Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 T 1 -2 -1 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 2 4 -3 -2 1 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 63 0 0 11 0.39 0.08 2 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.63 0.09 3 T 1 -2 -1 -2 -1 -1 -1 -2 -2 0 -1 -1 -1 -2 -2 1 5 -3 -2 1 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 0 0 13 0.46 0.10 4 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 2 1 0 -3 -2 -1 92 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0.52 0.10 5 H -2 2 0 -2 -3 0 -1 -3 8 -1 -2 -1 -2 -1 -3 -1 -2 -2 2 -2 0 13 0 0 0 0 0 0 72 8 0 0 0 0 0 0 0 0 6 0 0.73 0.10 6 S 2 -1 0 -1 -1 -1 -1 -1 -2 -3 -3 -1 -2 0 1 4 1 -3 -2 -2 15 0 0 0 0 0 0 0 0 0 0 0 0 5 7 74 0 0 0 0 0.48 0.15 7 D -2 -2 3 6 -4 -1 1 -2 -1 -4 -4 -1 -3 -4 -2 0 0 -5 -3 -3 0 0 21 75 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 0.93 0.16 8 Y -2 -2 -2 -1 -3 -2 -2 -4 1 -2 -2 -2 -2 3 -3 -2 -2 2 8 -2 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94 0 1.09 0.16 9 E -2 0 0 3 -4 1 5 -2 -1 -4 -4 1 -3 -4 -2 -1 -1 -4 -3 -3 0 4 0 20 0 0 70 0 0 0 0 5 0 0 0 0 0 0 0 0 0.77 0.16 10 I -2 -3 -4 -4 -2 -3 -4 -4 -4 5 2 -3 1 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 75 20 0 0 0 0 0 0 0 0 4 0.57 0.16 11 I -2 -3 -2 2 -2 -3 -2 -4 -3 4 0 -3 0 -1 -3 -2 -1 -4 -2 3 0 0 0 20 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 20 0.41 0.16 12 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.69 0.16 13 E -2 -1 0 3 -4 2 5 -2 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 20 0 11 69 0 0 0 0 0 0 0 0 0 0 0 0 0 0.80 0.16 14 G 0 -2 -1 -1 -2 -2 -2 6 -2 -3 -3 -1 -2 -3 -2 -1 -2 -2 -3 -3 2 1 1 1 0 1 1 81 0 1 2 1 0 1 1 1 1 0 1 1 0.88 0.12 15 G 0 -2 -1 -1 -2 -2 -2 6 -2 -3 -3 -1 -2 -3 -2 -1 -2 -2 -3 -3 2 1 1 1 0 1 1 81 0 1 2 1 0 1 1 1 1 0 1 1 0.88 0.12 16 S 2 -1 0 -1 -1 -1 -1 -1 -2 -2 -3 -1 -2 -3 -1 4 2 -3 -2 -2 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66 9 0 0 0 0.51 0.16 17 S 1 -1 0 -1 -1 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 3 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 20 0 0 0 0.59 0.16 18 S 0 -2 0 -1 -2 -1 -1 2 -2 -3 -3 -1 -2 -3 -2 4 2 -3 -2 -2 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 71 9 0 0 0 0.54 0.16 19 W -3 -3 -4 -5 3 -3 -3 -1 -3 -3 -2 -4 -2 0 -4 -3 -3 11 1 -3 0 0 0 0 11 0 0 5 0 0 0 0 0 0 0 0 0 84 0 0 2.19 0.16 20 G 0 -3 -1 -1 -3 -2 0 6 -2 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 11 89 0 0 0 0 0 0 0 0 0 0 0 0 1.08 0.16 21 Q -1 1 -1 -1 -3 4 1 -2 -1 -3 -3 4 -1 -4 -2 0 2 -3 -2 -2 0 0 0 0 0 35 0 0 0 0 0 46 0 0 0 0 20 0 0 0 0.52 0.16 22 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 2 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 16 20 0 0 0 0 0 0 0 0 65 0.50 0.16 23 K -1 3 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 20 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0.73 0.16 24 G 3 -2 -1 -2 -2 -2 -2 5 -2 -3 -3 -2 -2 -3 -2 0 -1 -3 -3 -2 44 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.16 25 R -2 6 -1 -1 -4 1 2 -3 -1 -3 -3 1 -2 -3 -2 -1 1 -3 -2 -3 0 70 0 0 0 0 20 0 0 0 0 0 0 0 0 0 11 0 0 0 0.70 0.16 26 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 2 0 -3 -2 -1 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0.58 0.16 27 K -1 4 1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 30 9 0 0 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0 0.65 0.16 28 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 71 0.56 0.16 29 N -2 -1 7 1 -3 0 -1 -1 0 -4 -4 -1 -3 -4 -3 0 0 -4 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.02 0.16 30 V 0 -3 -3 -4 -1 -3 -3 -3 -4 2 0 -3 0 -1 -3 -2 -1 -3 -2 5 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92 0.53 0.16 31 P -1 -3 -3 -2 -3 -2 -2 -3 -3 -3 -3 -2 -3 -4 8 -1 -2 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.23 0.16 32 A 2 -2 -2 -2 -2 -1 -1 -2 -2 -2 0 -1 -1 -3 5 2 -1 -3 -3 -2 29 0 0 0 0 0 0 0 0 0 11 0 0 0 41 20 0 0 0 0 0.72 0.16 33 A 5 0 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 95 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.58 0.16 34 I -1 1 -1 -2 -2 -1 -2 -2 -2 2 1 -1 0 -2 0 3 0 -3 -2 0 0 11 0 0 0 0 0 0 0 21 21 0 0 0 5 42 0 0 0 0 0.20 0.16 35 P -1 1 -2 -2 -3 -1 -2 -3 -2 -3 -3 -1 -3 -4 8 -1 -2 -4 -3 -3 0 11 0 0 0 0 0 0 0 0 0 0 0 0 89 0 0 0 0 0 1.91 0.16 36 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -1 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 95 0 0 0 0 5 0 0 0 0 0.61 0.16 37 L -2 -2 -3 -4 -2 -2 -3 -4 2 1 4 -3 1 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 11 0 89 0 0 0 0 0 0 0 0 0 0.57 0.16 38 P -1 -3 -2 -2 -3 -2 -2 -2 -3 -3 -3 -1 -3 -4 8 0 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89 11 0 0 0 0 1.92 0.16 39 T 4 -2 -2 -2 -1 -2 -2 -1 -2 2 -1 -2 -1 -2 -2 0 2 -3 -2 0 59 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 21 0 0 0 0.35 0.16 40 D 0 -2 1 6 -4 -1 1 -2 -2 -4 -4 -1 -3 -4 -2 -1 -1 -5 -4 -3 11 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.01 0.16 41 C -1 -4 -3 -4 9 -3 -4 2 -3 -2 -2 -3 -2 -3 -3 -1 -2 -3 -3 -2 0 0 0 0 80 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 1.27 0.16 42 N -2 -1 6 3 -4 0 2 -1 0 -4 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 66 15 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.16 43 I -1 -3 -4 -4 -2 -3 -3 -4 -4 4 2 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 38 20 0 0 0 0 0 0 0 0 42 0.50 0.16 44 R -1 3 -1 -1 -4 1 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -4 -2 -3 0 12 0 0 0 0 0 0 0 0 0 88 0 0 0 0 0 0 0 0 0.74 0.16 45 I -2 -3 -4 -4 -2 -3 -4 -4 -4 4 3 -3 2 0 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 50 35 0 5 0 0 0 0 0 0 11 0.50 0.16 46 D -2 0 4 3 -4 0 3 -2 -1 -4 -4 2 -3 -4 -2 0 -1 -4 -3 -3 0 0 32 20 0 0 29 0 0 0 0 19 0 0 0 0 0 0 0 0 0.57 0.16 47 A 4 -2 -3 -3 -1 -2 -2 -1 -3 0 -1 -2 2 -2 -2 0 -1 -3 -2 3 58 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 32 0.35 0.16 48 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.77 0.16 49 P -1 -1 -2 -2 -3 -1 -1 -3 -2 -3 -3 2 -3 -4 7 -1 -2 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 20 0 0 80 0 0 0 0 0 1.68 0.16 50 L -2 -3 -4 -4 -2 -3 -4 -4 -4 3 4 -3 1 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 29 71 0 0 0 0 0 0 0 0 0 0.58 0.16 51 D -1 -1 0 5 -3 0 2 1 -1 -3 -3 -1 -2 -3 -1 -1 -1 -3 -2 -3 2 1 1 62 0 1 12 10 0 1 2 1 0 1 1 1 1 0 1 1 0.63 0.13 52 A 2 -2 -1 -2 3 -1 -1 -1 -2 -2 -2 -1 -2 -2 5 1 0 -2 -2 -1 27 1 1 1 11 1 1 1 0 1 2 1 0 1 33 10 5 0 1 1 0.55 0.13 53 Q 3 -1 -1 -1 -2 4 2 -1 -1 -3 -3 0 -2 -3 1 1 -1 -3 -2 -2 37 0 0 0 0 29 20 0 0 0 0 0 0 0 5 9 0 0 0 0 0.41 0.16 54 K -1 1 2 3 -4 1 0 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -4 -3 -3 0 0 9 20 0 0 0 0 0 0 0 71 0 0 0 0 0 0 0 0 0.60 0.16 55 G -1 -3 0 3 -3 -2 -1 5 -2 -4 -4 -2 -3 -4 -3 -1 -2 -4 -4 -4 0 0 0 29 0 0 0 71 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.16 56 V -1 -3 -4 -4 -2 -3 -3 -4 -3 2 1 -3 0 4 -3 -2 -1 -2 0 4 0 0 0 0 0 0 0 0 0 0 11 0 0 27 0 0 0 0 0 63 0.46 0.16 57 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.60 0.16 58 R -2 7 -1 -2 -4 1 -1 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.16 59 F -2 -3 -4 -4 -2 -3 -4 -4 -3 2 2 -3 1 5 -4 -3 -2 -1 1 0 0 0 0 0 0 0 0 0 0 20 30 0 0 50 0 0 0 0 0 0 0.58 0.16 60 T 0 -2 0 -1 -1 -1 -1 -2 -2 -2 -2 -1 -1 -3 -2 3 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 27 73 0 0 0 0.60 0.16 61 T 2 -2 -1 -2 3 -2 -2 -1 -2 -2 -2 -2 -1 3 -2 2 2 -2 -1 -1 32 0 0 0 9 0 0 0 0 0 0 0 0 20 0 24 16 0 0 0 0.30 0.16 62 K 0 -1 -2 -2 -2 2 -1 -3 -2 0 -1 1 2 3 -2 -1 0 -2 0 2 5 0 0 0 0 16 0 0 0 0 0 16 9 20 0 4 4 0 0 27 0.16 0.16 63 I -2 -3 -3 -3 -2 -3 -4 2 -3 5 1 -3 0 1 -3 -2 -1 -3 -1 1 0 0 0 0 0 0 0 20 0 73 0 0 0 8 0 0 0 0 0 0 0.41 0.16 64 E -1 0 -1 1 -4 3 5 -3 0 -4 -3 0 -2 -4 -2 -1 -1 -3 -2 -3 0 0 0 0 0 20 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0.86 0.16 65 S 1 -1 0 -1 -1 -1 -1 -1 -1 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0.62 0.16 66 V 0 -3 -4 -4 -2 -3 -3 -4 -4 5 1 -3 1 -1 -3 -2 -1 -3 -2 3 9 0 0 0 0 0 0 0 0 79 0 0 0 0 0 0 0 0 0 12 0.52 0.16 67 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.60 0.16 68 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.16 69 S 1 -2 0 -1 -2 -1 -1 2 -2 -3 -3 -1 -2 -3 -2 5 1 -3 -2 -2 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 80 0 0 0 0 0.58 0.16 70 V -1 -2 -1 -2 -1 -2 -2 -3 -3 2 -1 -2 0 -2 -2 0 5 -3 -2 2 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 68 0 0 12 0.46 0.16 71 K -1 1 -1 -2 -3 0 0 -3 -2 0 1 5 -1 -2 -2 -1 -1 -3 -2 -1 0 0 0 0 0 0 0 0 0 9 20 71 0 0 0 0 0 0 0 0 0.41 0.16 72 N -2 -1 6 0 -3 -1 -1 2 0 -4 -4 1 -3 -4 -2 0 -1 -4 -3 -3 0 0 71 0 0 0 0 20 0 0 0 9 0 0 0 0 0 0 0 0 0.74 0.16 73 T -1 3 2 -1 -3 0 0 -2 -1 -3 -3 4 -2 -3 -2 0 2 -3 -2 -2 0 20 11 0 0 0 0 0 0 0 0 50 0 0 0 0 20 0 0 0 0.48 0.16 74 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 1 0 -3 -3 -1 -2 -2 2 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 20 0.57 0.16 75 N 1 -1 2 -1 -2 0 2 -2 -1 -1 -2 0 -1 -3 -2 1 2 -3 -2 1 16 0 12 0 0 0 24 0 0 0 0 4 0 0 0 9 15 0 0 21 0.21 0.16 76 V -1 -3 -3 -3 -2 -3 -3 2 -4 3 0 -3 0 -2 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 20 0 15 0 0 0 0 0 0 0 0 0 65 0.40 0.16 77 E -1 -1 -1 1 -4 2 6 -3 -1 -4 -3 0 -3 -4 -2 -1 -1 -3 -3 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.16 78 V 3 -2 -2 -2 -1 -2 -2 -1 -3 0 -1 -2 -1 -2 -2 2 0 -3 -2 3 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 40 0.31 0.16 79 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.16 80 I -2 -4 -4 -4 -2 -3 -4 -4 -4 6 1 -3 1 -1 -3 -3 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0.67 0.16 81 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.63 0.16 82 N -2 -1 7 1 -3 0 -1 -1 0 -4 -4 -1 -3 -4 -3 0 0 -4 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.02 0.16 83 E -1 -1 -1 1 -4 2 6 -3 -1 -4 -3 0 -3 -4 -2 -1 -1 -3 -3 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.16 84 T 0 -2 0 -1 -1 -1 -1 -2 -2 -2 -2 -1 -1 -3 -2 3 5 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 71 0 0 0 0.59 0.16 85 K -1 1 -1 -1 -3 0 0 -2 -1 -3 -3 5 -2 -4 4 1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 67 0 0 20 13 0 0 0 0 0.64 0.16 86 D -2 -2 0 5 -3 0 3 -2 -1 -3 -3 -1 -3 -4 -2 0 2 -4 -3 -3 0 0 0 54 0 0 27 0 0 0 0 0 0 0 0 0 20 0 0 0 0.70 0.16 87 R -2 6 -1 -2 -4 0 -1 0 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 89 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 0 0 0 0.87 0.16 88 R -2 7 -1 -2 -4 1 -1 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.16 89 I -1 -3 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 38 0.57 0.16 90 A 4 -2 -1 -2 4 -1 -1 -1 -2 -2 -2 -1 -2 -3 -1 3 0 -3 -2 -1 59 0 0 0 12 0 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0.48 0.16 91 V 2 -3 -3 -3 -1 -2 -3 -3 -3 2 0 -2 0 -2 -3 -1 -1 -3 -2 5 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 0.45 0.16 92 G 0 -3 -1 0 -3 -2 -2 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 4 0 0 0 96 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.16 93 E -2 -1 0 3 -4 1 5 -3 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 20 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0.87 0.16 94 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.28 0.16 95 S -1 0 -1 -1 -2 0 3 -2 -1 -1 -1 2 2 -3 -2 2 0 -3 -2 0 0 0 0 0 0 0 25 0 0 0 0 24 15 0 0 28 0 0 0 9 0.27 0.16 96 L -1 -3 -4 -4 -1 -3 -3 -4 -4 3 2 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 20 20 0 0 0 0 0 0 0 0 60 0.49 0.16 97 S 0 -1 0 -1 -1 -1 -1 -1 -2 -2 -2 -1 -2 -3 -1 4 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0.55 0.16 98 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 0 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.60 0.16 99 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.26 0.14 100 D -2 -1 1 6 -4 0 1 -2 -1 -4 -4 2 -3 -4 -2 -1 -1 -5 -3 -4 0 0 0 79 0 0 0 0 0 0 0 21 0 0 0 0 0 0 0 0 0.89 0.14 101 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.04 0.14 102 S 1 -1 0 -1 -1 -1 -1 -1 -1 -3 -3 -1 -2 -3 -1 5 2 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95 5 0 0 0 0.62 0.14 103 H -2 -1 0 -2 1 0 -1 -3 9 -4 -3 -1 -2 -2 -3 -1 -2 -3 1 -4 0 0 0 0 6 0 0 0 94 0 0 0 0 0 0 0 0 0 0 0 1.13 0.14 104 S 1 3 0 -1 -2 0 0 -2 -1 -3 -3 3 -2 -3 -2 3 2 -3 -2 -2 8 21 0 0 0 0 0 0 0 0 0 24 0 0 0 33 14 0 0 0 0.37 0.14 105 F -3 -3 -4 -4 -3 -4 -4 -4 -2 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0 0 0 1.20 0.10 335 A 4 3 -1 -2 -1 0 -1 -1 -2 -2 -2 0 -1 -3 -2 0 1 -3 -2 -1 61 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0.36 0.10 336 Y -2 -2 -3 -4 -3 -2 -2 -4 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.09 0.10 337 A 4 0 -1 -2 -1 0 -1 -1 -2 -2 -2 2 -1 -3 -1 1 -1 -3 -2 -1 73 0 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0.40 0.10 338 R 2 5 -1 -2 -3 0 0 -2 -1 -3 -2 2 -2 -3 -2 0 -1 -3 -2 -2 27 61 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0.54 0.10 339 W -3 -3 -4 -5 -3 -2 -3 -3 -3 -3 -2 -3 -2 1 -4 -3 -3 11 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.57 0.10 340 V 3 -2 -3 -3 -1 -2 -2 -2 -3 1 0 -2 0 -2 -2 -1 0 -3 -2 4 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61 0.33 0.10 341 E -1 0 -1 1 -4 2 6 -3 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.89 0.10 342 H -1 -1 0 -2 -3 0 -1 3 8 -4 -3 -1 -2 -2 -3 -1 -2 -3 1 -4 0 0 0 0 0 0 0 27 73 0 0 0 0 0 0 0 0 0 0 0 0.83 0.10 343 V -1 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 73 0.48 0.10 344 C -1 -4 -3 -4 10 -3 -4 -3 -3 -2 -2 -4 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.50 0.10 345 K -1 2 -1 -1 -3 1 0 -2 -1 -3 -3 5 -2 -3 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 0.55 0.10 346 G 0 -3 -1 -2 -3 -2 -3 6 -2 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.19 0.10 347 G 0 -2 0 -1 -2 -2 -2 5 -2 -4 -4 -1 -3 -3 -2 2 -1 -3 -3 -3 0 0 0 0 0 0 0 72 0 0 0 0 0 0 0 28 0 0 0 0 0.81 0.10 348 T -1 -2 -1 -2 -2 -2 -2 -3 -1 0 -1 -2 -1 0 -2 0 4 -1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53 0 27 20 0.37 0.11 349 G 0 -2 0 -1 -2 -2 -2 5 -2 -4 -4 -1 -3 -3 -2 2 -1 -3 -3 -3 0 0 0 0 0 0 0 71 0 0 0 0 0 0 0 29 0 0 0 0 0.81 0.11 350 Q -1 0 -1 -1 -3 5 1 -2 0 -3 -3 1 -1 -4 4 -1 -1 -3 -2 -3 0 0 0 0 0 71 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0.85 0.11 351 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.97 0.11 352 E -2 -1 0 5 -4 1 4 -2 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 46 0 0 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0.81 0.11 353 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0 0 39 0.50 0.11 354 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 1 4 -4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 71 0 0 29 0 0 0 0 0 0 0.53 0.11 355 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -1 -1 -3 -1 5 -4 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 29 0 0 0 0 71 0 0.94 0.11 356 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.05 357 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 -1 -4 -2 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.05 K Lambda Standard Ungapped 0.1370 0.3179 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1566 0.3176 PSI Gapped 0.0479 0.2670