Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 G 0 -3 -1 -2 -3 -2 -3 7 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.18 2 V -1 1 -2 -3 -2 2 -1 -3 -2 2 -1 2 0 -2 -3 -2 -1 -4 -2 3 0 9 0 0 0 12 0 0 0 13 0 21 0 0 0 0 0 0 0 45 0.29 0.20 3 R -2 6 -2 -2 -4 0 -1 -3 -1 -4 -3 1 -2 -4 5 -1 -2 -4 -3 -3 0 68 0 0 0 0 0 0 0 0 0 0 0 0 32 0 0 0 0 0 1.02 0.20 4 V -1 -3 -3 -3 -2 -2 1 -4 -3 2 0 -2 3 -2 -3 -2 -1 -4 -2 5 0 0 0 0 0 0 12 0 0 0 0 0 11 0 0 0 0 0 0 78 0.50 0.23 5 K -2 6 -1 -2 -4 0 2 -3 -1 -1 -3 3 -2 -4 -3 -1 -2 -4 -3 -3 0 62 0 0 0 0 17 0 0 7 0 14 0 0 0 0 0 0 0 0 0.73 0.26 6 I -2 -3 0 -3 -2 -3 -3 0 -3 4 1 -3 0 -1 -3 -2 -1 -4 -2 4 0 0 8 0 0 0 0 9 0 39 7 0 0 0 0 0 0 0 0 37 0.41 0.26 7 S -1 -2 1 2 -3 0 4 -2 -2 -3 -3 -1 -2 -4 -2 1 3 -4 -3 -2 0 0 7 13 0 0 36 0 0 0 0 0 0 0 0 12 32 0 0 0 0.53 0.28 8 F -1 -4 -4 -4 -3 -4 -4 -4 -2 4 1 -4 0 5 -4 -3 -2 -1 3 1 5 0 0 0 0 0 0 0 0 35 11 0 0 32 0 0 0 0 12 5 0.55 0.29 9 E 0 2 -1 0 -4 1 5 -3 -1 -1 -3 0 -2 -4 -2 -1 1 -4 -3 -2 7 11 0 0 0 0 66 0 0 6 0 0 0 0 0 0 11 0 0 0 0.64 0.29 10 G -1 -3 -1 -2 -4 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -3 -4 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.45 0.28 11 I -2 -2 -3 -3 -2 -2 -1 -4 -3 4 0 1 1 -2 -3 -2 2 -4 -2 3 0 0 0 0 0 0 5 0 0 41 0 14 5 0 0 0 14 0 0 20 0.34 0.28 12 A 6 -2 -2 -3 -1 -2 -2 -1 -3 -2 -2 -2 -2 -3 -2 0 -1 -4 -3 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.81 0.29 13 E -2 -1 -2 0 -3 0 5 -3 -2 1 1 1 -1 -2 -3 -1 0 -4 -3 -1 0 0 0 0 0 0 54 0 0 14 19 6 0 0 0 0 6 0 0 0 0.44 0.29 14 D -3 -3 1 7 -5 -1 1 -2 -2 -4 -5 -2 -4 -5 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.40 0.29 15 I -2 -4 -4 -4 -2 -4 -4 -5 -4 5 1 -4 0 -1 -4 -3 -1 -4 -2 4 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0 0 0 0 0 37 0.74 0.29 16 D -3 -3 1 7 -5 -1 1 -2 -2 -4 -5 -2 -4 -5 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.40 0.29 17 D -2 -1 0 4 -4 2 5 -3 -1 -4 -4 0 -3 -4 -2 0 -2 -4 -3 -4 0 0 0 25 0 7 62 0 0 0 0 0 0 0 0 6 0 0 0 0 0.86 0.29 18 F -2 -2 1 3 -3 -1 1 -3 -1 -2 0 0 -2 4 -3 -1 0 -2 2 -2 0 0 6 23 0 0 9 0 0 0 9 6 0 28 0 4 5 0 9 0 0.34 0.29 19 G -1 -3 -1 -2 -4 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -3 -4 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.45 0.29 20 R 4 3 0 -2 -2 -1 -2 -1 -2 -2 -1 -1 -2 -3 -2 0 -1 -4 -3 -1 67 23 6 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0.50 0.29 21 L -2 -3 -5 -5 -2 -3 -4 -5 -4 1 5 -3 1 0 -4 -3 -2 -3 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.86 0.29 22 I -2 -4 -4 -4 -2 -4 -4 -5 -4 5 3 -4 1 -1 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0 0 0 0.70 0.29 23 I -1 -3 -4 -4 -2 -3 -4 -4 -4 2 2 -3 0 -1 -3 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 5 20 0 0 0 0 0 0 0 0 75 0.66 0.29 24 R -2 6 -1 -2 -4 0 1 -3 -1 -4 -3 3 -2 -4 -3 -1 -2 -4 -3 -3 0 72 0 0 0 0 9 0 0 0 0 18 0 0 0 0 0 0 0 0 0.95 0.29 25 L -2 1 -2 0 -3 1 -1 -3 -2 0 2 2 0 -2 -3 0 2 -3 -2 -1 0 9 0 5 0 6 0 0 0 6 34 15 0 0 0 4 21 0 0 0 0.22 0.29 26 D -2 -1 1 3 -4 0 4 0 -1 -4 -4 1 -3 -4 2 1 -1 -4 -3 -4 0 0 6 21 0 0 41 7 0 0 0 6 0 0 8 10 0 0 0 0 0.57 0.29 27 S -2 -2 4 5 -3 -1 0 0 -2 -4 -4 -1 -3 -4 -2 2 0 -5 -3 -3 0 0 23 47 0 0 0 6 0 0 0 0 0 0 0 19 6 0 0 0 0.70 0.29 28 G -1 -3 -1 -2 -4 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -3 -4 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.45 0.29 29 E -1 2 1 -1 -3 0 3 -2 1 -2 -3 1 -2 -3 -2 2 1 -4 -2 0 0 13 6 0 0 0 26 0 4 0 0 9 0 0 0 18 12 0 0 11 0.31 0.29 30 V -2 -2 -3 -3 -2 -2 -2 -4 -3 2 2 2 0 -1 -3 -2 0 -3 -2 3 0 0 0 0 0 0 0 0 0 15 29 19 0 0 0 0 6 0 0 31 0.35 0.29 31 K -2 2 -1 0 -4 2 4 -3 -1 -3 -3 4 -2 -4 -2 -1 -2 -4 -3 -1 0 13 0 0 0 5 43 0 0 0 0 31 0 0 0 0 0 0 0 8 0.59 0.29 32 K -1 6 -1 -2 -4 0 -1 -3 -1 -4 -3 4 -2 -4 -3 -1 -2 -4 -3 -3 5 64 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0.89 0.29 33 V -1 -4 -4 -4 -2 -3 -4 -4 -4 4 0 -3 0 -1 -4 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 66 0.72 0.29 34 I -2 -3 -4 -4 -2 -3 -4 -5 -3 3 4 -3 1 1 -4 -3 -2 -2 1 3 0 0 0 0 0 0 0 0 0 14 48 0 0 6 0 0 0 0 6 25 0.52 0.29 35 Y 3 -2 -2 -3 -2 -2 -2 -2 2 -3 -3 -2 -2 0 -2 2 -1 -1 6 -2 30 0 0 0 0 0 0 0 6 0 0 0 0 0 0 26 0 0 38 0 0.54 0.29 36 G -1 -3 -1 0 -4 -3 -3 7 -3 -5 -5 -2 -4 -4 -3 -1 -2 -4 -4 -4 0 0 0 7 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.29 37 D -3 -3 1 7 -5 -1 1 -2 -2 -4 -5 -2 -4 -5 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.40 0.29 38 V -1 -4 -4 -4 -2 -3 -3 -4 -4 2 1 -3 0 -2 -3 -3 -1 -4 -2 6 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 94 0.75 0.28 39 S 0 -2 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -2 5 2 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 9 0 0 0 0.76 0.27 40 L -2 -3 -4 -4 -2 -3 -4 -5 -4 3 4 -3 1 0 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 24 69 0 0 0 0 0 0 0 0 7 0.64 0.24 41 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -4 -3 -2 -2 -4 -3 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.17 0.24 42 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.05 0.14 43 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.58 0.08 K Lambda Standard Ungapped 0.1520 0.3265 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1780 0.3154 PSI Gapped 0.0545 0.2670