Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -5 -5 -6 -7 -5 -4 -6 -7 -6 -2 0 -5 11 -4 -7 -5 -5 -5 -5 -3 0 0 0 0 0 0 0 0 0 0 6 0 94 0 0 0 0 0 0 0 3.03 2.19 2 T -2 -4 3 3 -5 -2 2 -3 -3 -5 -6 -1 -4 -6 -2 3 5 -7 -5 -4 2 1 13 13 0 1 14 1 1 0 0 3 0 0 2 17 29 0 0 1 0.75 2.25 3 A -1 -5 -6 -6 -2 -5 -5 -6 -2 4 2 -5 4 2 -3 -5 -2 -2 2 3 5 0 0 0 1 0 1 0 1 24 16 1 10 8 1 1 2 0 7 21 0.76 2.25 4 T -3 1 0 -3 -4 1 0 -5 1 1 -1 0 -2 -4 -5 0 5 -5 -3 1 2 6 5 1 0 5 6 0 3 9 6 7 1 1 0 8 29 0 1 10 0.42 2.25 5 L -5 -6 -6 -7 -3 -6 -7 -8 -4 7 3 -6 -1 1 -6 -6 -3 -4 -2 2 0 0 0 0 0 0 0 0 0 55 22 0 1 5 0 0 1 0 1 12 1.40 2.26 6 R -4 8 -4 -4 -5 -2 -2 -6 -3 -5 -5 -1 -4 -6 -5 -4 -3 -7 -5 -5 1 87 0 1 0 1 2 0 0 1 1 2 0 0 0 1 1 0 0 1 2.19 2.28 7 D 0 1 -1 0 -4 0 1 -5 0 -3 -1 1 -3 -3 6 -1 0 -4 -4 -3 8 8 2 6 0 4 10 1 3 2 6 7 1 1 31 4 5 0 1 2 0.57 2.29 8 A 5 -5 -5 -6 -1 -4 -4 -3 -4 1 0 -5 4 0 -2 -2 -3 0 -1 0 49 1 0 0 1 0 1 2 0 7 10 0 9 4 2 2 1 1 2 7 0.80 2.29 9 V -1 3 -1 -2 -2 1 2 -3 -1 -2 -3 0 -3 -5 -5 0 5 -4 -4 0 4 15 2 2 1 6 13 2 2 2 3 5 1 0 0 5 29 0 0 6 0.51 2.30 10 A 1 0 -3 0 -4 -1 3 -4 -1 -1 -1 0 -1 -4 5 -1 -2 -2 -4 -1 12 5 1 4 0 3 16 1 1 4 7 5 1 1 26 4 3 1 1 4 0.48 2.30 11 A 3 -1 -1 3 -4 0 4 -1 -1 -5 -5 0 -4 -5 -4 1 0 -3 -5 -4 20 3 3 15 0 4 22 5 1 0 1 5 0 0 1 12 5 0 0 1 0.51 2.31 12 D -5 -5 -2 8 -5 -3 -1 -5 0 -6 -7 -4 -5 -6 -5 -4 -5 -8 -5 -6 0 0 1 90 0 0 3 0 2 0 0 0 0 0 0 0 0 0 0 0 2.38 2.31 13 L 4 -3 -3 -4 0 -4 -3 -4 -3 2 3 -4 0 -1 -5 -3 -2 4 -1 2 28 2 1 1 2 1 2 1 1 11 22 1 2 3 0 1 2 5 2 11 0.50 2.31 14 R 1 -1 -2 3 -4 0 3 -2 -1 -4 -4 0 -4 -5 5 -1 -2 -4 -4 -4 13 3 2 13 0 4 17 3 1 1 1 5 0 1 26 4 2 0 0 1 0.63 2.30 15 S 4 0 -3 0 -3 1 1 0 -1 -3 -2 -2 -2 -1 -3 -1 -1 -3 -3 -1 36 6 1 5 0 7 8 6 1 2 4 3 1 3 1 5 4 0 1 4 0.38 2.28 16 I -4 -5 -6 -7 -2 -5 -5 -6 -4 5 3 -5 2 0 -5 -5 -4 1 -1 3 1 0 0 0 1 0 0 0 0 34 26 0 4 4 0 0 1 2 2 19 0.96 2.28 17 T 2 1 -3 -4 0 0 -3 -4 2 0 2 -2 0 0 -5 -2 0 4 0 1 15 8 1 1 2 4 2 2 5 4 19 2 3 3 1 3 5 4 3 10 0.23 2.27 18 E 3 2 -1 2 -4 1 3 -2 -1 -5 -4 0 -3 -5 -1 -1 -1 -4 -4 -4 24 11 2 11 0 5 20 2 2 1 1 4 1 1 3 5 3 0 1 1 0.44 2.25 19 I -2 -4 -4 -5 -2 -4 -5 -5 -3 5 3 -5 3 1 -5 -4 -3 2 -2 1 3 1 1 1 1 1 1 1 1 31 30 1 6 5 1 1 1 3 1 9 0.80 2.18 20 Y -2 1 -2 -3 -1 -2 -1 -4 2 1 0 -3 0 2 -4 -3 -2 4 6 0 3 7 2 2 1 2 5 2 5 8 10 1 3 8 1 2 2 6 23 6 0.48 2.06 21 R 1 3 4 -1 -2 1 0 -2 0 -3 -2 0 -2 -3 -3 -1 -1 -2 -2 -2 12 16 20 3 1 7 6 3 2 2 5 5 1 1 1 5 3 1 1 3 0.32 2.05 22 E 0 0 -1 3 -2 3 3 -3 3 -4 -3 -1 -2 -3 0 -1 -2 1 0 -3 9 5 2 15 1 10 17 2 8 1 3 3 1 1 6 4 2 2 3 2 0.34 2.05 23 S 2 -3 -2 -1 0 -2 -1 0 2 0 -1 -2 -1 0 1 0 0 -1 3 0 17 2 2 3 2 2 4 7 4 4 5 2 1 3 6 7 6 1 10 7 0.11 1.96 24 V 0 -2 -3 -2 -1 -2 -1 -3 -1 3 0 -2 0 0 -2 -1 -2 3 0 3 6 3 2 3 1 2 4 3 1 18 9 2 3 5 2 4 3 3 3 20 0.24 1.97 25 L 1 2 -2 0 -2 0 2 -3 -1 -1 0 -1 -1 -2 0 -1 -1 -1 -1 0 11 12 2 6 1 4 12 3 2 4 11 4 2 2 5 5 4 1 2 7 0.08 2.03 26 N 0 0 2 2 -2 0 2 0 3 -3 -3 -1 -1 -2 -2 0 1 -1 0 -3 7 5 9 10 1 4 12 6 7 2 3 3 1 2 2 7 9 1 3 2 0.16 2.01 27 G -1 2 -1 -1 -2 -1 0 2 0 -3 -2 -1 -1 -1 -2 1 2 1 0 -3 5 11 3 4 1 3 6 17 2 2 4 3 2 3 3 9 13 2 3 2 0.15 2.04 28 V 0 -1 0 -1 -1 0 -1 -1 1 0 1 -2 2 0 0 -1 1 0 0 0 8 4 5 3 1 4 5 5 4 5 11 3 4 4 4 3 10 1 3 6 0.00 2.09 29 A 3 -1 -2 -1 -1 -2 -1 0 0 0 -1 -2 -1 0 -1 0 -1 1 0 0 27 4 2 3 1 2 4 6 2 6 6 2 2 4 3 6 4 2 4 7 0.14 2.08 30 T 0 -1 -1 -1 -1 -1 0 -2 -1 0 -1 -2 0 0 -1 1 4 0 0 -1 7 4 3 4 2 3 5 3 2 5 7 2 2 4 4 10 20 2 3 5 0.11 2.10 31 Y 0 -2 -2 -2 -1 -1 -2 -1 0 -2 0 -2 0 5 -1 -2 -2 5 4 -2 8 3 2 3 2 2 2 4 2 2 8 2 2 23 3 3 2 6 13 3 0.43 2.14 32 E -1 0 0 3 0 1 3 -1 1 -2 -2 -1 0 -1 0 -1 -1 1 0 -2 4 4 4 13 2 6 20 4 3 2 4 3 3 3 5 4 4 2 3 3 0.17 2.18 33 E -2 0 -1 0 1 0 1 -1 1 -1 -1 0 1 -1 0 -1 1 2 2 -1 4 4 3 6 3 4 11 5 3 4 8 6 3 3 5 5 7 3 7 4 0.02 2.21 34 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 35 P 0 0 -1 -1 0 -1 0 -2 0 -1 -1 -1 0 -1 4 -1 -1 1 0 0 9 5 3 4 2 3 7 3 3 3 5 4 2 3 22 4 4 2 3 6 0.20 2.21 36 P -1 0 -1 0 0 0 0 -2 2 -1 -1 -1 1 0 3 -1 -1 3 0 0 5 6 3 6 2 4 5 4 4 4 5 4 3 4 14 5 4 3 4 6 0.09 2.23 37 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 38 E 0 0 -2 0 0 -1 1 -3 0 0 0 -2 0 -1 1 -2 -1 3 0 1 7 5 2 5 2 3 10 2 2 5 11 3 3 3 8 3 4 4 3 11 0.06 2.24 39 A 1 -1 -1 2 -1 0 3 -2 0 -2 -3 -1 -1 -1 1 -1 -1 1 -1 -2 13 4 3 9 2 5 18 4 3 2 3 4 2 2 6 5 4 2 3 3 0.14 2.24 40 E 0 0 0 1 1 1 2 -1 1 -1 -2 -1 1 -1 -1 0 -1 3 1 -2 7 4 4 8 2 6 14 4 3 3 4 4 3 3 3 6 4 4 5 4 0.07 2.24 41 M -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 42 A 1 2 -1 0 1 1 1 -2 1 -1 -1 0 1 -1 -1 -1 -1 2 0 -1 10 10 3 4 2 6 8 4 3 4 7 5 3 3 3 4 4 3 4 4 0.03 2.23 43 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 44 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 45 F -2 -1 -2 -2 0 -2 -2 -3 0 2 2 -2 1 4 -2 -2 -2 4 2 -1 4 4 2 3 2 2 3 2 3 11 17 2 4 14 2 3 3 6 5 4 0.25 2.24 46 S 1 1 0 1 1 1 1 -1 1 -1 -1 0 0 0 -1 0 -1 2 0 -2 10 7 4 7 3 5 9 4 3 3 6 5 3 4 3 6 5 3 3 3 0.02 2.24 47 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 48 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 49 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 50 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 51 N -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 52 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 53 Y -1 1 1 0 1 0 -1 -2 3 -2 -1 -1 0 1 -1 -1 -1 2 3 -1 5 8 6 5 3 3 5 4 7 3 7 3 2 6 3 4 4 2 10 4 0.10 2.21 54 P 0 1 -1 -1 1 0 -1 -1 2 -1 -2 -1 1 0 3 0 0 2 0 -1 8 7 4 3 3 4 4 4 4 4 5 3 3 4 12 6 5 3 4 5 0.06 2.20 55 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 56 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 57 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 58 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 59 L 2 0 -2 -1 1 -1 1 -2 0 1 0 -2 0 -1 -2 -2 -1 1 0 1 16 4 2 4 3 2 10 3 2 7 9 3 3 3 2 3 4 2 3 11 0.07 2.17 60 D -2 -1 0 2 1 0 4 -2 1 -2 -2 -1 0 -1 -1 -1 -1 2 0 -1 4 4 4 12 3 3 22 3 3 3 4 4 3 3 3 4 4 2 3 4 0.19 2.21 61 E -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 62 R 0 -1 2 4 -1 1 1 1 0 -3 -4 -1 -2 -3 -2 -1 -1 -1 -3 -3 7 3 9 23 1 5 10 10 2 2 2 3 1 1 2 5 5 1 1 2 0.32 2.24 63 G -2 -1 0 2 -2 -2 -1 5 0 -3 -4 -2 -2 -3 -2 -1 -2 -1 -3 -3 3 3 5 10 1 2 4 45 2 1 2 3 1 1 2 4 3 1 1 3 0.64 2.20 64 A 0 2 -1 -1 -1 2 3 -2 0 -1 -3 2 -1 -3 -1 -1 0 0 -2 -1 8 9 3 3 2 9 17 4 2 4 3 10 2 1 3 3 6 1 1 6 0.16 2.24 65 V -1 -2 -2 -1 0 -2 -2 -2 -1 3 0 -2 1 -1 0 -2 -2 1 -1 3 4 2 2 4 2 2 3 3 2 17 10 3 3 2 6 2 3 2 2 21 0.23 2.24 66 I 1 -1 -1 -1 1 0 -1 -1 1 1 0 -2 1 -1 -2 -2 -1 3 0 3 11 3 3 3 3 4 4 6 3 7 7 3 3 3 3 3 4 3 3 17 0.07 2.23 67 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 68 Y -2 -1 -1 -2 1 -1 -1 -2 1 -1 0 -2 1 3 -2 -1 0 4 4 -1 3 3 3 3 3 3 4 3 3 4 8 3 3 12 3 5 6 5 13 5 0.21 2.22 69 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 70 Y -1 -1 0 -1 2 0 -2 0 2 -1 -1 -1 1 1 -2 0 0 3 3 -1 6 4 4 3 4 4 3 8 4 4 6 3 4 6 3 8 6 3 10 4 0.07 2.23 71 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 72 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 73 A 0 1 0 0 -1 0 -1 -1 0 -1 -1 -1 -1 0 4 -1 -1 2 -1 -1 8 8 4 5 2 4 3 5 2 4 5 4 2 4 17 5 4 2 2 5 0.11 2.16 74 F -2 -2 0 -1 0 -1 -1 -2 1 0 0 -2 0 4 -1 -2 -1 4 3 0 4 3 5 4 2 3 4 4 4 6 7 2 2 14 4 4 3 4 9 8 0.16 2.13 75 R -1 3 1 0 0 0 -1 -1 1 -2 -2 0 0 -1 -1 1 -1 2 0 -1 4 15 6 5 2 4 4 5 4 3 5 5 2 2 4 11 4 3 4 4 0.08 2.17 76 N 0 -1 1 1 1 0 0 0 1 -1 -2 -1 0 -1 1 0 1 2 -1 -2 6 4 6 8 3 4 6 8 3 3 4 4 3 3 8 6 7 3 3 3 0.03 2.20 77 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 78 T 0 0 0 1 1 0 0 -1 1 -1 -1 0 1 -1 2 -1 0 2 0 -1 7 4 4 7 3 4 7 6 4 4 5 6 3 3 9 5 5 3 3 4 0.02 2.23 79 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 80 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 81 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 82 F -1 1 -1 -1 0 0 0 1 4 -1 -2 -1 0 0 -2 -1 -1 4 1 -2 4 7 3 4 2 4 7 12 10 4 4 4 2 3 3 4 4 5 5 4 0.13 2.20 83 L 1 -1 -1 -1 2 -1 -1 0 1 0 0 -2 1 -1 -2 0 1 2 0 1 10 3 3 3 4 3 3 6 3 6 8 3 3 3 3 6 9 3 3 8 0.02 2.21 84 V -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 85 E -2 -2 0 -1 0 -1 2 -2 0 3 2 -2 1 0 -3 -2 -2 2 0 0 3 2 4 3 2 3 13 3 2 14 17 2 3 3 2 3 3 2 3 7 0.15 2.25 86 D -1 -1 -1 1 1 0 0 0 2 1 0 -1 1 0 -2 -2 0 3 0 0 5 3 4 8 3 4 7 7 5 7 9 3 3 4 3 3 5 4 4 6 0.02 2.24 87 S -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 88 I -1 -2 -2 -2 1 -1 -2 -2 0 2 1 -2 2 1 -2 -2 -1 2 3 1 5 3 3 3 3 3 3 3 2 12 11 3 5 6 3 3 3 3 10 11 0.15 2.23 89 Y -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 90 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 91 S -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 92 P -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 93 E 1 0 1 3 0 1 2 0 1 -3 -3 0 -1 -2 -1 0 0 1 -1 -3 10 5 6 15 2 5 12 7 3 2 3 5 2 2 3 8 5 2 2 2 0.18 2.13 94 A -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 95 R -2 5 -1 -2 1 2 -1 -2 1 -2 -2 0 0 -1 0 -1 0 4 0 -1 4 26 3 3 3 9 3 3 4 3 4 5 3 3 5 4 6 5 3 4 0.36 2.15 96 G -2 2 0 -2 1 -1 -2 5 1 -2 -3 -1 0 -1 -1 -1 -2 -5 -1 -2 3 11 5 3 3 3 3 35 3 3 3 4 3 3 3 4 3 0 3 3 0.41 2.14 97 K -2 4 -1 -2 0 3 -1 -2 2 -2 -2 3 0 -2 0 -1 -1 0 -1 -3 3 17 3 2 2 12 3 3 5 2 4 17 3 2 4 4 4 2 2 2 0.31 2.20 98 G -2 -2 -2 -3 -1 -2 -3 7 -1 -4 -4 -2 -6 -3 -3 -2 -3 -6 -2 -4 2 2 2 1 1 1 2 69 2 1 2 2 0 1 1 2 1 0 1 1 1.29 2.18 99 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 100 G 1 -2 -2 -3 0 -2 -3 6 -5 -3 -4 -3 1 -2 -2 -2 -2 1 -2 -3 13 2 2 2 2 2 2 49 0 2 2 2 3 2 2 3 2 2 2 2 0.77 2.22 101 K -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 102 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 103 L 1 -5 -1 -5 1 -1 -5 -2 1 0 3 -5 4 1 -1 -1 -1 -5 0 0 10 0 3 0 3 4 0 4 4 5 26 0 8 7 3 4 4 0 3 6 0.26 1.95 104 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 105 S 1 2 0 0 2 2 1 -2 1 -2 -1 0 0 0 -2 -1 -1 2 0 -2 10 9 4 5 4 8 10 3 3 3 5 5 3 4 3 4 4 2 4 3 0.06 2.25 106 E 3 0 -2 -2 0 0 1 -2 3 -2 0 -1 0 0 -2 -1 -1 3 0 -1 21 5 2 3 2 4 8 3 7 2 8 4 2 4 2 4 4 4 3 4 0.13 2.28 107 L -1 0 0 0 3 0 -1 -1 2 0 -1 -4 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 0 5 5 5 5 5 5 5 5 0.07 2.12 108 V -1 -1 -1 -2 1 -1 0 -3 0 2 2 -2 2 0 -2 -2 -1 2 -1 1 6 3 3 3 3 3 6 3 2 11 20 3 4 4 3 3 3 2 3 8 0.11 2.18 109 G 1 1 0 2 0 1 2 -1 1 -2 -3 0 1 -2 -2 -1 0 0 -1 -2 12 6 4 12 2 6 13 5 3 2 2 6 3 2 2 4 5 2 2 2 0.13 2.21 110 R 1 1 -2 -1 0 0 1 -3 3 0 -1 -1 0 0 -3 -2 -1 6 3 -1 10 8 2 3 2 5 8 2 6 5 7 3 2 4 1 2 3 9 8 5 0.21 2.21 111 C 5 -3 -3 -2 3 -3 -3 -2 -2 -2 1 -3 0 1 -3 -1 -2 0 -2 -2 42 1 1 2 6 1 1 3 1 3 14 1 3 5 1 4 2 1 1 3 0.51 2.23 112 T -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 113 A -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 114 L -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 115 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 116 F -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 117 R -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 118 Q -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 119 M -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 120 I -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 121 A 1 -2 -1 -2 1 -1 -2 -1 0 -1 3 -2 0 0 -2 -1 -1 4 0 -1 13 3 3 3 3 3 3 5 2 3 24 2 3 4 2 5 3 5 3 4 0.15 2.25 122 V -1 -1 0 0 2 -1 2 -1 0 -1 1 -2 0 0 -3 0 0 3 0 0 4 4 4 5 4 3 11 6 3 3 13 2 3 3 2 7 5 4 3 6 0.05 2.26 123 I -2 -3 -3 -3 2 -3 -2 -4 -1 3 -2 -3 0 -2 -3 -2 1 0 -1 5 3 1 1 2 3 1 3 2 2 13 3 1 2 2 2 3 10 1 2 39 0.56 2.27 124 G -1 0 0 0 2 0 -1 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.04 2.23 125 G 1 -1 -1 1 1 0 1 -1 1 -1 -2 -1 0 -1 1 1 0 2 0 -1 11 4 3 7 3 4 9 5 3 3 4 4 2 3 6 10 6 2 3 5 0.05 2.19 126 A -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 127 H -2 0 6 -1 1 -1 -2 -2 1 -2 -2 -1 1 -1 -2 -1 -1 2 -1 -2 3 5 41 4 2 3 3 3 3 3 4 3 4 3 3 3 3 2 3 3 0.66 2.13 128 P 0 0 -1 1 0 1 2 -2 1 -1 -2 0 0 -2 2 -1 1 1 -1 -1 8 5 3 6 2 5 15 3 3 3 4 6 2 2 11 3 10 2 3 4 0.16 2.12 129 S -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 130 S -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 131 I -1 2 0 -1 1 1 0 -2 3 1 0 -1 1 0 0 -2 -1 3 0 0 5 10 4 4 3 6 5 4 6 9 9 4 4 3 5 3 4 3 4 5 0.11 2.03 132 A 2 4 0 0 0 1 -1 0 2 -2 -3 1 -1 -2 -1 -1 -2 1 -1 -3 16 18 4 4 2 6 4 7 4 2 3 9 2 2 4 5 3 2 3 2 0.23 2.07 133 L -1 0 1 -4 3 1 0 -1 -4 0 -1 -4 2 1 0 0 0 4 2 0 6 6 6 0 6 6 6 6 0 6 6 0 6 6 6 6 6 6 6 6 0.17 1.78 134 H -1 -2 -1 -2 2 -1 -2 -1 3 -1 -1 -2 1 1 -2 0 -2 3 6 0 5 3 3 3 4 3 3 6 6 3 6 3 3 4 3 6 3 4 27 6 0.45 1.99 135 R 0 2 -2 0 -1 1 4 -2 2 -2 -1 1 1 -2 -2 -2 -1 1 -1 -2 7 11 2 5 2 6 24 3 4 3 7 9 3 2 2 3 3 2 2 2 0.28 2.03 136 A 1 4 -1 -2 -1 0 -2 -1 2 -3 -4 4 -1 -3 -2 1 -2 0 -2 -3 10 19 2 2 1 3 2 5 4 1 2 28 1 1 2 9 2 1 1 2 0.50 2.06 137 L -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 138 G -1 0 0 0 3 1 0 -1 2 -4 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 0 5 5 5 5 5 5 5 5 5 5 0.13 2.01 139 F -2 -1 -5 -2 1 -1 -2 -2 -4 -4 -2 -2 1 7 -1 -2 -1 3 3 -2 3 3 0 3 3 3 3 3 0 0 3 3 3 42 3 3 4 3 9 3 0.82 1.91 140 E 0 2 -1 0 0 2 3 -3 3 -1 -3 1 0 -2 -2 -1 0 1 -1 0 7 12 2 5 2 8 16 2 6 3 3 9 2 2 2 3 5 2 2 7 0.23 1.98 141 L -1 2 -1 -1 -1 2 2 -3 1 0 -1 1 1 -2 0 -1 -1 0 -1 -1 5 9 3 3 2 8 15 2 4 6 7 7 4 2 6 5 4 1 2 5 0.15 2.01 142 Q -1 -2 -1 0 1 -1 3 -3 -1 1 -2 -2 -1 -2 -3 -2 0 5 -1 3 6 2 3 4 3 3 17 2 2 8 4 2 2 2 1 2 7 7 2 21 0.32 2.04 143 G -1 0 0 0 3 0 0 -1 2 0 -1 0 2 1 0 -1 0 4 1 -1 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 0.09 2.12 144 L -2 3 -1 -1 1 0 -1 -2 3 0 -1 -1 0 -1 -1 -1 2 2 0 1 3 15 3 3 3 4 5 3 6 6 6 3 3 3 3 4 13 2 3 9 0.17 2.13 145 M -1 2 -2 -2 0 -1 -1 -3 2 0 1 -1 2 3 -2 -2 -1 1 2 -1 4 12 2 2 2 3 4 3 4 6 15 3 5 12 2 4 4 2 6 4 0.22 2.12 146 K -2 4 -2 -2 -1 -1 2 -3 2 -3 -4 3 -1 -3 4 -1 -1 0 -1 -2 3 19 2 2 1 3 11 2 4 2 2 15 2 2 18 4 3 1 2 3 0.47 2.12 147 A -1 2 2 1 0 2 3 0 2 -3 -3 2 0 -2 -3 -1 -3 1 -2 -3 5 10 8 9 2 8 15 6 4 2 3 11 2 2 1 5 2 2 2 2 0.25 2.10 148 T 1 -3 -1 -1 2 -1 -2 -3 2 1 -2 -2 1 0 -2 0 0 1 3 3 12 2 3 3 4 2 3 3 5 7 4 2 3 4 2 6 6 2 11 18 0.24 2.05 149 G 2 -2 -2 -2 -1 -3 -2 4 -1 -1 0 -1 0 0 -2 -2 -2 0 1 -1 14 2 2 2 2 1 2 33 1 4 8 3 2 4 3 3 3 1 5 5 0.39 2.04 150 F -3 2 -2 -2 0 -1 -1 -4 1 -1 0 0 0 4 -1 -3 -2 4 5 -2 2 9 2 3 2 3 5 2 4 4 8 6 2 15 3 2 3 4 19 3 0.46 2.11 151 K -2 2 -2 -1 -2 -1 -2 -2 0 1 0 4 1 -2 -2 -1 -1 0 1 0 3 11 2 4 1 2 3 3 2 9 8 24 3 2 2 4 3 1 5 7 0.27 2.09 152 H -1 -1 3 4 -2 0 -1 0 4 -4 -2 -1 -1 3 -3 -1 -3 -1 -1 -3 5 3 14 22 1 4 4 7 8 1 4 4 2 12 1 4 2 1 2 2 0.42 2.11 153 G -2 -3 0 2 -2 -3 -1 6 -2 -5 -5 -3 -4 -4 -2 -2 -3 -3 -3 -4 2 2 5 11 1 1 4 62 1 1 1 1 1 1 2 2 1 1 1 1 1.19 2.12 154 R -1 4 -1 -1 -2 2 2 -1 1 -2 -4 2 -2 -3 -2 -2 0 -5 -2 0 5 19 3 4 1 10 15 5 3 2 2 10 1 1 2 3 5 0 1 7 0.34 2.07 155 W -3 0 -2 -2 -2 -2 -1 -3 0 -2 -1 -2 -1 2 -2 -3 -3 9 5 -2 2 5 2 2 1 2 4 3 2 2 5 3 1 8 3 2 2 27 20 4 1.05 1.99 156 L -2 3 -3 -3 -1 -1 1 -4 4 1 1 -2 0 -1 -3 -2 -2 2 3 2 4 13 1 2 1 3 8 1 9 7 13 2 3 3 1 2 2 2 8 14 0.29 2.02 157 D -3 -4 1 8 -2 -2 -1 -2 -1 -5 -6 -3 -4 -5 -3 -2 -3 -7 -4 -5 2 1 6 72 1 1 3 2 1 1 1 1 1 1 1 3 2 0 1 1 1.64 2.10 158 T 2 -3 -1 0 0 -3 1 -3 0 0 1 -2 2 -3 -4 -1 2 -3 -3 2 18 1 3 6 2 1 9 2 2 4 12 2 6 1 0 5 11 0 1 14 0.24 2.13 159 A -1 -3 -4 -2 -1 -4 -2 -4 1 3 1 -4 0 0 -5 -3 -1 1 3 4 5 1 1 2 1 1 3 2 3 17 15 1 2 3 0 1 3 2 10 26 0.50 2.16 160 F -3 -1 -4 -4 -1 -3 -4 -5 2 3 2 -5 2 2 -5 -3 -2 6 3 2 1 4 1 1 2 1 1 1 4 15 21 1 4 8 1 2 2 8 8 14 0.57 2.17 161 M -4 -5 -6 -6 -3 -4 -5 -6 -3 -2 1 -5 9 2 -5 -5 -4 3 4 -2 0 0 0 0 0 0 0 0 1 1 12 0 57 7 0 0 0 4 13 2 1.76 2.18 162 Q 1 1 -3 -3 -3 4 3 1 0 -3 -3 -2 -2 -4 -5 -1 -2 3 1 -1 12 7 1 1 1 19 20 11 2 1 2 2 1 1 0 5 2 4 4 4 0.47 2.17 163 R -4 5 -4 -4 -2 -2 -4 -6 -2 -3 2 5 -1 -4 -5 -4 -4 -3 -2 -3 1 28 0 1 1 1 0 0 1 1 22 35 1 1 0 1 1 0 2 1 1.00 2.17 164 P -1 2 -2 1 -2 -1 1 -5 -1 1 1 0 1 0 2 0 0 -1 -3 -1 5 11 2 7 1 3 9 0 2 9 12 5 3 5 9 6 6 1 1 3 0.15 2.18 165 L -3 -1 -5 -5 -3 -4 -5 -6 -5 3 6 -4 -1 -1 -5 -5 -4 -3 -3 -1 2 4 0 1 0 0 1 0 0 13 70 1 1 2 0 1 1 0 1 2 1.23 2.17 166 G 1 -1 2 3 -3 -1 0 4 0 -4 -4 -2 -4 -4 0 0 0 -3 -4 -4 12 3 10 14 1 3 5 28 2 1 1 2 0 1 4 5 5 0 0 1 0.47 2.13 167 E 0 -1 -2 4 -6 0 5 -1 -2 -5 -5 -1 -4 -4 3 -1 -2 -6 -4 -4 9 3 2 19 0 3 31 4 1 1 1 3 0 1 13 4 3 0 0 1 0.70 2.09 168 G 0 0 0 1 -3 0 -1 4 5 -4 -4 -2 -4 -2 1 -1 -2 4 0 -4 6 4 4 7 1 3 5 27 11 1 2 2 0 2 7 5 3 5 3 1 0.46 2.06 169 T 1 0 -1 3 -3 -1 0 -1 0 -3 -2 -2 -2 -4 3 1 2 -1 -4 -1 13 6 3 14 1 3 6 4 2 1 4 2 1 1 12 10 12 1 0 4 0.29 2.09 170 A 3 -1 -2 1 -3 0 1 -1 -1 -4 -3 -3 -4 -5 3 1 1 0 -3 -2 27 3 2 7 1 4 9 5 2 1 3 1 0 0 15 9 8 1 1 3 0.40 2.09 171 T 1 -1 1 2 -4 -1 1 -2 -1 -3 -3 -2 -3 -4 2 2 3 -3 -3 -2 13 3 7 9 0 3 7 3 1 1 3 2 1 1 9 14 18 0 1 3 0.31 2.07 172 K 1 1 -2 -1 -4 2 1 -2 -1 -3 -1 0 -1 -4 5 -2 -1 -4 -4 -3 12 8 2 4 0 8 7 3 2 1 8 7 2 1 26 3 4 0 0 2 0.44 2.08 173 P -2 -3 -4 -1 -4 -1 -1 -3 -3 -4 -3 -2 0 -6 8 -2 -2 -2 -4 -4 4 1 1 3 0 2 3 2 1 1 2 2 2 0 68 2 2 1 1 1 1.72 2.05 174 T 2 -2 -3 1 -3 -1 0 -2 0 -2 -3 -1 -3 -4 3 1 1 -6 -4 1 17 3 1 9 0 3 7 4 2 2 3 3 1 1 15 12 8 0 0 11 0.30 2.02 175 E -1 2 -3 3 -6 -1 4 -3 -1 -1 -4 -1 -1 -1 3 -1 -3 -6 -4 0 5 9 1 15 0 3 22 2 1 4 1 3 2 3 14 5 2 0 0 7 0.43 2.00 176 G 0 2 -3 -1 -4 -2 -3 3 -4 2 -4 -1 -2 -3 3 0 -2 0 -5 -1 7 11 1 4 0 2 2 24 0 10 1 3 1 1 16 6 2 2 0 5 0.42 1.98 177 V 1 -2 -4 -4 -5 -3 -2 -4 -2 2 -1 -3 -1 -3 5 1 0 -1 -2 2 13 2 0 1 0 1 3 1 1 9 5 1 1 1 27 10 7 1 2 14 0.54 1.94 178 Y 0 -1 -2 -1 -4 -3 -2 -4 2 -1 0 -2 -2 4 -1 -2 0 4 5 -2 8 3 2 4 0 1 2 1 5 3 9 3 1 18 4 3 7 4 18 3 0.46 1.96 179 P -1 -2 -4 -2 -4 -2 -2 -4 -5 -3 -6 -3 -6 -4 8 0 -3 -7 -6 -4 5 2 0 3 0 2 3 1 0 2 0 1 0 1 72 6 1 0 0 1 1.90 1.93 180 D -1 -4 -1 4 -6 1 5 1 -2 -3 -3 -1 -5 -6 -1 -2 -2 -7 -6 -4 5 0 2 24 0 5 35 12 1 2 3 2 0 0 3 2 2 0 0 1 0.78 1.89 181 T 0 2 -2 -1 -5 -3 -1 -2 -3 -1 0 -1 -4 -4 2 0 4 -6 -5 1 6 13 2 3 0 1 3 3 1 3 8 4 0 0 9 8 27 0 0 10 0.38 1.76 182 L 0 1 -6 -4 2 -5 -3 -6 -5 1 5 -1 1 1 -4 -4 -2 -2 -2 0 7 8 0 1 3 0 1 0 0 7 48 4 2 6 1 1 3 1 1 6 0.62 1.67 183 Y -3 3 -4 3 0 -1 1 0 2 -4 -4 -1 -2 3 -5 -2 -2 2 2 -1 1 16 0 18 2 3 11 8 5 1 1 2 1 13 0 2 2 3 6 4 0.43 1.58 184 R -4 8 -1 -4 -7 1 -2 -5 -3 -6 -5 3 -4 -6 -5 -4 -4 -6 -5 -6 0 73 3 0 0 6 1 0 0 0 0 17 0 0 0 0 0 0 0 0 1.76 1.49 185 S 3 -3 -3 2 -4 3 -2 -3 -4 -5 -5 1 -4 -5 -4 4 1 -6 -5 -4 28 0 0 10 0 14 0 0 0 0 0 9 0 0 0 30 9 0 0 0 0.70 1.22 K Lambda Standard Ungapped 0.1354 0.3195 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1064 0.3178 PSI Gapped 0.0326 0.2670