Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 S 1 -1 1 0 -1 0 0 0 -1 -2 -2 0 -1 -2 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 2 S 1 -1 1 0 -1 0 0 0 -1 -2 -2 0 -1 -2 -1 4 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 3 G 0 -2 0 -1 -2 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -2 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 4 M -1 -2 -3 -4 -2 -1 -3 -3 -2 1 2 -2 7 0 -3 -2 -1 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.61 0.11 5 S 1 -1 0 -1 -1 0 0 -1 -1 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.61 0.11 6 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 5 -3 2 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 11 89 0 0 0 0 0 0 0 0 0 0.59 0.12 7 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 4 -3 1 4 -4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 74 0 0 26 0 0 0 0 0 0 0.55 0.12 8 T 0 -2 -1 -2 -2 -1 -2 3 -2 -2 -2 -1 -2 -3 -2 1 5 -3 -2 -1 0 0 0 0 0 0 0 26 0 0 0 0 0 0 0 0 74 0 0 0 0.53 0.12 9 E -2 -1 0 4 -4 1 5 -2 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 26 0 0 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.12 10 V -1 -3 -2 -3 -1 -2 -2 -3 -3 2 0 -2 0 -2 -2 -1 3 -3 -2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26 0 0 74 0.40 0.12 11 E -1 -1 -1 1 -3 1 5 -3 -1 2 -1 0 -1 -3 -2 -1 -1 -3 -2 -1 0 0 0 0 0 0 74 0 0 26 0 0 0 0 0 0 0 0 0 0 0.52 0.12 12 T 2 -2 -1 -2 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -2 1 5 -3 -2 -1 23 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77 0 0 0 0.54 0.14 13 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -2 -1 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.18 0.14 14 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 2 -3 1 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 77 0.49 0.14 15 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 1 1 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 83 0 0 6 0 0 0 0 0 0 0.47 0.14 16 S 1 -1 0 -1 -1 -1 -1 -1 -1 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.65 0.14 17 I -2 -3 -4 -4 -2 -3 -4 -4 -4 5 2 -3 1 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 78 22 0 0 0 0 0 0 0 0 0 0.57 0.15 18 I -1 -3 -3 -3 -2 -3 -3 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 29 0.43 0.15 19 P -1 -2 -2 -1 -3 -1 2 -3 -2 -3 -3 -1 -3 -4 7 -1 -2 -4 -3 -3 0 0 0 0 0 0 21 0 0 0 0 0 0 0 71 0 0 0 0 0 1.42 0.16 20 S 0 -2 0 3 -2 -1 0 -1 -2 -1 -2 -1 -2 -3 -2 4 0 -3 -2 -2 0 0 0 21 0 0 0 0 0 8 0 0 0 0 0 63 0 0 0 0 0.37 0.16 21 G 1 0 -1 -2 -3 -2 -2 5 -2 -4 -4 -1 -3 -3 -2 -1 -2 -3 -3 -3 14 8 0 0 0 0 0 71 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.16 22 P -1 -2 -2 -1 -4 -1 2 -3 -2 -4 -4 -1 -3 -4 8 -1 -2 -4 -3 -3 0 0 0 0 0 0 21 0 0 0 0 0 0 0 79 0 0 0 0 0 1.66 0.15 23 L -1 -3 -2 -3 -2 -2 -3 2 -3 0 3 -2 1 -1 1 0 -1 -3 -2 -1 0 0 0 0 0 0 0 21 0 0 59 0 0 0 7 14 0 0 0 0 0.29 0.15 24 K -1 2 -1 -1 -4 2 1 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 7 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0.72 0.15 25 A 5 -2 -2 -2 -1 -1 -1 -1 -2 -2 -2 -1 -2 -3 3 1 -1 -3 -2 -1 86 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0.60 0.15 26 E -2 2 -1 2 -4 1 5 -3 -1 -4 -3 1 -3 -4 -2 -1 -1 -4 -3 -3 0 14 0 11 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.15 27 I -1 -3 -3 -3 -2 -3 -3 -4 -3 5 2 -3 1 -1 -3 0 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 65 21 0 0 0 0 14 0 0 0 0 0.40 0.15 28 A 5 -2 -2 -2 -1 -1 -1 0 3 -2 -2 -1 -2 -3 -1 1 -1 -3 -1 -1 86 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0.52 0.15 29 Q -1 2 -1 0 -4 6 3 -3 0 -4 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 0 14 0 0 0 65 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.15 30 K -2 5 0 2 -4 1 0 -2 -1 -4 -3 4 -2 -4 -2 -1 -1 -4 -2 -3 0 50 0 14 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0.65 0.15 31 L -2 -2 -3 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 81 0 5 0 0 0 0 0 0 0 0.44 0.15 32 E -1 -1 0 1 -4 1 5 -3 5 -4 -3 0 -2 -3 -2 -1 -1 -3 -1 -3 0 0 0 0 0 0 77 0 23 0 0 0 0 0 0 0 0 0 0 0 0.77 0.12 33 D -1 -2 0 6 5 -1 0 0 -2 -3 -4 -2 -3 -4 -2 1 -1 -4 -4 -3 0 0 0 64 18 0 0 6 0 0 0 0 0 0 0 11 0 0 0 0 0.76 0.19 34 V -1 -3 -4 -4 -2 -3 -3 -4 -4 2 0 -3 0 -1 -3 -3 -1 7 -1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 0 82 0.70 0.19 35 F -3 -4 -4 -4 -3 -4 -4 -4 -2 -1 1 -4 0 7 -4 -3 -3 0 2 -1 0 0 0 0 0 0 0 0 0 0 8 0 0 92 0 0 0 0 0 0 1.04 0.19 36 A 4 -2 -2 -2 -1 -2 -2 2 -2 -2 -2 -2 -2 -3 -2 1 -1 -3 -3 0 65 0 0 0 0 0 0 18 0 0 0 0 0 0 0 10 0 0 0 7 0.47 0.19 37 G -1 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -3 -3 -1 -2 4 -3 -4 0 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 0 7 0 0 1.05 0.19 38 K -1 2 -1 -1 -3 0 0 -2 -1 -3 -3 5 -2 -3 -2 -1 -1 -3 -2 -3 0 10 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0.44 0.19 39 N -2 -1 6 1 -3 0 2 -1 0 -3 -3 -1 -3 -3 -2 0 -1 -4 -3 -3 0 0 60 5 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0.53 0.17 40 T -1 -2 -1 -2 -2 -2 -2 -2 -2 -1 -1 -2 -1 3 -2 1 5 -2 -1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 9 65 0 0 0 0.42 0.17 41 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.06 0.17 42 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.70 0.17 43 E -2 -1 0 4 -4 1 5 0 -1 -3 -3 0 -3 -4 -2 -1 -1 -4 -3 -2 0 0 0 27 0 0 61 7 0 0 0 0 0 0 0 0 0 0 0 5 0.68 0.17 44 A 4 -2 -1 -2 -1 -1 -1 -1 -2 -1 -2 -1 -1 -3 -1 2 1 -3 -2 1 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 8 0 0 11 0.37 0.13 45 L 1 -3 -3 -4 -2 -2 -3 -3 -3 1 4 -3 1 0 -3 -2 -1 -2 -2 0 22 0 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 0 0 0 0.43 0.13 46 M -2 -2 -3 -4 -2 -1 -3 -4 -3 2 3 -2 6 0 -3 -2 -1 -2 -2 1 0 0 0 0 0 0 0 0 0 7 30 0 63 0 0 0 0 0 0 0 0.53 0.13 47 E -1 0 -1 1 -4 2 6 -3 -1 -4 -3 0 -3 -4 -2 -1 -1 -3 -3 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.13 48 W -3 -3 -4 -5 -3 -2 -3 -3 -3 -3 -2 -4 -2 1 -4 -3 -3 12 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.63 0.13 49 L -2 -3 -4 -4 -2 -3 -4 -4 -4 3 4 -3 2 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 22 78 0 0 0 0 0 0 0 0 0 0.56 0.13 50 K -1 1 -1 -1 -2 0 0 -2 -1 -2 -2 4 -2 -2 -1 -1 -1 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0.03 0.11 51 T 1 -2 3 -1 -2 -1 -1 -2 -2 -2 -2 -1 -1 -3 -2 1 5 -3 -2 -1 18 0 18 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 0.49 0.17 52 R -2 6 -1 -2 -4 1 0 -3 -1 -4 -3 4 -2 -4 -2 -1 -2 -3 -2 -3 0 69 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0.84 0.17 53 P -2 3 -2 -2 -4 -1 -1 -3 -2 -3 -3 0 -3 -4 7 -1 0 -4 -3 -3 0 31 0 0 0 0 0 0 0 0 0 0 0 0 64 0 5 0 0 0 1.32 0.17 54 I -2 -3 -3 -4 6 -3 -4 -4 -3 4 0 -3 0 -1 -3 -2 -1 -3 -2 1 0 0 0 0 28 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 0.49 0.17 55 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.70 0.17 56 S 0 -1 0 -1 -1 -1 -1 -1 -2 -2 -2 -1 -2 -3 -1 4 3 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60 28 0 0 0 0.41 0.17 57 P -1 -3 -1 3 -4 -1 -1 -2 -2 -4 -4 -1 -3 -4 7 0 -1 -5 -4 -3 0 0 0 28 0 0 0 0 0 0 0 0 0 0 66 6 0 0 0 0 1.41 0.17 58 L -2 -3 -4 -4 -2 -3 -4 -4 -4 3 4 -3 1 0 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 28 72 0 0 0 0 0 0 0 0 0 0.59 0.17 59 T -1 -1 -1 -1 -2 3 0 -2 -1 -2 -2 -1 -1 -3 -2 0 4 -2 -2 -1 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 46 0 0 0 0.23 0.17 60 K -1 2 -1 -1 -3 1 0 -2 -1 -3 -3 5 -2 -3 -2 -1 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0 0 0 0 0.56 0.17 61 G 2 -2 -1 -2 -2 -2 -2 5 -2 -3 -3 -2 -2 -3 -2 0 -2 -3 -3 -2 28 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0.60 0.17 62 I -2 -3 -4 -4 -2 -3 -3 -4 -3 4 3 -3 1 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 50 32 0 0 0 0 0 0 0 0 6 0.38 0.16 63 L -2 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 1 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 32 53 0 0 0 0 0 0 0 0 4 0.39 0.16 64 G 0 -3 -1 -2 -3 -2 -3 6 -3 -5 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.29 0.16 65 F 2 -3 -3 -4 -2 -3 -3 -2 -2 -1 -1 -3 -1 6 -3 -1 -2 0 2 -1 32 0 0 0 0 0 0 0 0 0 0 0 0 68 0 0 0 0 0 0 0.63 0.16 66 V 0 -2 -2 -3 -1 -2 -2 -3 -3 1 0 -2 0 -2 -2 2 0 -4 -2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 0 0 0 68 0.36 0.16 67 F -3 -4 -4 -4 -3 -4 -4 -4 -2 3 0 -4 0 6 -4 -3 -2 0 2 0 0 0 0 0 0 0 0 0 0 32 0 0 0 68 0 0 0 0 0 0 0.73 0.16 68 T -1 -2 -1 -2 7 -2 -2 -2 -3 -1 -2 -2 -1 -3 -2 0 5 -3 -2 -1 0 0 0 0 32 0 0 0 0 0 0 0 0 0 0 0 68 0 0 0 0.72 0.16 69 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 4 -3 1 4 -4 -3 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 69 0 0 31 0 0 0 0 0 0 0.56 0.13 70 T -1 -2 -1 -2 -1 -2 -2 -3 -3 0 2 -2 0 -2 -2 0 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 69 0 0 0 0.43 0.13 71 V -1 -1 -2 -3 -2 -1 -1 -3 -3 1 0 2 0 -2 -2 -2 -1 -4 -2 4 0 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 69 0.32 0.13 72 P -1 -3 -2 -2 -3 -2 -2 -3 -3 -3 -3 -1 -3 -4 8 -1 -2 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0 1.89 0.13 73 S 0 0 0 -1 3 0 0 -1 -1 -3 -3 3 -2 -3 -1 4 0 -3 -2 -2 0 0 0 0 8 0 0 0 0 0 0 31 0 0 0 61 0 0 0 0 0.43 0.13 74 R -2 6 -1 -1 -4 1 1 -3 -1 -4 -3 3 -2 -4 -2 -1 -2 -3 -2 -3 0 70 0 0 0 0 11 0 0 0 0 19 0 0 0 0 0 0 0 0 0.77 0.15 75 R -2 7 -1 -2 -4 1 -1 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.02 0.15 76 R -2 6 -1 -2 -4 1 0 -3 -1 -4 -3 3 -2 -4 -3 -1 -2 -3 -2 -3 0 88 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0.93 0.15 77 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.06 0.15 78 V -1 -3 -3 -4 -2 -3 -3 0 -4 4 0 -3 0 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 10 0 31 0 0 0 0 0 0 0 0 0 59 0.43 0.15 79 Q -1 2 0 -1 -3 6 1 -2 0 -3 -3 1 -1 -4 -2 0 2 -3 -2 -2 0 10 0 0 0 71 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0.64 0.15 80 N -1 -1 5 1 -3 0 2 -1 0 -3 -3 0 -2 -3 -2 1 1 -4 -2 -3 0 0 58 0 0 0 19 0 0 0 0 0 0 0 0 5 12 0 0 0 0.53 0.15 81 A 5 -2 -2 -2 -1 -1 -1 -1 -2 -2 -2 -1 -2 -3 4 0 -1 -3 -3 -1 81 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0.63 0.15 82 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.68 0.15 83 N -1 -1 6 2 -3 -1 0 -1 0 -3 -4 -1 -3 -3 -2 2 0 -4 -3 -3 0 0 58 12 0 0 0 0 0 0 0 0 0 0 0 22 0 0 0 0 0.58 0.17 84 D -2 -2 0 6 -4 -1 2 3 -2 -4 -4 -1 -4 -4 -2 -1 -2 -4 -4 -4 0 0 0 63 0 0 9 28 0 0 0 0 0 0 0 0 0 0 0 0 0.81 0.16 85 P 1 -2 -3 -3 -3 -2 -2 -2 -3 -1 -1 -2 4 -3 7 -1 -1 -3 -3 -1 12 0 0 0 0 0 0 0 0 0 0 0 28 0 59 0 0 0 0 0 1.12 0.16 86 N 0 -1 6 0 -3 -1 -1 3 -1 -4 -4 -1 -3 -4 -3 0 -1 -4 -3 -3 7 0 66 0 0 0 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.16 87 N -2 -1 6 0 -3 -1 -1 -1 0 -3 -3 -1 -2 -3 -2 0 3 -4 -3 -2 0 0 73 0 0 0 0 0 0 0 0 0 0 0 0 0 27 0 0 0 0.75 0.16 88 M -1 -2 -2 -3 -2 -1 -2 -3 -2 0 1 -2 7 -1 -3 -1 3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 73 0 0 0 27 0 0 0 0.53 0.16 89 D 2 -2 0 6 -3 -1 1 -1 2 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 27 0 0 66 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0.69 0.16 90 R -1 5 -1 -2 -3 0 -1 -3 -1 -3 -3 3 -2 -3 -2 0 3 -3 -2 -2 0 48 0 0 0 0 0 0 0 0 0 25 0 0 0 0 27 0 0 0 0.57 0.16 91 A 4 0 -2 -2 -2 -1 -1 -1 -2 -2 -2 3 -2 -3 1 0 -1 -3 -2 -1 66 0 0 0 0 0 0 0 0 0 0 27 0 0 7 0 0 0 0 0 0.45 0.16 92 V -1 -1 -3 -3 -2 -1 -2 -3 -3 1 0 2 0 -2 -3 -2 -1 -4 -2 4 0 0 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 0 73 0.37 0.16 93 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.79 0.16 94 L 2 -2 -3 -3 -2 1 -2 -3 -3 1 3 -2 1 -1 -3 -1 -1 -3 -2 0 27 0 0 0 0 11 0 0 0 7 55 0 0 0 0 0 0 0 0 0 0.30 0.16 95 Y -2 -2 0 -1 -3 -1 2 -3 1 -2 -2 -1 -2 2 -3 -2 -2 1 7 -2 0 0 7 0 0 0 27 0 0 0 0 0 0 0 0 0 0 0 66 0 0.73 0.16 96 K -2 5 -1 -2 -4 1 0 -3 -1 -4 -3 4 -2 -4 -2 -1 -1 -3 -2 -3 0 53 0 0 0 4 0 0 0 0 0 42 0 0 0 0 0 0 0 0 0.75 0.16 97 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.79 0.16 98 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 5 0 0 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 68 0 27 0 5 0 0 0 0 0 0.55 0.16 99 K -1 4 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 23 0 0 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 0 0.72 0.16 100 R -2 7 -1 -2 -4 1 0 -3 -1 -4 -3 2 -2 -4 -3 -1 -2 -3 -2 -3 0 93 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0.97 0.16 101 E -1 -1 -1 1 6 1 5 -3 -1 -3 -3 0 -2 -4 -2 -1 -1 -3 -3 -3 0 0 0 0 23 0 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0.78 0.16 102 I -1 -3 -3 -4 -2 -3 -3 -4 -4 5 1 -1 2 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 59 0 5 9 0 0 0 0 0 0 27 0.47 0.16 103 T 0 -1 0 -1 -2 -1 -1 -2 -2 -2 -2 0 -1 -3 1 2 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 5 0 0 6 23 66 0 0 0 0.53 0.16 104 F -3 -3 -3 -4 -3 -4 -4 -4 -2 -1 0 -4 0 7 -4 -3 -3 0 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 93 0 0 0 0 0 0 0.93 0.16 105 H -2 -1 0 -2 -3 0 -1 -3 9 -4 -3 -1 -2 -2 -3 -1 -2 -3 1 -3 0 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 0 1.04 0.16 106 G -1 -2 -1 -1 -3 -1 2 6 -2 -4 -4 -1 -3 -4 -2 -1 -2 -3 -3 -4 0 0 0 0 0 0 23 77 0 0 0 0 0 0 0 0 0 0 0 0 0.91 0.16 107 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.63 0.16 108 K -2 1 -1 -2 -3 0 0 -2 -1 -2 -2 5 -1 3 -2 -1 -2 -2 0 -2 0 0 0 0 0 0 0 0 0 0 0 66 0 23 0 0 0 0 0 0 0.39 0.16 109 E -1 -1 -1 1 -4 2 6 -3 -1 -4 -3 0 -3 -4 -2 -1 -1 -3 -3 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.94 0.13 110 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 44 0 0 0 0 0 0 0 0 0 56 0.52 0.13 111 A 4 -2 -1 -2 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 3 0 -3 -2 -1 74 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26 0 0 0 0 0.50 0.13 112 L -2 -2 -3 -2 -2 -1 2 -4 -2 1 4 -2 1 -1 -3 -2 -2 -2 -2 0 0 0 0 0 0 0 25 0 0 0 75 0 0 0 0 0 0 0 0 0 0.40 0.13 113 S 1 -2 0 -1 -2 -1 -1 3 -2 -3 -3 -1 -2 -3 -2 4 1 -3 -3 -3 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 75 0 0 0 0 0.56 0.13 114 Y -2 -2 -2 -3 -3 -1 -2 -3 5 -2 -2 -2 -2 2 -3 -2 -2 1 7 -2 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 75 0 0.96 0.13 115 S 0 -1 0 0 -2 0 2 -1 -1 -3 -3 -1 -2 -3 1 4 0 -3 -2 -2 0 0 0 0 0 0 23 0 0 0 0 0 0 0 7 55 0 0 0 0 0.35 0.19 116 T 2 -2 1 -1 -1 -1 -1 -1 -2 -2 -2 -1 -2 -3 -2 2 4 -3 -2 -1 17 0 6 0 0 0 0 0 0 0 0 0 0 0 0 23 39 0 0 0 0.28 0.19 117 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 2 -1 -3 -3 -3 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 23 0 0 0 0 0.96 0.19 118 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.19 119 L -2 -3 -4 -4 -2 -3 -4 -4 -4 1 5 -3 2 0 -4 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.70 0.17 120 A 4 -2 -2 -2 -1 -2 -2 -1 -2 -1 0 -2 -1 -2 3 0 -1 -3 -2 -1 55 0 0 0 0 0 0 0 0 0 15 0 0 0 15 0 0 0 0 0 0.29 0.17 121 S 0 -2 -1 -2 2 -1 -1 -2 -1 -2 -2 -1 -2 0 -2 3 1 -1 4 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 0 50 9 0 29 7 0.38 0.16 122 C -1 -4 -3 -4 10 -3 -4 -3 -4 -2 -2 -3 -2 -3 1 -1 -1 -3 -3 -1 0 0 0 0 91 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 1.47 0.16 123 M -2 -2 -3 -4 -2 -1 -3 -4 -2 1 3 -2 7 0 -3 -2 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 29 0 71 0 0 0 0 0 0 0 0.62 0.16 124 G -1 -3 -1 -2 -3 -2 -3 5 -3 -2 -1 -2 4 -2 -3 -1 -2 -3 -3 -2 0 0 0 0 0 0 0 71 0 0 0 0 29 0 0 0 0 0 0 0 0.77 0.16 125 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 1 0 -3 -3 -1 -2 -2 3 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 0 29 0.38 0.16 126 I -2 -3 -4 -4 -2 -2 -3 -4 -3 5 1 -3 5 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 71 0 0 29 0 0 0 0 0 0 0 0.55 0.16 127 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -2 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.21 0.16 128 N -2 -1 6 0 -3 -1 -1 -2 -1 -1 1 -1 -1 -2 -3 0 -1 -4 -2 -2 0 0 71 0 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 0.57 0.16 129 R -2 5 4 -1 -4 0 -1 -2 0 -4 -3 1 -2 -3 -3 -1 -1 -4 -2 -3 0 67 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.13 130 M -1 -2 -3 -3 -2 -1 -2 -3 -2 0 1 -2 6 -1 5 -2 -1 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 33 0 0 0 0 0 0.73 0.13 131 G -1 -2 -1 0 -4 0 3 5 -2 -4 -4 -1 -3 -4 -2 -1 -2 -3 -3 -4 0 0 0 0 0 0 35 65 0 0 0 0 0 0 0 0 0 0 0 0 0.80 0.15 132 T 1 -1 4 -1 -2 -1 -1 -1 -1 -2 -3 -1 -2 -3 -2 1 4 -4 -2 -1 19 0 35 0 0 0 0 0 0 0 0 0 0 0 0 6 40 0 0 0 0.44 0.15 133 V -1 -3 -3 -4 -2 -3 -3 -4 -1 1 0 -3 0 1 -3 -2 -1 -1 5 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35 65 0.50 0.15 134 T 0 -1 1 -1 -1 -1 -1 -2 -2 -2 -2 -1 -2 -3 -2 3 5 -3 -2 -1 0 0 5 0 0 0 0 0 0 0 0 0 0 0 0 35 60 0 0 0 0.54 0.15 135 T 0 -2 -1 -2 -2 -1 -2 -2 -2 0 0 -1 5 -2 -2 0 4 -3 -2 0 5 0 0 0 0 0 0 0 0 0 0 0 35 0 0 0 60 0 0 0 0.45 0.15 136 E -1 0 -1 1 -4 4 5 -3 0 -4 -3 1 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 31 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.17 137 V 1 -3 -2 -3 -1 -2 -2 0 -3 1 0 -2 0 -2 -2 0 -1 -3 -2 4 11 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 64 0.27 0.17 138 A 4 0 -2 -2 -2 0 -1 -1 -2 -2 -2 3 -2 -3 -1 0 -1 -3 -2 -1 69 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 0.47 0.17 139 F -3 -3 -4 -4 -3 -3 -4 -4 -2 0 3 -4 1 6 -4 -3 -2 0 2 -1 0 0 0 0 0 0 0 0 0 0 42 0 0 58 0 0 0 0 0 0 0.70 0.17 140 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -3 -4 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 0 0 1.06 0.17 141 L -1 -2 -2 -3 -2 -2 -3 -3 -3 1 4 -2 1 -1 1 -1 3 -3 -2 0 0 0 0 0 0 0 0 0 0 4 59 0 0 0 6 0 31 0 0 0 0.39 0.17 142 V -1 -3 -3 -4 -2 -3 -3 -4 -3 2 3 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 5 31 0 0 0 0 0 0 0 0 54 0.36 0.17 143 C -1 -4 -3 -4 10 -3 -4 -3 -3 -2 -2 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.40 0.17 144 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.62 0.15 145 T -1 -2 -1 -2 -1 -1 -2 -3 -2 0 2 -2 0 -2 -2 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 29 0 0 0 0 6 65 0 0 0 0.42 0.15 146 C -1 -4 -3 -4 10 -4 -4 -3 -4 -2 -2 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.62 0.15 147 E -1 -1 -1 1 -4 2 6 -3 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.96 0.15 148 Q -1 1 0 -1 -4 6 1 -2 2 -3 -3 3 -1 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 65 0 0 6 0 0 29 0 0 0 0 0 0 0 0 0.68 0.15 149 I -2 -2 -2 -3 -2 3 -1 -4 -2 5 1 -1 0 -1 -3 -2 -1 -3 -2 2 0 0 0 0 0 29 0 0 0 71 0 0 0 0 0 0 0 0 0 0 0.40 0.15 150 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.62 0.15 151 D -2 -2 1 7 -4 -1 1 -2 -1 -4 -4 -1 -4 -4 -2 0 -1 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.05 0.07 152 S 2 -1 0 -1 -1 0 -1 0 -1 -3 -3 -1 -2 -3 -1 4 1 -3 -2 -2 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0.47 0.07 153 Q -1 1 0 -1 -3 6 2 -2 0 -3 -3 1 -1 -4 -2 0 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.78 0.07 K Lambda Standard Ungapped 0.1333 0.3189 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1572 0.3177 PSI Gapped 0.0481 0.2670