>QUERY >UniRef90_K8AG65 >UniRef90_B1ER62 >UniRef90_Q04866 >UniRef90_UPI00046867F8 >UniRef90_C4ULS4 >UniRef90_G9Z9S9 >UniRef90_C4S2J1 >UniRef90_UPI000346DBCF >UniRef90_Q05032 >UniRef90_S3IGT2 >UniRef90_A0A023VDQ5 >UniRef90_V5CA46 >UniRef90_L0M2T5 >UniRef90_B7LUF8 >UniRef90_UPI00037B1702 >UniRef90_W1F2X7 >UniRef90_UPI000466DACF >UniRef90_A4WC76 >UniRef90_UPI0004663C22 >UniRef90_G9Y0Z2 >UniRef90_G2SC24 >UniRef90_E8XML6 >UniRef90_G8LD69 >UniRef90_K8CQM3 >UniRef90_V5CVG0 >UniRef90_UPI0003782147 >UniRef90_E9CP44 >UniRef90_K6WLI4 >UniRef90_G2S9S3 >UniRef90_M0QEN8 >UniRef90_D1P2Z4 >UniRef90_B7LLL3 >UniRef90_D5CJ87 >UniRef90_C7BQJ9 >UniRef90_UPI00046F6F38 >UniRef90_E6WHE5 >UniRef90_UPI0003800188 >UniRef90_E1SK72 >UniRef90_D0Z975 >UniRef90_W0HLS5 >UniRef90_U7R782 >UniRef90_R9VIU8 >UniRef90_L0M8Z0 >UniRef90_V3VDI3 >UniRef90_UPI00047904C8 >UniRef90_G9Z3A0 >UniRef90_UPI00046A0F0D >UniRef90_D6DXG5 >UniRef90_J0ME53 >UniRef90_W0AR61 >UniRef90_J7SL74 >UniRef90_V3PYW7 >UniRef90_R9NIR1 >UniRef90_UPI0003797706 >UniRef90_G9AQ03 >UniRef90_D4HUJ1 >UniRef90_A0A023V9V0 >UniRef90_W1J850 >UniRef90_A0A014M9C6 >UniRef90_V1TH48 >UniRef90_S3IMI2 >UniRef90_B2VG62 >UniRef90_UPI00036B047C >UniRef90_C1J8U6 >UniRef90_J1GDV9 >UniRef90_W6J9P4 >UniRef90_B4F1V8 >UniRef90_K8DS27 >UniRef90_D4E8P1 >UniRef90_J2IXC1 >UniRef90_V5AU88 >UniRef90_I0DV09 >UniRef90_E0SKQ6 >UniRef90_N0C3Q6 >UniRef90_H3REH6 >UniRef90_D2BYS1 >UniRef90_G2BS24 >UniRef90_D3V0T0 >UniRef90_UPI0004650BC1 >UniRef90_G0D037 >UniRef90_D3VL58 >UniRef90_V3I641 >UniRef90_W8G8X2 >UniRef90_E5YCS0 >UniRef90_W1IT83 >UniRef90_C4SX57 >UniRef90_UPI000470A64B >UniRef90_D2TWT2 >UniRef90_V0KF36 >UniRef90_C6CGI1 >UniRef90_B6VNS2 >UniRef90_J3DDA8 >UniRef90_C4UHK4 >UniRef90_C4UEK2 >UniRef90_B4F1Q0 >UniRef90_G9Y1M4 >UniRef90_H5Q983 >UniRef90_Q7N0P7 >UniRef90_U9YDG2 >UniRef90_A0A018RCN2 >UniRef90_D4F3J1 >UniRef90_C4U0G8 >UniRef90_U9DP30 >UniRef90_I2NF21 >UniRef90_UPI0003682E63 >UniRef90_I6SUE7 >UniRef90_C5BCN1 >UniRef90_V5SU48 >UniRef90_D4C4B9 >UniRef90_K3K7W9 >UniRef90_W1IXJ9 >UniRef90_D0JFR4 >UniRef90_I3BGV0 >UniRef90_R9WN05 >UniRef90_I3DHW5 >UniRef90_K8XCJ8 >UniRef90_UPI00031E6456 >UniRef90_I0DR95 >UniRef90_M7KYL2 >UniRef90_C4SZ47 >UniRef90_K8W5R3 >UniRef90_UPI0002ECA75E >UniRef90_UPI0002DB9487 >UniRef90_M9QXJ0 >UniRef90_UPI0002D5DC41 >UniRef90_UPI00029A866F >UniRef90_J0UJB6 >UniRef90_A5KZS4 >UniRef90_UPI00037F5E39 >UniRef90_K0GEV9 >UniRef90_D1P4F6 >UniRef90_X6ZLU7 >UniRef90_F3VUC7 >UniRef90_S2EV48 >UniRef90_D4C4E0 >UniRef90_J1EMX6 >UniRef90_UPI00037AE5AF >UniRef90_W7NLG3 >UniRef90_R9WM58 >UniRef90_G2L6W5 >UniRef90_K8WQW4 >UniRef90_D6NLY6 >UniRef90_B0BR52 >UniRef90_J2MHL3 >UniRef90_F9T0J3 >UniRef90_W0Q5B5 >UniRef90_B7VHQ6 >UniRef90_F9SJ67 >UniRef90_K1IPS8 >UniRef90_J7UK60 >UniRef90_W0BVG8 >UniRef90_UPI000472B1D3 >UniRef90_K8X9B9 >UniRef90_M4XRE4 >UniRef90_C4L7N8 >UniRef90_UPI0002D939D5 >UniRef90_A6V2R5 >UniRef90_A0A010SRV1 >UniRef90_U9CH62 >UniRef90_UPI00047D6EB1 >UniRef90_Q8KHM2 >UniRef90_A1JMR4 >UniRef90_UPI00035D6D67 >UniRef90_J3A6K2 >UniRef90_C9P0E2 >UniRef90_D6NLW0 >UniRef90_D0IMS9 >UniRef90_K9NHD9 >UniRef90_V2LNF1 >UniRef90_V9ZXS7 >UniRef90_V9WTC5 >UniRef90_UPI0002EFB2B4 >UniRef90_I6CP78 >UniRef90_G3XCY2 >UniRef90_UPI000361284B >UniRef90_W0FTW7 >UniRef90_S6BF76 >UniRef90_Q65UU8 >UniRef90_V5FA94 >UniRef90_D0Z7Z5 >UniRef90_U5VB82 >UniRef90_U4E657 >UniRef90_A0A023S933 >UniRef90_A6ADU0 >UniRef90_C5S1B1 >UniRef90_UPI000382CA97 >UniRef90_A0A018ZL94 >UniRef90_UPI000363ED9A >UniRef90_V3A7K8 >UniRef90_UPI0002197CB7 >UniRef90_J8V7R1 >UniRef90_F4HEY6 >UniRef90_A0A024E7N2 >UniRef90_F4DHZ1 >UniRef90_Q1ID96 >UniRef90_C9Q3M2 >UniRef90_W9TAL4 >UniRef90_F5PKF2 >UniRef90_S2KQS0 >UniRef90_UPI0004670C44 >UniRef90_Q2C7A7 >UniRef90_J3GU52 >UniRef90_UPI0002E5377B >UniRef90_P44063 >UniRef90_C4S6D6 >UniRef90_UPI0003955B5E >UniRef90_UPI00046E509F >UniRef90_UPI00030BACFE >UniRef90_UPI00036C86D2 >UniRef90_Q9JRS3 >UniRef90_E3BJ74 >UniRef90_UPI0002556BD3 >UniRef90_UPI0003132912 >UniRef90_D4FB19 >UniRef90_V8GAD7 >UniRef90_W8UFU1 >UniRef90_X4XRL8 >UniRef90_D0GV84 >UniRef90_UPI00037E641B >UniRef90_E4RDS5 >UniRef90_G8Q1S0 >UniRef90_K8D6E2 >UniRef90_UPI0003785B80 >UniRef90_D4C4B4 >UniRef90_L1LSG8 >UniRef90_UPI0003F4BED8 >UniRef90_Q842P3 >UniRef90_B3FN90 >UniRef90_J2UZW4 >UniRef90_UPI00036A35C9 >UniRef90_R1GU00 >UniRef90_UPI000306DCE6 >UniRef90_F9RKG4 >UniRef90_A0A024EZL3 >UniRef90_J2YDI6 >UniRef90_A0A059L6A2 >UniRef90_W0LLP5 >UniRef90_J3F1G3 >UniRef90_UPI0004747E15 >UniRef90_UPI00046F9CEF >UniRef90_M9S5H8 >UniRef90_UPI0002EF71F4 >UniRef90_H1RTE9 >UniRef90_W0A132 >UniRef90_F6CZ43 >UniRef90_J3E1V3 >UniRef90_Q9XBT8 >UniRef90_W8PGQ8 >UniRef90_X0NXL4 >UniRef90_UPI00036B8944 >UniRef90_W7NHD9 >UniRef90_F9THH1 >UniRef90_B0KTY6 >UniRef90_J3GAH5 >UniRef90_UPI0003A13F84 >UniRef90_UPI0003B2F588 >UniRef90_UPI0002F72303 >UniRef90_Q1ZRK1 >UniRef90_UPI00036002C0 >UniRef90_R8ARZ4 >UniRef90_UPI0004650A92 >UniRef90_UPI00042A4745 >UniRef90_F2P9Z7 >UniRef90_UPI00036C79FD >UniRef90_C4S7J8 >UniRef90_UPI00026C7D04 >UniRef90_UPI0003736BEE >UniRef90_J7U1U5 >UniRef90_UPI000374959B >UniRef90_UPI0002FE0424 >UniRef90_A1SRR6 >UniRef90_M4U5Q5 >UniRef90_Q1Z8B9 >UniRef90_T2HBE8 >UniRef90_UPI0003B58AAE >UniRef90_V6UZM0 >UniRef90_UPI0002D2C920 >UniRef90_K8C390 >UniRef90_T0QTB1 >UniRef90_UPI000380CF22 >UniRef90_Q1N5G1 >UniRef90_M5DTE4 >UniRef90_UPI00036D853D >UniRef90_Q2BJF5 >UniRef90_W9A4D1 >UniRef90_A6VMI6 >UniRef90_UPI0003642BF7 >UniRef90_F4GVY5 >UniRef90_C4K3Z7 >UniRef90_F4HBI6 >UniRef90_A5UI14 >UniRef90_Q1PGY3 >UniRef90_UPI00046EADBA >UniRef90_UPI0002FF205A >UniRef90_X8MDY9 >UniRef90_Q1QWX5 >UniRef90_Q31F07 >UniRef90_G9ETS7 >UniRef90_UPI00037DC6F2 >UniRef90_A0A034T008 >UniRef90_UPI00030C1CC7 >UniRef90_UPI0002D5BD76 >UniRef90_I6ZZV3 >UniRef90_D0YWK9 >UniRef90_A4BIX4 >UniRef90_C0AX79 >UniRef90_S6ATQ8 >UniRef90_L0GKN7 >UniRef90_T0P9Z5 > > > >lupas_21 >lupas_14 >lupas_28 >jnet >conf >sol25 >sol5 >sol0 >jhmm >jpssm * iteration 1 KKKKKQKQEKEKEKKE KQKEKEKKKEEEKKKKKKK K KEKKKKEKK KKK K KK K QKKKKKQKKK K KKK K QKKKKKE KRKKKQ K KKQ Q K KKK QQQK K K Q Q KK K Q K K Q Q KQ Q Q EQ Q EQ Q K QQ Q Q K K Q Q EQE Q K R K K K E Q E K K K KE K K RK Q 9 WWWWWWWWWWWWWWWW WWWWWWWWWWWWWWWWWWWWW WWWWWWWWW WWW WW WW W WWWWWWWWWW W WWW W WWWWWWW WWWWWW W WWW WW W WWW WWWWWWW WWWWW WWWWW WWW W YWW WWWWW W WWWW W WW WWW W W WW WWW WWWWW W W W W W W W WWW WW WWWW W W WWW W WW W W WW W W WWWW WW WWW WWW W W W W WW WW Y WW W 9 TTTTSSTSSTSTSTTS TTTSTSTTTSSSTSSTTSTSSSSTSTTGSTTTTTNT ST NS T TTSTSTTTTS T TTT T TTTTTSS TITATT S TTT TS T VTS TTTTSSS SSSTS TSSTT TSS T IST STSSS T STTS T TT SSS T S RT TST TTSTR S T T S T T T SSS TS TTSS T N SSS T TT L T TT T T TTVS IS STT VIS V T T T TS TS V TT S 3 E SSSSTASATSASASSA SSSASSSSSTAASATSSASTSTAAASSAASSSSSSS TS ST S SSSSASSSSST SASSS S SSSSSAA SSSSSS S SSSSSS S SSS SSSSSSA SSSSSASSASSS SSS S SASASSSSA SASSSSASAS SSASAAA AAS SAASSA SSASS T SASAAASAASAS SAS SS SVAS A SAA A SSS AA AS N AA ASS S AS ASAA SS SSS AASAAAT AS S SS SS S S SS A E1B E TTTTTTTTTITTTTTT NTSTTTKEVTVTKTTASTKTTTAITIQITNEKESTKTTQ QIT Q KSKQIEEQQTT TTTTE T TDTVDNT SKTTQT S TYTRTS Y EAT KKTEKTK TNDTTKVSSTEK QKK K KKQKKKESS EKTKKTRKRK YKKKKKK HKN TKKKKEKKQKKS K KKQKKSSKKDRK KTN KK KKTK K VRE K SKQ KN KT S QKKKKD K SK KTKNK KE KTVQKKSKKKK KS T KS ST K D YS S E5 EE AAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAA A SAAAAAAAAAA AAAAA A AAATAAA AASAAA A AAAVAA A AAA SSAAAAA AAAAAVAAAAAI AAA S AATGAAAAA AGAAAAVYAA AAYAAAV ALA ATVAASVAAAAA A AIALAVALLAVS AAA AA AAAA L VVV A AAA VA AA AA ALALAS A AA AAGAA AA AAAAAGGEVGIA SA A AA AA A A AA A E8B BEE IIIIVIIIIIIIITII IIIIIIVIVVIIVIIVITVIIIIITVMVIIIVIVIVITT III I IVVEMVVEEIV TVIAV A IVAVVVI STIVAI S IEIAIK E IVV VVIIKVT IKKVKSYKKEIT LTK V ITEYKTEKV VYVTVKIYST IEYKTTF IYK RYSTRTIKLKEA V EYLFTSVYFTYI EIK EK QYIT F FFT F KILYFV YI IF IFTFVI K IE VVKMY VE RRELQKQIFKIV TV ETVIE VI I Y EI V E8 EE IVIITTITTVTITIIT VIITITIVITTTITTVITITVTTTTIITTVIIVITITTV VVT V VVIVTVVIITT VTIVI V IIVIVTT VIIIII I ILIVIIVLVIVI VVIIIVV VIVIVIVIIVIL IIVI VTVVVVIVIVVVLVIVFIVIVVVVVIVVVV III IVIVTILVVVVVV V I VMVTVVVIIVLL ITI II V IVTVV I IVL V IIIIVL IIVIV VVVIII VITV IIVTL II IIVIIVVILVLIV IL VILIA IV V L LV V E7B EE TTTTDDSDDTDTDTTD NTTDTDTTSDDDTADTSDTDTDADDSTDDTTTTTDTDDTDTDD TDTTTTESSTTDD TDTVS V VIVAVDD ITVVTT V TVILVTLILSTV IIVIMIS ITAVAISTSVIL ASSI ILSSIVTITAALVVIIDALSLILSISTSSI YQA LVQQIVSQASSIV L T ILSISVTQMTQI GDT II E MSDTE M SLA I AAGSVL LTVSD TETMTT TVMI TTIDD TT YVTSKIITALMTS YA ISLTV TD S L IT A E4 EE QMQQRKQRRQRQKRKK MQTKQRPLAKRRPSLPQLQRMRSKLAPKKPQPLPYPRRLRPLR PRVPPPRIRPPLK LKQKT K PPQPALR QYPPKP K QPKPAKPPPPPQ PAAPAPQ PEEAEPAKEAQP PLQK APQQAPQANKEPAPPAAQPPPVPVEPKQQP KPA PAAAAEKPLEQAA P D APEPQPPPPRPE TKE AQ P VPRQP P SPK PP VAEPPPPAPPPK VPQPAP TAPA TTARR TK PEAEPAEEAKPTI TS ATPYP PR Q P PV A E1B E PPPPPPPPPPPPPPPP PPPPPPAPPPPPAPPAPPAPPPPPPPAPPAPAPAPAPPPPAPP PPPAPAPPPAAPP PPPPA P PPPPPPP PPAPPP P PAPPPAPAPPPP PPPPPPP PAAPAPPAAPPP PPPV PPPPPPPPNAPPPPPPPPPPPPPTPPAPPP PPS PPPPPPPPPPPPP P P PPPPPPAPPGPP PPA PP P PPPPP P PPP PP PPPPPPPPPPAP PPPPAA PPPP PNPPP GA PPTPPPPAPPPPP PP PPPIA AP P P AV P 7B DDDDTTDTTDTDTDDT DDDTDTEDDTTTETTEDTETDTGTTDETTESEDETETTATEIT ETSEEETETEETT SSDTE G GQGGQTT QSGGMQ Q DQSSRQSQSDER KKRTQSQ EQQRQTRQQKTP TEQQ KSEQRTQKEQKRSTTKKQSTSKSSKTQQQT KSQ SRRKKQYTQSQKR S K TTSTQTESTQTS QNTQ RQ S KRTLS T ETY TS QQTTTRRTQATY QTETQE QSTN KKQLY QE YQESSQQNAQARE RS TLRDS EQ E K QD K 6 VAVAVVAVVAVVVAVV SASVAVQSAVVVQIVAATQVSVVMTAPVVSAQTPVQVVAVPTV AVASSKVTAKKVA AVVLT L DGLNTVV LSENLL L AADLSPLALIPA VVTSVSL LPPSPQVPPLSL IILP ALILVQTLLLQLLQSLLVLALLWDIFPLLQ QQS LLIIVVLQLVLVL L P TQFQLLSQQYMF FVVP ID R AIVLQ Q VLQL QL VILQQILDLLDF VQLQYD LHYA VAITS YL PVLLLVLYTLKVT NE GTVDN AL I A ASAA AP 3 GGGANNANNGNGNAAN GAGNANTGGNNNTNNVANSNGNNNSGSNNTGTGINVNNGNVNN ANGVSINRGPINA GAGEP E EEEEQNN EGEEDG E ARESTQSRSGVV AATEHEQ KQRTQSEQQNES NGQQ ASGQTKQTQQESTKETESSNNTSGSEQQQN RNQ SSASANNNYSQTV S E VNSNQSVNNKNN QTNQ TQ D VANQN N SGNN NS QQQNKAAGGGSN SNSNQI YNKV ARNTS QQ INRKQNTNSNNAP QS VYANG IS G S REGG GE 4 QQQQMNQNMQMQSQQM QQQLQNQQQNAMQTNQQHQMQMSVHQQMMQQQQQNQMMQAQNM QAQQQQNQQQQNM QMQQQ E QEEQENM EQQQEQ E QESDDNDENQQG NNDEDDD EDNEDQQNDNEA DQDD NDQGDDDEDDDDDDDEEDSDEESKDNDNGD DEN DNEQDDQDNQDDD N D SDQDGQQEGDDQ SNND ED E QQMDD G NQGQ DD DEQGDQDDQSQE DDQGNQ NDDS EDDQE ND DDDQEDDDDDGDQ DD DQDQS QQ Q E EKGG GD 5 IIIVLLILLLLILIIL IIVLVLWIILLLWLLWILWLILLQLIWLLWVWIWLWMLVLWLL LLVWLWLLLWWLL VLIFL Y ILFLLLL IILMML I VLIVLIVLVLWF LLLLFII VLLLMIILLLIV VLIM LIIIIIILRIMILIILIYVIILIMLIIIII TII VTLVMFLILVILI V L LIVIIVWIITII IVLI LF I LFLII I FLIL II FFIIILIILILL FIVITW LIIL VIVLI TR IFMVVVVLIVIVL LL MILLI WL I I LILL LM 0BB H AAAASGAGGAGAGAGG AGSGASNAVARGNGGQAGNGAGGGGAQNGSASSQGNSGASQGG ISASITGIASAGS ASAQI Q QTQDTGG QAQQKA Q ASQADAAAAAQQ GGGNSNA NASGAASASGSA ASAV GAAASEAGVSTAAETGGSAASGAQGAATTA LAE ATGTGAAAAAAGQ A L NAAATASAAAAS DAGA GAGA GEGAA A NSAA EA TSGAAGAAAEQT SAVAAQ ASAN ARAGA AI EAPNEAASAAAVI DI GDAQE QA A Q SASS ST H0 H GSGTSGSGGSGTGTAS NTSGTSPNNSGGPGSETSPDNSGGSGEGGQNSNEGPGNNGDSD EGNEEESENQEST NTGPE P ASPKSAG PNVRQD P TSVGPAGAGNEP DDTEETG AATKAEAASNEG NNGA DGESENAEMAPGLNEESEGNGDGPENAASN EQA GESGSINQEASSH G P NDPQSEEQENDS SSGA DASQ SDGGQ E SNDN NG QAAEDDGADGPE QQTENE ELNN IITSE NM AVEESATSDVETE QE AAGPA DV E D AESS SP H0 H YYYYYYYFFYYYYYYY YYYYYYLYYYYFLYYLYYLYYYYYYYLFFLYLYLYLFYYFLYF LFYLLLYLYLLYF YFYLL L LLLILYY LYLLLY L YMLFIYFMFYLL YYLFYLY FYYLYLYYYYFF LYYY YFYYYFYYYYMYQFLYYYFLFYFLYLYYYY LLY FLYFLYYLYLYYI F M YFLLYLLLLIFY IFYY YYLL YYYYL L FYLY LF YYLLLYYFYFLL YLFLIL YILY FFLYL LY LYLFLLLLLLLFL LI YLYFL LY Y I MLYY YM H6BB HH NNTTYYNYYNYNYHSY TSTYNFRNTFYYRYYEAYRFNYYFYSEYYHNRSEYHYYNYEYY RYNNHQYQNQQYF NFNKQ K IDKTDYY KTDTRP K THDNRQNNNPEQ RRRSQSQ KQQRQNRQQRAN NPQQ RNYQRNQREQLNRNGRYQNNNRNERNQQQN DNQ NRRNRRPNEQQRN N R RNQNQNNNNRNF NQYQ FQQN LRYQN N NPNP NN QQQNNRNNPNEN QNLNRN ENNR SSYFN RQ NRSQEYYRNYNSQ RR GNNEL EY Y N NEDD DS H7B HH NNDNSSTSSNSNSNNS NNNSGSQNSSSSQSSRNSQVNASSSNRSSQAQNKSQSGASNST RSVKRKSRTSRSD AENNR N SANNESS NAKNAT D NKKIAQISQEKK SSAAEAQ ARQAQYRQQKAI YTQL SLNQKYQRQQKLAYTRENQYLRLSKYQQQY RYQ QSQTSQQYKLQKN L K RYLYQKKFYSYL AQSQ KNRY ERSKF Y NEYR YL SKLYYRLRTVRI KFQYSK KYYR QESAS SQ YQQLLAQNYSLQR EK NSQYD KD N R SNNN T NK H8 HH AAVAQQAQQAQAQAAQ SAAQAQASAQQQAQQTAQTQSQQQQAAQQAAAATQMQQAQTQQ AQAEAAQVATAQQ TQAAQ A NQESQQQ LLNSTA I AEAVEQAEGATV EEERQQV QQQEEGAQQERG GAVQ EGAAEGQEQQVGAGQEFQGGGEGSEGQAAG LGQ GVAGEQVGQAAEP G Q EGAGAGEGGQGV SQQQ EVQG AAQVG G KAGG GA QQKGGNGSAGSG MGQGQK QGGE TNQQG QQ GQQNSQQDGQGAV NI AGAKL TQ A L EFRR E RQ H8B HH MMMLQQLQQMQLRILQ MLMQLALMMEQELQQFLQLQMQQQQMLQQLLLMLQMQQLQLQQ MQLLMLSLQLLQQ LQMLL L LLLLLQQ LLLLLV L LLLRYVRLRVFL YYYLVLV LVVYVRMVVYLR RVVV YRMVYRVYVVARLRLYTVRRRYRLYRVVVR RRV RQYRYVWRVVVYK R A YRVRVLLRRVRM LVQV YFFRLEFQVR R RVR RR VVIRRYRYVRLR VRVRIL VRRY VIVQR VV TVMIVSVVRVRVL IQ FLHLQ FR M N LFLL L LA H8B HH NNNNQQNQQDQNQNEQ NNNQNQQGSQQQQQQTNQQQSQQQQSRQQQNQSRQQQQAQTQQ VQNSVQQQNQQQQ AQNQQ T TSNTAQQ TNATNA T NNDGATSNTNTQ AAASTSKSDKTARTATKAST TSKT ASNKNTKNKNTSTASSQTTTKNASAEKKKT TGK TRADAKTGTDKAS T G AADGKKSGGTTK SNQR ANDGSRAQQG G QDT IG KTDGTGADA SS NGKGTS SGGA KDGQT TK TKNDNNSSTGIKQ KQ AVQKQ TQ N A NDDD S ET H8 HH VIAVFFIFFVFVFTVF VVTFIFVIIFFFVFFVIFVFVFFFFIVFFVVVVVFVFFIFVFF EFAVEVFVIVVFW VWVVV D VVVVIFF VVVVDV K VDIKRVRQKLVV SSRAVVRRVQVRQSRVQRAR RLRV SELRLKQRKVAEAKVRQVSPEREVRKQRRL AEK RIRKNSMGVKRRI K A RLKGRAVEKNFS LQFQ RVEGLRRFRG K FLRV DS QVLTRLEKVRLS GGQKND QESR RNAFS NQ FSAKQKVPSAKRV LI QILLR KL L T QIFF L FA H7 HH ILILLLLLLLLLLLLL LVLLLLLLVLLLLLLLLLLLILLLLLLLLLLLLLMLLLVLLLL LLLLLLLLILLLL LLILL L LLLLLLL LILLLI L LIIDILDLENLL IIILLLYILFLIFEVLFILS ESYL I VYIDFIFYLALDLILLDGSI LISFYYE LGF ETIGIFNNLIYIN E L INISYSLGSLGL LYLF IFVDVYVLID S LLEI QK YLISEVATIELA FDYGLL FAEI LLILA LF IFLLLVILQIDLL YI IS FL LL V L LFFF V FL H1B H YYYYNRYRRFRYR YS YYYRYRDYSRRRDRRDYRDNYTRRRSDRRGYDNDRDNNYKDRN TNYGVDRDSDDRRYYRYSDYY DGNDGRR SYDDDDYE YQISIVSASFDN LLIGVDQLDQVIQSTVQTDE SLQV LNMQISQLQQG GSDLRVSSDLNNLSQQQN DTQ TDLDLQDSVQQLN V G LSQAQLGTTYAS NQRQ LQYSDYSRVS T IRSL SS QVRTSL SDNNT QSQSYD QTTL EYLRS YQ KQNKISLFTVSED GY AS DI RD M G ALLL D MG 1 GGGGNNPNNGNGN GN MGPNGNVGNNNSVNNVGNVNANNNNNVNNVPVALNVNNPNMNN LNPVLVNVPVVNSLSSGLVLV IILIINN LSIIVPMV GVDGGSGLGPLI DDGMSVPRVPSGPGGSPNFG ENPS DGNPGQPRPELKVQVRRSGG RGIGAPPPE IGP GNNGNPGGSNPGP G L GDAEPNVGDSES VPNP GDLGVLGNSG E EEES KG PSGEEQGLPGIG PGPGII PGEG LVNGG IP PPVNNLNIGNELV LS KSSIS VN N I LNNN V NL 6 QTQGLLTLLALTLDGL QNTLNLDQDLDLDLLDSLDLQLLLLDDLLNQDQDLDLLQLDLL DLQDDKLDQKKLLRDLQDDRL KDEKDLL QDNTDSRL GDVLDKLLLTDE IIDDKKLDPVQDVLNKVSNL LSLD ILDL LVVVDSL LKVTNLLLVLDQLVLLL QLI LSQLIDDLEGLQK L Q SLILL DLLVLV DILV DPLDEILEL L KQLQ LL VQDLLQLLSLNL ALLLDE ILLS DNALL NA LITSAVDVLDLDD HE LLQSN LS D G LFNN D NG 7 ATANDDTDDNDNDSGD SANDADVNNDFDVADAADADNDADDEVEDIDVSVDVIDDDIDD ADDFAVDADPSDDSDDAPTSN VFSLFDD PDLLTNSN NADPSEPDQTIS KKGVAIFAVFENFDQEFDIA AAFE KP FSTFDFGGA TIDLAQKGETL NFFFS GAF GSPAKNNSKAF E E G DPSPFSFADIAD AFDF SGSSTSGDAS D GTTM PR FSSEESPKNDLE FIFEDP FAVD NSDDE DF KFAISDAAEAAVA GT PKALE DS DN DN T G 8 AAAASSSQAAIAQSAA AAAQAVKARAWSKQSGALKAASQTLRSSAGKKPNTKAAKMNLV ATKDAPTAKSSSASKAAKQSL DNSGSSK SRGGGSSQ ASAPELPIASKG DDDDLDDFDDLDNPTLN DP PDDL DA DEPDPSTFETPDPQLPVVPTNEPDDDP LPN PDLPELAVLPDED P FS PSLDPDPTDPS NSQD ETLTGDAKLY P YWPL QP DLQPPVVPSADQ DPDPSN DVP LLLLQ SS ADVPPLLAPLPLA IA DPINP LA AQ IE G F 8 PPTPPLPPPPPPPIPP PPPPPPIPFKLPILIIPPIPPPLPPYVPKLMIPILIPPPPVPR PPLIPIPITLVLPPPSPVIPV VVLIILP VPIIV PP PPDFFDFIFPII FFFLDLVLLIDFVYIDLFLF YTVH FF VFYIIIVPFPYLVKTFFFIFIFFIVVY KLV FVDFFVPIDPVFI F PIFYLIVAILYVFI IYPI FVPYVFDPDL Y LAFL FF VIRYYLFF YIY ILLYSL IIIF IVFPY SI ITSPFFFFFFYII PS IIYFF IL YF ID V P 7B KNRKSKNGTESKGTKS SRLSSPTTDSQSTSNDSSSTSTSSSDKSSDPTSDQTSTSTSTN KVANNDSDSDSTTYSSKTDYT SGTTDNS TTTTN YS KAYTSSTAKNDS SSSSSSYQSYDSYSDSYKGT TYYS SS YKTYDYLSKDTSDSQKTSDSTDTYYYT SSY KDTSTNVSSSYDD K SYDSESYDNSSSTD HDGY DLDSNDPSST S DDSS TT YSDSSQTK TTS YTYSKD YTTD ESEPT KY TYDDEEESTESND SS TSHDS DN SY AY N S 5 VVVIVSIIVMAAILVA VLVILIRVIISVRAVRMIRVVVAIIIKVQRIRLRTRVILVRIQ IIIRVAVAIKPTAVIAVEAVE AEKPESV SISPA VV IQLVALVQVGRQ QQASLAQQAQLTQLTLQQSV VDQL QAVQEIQPQVGVVITPQAVIVPVAVVQQQI NVQ VVAPSPIVLAQAI V GLVVQVQARTIVIR QRIQ AIAVGVQVLV I KVP VV QPFIVQVV VSP QVQIIQ QVVV RQPVP IQ VQLVKPPPSPVEA AT VSAQM RA V VL QL G G H2B HH STQSDDNSMTMTASSM VVSASSPVTSDMPSMSQPPMTMPASASASNSAAGDPSMSISPS DDTDDNTAPVDDAMISSAKMS NKEAKDM SNNNSKMT SSLSGGSTQNTK DDGQVQETQEVGDKHVDSAS KMET DNSENKDNSSKETKQNSNQDKNNDNDDEEK NKD QSNNKSDKTSEGN Q KKNKPGEEDKRNKK DESD SSGKSSVMIK Q MAKT KN ENAKKSEKKRYD EKEQNK EKKN EADQE NA YDPSGSKNRAKRA QT DTSKQ GS S NS TSQQ S QK H8 HH DDDEYYDDEDDEDDDD DDDDDDDDGDYEDSGSDEEDDDSDDGEDAEDDEGYQDDGDDDD AEDNAEYSAEDYYDNPDSYDS YESYEYD SDYYSDES EDSQADQDDEEL KKKRDQDDRDDGDSADDERD DSDD KGGDEDDADDDDDDRADSDEDADDGDDDDE AED DAGDDQDDDADAK D DSSDADDKSDHNDY DQDD MKADSD DDD Y DDDD DE DSDQYDKDDSDQ DEDYSD DDDS SLTDQ KN NDASATIKKTDTT DD TEDNG GA G DS DDDE S ED H9 HH LVLVYYVYYVYLYVVYYVIIYVYVVIYYYVYYVIYVYIYYYYIVVYVLVIVYLYYLYVYY VVLAVIYLLVVYYLIYLLLLL LLLLLYYYLLLLVIIV VYTVLLVYVLVL VVLILIIYVLVLLVLLLLIV VLIL VVYIIVLLILLV VILYLVVILVLLVLIIV LVL VLLVVIIVLIILF V LLLVIVIIAVVIVI FIYL TLAVVNIYIV V ALVD VI VLLVVYIVIIIV LVIVIV LVVL LDLYV II IIALLLLIVLVIL L LI VVALI AV Y VL YYLL V LL H9BB HH QQQQKKQKKQKQKQQFKQQQQQKFQQIKKFYKFQKFKQKYQYQFYYFQFQFKFKKQQFKYQYYQFYFKEQFYKRKQYQYEKY LLYMLKKRYQLIYSSN QYFYSFYYYTFY SSSYFFFLFF SFYSFFVYY YPFF SYDFRYFSFFYY YFSYYYYYSYLRYFFFY YYF YMFYVFTYFYFAL Y YQSYYYFYFYYFYF FFKF AFKYYKAKFY Y ESYT YF PLKYYYYYSYIY FYFYRF FYYS FEFRF SF FFFQYFFFFFYFE M YF SYALS FC FS YYFF Y FY H9B HH EQAAQQVQHAQTQNYQQNTQESQNEEQQQNQQNNQDSYNQTKQTARNHNQNSDKSNNNKQAQQRDQNQNENNQAGNREQSED SSKSSTQEHHSSQNAT ARKSDQSKSTNE EEDNQNKKTQENKDSQESNR DTRQ ESYKNGKAQQQASGNAHRSKDASMKKKQKS NEQ SNSADAGGAKKNI E QSNDNSQQASDEDG ETQQ NKDDQQNQKD D ATDS SS QQTDEKSSNASA SEQDEN AESN NKKSA DQ SANQGRSIDKDEN N SG KNQSS ND NL KQQQ Q PL H9 HH TRSNRRRRRGRNRQDRRRSQRRRQRRRRRLDRLRHLRRRSRQRQEALQLRLRLHRQRLRRNNEQLALRMLLLRRAQETRLAR TLRSLRRRNQTNKDLE NQQVSRVTVRLR KASENARMARVSRVLRRDEV VKRY KIDREVRRRREVWVTSNLVVVSVDSVRRRV DAD VRDVNQNVQSRGN V EESVSSHTLIVRVS ERRR NRKVKKQRRI V AKVN VE QQQLVKIVDIEY LTRVSA QLIS RRNRY AR SQVEDNLDIIVRM Q QQ SMRLS LE D TQ TKQN K NE H9 HH LVLFKQVLKFQVQVFQMFVFKVQFFVKQQFNLFAQFKFKHKHVFFHFLFYFMFQKLKFRQFFFLFFFKFLFFLQQLRLFFKF FFFFFMMQFVFFFVEY FLNFLFFLFVFF VILFFFFLFFLLFFLFFLFF FVFF VFPFLFFLFFFFLFFLLFFFFLFFLFFFFF FVF FALFLFVYFFFLI F FALFFYFFFYFLFF FFLF LFLYFFLMFH F GVFN FF LYIFFNFFVFFF YHFFLF FYFL FLFTF LF AFFLFFFFFFFFF N FF LFVFL FV P YQ LLII F LF H9BB HH IVIISEIESIVVKIFSVFFFEIEIFITESIKEIIEISFTKKRIIIQLFVFVEITSFSIDTILVFILLELFLLEKIFRIVLII KVVVIEVHLFKIIFLF ITFIYITRLFIL FFYIIILMIVFYILFIVFIT LFLV FVVISIVFVVIKSTIFVIILIFLRFLVIIT LRI VFIKFVFLIILFF T IVFAIVITILALTI RIEV FIWVILFVLL T IFLG LT FIFALVTEFSRV ILVALI IALF VLIEV LV LIGYVIVIVILLL F II YLFIF IY V TK RVEPV I TI H9B HH GGSSGGGGGGGGGNNGGNESGGNKGGGGGKENKGGKGNGEGKGKGKKVKGKNKGGGGKDGSKGSKKKNKNKKNGQGKGEKDE QREQRGGGNNQQNAHK SADRGDRERNKG NNGISDQKDNKGNRSNNSTR HNQD NRKQESDNDDLRGSDNIDRHRNRKDRDQQR LDD RRTQNRNRQSQAN R QRSRSRQRKKRNRD RNGD GDDRNKSGQQ R TNRS KS QDNRRARQARKR QQRRNK QRQS QRNGR ND HRTKSNRNRNRQK A LN RQQQN KQ K EE EKTKK N EQ H9 HH RRRRNDRDNRNRDRRNNRRRDRDKRREVNKGDKRDKNRNGDGRKNGKRKRKDKNNRNKSNRDDRKDKDKRKKDDDRGRNKDN NDNNDNNDNRNNNNRN RSNRQTNRNRKD DDQQAQEKQARQTNAATKQN NLET DNKELYANLTENRYENNENNNNNYKNATEN EKT NTKRNSTNAAEKN N EDKNANTRKANENE YLDA QARENNRNEA N DLNR NN SASNNNNRNNYR QAANDK AHSK TTANR DL KSRSNASEQSNAK N DR NNRLQ KE K NK RKRRT N RE H9 HH FFYFAAYAAFSFAFFSSFFLVFAFFFSTSFSPFFAFAFASADFFRDFFFFFAFANFAFVVFFAFFFFAFFFFPDLFDFYFLY FFYFFASGFFFFYFAL FMYFFFLLLYFY FFFYYYFNYFFFFLFFFFYL LFFF FLAFFFFFFFFLFFYFIFLLLFLYFLFFFL FFF LFFLFFFLFFFFF L FFFLFLFLFFFFLV YFAF FFFLYSFSFL L DFLS FL FFFFFLLSFLYL FLFLYF FLLF FFFAF YF FFLFFFFYFFVFF F FY FLHFF FF A FY LSGGD Y SF H9BB HH SSSSHKNKKSKSRNSKKNSNKNRQNNGRKQAKQNRQHNHAHVNNKTSSQNQKQSHSRQKGSDRGQDNQDNNAKKHGNSNDHN DDNNDKKKNSDNNVIV SRFFKNQLQLQD KKKRNRNPRNVKNQRNNNRE QLNN KQFNSQNNNNNLIQRNKNQQMNLSNQNNNM KFN QLKIKNIQNNNNL Q NRNFNNNAQRFIQV SNKN NNNNNTNKNQ Q KLQV KQ INVFFNREVLSI QQNQIK NYRN NVNRF IN FNSINNNNFNQND D NK FRLNV QL F KS LKDDI N EN H9 HH SSTSEAAASSATASTAAAAAAAASSSAAASRASSASNSNQARSSARSASSSASKKAQSAKSSQASSSASGSSAARAKSSSRS SSSSSAAASASSSSVA SDKRRSSSAASS TTRSSSANSSNRSANSAESA SAAS TSNARASRSSSSRASRSSSSARASQSSASA SRS ARESRAASSSALD A ASQSSSASSNNTSS SAAS LSSSSSEAAS A GAAS NS MSARENSASSST SSTGTS SSAQ ANSAQ TS NAQVSSSSKSAAS RQSN SSSSN SL N NS SNSSQ S QS H9 HH AATADDADDADSDAADDLAADSDQAADDDQADASDQDLDADVAADAASQAADQDDSDADDAEDSAQADTTEADDASAARAAR QQREQDDDRSQERREE AAKEKAESDNAR AAQKSKNDKTTESEQTSAKD DNTT AELNYESRSNYDTEKLESDEELEKQDSTTE YTS DKTDETMESKTLA D YALEMENDAAEEEV RTDN LTDERKKDTE ETKNEA TE ANADESEARDQD KENEES SERL TYSDE ES QTGAFTAEESEST LNNSNQASNN AQ L KA STTTK R AY H9 HH FFFFAAMAAFAFAFLAAIFLAIASIFAAA DAIFA AIADADFIADII IIA AALAIAAFYAII VALMILAAIMDFFIIF IVDIAAA LDD MLS FLLIFNLLEIIF FLFFNFFEVNFFNAWNNLVE DVFS FEFLV NANNELF VLESESEYYDLNNFF DAN FTQEFAALNLFSN E EFM NFGEIFIF D FEAN SLFD ELAFL SLRIDF YK FQFIYENLIENE SAD FF NFSM NFVGI FN IADFNIDFVLSFL FFEFDSIA I IL F EY LFFFD FE H9B HH SSSSAASAASASAIFAASSSASVLSSVAASAAVSASASAAVATVIAVSSSVASMANAVEASLASVAVAVTVVAVVSASKAVK N L KVAVVN VSSR SSMYLNPATEVK NKLKNKIFNNALNLANNYNN KDLN NTLTLSNVNNNPSSNSKNSITKSMSANLLS NFN NSSSFNNPNVLEV T NLYSNPN VLYN N NSAN ESSVVIRALP LVADSNKVLS ENNYYENNSNVA NVN NL NPNYNNNNQAVNN YNTNNNAIYNLVV SSNLNDKSVS VS M KA TIAAK V AN H9 HH AAAALLALLALALAALLAAALALLAALTLLALAALLLALALAAGLAAALAALLLLALRLRAAFAELLLASLALLVAVAANAA ILSLRLMLLSLLLAKK AAALELSQSAAAATLEALKEKNLLSLKYKLALT NAEL TQLLSLLLLLLSALNNKLLRRKNLKELATL ILK ALLAALASKLESV R RASLKSLLEALASK NKLLLSTVLLAYMAS RALALTLLARLSKLLLKQSAKLKLKAKSAL KSLSLAAKLATAK LLAAKKTLAKRSA LASREALLL ASAL ES QFNAA L EL H9B HH LLLLLLLLLLLLLLLLLLLRLLLILLLLLLLLLLLLLLLLLLLLLLMLLLLLFLLLLLLLLKLLLRLLQLLGLLLLLLLVLL RRLRLLLLRLRRRLNL LLLLQYLKLYLLLYLQMYLFKLYYQYLLRYFLL LDLY YLYQYRYFYYFLRRILLYRRQLLMNQYLLR FLR LFSLQYQLYMLLL L LLLRRLYKLLPFLY YLLYYLLQYRILLLL QQLYYFYLLRLNRLLLQLL KYQLLLKLFS YLLLLLYKLAFFQ LYVLLLFSLKRAQ F KFYQRKL LWYY VF QDFFL R FF H9B HH ASASVDADDADADTGDDSASDSDSASDDDELDSADEDSDLDLSSDLSSESSDEDNSDSEDSSDSSESDRSSNDDSSLALASL ERIEIDDDEAEEEAMI SAIYSSEAYISVIASSLSSNQASASAYSSARAD YIKE AYSKDQAKTVASDQDSDYRAAASSKYAQQR KYI YQSYSSISSRRDD Y RYDQNAEQSYSDRL FADAADAAAENSDKS DRRISIERYDKKQNYYARY ASRLDYQRDS SSYDGNNVDRSDD QSSMINLNYQDLR SKPDKNTEN SDDS RIIGANND E NA H9B HH EEEEEEEEEEEEEEEEEEGLEQEEDEKEEEDEEQEEDEDDEDEDKDEREEEEEEEGEEKEEDEGKEEEIMGLEVESDEAQEA QEEQEEETESQQEFKE EEEREDEFRTEAEDNEDEEKSEKRSKEEEEEKE EVKE AADQEDELEEEEAEQNDDREEEEKEEAKKE QAFKKEERKELEQEKER E DAEEFEEDKAENRK DQEAAEE QEKEEKE EIKEEAEKEQKNFSEDWEHEESQKQSQQNE LESEQENFDQNDS KEGNENADAFFEI ENENGTRKR EDWD EKEFIEEL E EE H9 HH TSAVLLSLMTITLANLMEAQMAMKETLLLYELKALYLELELETKLEKSYQKMYLLALKLLAYLSNYKLKSKKLLKSTTKRKK YYQYKLLLYSYYYMSK VQKAWWRTLQKKRKLWKWQELKWWLWRTWWLLS NKEW KLSMAFWSWWVARFRELWSTSGEEEKWQQF YQWSRLQRWWSEWLDTL S WQRFLKWFNQRWAS SRLWWMR FYLTLEE RKMRFVWMKRMKLLNRLAGTSNATLDQSWY WSERKWKLLASWW SWSRKWYLALFLK RYLELQFYL KRVS KNKTKETW Y EV H8 HH LLLLIVLVVLTLILLIILLLVLIMLLIIIMLIMLIMILILILLMILMLMLMIMIILIMIILVILMLIIMLIIIIMLLLMFMS LLIIVIIILLLILPVI LAIFLFVLFEMIINVVLFVMLIFFIFFDFLVGD FDLF NLYMIFFNFFVELFLNIYFFLKMKLFFMMF IFFIFMALFYGLFALRS F AFEFIQFFMFFAFI LIVFFTE LLAAILF FMVESAFVLLAREAFFIFFLEVLMLFLFAV FQLEGLLEILAAL IYFLMMLLFERLM FLLDIALLI MLEY EFKLNAAA L AV H6B HH DQDDDNDNNDDANDDDNDENNDNKQNGNNTINKENKNDGINVSKNVKQKAQNVASAATNGDKAHKAKNTQKTNNKLIDDKKD VVVLGDNNIAIIVEDV DFISKKGKNKKNEADKDQNMDDDEKKGYNEKDF YKFA AMVEANQEENKNDNVTEKSSDDEVISQFLN LNEDTEKIQQMYEDLEQ S KNNDQKEDKNSKFD KKNAQKS VEYNLA SVNKQNEESGENTDSSNNSTDKYTYNKFKH KKSEEKEKNYDKE LQGADNDKNKDDT ERDIQNAVK KIDV FAAKFFFE V FK H2 HH NNNNNNNNNNNNNNNNNNNNNNDANNANNSNNANNNNNNNANNANNNNSNANNDNNNANNNNDNSNANSRNNNDANNNNMANNNKNNPNNDNSNNNKDN NSNENRSNEAASNNKNNRSNVKRRNRKYRRNKN KSYR NNNQKNKNRRNLFNNSKLKKNE NNRKAEN ENKDDNKNNKDNNTNNN K LGNKEYRRSSRKNM IANKKNT SSKVNNN RSGPSERGKSGFSGRKAKGFENGESRVNRR NAKNVKFNDQNRR YKFEAKDIGNGIS YNRNDFSNS ASNN NIFNNEEK S EN 3 QQQQIIQIIQIQIQLIIQQQIQIVQQIIISQIVQIDIQIQIDQVIQDLNQVINIILIVIIQKILVSVINMNNIIVLDQIQVHNTTKSNIIITLTSTPND QLQDDIVSKTVIISNDKITQIIVIDITKIINNE RNQIIISENVVITIIVLLISFNLQTDQIAIDIQQY QMINQEISIIIQIIKIL V VMIQERIIIMEIQD KSIIIIP KTNKIQL ENINLNIINQILIIVDAKILQNRGKVNDIK IQLILILSIHNIV NIQSVIHKSSQNN LTNQQEITI VDIE DINSIVMI T MH 6 EQEKQQTVQQQEQEEQQDDEVLQDPDQKQPIEDEQTQSLIQIDDQINETQDTVQIEQDQQKAQEDENQDKTDEQDDIESSDSANDNDDQQQEDDDDLTN KSDLPTDQISDSSETPNSDDSQSSPTLQSEEDI LTDSSTVENIY SSKTAQDIIISIIEIQNTV INY DLTAIDWFVSSFSSDAS L SLTLSQQYDLLDVM PFVTSAD LDLQQDL LDSSVPQNLDDDESLLELVPEDMIWLEISI WPLTINEVTMVSS QSKIANDMFIEDD FDEDWDAQSS DITE SEQQTLLI D LD 7 EEEEFFIFFEFKFEKFFEIEFVFNEIFFVFVYEMFQFKFVFQENFQANQIDLQFYELSIYEDLVDYNFNTPKFFSDQEINDEQYFIYEFFFYTYYYDSI ETQRKASLSPDISEIKDGDENDAAKVRQAADYF TPDAGITNDKLTFAAAVAFDITISTLIRNKATQNL LKSSSTIRTAIRVADIV S AKIIIFALDKVAYT TDFAAIE TYSQFNT VNAPVNAAVFASFAITKVTEEQQNSTNYAT AQVIVAGFFSSAA FATSSAISDFEDN SPQNSEFTYV DRFN FHFLYFHV Y FW 7 PPPR TPTTPTPTPPTIPPPIPTTKPTTTVFTNPIVMPTFLFPNTFMPEPNTT TP NT RT PNVITPPVSTMNPFPSDNQGFYPFSTTVFPFFYIKS RPDVKSVDIVNPVAPKPVQPDLSSKSVPFSPNT ILPIGPISPPPAISSQRSSQPVKIIQPPFPVVADP DISKINTII RDVKPTQ I QVTISFSPNVVSLE GATTSKM VYPTTPV IPVVSQSMIAKNQRVIKVVTFNKADVNLSG INVTYINITQNSS K AGSKNVLRTP VGFTKKQTFI NFTS SPIDSPPK Y PS 7 EEEEQLEPAESQPEEAPEEEPEAKEEAPFKLPSEPK E TPIEFSTKEKEAPKQ LQVQQEKQLKKK KLKG PALIEPNAEKKKKKKPPPKIKRKKKS EKKVKMNQTSAKNKDKLASEKSKKKIVETIDAI ASEDKDQPEDSKILPPAPKSDVPSAIDSADSKSAA PTIKSAPEPSPLKAQKL K PAKSAAAKAAKLPT SEAKIKR EKKEPEA KKAAGQASSEAAMVGALSKPDAIKKAEPQH KVSKVVKEAKTQL RA RILVQVDKRK SARTRAKIQT AQAP FKEQKDDK K DK 7 KQKKPHKR KGKRKKGGKKKRKRDSKRR DPASKHDPNPPRPKGHPKDNKSRDPPSPGGPKGPDNKPPAKSSPRGTPKKPSPDRRKYTQGHNDQSNPNS KDNPDEQALISKPPPDDTKQSKVVDESHATPKK PIRANPKLAALQPRVVPGKKAPELPKSKGPPQASL ALANLPPTDPGLELRPP A VVPAKA KSQGNSE VDRLVPSPQSPPGSP AALIDPVQMVPHFQGLNPPLPKVALPTSPK ELQPPESYKVTPA APDPANSKQYRAA NKQQLPNEKP SPEL GGDASPPE S PS 7 LLLLADLDAL LDLL LLLDLDALLDDAAGDKLDAALAGDHLKNYDLALKDVAALAKIALSALDLGAPLAPADKLHLKKKKALLDLAD DLLMLLTDS LKDPLNPTPTKKLKKLVDELAEDDLDADDDKEV VSLEEKPKVKSDDDDDDKIEKIDPLAKDLKLDVAV DANDPDKRIATSSDLDD P DADGALVTKAPDLA AADDDDFDVLLD LA PADFAIDDVLDAKDPTVDDDANLTDADLDL SFTDDDILDLNDD IAGSD ILLLSYA ADYLIDILLD KANK IVFTDKKS L KA 7B TTTTDDTDDSDSDTIDDTKSDSVDKTEDDDEEKTDDDVDDEDTKDDDKDTKDDDDRDKDDTDDKKDTDTNDTDDKNDTDIKKDMSKITDDDIRMMDNKK TGDTTITEDKKNKKKTKKKQSKRKTFGVNAKKP GKQKSKSIDKEGAKKKTGSKKDADDSKEKKDGDVN KGKKGDEDKETSKKQPE D KSEGMSDDKSGETD VTDKKTYATDNEDQG GS KKTKTGRKDKKGDKVPINYKDSKDDKD KTRAVEKKDTMKK TEDDD DYAAQDT KGVDIPTPIM KDQI TSSEKRKL D RT 7 IIIIPKVKAIAIKIIIFIIIAIPKIIKKPKALKIKKPIAAVDINVESAKIKTNSAVSNKAISSKSASEAVNDNANVEINAKDKKEEKDNFAAVKKESSA IMKKEEKSKSKNDDDEDKNKTNKKEKKIKRDDD KPKNADKVKDKRKKRKKRKNDEKRKVERGEKIKGK KKGSKKKKKKAKKIAKK K KKKKDKKKNRKKKK VMKKNKAKKEKKFKK KA PALKSKILKKNKKAKSKKSVKKGKKKA KRKKRKNEKIRKK IKIKK NKGTDKA KGETTKIKKT KAKV H ISKKTI E TA 7 EDEEAKEKLDAEKEETTEEEKEKAEDKKTAAKDDKMAEAAKKDEKAQEAEDKAAAEAEKAETADSIDKSNVTLKEKAEESDDIDTDNTKTKKEDDEGSE EESELNEKTKDDKPPLSSSKKSDDLDAAGDPSK DKKSPPEKKPDDKDNGNEDSPQQADDPEKPDGNKE GDNSDEDANGEDDSKKN N GDKDKDNNDDDKET EEKADKSNDEDKTKG GSAESKASDESSKSDSTNSPPDTLDSTDND DDDKSKDNKTKNN NNLTGSKKEKDTS KDDTEKKKSDK DAKK PEKKKDDL E EQ 7 PTPQR QMKARQ PPRRPPPKPVPQTMTHPKNES PHPHKKKTPKKPPPPEKPKHPKTEKQPKQLPSKPPPPKKTTKPEPEEPNAENAIRKSPENFSLK QDELDRLEQEEDENNDDITEDTPRDREPPRDDQ IDERLNDDANFEDTSENPFNNKLQDGNRNDLKANS EMKLFQNRPR TDQEEK Q EMDSTQAQKMTRQIDNEIEEDDNGFTTRES NPPVPP GAPENKSTSDNPRDNPRN QTQK DALDNESNTPWQK ERKGKQKQPKLNP NT NEDNQGHKDERVD KAMEDNNN F NP 7 SASSGVA NANSVSSNATVTTAPYTAPPNYKPYTVYNANH VAATKYVYAYLYNNDNY NSYNNYYYLYNYYNTSTKSDYYLYYYFDY ATDNYVSKYD SFYPKNPYPMYEYSSKDTSENSRNKNPYNNTDQ DADNYSSKNAPLPSKVPYASAVNPGSA ILGQNNS QPSYPTIPNR PEDDPS P EPSPSSNPYPPPPRKRNPFNLGPPSKLAES PYSG GNNLPNQDNPPNP NARPESSAPPT EAPPPNQIPPPPD PRPSRTAGPSYNY SE NINATQYGKYGNKADFPYYRRK S RV 7 VVLVLLVLTVIVLVLLVVVVNVNVVVNNTATTTVLVTVLSLLVLNTSVLLTVVLTDITLLVTIDVTAVSDQALNLDTVDSTKVRSYGSLINDNRDGDVD VAREISETSGTNRIIISSSGNNSSISD SSISP DNASRIEDDLDANSSPDPGTIKSDGGI NLGSEDD PDSVGTSDLD DYIGDT N PDKDQDEQVDDNDSINDNSSIDDNGDPINT DSDNDADVDTINLVEDVDTDDGSDSTGDDT QADDDVVS DIDA NDADASSDRGAES DQLLNNDDDVNITTFDSGSTTISSSDG SD 4 PPPPNNPNSPSPNPPNNPPP P SPQ SSS APNSLPPDPNQF NSPSPSNSNRSNSNNPANTSSSNSPSST FSNKESSESYYEGYHN HYYDESSE PYYRGPRYRYSIYGGSDPDMYDPPGPR PPGDG RYIPSGRYIGRPAPSGYYRDGFTRRRG NGRPITR GRPSRDYRGETRV ALS R GRARDRIRSRRVRVANT PPGFYREIYNIRYLSNYGTI RKIIFMRRKRKSRNLVIRDRVS IREGNVLEFLEVP QETILEVNAERLS YFFGHSMIQFNASHNYEAKGYFAASQE AK E5B EE LLLLDDIDDLDLDLLDDLLLDLDWLLDDDWDDWLDWNLDDDDLWDDWLWLWDWDDLDWDDLWDLWWWDWLWWDDWLDLSWWTWYYTYYDDDVLYYIFWT LYYYLYYYYYWSYVVLIYIFFIYYLYYYYYVIY WYFYWVYYFSYYIYYVFLYIRPYYWYRYYRWYFFY IYYWYYYYIYFFY FIY Y IYLYMYFYWYFYYLLYVDFYNYFYILFDFYAFWIRYFF YY MY FFLFYYYYY YYFFYW YYYIY YLDYAYY YYA LLVFYVYIW LTLDIYFYTYILWDDYLKFKYYFFYII FK E7B EE TKVSTSKSSKSENTASSKQASVITTKSSSTSNRSSTSKNSSSKTSSTSTKTTTTNNTTSTSMTTTASQTRTSSTTNTTITTTTKKTKKNNTKSKKNTTK SRKTKFTRRVTTKNNKVTITRVVTKFVRTVKIT IITLKNTITKSDTINETTSITSVLSLTTIRLDTTV RVFTLTTTNSIFETTRT Q EVQSTLTYTVSKSTKVVSNEQEVVNEMNTTTSTTVSLTTSI ED SSTETTTISTTAYSQT EVVKATSSSSSQV IIKQRAEK SMTT TKKVTIKSVTTKTTSISRTSRTVVISN VE E8 EE VVVVVVIIVVVLVVVVVIIIVIVLIVVVVLIVLVILIIVIAIVLVVLILILLLVIIVLIVVLVILLLLLILLILLILVLLLLLLLLLLIVLLVLLLVLLMVLLVVVVLLILLLVVILILLLLIIIIFFIIILL VLLLLVVFLIIIVLVLIAILLVMIIIIVLIVILLV LLVLVLILILVVLLLIL V ILVILILLLLVLVVILLIVLIIVILVLVLVVVLLLLLLLVVLLLLVLIVVVVLVLLVLVLL LVVIVLLLIVVLL IIVLILLLVLVLL VLILIVIVVLVILVIFLVIVLLLLVVL LL E9BBBEE SSSSRKSKKSKSKTSKKSSSKTKSSTKKKSRKSTKSKSKRRKTSKKSTSSSTSRKSKSKKSSKSSSSKSSSSKKSSKSSSSSSSSSSSKKRVSSSSSSTSSGSVTRVGTSSSSSSISSTSKSTSTSSSNSSSI SSSSSSVSSATSSTTKTRTTSSTVSSSITKSSSIV STHSASQTSSSTSNSSS V TTSASTSSSTTSVSTNSKSSSAKASTSKSTTTSSTTSSSVISKSTVASAISITDSNTSTSK SSTSQSSSRRGSS KSSSSSSIASSSS ASTSSSSTTSSTSVSSTMASGSEKISS RK E8B EE YYYYLLYLLYLYLYYLLYYYLYLFYYLLLFLLFYLFLYLLLLYFLLFFFYFLFLLFIFLLYFMFFFFLFFFFLLFFLYFFFFFYFFFFLLLFLYFFFFFYYAHLFFFVVFFFYFFFFLFFFFFFFFFFFFFFI LLFFLFILFIVLFFLFVLVFFLAALAFFYFILFFA FAFFIFAFFLSSFVFFF V FAFVFAFFFAVFAFFYALFFFFVAFFVLFAVAFFFLYFFIVFVFFVMMAAFVYVFGAFVFF FVIFVAYFLIFFF ALFFAFFFFFMAF YFFVLFFFWYFFFLILYVIAVYLLALF LF E8BB EE VQVVVTVTVTTVTVVVITTEIVTTTQTTVTTVTQTTVVKTVTQTTTTSTVTTSVVVVTILVTVSTTTITTTTIGTVAVSTTSTSTSSTIIASISSTSTSVVTKNSQDSESTSSAASTQVQSTQQSQQSQQTTE QSQQTAEVQSRQSQQAQKRTSSSRAVSESIQQQQQ SSQTEVSLAQTSTSQLI E SNSQSSQSTNQEKTSSQTQQYQESTTSIQSLETGSRSQGLEAQQSQQQQRSENEATTQQET TSQANETKSETEQ RQTSTRRERRLQT QEDSRKSNRSISTLSVRERLSSTTQLT TA E7 EE GSGSAAGAAGAAASGAAAASASAAAGAAAAAAAGAAAGAAAAGGAAGAAAAAAAAGAAAASGADAGAAAAAAAAAAAGAAAAAAAAAAAAAAGAAAAAAGSTARATRAQAAAAAAAAAASAATTATAATTAAR EASTGARSSFSSAAAAHASAAVAQDAAKSAGSSSN FLSAQAAHAAAQAASAS H ALASASSDAVGAGSASSAAAASGTAAAASVAGAASGDSANGAASASSASSAGSSAWMSGAA ADSALSATAAAAS GAAAASASGTNSA YFLSTSAAGADAAAASYMGPAAYYASA YA 0B E QDPTEESEEKESEDQEEKEDESEPNAEEEPDEPEEPESEDEESPEEPHPSPEPEESEPDETPEQPPPEPTPPEDPSDQGPPGPSDGTDEEDESSTPEPGETREHETHREQPDSEEEPTPMQPTTETGTMMEPK TSVTPEHSVDETETTPERDPENEGKHEHNEKTVVE FEMPEDDTETNPKEVED E PEEYESVGPEGRESENIEMTEMKEPDDEVAENPATESVSNHGATEDTDASETSRDEHIGTD KSSESFTSEPVTT PTAELATNRPEVP TPSLKDQIKDNEPDISPTDLRDPPNSP PP 5 TTTTTTSTTTTSTSTTTSTTTTNTGSTTTTSTTSSTSSTGTSTNTTNTTSTSTTSTTQTTTNTTTNSTKSTKTNTSNTTKTNTTTTTSTTNTSTTTTTTTTSTDTTDSDKTNTTTTTTTDTLTTTTSSTTQTN DNDTHTDKDTSTTTTTNHSQTDTNSETDLTDTDDS NDSTDSSDTTDNTTDTT D SDTKTSDDTDDSDSTITTTETTQDTTTTDDDDKTNDSDTDDTTSTDDSVSTKLTTNDDDSS TENKDTSMTSTST QTDTDTSSDTNTK DDDTSSTDATDTTNKKELNTSNQKTET ET 7 AAAAAAAAASAPAAAAAAAAAAAAAAAAAAAAKASAAAAAASAPASPAAAAAAAAAAAAAAPSASPAAAAAASARAPAAASAAPSAPSAAPAAAASPSAPAAAPPKPSPASAPPPPAKPKPPKKPKPAKQSAP PAKKPPPPKAPKPKKSPAPPPASPSSPPEPPKKKA KPKSPAAPPQPPRPKPP P APPPPPKVSPPSPAPDPAKKPKPPPAPAKPPPAAAPAKAPAAKQGAPASVARDGAAPKPSS QPPPPKSKAGASK AQPSAKSAPKPDA PSPPPAPPPAGPSAPPGPPESGGGLPP GS H4B HH EQEESSETPEAEAQEPPAEEAEAGEKAAQTATEEVGSEGAPAEETAQKEEEAAPTKAESSEEAKKEPNHAGDTQEKQEEQESGIEEEESPQEKVVEEKEEELSQKQEQEKEQTKKKVESADTEEKEEEEETIA VKIEQKSEALAEIEQEQRAAMTQEEDVGYLVEATA EREKEEQQKLAGEEIEE E ERASEEAQKRVEALKSNSNAIEENEGQPDQKVQTKARAVEVELSQAATSTKESEAEQAVKE KADVEEIEAEQKE SMQESEKEVMQLH AQQDEDEEVKQKEAQEEVQQQKMMDAE VE H8 HH GADGEDADDEDDDAGDDESKDGDDQYDDDDQDEAQDDEDQDQDEDDEEDQEDDDDEDEEDGEDKEEEDDEEEDDEKDGDDEDDDDDGDDDDDDDGEEEDGGEDEDGQELTEDDEDDESESSESSLSEQSSLEE KLSSTEQLSSQSESSRTDREETDLNTEQGETSSSK ELSERREQEDLQGLSDS V ALLELESRELRARKYGSDSSESVQEDTDSQQRDELVSSEMEEDSAEKTREDVGLEGQSRLD SAQSRSKSDKDLS KDTLSSNEVSTSD YELMLKNLLDLYEADLSDQEEDEDDIE AM H9 HH AAAAAAASAAAASAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAAAAAAAAAAAAAASAAAAAAAAAASAAAAAASAAAAAAAAAAAAAAASAAASAAAAAAAAAAASASAASSASAASSAAA AASSAAASSASSASSSAASAAASATAAALAVSSSG AASAAAAAASAASASAA A SAAAAASAAAAAASAMSASSASVAAAAASAAAAAAIASAGSASSAAAAAAALMAASASVAA SAAAASSSAAASSMLSAAGSSSASASA TSAASSASIALAASASGAVVAAGGSAA GS H9BBBHH QQQQNNQNNQNQNQQNNRQSNQNQQQNNNRNNQQNQNRNNNNQQDNQQQQQAQNNQNQNNQQNQHRQSQQKQNSQQSQYQQYQRQYHQNNSYQRHYQHYQQHHAQFAHAQQYRQQQQYQLKQFFQFQQFSQQA AQLFQQAQLQVYQFFLAQVQQKFAKAQAKQTYLLV AASHAQYAQYKAALLQQ A LAQGQALSHATHVQQKYNLYQYAAYQLNLAATQQQSELQAAKYYQTVKAVQARAKFTLTHK AVAQALHASAQYFKAYQQNAAQSAVLQ AATTSKQYAQKQQSLQHKTAHQAAFQY AL H9 HH MKKRTKKKNKNRQRRNNKKKTKKTKQKHNTQQQKQTNKNQQQKQMVSQKTTKANNSTSQTRDIQDEQQRKEQQNKENMNRKNNDKKEKQNNNEDDDKDNKRTDRLDKAELTNDDNSDTDTDDKDADQEEDDDD ELTDDDESTTESDDDADTEDDEDENYDDDENSTTE STRDSHKKEKKQIQALE N VTDNQKTRDTEDVHSDTKVSNSEQDSANTKDERQSEKTQKELNAQEEQENKTGEESKVEDA LKQDQHDENSDDDELNQKQELLQLETR KESQSSKDRNSSTRVSREIDANSSKTD SA H9 HH KKQRLLQLLTLQLGQLLTITLQLVTKLLLVLLVQLVLTLLLLKVLLIRVTVLVLLQLVLLRVLEVVVLVKIVLLVELKLVVLVLTLLTLLLLKLLLSVLQRFLWVLWLWEVLLVVVLLLLLLLLVLWVLLTLW LELLTVWILTWLTLLMWLWLTLMWWLTWVTWLLLL LWLVWILWVLNWNRLTV W MWTWRWLWVWWLWGVTLLLLVLWWLTLLLWWWVREWNLRWWRLLRWWLWWSWIWRFWLWLL NLWTLLLLLWLLLIWLMRRLLLWLWLV WLILWITAWLTVVLLIIFWILCVVLLL VM H9B HH LLLLLLLLLLLLLVLLLLFLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLALILLLLLLLMLLLLLLLLLLLLLLLVMLLLLLLGLLLVLLLLLALILLLLVVVLGFLVLLLV LVLLVLLLLLLVLLLLL V LVLVLVLLLVALVLLLLLLILLAVLLLLLVAALLLVLLLIALLLLVVLAVLALLLLVLALL LAALAILLLTLLLLILLLLLLLALALL LLLLLLLLALLLLLNLLLLLLLVVLIL VL H9BB HH AAAARRTRRARARAARRATERNRKDARRRERRAARERTRRRRAKRRNTNNASARRSRQRRANRTSSKNKQNTRRASRATSANEQQSQERRRNDQQSLSNAAQLKGTKQRASAQLLTDNSNQETTLTTNAEKNQSSTRSRLENNNHNGSGKNAHAGIKKDDGRTQSNNSG TSSSRSQMTNQVRERES R ESKRVKNESSKKKETSTRENSNNASQTRSVVKKETRQNEEREQKVRKDNEVQAQEAGNKVK QDQKNNSNKTSVSSRISTENNSANKNK NNNDNEAINNDTSSQNNTKNQNNNNNS NE H9 HH QQAESEQSQQQEQEEQQTQKQQQGKEQQQGQEGQQGQSQQRQQGQQNKGTGQGQQKQGKQEGQKGGNEEVSDEQGKQQGDGGGGGGGGEQQGGGGGAGGKEGGQQAQGRDGGGDDEGEGEGGDSDAEGASDGKGAEELGDKDDDQEESDGRDQGKQSKISERGQQEEDK GNSGRGGQEDSHDKEKG R GNAAKQDQGSAADGEGAGSEKQKAGQDQQARAEQELSDQQNQNHKAANLRAAGTQGAAAAN DAEASNEAQTDASGQDDHQEKQAEINE GAQGEAQEQGGEGDADGQQDGGGDNGG GG H9 HH YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYVYYYYYYYYYYYYLYYSYYYYYYYYYYYYYYYYYLYYYYWYYYYYLYFYYLYYYYWYYLYYYFYLYYFYYYYY YYYYYYYYYYAYYYYFY Y YYFYYYYYYYYYFYYYYYYYFYYYYYYYYYYYYYLYIYYLYYYYYYYYYYVFYFYYFYYYY YLYFFYYYYFYYYYYYYYYYYYYYFYY YFYYYYFYYYFYYYYLYYFLYYFFYLY FY H9BB HH IIIIIVIIVIVIVILVVLIIVIVVIIVVVIVIIIIIIIIVVIIIIIIIILIVIVVIVIIVIIVIIIIIIIIIIVIIVIIIIIIVIILIIVVIIIIILIIIIIIIVIIILLIIIIIVLIVVMIVVVVVLIIIIVIVLIIIIILIIVIIIIVVLIIVVILVIVIVIVIVII MAIIIILIIVLVIIVII T IAIVITVIIAVSALVIIIIIIIVAILVVVNAVIIVILIILLIISIVVIVLLVILILNIVSI VAIIIIIIILLSIIIILIIIISVIVII IVGIILVFVIVVIVLLVILVIIVVILI VV H9BB HH QQQQADQDAQAQDQQAAEQTDRDDQESAAQAEQQANADAADAEDNAEQQQDDDVADAHEAQQAQNHDANDNNQQQNQQNNDKDNSKDSSAQNTNNRNNDQQDNDEAEDAADKNQQSRTRQNRLSNLTDLSIRQDANQSGQGIQCAAQSLDSVARQDQANEKKNTEGQQE NESNASKQNAIEQEQAD E DETRDQQENEQSANNTEDDDSEKERTEAQEEKNAAQSQAADDAEAQEQEDNRDAADEDKKD HNHKAENVANRESDNADDALKKEAGAN HVEESIDKHNKNDRDINQHKDNASKER AD H9 HH QQQQFFQFFQFQFKQFFKKEFQFYQEFFFFFFYQFYYKYFFFQYFFFTYQYFYFWNFYFFQFFTYFYFYNYFFFYQFQFYYFYYVFYVFFFYKFYFKYYQQFYLFFLFDEYFYFFFYSYFYYAFFFKWAIFYMYQFFIFFISFHRIYFMYMYRFFKFDLMFLYFLIFFR YMFYDNDMFMSMFFFFN D YLKNFMFLYMRFRYFYFFVFTMMMFQRFFLMRYFFSSFFRRFYLFRKVRVKLYQFYLFRDH FTRKEFFYFQYEFYMMYFFFFFKFRFY YYFYFFFLAYYFYFFSAKVIFYYYFAF YY H9B HH VVVVAAVAAVATAIVAAIVIAVAIIIAAAVAAIVAIAIAAAAIISAVVIIIAIASVAIAAVIAIVIVAAVIIAAIVAVVVIVIVVVIVAAAAIVVIVVVVVVVAITAVTLIVVVVVTVTVVSTTVTAVTTSTVIALVTVVAFVIAIITTIVVATILIAAVIAIAAIVVA IATVAIVVIILAIVVTI V IAIAVAVSVAAIAIVVVAIIVIAAIAIAVAAAAILALVIAVIIIIAATAVVAVVIIAIAII IAAIATIIAVIVTVAITIIIVVAIAIA VAIVAVITAIVVIAIFTIVAVVVVTAI VI H9BB HH DDDDNSDSSDSDSDDSSNDNSDSSNDSSSSANSDNTSNSTNNDSNSANSNSNANSNNSNNDGNNSASNANSTNNSNNDSSSSANNSKNNSNSNNKSNSSDDAKANEAAANSSNDNNAKANKAEENEGNEENAASGNNETNVDNSSENEEVVNSANNDAAASANGGKNNS VAESANNSNESGKQNSN A IASSQGNGSASTGNSNNSESNIASSNNSNAGSAQNENNQQTQSGQSRNAKNANSQDANSSS KAGSSNNSNAGSENNEAQQGSHSSENA NLIIHNNNMSNNSSNDARQEASLVKSS LV H9B HH DEDEQQEQQEQEHEEQQQERQEQQKQAQQAKKNESAEQEHQSQAQQADRKAAAQEAASQQEQEASQAKLRAAQQDYQESLASATAATAKQQSNSTTKSSDEKKQQYQAEQASTQQQTTTQESSSQSIALTNSKAEKQRDQKDQDDRHLSKEADTSAEDKGNERKQRQQE SEASERNNAKDDSQQQQ R KEQVQDQKSEEDAEQEQQRQIRDETSDQQDEDLQQDTQQQRSDAREVESQKDKEQVQQGDS REKQREEKAESNLRNKQKQEEETEAKL NVEQQKEQQARQ QADEIALGAEENAT EK H9 HH KQKERRQRRGRNRQLRRRQGQQRIQLRRRLRRLQRIRRRRRRQIRRKEIRIRIRRDRIRRERRQLRLRAVLKRRIVRKVALVIISVISRRRVNTIKELVQERIRYQRRHQLVIWWYLVKNSKKKFKNLNKKQQLAKAKKWRKTTLKRQKLKRLKKKKRSIKGKERKTTL LRKLIVQDTKDRKQISV R LREAQRTYLKAQAIYQKRNKSKKLKLQRTNQAAQQTLIQLRLIKQALKKNQRKDQKSQAKL RMLERKKTRDNKQQDKYKGNQRAEMKA QKSLQEKHAIIY RLKQEQKRILLKKK LL H9 HH VIVVAAIASVAVAIVAAVVIATAVVIAAAVAAVTAVAVAAAAIVAAVVVTVAVAAVAVAAVAAVVVVAVVVVAAVVAVVVVVVVVVVVAAAVSVVVTVVVVVVSLISVSTVVVVVIVVVLAVVVVVAAVVAVSVATIVTVSTLSAAAVVQTVAVAVVSSSASVAAALLA QAVVSAAAVVAATQIAA S QASAQALAVAAVAVSVLAALATSAVAVAIASAVETASIEASEVTQSATTATAVAEAALAVV TTASAVVVAAIVVVAVSEEVVVAVTVV TKYQFVAAAFTS AMTVTTTVLEEYTV EQ H9BB HH NANAAAAAAAAAAAAAAIAAAAAEVGAAAERTVASEAIASASAVIAVVEVVAEAAVTESAATTVVNVAQVVVTVVVVNRQVRENERNETAVRVNNRSVHNAEDMLHMVVRVQNLLLRFRNNRHRLHRFHHLRIVKQNRIVMKNFKHFRHQEAKRFWHLEKFMNYQHNNK NKQVITVSLKRKHLNYT L QKLKLKNKVKERENLNNSRHYHEKRQIANKKEQIQRQNIMLSQRIKVFRISVNRSKKNERVRHKELLTNKVTRRRSKQQVIRKKKKKTQ KLDHSKFIRDYL VMKWRLIVNRRNLR RQ H9B HH QKVKTDKRRKSKQDKTSSKGSKQQQKQSSKATTKTKRNRANTKKTSTDQAKQKARRAKTSKQTDRQKERNKSANKKNQDKKEKAKDNKFSNDKANVSREEKSADNQDDQTKEAAANKNEQAQQENQDEEQVKDKQSQETIQFQNQYANQKATQEAKRQQNSKDQRQQQK NSQRQETQTAKKEKQQK E QSDNKRQERNSDEKNNASKRQREEMVASQHKSRVQKQQAQTARKAAGSQNSHANANRQSDDNESQDATKDALQDENKANAAETNADAAR QEAKKNESAEQN NEFSKTQDERQSAM RK H9 HH EEEEHHEHHEHEHEEHHEEEHEHEEEHHHENNEEHEHEHNHHEEHHQDEEENEHHDHEHHEDHDDDEHEGEENHEDHEQEEQEDFQDFNHHQEDDESDQEEDDEQDEDETEEDEEQRDQQYQDDQDEQDDDREEERQEQQEDQFEDIDDQEMEQVSKEEEVENLENQQE EEDDEILDEDQESRQLT E REYESEKEDEEEESQDQHDDIDGEEKQHQEEEESNERQTENADDQEEVDNSEDAIVKQEEEASEEYDDENAAEEDNSDVAANTNENEGE EEREEELQEKQQ VRDEQKQDREEDDE EQ H9 HH LLLLLLLLLLLLLLLLLLLILLLTLLLLLTLLSLLTLLLLLLLTLLSFTLSLTLLYLTLLLVLYLVTLVATTLLTYLLVVSVTVIVIILLLVIVIVFLVLLLIMTAMLMLSVVNNTMAFLILAAIAVVAASFMSVLLAINMLLSLAEAVLMALFEKVMLMEMLEVALLI LLALMSSMDALIAKLEIMM VLNMKVLLLLLAMFTVLLAVEAMVVIDLLVLLVKLVLFKIIKAAKLVVMMYVVLKAVLLLTKALINLLVQLLILVIMAMKKQQILQLLV LIIILLDILLET LILLIIFLLIIVTV IL H9B HH EDHENNDNNNNANEDNNDYENGYMDVYNNMDNLANINNNNNNILNNLGMDINVNNGNLNNELNSMVLNLKLLNNLGNEKIIKVFAKNANNNKENNKYMKEERTRNFRRVYITFKKNKLKNLKFFNFIDFFLKLIVYYFQKQYNKLLLFFIKRLKLSIMILLQNVILNNK CLFMLQLLKFDILNKLREI VLFINLNIMLIFILNNNNLILLQLKFENNLIILSYIYNSNLGLLNIVNALYINIGILTIILNLVIFEIVFDFKIFNKIQNSLVILFVIL LKKITYKLLNIN NRYKTLYRNAALLK AT H9B HH RKKVEDTDEAELELGDDEVKEVDEASDKDQADELDQAQDEEDDDDEEGQDEDQEDDQENEVQQAEQDEEDDEDQEDQKDAEEQRSDLGEDQNNLLDSESKVYHGQNGYKQENRKKQTNKDFVNSKNEKNNNTQERQDNQKEEANANDDNHAQANETNAAKEDDESNDAK DSNENQDNIRAQRADENVE HSKKAKQAESKSSNQRQDNNDNTTDEADNEEKEKQKAAKKNKQSKKGSDRSDNKKSENKDRDQKKKKQSEASADDYSKTGKENDQKEDE QTNSNKNKDNEQ SDENTNQYTDDLSD EH H9 HH DDDDEEDEEDEDDDDEEDDDEDENDDEEENGENDENEDESDEDDEASDNDNENEEDEDEEDNEDDNTENDYTESNDNDENNENKKEKKQENEDKKENDEDDRKNENNNNTNEKDDEENDDKENNENDENNEENNNADNEDGSNENNDHDRNTNDDENNGNDAQNNNDND AGNDNEENDNLDNEDNDDN RGSNENDDDGNVNYEQDENNKNNGENEEDSRNNESNANENHENNENSETINSKDENSDNANANNNSNDSKNDEEHNKNQEAKKDDNNDN ATQVNKENT NE NQSRDNQNDDDSDENDR H9 HH LLLLLILILLLLILLLLLLLILLILLIILILLILVILLLLVVLMLLIIILVLILLILIILLLLIILLVLILVILIILLLLVLIVILIIILLLIIIIAILLLIIAFLAIAAVLIFFFVLILLILLFLAFLLFIAVAILLLFVILFVLFLFLLLVIFLLAVIFVIFALLLMMLALIAFFAFLMALLLFFLA LTFVLILAIAVIITFILILLFLQHILFLLNAVLLIALFLITLLLLVVFAVAAIILLNLVLLVLAVFTLLFLALLLIHLLLLFFVAFVLLLALMLLAFRL LF LIMFIIIIILLLIILVL H9BB HH KSQKTQNESSTAQNQKKNKTQKERQDEQKRQKRKRRKVKQMKQRKDRKRKRKRANKRRRAKRSMRRRIRKRRKARKAKNRRNRQQNQQKKAGTQKDSRSKKQKQKQQKHARNQLLKDQQFQDHKKQANQQNDRRRWFQHLRGIIRQLEQTLEMQLKVYTKLQKLTQLIGRERQRHTDRLQYRQQNLYKQ SRLVQYVRRRTATKKKAQQTLKLRDFQKFRVTREHSQIESQDNQNTNLASAGKEGARTTNTRQLLLRRKLAENDEEQEQQELSKTLTRRARSDEQNQQA LK RHGAFKLKKEEEEDLE H9B HH DDDDGGDGGMGDGDDGGQGSGDGNVIGGGNGGNDGSGTGGADTNGGDLDTNGNGGRANGGDYARNYSAASENGGNRGDDSNDNRRDRRGGGDYRRDKNDDDDRRLARNRQNERVALNANSRNAALARDAAINRNAQNAEARRSYRAVAAEAARNVTARKRVRFIKASSSNNSANRNQSAASASSSINDR ESIRSSSQNSTSRGQLAGAATATSDENGNSSASTQRSSTSRTAASTRNTNKRFQTSSSTAADSSYIASSMGKEAALQAELTLLSRLRSAEVGLNASMAG IQ ESRRTQSNNSSTGDES H9 HH NNNNAANAASANATNAASNNANAQNNATAQATKNAQANAAAASRLATNQSKAQAANAKAGNAASKSDAITEDTSQSNNMAKMQAQMALVARMNAAQAKMNNQTEGMEQEAKTANNGAMATSMVFGMEQIVVAEKESTLADELIWEIDLVQEQEADITEEDDETDEVTTEQNDAKESNQDTSDIIINDNE EDSEIDTVKEEKEVGVVAIIDVEEQRNATDDETISETIIEEIIIIEESEQADISIIDKEKKAIDEDQIDFRAKKLISTNIIFFREFETIQNKANRYKEE QG EDLARQKQKLLFAQAL H9 HH IVIIWWIWWMWIWIIWWIIIWIWIIIWWWVWWLIWIWIWWWWVLWWVLLVLWIWWLWLWWIVWLLVVWVLVIWWLVWIVVLVIVIVVIWWWVVVVILLVIIVILFVLLILLVVIIFIIILLIVVFVALVVFILLALLVLIFILIAVFVIRIRVVFLIIALFFIFAVLLALRIILILVLILLAILLLLII RIYAWALILIAIAKFIVWVIFVILITLWLMFAIWLALLWYSWIVWAAIINLFIIWVMLAIILVAAYVLIVWIIIVLILLWWIIIALALVRKVVRIKILV IF WLINKNKLIVIKKINV H9BB HH ATATAAKAAEAKAKKVANENATATDKAAATAAEKDTQNRAAAKDIAAAIDEAASQGAFAATEAAEEDAEVDEAAENEAHDEHADDRDDLAAEGDDEQEKATDDENSEDEDEQDNNNSNAVASSNNSQNNNQSDESEVSQSQFTKEDQFNDGREAQKSESHQEDNSDAADENSSEEENSKDRLDQVNNTE ASNQQLAEESSAEKNERAKSNGGAERQAVLKSEQEEQTHDEQNEEAEQSREQDQQNLTSSRRDSDNNKNEAAASFD EAQQDKVDDQQEDAQTNHNANA KN QDFQQSQDNRNRQEDN H9 HH LALLAAQVATALALLAASLSAQALSSAAALATIQTLAAAAATSIAALVLAITLAAVAITALLAIVLVTLVLLTAIVALQLIQLLLQSIAAAQVLSRVVQLLQRVLGVQVTIQLLLLRGQALEGSLSVAGGERVIVQAVLVVNAEVSNGGLTVVQNESVVVNVTEVGSAVISISVVATMIAEVANAESLV LIEVNVAGVVVHVSLTIASTESTVREAAAVVVLNLVEANIVNTSNVVATSVVTLNGIVVYNLAMVENINSSLQYGT AANNSASVSVILLLASMAIQTM QL SLNAFVSQINNIIRLN H9 HH GRRQRRQRRRRQRRQRRNQRRQRKKRRRRKRKKQRKRTRRRRRKKRKKRKRRKRRKRKRKQKRKKKRRKKKRKRKKRGKKKKKASKASKRRKRAAKRKKRQIEKRKKTKRKKAVVRQQQKKKKKRKRQKKYQKKRRKKKVKKKSGKVEKQKRGQVEKKRKVKAVLKKKLKQMKKKQLKAKRKKRKVKQK QMKRRKKRKVRNRVRTERKKIKKKKRMRKKERKRRRRKRERRKKQRRWRLRRAHRKKKKSKEKRKKKKQSRQQSES KARRAALRSRKKQAEQNAVQVR KR QAKKLLRTRRREAKER H9B HH RVMTTTTTALTTTVTATIIVTITTLATVSTTTTITTAMTSTTTTTTVETITSTTSTSTTTTFSQTSKTAKKKMVTTIRLSTLTKLLKLETILTKRLMTLMTLKGLRSLARTLKLLLLHLYLLKRLRAIRRVLATAKYRIGNIYIARLRWLALALLVEAGSLSKVARYYATHASTAILAIQAAQIYLITEMLALAIAQKTAAKAALKTTRKIQAALIITYAAAVIKAAYISVLKRVAAVVAMNKVIFAHAQSVQAVLRNMKLLLQRKLELMIKKVAKAKALIILLQVIIT IL WIKIMVILKLLLGLKL H9B HH KKKKIQAQIATSTMTTIVIKISQKESQTARVQRTQKEKDIVQRHTVQRKSQQNVARISQAKAIRNASQKKDNQRRRRKVRQANGSVTSQVRAKGINDNNKKTNRDNRARHQEGSSDINVGEINNDNRLNNKIRQQSGSKGRNGSRNTNNDQQRVTANRRVARKSRNVGRRSDNNRKVDDVNDDKGSAKRKEDTRKDVSNDRQRTDKQQHQANQESALVGDDRKKHRHGKQRKNNKRRNKHQAIRKNDNRQERDVRGRHKQQQVQNKKTSKKNQSNQQNKDDLNTNNDLR KD RQIAQYGANASLVSRA H9 HH NESTQSTSQDQTANTQQSTESASVDNSSQMSSFTSAQDQFSSDFFFTETDFSVQLEQFSQTVQEVVYSSETVSFYESNFVFYVISYMSSQFYEMMHAVYNTQLNAENRDAFYIGGEYQYEAYEEAENSEEAYNFVQEETGNSESNESEEGSTNYAEEDDNANMDNEEENYVNEVDINSNQSNETEDATDNGNDNANELVNNINSEISSEEDESNFTAQENNNSISNTEINQTEEVNNTSDAATNTGNQNIFREMSDEERESNYIETEQAAIEALARNESGANQNNENQS AE QPAQNLR SSNVFLS H9 HH LLLLLMLMLLMLMILMMLLLLLMVLLMIMEMMELMVLLLLLMLEIMELVLELVLLLIELLLELLEEEMELEEMEELELSEESVGESAEFMESLAAAIESLLKSILLIEVVESGFLLSLALEALLLLIRLLLSMELLILELITLLVLLLLMILVALLLVLLLIALQLLLIELLLEIRLVLLLLLLLLALVLILLLLLLLELILLLLALMLLLLLLALRMILLLELLLLLLLLLLLLLLLILIMATLLLLLLEQLLLLLLLLVTALLAILGILLLLLLLLEMYLYLLLLTT LL VQLLLLE LLLVALL H9B HH QQQQKKQKKQKENKETKKNTKNKEKMKKTKKKQNNEQKQKKQVKRRKVQKKKEKQTKKKQQKKGKKKKENRKKRQKRQQEKQATEKMEKKHESTTQNKEQQKIQKTQKDQKQTEEKVRNKQSIIKISQVTEVRKNLEVKEQKANEVQFTNERENQEHEEENQTTQITTRQLDLKEQNLEQKEDTRTKQEQSDRDTETRKAELGNRAQKIFNISQKQKKEQQEELQNQALHQQLATEAQRENQTEQTQSEQKENDDRESTEKEKELNQKQALQLEQIEFEKHQKSLNTKQ KR VKNIQNK QDKAKQE H9 HH DEDEAATAAKADADDAADNSADAQAEAPAEAAEDAQASAAAAEESSDEQGEAQASNAEAAEDAEEDNASEENAAENADKSEKQDAKDSTAAGNDDKTEGDEEEQFQQAQQEKDVVFEQEQREQQFQQTQHFEQESQQQSIQKQYQQYQQTREQEYNQRLQYQEYLQQQQELQQEQQKHLQIQLAQYQEQDTQFQAKQSEQQAQLFEQAQQYQRWKQKAQMQQSSRQLQAQQTQQVQQKSQTSERTQSQQAKDLKRFEQEIARGAQEQQSTSVTVLVRQSTKYVTLENDL YF NKTNQDA DMKLKDM H9 HH SSSSQQSQQSQSQDSQQSTSQSQQSSQQQQQLKSLQQSQQQLSKQQASQLKLQQQTQRLQSKQSIKVLRTSVLWKVWSSRKMQKKLEKLQWLIKKASILSSQKQAQQRRRKMKQQTAQTQLSQQTQQDQQEAQKQQQQGQQEQEQQEQQEQQQSEEQRQQEQEEQQQQQKRQQIRKERQQQQQQQEGSRSRQGQQQQQIKRSQRSEQQQQEQQEALEQQQSRRQRQQQQEEQQQQRQEQRAREAQEQQRNRVQEQQHRSSLDKNQERQQQQSSKESQQSEQQWSTDETQ QS YKRQQRQ EKQMSEN H9 HH LLLLVVLVVLVLVLLVVLLLVLVLLLVVILVVLLVLVLVVVVLLIILLLLLVLVVLILVVLLVLLLLVLLLLVLLILLYLLYLYYYYYVVLYVYYYLLYLLYYIKKIYILLYYKKKLKFEFLKKKKILKKHLVLIIEKLKIMEKIKKKKYILIFKKSIIIKIYKIKEEILIIKLIIIIKKMIKYEKKLILYILIYIQILIIKIFKYKVKKKQMIYAQVEIIILYLIMEYILYKKYIIRVMLIYLFKIYIKLVKIIFILTVVLYKKYIKYYYLQNLIILLYIVAIIIKLS QK E LIIIY LMLLLLI H9B HH RSKEKKQKKAKKKEKKKNSQKGKEASKKKEKKAEKEKDKKKKSAKKENEDAKEKEDKAKKEQKAAEEKVAAEKQANQREAAEESEDSDKKQQSSFQDASKEQNDERDQQQASSNNEKRKKSKRRNRSHRKQKDANKNKANDDKEARSMKREEAKSKIYDNSDNIDRKKAARRKAQAIQDTQRRDTTEEDKVKNNDRQVAKVETDEEKKKTIRDDEIQKNDDLIDNVQKDVKENRETNQENDTREERSSVLERRSANEEVESKALTQDINDDQRDDEAEVRADARQSKKD QE Q QNDSQ TEDP KE H9 HH TSTTRRTRRARTRNTRRANARNRLTTRRRLRRQNRLRTRRRRTLQQLSLTQRLRRTRMRRTLRLLLMRIAMMRRMTRTILQLLMMIQMRRRVLLLMALVTTLLTQITLTAQIMKKQQIQNLRIIQITNIILNIQTANILKISNVAILVVIVLTQLLMVTILILRSINNSMMAILNDDIKIAAISNKITSTLAQGSRSVLASSTIQLSRIMKVAAMNDRYASSLSAAANSSTSAMNSADVIAVLESLSSSAILIGDQASSMREIAVLSIVSSMIVNILSIISKNLSIETV QQ S VARSR AAYK VA H9 HH QQQQQQQQQQQQQQQQQQQMQQQDQQQQQDQEDQQDQQQQQQQEQQEQDKDQDQQYQDQQQDQQDDDQEQEDEEDYEQDEDDDEADEAQQEDNDEDQDDQQTDLMLLTLQDDEIIIDLELEELLILLILLIDLDLFLLEILLLILLILLILELEILLLLMILAFLLLLLDKALDLIIVILQELVLFLQLQMAILVELMDALLLKIALQLLFLLADTIQLQALDILLQLILLALLLLLILAQLAKALELLLDKLKLILRLSQKELLAALAIITVLLTLREMLLMRKEILV II Y GVAV LQNQ LQ H9B HH EEEEEEEEEEEEEEEEEEEEEEERIEEEEREGREEREEEEEEELEERSRVRKREDTQREEEREVEKRERLRRDDRKDELRRLRLLLLLEEELELLLLELEELLREERLRERLLEEETEVYSVEEEEREEEETKRREREIKRRQEREQEEQRRRVQETRRRQRLERELQRRTREEREDKQEERVKQEEEREQRKRKQLKERREQKELNEEEEERQLQDERKRRRKERELKRRRSTRRRIRRIQLTKEKQRDQRVRRKRKKEELLEELRELKKEENRKRERQRKRTKKEER TE V EKRR RRIY RR H9 HH VKVVAAKAAAAVATMAEKKHEKEVKRETAVEMVKMVDLDAAMKIASAQVKIMVARQDVSAVIDKIRVMNGEAMTVKAVANISVLSALAMEANQLLEQINVVELQETQQEAIALRRETTTQQSSSETEFSAQAEIETQSSQEIQQNSESTETTNTEFKEEAEDQRESQQDVEASIERFDRSNEAAQRRVDVEAQEAEQRIAELENEQAATLRRAAEKFEQAAENAAENQTEEALDREEFEEKNQYIDNQEAAIAEEQVEIVSRAASQASVSSQEEEKELNEMETDANENS DE N DEEQ AASR QA H9 HH VVVVVVVVVVVVVVVVVVVVVVVRVVVVVRVVKVVRVVVVVVVKVVKIRVKVRVVVVRVVVNVVKNRATVRRVARLVVRNKRRRRRRRVVVRIRRRTKRVVRRVSQVNTIKRKDDNKQKQRKQQSQSKQQTKSKSSQQEDTNQDVQDKHDSRVKDRQTSMDAQDSQQQVRDTQKNDQADQSSQDQDAVTVDTNSDSQTKSTKATNKQVQQDQTSRDSVQSKKTDSRNQDIFDQQDNSDSMTMQTDQSQTSKEQVNNSLNKVIASKQTQRDDKKANRNLKDVEGDNKSEV QN H KTTI ESYV KN H9 HH AAAAAAAAAAAAAAAAAASAAAALAAAAALAAIAALAAAAAAALSALALATALAAAALAAALAAMLIALAMIAALAAAILTILALIALAAAVAAAIAIVAAWAVLAVLAATIATTLIAITVIAALAGLAALIATGAAALAAAAQSALAATAESILAAAGALAVLAAAAGLAAAIALIATAAAATTLAAAAAAAATAAAIAAAQALAAAAALAAAITLAAAAALTTGAATGATAASAGVAAAAAATAATAALLAAAAAIAVNTLAAAAAATTAAVGVGVLTYYYAYALLG LL E LAAA LYTE LY H9B HH QQQQKQQQKKQQDQQQKSQKSQQTQQTEQTQTRQKTQKNQAKQKQKAKTKRETKQIKKRKQEKQRETQAENAQRKQRQRVKATRKTKKKKRSIKKAERNQQKKKTKKRKKKEREETQKRQQQSKTALMSNTQKKKKQNQEKIQSQASRKKQTQRSEQKSKSKEAKVQQLKRSKRKNKKEKRRELQSNQKQKSDSLRQERGQKNKTKQQKKREERADQXQRRQALKQRQLDKLKLVQENKKQKQELKRQQKETKRQNNAEQKEEKKERKELLRKKQAKADRAKLKHKVTQ MT R LQKS KNLA QE H9 HH EEEEAAEAAEAEAEESAEEEAETNEEAAANAANEANAEAAAAENAANENENSNAANANVAENADNNTANETNAANDVENNNNNNNNNNAAANDNNNANNEENNEENENLRNNNTTEINSLSTNNENKTNNVIENKDLNNNAKLIKNVNSRKIKTVTQLKTVANIKNLLKNRNSNANSVSQAKSLLITEAERNVRLRFVNNREQYENTANKIIKKNQALLRLRNTERALQKIKQNQRKAKEEGNLKSKLRQSNSKKIDRVQAQNQNNAQHHIRNARKVQNRQGARSNVEV LE V AKVD TADV VA H9 HH QQQQIVQVIQIQVQQIIKQKIQIVQQIVVIIAQQVIVKVIVVQQIAIKIKQLIIVQIQVIQQIKQQKAEKLAAVQKAQMQQMVNAMNVSIAIKSNAKQIQQQKRTQRDRKQTNVVAARERREQQAQMDQQQARQQKGQTARKRQEKNRQARVEENDRRERNREQVKRRDQEQQQRQERVVQQIKRQTQRQAQQEKESRQQLKIKEEAVKQHKRLANDAREEIEQQSHRQTRQNRKVVKLQKRELQRERVQILNEVQQKKKLTAKRERVQRQEENQKAQEAREANNKQQE EA L EHEK RRIF RS H9 HH KKKKYYKFYKYKYKKYYRKQYKFHKKYYFHYYLKYHFRFYYYKLYYQKHQLYHYFKYMYYKHYKLHHYHKHHYYLKYKRHLRHQQRQQYYYQKHQRKLQKKQQRKLRQRQLRQRRKYLYLRYLLKLRRLLRYRLRKLLHRRNLRRLKLLLRRRYKRLRRRKRHKRLLLRLLRLLRRKRRLRRLRLRRKRKLRRRRRLRLRRQRFKQLFLLKLRRRKRLLRRRHLERRLQRKLLLHRRRRRKRQRLLRLRLLQLRRRRLQLLRNLLQTLRRLLLIRLKLHLLRKLLLKFR KK L RRRR RRKD RK H9B HH DDDDDNDDDTDDQDDDDDDQQDKNDDNKDNQDDDNNTDQQQNDDNDDDNQDQNGQELENDDKDQNKDQKNDEEDDEEDGNDSNKEAEDESDRNEENNNEDDQDTTSTQEQDSKQQKDADQDDLLTLEQLLNDADEQKLLQEEHKELSLAQEQEDSNIEQEAEKKEVQQEDAVQNEQLEQSDEAQQSQDEDQVNEQDQANTEKQDKKKDLESIEENATTQEDEKKQEKHQENQESQEEDEYADKKQKEQEAAQEEEKRKHAQNRTLKLEEQQAAKEAEKKQQNQKIDENR QK E EEHL TTKK QE H9 HH LLLLRRLRRLRLRLLRRQLERLRTKLRRRTRRALRTRKRRRRLARRTQTKARARRHRARRLVRRAVARIQTARRAHQLVIAVTVVTVVRRQAHVVVRAALLVVDVVDVDQAVVIIVVVVVVVVVVVDHVVVVDADQVVAIDIVVDVIVVQDVDVVNVDDDVDIVDVVVDARDVADVDDVVYDIEVVILDLQDIDEDVDADDADNVVQRVIVVDDVNNEVDDDIDLDYVDDDDVVDDDADDRDVDDIDVDSTTVDDVDSARRDVTAVDVQDDVSLDLDLIQDRLNELQNF TV Q HDDD NHLP NN H9 HH RRRRQEREQRKRERRRRRRRERTNRREEKNERNRENQRQEEERKEERRNRNENQRRQNQQRNQRDNNQARKKRTNRERDANGNKSDKNRRENRKKNRDNRRTKRQERKRRNNKQQQKEKERKEEQELSEEQKRNTREERQRKEQSEQEEERSSKQSERSTQRRQTEEESNEQEDRAKRQERREEEQNRRRDQRRERERDQRLSEQREEEEQERQNYQLESRRADHLREDSRDEEQRLERRRRRRDEREREKKERTKREELERAEEKRETYDLLEKLLEAERTREEINEE YQ R RKRR RRKH RR H9 HH IIIIILIVVIMILIILMLIEVITLLILLVLLLIIMLRLQLQMIILLIILLITLVELLILLIIVIIIIIILLLLLIILIIIIILIIIIILVLVLIIVLIVIIIVIVTIIIVIIILLVIIVLIVTTVTIITTIIIIILLVVSIMLIIALILIIVIVLIKIIILIILIILLIIIITIIVIILLIIILLLIIIIVILILILLIVILIKVVTVTILIILVILLLIIIIVIVLLVLLVIIIIIIIILIIQILILILAIILILIIILQQILIIMLLLVLLVILIIIIILIIIITIM LV I LIIM IIEL II H9B HH RKRKNNKANAKKKKKNNAKKKQHQARNNSQANQQNQQQHNQNKNHHKEQDQGQNHDNQNNKQNDRQKNQKKKNQQERREQQEQENENNNNREDEDQTRERKREAEEVRVVQEEEEEEEEEKEEEEEVEAEEETQFTEEQESKEQVEEEAVTTIEEDETTLENQESEEEIQKAERVKAIEQSAEQEEEKIRSAEKQAEMRAQLTKEQEAEFKEAVQLANEAAQQS ISESISLQERQTKAKNAQALEAAQISHEITEAALKDAQIEQVQAREQKETKIAQVVLADKMEDA QE Y FATA QQQL KQ H9 HH QQQQSAQAAQSQSQQSSMQVGQNRVQNTSRGVRQVRRVRGQVQRNARVRERQRSLVSRVSQRSARRRLRVRRLRRVRQRRRRRRRRRRISRRVRRRARRQQRRRNRRRQLRRRNNNRRRRRRRRNRRNRRNRQRRLRRRNRSRNRRNRRERRRRNIRQQRNRRNQRRRKRNQRRQRHRNRVQSRRNHQRQEQNIRRRQRQRKRKNRR RRNKRRRTNVRQQQRR QMRRKKRRRRQRARQARRQRQQRQKGRSKKNRKKKGQRKRRRRYERKKIRKRKRELLENSKNRR YN A ARQQ QKKR QE H9 HH IIIIIVIVVMIIVIILILILLITLLITLVLLLLILLILLLLLILVVLLLLLLLVLIVLLVILVILLLLLLLLLLLIVILLLLLLLLLLLIVLILLLLLLIILLLLTLLLLLLLLLLLSLTLLATLALLATLLLLLLTTLLLLTLLALAALLLLLLISLLLLLLLVAATLLILALLYILLALLAVTLYILITLLLVLTLLLLTLLLLT AALALLLLLLTLLLLT LLTTLLTATTLLLLLLLLLTSLVLTILALLLLTTTKLLTALVSLTTTATLTLALLLLLIIS LV LL L LLLL LLAL LL H9BB HH EAQEQKKKQTEQQTKEENSNESENNMQQENEENTQNEREENQAHEENKNNNKNQEKRNQQEGQKNGNKNRNNETHNTQKHNKNRGKKGQEMKNKKKTNKQEDKKTKKDRENKRTTTKQKQEKKKDKREKKQKKNREKKRTKIQEQKNQKARGRKNRERRRNKENRKQQRHEKKNKSQKTKKTEGQHTERQAKNSGTQQNKRNRETEQ KEENQRKKTEQKTRNE QQQERRQEKERRKSQSKATERKQRNREEKRNQEDETTRKQEKKAEEEEKQEKENAENSSEE NR QT E DDKD NNQR DT H9 HH EEEEQQEQQQQEQEEQQQEQQEQYQQQQQYQQYEQYQQQQQQQYQLYQYQYNYQQQQYQQEYQQYYYQYEYYQQYYQEYYYYYYYYNYQQQHQYNYEYHEEYYENYEYENYNYTTNRYRYYRYYKYEAYYKREYESYYYTENYTEYKSYMEYERKKYEEEKEYNEFYYEYYEYYEERETYNEYYYNNEEELEREYEYEYEEYEVNYH YYSFEEYQR YEEEYY ENYYEEYYYYEESEEEEYEYYENEYDYYEERERYYTENYSYEYAYYYYLEYERYMEEEQEL VD TN Q NEEE EELS EE H9 HH AAAAAAAAAAAAASAAAAAAGAASAAAAASGASASSAAAGASASGASASASASAAAASSAASAASSSSSASSAASAAAASSASASAAASAAAAAAAASAAASAAAAASAASAAAAAAAAAAAAAAAAAAAAAASAAAAAAAAAAAAAASAAAAAAAAAAAAAAAAAAAASSAASAADAAAAAASAAAAAAAAAASAAASAAAASAAA AAAAAAAAS AAAASSAAAASAASAASAADAAAAAASAAAAAEAAAASAAAAAASAAAAAASSAAAAAAASAAAASAS AA AA N ASTA AAAA AA H9BBBHH LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLILLVLLLLLLLLLLLLILVLLLLLLLLILLILSLIYLLLLLLSYLLLLLLLILLMLLLLLISLLLILILLVSVLMLLAMLILLLLLVLLLLLLLMYLMNQLLIYKLLLLYYALLMLLLLMLMLLLLLLYLLLLLLLLLLNLLLLLLLLLLLLSLVL ALLLLLLLR LLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLLLLYDLLLLALYELLYYLLYLLLNYKALLY YL YL I IIMI IILL II H9B HH RKQRKKKKKKKRKKRKKIKLKKKELAKRKEKKDKKAKVKKKKSETQQKELDAEKKKKEKKRDKREEEKQKEEKAETAQSEDSESSSSSKKASKSSEKESQRADQNGQAKQDSSDDETDDNSDQENGRHQDQTADNKSDQDRENDQDEKNKQSQAESTKAKEQSKADSNLESRDEKLTADDQRRRNNSRTQSRDVRVNSERKDANDST AENEIKEAS ALKKQREKQNRVARQVRKRIINKLSKRQVAKDSQRSRDSQKQEQADKLKDRRRQQSRQAKQKAHKEIK QHKND K SKRI SAND QS H9 HH YFYYIVYVIVIYIYYIIVYIIFIVVVIIVVIVINIVVVIILVVIIAVIVVIAVIIVIIVIYVIIVVVVVVVVVIIIIYIVIIVIIIIIVIIIIIIIVVIYYLMVIIVVVIIIIIIIIIIIIIIIIIITIIIIIIVIIIIIVIIMVITIIIVLVITVIVIITIIILIIIVIIVIVVTTIIILVMIIIIYVYIVTIIIIVVIIIVIIII IIIIVVIAT IVIVVIRIIIIVVIIIIVIIVIVIIVIIVIIMIIMIVTVIIIAVIMIIIIVIIIIVIIIIVVIIIIIV IIIVI I TVII IIIV II H9B HH AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAAAAAAAAASAAAAAAAATAAA AAAAAAAAA AASAASAAAASAASAASAAAASAAAAAAAAAAPAAAAAASAAMAAAAAAAASSAATAAAAAAAAAAAA AAT A A AAAT AAAA AA H9BBBHH DQNDQEESQQQEEQMEEKEEQQQNQKEEQNAENEENSQSALEKTRRKENQNQNQSQQNEQDNQENNNENTNNQRNKRNNNNENDDNNDQERNDDNNENNNDQNEKREQDKNHDKKKKKKEEKKLKIRKKRKKKNKQEKRKEREKEKQKLKEREKQEQDKEQEKQKKEEENNRLNGQEDKKNHAKEKQDENKRKKKREENREREKKKK KKKRDKNQQ EKKENRKQMERQNRKKQEEQDQEEKQQKRKEK QVLSKENESQLQKKKQEPQRSTKNSQNNKKEEKNL KQN K RRQQ EEEQ AE H9 HH EEQEQKQQQQQQQKQKQAAQQAQAQEQTAAQKAAKAQQQQTKEAQQAAAQAKAQQEQAKQEAQAAAAKAAAAKQADQQSAASAAASSAKQQSAVSAAASQEAAAKAAAANASASSKAAAAAASAKAALSANAAASDAAASAEAKAAKAAAAAAAKKASSAKSAEAAAAAAASAAAKQESAQSAAAEKEAQASRAASAAASASADKAA AAESASATR ASSSAANSKAAAKAAAAIAKKAASAAVASAAS AASAQAAAQAASSAAAAAAAHEAAQSA AKKSAEA DAKT Q AQLK SSEE ES H8 HH AAAAQQSQQSQAQSAHHSASQAQAASQQNAQQAAQAQSQQQQAAQQASASAQAQQSQAQQAAHAAAAQAAAAQQASQAAAAAAAAAAAQHQATAAATAAAAAAIAAVAVTAAAAAAAAAAAAAAAAIAAAAALAITAAAALIAALAAAAAVALAAAALSLALAASAAAIAAIAALAAIAAMIAAAAAAVAAIAIAVAVAIIAIAAAA AAAAVIAAA AIIIAAQIMAAIVAAAAIISVITLAVAAVAIA AAVIAIAASAVVAAAAAAAASASIAVA ALVIAIA LIIA A LLAL LLSL LL H2B H KNQKGGNGGNNGGNNNNKNGGKNGNKNGNGGGGKGGGNGGGGEGGGGNGNGGGGGNGGGGKGGKGGGGGKGGGGGNGQGGGGGGGGGGGNGGSGGGDGGQKGGGGGGGGQGGGGGGGEGDGGGGGGGGGGGGNGNQSGGGKKDGGGGGGGGGGGGNGGGKGKGGGGDDGGGGGGKGGGGSNGNGDGGKGQGGDGGGDGGGGKGGGGN GNGGGGGNG AGGGGGRGDDGGGGKGGGGDGGNKGGGKGNGDAGNGGGGQDNNGGDGGGSAGGGNNGEGQ GDGGAGG KSNL N GKRG GGGN GS 1 IVVILIVIIIIVIVVIIIIIIVIIIVIIIIIIIIIIIIIIIIVIIIIVIIIIILIVFIIFIIFIIIIIIIIIIIIIIVVIIVIVVVIVIIIINIIVTIIV IIVIVVILLIIVIIIIVVILIVVIVLIVVIILILLIVIILLIILVVVVVILLVIIVLLIILLILVIILIVLVILIIMIVILVVIIIILVVLILVLIIILLVLQILV VVIVYLVII ILLLIILLIIILLIVVLLLLVLTILILLLILVIIVLLILLLL ILVVLVVSVILIFLLLI VFIQVLQ LLIV I II L IIII II 6B TTITESTNDKTINTTSSKTTSVHKKNDKSKTSKTRKKKNTDRHANRTQKTKSKERDEKHETKEEKKKSKQKKSVKNTTKKKKKKKKKKSSSKAKKKKKKT NKESDESENKEKKKTTNRKKEDERDEKDEKTVKDNEKDKEKKKETKEESDSERKKTEEEKEQKETKKDKNEEKEKIDKNQETDKKKTETSEKNDVKVKETNETKQN DTKTDEKMK TEETKEKEQKDEDDNDDKEDQEKDYKENENSTSSIREKERKV RKIDQSNVDDVVSEVER SRNENVEAEEKE K EK N RRET VR 7 QSKQRRKRRLRKRKKRRSSKSTKKDAHRRKRRKTRKESERRRSKHHRAKKKRKQEKQKRQQKQKKKRQKERRRQRKQKKKKKKKRKKRRRQKKKKKNKKK KKKNKKKKIKKKDDNRKKHKKRKRKKDRHDRKKKVQQADNEQEKQETKAAQRKEEKRNNENKDKQQQRRKKKKESDNESQKSVQDSQKKAKDKVKQENKTKNQDRA KKEQSKKED QKKTKTGNQQSRSSTKKTKNAK GKDAAKETKERSKKDNKKD DKKTKTAPKTENNNDKR AKKRKNKKTGKK N AE K TTSE KK 7 PPPPANPNAPSPAPPSSPPPSPSPTPSPNPNNPPNPNTKSSNPPNNPLPPPSPANLSPNAPPASPPPKPPPPNPPLPPPPPPPPPPPPNSPPLPPPVPPP PPPNPPPPNPPPYYNPPPPPPPPLPPYPPNPPPPNPPPYPNPYPPYPPPPPPPYLPPPPYPPYSPPPPPPPPPPNYPYPTPPPPYEPTPPPYPPPPP PPPPPNPP PPYPPPPPY PPPPPPGPSPPPPPPPPPPSPP PPPPPPPPPKPPPPYPPPY PPPPPPPPPPYYPPYPP PPPPPPPPT SN F PP P PPPP PP 6 QQQQTQQQKQEQQQQEAARQRQVVLQMQVVQQVQQVREQMRQQVQAVQVAVRVKRQRVQKQVKQVVVQVKVVQKVQKQVVVTVVLVILKAKINVIIAVIQ MIPAIPLPEV VSSNIIIVVII NIPIIIIIPVPELIVSPKVPLIPLILQVLIANLPVPPPAPIIVVPVLPVVPNRPNVKPILVPVQPQLPPVLPVP PTLPINAL IQPIQPIVY LVPTVVEPKVVPPVVVVVPPQK PVQVVPVTLQVIPPPQIIQ QVLLILIQLVQQIPQPV LAAFLLLLMLVR V TL V TTL VV 6 IMIITTVTTVTITLIATVIVTITYVITTTYRMYITYAVTATTVYTAYLYVYTYSSVTYTTIYTLYYYTYVYYSNYVHVSYYSYYYSYYVTDSLYYSVYSV YYLI LYMIY YKKIA V YA I LV YALYII YKLI LI LL EVFIVSL IVSLLILVR IYEILYLVSVV LI E LMIVIEILI I A IIAIYISQ IL VISGA IIVYEIII EIVE IIIVI LNM EV I SY IILV AT MSALNP EASELTI EAFYEKLNEALA T TS S STN MI 6 QPQQDDQDDQNQNQQEDQQQDQDSQQDTSSQTSQDSPQETDDRSSESSSSSDSNGNQSNNQSQQSSSSSQSSSESNDQNSSSSSSNSSDDESNSSSKSSQ GGIS IGIKS SSSSR S SS TS IT NRVSDK SSIN SI SS NTMISNS IFFSIGSFT ISNE SIVSVS NN R SLQIQNESI I I ENDIDSNS NS TISQN SENSNKES NGIN NISKI IDT NQ N NS IQSD EN TTESNI NNDNINE NSDSNTIARQSK Q PAQA PPN RR 6 QQQQTTQTTQVQIQQVVQQQTQTNQQADVNAANQTNVQATVTQNKTNQNQNVNMTQTNITQNTQNNNINMNNAANQAQGNNGNSNGSNVVAEQSSEENEQ NSGVPGNSQN NLLDD D SE QD DVQ NDENRQ RLEV DT D Q AKTDIA NSEDGDDTN SNFV NSFKTI PL I DQQSQ VES S S VSVSPDAL DDQPSETS QVSN QVQ IS Q SKGAY EVTQLV S NNQTIET LV STM EM N LFVN I SKSYEHIPT N S QGNN SSYT TT 7 TAGTPPTPPVPTPTTPPATSPTPGATTTPGTPGTPGGAGAAPTGPPGAGAGPGPAAPGPPTGPAGGGAGSGGPSGAPTGGGGGGGGGGPPPGVGGGVGGT GGPPTSGGPGGGSSSS S GS IS GIT IAGGSL GIGS SG S T GGGSAM DGGSGISGS GGSSAGGEGAP AS SITGT SSG A G SS GGSTG GSTGGGPA PSSG PSP VG T SGISS GVANGS S EGTGASA GN AH FG P NG G S INNNTTPIP I I EPET GAFD EE 7 QQDQSEQEEDAQEQQAEEQEEQEQEEPEDQQDQQDQEEEQEDEQDAQEQEQEQEQDEQDEQQEEQQQDQEQQDLQD EAQQAQSTASTDA AESSANQAE ATQEGQAQSQISGGKVQAQAVQGKQAEGQSVQQAPQQQGQGQKGQKGGYKDGAAQQQGQKQSKDSQQGQYASQQIDQQQSSQ QKDQQQYAPKEEQA AA AVKSE QQKNKAASS QAAAQLEASQLGQLQNAAATRK ASQLDAQAAYQNSGPQENP QN GENQEELKQ E AQ YGQDQQKQER T P TADE MMEW VV 7 DEDDEQDQQQDDQDDDEFDGQDEATNDQEADEADQATSNENQNAANAYATAEAQ FQAEQDAQYIASEADSAEPAF DMAAMASAIVAQD MSQVQGIMD TVVNNITVIALANNLANINAATNLSALNTVASAENNMSNVENLNTLNDNTANIAVNMNTLMALNNNNNA GNISNNLFNEETDNLLDVDDGLTRQNT GANEALAQ TQLSTAQAN NAGAANNDENNNVNNNNANETM SEPQ ANADSGNASLMN N VFNNSVNARNESNILGN NNVVNHNSAL Q SMDT ATKE NN 7 VVIVLLVLLVLVLVVLLQVVLVLVLVLLLVLIVVLVLLLVLLVVLLVLVMVLVLLLLVLLVVLLMVVLVLVVILVL VIVVIVIIIVILL ILIVILMIV FIDIEDFMIVIIVVAIMILIIGDAGVSEGAIVVMILSMIDILAINAADVSFMILSFMMEADSSM LLLV MDMMSAQALILNSLSNVVVSMSVIMLL MVLVLAD SLSSSMINA LMMVVVIMILVMMALNLVVSSV MNPD MLVMAIDMVSSL IINALVLDMV GMNML VLLV IDL L L L LNLV EQGA NS 7B TTTTPPNPPSPTPTTPPSTSPTPKSSPPPKPPKTPKPSAPPPSKPPKSKSKPKPSSPKPPTKPSKKQPKSQQPPKSSTKKKKKSKKSKPPPKSSSKSKKT KNQSNQKNPKKSSSDNGSGLNNKDNDDKNSNKKSPGNNSQPGDASDRKQSHANSSGSDRDQSDA GGDKGSNKNNQRLGSSSQGDNTDTRNDDDNGQ GDTSSDN NFDDSSKNN GGNDKRSGSGRDDRGQNDDDSS DNRQKGNDNSKKDDDDNS DQNRDDGPNRG DDPSN QDTS IIP S D E SIFH SSSS QR 7 QQQQDDQDDQDQDQQDDEQDAQDDEQDDDDDDDQDDDEDDQDQDVPDDDEDSDDDDDDEDQDDDDDDDDDDDDDDDDQDDDDDDDDNDDDDDDDNDDDDQ DDQDEQDGDDDDGGGDSDEDDDEGDGSEDDDQDGDEGDGQSEGGSGDEDDDGDDRDGGQSQNGGEEEGDDGEDGASQGDDADEEGPQGQEGNGSGEG GSGA GDD DNSKDGDNT EGGDDDDGDEDGGDDEGSGTDP GSQGDGENNHDEGGNGKQ GDEDSDDVSDE NGNGK DEEEDDFQ D N S GQDN PE Q QE 7 DDDDSSDSSDSDSEDSSDDDAESDDDSSSDSSDESDSDSASSDDSSDDDDDSDSNDSDSSDDSDDDDSDDDDSSDDSDDDDDDDDDDDSSSDDDDDDDDD DDSSLSDSEDDDSSTDNDQDDKITNEKLKSDSDDDQSDTGEQTQNSFRRNDQDSDKNGESLNASIQQQDRAIDSESEDKDGRVQTEDSDRAPQQSQD SKVD TNL HITINADSV QASRDGEQDQGDNGKIQKEKGG DSDSISEKDSDRDQPSKIE SDIFSDKAGGLDFEEEE RSEPRQDT E P A DGSS RISG IT 6 TTTTEKTKESESDTSEETTTDTDPTTEDEPEKPTKPDTDEEKTPEEPTPTPQPEDTEPKETPETPPPKPSPPKEPTATPPPPPPPPPPEEAPTPPPMPPT SPLYFLDLAPPPYYYPEPEPPEFYELRFEYPLPMAEKPYLSEYPEYYFLLPLPYMELLLYSYYDFEELPFLFPLQYLYEMMEFEYLTLTFLYTELEL LMFMLYYF EDYFLLPAH ELLMPFPLLEFLLFEFEMMYEP LYTLFLKMETPFLLYMEFE RPFYYLESEFFLLLELE LLPPFMTN V Y P PPAA PPFE PP 4B MLLMLMLMLMMMLMMLMLLLLMMDLMMLLDLMEMMDRLLLMMLDMLDLDLDLDLLLLDMLMDLLDDDLDLDDMWDFLLDDDDDDDDDDMLLDLDDDLDDL DDMLGMDMLLDDLLLDLDIDDLGLLTLSLLDTDTLILDLMLILVLLASLMDIDLLLMAMLMPLAGIIIDPTDDMLKMLLLDRNILLMMMSTLLITLM TDPDPLPP LMLDMTDLQ ITMDDNLTLLNTMAIAFDTRML MPLPSTLDLQDHAILLINL LDQAPMLYINQLPTLTI LLLLPI L M L E LLLL LLNL LL 1B H FFFFFFFFFFFLFFFFFFFFFFFYFFFFFYFFFFFYFFFFFFFFFFFYYFFFYFFYFFFFFYFYFYFFYFYFFFFYFFYYFYYFFYFFFFFYYFFYFFYF FFYFIYFYFFYFFFFYFYFYYFIFFYFIFFYYFYFFFFFYFFFYFFIIIYFYYFFFYYYFYIFYIFFYFIYIFYYFYFFFYFIFFYFYFIYFYFYFY YYIYVFII F FIYYYFY FYYYYILYFFIYYIFIFYYFYY YIYIIYFYF FIYYFFFIF YYIIIYFSFIIFIYFYF IYYYIY NYYFY Y YYYY YYIY YY H6B HH LLLLLLLMLMMLMLLTLLLVMLLSVLLLMSMMSLMSLVLMLMLSLLSLSVSLSLMLLSMLLSMLASSLSLSSLLSLLLSSSSSTSSLSLLLSLTLSMASL STMMEMSMMLSTMMMAEAASASEMAMMDDMAMSMMAESMMLAMMDMEDSMPMAMFAMMMMMSMMDAAMSMMNAMLLMMAMMHQAMLLMLSMIMNMAM MQQMTISQ S MEMMSMM AMMQSEMMMAEMMESDNQIMMK MSADNMSQELMGMMILSEN AAQESGAANENNEMNMA SIMMTRSSMLIL T FYPL FFAL FF H7 HH LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLQLLQLLLLLLMLLMLLLQLLMMMLLLL LIRLLRLRMSLMLLLLLLILLLLLLRLLLLLRLRMILLLRLILRLLLLLRLRLLLLRRRLRMLRLIIRLLRLLRQLRLLLRLLILQLRLLRLRLRIR RRLRLLLM L LLRRMLL IRRRLWMRLIWRRWLLLRRLRR RLRLMRIRLQLLRRLNLIL RLLLLRLMLWLLLRLRI LRYMLLLAQQIL K MLPL MMLK MM H8B HH GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG GGGGGGGGGVGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG GGGGGAGG GGGGGGGGG GGGGGGEGGGGGGGGGGGGGGG GGGGGGGGGAGGGGGGGGG GGGGGGGGGGGGGGGGG GGGGGGGSGGDG G GGNG GGGG GG H7BBBHH SSSSRKSKRSRSKTSRRSTSRSVASSTKRAEVASAAQSQQHASATVATASATARETRATRSARSSAAVAAAAVSASSSAAASASSSTSTRVSSAAAESAS VSTESSTSVQASEEESSTSGTASESAEASESTASASEAEAESEATESSSAETTETSSSAETYESTSSTAKTFSSEESEAVSVASEESSSTTESASSS SSTSYEYA SSEAASSTE SSSSAAVSVSATTSSSSSTEAS AYSAASSSTVSASTETATE SSTSYSARSSETSSEAA SYSRVSYQTSNR Y YYPS TTAT TT H9B HH DEEDPPEPPEPDPEDPPDEDPEPDDSPPPDPPDEPDQDPPPPADPPDSDEDPDAPDPDPADDADDDDPDPDDPADDA DDDDDDDDDDSPSDDDDDSDDE DDKKKRNKPTDDKKKEQERDEKKKKKKKKKEEDKPRKRQKSRKKKKKKKKKKEKKDKKKKKDKKKRRKDDKKDKEKKKKPKKKRKEDKEKKKDKDRR KKEKEKDS QLTKKKDKN RKKKDKARPRRKKRAKRLKKKK KDKRNKKKEDQNEKKKDDK KEEKDKKPKRKKKKKKD KEKKDKKSIRKE E KQAD EEKR DE H9 HH AAAALMGMMAMATAAMMAAAMAMGAAMMMGMLGALGMAVMLLAGVMGSGAGMGVAAMGLMAGMAGGGLGAGGLQGAW AGGAGAGAVGLMGAAAVAAGAA ATAYGAGAAVAAYYYAAAAAAGGYGAYGGSAAGAAAGGYAAANAAYAGGAGAAYAAAAAYALYVAAAAGGAGGAVLAYAIAAGAYIAAAGAYAGAAA AAGALYAA GAYAAAAYF AAAAGAVATAAAAAAAGAAIAA AGSAAAAAASGAAAYAAGA SAAAAAAAGAAAAAVAA GVAAGSGSAAGN I TVLL AAAI TA H9B HH LLLLLLLLLLLLLLLLLLLLLLLILLLLLILLILLILLLLLLLILLILILILILLLLILLLLLLILILLLIILLILL LLILILLLLLLLLLLLLLLILL LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLIILLLLLLIILLLLLLLLILLLLLLLLLLLLLLLLLLILLLIILLLLILLLLLLLLLLLLILLLLL LLLLVLLI LILIVILLL LLLLLLFLLLLLLLILLLLLIL LLLLLLLLLILLILIIILL LLLLLLIVLLLLLLLLI LLLLLLIQLLML L LLLL LLLL LL H9BB HH KSEKQQSEQSQKQGNQQQQKQQKASEQQQARQQKQAQSQRQQEAMQEQASGQAQRNQSQQKAQRAAAQANASEQSKQ QAEQANKQNKQQQQRNNSKAQE RSRQERRRENKNQQQESEKKEDEQEESDEQESEENKEAQRSKQKEKQQERSKEKDKKERKRNKEENKKSAEKAMESKQKNEKAKQSKKEAESQAEKN EAKKNQNE DEKEKESQS KEEIAATRRKATKAEAAAQNRK RNQAEEQAASSKRETSSKK QATQDLKMAAKKSAKQS EENLSNEDEQSA A EERV TARS KS H9 HH SSSSAASAASASAAAAAYSAASAQSSAAAQAARSAQAAGAAASKAARAQSRAQAAAARGASEASTEESQSEEAARAA RQRRQRRRSRAAARSRSSTTRS QKAAAAQGAARRAATEAKAQKAAAAAAAAAEARAAAASAAAAAAAAEAEARAKAAAEAAAARAAAAAARKAATAAAAAATAEEAAASASEAAAEAAA AAEASARA AAAAAASAA ASSAQEAAAAEAAEAAEAAAAA ARAEAAAAESREAAAAEEA AKEEKAAQEEAAEAAAE EAASKAESKA A A AAAA AAAA AA H9 HH MMMMRRMRRMRMRMMRRTMMRMRKIMKRRKRQKMQKQTQRRQMKRRKMKMKRKRQMRKQRMKRMKKKQKLKKQSKIR KKKKKKKKKKQRRKMKKKLKKM KKEQKEKELNKKQQQKKKKKKKKQKEEKKQKEKELKKKQELKQEKQKKKEKEKQQKEEEQEQQEKKKEKKEKKELEEQKMEKKKQLMEMREQEKEKE EEQEQQQK KKQKEEKQE KEEE KLEIKKEEKKKKEEEEE EQEKKEKEKKKKEEQEKKK EKKKQEKMKKKKKEKEK KEEEKEEATQ Q E EEEE EEEE EE H9B HH IIIILLVLLVLVLVVLLIIILILLIILLLLLILILLLILLLLILLLLILILLLLLVLLILILLILLLLLLLLILLAL LLLLLLLLLLILLLVLLLILLI LLILVILILWLLVVLLILVLLIILVILVVLLILLIIVLVIIVLIVIIVLLLILIIVILIIILVLVVVILLIILIVLLVIIIVVVILIIILIIILIVM IVSILLLL IIIILILLI VIII LFIIVLIILIVLVILLI ILLLVIVISLLVIIILLSI LLSILIIRLLIIYIVIV LIIVLLILLLII R RKIR RRKI RR H9B HH QKKQEEQEEEEEEAEEEDQQEDEQKKKEEETEEDEQDQDEDEKQAEEAQKEEQEETEEEEQKEDNKREAAKREEENE QEEQQEEQEEEEDKQEEANNQK DEKDKEDEKKQEDNDGKADRLKKDKTEKQDAKEVQDKNNKKDDEKDKKSTAETDDELKSDREEKKDDEEAANNQDKNDTEEEKDDEQQKAASRNADE ANNHKDEN QADKAEATN DAQS KEEEDKEEKNERSKQAE NEEKKADVKQQENEDANLK AAQKEGADRIDVKAKKN SEGEGNKDKNNE F EDKT DDNK AD H9 HH NNHNNTNTNNSHGNHSNNRNAHLINNLSNIATINTITNTAATNISLININITINDNNITSNINNIIITINIITMINM IIIIIIIIIITIMINIIINIIH IIAIAAIAQLVITTIIAIAVIAAIANTAAVIAINQAAIITNAINAVIVLVINIVNAVASVAIVNAAANIINAITVALTAHNVIAVVNAHLNASINAT NAINEIIV AAVAVTIAS ANNA VLNHAVNAVASIANQVN NIVIVTAAVIIVNNSLVIV VILIINASIVVVVNVNV LAAQIAQ YADA V TVNV AAVS AA H9B HH EEEELLELLELELEELLEEHLELEEELLLELLEELELELLLLEELLEEEEELELLELELLEELEKEELEEEELLEEL EEEEEEETEELCLEEEETEKEE EELALLELEKEELLALLLLEELLALLWLLALLELELLELLDLALLALLLLYLEALLLLLALELLLLLLELLLKLTTLLLELLLLLAELELLILLLLL LLLLLAEL LLLLLLTWL LLLL ELLELLLLLLLLLLLLL LELLLLLLLEELMLILLLL LILLELLLLLLLLLLLL LLILLLLPLLDV L LLLL LLIL LL H8B HH AAAAQEAEQAQAQAAQQKAAQSQKGSQQRKRKKAQKQSRRQESKKQKNKAKEKQQNLKEQASLNKSKMRSQQKKKKK IRKVKKKEKKQKKIAKKESKIA QKEKEEKERKDKKKKKQQKKQEDKEEAEEMKEKEKREKKQGKKRESKEKEREQNVSEEENRRNEEKKEKKEEKEQKETEKRRNKTKAEAKEKEIKKQ EEKEKKKK EKKQRQEET KEQE LQQNKKKEKKEKEEQQK EQRKEEKEIIKRAEEQKHK KEIEKNEKKKKKSQKEK KKKKKKKAEAVQK I KKSR AASE QA H5 HH TTTTAATAATATASTAASTTATANTSAASSAATSANATAAAASTAASTNSSANAASASAATSSTSASASTSSAATSA TSATNSSTSSA AKTSSTSSKT TSANSASSDQTSNNNNSNNSNSSNSRRSSANSATETNSNDGSTKSESSSQTSNENKAGAETSQNKSSSTSSNSANDNNSNSSESQNTSTSAQSKSSA SSSTNNSS SSNSTSTNE SATS KDRNSNTNDSSEAEQSA SSNEEASSKTNSMAQASNS NNKSSDDANESSAQSES SSNNSANMAQNQN Q GKAK ANSS SS H1 H RRRRSSRTSRVRSRRVVRRSSRSKRRSTAKVTDRTDSRIVATRDNGDKDRTAKSSKSVTSRLSKDLKTDRIDTGDKN DDTDKDDDDDT NDKDDDWDDR DDRSNRDRWSDDTANRNRDDRNNTNRSNNQRRTRWDNDARRDKSNKNNIRDRRKKNRRRKSDERNDDRDKRNKRTARNNLRNVDKSRRRLRNRDSDR RRDRNTDD NNNENRDNS NRRR NTRLDNRRNNNIRRSRR RDDNQRNRDDNNRRSRDDD RDDNDRNDDNDIVRDRD IRRRIREAQRLQT Q KRRN RRDA RR 6 PPPPGGPGGPGPGPPGGPPPGPGDPPGGGDGGVPGVGPGGGGPLGGVPVPDGDGGPGTGGPKGPVKDGVPVFGGVPG PVDPDLLSLLG GPPLLPPVPP PPDPLDLDPLPLPPHDLDLPDLLKLDPLLKDDDDPLLLPDPLEDLGLLDDLDDGPLDDDGDLANLLLDVPNLDDPPDKLPDLPLGPPDPDDDDPDLD PDLNSPLP LLNLDDPPP LDDD LRDPLPDEPLLKDKEDD DLDPLDLDLIILDGNDLLL DLLLLDLLPLLTDKLDL DKDSEELLKDPNP L LDDD DDLQ RD 8 LLLLPPLPPLPLPLLPPLLLPLPILLPPPVPPALPTPLPPPPLAPPSLSLVPVPPLPDPPLDPLSDVPTLDTPPALP TSVTVAATAAP PALTATLSTL SVDVSDTDLTTALLVLTISLLSSISDISSILDVDLSSTLDLSIDSIASLDRDIVVSDDDVDTIDSSSDAEDSVDIIDVALDGESVVLDLIDIDEDSE DDSDYVTS NDISDDTTI SEDD ELDLTEDDDSSSDLPDD ATTEEESDSAASDDIDSAS ASSTTTAPEESDDDSDS LDSIIKILKDMIV A HDDD DDAP SD 8 AVVVASLSGTDITTVSAPIPSVGAPVSADASDEVDEAPESANVDQQETEPAETDDDSVDGVVSVEVTDVAVEDTEEV QEAKTSQMSQN VSVTSTYELV ELPVVPEPQ KSVVVAVAITAVVVVPIVVIAPAPTVVEVPDVVPVVVVVPQPAVTVPPSVPSVPVVVPEAPVSPIIPVVKPVLVIIVPVEPIPLPVP PAFPEVTV VVIVPATIV VPPA LPPNVLPPIVVQAPSPA PTPFIPVALLEVPPIPILI PLIVTAVAVLVVIPIPI VPMEENLVNPAIV N DAAA FFIN DF 8 FFFFYFFFYFFLYFFYFLFLYFYELFFHYEYYLFYLYLFYYYFIYYLFLLEFEYYYYIYYFLYFLLEFLLLLHFIYF ILEIEILIILY FILVIVLLIF LIFYIFLFF TIYYYLILFTLIIYIFYIIFLFEFFFILYFLFYFVYLIYFLFLYMIFFFYFVYFVFFFIYFIEFYYFYIFFILFYYFFFYFYFLFFF FFFFMYVL IIYIFFVYY FFFF LFFLFLFFLIIIFFYFF FVFLLFFFFILIYFYFLFLFFSFLIFIVLLLFFFLFL YYFGYLIYFF YY Y GFFF IIFL EM 7B SSSSDDADDSDSDGSDDSSTDSDLSSDDDLDDNPDNDSDDDDPNDDNDNDLDLDDSENSESNGDSNLDNDNNDDDDD DNLDLNNDNND DDDNNSSSDS DDIPEINIS NNPPPIELESSEEPEIPEEPIILIDEEKPIGESIEPEEQISTMPPEIIIPINPIEEEIDMIELIPPIPENIENEPPSISKIPINIEI IIEIFPNE EAPEIISPP DIVI NDISENIINEENIIPMT ININEIEIENNEIIPIDEDDVNEENFEDNNEKDIDLD QIIGMDSGSL PP D LTII EENS EE 5 PDPPLISILDIDLAPVLDDVLPLNDEILLNISGGVALEIITLDGISANANNKNIIKLGILPALDGANSARAATAGKA AANANTSAVSE AADATSDGAP APPTPPAPD FTLLTSPNPAEPPVPNPPPPSPNKPPPPLPEPPSPPPPPAVDSPVPPLGPPAPPPPPKGPQPSPAFPVPAAPPPPDPPSPQPQPSPD SSPGLAAP PPPPVDSAV PRNS PAPNPPSPPPPQPKVAP PADPPNPAPNVPAGPGSPPVDSPPAPPAEPPPPPPVP PPEEPPKDNP AA S SGPP PPDP PP H2 HH AANAEDSDDQDNDGEDDYDDDADAYDDDDSDDDADDSNSDDDDDDDGVDSGDADTEAEDDASDYESADAEDDDDDKD DAGDAEGDTGS DDNDTESEDN ADANRAGAE DENNNERERDNRRDRKNRRREQGERRRENARRRRRRRRKEARERRRAGGRADRGRRRKDENRGASRGSRSKRERREATNENKNENRE GDSQNNDQ RRRREGDAR QGND ADGSRVRSARRDDSRDE EDGAKGRNKEDRNRKPNQSDGDKREAREGVSLEESSN KEGDEGRDRQ SN H NKKE RRK RR H7 HH YYYYYYYYYYYYYYYYYYYYYYYDYYYYYDYYLYYFYYYYYYYLYYLYFYEYDYYYYLYYYVYYLVDYIYFFYYLYY LIELDLLLLLY YLYLLLYLLY LLLYLLLLY MLYYYKLDLLLLLYLLYLLYKLELYLLLYLYLYLLYLLLLLLDYYLLLLYLLYLLLLLLILLELYYLFLYLLLLYYYLYLLYLLLLL LLLLDYLL LLYLLLLYY LLLL LYLYLLLLLLLLLLYLL LLLLILLLLILLLLYLIIIYLLLLLLLLLLLLILILL LIVILLLYYL YY A LLLL III II H9BB HH YYYYDDYDDYDFDYYDDYYYDYDFYYDDEFDDRYDQDYDDDDYRDDRYQFLEFDDYYRDDYQYYRQFDQYRRDERYA RQLLFLQRFQD ARYLLKYRRY KLRYLRKRY ALYYYLQLARQQLYQRFQQYLRLRFAQRYRFLYRQYQQQRQRLYYERRRYRLYRQLLRRMRQLRYYRYQFRQGAYFYRYPRYRGRAR RRTRFYLS QQYQRRKYH LRRR SFRYLSRRSQQSRRYRR RLRSQRARGLRQRRYREDSARLGLLRQLASAVHSSRG QRSYMSNSRT YY T RRRR AAT AA H9B HH QLQQQQQQQQQQQARQQQLQQQQQQKQQQQRQNQQNQTQRQQKNQRNENNRQQQQEQNQQQNQENNQQSEYNQPNEP NNRNQNDNNDQ PNSNNNSNNQ NNGSQGNTD NNNNSQQQVNNQQSQDEEQAQGRGDLQNNGYQQEQQQQSGEEQQEQTKAQNNQTQQQMNEEQRTREDTQDQQIIQQQTQKEQVKQIV ESQESINP QPQQGANRD QPES DEADQGEFDQQKTAQEK TNQDIPLTINNKQDQGEIQQASVQNEQDKGIEREGDQ SPQIEDNRDP QI A NETN EEL DE H9 HH TTTTNNTNNTNTNLTNNTSLNTNNTTNNNNNNRTNRNTNNNNILNNSTRANNNNNANRNNTRNTRRNNRTRRNRRLR RRNRNRSRRSN RRARRRNRRT SRLTILSLD RRIITNIILRRMITILIIVINLNITLIRILYSILIIIILLQLIIVLLLLILKVLISSLRLKINLLVLIIMRVILELTLTLKILIRLL KLILVTKL IIVVIRRYI SLRL LTLASLILLIILLLILL LKTLIRLLIRQVLLILIAMNASIIKLIRILMKIIKLI LILLLELMML AT M ILLL IIL II H9B HH KKRKKRKRRRRKRKRKRRKRRKRRRRKRRRRVQKIERLRRRIRQRREQERRIRKRQRQIKKQRQQERTEQEEIRQQQ LERQRKKLKKI QMKKKLRQLR QKQENQQQQ LKQEERDRQAKNNEAQKNDEKEREQQNKEQQKQQNDTNQEEQRDENQQQDQKTQNKKQQKQNRQQKEEDQQQRQLQKQRKQQQREQE EQKQKDKM NNSNEQLLD KQEQ RKQKKREERDDRQQEEE QKQRNQQQQKEQEETQKQQKQQHTKEDARRTQKKQQR QQLPKKNQKRKQD S REQQ QQS QQ H9 HH QQQQAARAAQAQAKQAAQQQAQAEQKAAVEAAYQAYAQAAAAKYAAYRYQQAEAARAYAAQYARYYEAYRHYAAYRA LYQLELLLLMA AFRLLYEYFQ LLERAEQEL LLAKRVAQGIIAARAARAAEMEQEVGAYKESLEGAYAALNDAQYRSENEYELANALLAYVEAQEYREKAEEALTLYQEQVEEVLASE EMINSRLA ASSANEYQR LEEM LTVALQTELSAMMVNNG EFALSEAMTFYAESQLNAIASQTALTAYLLIISTIMN VEYEVLLLAQLNR G EEAE SSS AS H9B HH TNNTMMNMMNMKMNTMMTKNMNMYSNMMMYMMYNMYMSMMMMNHILQAYSYMYMMAMHMMTYMAVYYMRARHMAYAV YRYYYYIYYIM VYAYYNTVYN YYQQKQYQW YYKQQYKYKNYKKQKREKKQHRYKQKKRQKLSQKKQQKKQGKYQMKLQRQKYQWKSSKHQKKYQEQRQKMAKQKKQTQNQKQKQEKE KRKKKQYK KKQKQRNNE SKQR QAKISQKQKKKRRREQE KLQQKKQRKIRKRKLERQTVQYQQYDKAQQTTERTRK KRRLSKKQNAQQQ N EREL EEQ KE H9B HH LLLLLLLLLLLLLLLLLLLLLLLLLLLLQLLLVLLLLYLLLLLVLLLLLLILLLLLMVLLLLMLVLLLLLLLLLVLL ILLILLIILIL LILLIILVIL IILLLLIEL MLLALIIILIILLLLYLLLLIYLLLLLLLYYQLYLILLMLVYILLLELYLQLLYLQQYVLLLVQIIYVLFMLLLEILQLMLIYLVLL LYLQLLLL LLLLMLMIL QVAY LLYLQLYLLLLLYYLLY LLLLLIVYLILLMREILILLMILLLYLLLLLLIKLFL MIILALLILRLML A LYLL LLL LL H9BB HH LLLLAALASLNLTLLANMFLNLSALLATAANSELAASMTTTALQTNSLALESANALTDANLSMLNTSSAIAASAELA EAEKADNKDSA ANLDDQQNKL EEAADAGKT EDLNSDEKSDDDDTDEETNKDKEASEDESAFFLDDEDEAESDKKTESDAKANEDDFFDEASEVLEDSSDDADSSLELRLASTSSSSS LNGSDFDD DMSTDAKDS FTAG SSSAFSNGSTKSNSQNN SDNSKTQNEETDAAAANNDARQDDDNDK NDNKQDDA ASDWDESNELETF L ENDQ AAN SA H9 HH DDDDTTDTTETDTDDTTADATDTQADTTSQTTQDTQTATTTTNQITLAQAQTQTSATQTTDKTAQKETEAEQTMQAM NEQSQKKNKKT MEAKKQAQED RKLKMLRLL RKNLKNMNQLDMMKMFQMMKNLQYLQMEELVDKFMQMMRFRFSQEQLFLQMKEFMDDFQRFMNLAERLLSFLSQEADLDRFQFSFQV FFLFVKKT MMEMFFQGL DFVF SLLSDSFFSLMNFFQFF WKLSLFQFLKMLFFLMLFTALQLMKMLT SAAMFSTI RYQNRLSQFMKEK L QLFK MMY LM H8 HH IIIILLILLVLILIILLIIVLILLVLLLLLLLLILLLVLLLLILLLLLLVLLLLLVLLLLILLILLLLLLLLLLLLL LLLLLLLLLLL LLVLLLLLLI LLYLLYLYL LLLLLLLLFLLLLLLYLLLLLYLYILLLLLLLLYLLLLLLLYLLLIYYYLYILYLLLYLLLLQLLLYLMIYLLLPLIFILLLLLYLL LYLYLLIL LLLLLYLLL LYYY LLFILLYLLILLYYLLL NILLLYVYLLLLYYALLLLLLLLLIYMI LLLLYLYL LLLILLILYLLLL I LYL LLL LL H6B HH KSEKNNQNDQNRHEANNSDNNENKSQNSAQNNKENKQKQSNNQTDLEKQSTNKNQTNLDDKQNEVEEAKNEESEATE KKTEKNRENRN EKTNNEQVKE SNETNESSS GNLHTNKSNRQNNTNAENNDNETKSNKEEENENKEEDAKNEKSEKERKTESTEKEEESAERALSEETNSNRGKELEKNEKREKKRND RRSKSNNN NEEEQREKA NRRH RSNNEKNKQNDKRKAAR SMKQNRERSDKDRKQNQKNASQSDNKAK KNNNQNKQ KEKSKAKKQEQVN K DKQ KEN E H2 HH NKNNVVSVVAVNAKDVVAKSVKVKATVVTKVVKKVKAATVVVTAAVKNKEKVKVAHVAFANQVNVQKVKNKKVNADS AKKKKRETTEV SSHAAQKVAS QNNKNSQSN KREVKSSEVNENNKNGPNNVGNKSSKNKKGSTTGNPSNSRKGEPKKGGKPTAPAYTTSAGTNVSPGGSKGSKATLANSSQTAKASVE AKKDSKAT NNPSKGKPP ENSK ASSSTAQGANGEMDAKK SAEAQELKQEQKDSKLRDNIEAKSANKS AKTDGHGR SSKLENSADRSKK K SSS NN N 3 LLLLGGLGGLGLGLLGGLLLGLGLLIGGSLGELLHLGLGGGVILGGVLLLAGLGGLGMGGLVGLAVVGLYLVGGMLG VLTVLLLVLLE GLILLIIALL VLELLKVLF VLKLLLMLGILLLLLLLLLLLMALFLLIKLLLLVILIFIVIFLLLLLLLLLLLLLLLLMILLVLLMVLLFLLLLVLLLLVLLLLLDV LLILILLI LLLLIL IL LLLL IFFFLVLVITLLLLLVI LLLILFLLILILLIFVEILALLIILILI ILLILLIE IILLVISLAIILL W VLL V 7B KKNKPPQPPEPKPKKPPKKKPHPSKEPPPSPPNNPSPAPPPPVNPPSKSRNPSPSKPNPPKKPNKKNANEDNPPNKP NNNNSEKNEKP PRKEEKKKKK HKKAEQHRR KEKEATKDKKTEEEEERDRRTSNEQSESVTTSKKKKKKSDREDKPKSESKKQKEKSSENRKK RLLSESKQKKSKQKSKSKKTKRVR KNYQKAQE ETKEDK LL SKKN KKEKSKSQKKVSKSKSV SKDKAKKNKNIKKSKEVNKPKDKKQKEA KETDVEDL SAEEEDNQKAKEA R EAK K 7 VIVVVTVTTVTLTVVTTSIATVTVSVVAEVVVVVTFRHKVVTVITVVIFSVAFTGVTVTSVVTIVVIKLEIITAVFA IVVVFILIILV AIIIILLVVV VILPILLVL IIVKPTIIKISIIPIAHIIITPVTLVIIELLAVVIAIVLVVIITEIIRPTLPVTIAASVIVI VNHVQILVIFAVNVIVLVELLILL IILVPEPR IVAVVV NE TIVI LLVAALKALIVPVVQIV VPPLVLVVLVVIISEPPLVKSTLIPIIP LFTVAVVP LYVTLLIVLLLTE H IVI L 8 TDDTLLDLLAVEPDDLLKDQLDLEKKLLPEVLSKLAVKLLLLKSLVKQETDLSLLELSLRTNLQGNKLANKKLLSEL NENDAPADPAL LNDPSGSGDD ADNQDSSND DPEKLKDDTDKDDSNEYDNKKENAKSDRKNDEEKDKDDENDKDKFNKGDKDVKGDEESSDDD NEDDKDTDNETKKTNDEDGDQDSN DDDNELAS DDKDND IQ DDSD ESANEGSLENDQESKST DVAEDDKDDDPNNNALKEDLAKDDVNNF GDDNADNQ DDDLKDPKPDSDL F NNI S 8 APDAVEPDDPDGDPNEDPEPDPTDPPNDDDDQDPQDDANDNQPDNEDADPDEDVDVVDQVADVVDDDQDLDDQADVA KEDKDNDKKDE AKMKKDDDKD DNFLSFDTE TNKVVENTKNENTLDPKTDDEVDPEPTNELEKKVTTTNGPAATTKDSTEIVVEESKKIDAPN SQNMDDEPDNKEEAPDGPKPNPQE PPKPNVVD TKQSPP KQ KPPP QEPHKQYSEPNEPPKPP STAEPPPSKNDNELKPIKDDEDNTIADS QNDEKDPI GK SDSKGNPDKV N GRK N 7 DSLDDEKKEDAATKIQPESDSSAVDDAEPVAEVDDVQDSAKEQVKKMDVEVDVNKEKVKADVKDVVIDVDIVDDVED ITVVVVVLVIN DVSVVLDVVL LIDEVDLDR IVVEELILWILVVDAGIVVILQVDQWVTSDSWVGIVVIIDPRIVVIEYSANISYIWWLVLSI EPIGSIDAIAWAPDELISLSAAWD SEDDVEIV VVVIDQ PV WSDG QSEDWQRELDIVDNADA DVTLISAEITLIDQLEEARQKIIVIEVL QSAMRHEE ID IIKILA ILE D DNT L 7 TSDTTTTTKSRENTNRRSTTKTKKSTKKNKANKTQKQTQASQNSNQTNSTKNKTLNSKTTTDSNDDENDGTESRKNR DDNDKNNDDNN RDNDDQKDND QDRSERKEH DNGKNDKDSEDDDNDGNEEKDRNHGAENAKNSTDQKDEANDDDKDRQEQKKDKSRSSNKALK RTQAKNNVQDSKETKDNLESELSD LRTTNDDQ EEKQNS TT SSQN SRNNSSEEPEKEQDNGD ANNPVVQHSTSQADELSKSNKWRDHDEN SSSENSKN AV DTLNTS KED T LQD E 4 VLVVFFIFFVFLFIVFFLILFIFLLIFFFLFFFIFLFAFFFFIFIFFLLTFFLFFLFFFFVFFLFFFFFLFFFFFLF FFFFLIFFIFF YFVVVFFFFI IIVVFVIVF FIGVVFFFVFFFFVFVSFFAFIFVFIFFVVFVGVFTFFFVIVFTIFVIVAVVVVFVVVFFVF VFAIVFLIFFIAFVVIFVTVFIVF VIAVIVIV FFAFVV GA IIFI FFVFVFALFFFFVVAVV VIFFFIVLLFFFFVTAFFFIFFFFLFLI FFFFVFIL FL WYIFAV IIV F FVF N E0B EE HHHHQQHQQHQHQHHQQYHYQHQEYHQQQEQQSHQEQFQQKQHEQQPQEYIREKQQQTPQHQQQMQSQQSTSQQTQH ETTKEVTQVTQ QQKVVVEMQH QVAQQAQAH TVSSKEQISTTQQKQKLQQQQATKDNQPSAQNQSQKHQRSQSTQKSAASDAPNTQNNETRAQ SEQATKSQDQNNQHAHRANSVENS ESKSEKQQ QANQSQ VQ NNSS QQSNSQKAHAESSVQAT ASKQQRQSQQPDRVDQKNSQKQEHDRNV QTVNSTST RK DRSMQQ INK N KA N E1 EE VAAVTTATTATSTVATTSAATATPSSTTTPPAPVTPTSTPTTAPTTVSPAPAPTTSAPTTVPTSPPPTPAPPATPST PPPPPPAPPST TPSPPPAPPA PPVATVPVA PPGGAPTPGPPTTSTVLTTAPVPVASTVGVSGSVSAATPVAVPTSAVVVTVTAVTGGVPPMT VSAVSSIVNSSAAVVAPMAVSVGV MVSVSTSP TSATVV AV GVVV SAVAGSAVSTPSVVSVV VAISTVGVSPVNVAALVAPTIPSAAMAP SPPVVPVL PV APASTL PTT F VV A E6B EE YYYYWYYYYYYYFYYYYFYFYYYFFYYYYFYYFYYFYFYYYYYFYYFYFFFYFWYYWFYWYFWYFFIYFYFFYYFYY FVFFFFYFFYY YFFFFFFFFY FFFYFFFFY FFYYYVFAFFVFFYFYYFFFVFFYIFFFYFYFFYFYFFFYFYIFYYFFYYFFFYFFFYFFYF FFYSYYFYFFFFFYFYFYYYFYFF YYVYFYFY FFFVFF FY FFYY FVYVFFFSFFVFYFYFF YFFFSFYYVFVFYYYFFYFFFVVFFFYF FYFIYFFF F VF YYY FFY Y VF F E7B EE RRRRRRRRRRRRRRRRRRRRRRRKRRRRRKRRKRRRRQRRRRRKRRKRKRKRRRRRRKRRRRRRQRKRHRKKRRKRR RNKRRKKRKKR RRRKKKSQRR KKRHRRKRT KKYYYRRKYKKRRYRRFRRSRRKRNYRSDRNYSRRRRRSTHRKSRSRRRSRNSRRYYRKSQR RNRNYRNRRNYSSRRRSQTRNQYR QRRRKYSS RRSSTT DR YERR SNRSYARRAQRVRRSTR KNHAREARRKNRQRTTSRRRHKRRERRT TRRGQRQS S RS KTH EQY R NH S E7 EE YYYYYYYYYYYYYYYYYYYYYYYYYYYYYYYFYYYYYYYYYYYYYYYFYYYYYYYYYYYYYYYAYYYFYYYYYYYYY YFYYYYYYYYY YYYYYYYYYY YYQYFQYQL YYYYYFYFYYFYYYFQTFYYFQYQIYFYYQLYYMFYYYYLLMFYYYQHVYQYYQFYYTYYQF QYYLYF QLIYYYYQYYQYQMQYF QQYQFYYV YFYFFQ YY YQQQ YIQ YYIQYYFEQVYL YIYFQYQYYFLV YLYFYYQYYYYHFV YYYYLYLY Y YY YYI YYY F VL Y E6B EE VVVVLLVLLVLVLVVLLVVVLVLQVVLLLQLLQVLQLVLLLLVQLLQIQVQLQLLILQLLVQLIQQQLQIQQLLQVL MQQMQLLMLML LMILLMSQMV LLVLLVLVV MLLLLILILLILLLLIQLILIVQVILLQLIILIDLQLLLDLDIQLLVLVQDLHVLLLVQLVL ILQILI ILILQLVVVLVLVILL VVLIQLIL LIQYDV LQ LVVV LII LSVVLLIIVIED LDLIVLVLQLLL LDLVLLVMLLLLIT SLLVILIL L VL QQD LKL T DI I E1B EE MMMMRRMRRMRMRMMRRMMMRMRLMMRRRLRRMMRLRMRRRRMLRRLMLMLRLRRSRLRRMMRMLMLRMQLLRHLSH QMLQLQMQQMR HQSQQLQLQM MQESEEMES QQSSSLELDQLEESEDREEALELSSDEVSESDSDEASEDSSDLAQEEDEAEQADEDDELDSN ELMETQ EDDEAMMEMDSSDDID AEKEKSQE EGAESE QL DEEE ASE DAEEADEDEELE QGAEEEEQAQDA SSGKERIQQSQEEE AENNEEEE D QD GAA QNS D QE Q 2 KKKKTTKTTKTKTKKTTKKKTQTSKKTTTSTTKKTSTKTTTTKSTTSKSKSTSTTQTSTTKNTQSNTTVRSSTTSPT QSRESQMEQKT TANQQKKSAK TQASNTLTP KQMESTNAQKTNNSNVANNSTTSQPQNPSVPQSTNSDNASRTSSAQVQTSVESQSQQLSTQN TRVASD SDSQSRKTKAQSDSVQ QVDQKSQN NDSNVL TT QLIV SPI QSKTSDGSVTTV QESRLQVNMPDV SAIDITAKNDFEES SVRVQIQS A A TSS KSS E PT T 6 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPAPPAPPPPPAPPPPPPPPPPPPPPPPPPPAP PAPPPPPPPPP PPPPPPPPPP PPSPVPPPP PPPPPPVPPPPVIPIPPVVPPPPPPPVPPPPPPPVPVVPAPPPPPPPPSPPPPPVPPPPLPV PPPSPV PIPAPPPPPPPPPPPP PPIPPPPP VVPVPP PP PPPP PPP PPSPPVVPPPPP PVPPPPPTPAIP PAAVVPPPPVPPVP PVVAPVPA P D PP PPP P PP 7B TTTTEESEETETETTEESDDEDESSSEEESEESDESENEEEETSEESDSTSDSEEDESEETSEDTSSESDSSEESDQ YSSYSTNYTNE EYDTTYSTYT STDDDDSDS YTDDDDEDEEDEEDEETEESDDSSSEESDDSEEVEDESDEVVDDSEDTDDDSDSDEEDSGDE DTAEDE DTEKDTTDTDDDDEDE DEDDDDSA EEDEED SG EDEE SSD ENGDSQQEQDLE SNSEDEGDSTTD DDESEVETDESSED SEEEDEDE D S DSV NSD K EN 6 LELLEDLDELELELLEELLTELEMLLEEELEDLLEMELEEEELLEELLMLLEMEELELEELLELLLLDLLLFDELLE ELLEMEEEEED EELEEELLEL IEDYQDISL EEYYYLQLLVLQQYQSLQQYLVLSLLQYYD QLKQYQQEVLKLYEKFSKYDDYTKQQSLQKQ SLEQYQ RKEQYLLTLEKYSERQ KSYRLYDT QKYQTK LE QRTS ELT QESAEMEETKLT EVEKQASYQLKQ YVLYPEKLYQELQL EPPLVPRL E K YYL EFY L T 6 PPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPPP PPPPPPPPPPP PPPPPPPPPP PPPPPPPPA PPPPPPPPPPPPPPPPPPPPPPPPAPPPPP PPPPPPPPPPPPPPMPPPPPPPPPPPPPPPA PPPPPP PPPPPPPPPPPPPPPP PPPPPPPP PPPPPP PD APPP PAP PPPPPPPSPPPP PPPPPPPPPPPP PPPPPPPPPPPPPP PPPPPPPP P P PPP PPP P P 4B VLIVVVIVVIVIVIVVVIVIVVVVIIVVVVVIVIVVVVVVVVIVVVVLVVVVVAVFVVVVVMVIVLMVVETMVVVSV TMVTVTVTAVV VTITTTMVTI LTIVIIVVV TTVVVVFTLTLIIMIVLITIIVVILLIEVV LIVIITVL EVAVLVVIIVVLVIILLVVLVV VPLVTI VNFLVPVVILIVIFVL IIIIEVVL ILVIIV LV LVII LKV LLVVLLIIIITI ILLLIIIIIVNI V LMLV IIAVVIV LLLLILVL L F VVE VIM Q I 4B RRRRKTHTKRKRKRRKKHRRKTKKYHKKKKKKKRTKKRSKKTHKKKKRKRKKKKTRKHNNRKKRRKKKKLKKKQKHH AKKSKKKTTKK QAKKKKIRAR HIKASKQKH SKIQVASQTKHTTIT KTTTAKKKHKTKVR TKKTNTTS QKKITFKKKNRQMKSTTKKTKS RKVKTN KSTSVKRRRTKVKSST KKSKYVQN TTVT K TK TKKR SHR TSKKSNTSKKQK KSSKSKSTKSK V NSAN ASAQSNV SNNNKAKN S T TQK KKV T S 6 RRRRRRRRRRRRRRRRRRKRRRRKRRRRRKRRKRRKRRRRRRRKRRKRKKKRKRRRRKRRRKRRKKKRSRKKRRKRR KNKKKKKKRKR RKRRRKKKKR KK KR K R KRKRKKRKRKKRRKR RRRKK K RRRRK RR RKRQR H KKRR K K RRR KR R RK RR RRRKRR RR KPR R R KKQR RRRR KK Q RR RR RRRR R RR R RHKR K R RR KRRQ RK RRRS R R R R R K K R 8 DDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDNDDDDDDDDDDDDDDDDDEDDDDEDDDDGD DDDDDDDDDDD EDIDDDDDDD ED DD E S DDDDDDDDDDDDDDD DDDDD D EDDED DD DDDDD D DDDD D D DDD DD D LD DD DDDDSD DD DDD D D TDDD DDDD D D DD DD DDDD D DT D DNED D D D DDD DD DS D D D D D D D D 9 SSSSSSSSSSSSSSSSSSSSSSSGSSSSSGSSGSSGSSSS SSGSSGSGSGSGSSSSGSSSGSSGGGSGSGGSSGSS SGGSG SSASS SSSAAAAGSS SA A S S S S GS GS G S S G G S A SS S A S A S A S GG A AG A S 9 *