Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -2 -3 -2 -1 -2 -3 -2 1 2 -2 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.44 0.04 2 A 4 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.05 3 S 2 -1 0 -1 -2 -1 -1 -1 4 -3 -3 -1 -2 -3 3 3 0 -3 -1 -2 24 0 0 0 0 0 0 0 19 0 0 0 0 0 18 39 0 0 0 0 0.43 0.08 4 E -1 2 2 1 -4 1 4 1 0 -4 -3 0 -2 -4 -2 0 -1 -3 -2 -3 0 13 19 0 0 0 56 12 0 0 0 0 0 0 0 0 0 0 0 0 0.52 0.11 5 E -1 0 -1 1 -3 3 5 -2 -1 -3 -3 1 -2 -4 -2 0 1 -3 -2 -2 0 0 0 0 0 16 64 0 0 0 0 9 0 0 0 0 11 0 0 0 0.62 0.12 6 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.66 0.14 7 Q -1 2 -1 -1 -3 5 2 -3 0 -2 0 1 -1 -3 -2 -1 -1 -3 -2 -2 0 17 0 0 0 59 12 0 0 0 13 0 0 0 0 0 0 0 0 0 0.53 0.14 8 K -1 2 1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 0 8 0 0 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 0.67 0.14 9 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -1 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.17 0.14 10 L -2 -2 -3 -3 -2 1 -2 -4 -3 1 4 -2 1 0 -3 -2 -2 -2 -2 0 0 0 0 0 0 14 0 0 0 0 86 0 0 0 0 0 0 0 0 0 0.49 0.14 11 E -1 -1 -1 1 -4 2 6 -3 -1 -4 -3 0 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.94 0.14 12 E -1 0 -1 1 -3 1 5 -2 0 -3 -3 0 -2 -3 -1 0 -1 -3 -2 -2 1 1 0 1 0 0 90 1 0 1 1 1 0 0 1 1 1 0 0 1 0.79 0.12 13 V -1 -3 -3 -4 -1 -3 -3 -4 -4 2 1 -3 1 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 89 0.52 0.14 14 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.74 0.14 15 V 1 -2 -2 1 -2 0 3 -2 -2 0 -1 -1 1 -2 -2 -1 -1 -3 -2 3 13 0 0 8 0 0 32 0 0 0 0 0 8 0 0 0 0 0 0 38 0.25 0.16 16 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 4 -3 1 0 2 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 9 81 0 0 0 10 0 0 0 0 0 0.56 0.16 17 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 3 0 -3 -3 -1 -2 -2 2 0 0 0 0 0 0 0 0 0 0 75 0 12 0 0 0 0 0 0 13 0.56 0.16 18 E -1 -1 -1 0 -3 0 4 3 -1 -2 -3 1 -2 -3 -2 -1 -1 -3 -3 0 0 0 0 0 0 0 46 29 0 0 0 12 0 0 0 0 0 0 0 13 0.43 0.16 19 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.78 0.16 20 A 4 -2 -2 -2 -1 -1 -2 -1 -2 -1 -2 -1 -1 -3 -1 0 1 -3 -2 1 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 13 0.47 0.16 21 T 0 -2 0 -2 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -2 1 6 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.74 0.16 22 R -2 6 -1 -2 -4 1 0 -3 -1 -4 -3 3 -2 -3 -2 -1 -2 -3 -2 -3 0 87 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0.93 0.16 23 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.78 0.16 24 R -2 6 -1 -2 -4 0 -1 -3 -1 -4 -3 3 -2 -4 -3 -1 -2 -3 -2 -3 0 89 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 0 0 1.03 0.22 25 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 1 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 4 9 0 0 0 0 0 0 0 0 88 0.63 0.22 26 R -2 6 -1 -2 -4 0 -1 -3 4 -4 -3 1 -2 -2 -3 0 -2 -2 1 -3 0 68 0 0 0 0 0 0 18 0 0 0 0 0 0 6 0 0 8 0 0.76 0.22 27 D -2 -2 2 6 -4 -1 1 0 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 7 86 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 1.10 0.22 28 A 4 -2 -3 -3 -1 -2 -2 -1 -3 1 -1 -2 -1 -2 1 0 -1 -3 -2 2 64 0 0 0 0 0 0 0 0 8 0 0 0 0 6 0 0 0 0 22 0.43 0.22 29 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 5 -3 1 2 -4 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 93 0 0 7 0 0 0 0 0 0 0.71 0.22 30 T -1 -2 -1 -2 -2 -2 -2 -3 -3 1 0 -2 -1 -2 -2 0 5 -3 -2 0 0 0 0 0 0 0 0 0 0 11 9 0 0 0 0 0 80 0 0 0 0.59 0.22 31 A 4 -2 -2 -2 -1 -2 -2 -1 -2 0 -2 -1 -1 -3 -2 1 1 -3 -2 0 78 0 0 0 0 0 0 0 0 7 0 0 0 0 0 3 9 0 0 3 0.51 0.22 32 E -1 0 -1 1 -4 1 6 -3 -1 -4 -4 2 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 0 89 0 0 0 0 11 0 0 0 0 0 0 0 0 0.94 0.22 33 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 5 0 0 0 0 0 0 0 0 0 95 0 0 0 0 0 0 0 0 0.85 0.22 34 S 1 -2 -1 -2 1 -1 -1 -2 2 -3 -3 -1 -2 0 3 3 0 -2 1 -2 6 0 0 0 4 0 0 0 9 0 0 0 0 5 18 50 0 0 8 0 0.45 0.22 35 K -1 2 2 -1 -4 1 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -4 -3 -3 0 4 11 0 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 0.75 0.22 36 I -2 -3 -4 -4 -2 -3 -4 -4 -4 5 3 -3 1 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 73 27 0 0 0 0 0 0 0 0 0 0.65 0.22 37 E -1 -1 -1 1 -4 1 6 -3 -1 -4 -4 1 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 0 94 0 0 0 0 6 0 0 0 0 0 0 0 0 0.99 0.22 38 T 0 -2 -1 -2 -2 -1 -2 -2 -2 -1 0 -1 2 -2 -2 0 5 -3 -2 -1 4 0 0 0 0 0 0 0 0 0 9 0 8 0 0 0 79 0 0 0 0.59 0.22 39 E -1 -1 -1 1 -4 1 6 -3 -1 -4 -4 0 -3 -4 2 -1 -2 -4 -3 -3 0 0 0 0 0 0 89 0 0 0 0 0 0 0 11 0 0 0 0 0 0.96 0.22 40 I -2 -4 -4 -4 -2 -3 -4 -4 -4 6 1 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 10 0.73 0.22 41 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 6 0 0 0 0 0 0 0 0 0 94 0 0 0 0 0 0 0 0 0.84 0.22 42 N -2 -1 7 1 -3 -1 -1 -1 3 -4 -4 -1 -3 -3 -3 0 -1 -4 -2 -4 0 0 89 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 1.02 0.22 43 K -1 2 -1 -1 -4 3 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 14 0 0 0 0 0 86 0 0 0 0 0 0 0 0 0.75 0.19 44 M -1 -2 -2 -3 -2 -1 -2 -3 -2 1 1 -2 6 -1 -3 -1 1 -2 -2 2 0 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 16 0 0 14 0.48 0.15 45 Q -1 1 0 -1 -4 6 2 -2 0 -3 -3 2 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 80 4 0 0 0 0 16 0 0 0 0 0 0 0 0 0.78 0.15 46 Q -1 1 0 -1 -3 6 2 -2 0 -3 -3 1 -1 -4 -2 -1 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.15 47 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -1 -1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.77 0.15 K Lambda Standard Ungapped 0.1187 0.3028 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1536 0.3185 PSI Gapped 0.0470 0.2670