Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -2 -3 -2 -1 -2 -3 -2 1 2 -2 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.45 0.05 2 N -2 -1 5 4 -3 0 0 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -3 -3 0 0 69 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.05 3 I -1 -3 -4 -4 -1 -3 -3 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 26 0.51 0.10 4 D -2 -2 0 5 -3 -1 0 -2 -2 2 -1 -2 -1 -2 -2 -1 -1 -4 -3 0 0 0 0 68 0 0 0 0 0 32 0 0 0 0 0 0 0 0 0 0 0.57 0.10 5 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.89 0.10 6 I -2 -3 -4 -4 -2 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 76 24 0 0 0 0 0 0 0 0 0 0.53 0.12 7 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 0 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.12 8 R -1 5 -1 -2 -4 1 0 -2 -1 -3 -3 4 -2 -3 -2 -1 -1 -3 -2 -3 0 51 0 0 0 0 0 0 0 0 0 49 0 0 0 0 0 0 0 0 0.72 0.12 9 K -1 1 -1 0 -4 1 3 -2 -1 -3 -3 5 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 24 0 0 0 0 76 0 0 0 0 0 0 0 0 0.63 0.12 10 I -2 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.61 0.12 11 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -1 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.15 0.12 12 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 0 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.12 13 A 4 -2 -2 -3 6 -2 -2 -1 -2 -2 -2 -2 -1 -3 -2 0 -1 -3 -2 -1 76 0 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.57 0.12 14 I -2 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.61 0.12 15 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 0 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.12 16 K -1 4 0 -1 -3 1 0 -2 -1 -3 -3 4 -2 -3 -2 2 -1 -3 -2 -3 0 35 0 0 0 0 0 0 0 0 0 41 0 0 0 24 0 0 0 0 0.52 0.12 17 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 0 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.12 18 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -1 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.15 0.12 19 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -1 -1 -3 -1 4 -4 -2 -2 2 7 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 24 0 0 0 0 76 0 0.99 0.12 20 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 0 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.12 21 T -1 0 0 -1 -2 0 -1 -2 4 -2 -2 2 -1 -3 -2 0 4 -3 -1 -1 0 0 0 0 0 0 0 0 19 0 0 24 0 0 0 0 57 0 0 0 0.42 0.12 22 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.64 0.12 23 L -2 4 5 0 -3 0 -1 -2 0 -2 0 0 -1 -2 -3 -1 -1 -3 -2 -2 0 35 49 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0.46 0.12 24 S 0 0 -1 -1 -2 0 -1 -2 -2 -1 -2 2 -1 -3 -2 3 3 -3 -2 1 0 0 0 0 0 0 0 0 0 0 0 24 0 0 0 33 24 0 0 19 0.27 0.12 25 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.64 0.12 26 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.64 0.12 27 N -2 0 3 4 -4 0 3 -2 -1 -4 -4 2 -3 -4 -2 0 -1 -4 -3 -3 0 0 17 41 0 0 24 0 0 0 0 19 0 0 0 0 0 0 0 0 0.61 0.12 28 K -1 1 -1 0 -4 1 4 -2 -1 -3 -3 4 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 43 0 0 0 0 57 0 0 0 0 0 0 0 0 0.62 0.12 29 R -2 6 -1 -2 -4 1 0 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.12 30 K -1 1 -1 1 -4 1 5 -2 -1 -4 -3 3 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 67 0 0 0 0 33 0 0 0 0 0 0 0 0 0.69 0.12 31 E -1 1 -1 0 -4 1 4 -2 -1 -3 -3 4 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 57 0 0 0 0 43 0 0 0 0 0 0 0 0 0.65 0.12 32 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 1 4 -4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 76 0 0 24 0 0 0 0 0 0 0.55 0.12 33 M -2 -2 -3 -4 -2 -2 -3 -4 -3 1 4 -3 5 0 -3 -3 -1 -2 -1 0 0 0 0 0 0 0 0 0 0 0 67 0 33 0 0 0 0 0 0 0 0.54 0.12 34 E -1 0 -1 0 -4 1 3 -2 -1 -3 -3 4 -2 -4 4 -1 -1 -4 -3 -3 0 0 0 0 0 0 33 0 0 0 0 43 0 0 24 0 0 0 0 0 0.67 0.12 35 G -1 0 0 3 -3 0 3 2 -1 -3 -3 2 -2 -4 -2 1 -1 -4 -3 -3 0 0 0 19 0 0 24 17 0 0 0 24 0 0 0 16 0 0 0 0 0.40 0.12 36 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.64 0.12 37 P -1 -2 -1 -2 -2 -1 -1 -2 -2 -3 -3 -1 -2 -3 6 2 2 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57 19 24 0 0 0 1.10 0.12 38 K 1 1 -1 0 -3 1 3 -2 -1 -3 -3 4 -2 -3 -1 0 -1 -3 -2 -2 19 0 0 0 0 0 24 0 0 0 0 57 0 0 0 0 0 0 0 0 0.47 0.12 39 D -2 -1 3 4 -4 1 4 -2 -1 -4 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 24 33 0 0 43 0 0 0 0 0 0 0 0 0 0 0 0 0 0.69 0.12 40 K -1 1 -1 -1 -3 1 3 -3 -1 1 -1 4 -1 -3 -2 -1 -1 -3 -2 -1 0 0 0 0 0 0 24 0 0 24 0 51 0 0 0 0 0 0 0 0 0.34 0.12 41 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.64 0.12 42 S 0 3 0 -1 -2 0 0 -1 -1 -3 -3 3 -2 -3 -2 3 0 -3 -2 -2 0 24 0 0 0 0 0 0 0 0 0 24 0 0 0 51 0 0 0 0 0.44 0.12 43 E -1 -1 -1 1 -3 1 5 -3 -1 -2 -1 0 3 -3 -2 -1 -1 -3 -2 -2 0 0 0 0 0 0 76 0 0 0 0 0 24 0 0 0 0 0 0 0 0.60 0.12 44 I -2 -3 -4 -4 -2 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 76 24 0 0 0 0 0 0 0 0 0 0.53 0.12 45 L -2 -2 -2 -3 -2 -2 -2 -4 5 0 3 -2 1 1 -3 -2 -2 -1 4 -1 0 0 0 0 0 0 0 0 24 0 51 0 0 0 0 0 0 0 24 0 0.44 0.12 46 E -1 0 -1 1 -4 4 5 -2 0 -4 -3 1 -2 -4 -2 0 -1 -3 -2 -3 0 0 0 0 0 24 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0.80 0.12 47 K -1 4 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -3 -2 -1 -1 -3 -2 -3 0 41 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0.69 0.12 48 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -1 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.15 0.12 49 R -1 5 -1 -1 -4 3 0 -2 -1 -3 -3 3 -2 -3 -2 -1 -1 -3 -2 -3 0 51 0 0 0 24 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0.67 0.12 50 K -1 0 0 -1 -3 1 2 -2 5 -3 -3 3 -2 -3 -2 0 2 -3 -1 -2 0 0 0 0 0 0 19 0 24 0 0 33 0 0 0 0 24 0 0 0 0.41 0.12 51 R -2 6 -1 -2 -4 1 0 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.12 52 L -2 -2 -3 -4 -2 -2 -3 -4 -3 1 4 -2 6 0 -3 -2 -1 -2 -1 0 0 0 0 0 0 0 0 0 0 0 51 0 49 0 0 0 0 0 0 0 0.54 0.12 53 E -1 3 -1 0 -4 1 4 -2 -1 -4 -3 3 -2 -4 -2 -1 -1 -3 -2 -3 0 19 0 0 0 0 57 0 0 0 0 24 0 0 0 0 0 0 0 0 0.63 0.12 54 I -1 -1 -3 -3 -2 -1 -2 -3 -3 4 0 2 0 -1 -3 -2 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 51 0 24 0 0 0 0 0 0 0 24 0.31 0.12 55 I -2 -3 -4 -4 -2 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 76 24 0 0 0 0 0 0 0 0 0 0.53 0.12 56 E -1 0 -1 1 -4 1 5 -2 -1 -4 -3 3 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 0 76 0 0 0 0 24 0 0 0 0 0 0 0 0 0.74 0.12 57 K -1 1 -1 0 -4 1 4 -2 -1 -3 -3 4 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 43 0 0 0 0 57 0 0 0 0 0 0 0 0 0.62 0.12 58 R -2 5 -1 -2 -3 0 -1 -3 -1 1 -1 3 -1 -2 -2 -1 -1 -3 -2 -1 0 51 0 0 0 0 0 0 0 24 0 24 0 0 0 0 0 0 0 0 0.46 0.12 59 K -1 1 -1 -2 -3 0 0 -2 -2 2 -1 4 -1 -2 -2 -1 -1 -3 -2 0 0 0 0 0 0 0 0 0 0 32 0 68 0 0 0 0 0 0 0 0 0.34 0.10 60 T 2 -1 -1 -1 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 -1 3 3 -3 -2 -1 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26 42 0 0 0 0.40 0.10 61 A 2 -2 -1 -1 -1 -1 -1 -1 -2 -1 -2 -1 -1 -2 -1 4 1 -3 -2 1 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 0 21 0.32 0.10 62 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.60 0.10 63 F -2 -1 -2 -3 -3 -1 -2 -3 -1 -1 -1 2 -1 6 -3 -2 -2 0 2 -2 0 0 0 0 0 0 0 0 0 0 0 32 0 68 0 0 0 0 0 0 0.53 0.10 64 Q -1 3 0 -1 -3 5 1 -2 0 -3 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 0 26 0 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.71 0.10 65 E -1 0 0 1 -4 4 5 -2 0 -4 -3 1 -2 -4 -2 0 -1 -3 -2 -3 0 0 0 0 0 32 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.10 66 I 2 -3 -3 -3 -1 -2 -3 -2 -3 3 2 -2 1 -1 -2 -1 -1 -3 -2 1 32 0 0 0 0 0 0 0 0 42 26 0 0 0 0 0 0 0 0 0 0.27 0.10 67 N -1 0 4 0 -3 0 0 -1 0 -3 -3 3 -2 -3 -2 2 0 -4 -2 -3 0 0 42 0 0 0 0 0 0 0 0 32 0 0 0 26 0 0 0 0 0.46 0.10 68 V -1 -2 3 -1 -2 -2 -2 3 -2 0 -1 -2 -1 -2 -3 -1 -1 -3 -2 2 0 0 32 0 0 0 0 26 0 0 0 0 0 0 0 0 0 0 0 42 0.29 0.10 69 I -2 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 1 0 -3 -3 -1 -2 -2 1 0 0 0 0 0 0 0 0 0 42 58 0 0 0 0 0 0 0 0 0 0.49 0.10 70 R -2 6 -1 -2 -4 1 0 -3 -1 -3 -3 2 -2 -3 -3 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.10 71 E -2 -1 3 0 -3 0 3 -2 -1 -1 2 -1 0 -2 -2 -1 -1 -3 -2 -1 0 0 26 0 0 0 42 0 0 0 32 0 0 0 0 0 0 0 0 0 0.31 0.10 72 A 3 -2 -2 -2 -2 -2 -2 3 -3 2 -1 -2 -1 -2 -2 0 -1 -3 -2 0 42 0 0 0 0 0 0 32 0 26 0 0 0 0 0 0 0 0 0 0 0.33 0.10 73 R -1 4 -1 0 -4 1 3 -2 -1 -3 -3 3 -2 -3 -2 -1 -1 -3 -2 -3 0 42 0 0 0 0 32 0 0 0 0 26 0 0 0 0 0 0 0 0 0.59 0.10 74 S 0 0 0 -1 -2 0 0 3 -1 -3 -3 3 -2 -3 -2 3 0 -3 -2 -3 0 0 0 0 0 0 0 26 0 0 0 32 0 0 0 42 0 0 0 0 0.40 0.10 75 S 3 -1 0 -1 -1 -1 -1 0 -1 -2 -2 -1 -2 -3 -1 4 1 -3 -2 -1 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 68 0 0 0 0 0.47 0.10 76 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.60 0.10 77 Q -1 1 0 -1 -3 5 1 -2 0 -3 -3 3 -1 -4 -2 0 -1 -3 -2 -3 0 0 0 0 0 68 0 0 0 0 0 32 0 0 0 0 0 0 0 0 0.66 0.10 78 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.59 0.05 K Lambda Standard Ungapped 0.1329 0.3115 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1555 0.3178 PSI Gapped 0.0476 0.2670