Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.64 0.08 2 L 0 -2 -1 -2 -1 -1 -2 -2 -2 0 3 -1 1 -1 -2 3 0 -2 -2 0 0 0 0 0 0 0 0 0 0 0 52 0 0 0 0 48 0 0 0 0 0.25 0.08 3 P -1 -2 -2 -2 -3 -2 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.14 0.08 4 E -1 0 -1 1 -4 2 5 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.85 0.08 5 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.52 0.08 6 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.04 0.08 7 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.52 0.08 8 I -1 -3 -2 -3 -1 -2 -3 -3 -3 4 1 -2 1 -1 -3 -1 2 -3 -2 2 0 0 0 0 0 0 0 0 0 76 0 0 0 0 0 0 24 0 0 0 0.36 0.08 9 F 0 -2 -1 -2 -2 -2 -2 -2 -1 -1 -1 -2 -1 5 -2 3 0 -1 1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 52 0 48 0 0 0 0 0.39 0.08 10 D -2 -2 1 6 -4 -1 1 -2 -1 -3 -4 -1 -3 -4 -2 0 -1 -5 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.07 0.08 11 P -1 -2 -2 -2 -3 -2 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.14 0.08 12 L -1 -2 -2 -2 -1 -2 -2 -3 -3 2 2 -2 1 -1 -2 0 3 -3 -2 1 0 0 0 0 0 0 0 0 0 26 27 0 0 0 0 0 48 0 0 0 0.29 0.08 13 V 0 -3 -3 -3 -1 -2 -3 -3 -3 2 1 -3 0 -1 -3 -2 0 -3 -1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.47 0.08 14 D -2 -2 1 6 -4 -1 1 -2 -1 -3 -4 -1 -3 -4 -2 0 -1 -5 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.07 0.08 15 V 0 -3 -3 -3 -1 -2 -3 -3 -3 2 1 -3 0 -1 -3 -2 0 -3 -1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.47 0.08 16 L -1 -2 -3 -4 -2 -1 -2 -3 -2 1 3 -2 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 27 0 73 0 0 0 0 0 0 0 0.48 0.08 17 P -1 -2 -2 -2 -3 -2 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.14 0.08 18 V -1 -3 -3 -3 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 73 0 0 0 0 0 0 0 0 0 27 0.48 0.08 19 I -1 -3 -2 -3 -1 -2 -3 -3 -3 4 1 -2 1 -1 -3 -1 2 -3 -2 2 0 0 0 0 0 0 0 0 0 76 0 0 0 0 0 0 24 0 0 0 0.36 0.08 20 P -1 -2 -2 -2 -3 -2 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.14 0.08 21 V 0 -2 -2 -3 -1 -2 -2 -3 -3 1 3 -2 1 -1 -2 1 0 -2 -2 2 0 0 0 0 0 0 0 0 0 0 48 0 0 0 0 26 0 0 0 27 0.24 0.08 22 L -1 -2 -2 -3 -1 -2 -2 -3 -2 1 4 -2 1 0 -2 1 -1 -2 -1 0 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 26 0 0 0 0 0.32 0.08 23 F -1 -2 -2 -2 -2 -2 -1 -2 -2 -2 -2 -1 -2 3 6 1 -1 -2 0 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 27 48 26 0 0 0 0 0.82 0.08 24 L -1 -2 -2 -2 -2 -2 -2 -2 -2 -1 1 -2 0 3 4 1 -1 -2 0 -1 0 0 0 0 0 0 0 0 0 0 27 0 0 24 26 24 0 0 0 0 0.38 0.08 25 A 1 -2 -3 -3 -2 -2 -2 -2 -3 0 2 -2 0 -1 4 -1 -1 -3 -2 0 27 0 0 0 0 0 0 0 0 0 48 0 0 0 26 0 0 0 0 0 0.42 0.08 26 L -2 -2 -3 -3 -2 -2 -3 -4 -3 1 4 -2 1 0 4 -2 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 76 0 0 0 24 0 0 0 0 0 0.55 0.08 27 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.52 0.08 28 F -2 -3 -3 -3 -3 -2 -2 -3 -2 -1 1 -2 0 3 6 -2 -2 -2 0 -1 0 0 0 0 0 0 0 0 0 0 26 0 0 27 48 0 0 0 0 0 0.82 0.08 29 V 0 -3 -3 -3 -1 -2 -3 -3 -3 2 1 -3 0 -1 -3 -2 0 -3 -1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.47 0.08 30 W -3 2 -3 -4 -3 -1 -2 -3 -2 -3 -2 -1 -2 0 -4 -2 -2 10 1 -3 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76 0 0 1.78 0.08 31 Q -1 1 0 -1 -3 6 2 -2 0 -3 -2 1 -1 -3 -2 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.79 0.08 32 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.52 0.08 33 A 2 -2 -1 -1 -2 -1 -1 -1 -2 -2 -3 -1 -2 -3 6 2 0 -3 -3 -2 27 0 0 0 0 0 0 0 0 0 0 0 0 0 48 26 0 0 0 0 0.88 0.08 34 V 0 -3 -3 -3 -1 -2 -3 -3 -3 2 1 -3 0 -1 -3 -2 0 -3 -1 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.47 0.08 35 G 0 -2 0 -1 -2 -1 -1 4 -2 -3 -3 -1 -2 -3 -2 3 0 -3 -3 -3 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 50 0 0 0 0 0.61 0.08 36 F 0 -2 -1 -2 -2 -2 -2 -2 -1 -1 -1 -2 -1 5 -2 3 0 -1 1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 52 0 48 0 0 0 0 0.39 0.08 37 R -2 6 -1 -2 -4 1 0 -3 0 -3 -2 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.89 0.08 K Lambda Standard Ungapped 0.1500 0.3343 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1368 0.3061 PSI Gapped 0.0419 0.2670