Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 S 1 -1 0 -1 -1 -1 -1 -1 -1 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.67 0.16 2 R -2 7 -1 -2 -4 1 -1 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.16 3 D -2 0 0 6 -4 0 1 -2 -1 -4 -4 3 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 68 0 0 0 0 0 0 0 32 0 0 0 0 0 0 0 0 0.81 0.16 4 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.09 0.16 5 R -1 2 -1 -2 -2 0 -1 -2 -2 -1 -2 3 -1 -3 -2 0 3 -3 -2 1 0 16 0 0 0 0 0 0 0 0 0 36 0 0 0 0 32 0 0 17 0.34 0.16 6 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -2 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.22 0.16 7 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.28 0.16 8 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.16 9 V -1 -2 -1 -2 -1 -1 -2 -2 -2 0 -1 -1 -1 -2 -2 1 5 -3 -2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84 0 0 16 0.59 0.16 10 P -1 -3 -3 -2 -3 -2 -2 -3 -3 -3 -3 -2 -3 -4 8 -1 -2 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.23 0.16 11 N -2 -1 6 0 -3 -1 -1 3 0 -4 -4 -1 -3 -4 -3 0 -1 -4 -3 -4 0 0 79 0 0 0 0 21 0 0 0 0 0 0 0 0 0 0 0 0 0.97 0.26 12 R -2 5 -2 -2 -3 3 -1 -3 -1 -2 2 0 0 -2 -3 -2 -2 -3 -2 -2 0 49 0 0 0 21 0 0 0 0 30 0 0 0 0 0 0 0 0 0 0.56 0.26 13 A 3 -2 -1 -2 -2 -1 -1 -2 6 -2 -2 -1 -2 -3 -2 0 3 -3 -1 -1 33 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 38 0 0 0 0.54 0.26 14 V -2 -3 -4 -4 -2 -3 -4 -5 -4 4 4 -3 1 -1 -4 -3 -2 -3 -2 2 0 0 0 0 0 0 0 0 0 34 54 0 0 0 0 0 0 0 0 11 0.62 0.26 15 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.34 0.26 16 V -1 -3 -2 -3 -2 -2 -3 -3 -3 1 0 -2 0 -2 -3 -1 3 -4 -2 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33 0 0 67 0.55 0.26 17 F 0 -3 -3 -3 -3 -3 -3 -3 -2 -1 -1 -3 -1 7 -3 1 -2 0 2 -2 13 0 0 0 0 0 0 0 0 0 0 0 0 74 0 13 0 0 0 0 0.78 0.26 18 F -2 3 -2 -3 -3 -1 -2 -3 -2 0 0 -1 7 2 -3 -2 -2 -2 -1 -1 0 30 0 0 0 0 0 0 0 0 0 0 59 11 0 0 0 0 0 0 0.61 0.26 19 D -1 -3 -1 1 -3 -2 -2 6 -3 -4 -4 -2 -3 -4 -3 1 -2 -4 -4 -4 0 0 0 11 0 0 0 77 0 0 0 0 0 0 0 11 0 0 0 0 1.01 0.26 20 T -1 -2 -1 -2 -2 -2 -2 -3 -3 0 -1 -2 -1 -2 -2 0 5 -3 -2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 0 0 28 0.63 0.26 21 N -2 -2 4 6 -4 -1 0 -2 -1 -4 -4 -1 -3 -4 -2 1 -1 -5 -3 -4 0 0 26 62 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0.92 0.26 22 G -1 -3 -1 -2 -3 -3 -3 6 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.42 0.26 23 V -1 -3 -4 -4 -2 -3 -3 -4 -4 3 0 -3 0 -1 -3 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 21 0 0 0 0 0 0 0 0 0 79 0.70 0.26 24 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -4 -3 -2 -2 -4 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.20 0.26 25 T -1 -2 2 -1 -2 -1 -1 -2 5 -2 -3 -1 -2 -3 -2 0 5 -3 -1 -2 0 0 10 0 0 0 0 0 26 0 0 0 0 0 0 0 63 0 0 0 0.67 0.26 26 V -1 -4 -4 -4 -2 -3 -4 -4 -4 4 0 -3 0 -1 -3 -3 -1 -4 -2 5 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 64 0.68 0.26 27 P -1 -1 -1 -1 -3 4 2 -3 -1 -4 -3 -1 -2 -4 6 1 -1 -4 -3 -3 0 0 0 0 0 30 13 0 0 0 0 0 0 0 44 13 0 0 0 0 0.98 0.26 28 A 4 -2 -2 -2 -1 -1 -2 -1 -2 -1 -2 -1 -2 -3 -2 3 0 -3 -2 1 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 0 0 11 0.50 0.26 29 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.34 0.26 30 M -2 -3 -4 -4 -2 -3 -3 -4 -4 3 3 -3 3 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 15 34 0 11 0 0 0 0 0 0 39 0.53 0.26 31 E -2 2 -1 2 -3 0 3 -3 3 -3 -3 0 -2 -2 -2 -1 3 -2 2 -2 0 15 0 11 0 0 26 0 11 0 0 0 0 0 0 0 26 0 10 0 0.40 0.26 32 F -3 -4 -4 -4 -3 -4 -4 -4 -2 -1 1 -4 0 7 -4 -3 -3 0 2 -1 0 0 0 0 0 0 0 0 0 0 11 0 0 89 0 0 0 0 0 0 1.12 0.26 33 T -1 -2 0 4 -2 -1 0 -2 -2 -3 -3 -1 -2 -4 -2 2 3 -4 -3 -2 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 26 33 0 0 0 0.62 0.26 34 G -2 -1 4 2 -4 0 4 2 -1 -4 -4 -1 -3 -4 -2 -1 -2 -4 -3 -4 0 0 26 11 0 0 40 22 0 0 0 0 0 0 0 0 0 0 0 0 0.63 0.26 35 D -2 -1 0 6 -4 -1 1 -2 -2 -3 -4 1 -3 -4 -2 -1 1 -5 -3 -3 0 0 0 70 0 0 0 0 0 0 0 15 0 0 0 0 15 0 0 0 0.87 0.26 36 L -1 -3 -3 -3 -2 -2 -3 -3 -3 1 1 -2 3 -2 -3 -1 3 -3 -2 4 0 0 0 0 0 0 0 0 0 0 11 0 11 0 0 0 25 0 0 52 0.44 0.26 37 G 1 -1 -1 -1 -3 2 2 1 -2 -2 0 1 -1 -3 -2 1 1 -3 -3 -2 11 0 0 0 0 13 15 11 0 0 15 10 0 0 0 13 11 0 0 0 0.20 0.26 38 L -2 -3 -4 -4 -2 -3 -4 -4 -3 1 1 -3 0 4 -4 -3 -1 -2 0 4 0 0 0 0 0 0 0 0 0 0 11 0 0 30 0 0 0 0 0 59 0.57 0.26 39 G -2 -2 2 2 -4 2 1 2 0 -3 -3 -1 -3 -1 -3 -1 -2 -1 4 -3 0 0 15 15 0 11 11 22 0 0 0 0 0 0 0 0 0 0 26 0 0.44 0.26 40 H -1 -1 3 -1 -3 0 -1 -2 7 -4 -4 2 -2 -3 -2 2 -1 -4 0 -3 0 0 15 0 0 0 0 0 46 0 0 15 0 0 0 25 0 0 0 0 0.69 0.26 41 V -2 -3 -4 -4 -2 -3 -4 -4 -4 1 4 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0 39 0.61 0.26 42 T 2 -2 -1 -2 -1 -1 -2 -2 -2 -2 -2 -1 -1 -3 -2 1 5 -3 -2 -1 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0.64 0.26 43 I -1 -2 -3 -3 -2 -2 -3 -3 -2 2 3 -2 0 0 -3 -2 -1 -1 3 3 1 1 1 1 0 1 1 1 0 12 37 1 0 1 1 1 1 0 13 26 0.34 0.22 44 R 1 2 0 3 -3 0 0 -2 3 -3 -3 2 -2 -3 -2 -1 -1 -3 -2 -2 16 12 1 27 0 1 1 1 12 1 1 22 0 1 1 1 1 0 0 1 0.35 0.22 45 A 3 -2 -2 -2 -2 -2 -2 3 -3 -1 -2 -2 -2 -3 -2 2 -1 -3 -3 1 44 0 0 0 0 0 0 26 0 0 0 0 0 0 0 15 0 0 0 15 0.45 0.26 46 S 1 -2 -1 -2 -2 -2 -2 1 -2 -2 -2 -2 -2 2 -2 3 3 -2 -1 -2 15 0 0 0 0 0 0 11 0 0 0 0 0 15 0 33 26 0 0 0 0.36 0.26 47 T -1 -1 -1 -2 -2 3 -1 -3 -2 -1 -2 -1 -1 -3 -2 0 5 -3 -2 1 0 0 0 0 0 26 0 0 0 0 0 0 0 0 0 0 59 0 0 15 0.53 0.26 48 S 0 -1 -1 -1 -2 3 0 -2 -1 -2 -2 -1 -2 -3 -2 4 0 -3 -2 1 0 0 0 0 0 26 0 0 0 0 0 0 0 0 0 59 0 0 0 15 0.48 0.26 49 S 2 -2 -1 -2 -2 -1 -2 3 -2 -2 -2 -2 3 -3 -2 3 0 -3 -3 -2 21 0 0 0 0 0 0 26 0 0 0 0 15 0 0 37 0 0 0 0 0.44 0.26 50 N 2 2 4 -1 -3 4 0 -2 -1 -3 -3 0 -2 -4 -2 0 -1 -4 -3 -3 26 15 33 0 0 26 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.49 0.26 51 I -1 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 0 -1 -3 -3 -1 -4 -2 4 0 0 0 0 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0 53 0.68 0.26 52 R -2 6 -1 -2 -4 3 -1 -3 -1 -2 0 1 -1 -3 -3 -2 -2 -3 -2 -2 0 70 0 0 0 15 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0.77 0.26 53 S 3 -1 -1 -1 -1 -1 -1 -1 -2 -2 -2 2 -2 -3 -1 3 0 -3 -2 -1 40 1 1 1 0 1 1 1 0 1 1 16 0 1 1 34 1 0 0 1 0.38 0.22 54 E -1 2 -1 0 -3 0 4 -2 -1 1 -2 0 -1 -2 -2 1 -1 -3 -2 -1 1 14 1 1 0 1 45 1 0 16 1 1 0 1 1 16 1 0 0 1 0.36 0.22 55 V -1 -2 -2 -3 -2 -2 -2 -3 -2 2 2 -2 4 -1 -2 1 -1 -2 -2 2 1 1 1 1 0 1 1 1 0 14 16 1 22 0 1 16 1 0 0 24 0.28 0.22 56 L 1 0 -1 -2 -2 2 0 -2 -2 -1 1 4 -1 -2 -2 -1 -1 -3 -2 -1 16 1 1 1 0 11 1 1 0 1 24 40 0 0 1 1 1 0 0 1 0.27 0.22 57 M 1 -2 -3 -3 -2 -2 -3 -3 -3 0 2 -2 5 2 -3 -1 1 -2 -1 0 15 0 0 0 0 0 0 0 0 0 25 0 33 13 0 0 15 0 0 0 0.38 0.26 58 E -1 -2 -1 4 -4 0 4 3 -2 -4 -4 -1 -3 -4 -2 -1 -2 -4 -3 -4 0 0 0 26 0 0 44 30 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.26 59 G 1 1 -1 1 -3 -2 -2 5 -3 -4 -4 -2 -3 -4 -3 -1 -2 -4 -4 -3 12 9 0 12 0 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0.87 0.30 60 E -2 -2 4 5 -4 0 3 -2 -1 -4 -4 -1 -3 -4 -2 -1 -2 -5 -3 -4 0 0 28 47 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0.90 0.30 61 Y 1 -3 -3 -4 -3 -2 -3 -3 1 -2 -2 -2 -2 2 -3 -2 -2 1 8 -2 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81 0 1.12 0.30 62 G 2 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -3 22 0 0 0 0 0 0 78 0 0 0 0 0 0 0 0 0 0 0 0 1.11 0.30 63 F -2 -3 -4 -4 -2 -3 -4 -4 -3 2 3 -3 5 4 -4 -3 -2 -2 0 1 0 0 0 0 0 0 0 0 0 9 30 0 24 25 0 0 0 0 0 12 0.56 0.30 64 I -1 -3 -3 -3 -2 -3 -3 -3 -2 4 0 -3 -1 0 -3 1 -1 -1 4 2 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 19 0 0 24 12 0.46 0.30 65 G 2 -3 -1 -2 -3 -2 -2 5 -3 -4 -4 -2 -3 -4 -3 1 -2 -3 -4 -3 21 0 0 0 0 0 0 68 0 0 0 0 0 0 0 11 0 0 0 0 0.94 0.30 66 K -1 1 -1 -1 -3 3 0 -2 -1 -3 -3 5 -2 -3 -2 -1 1 -3 -2 -2 1 1 1 1 0 19 1 1 0 1 1 58 0 0 1 1 13 0 0 1 0.57 0.27 67 S -1 -1 2 2 -2 -1 -1 -2 -2 -2 -2 1 -2 -3 -2 2 4 -3 -2 -2 1 1 12 13 0 0 1 1 0 1 1 10 0 0 1 17 39 0 0 1 0.40 0.27 68 I -1 -3 -3 -3 -2 -2 -3 -3 -2 3 0 -3 0 -1 -3 -2 -1 -2 3 4 1 1 1 1 0 0 1 1 0 18 1 1 0 0 1 1 1 0 13 59 0.49 0.27 69 P -1 -3 -3 -2 -2 -2 -2 -3 -3 -1 0 -2 -1 -2 6 -2 -1 -3 -3 2 1 1 1 1 0 0 1 1 0 1 14 1 0 0 58 1 1 0 0 20 1.07 0.27 70 T -1 -1 2 -2 -2 -1 -2 -3 -2 3 -1 2 -1 -2 -2 1 3 -4 -3 0 0 0 12 0 0 0 0 0 0 30 0 17 0 0 0 9 31 0 0 0 0.33 0.30 71 D -2 -1 0 6 -4 -1 1 -2 -2 -4 -4 2 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 77 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 1.07 0.30 72 N -1 -1 4 2 -2 -1 -1 -2 -1 -3 -3 1 -2 -2 -2 2 1 -2 2 -2 1 1 29 10 0 1 1 1 0 1 1 9 0 0 1 20 12 0 12 1 0.36 0.27 73 P -1 -2 -2 -2 -2 -2 -2 -2 -2 -1 0 -2 -1 -3 6 2 -1 -3 -2 0 1 1 1 1 0 1 1 1 0 1 13 1 0 0 48 20 1 0 0 10 0.83 0.27 74 A 2 -2 2 -1 -2 -1 -1 -1 -2 -2 -2 -1 -2 -3 -1 3 3 -3 -2 -1 28 1 12 1 0 1 1 1 0 1 1 1 0 0 1 23 27 0 0 1 0.38 0.27 75 G 4 -2 -2 -3 -2 -2 -2 3 -3 -2 -2 1 -2 -3 -2 0 -1 -4 -3 1 48 0 0 0 0 0 0 28 0 0 0 12 0 0 0 0 0 0 0 12 0.47 0.30 76 Q -2 0 3 -1 -3 6 0 -2 -1 -3 -3 0 -2 -4 -2 0 2 -3 -3 -3 0 0 24 0 0 57 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0.73 0.30 77 R -2 6 -1 -2 -4 0 -1 2 -1 -4 -3 1 -2 -4 -3 -2 -2 -4 -3 -4 0 81 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0.99 0.30 78 I -2 -3 -4 -5 -2 -3 -4 -5 -4 2 5 -3 1 -1 -4 -3 -2 -3 -2 1 0 0 0 0 0 0 0 0 0 8 83 0 0 0 0 0 0 0 0 9 0.75 0.30 79 I -2 -2 -3 -3 -3 2 -2 -4 -1 5 0 -2 0 0 -3 -3 -2 -1 4 1 0 0 0 0 0 19 0 0 0 57 0 0 0 0 0 0 0 0 24 0 0.54 0.30 80 F -2 -3 -4 -4 -2 -3 -4 -4 -3 3 3 -4 0 4 -4 -3 -2 -2 0 2 0 0 0 0 0 0 0 0 0 17 36 0 0 27 0 0 0 0 0 20 0.57 0.30 81 C 0 -2 -1 -2 6 -2 -2 -2 -3 -2 1 -2 -1 -2 -2 4 0 -3 -3 -2 0 0 0 0 28 0 0 0 0 0 19 0 0 0 0 52 0 0 0 0 0.61 0.30 82 G 2 -3 -1 -2 -2 -2 -2 5 -3 -4 -4 -2 -3 -4 -2 2 -1 -3 -3 -3 19 0 0 0 0 0 0 60 0 0 0 0 0 0 0 21 0 0 0 0 0.83 0.30 83 G -1 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 2 -3 -4 -3 0 0 0 0 0 0 0 79 0 0 0 0 0 0 0 0 21 0 0 0 1.08 0.30 84 E 1 -1 -1 2 -3 0 4 0 5 -4 -4 -1 -3 -3 -2 -1 -2 -4 -2 -3 19 0 0 12 0 0 40 8 21 0 0 0 0 0 0 0 0 0 0 0 0.55 0.30 85 G -1 -1 -1 -2 -3 1 -1 4 -2 -3 -3 1 -2 -4 -2 0 4 -3 -3 -2 0 0 0 0 0 10 0 36 0 0 0 10 0 0 0 0 44 0 0 0 0.56 0.30 86 T 2 -2 -1 -2 -2 -2 -2 -2 -3 -2 -2 -2 -2 -3 2 0 5 -4 -3 -1 25 0 0 0 0 0 0 0 0 0 0 0 0 0 11 0 64 0 0 0 0.70 0.36 87 S 0 -2 3 -1 -2 -2 -2 2 -1 -3 -3 -2 -2 -2 -2 3 2 -3 2 -2 7 0 16 0 0 0 0 16 0 0 0 0 0 0 0 34 17 0 11 0 0.43 0.36 88 S 1 -2 -1 -2 -2 -2 -2 -2 -2 -1 -2 -2 -2 -3 -2 5 0 -4 -3 2 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66 0 0 0 28 0.55 0.36 89 T 1 -2 3 3 -3 2 0 -2 -2 -3 -3 -1 -2 -4 -2 2 2 -4 -3 -3 11 0 16 24 0 16 0 0 0 0 0 0 0 0 0 16 18 0 0 0 0.47 0.36 90 T 1 -2 3 4 -3 -2 -1 -2 -2 -3 -3 -2 -2 3 -3 1 2 -3 -1 -2 16 0 16 31 0 0 0 0 0 0 0 0 0 17 0 7 14 0 0 0 0.43 0.36 91 G -1 -3 3 -2 -4 -2 -3 6 -2 -5 -5 -2 -4 -4 -3 -1 -2 -4 -4 -4 0 0 17 0 0 0 0 83 0 0 0 0 0 0 0 0 0 0 0 0 1.26 0.36 92 A 3 -1 -1 -2 -2 -1 -1 -1 -2 -3 -3 2 -2 -3 -2 4 0 -4 -3 -2 41 0 0 0 0 0 0 0 0 0 0 17 0 0 0 42 0 0 0 0 0.56 0.36 93 Q -2 -2 -2 2 -3 3 -1 -3 -2 -1 3 -2 3 -2 -3 -2 2 -3 -2 -1 0 0 0 16 0 21 0 0 0 0 37 0 11 0 0 0 16 0 0 0 0.37 0.36 94 I -2 -4 -4 -4 -3 -4 -4 1 -4 5 2 -4 0 3 -4 -3 -2 -3 -1 1 0 0 0 0 0 0 0 15 0 52 18 0 0 15 0 0 0 0 0 0 0.56 0.39 95 T -2 2 -1 -1 -3 4 2 -3 -1 -3 -3 0 -2 -4 -2 0 4 -3 -3 -2 0 15 0 0 0 33 11 0 0 0 0 0 0 0 0 0 41 0 0 0 0.65 0.39 96 L -3 -3 -5 -5 -2 -3 -4 -5 -4 3 5 -4 1 -1 -4 -4 -2 -3 -2 0 0 0 0 0 0 0 0 0 0 15 85 0 0 0 0 0 0 0 0 0 0.88 0.39 97 Y 1 -2 -2 -3 -3 -1 -2 -3 7 -3 -3 -2 -2 0 -3 -1 2 -1 6 -2 15 0 0 0 0 0 0 0 35 0 0 0 0 0 0 0 15 0 35 0 0.82 0.39 98 G -1 -2 2 -1 -3 -2 -2 4 -1 -3 -3 -2 -3 -2 -2 1 -1 -2 3 -3 1 1 15 1 0 0 1 46 0 1 1 1 0 0 1 16 1 0 15 1 0.60 0.35 99 A 3 -2 -1 2 -2 -2 -1 -2 -2 -3 -3 -2 -2 -2 -2 3 1 -2 3 -2 35 0 0 15 0 0 0 0 0 0 0 0 0 0 0 25 11 0 15 0 0.44 0.39 100 N -2 2 6 0 -4 3 -1 0 -1 -4 -4 2 -3 -4 -3 -1 -1 -4 -3 -4 0 9 57 0 0 15 0 5 0 0 0 15 0 0 0 0 0 0 0 0 0.80 0.39 101 N -1 -2 3 2 -3 -1 -1 -2 5 -4 -4 -1 -3 -3 -2 3 2 -4 -2 -3 0 0 17 15 0 0 0 0 18 0 0 0 0 0 0 35 15 0 0 0 0.58 0.39 102 T 3 -2 -1 2 -2 -1 2 -2 -2 -3 -3 -1 -2 -4 -2 2 2 -4 -3 -2 35 0 0 15 0 0 15 0 0 0 0 0 0 0 0 21 15 0 0 0 0.46 0.39 103 D -2 -2 3 1 -3 -1 2 2 -2 -2 -3 -2 -2 -2 -3 -1 3 -3 2 0 0 0 21 6 0 0 15 15 0 0 0 0 0 0 0 0 23 0 9 11 0.34 0.39 104 S 0 1 -1 -2 -3 -2 -2 2 -2 -4 -4 -1 -3 -4 4 3 -1 -4 -3 -3 6 11 0 0 0 0 0 15 0 0 0 0 0 0 27 41 0 0 0 0 0.69 0.39 105 R -2 3 5 -1 -3 -1 -1 -2 -1 -3 -3 1 3 -3 -3 1 -1 -4 -3 -3 0 21 44 0 0 0 0 0 0 0 0 6 15 0 0 15 0 0 0 0 0.62 0.39 106 R -3 6 -2 -3 -4 -1 -2 -4 -2 1 1 0 -1 -3 -3 -2 -2 -4 -3 -2 0 70 0 0 0 0 0 0 0 15 15 0 0 0 0 0 0 0 0 0 0.82 0.39 107 I 3 -3 -4 -4 -2 -3 -3 -3 -3 3 -1 -3 -1 5 -3 -2 -2 -2 0 0 32 0 0 0 0 0 0 0 0 27 0 0 0 41 0 0 0 0 0 0 0.61 0.39 108 V -2 -3 -2 2 -2 -3 -2 -4 -4 3 1 -3 -1 -2 -3 -2 2 -4 -3 3 0 0 0 15 0 0 0 0 0 24 11 0 0 0 0 0 21 0 0 30 0.42 0.39 109 Y -2 -3 -3 -4 -3 -2 -3 -4 -1 -1 2 -3 2 1 -4 -2 2 0 7 -1 0 0 0 0 0 0 0 0 0 0 24 0 9 0 0 0 15 0 52 0 0.77 0.39 110 N -3 4 6 -1 -4 -1 -2 -2 0 -4 -4 0 -3 -2 -3 -1 -2 -2 4 -4 0 30 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18 0 0.83 0.39 111 G 5 -3 -2 -2 -2 -2 1 3 -3 -3 -3 -2 -3 -4 -2 0 -2 -4 -3 -2 69 0 0 0 0 0 11 21 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.47 112 D -2 -2 3 3 -4 2 2 -3 -2 -3 -1 -1 -2 -4 2 1 1 -4 -3 -3 0 0 20 16 0 10 14 0 0 0 9 0 0 0 11 10 11 0 0 0 0.42 0.47 113 E 2 -2 -2 -2 -3 2 3 4 -2 -4 -4 -1 -3 -4 -3 -1 -2 -4 -4 -3 24 0 0 0 0 10 23 42 0 0 0 0 0 0 0 0 0 0 0 0 0.69 0.47 114 H -2 -2 -1 1 -4 -2 -2 2 7 -4 -4 -2 -3 -1 -3 -2 1 -2 5 -3 0 0 0 11 0 0 0 21 34 0 0 0 0 0 0 0 10 0 24 0 0.77 0.47 115 L 2 2 -3 -4 -3 -2 -3 -3 -3 -2 2 1 -1 4 -3 -2 -2 -2 -1 -2 27 17 0 0 0 0 0 0 0 0 20 10 0 26 0 0 0 0 0 0 0.46 0.56 116 F -3 -4 -4 -5 -4 -4 -4 -5 -2 -1 -1 -4 4 7 -5 -4 -3 0 5 -2 0 0 0 0 0 0 0 0 0 0 0 0 17 61 0 0 0 0 22 0 1.28 0.56 117 Q -2 -2 3 1 -3 2 1 -3 -2 -3 0 -2 -2 -4 2 2 1 -4 -3 -1 0 0 17 8 0 12 8 0 0 0 10 0 0 0 10 18 11 0 0 5 0.34 0.56 118 S 2 -2 3 -2 -3 2 -2 2 -2 -4 -4 -2 -3 -3 -3 2 1 -3 2 -3 17 0 15 0 0 11 0 19 0 0 0 0 0 0 0 16 10 0 10 0 0.42 0.56 119 A 2 -3 3 -2 -3 1 -2 3 -2 1 -3 -2 -3 -4 -3 -1 1 -4 -3 -2 25 0 22 0 0 7 0 27 0 10 0 0 0 0 0 0 8 0 0 0 0.48 0.56 120 D 1 1 3 3 -3 -1 -1 -2 -2 -4 -4 -1 -3 -4 2 3 0 -4 -3 -3 10 8 17 19 0 0 0 0 0 0 0 0 0 0 8 37 0 0 0 0 0.47 0.29 121 V -2 -4 -4 -4 -2 -4 -4 -4 -3 4 0 -4 0 5 -4 -3 -2 -2 0 3 0 0 0 0 0 0 0 0 0 37 0 0 0 36 0 0 0 0 0 27 0.64 0.29 122 K -2 1 -2 -3 -3 -1 -2 -3 -2 1 1 2 5 -2 -3 0 -1 -3 -2 1 0 9 0 0 0 0 0 0 0 11 9 19 35 0 0 8 0 0 0 10 0.35 0.29 123 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -5 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.38 0.29 124 Y 0 -2 -2 -3 -2 -2 -2 -3 0 -1 -1 -2 2 1 -3 1 1 0 6 1 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 17 10 0 47 11 0.52 0.29 125 N 0 -2 2 -2 -2 -2 -2 -3 -2 0 2 -2 0 -2 -3 0 2 -3 -2 2 9 0 17 0 0 0 0 0 0 0 30 0 0 0 0 8 18 0 0 19 0.25 0.29 126 D -3 -2 1 7 -4 -1 1 -2 -2 -4 -5 -2 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.41 0.29 127 N -2 -1 7 0 -3 -1 -1 1 0 -4 -4 -1 -3 -4 -3 1 -1 -4 -3 -4 0 0 83 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 1.01 0.29 128 V 1 -2 1 -2 -2 3 -1 -2 -2 0 -1 -1 -1 -3 -3 -1 -1 -4 -2 4 17 0 11 0 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0.35 0.29 129 T -2 1 2 -2 -3 -2 -2 -3 -2 -1 -1 1 -1 3 -3 -1 2 -2 2 2 0 8 13 0 0 0 0 0 0 0 0 11 0 16 0 0 15 0 10 27 0.24 0.29 130 A 4 -2 -1 1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 2 3 1 -4 -3 -2 47 0 0 10 0 0 0 0 0 0 0 0 0 0 10 25 8 0 0 0 0.49 0.29 131 L 1 -3 -4 -4 -2 -3 -3 -3 -3 0 5 -3 1 -1 -3 -2 -2 -3 -2 0 18 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 0 0.63 0.29 132 G -1 -3 -1 -2 -3 -3 -3 6 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.46 0.29 133 G -1 0 -1 -2 -3 -2 -3 6 -3 0 -3 -2 -3 -4 -3 0 -2 -3 -4 -3 0 8 0 0 0 0 0 75 0 9 0 0 0 0 0 9 0 0 0 0 0.91 0.29 134 P 4 -3 -3 -3 -2 -2 -2 -1 -3 -3 -3 -2 -2 -4 6 0 -1 -4 -3 -2 54 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 0 0 0 0 1.08 0.29 135 S 0 1 -1 -1 -2 -1 -1 2 -2 -3 -3 -1 -2 -3 -2 4 2 -4 -3 -3 0 10 0 0 0 0 0 21 0 0 0 0 0 0 0 58 11 0 0 0 0.55 0.29 136 N -2 -1 7 0 -4 -1 -1 -1 0 -4 -4 -1 -3 1 -3 0 -1 -4 -2 -4 0 0 89 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0 0 1.05 0.29 137 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 1 -2 -4 -3 -2 -2 -4 -3 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.26 0.29 138 F -3 -4 -4 -5 -3 -3 -4 -4 -3 -2 -1 -4 -1 6 -5 -3 -3 10 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 46 0 0 0 54 0 0 1.80 0.29 139 T 0 -2 0 1 -2 -1 -1 -2 -2 -3 -3 -1 -2 -3 -2 4 4 -4 -3 -2 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 57 34 0 0 0 0.62 0.29 140 T -1 -1 -1 1 -2 3 1 -3 -2 1 -2 -1 -1 -3 -2 0 4 -3 -3 -1 0 0 0 10 0 20 9 0 0 13 0 0 0 0 0 0 50 0 0 0 0.45 0.29 141 A 0 -3 -4 -4 -2 -3 -3 -4 -4 4 0 -3 0 -2 -3 -2 -1 -4 -2 5 7 0 0 0 0 0 0 0 0 26 0 0 0 0 0 0 0 0 0 67 0.65 0.29 142 Y -3 -2 -3 -4 -3 -2 -3 -4 4 -2 -2 -3 -2 2 -4 -2 -2 1 8 -2 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 90 0 1.35 0.29 143 L 4 -3 -3 -3 -2 -2 -2 -2 -3 -1 3 -2 0 -2 -2 -1 -1 -3 -2 -1 62 0 0 0 0 0 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0.50 0.29 144 G -1 -3 -1 -2 -3 -2 -2 5 -3 -3 -3 -2 -3 -4 -2 1 3 -3 -3 -2 0 0 0 0 0 0 0 55 0 0 0 0 0 0 0 9 36 0 0 0 0.78 0.29 145 S 0 -2 2 -1 -2 -1 -1 -2 -2 -2 -3 -1 -2 -3 -2 3 5 -4 -3 -2 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 38 53 0 0 0 0.64 0.29 146 N -1 -3 3 3 -4 -2 -2 5 -2 -4 -5 -2 -4 -4 -3 -1 -2 -4 -4 -4 0 0 19 18 0 0 0 62 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.29 147 P 0 -2 -2 -2 -2 -2 -2 -2 -3 -2 -3 -2 -2 -4 5 1 4 -4 -3 -2 8 0 0 0 0 0 0 0 0 0 0 0 0 0 38 9 45 0 0 0 0.89 0.29 148 I -2 -4 -4 -4 -2 -4 -4 -5 -4 5 1 -3 0 -1 -4 -3 -1 -4 -2 4 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 0 0 30 0.76 0.29 149 V -2 -1 5 -1 -3 3 -1 -2 -1 1 -2 -1 -1 -3 -3 -1 1 -4 -3 2 0 0 45 0 0 18 0 0 0 10 0 0 0 0 0 0 8 0 0 19 0.45 0.29 150 T -1 -2 -1 -2 -2 -1 -2 -2 -3 -2 -2 -1 -1 -3 -2 1 6 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.95 0.29 K Lambda Standard Ungapped 0.1353 0.3158 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1639 0.3180 PSI Gapped 0.0502 0.2670