2 2 3 1 1 17 10 5 0 1 4 0.36 2.25 87 P -1 -1 1 2 0 -1 0 -2 -2 -4 -4 -2 -3 -4 5 2 -1 -3 -3 -3 4 3 6 11 2 3 6 3 1 1 1 3 1 1 30 15 4 1 1 2 0.58 2.24 88 M -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 89 S -1 -1 0 -1 1 0 -1 0 1 -1 -2 -1 1 -1 5 -1 -1 2 -1 -2 4 4 5 3 3 3 3 6 3 4 5 4 3 3 24 5 4 3 3 3 0.26 2.24 90 V -1 1 -1 -1 1 1 0 0 1 -1 -2 0 0 0 1 0 1 1 0 0 6 6 3 4 3 6 6 6 4 4 4 5 3 3 6 6 8 2 4 6 0.01 2.24 91 P 1 1 -1 -2 1 -1 0 0 0 -3 -3 0 -1 -2 4 0 -1 0 -1 -2 10 7 3 3 3 3 6 8 2 2 3 6 2 2 20 6 3 1 2 3 0.21 2.25 92 R -1 6 -1 -2 1 -1 -2 -2 1 -2 -2 0 0 -2 0 -1 -2 1 -1 -1 4 37 2 3 3 2 2 4 3 3 5 4 3 2 4 4 3 2 2 4 0.47 2.25 93 N 1 1 0 -1 3 -1 -1 0 2 -2 -3 -1 0 0 -2 2 -1 2 2 -2 9 7 4 4 5 3 5 6 5 2 3 3 2 4 2 13 4 3 8 3 0.11 2.25 94 R -1 2 1 -1 1 -1 -1 2 3 -2 -2 -1 -1 0 -1 1 -1 1 1 -2 6 10 6 4 3 3 3 14 6 2 4 3 2 4 3 9 3 2 5 3 0.10 2.24 95 I 0 -2 -2 -2 3 -2 -2 -1 6 -1 0 -2 1 3 0 0 -1 0 0 0 7 2 2 2 5 2 2 5 15 3 8 2 3 10 5 6 5 1 3 6 0.23 2.24 96 G 2 -1 -1 -1 2 -1 -2 3 0 -2 -4 -1 -1 -2 -2 2 0 -1 -2 -2 18 3 2 3 4 3 2 19 3 2 2 4 2 2 2 13 6 1 2 4 0.22 2.24 97 V 2 -1 -3 -3 3 -2 -3 0 2 -1 0 -3 2 -1 -1 1 0 -1 -1 2 16 3 1 1 5 1 1 7 4 4 10 1 5 2 3 9 5 1 2 13 0.16 2.24 98 G 3 -3 -2 -2 4 -3 -3 0 -2 0 -1 -4 -2 -2 -3 -1 1 -1 -3 3 24 2 2 2 8 1 1 8 1 4 5 1 1 2 1 5 9 1 1 20 0.37 2.24 99 V 2 -3 -3 -3 1 -2 -1 -2 -1 0 0 -3 0 0 -1 0 0 -1 -1 4 16 2 1 1 3 2 4 3 2 4 8 1 2 4 3 7 6 1 2 27 0.27 2.24 100 I -1 -1 -2 -2 2 -2 -3 -2 2 1 2 -2 2 1 -1 -2 -1 3 2 1 6 3 2 3 4 2 2 3 5 7 18 2 5 5 3 3 3 3 6 11 0.17 2.24 101 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 102 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 103 H -1 1 0 -1 2 0 -1 -1 2 -1 -2 3 0 0 -1 0 -1 2 1 -2 4 9 4 4 4 4 4 4 5 4 5 15 3 4 3 6 4 3 5 4 0.09 2.23 104 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 105 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 106 A 0 -2 0 -1 1 -1 -2 -2 2 1 0 -1 0 0 -1 -2 -1 2 1 3 8 3 4 4 3 3 3 4 4 8 8 4 3 3 3 4 4 2 5 16 0.07 2.23 107 V -1 -2 0 -1 1 -1 -3 0 1 1 -1 -1 1 2 -1 -1 -1 4 1 1 6 3 5 4 3 3 2 7 4 9 6 4 4 8 3 4 5 5 4 9 0.07 2.23 108 G -1 -1 0 -1 1 0 0 4 1 -1 -2 -1 0 -1 -2 -1 -1 2 0 -1 5 3 4 4 3 4 5 29 3 3 4 3 2 3 3 4 4 2 3 4 0.22 2.23 109 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 110 S -1 0 0 0 1 0 0 1 1 -1 -2 0 0 0 -1 0 0 3 1 -2 5 6 4 5 3 4 7 12 3 3 4 6 3 4 3 7 6 3 5 3 0.03 2.23 111 H -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 112 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 113 C -1 0 1 1 2 0 -1 0 1 -1 -2 -1 1 0 -1 0 0 3 1 -1 5 5 6 7 3 4 5 8 4 3 5 5 3 4 4 7 5 3 5 4 0.01 2.23 114 I -1 1 0 0 0 0 0 1 0 -1 -1 0 0 0 -2 1 1 1 0 0 4 7 4 5 2 4 6 10 2 4 5 5 3 4 3 9 8 2 4 6 -0.01 2.22 115 H -1 1 0 0 2 -1 -1 -1 1 0 -2 -1 0 1 0 0 -1 2 3 0 6 7 5 4 4 3 4 5 4 5 5 4 2 5 5 7 4 2 9 6 0.04 2.21 116 H -2 -1 -1 -1 1 -1 -1 -1 1 -1 2 -1 1 1 -1 0 0 1 1 0 3 4 4 3 3 3 4 5 4 4 20 3 4 6 3 6 6 2 4 6 0.06 2.21 117 N -1 0 4 2 -1 -1 -2 -1 -1 -2 -3 1 -1 -2 -1 1 -1 0 -1 -2 6 5 21 10 2 3 3 5 1 2 3 7 1 2 4 11 4 1 2 3 0.24 2.21 118 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 119 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 120 E -2 -1 -1 0 1 0 2 -1 2 -1 -1 -1 1 0 -1 -1 -1 4 2 -1 4 4 4 5 3 5 13 5 4 4 5 4 3 4 3 4 4 5 7 4 0.09 2.23 121 R -1 1 -1 -1 3 0 0 -2 1 0 -1 -1 1 0 -2 -1 -1 2 1 1 6 8 3 3 6 4 6 3 3 6 5 4 3 4 3 6 4 3 5 10 0.04 2.23 122 Y -2 -2 -1 -1 0 -1 -2 -4 0 -1 -1 -2 0 3 -1 -2 -1 4 6 -2 3 3 4 4 2 2 3 2 2 3 7 3 2 12 3 4 3 5 24 3 0.44 2.23 123 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 124 P -2 -1 0 0 1 -1 -1 -2 1 0 -1 -1 0 0 4 -1 -1 3 0 -1 4 4 4 4 3 3 5 3 3 5 6 4 3 4 20 5 5 3 4 4 0.18 2.24 125 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 126 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 127 D -2 0 3 2 1 1 -1 0 1 -1 -2 0 1 -1 -1 -1 -1 3 0 -2 4 5 13 11 3 5 5 7 3 3 4 5 3 3 3 4 4 4 3 3 0.09 2.23 128 E -1 1 0 -1 1 1 1 -2 0 -1 -2 1 1 0 -2 0 1 3 0 -1 4 7 4 4 3 7 7 3 3 4 4 9 3 3 3 7 10 4 3 5 0.05 2.23 129 W -2 -1 -1 -1 0 -2 -2 -2 0 -2 -2 -2 0 -1 -1 -2 -1 11 0 -2 3 3 3 3 2 2 3 4 2 3 3 3 2 3 3 3 4 40 3 3 1.22 2.23 130 H -1 1 0 -1 1 0 1 -1 1 -1 -1 -1 1 -1 -1 1 2 4 -1 -1 4 6 4 3 2 5 8 4 3 4 5 4 3 3 3 9 11 4 3 5 0.04 2.22 131 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 132 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 133 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 134 P -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 135 M -1 0 0 -1 1 -1 -1 -1 1 0 0 -1 4 0 0 -1 -1 3 1 -1 5 4 4 4 3 3 4 4 3 5 9 4 11 4 6 5 4 3 4 5 0.08 2.22 136 L -2 0 1 -1 1 0 -1 0 1 -1 -2 -1 1 0 3 0 -1 2 -1 -2 4 4 5 4 3 4 4 7 3 4 5 4 4 3 16 8 5 3 3 4 0.11 2.22 137 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 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3 3 5 3 3 4 8 7 3 3 3 0.04 2.22 255 T -2 0 0 1 0 0 1 0 0 -2 -3 1 0 -2 -1 1 2 0 -1 -1 4 5 5 6 2 5 9 6 3 3 3 7 3 2 3 9 13 1 2 5 0.07 2.25 256 F -1 0 0 0 2 -2 -1 -2 1 0 -1 -2 0 2 0 -1 0 1 3 0 6 6 5 5 5 2 5 3 3 5 6 2 2 8 4 6 6 2 9 7 0.06 2.22 257 L -2 -2 -2 -3 0 -2 -3 -3 1 0 4 -2 1 1 -2 0 1 -1 0 1 3 3 2 1 2 2 2 2 3 5 32 3 4 6 2 7 9 1 3 8 0.30 2.24 258 D -1 0 4 3 -2 -1 -2 -1 -1 -4 -3 0 -2 -2 -2 2 0 -1 -2 -3 6 4 19 17 1 2 3 5 2 1 3 7 1 2 3 14 5 1 2 2 0.37 2.26 259 S -1 -2 1 3 1 -1 1 -3 0 -2 -3 -2 -2 -3 -3 3 3 0 -2 -2 5 2 7 17 3 2 8 1 2 2 3 2 1 1 1 22 15 2 2 2 0.42 2.25 260 V 0 -6 -4 -5 0 -4 -4 -2 -3 3 1 -4 3 0 -3 -3 0 -1 -3 5 8 0 1 1 2 1 1 4 1 12 10 1 6 4 1 2 6 1 1 39 0.66 2.24 261 E -3 -2 -3 0 -2 1 6 -4 3 -3 -2 -3 -2 -1 -5 -3 -3 5 2 -3 3 2 1 4 1 6 46 1 6 2 5 1 1 3 0 1 1 7 6 2 0.89 2.22 262 C 0 2 -4 -4 5 -1 0 -4 -3 1 -1 0 1 -1 -4 0 -2 -2 -1 3 9 9 1 1 12 3 6 2 1 9 5 5 3 2 1 7 3 1 3 19 0.36 2.22 263 Y -5 -4 -5 -5 -3 -4 -5 -7 -1 -3 0 -6 -2 5 -5 -4 -5 2 9 -4 1 1 1 1 1 1 1 0 1 1 9 0 1 20 1 1 0 3 58 1 1.83 2.21 264 D -4 -2 4 7 2 -2 -1 -4 0 -4 -5 -3 -4 -4 -4 -1 -3 -3 -3 -4 1 2 17 55 4 1 3 1 2 1 1 1 0 1 1 5 2 1 1 1 1.28 2.21 265 P -2 -3 -4 -3 1 -3 -2 -3 -3 1 0 -3 -1 -2 7 -2 0 -1 -4 0 3 2 1 2 3 1 3 2 1 8 10 1 2 2 46 2 5 1 1 6 0.94 2.20 266 D 1 1 0 2 -2 0 3 -1 -1 -1 -3 1 -3 -3 -3 1 0 -2 -3 -1 10 7 4 10 1 4 20 4 1 3 3 8 1 1 1 9 5 1 1 5 0.24 2.21 267 T 0 1 0 -1 -2 0 0 -2 -2 -3 -1 1 -2 -3 -3 1 5 -2 -4 -3 7 6 4 3 1 3 5 3 1 2 6 8 1 1 2 12 35 1 1 1 0.47 2.20 268 D -4 0 5 5 -2 1 -1 2 -2 -5 -3 0 -1 -3 -3 -2 -3 0 -3 -5 1 5 23 27 1 6 3 13 1 0 3 6 2 1 2 3 1 1 1 1 0.70 2.20 269 T 0 2 -2 -3 1 2 2 -3 -1 -3 -3 2 -2 -4 -5 1 4 -3 -4 -1 6 11 2 1 3 8 11 2 2 2 2 11 1 1 0 10 21 0 1 5 0.38 2.21 270 W -5 -6 -6 -6 -3 -4 -6 -6 -6 -4 -4 -5 -3 -1 -7 -6 -5 13 -1 -4 0 0 0 0 1 1 0 0 0 1 1 1 0 2 0 0 0 89 1 1 3.95 2.20 271 S -2 1 0 -2 -1 0 2 -4 -1 -1 -3 1 -1 -3 -3 2 4 -4 -1 -2 3 8 4 2 2 4 13 1 2 4 2 7 1 1 1 16 22 0 3 3 0.36 2.20 272 E -1 1 -2 -1 -1 1 2 -3 0 -1 0 1 1 0 1 0 1 -3 -2 0 5 7 2 3 2 7 14 2 2 4 8 7 3 4 7 7 8 0 2 7 0.12 2.20 273 V -1 -2 -5 -4 0 -2 -2 -1 -1 3 2 -2 2 -1 -5 -3 -2 -1 -2 4 6 3 0 1 2 2 3 6 1 15 21 2 5 3 1 2 3 1 1 24 0.41 2.20 274 T 3 -2 -2 -2 1 0 -1 2 -2 -4 -3 -1 -4 -4 4 1 1 0 -4 -3 19 2 1 2 3 3 5 13 1 1 2 4 0 1 18 12 10 1 0 2 0.41 2.19 275 R -1 0 2 2 -1 0 0 -2 -1 -4 -4 -1 -3 -4 4 2 1 -4 -3 -3 6 6 10 10 1 3 6 3 2 1 2 4 1 1 21 16 7 0 1 1 0.44 2.20 276 M -3 -2 -3 -5 -2 -3 -3 -5 -4 0 4 -1 8 0 -1 -3 -3 -4 -3 -1 2 2 1 0 1 1 2 1 0 5 34 3 33 4 3 2 1 0 1 3 1.02 2.20 277 T -2 -1 2 -3 -2 -2 -2 -2 -1 -2 -2 -1 -3 -3 7 0 0 -4 -5 -3 3 3 9 1 1 2 2 3 2 3 4 4 1 1 48 8 5 0 0 2 1.01 2.21 278 S -1 1 -1 -2 1 1 1 -3 1 0 -2 0 -1 0 -1 2 2 -1 0 0 5 9 3 2 2 5 9 2 3 6 4 5 2 4 3 14 13 1 3 7 0.14 2.21 279 G 2 0 -2 -2 1 -3 -2 3 -1 -4 -4 -1 -3 -3 5 0 -2 -4 -1 -3 14 5 2 2 3 1 3 19 2 1 1 4 1 1 26 8 3 0 2 2 0.56 2.21 280 R -2 7 -3 -5 -3 -2 -3 -5 -1 -2 0 0 -1 -3 -4 -2 -2 2 -3 -1 3 58 1 0 1 1 1 1 2 3 9 3 2 1 1 3 3 3 1 4 1.12 2.22 281 S 1 0 0 -3 4 -2 -2 -1 2 -4 -2 -3 -3 2 -3 3 0 0 2 -2 12 5 4 2 7 1 2 5 5 1 3 1 1 8 1 24 4 1 7 2 0.35 2.22 282 G 0 0 1 0 0 -2 -1 4 0 -4 -4 -3 -3 0 -5 1 -3 1 3 -3 8 5 6 5 2 1 3 32 2 1 2 1 1 4 0 11 1 2 9 2 0.48 2.22 283 V 1 -4 -4 -5 3 -2 -4 -2 7 -1 0 -5 1 2 0 -2 -2 -2 0 1 14 1 0 1 5 1 1 3 25 3 9 0 3 9 4 3 3 1 3 9 0.64 2.21 284 G 3 -3 -1 -3 3 -1 -4 4 -2 -5 -5 -3 -3 -5 -2 3 0 -4 -4 -3 21 2 2 1 5 3 1 30 1 1 1 1 1 1 2 21 5 0 1 2 0.68 2.21 285 V 4 -5 -5 -6 6 -5 -5 -2 -1 0 -1 -5 2 -2 -5 0 -1 -6 -4 3 27 0 0 0 16 0 0 3 2 4 7 0 4 2 0 7 3 0 1 23 0.75 2.20 286 A 5 -5 -5 -5 6 -4 -4 -1 -4 -2 -4 -5 -3 -4 -5 -1 2 -7 -5 3 38 0 0 0 14 1 1 5 0 1 1 0 0 1 0 3 11 0 0 22 0.93 2.22 287 V 0 -6 -6 -7 -1 -5 -6 -7 -7 3 -1 -5 1 -2 -6 -4 -1 -7 -5 7 7 0 0 0 2 0 0 0 0 11 3 0 3 1 0 1 3 0 0 69 1.43 2.18 288 T -4 -6 -5 -6 -5 -5 -6 -6 -6 -2 -3 -5 -3 -5 -6 1 4 -7 -5 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 26 0 0 65 1.52 2.10 K Lambda Standard Ungapped 0.1374 0.3194 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.0928 0.3174 PSI Gapped 0.0284 0.2670