Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 R -2 6 -1 -2 -4 1 0 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.94 0.10 2 C -1 -4 -3 -4 10 -4 -4 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.79 0.21 3 H -2 -1 0 -2 -4 0 -1 -3 9 -4 -4 -1 -2 -2 -3 -2 -2 -3 1 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 1.41 0.21 4 E -2 -2 0 6 -4 0 4 -2 -1 -4 -4 -1 -3 -4 -2 -1 -2 -4 -3 -4 0 0 0 59 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0.96 0.21 5 G 0 -2 3 -1 -3 -2 -2 5 -2 -4 -4 -1 -3 -4 -2 2 -1 -4 -3 -3 0 0 25 0 0 0 0 53 0 0 0 0 0 0 0 22 0 0 0 0 0.73 0.21 6 G -1 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.42 0.26 7 Q -1 2 3 -2 -3 2 -1 -3 0 0 0 0 -1 -3 -3 -1 -1 -4 -2 2 4 17 18 0 0 13 0 0 2 4 6 3 0 0 0 3 0 0 0 30 0.23 0.26 8 S -1 -1 5 0 -2 -1 -1 -1 -1 -3 -2 -1 3 -3 -2 4 0 -4 -3 -2 0 0 40 0 0 0 0 0 0 0 0 0 13 0 0 47 0 0 0 0 0.57 0.26 9 Y -3 -2 -3 -4 -3 -2 -3 -4 2 -2 -2 -3 -2 2 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 4 0 0 0 0 0 0 0 0 0 96 0 1.36 0.26 10 K -2 5 -1 -2 -4 1 0 -3 -1 -4 -3 5 -2 -4 -2 -1 -2 -4 -3 -3 0 43 0 0 0 0 0 0 0 0 0 57 0 0 0 0 0 0 0 0 0.86 0.26 11 I -2 -4 -4 -4 -2 -4 -4 -5 -4 5 1 -3 0 -1 -4 -3 -1 -4 -2 3 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 25 0.73 0.26 12 G -1 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.42 0.26 13 D -2 -1 0 5 -4 1 5 -3 -1 -3 -3 -1 -3 -4 -2 -1 -2 -4 -3 -1 0 0 0 38 0 4 50 0 0 0 0 0 0 0 0 0 0 0 0 8 0.77 0.26 14 T -1 1 -1 -2 -3 2 0 -2 -2 -3 -3 4 -2 -4 -2 0 3 -3 -3 -2 0 4 0 0 0 13 0 0 0 0 0 46 0 0 0 0 37 0 0 0 0.54 0.26 15 W -3 -4 -5 -5 -3 -3 -4 -3 -3 -2 -2 -4 -2 0 -4 -4 -3 12 1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92 0 8 2.60 0.26 16 R -2 3 0 5 -4 1 1 -2 -1 -4 -4 1 -3 -4 -2 -1 0 -4 -3 -3 0 23 0 49 0 8 7 0 0 0 0 7 0 0 0 0 7 0 0 0 0.66 0.26 17 R -2 6 -1 -2 -4 0 -1 -3 1 -4 -3 3 -2 -4 -3 -1 -2 -4 -2 -3 0 79 0 0 0 0 0 0 4 0 0 18 0 0 0 0 0 0 0 0 0.99 0.26 18 P -1 2 -2 -2 -4 4 0 -3 -2 -3 -2 0 -2 -4 6 0 -1 -4 -3 -2 0 16 0 0 0 32 0 0 0 0 3 0 0 0 41 6 0 0 0 3 0.87 0.26 19 H 0 -1 0 -2 -3 -1 0 3 8 -4 -3 -1 -2 -2 -2 -1 -2 -3 0 -3 10 0 0 0 0 0 4 23 58 0 1 0 0 0 0 0 0 0 0 0 0.80 0.24 20 E -2 -1 -1 3 -4 1 6 -3 -1 -4 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 20 0 0 74 0 0 0 0 0 0 0 0 6 0 0 0 0 0.90 0.26 21 T -1 -1 4 0 -2 2 -1 -2 -1 -3 -3 0 -2 -3 -2 2 3 -3 -2 -2 0 0 36 0 0 13 0 0 0 0 0 4 0 0 0 15 28 0 0 0 0.49 0.24 22 G 0 -1 1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 5 4 6 0 0 0 0 85 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.26 23 G 0 1 0 2 -2 1 1 3 -1 -2 -2 0 -1 -2 -1 0 -1 -2 -1 -2 7 8 2 16 1 6 7 23 1 2 4 2 1 2 2 8 3 1 1 3 0.18 0.14 24 Y -2 0 0 -2 -4 3 0 -3 6 -3 -3 -1 -2 0 0 -2 -2 -1 5 -3 0 4 3 0 0 19 6 0 26 0 0 0 0 0 4 0 0 0 38 0 0.66 0.26 25 M -2 -2 -3 -4 -2 -1 -3 -4 -3 1 3 -2 8 -1 -3 -2 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 18 0 82 0 0 0 0 0 0 0 0.84 0.26 26 L -2 -2 -3 -4 -2 -2 -3 -4 -3 1 3 -2 6 0 -3 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 3 42 0 51 0 0 0 0 0 0 0 0.66 0.25 27 E -1 2 0 2 -3 0 4 -2 -1 -4 -4 0 -3 -4 -2 3 0 -4 -3 -3 0 13 0 9 0 0 39 0 0 0 0 0 0 0 0 39 0 0 0 0 0.55 0.26 28 C -1 -4 -4 -4 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.89 0.26 29 V -1 -2 -2 -3 -2 -2 -2 -3 -3 1 0 -2 -1 -2 -2 0 5 -3 -2 3 0 0 0 0 0 0 0 0 0 4 3 0 0 0 0 0 55 0 0 38 0.52 0.26 30 C -1 -4 -4 -4 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.89 0.26 31 L -2 -3 -4 -5 -2 -3 -4 -5 -4 1 5 -3 1 0 -4 -3 -2 -3 -2 2 0 0 0 0 0 0 0 0 0 0 87 0 0 0 0 0 0 0 0 13 0.72 0.26 32 G -1 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.42 0.26 33 N -2 -1 7 1 -4 -1 0 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 94 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 1.12 0.26 34 G -1 -3 0 -2 -3 -3 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 3 -3 -4 0 0 4 0 0 0 0 90 0 0 0 0 0 0 0 0 0 6 0 0 1.24 0.26 35 K -2 3 -1 -2 -4 1 0 -2 -1 -4 -3 6 -2 -4 -2 -1 -1 -4 -3 -3 0 13 0 0 0 0 0 0 0 0 0 87 0 0 0 0 0 0 0 0 0.87 0.26 36 G -1 -3 -1 -2 -3 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.42 0.26 37 E -2 -1 -1 1 -5 1 6 -3 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 1.11 0.26 38 W -3 -4 -4 -5 -3 -3 -4 -4 -3 -2 -1 -4 -1 5 -5 -3 -3 10 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 42 0 0 0 58 0 0 1.82 0.26 39 T -1 0 2 -1 -3 0 -1 -2 -2 -1 -2 4 -2 -3 -2 0 4 -4 -3 -2 0 0 13 0 0 0 0 0 0 4 0 40 0 0 0 0 42 0 0 0 0.47 0.25 40 C -1 -4 -4 -4 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.87 0.25 41 K -2 1 1 2 -4 1 3 -2 -1 -4 -4 4 -3 -4 -2 -1 -1 -4 -3 -3 0 0 5 14 0 0 32 0 0 0 0 49 0 0 0 0 0 0 0 0 0.61 0.21 42 P -1 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -4 8 -1 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.29 0.21 43 I -1 -3 -4 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 23 11 0 0 0 0 0 0 0 0 66 0.49 0.14 K Lambda Standard Ungapped 0.1438 0.3204 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1727 0.3181 PSI Gapped 0.0529 0.2670