Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 V -4 -6 -6 -7 -4 -6 -6 -7 -6 5 3 -6 2 -3 -6 -5 -4 -6 -4 5 0 0 0 0 0 0 0 0 0 33 28 0 4 0 0 0 0 0 0 35 1.23 1.60 2 R -3 7 0 -2 -7 2 -2 -5 -1 -6 -6 3 -5 -6 -5 -1 -3 -6 -5 -6 1 62 4 2 0 8 1 0 1 0 0 17 0 0 0 3 1 0 0 0 1.47 1.74 3 H -3 -1 1 0 -3 0 2 -3 0 1 0 -1 0 -3 -4 0 3 -3 -2 2 2 3 6 5 0 4 14 1 2 6 10 4 2 1 1 5 18 0 2 14 0.26 1.80 4 I -2 1 -2 -3 -4 2 1 -5 -3 3 0 -1 0 0 -5 -2 0 -2 -2 3 3 9 2 1 0 9 8 0 0 18 9 3 2 4 0 2 5 1 1 23 0.39 1.78 5 A -1 -1 -1 -1 -5 -2 1 -4 -3 -1 -2 0 -3 -4 4 0 3 -2 -2 2 5 3 2 4 0 2 9 1 1 3 3 7 1 1 19 7 18 1 1 13 0.39 1.78 6 I -4 -4 -4 -2 -5 -3 -2 -6 -4 5 3 -3 0 0 -4 -4 -1 -6 -3 3 1 1 1 2 0 1 4 0 0 38 23 1 1 3 1 1 4 0 0 16 0.78 1.76 7 P 1 -2 -2 0 -4 1 1 -4 0 -2 -3 1 -2 -3 5 0 -1 -3 0 -1 11 2 2 5 0 7 9 1 2 3 3 8 1 1 30 6 3 0 3 4 0.51 1.77 8 A 5 -4 -2 -3 -2 -3 -4 -1 -4 -4 -5 -3 -3 -3 5 0 -1 -6 -3 -2 42 0 1 1 1 1 0 4 0 1 1 1 0 1 31 7 3 0 1 2 0.99 1.76 9 H -1 2 1 -1 -5 1 2 -1 1 -2 -2 2 -1 -4 3 0 1 -3 -2 -1 6 9 7 3 0 5 11 4 3 3 4 11 2 1 12 7 7 0 1 4 0.22 1.74 10 R -5 8 -4 -5 -7 -2 -3 -6 -3 -6 -5 -1 -5 -4 -4 -4 -3 -6 -3 -6 0 94 0 0 0 1 0 0 0 0 1 1 0 1 1 0 1 0 1 0 2.30 1.76 11 G -1 -2 -3 -5 -6 -3 -3 7 -3 -7 -6 -4 -6 -5 -2 -3 -4 -6 -4 -6 4 2 1 0 0 1 1 85 0 0 1 1 0 0 2 1 1 0 1 0 1.86 1.80 12 L -1 1 3 2 -4 0 2 -3 -1 -1 -1 0 1 -4 -2 1 1 -1 -2 -2 5 7 12 9 0 4 13 1 1 4 6 6 3 1 2 10 10 1 1 3 0.20 1.82 13 I -5 -6 -6 -6 -5 -6 -6 -7 -6 8 0 -6 0 0 -6 -6 -4 -6 -4 1 0 0 0 0 0 0 0 0 0 82 5 0 2 4 0 0 0 0 0 6 1.84 1.80 14 T -4 -3 -4 -5 -3 -4 -4 -6 -2 0 3 -2 -1 3 -6 -3 1 -1 6 1 1 2 1 0 1 1 1 0 1 4 27 3 1 12 0 2 9 1 26 10 0.79 1.91 15 D -1 -5 -2 8 -3 -3 -2 -3 -5 -6 -5 -4 -6 -4 -5 -1 -2 -7 -4 -6 5 0 0 81 1 1 1 2 0 0 1 0 0 1 0 5 3 0 1 0 1.88 1.90 16 R 0 7 -2 -2 0 -1 -2 -4 -2 -4 -5 0 -3 -4 -5 0 -2 -3 -2 -2 9 58 1 2 2 2 2 1 1 1 1 4 1 1 0 8 2 0 1 3 1.12 1.89 17 N -3 -1 7 2 -3 -1 -1 -2 2 -5 -5 -1 -3 -2 -5 -1 -1 -2 -1 -5 2 4 52 12 1 2 3 2 4 1 1 4 1 2 0 4 3 1 2 1 1.09 1.96 18 G -3 -4 0 -2 -6 -3 -3 7 -2 -5 -4 -3 -1 -3 -6 -3 -4 -2 -3 -6 1 1 4 2 0 1 1 78 1 1 2 1 2 1 0 1 1 1 1 0 1.63 1.96 19 E -1 3 2 -1 -6 1 2 -4 -1 0 -2 2 -1 -2 -5 -1 0 -6 -1 1 4 14 10 3 0 6 12 1 2 5 3 13 1 2 0 4 6 0 2 12 0.30 1.96 20 P 0 -2 -3 -4 -2 -2 -1 -3 -2 1 2 -1 0 -1 4 -2 -2 -1 -2 2 7 2 1 1 1 2 5 2 1 9 16 5 2 3 23 3 3 1 1 14 0.40 1.96 21 L -3 -5 -6 -6 0 -5 -6 -6 -6 2 6 -5 2 0 -6 -5 -3 1 -1 0 2 0 0 0 2 0 0 0 0 11 69 0 4 3 0 0 2 2 2 4 1.22 1.88 22 A 6 -3 -5 -5 -1 -2 -3 -2 -2 -2 -3 -3 -1 -2 -3 -1 0 -5 -2 1 60 1 0 0 1 1 1 2 1 1 2 1 2 1 1 3 6 0 1 11 0.93 2.02 23 V -2 -1 0 0 1 1 1 0 0 0 -2 -2 0 -1 -3 0 3 1 1 0 3 4 4 5 3 6 8 8 2 6 4 2 3 3 2 6 18 2 5 8 0.15 2.10 24 S -2 -2 5 2 0 -1 -1 -2 0 -3 -3 -2 -1 -5 -2 3 1 -6 -1 -3 3 2 29 10 2 2 4 2 2 2 2 2 2 0 2 21 8 0 2 2 0.59 2.07 25 T -1 3 0 -1 -1 0 0 1 0 0 -2 0 0 -1 -2 -1 1 1 0 1 5 13 4 3 2 5 7 9 2 6 4 6 3 3 2 5 8 2 3 10 0.10 2.08 26 P -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 27 V 1 -1 -1 -1 1 -1 -2 -2 0 0 -1 -1 1 -1 -1 0 1 2 0 3 12 4 3 3 3 3 3 4 3 4 5 3 3 3 3 8 9 3 3 19 0.14 2.13 28 T -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 29 T -1 1 1 1 0 0 0 -1 0 -2 -3 -1 0 -1 -2 1 3 2 1 -1 4 6 7 6 2 4 5 4 3 3 3 3 2 2 2 9 17 2 5 4 0.13 2.20 30 L -1 0 0 0 2 -4 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.06 2.12 31 W -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 -5 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 5 5 5 0.07 2.12 32 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 33 N -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 34 P -2 0 -1 -1 1 -1 -2 -2 1 -2 -2 -1 1 -1 6 -2 -1 2 0 -2 4 4 3 3 3 3 3 3 3 3 5 4 3 3 35 3 3 3 3 3 0.54 2.19 35 K -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 36 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 37 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 38 M -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 39 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 40 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 41 K -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 42 E -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 43 R -1 1 0 0 0 1 0 -2 0 -1 0 1 0 -1 -1 -1 1 2 0 0 6 6 4 6 2 6 6 3 3 4 8 9 3 3 3 5 9 2 3 6 0.01 2.26 44 W -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 45 P -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 46 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 47 L -2 -1 -1 -1 2 -1 -1 -2 1 1 2 -1 1 1 -1 -2 -1 2 1 0 4 3 3 3 4 3 4 3 3 7 21 4 4 5 3 3 4 2 5 5 0.10 2.26 48 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 49 A 1 0 0 1 -1 0 1 -1 0 -1 -2 2 -1 -2 0 0 -1 1 -1 -2 12 5 5 6 2 5 9 5 2 4 3 11 2 2 5 6 5 2 2 3 0.05 2.26 50 A 0 -1 -1 -1 1 -1 0 -2 0 2 1 -1 1 0 -1 -1 -1 2 0 0 9 4 4 4 3 3 5 3 3 12 13 4 3 3 3 4 4 3 3 6 0.03 2.24 51 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 52 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 53 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 54 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 55 T 0 0 -1 0 1 0 1 -2 0 0 0 0 0 0 1 -1 -1 2 1 0 7 5 3 5 2 4 8 3 3 5 10 6 3 4 6 5 4 3 5 6 -0.01 2.23 56 K -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 57 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 58 F -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 59 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 60 D -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 61 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 62 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 63 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 64 Q -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.02 2.12 65 N -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 66 A 0 1 -1 -1 0 -1 -1 0 1 -1 -2 1 0 -1 0 2 0 3 0 -2 7 8 3 3 2 3 4 7 3 3 4 7 3 3 5 14 5 4 4 3 0.06 2.25 67 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 68 R -1 0 0 0 -5 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.12 69 E -1 1 0 1 0 1 2 -1 1 -2 -2 0 0 -1 0 0 -1 2 0 -1 4 7 5 7 2 6 12 4 3 3 3 6 3 3 4 7 4 3 4 4 0.05 2.25 70 F -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 71 I -1 -1 -1 -2 1 -1 -1 0 0 2 -1 -1 1 0 -1 -1 -1 2 0 3 5 4 3 3 2 3 3 6 3 12 7 3 3 3 3 4 4 3 3 18 0.09 2.26 72 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 73 L -2 -1 -1 -1 0 -1 -1 -2 0 2 2 -1 1 0 -1 -2 -2 2 1 1 4 3 3 3 2 3 4 4 3 11 21 4 3 5 3 3 3 3 4 8 0.12 2.24 74 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 75 R -2 3 0 0 0 0 -1 -2 1 -1 -2 1 1 -1 -1 0 1 2 1 -1 3 17 4 5 2 4 4 3 3 4 4 8 3 3 4 6 7 3 4 4 0.11 2.25 76 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 77 L -1 -1 -1 -2 0 -1 -2 -2 0 2 1 -1 1 -1 -1 -2 0 2 0 2 5 4 3 3 2 3 3 3 2 10 14 4 3 3 3 4 5 2 3 16 0.09 2.24 78 T -1 -1 0 1 1 0 -1 -2 0 -1 -1 -1 1 -1 0 1 2 2 0 0 4 4 5 8 2 4 4 3 2 4 7 4 3 3 4 10 12 3 3 6 0.03 2.24 79 P -2 -1 -1 0 0 1 0 -2 0 -1 -1 0 1 -1 4 -1 0 2 1 -2 4 4 3 6 2 5 7 3 2 4 6 5 3 2 17 6 5 3 5 3 0.15 2.23 80 E 0 0 0 3 -6 1 3 -2 0 -2 -3 0 -1 -2 -1 0 -1 1 -1 -2 8 4 4 14 0 6 21 3 2 3 3 6 2 2 3 6 4 2 3 3 0.25 2.23 81 Q -2 -1 -1 0 0 3 2 -2 0 0 -1 0 1 -1 -1 -2 1 2 0 0 4 3 3 6 2 12 12 3 3 5 5 6 3 3 3 3 7 3 3 7 0.10 2.24 82 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 83 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 84 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 85 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 86 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 87 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 88 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 89 K -1 0 1 0 1 0 0 0 1 0 -1 1 2 0 0 -1 -1 3 0 -1 4 6 8 5 3 4 5 8 4 6 6 7 5 4 4 4 4 3 4 4 0.02 2.24 90 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 91 P -2 -1 0 0 0 0 1 -2 0 -2 -2 1 0 -1 4 -1 -1 2 0 -2 4 3 5 6 2 4 9 4 3 3 3 8 3 3 19 6 3 2 3 3 0.19 2.24 92 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 93 V -2 -2 -2 -3 0 -2 -3 -3 -1 4 0 -3 0 1 -2 -3 -2 2 -1 4 3 2 2 2 2 2 2 2 2 20 8 2 2 6 2 2 2 2 2 27 0.41 2.24 94 Y -1 -1 0 -1 0 -1 0 0 3 0 -2 -1 0 1 -2 0 0 3 3 -1 5 4 4 4 2 3 5 6 6 5 5 3 3 5 3 6 7 3 11 4 0.08 2.24 95 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 96 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 97 E -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 98 E -1 0 0 0 -5 1 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.10 2.01 99 F -1 -1 1 -1 -1 1 0 -3 -1 -1 -1 0 0 0 2 1 2 3 2 -2 4 3 5 3 1 7 6 2 2 3 6 5 2 4 9 12 11 4 8 3 0.17 2.02 100 R 0 3 -1 -2 0 0 -1 -2 0 1 -1 2 2 -1 -2 -1 -1 1 -1 1 6 13 3 3 2 5 5 3 2 7 7 12 5 3 2 5 3 2 2 10 0.14 1.97 101 R -2 7 -1 -1 -6 0 -1 -5 1 -2 -2 0 1 -5 -1 -2 -1 2 -4 -2 3 51 3 3 0 3 3 0 3 3 3 3 3 0 3 3 3 3 0 3 0.91 1.88 102 F -2 1 -1 0 1 -1 -1 -2 1 -1 2 0 1 1 -5 -1 0 2 3 -1 3 8 3 5 3 3 5 3 3 3 20 5 3 6 0 4 5 3 10 5 0.18 1.83 103 Y -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 104 P -2 -2 -1 -1 -6 -1 -2 -3 -1 -2 -2 -2 -1 -2 7 -1 -2 -6 -2 -2 3 2 3 3 0 3 3 2 2 3 4 2 2 2 56 4 3 0 2 3 1.23 2.08 105 A -1 -1 3 0 0 2 0 -2 1 -2 -1 -1 0 1 -2 -1 -1 1 4 -3 6 4 12 5 2 10 5 4 4 2 5 4 2 5 2 4 4 2 15 2 0.26 2.16 106 G -1 -1 0 0 1 0 -1 4 1 -2 -3 0 0 -1 0 0 -1 2 -1 -2 4 4 5 6 3 4 4 30 3 3 3 5 3 3 4 7 3 2 3 3 0.29 2.12 107 E -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 108 V 0 -2 -1 0 1 -1 0 -2 1 0 2 -2 1 0 0 0 -1 2 1 1 6 3 3 6 3 3 6 3 3 6 19 3 3 4 5 6 4 2 4 9 0.08 2.03 109 V 3 -5 0 -2 1 -1 -2 -1 0 -1 1 -2 2 3 -5 -1 0 2 0 -1 22 0 4 3 3 3 3 6 3 4 12 3 4 10 0 4 7 3 3 4 0.23 2.04 110 A 4 -1 -2 -3 1 -2 -2 0 -1 -3 -3 -1 0 -2 -2 3 -1 0 -1 -2 34 3 2 2 2 2 3 8 1 1 2 3 2 2 2 23 4 1 2 2 0.48 2.07 111 H -1 0 0 0 3 1 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.07 2.01 112 A -1 0 1 -4 3 1 0 -1 -4 0 -1 -4 2 1 0 0 0 4 2 0 6 6 6 0 6 6 6 6 0 6 6 0 6 6 6 6 6 6 6 6 0.17 1.78 113 V -1 -1 -4 0 -4 0 0 -1 -4 1 1 -1 1 0 0 0 0 -4 2 1 5 3 0 5 0 5 6 6 0 7 15 4 4 3 5 6 6 0 8 11 0.12 1.58 114 G -4 1 1 1 -5 1 0 0 3 -4 -1 1 -4 1 -4 0 0 5 2 -4 1 7 7 7 0 7 7 7 7 0 7 7 0 7 0 7 7 7 7 0 0.29 1.45 115 F -2 -1 -1 -2 1 -1 -2 -2 1 -1 -1 -2 2 3 -6 -2 -2 2 7 -2 3 3 3 3 3 3 3 3 3 3 5 3 5 11 0 3 3 3 35 3 0.74 2.05 116 T 0 -1 -1 -2 1 -1 -2 -2 0 1 -1 -2 1 -1 -1 -2 2 -5 0 4 9 3 3 3 3 3 3 3 3 7 4 3 4 3 3 3 14 0 3 24 0.25 2.02 117 D -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 118 V -1 -1 2 1 -5 -1 -1 1 0 1 -2 1 0 -1 0 0 0 2 0 -1 4 4 9 7 0 3 5 10 3 7 5 8 3 3 4 8 6 3 3 4 0.09 2.09 119 D -1 0 0 0 -5 1 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.10 2.01 120 D -2 -1 3 2 -5 0 0 0 2 -1 -1 0 1 -1 -1 0 0 2 1 -1 3 3 12 11 0 4 6 8 4 3 5 5 3 3 3 8 5 3 5 4 0.15 2.03 121 R -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 122 G 0 1 1 0 -5 1 0 0 -4 0 -1 0 2 -4 1 0 0 4 -4 0 6 6 6 6 0 6 6 6 0 6 6 6 6 0 6 6 6 6 0 6 0.15 1.67 123 R -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 124 E 0 -2 -1 0 0 -1 1 -1 -1 -1 -2 -2 1 -1 -2 3 1 1 2 0 9 2 3 5 2 2 9 4 2 4 4 2 4 3 2 21 7 2 7 7 0.18 1.93 125 G -2 -6 -1 -2 -6 -2 -5 7 0 -2 -3 -5 0 -1 -6 -2 -2 2 0 -6 2 0 3 2 0 2 0 68 2 2 2 0 2 3 0 2 2 2 3 0 1.31 1.96 126 I -1 -6 -6 -7 1 -5 -6 -6 -6 4 4 -6 2 0 -6 -2 -2 -5 -1 2 4 0 0 0 3 0 0 0 0 26 38 0 5 3 0 3 3 0 3 14 0.88 1.72 127 E -4 -3 -3 0 -7 1 7 -5 1 -6 -3 0 1 -6 -4 -2 -4 -6 -5 -5 0 0 0 4 0 4 76 0 3 0 3 4 4 0 0 3 0 0 0 0 1.52 1.53 128 L 1 1 0 -3 -2 1 0 0 -1 -3 1 3 0 -2 -5 -1 -3 1 3 -3 13 8 4 1 1 6 5 7 1 1 13 19 2 2 0 5 1 2 9 2 0.27 1.67 129 A 3 0 -3 -3 -2 2 -2 -3 -1 -2 -2 -1 0 0 -5 2 0 0 4 -1 21 5 1 1 1 10 2 2 1 3 3 4 2 4 0 16 5 1 16 4 0.39 1.67 130 F -3 -3 -4 -4 -2 -1 -3 -4 0 -2 1 -4 3 5 -6 -4 -4 2 7 -1 1 1 1 1 1 3 2 1 1 1 11 1 6 20 0 1 1 2 40 3 1.12 1.71 131 D -3 -1 4 5 -6 1 4 -3 -2 -5 -5 -1 -5 -4 -5 -2 -3 -7 -3 -4 1 3 21 30 0 5 28 1 1 1 1 3 0 1 0 1 1 0 1 2 0.99 1.70 132 E -1 0 1 4 -3 0 2 -1 0 -4 -4 3 -3 -4 -2 2 -1 -6 -3 -4 5 5 6 19 1 4 14 4 2 1 1 17 1 1 2 14 3 0 1 1 0.45 1.74 133 W -2 0 -3 0 -1 2 1 -5 -1 0 0 -1 -1 0 -2 -2 0 2 4 1 3 5 1 5 1 9 11 1 1 6 10 3 1 4 2 2 6 3 16 10 0.28 1.77 134 L -4 -5 -6 -7 -1 -5 -6 -3 -6 0 6 -6 1 -1 -6 -5 -4 -5 -4 -1 0 0 0 0 1 0 0 3 0 4 84 0 2 1 0 0 0 0 0 3 1.48 1.66 135 A -1 0 0 0 3 1 0 -1 2 0 -1 0 2 1 0 -1 0 -5 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0 5 5 0.07 2.01 136 G -1 -1 -1 -1 1 -1 0 5 0 -2 -3 -2 -5 -1 -1 -1 -2 2 -1 -2 4 4 3 3 3 3 5 42 3 3 3 3 0 3 4 5 3 3 3 3 0.53 2.01 137 V -1 0 0 0 2 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 138 P -1 -1 1 1 1 -1 0 -1 2 -1 -2 1 0 -1 2 -1 0 2 1 0 6 4 7 9 2 3 5 4 4 3 4 7 3 3 12 5 6 3 4 6 0.12 2.14 139 G -2 -2 -1 -2 0 0 -1 6 0 -2 -3 -1 0 -2 -2 -1 -1 1 -2 -3 3 2 2 2 2 4 4 50 2 2 2 4 3 2 2 4 4 2 2 2 0.73 2.14 140 K -1 1 -1 -2 -1 0 0 -1 0 -1 -2 2 0 0 0 1 1 1 2 0 5 6 3 2 1 3 7 5 2 3 4 13 2 4 4 10 8 2 7 7 0.12 2.14 141 R -2 3 -2 -2 -2 2 1 -4 -1 1 0 2 0 -2 -3 -1 0 0 -1 1 3 15 2 2 1 9 11 1 1 8 10 11 2 2 1 4 5 1 2 9 0.24 2.15 142 Q -2 2 -1 -2 -2 2 1 -3 -1 2 0 1 0 -1 -3 0 1 0 0 0 3 11 3 2 1 9 8 2 1 10 8 8 2 2 2 7 8 1 4 7 0.15 2.16 143 V -2 -2 -2 -3 -2 -2 -2 -2 -2 2 0 -2 1 1 -4 -1 -1 0 4 4 3 2 2 1 1 2 2 4 1 10 10 3 3 6 1 4 4 1 12 26 0.37 2.15 144 L -1 0 -2 -1 -3 2 4 -4 -1 2 0 0 0 -1 -2 -1 0 -1 1 -1 4 5 1 3 1 9 23 1 2 10 9 4 2 3 2 4 5 1 6 5 0.26 2.15 145 K -2 3 -3 -4 -2 0 -2 -4 -2 0 -1 2 0 -2 -5 -1 2 -6 -1 4 3 16 1 1 1 4 2 1 1 5 5 12 2 1 0 4 12 0 3 25 0.42 2.13 146 D -2 -2 4 7 -6 -3 -2 -1 -2 -2 -4 -2 -2 -4 -4 0 0 -6 -3 -4 3 2 16 50 0 1 1 5 1 2 1 2 1 1 1 6 5 0 1 1 1.07 2.10 147 R 4 1 1 -3 -3 -2 -1 1 -2 -2 -2 0 -2 -3 0 1 -2 -2 -3 0 31 9 6 2 1 2 3 10 1 3 3 6 1 1 4 9 2 1 1 6 0.33 2.11 148 R -1 3 2 2 -3 1 -1 -1 1 -3 -1 2 -1 -1 -4 1 -1 1 1 -2 5 13 9 10 1 6 3 6 4 1 7 10 2 3 1 9 4 2 4 3 0.20 2.11 149 G -2 -2 1 -2 -6 -2 -3 7 -2 -5 -4 -2 -3 -4 -4 -2 -3 -2 -4 -5 3 3 6 2 0 2 1 68 1 1 2 2 1 1 1 3 1 1 1 1 1.32 2.11 150 R -2 5 3 -2 -3 2 0 -3 0 -2 -4 2 -2 -3 -4 -1 -1 -2 0 -1 4 27 15 2 0 7 5 2 3 2 2 11 1 1 1 4 5 1 4 4 0.50 2.13 151 V -1 0 -2 -2 -5 0 1 -4 -2 3 0 0 0 -1 2 -3 -1 2 -2 3 5 4 2 2 0 4 9 1 1 14 10 5 2 3 11 2 4 3 1 17 0.26 2.10 152 I -3 -4 -4 -4 -5 -2 -2 -4 -3 5 2 -2 3 -1 -1 -3 -2 -2 -1 3 2 1 1 1 0 2 2 1 1 28 21 3 6 2 3 2 3 1 2 19 0.61 2.07 153 K -1 3 0 0 -5 0 2 0 -2 -4 -2 1 -3 -3 4 0 -1 0 -2 -4 4 13 4 5 0 4 12 7 1 1 4 9 1 1 21 6 3 1 1 1 0.39 2.05 154 D -2 -2 2 3 -5 0 1 1 -1 -2 -3 -1 -1 -3 -2 0 2 -3 -2 0 2 3 11 16 0 3 10 12 2 3 3 4 1 1 2 6 13 0 1 7 0.29 2.07 155 V 0 -3 -2 -2 -3 -3 -1 0 -3 2 2 -2 0 -1 -2 0 1 -1 1 2 6 1 2 3 1 1 5 7 1 11 20 2 2 2 2 9 7 1 4 13 0.19 2.04 156 Q -1 0 0 1 -5 2 3 1 -1 -2 -2 2 -1 -3 -2 1 -1 -2 -2 -3 5 6 5 8 0 8 18 9 1 2 5 10 1 1 2 11 3 1 1 2 0.23 2.02 157 V 0 0 0 1 -3 1 2 -2 -1 0 -1 0 -1 -1 -2 0 1 -2 1 1 7 4 4 6 0 6 11 3 1 6 7 6 1 3 2 7 8 1 5 11 0.09 1.99 158 T -2 1 -1 1 -5 -1 2 -3 -2 2 -1 -1 -1 -2 -3 0 3 -1 2 1 2 7 3 7 0 3 12 2 1 10 5 3 1 2 2 6 15 1 6 11 0.23 2.03 159 K -2 2 -2 -2 -4 2 1 -3 0 0 -3 4 -2 -2 -2 -1 1 -4 0 1 3 10 2 2 0 9 9 2 2 6 2 23 1 2 2 3 9 0 3 9 0.34 1.90 160 N 0 -2 0 2 -6 0 3 -3 -2 -3 -3 1 -3 -5 5 -1 -2 -6 -3 -3 10 2 4 10 0 4 20 2 1 1 3 7 1 1 26 4 3 0 1 2 0.61 2.08 161 A 4 -3 -4 -3 -4 -3 -3 0 -4 -4 -4 -2 -3 -4 6 0 -2 -4 -4 -1 28 2 1 1 0 1 2 7 0 1 1 2 1 1 40 6 2 0 1 4 1.03 2.10 162 K -3 1 -2 -2 -4 3 2 -5 -1 1 -2 3 -2 -4 -4 -2 1 -4 -3 3 1 6 1 2 0 11 11 1 1 9 3 18 1 0 1 2 8 0 1 23 0.47 2.11 163 P 1 -1 3 4 -4 0 -2 -3 -1 -5 -5 0 -3 -5 5 0 -3 -4 -4 -4 10 4 15 22 0 4 2 1 2 0 1 4 1 0 24 6 1 0 1 1 0.74 2.10 164 G -2 -5 -3 -4 -6 -4 -5 7 -6 -6 -6 -5 -5 -7 -4 -3 -5 -4 -5 -6 2 0 0 0 0 0 1 92 0 0 0 0 0 0 1 1 0 0 0 0 2.20 2.12 165 K -1 0 4 1 -3 2 1 -2 2 -5 -3 3 -1 -3 -4 1 -2 -3 1 -4 6 5 17 8 1 9 7 3 4 1 3 18 2 1 0 9 2 0 5 1 0.41 2.14 166 T -3 -4 5 6 -5 -3 -2 -3 -1 -6 -7 -2 -5 -7 -2 1 1 -7 -5 -5 1 1 22 48 0 1 1 1 1 0 0 2 0 0 2 9 9 0 0 0 1.25 2.13 167 L -4 -6 -7 -7 -5 -5 -7 -7 -7 5 4 -6 0 -3 -6 -5 -4 -6 -3 4 0 0 0 0 0 0 0 0 0 26 39 0 1 1 0 0 0 0 1 31 1.27 2.10 168 A -2 1 -3 -4 -3 3 -1 -5 3 -1 -4 1 -1 -3 -5 -3 2 -2 5 3 2 7 1 0 1 12 4 0 6 3 1 8 2 1 0 1 12 0 17 21 0.56 2.10 169 L -5 -6 -7 -7 -5 -6 -7 -7 -7 -2 7 -6 1 -3 -7 -6 -5 -5 -5 -3 0 0 0 0 0 0 0 0 0 0 98 0 2 0 0 0 0 0 0 0 2.01 2.03 K Lambda Standard Ungapped 0.1378 0.3190 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1042 0.3129 PSI Gapped 0.0319 0.2670