#################################
#######  OB-SCORE README  #######
#################################

Files in this directory give the OB-Score for: 

- 225 Omniome proteomes (CMR version 16.0) 
- 16 Ensembl proteomes (downloaded on 10/6/2005)
- 7868 PfamA protein families (version 17.0) 

The compressed tar archive OB_1.0.tar.gz contains perl code that implements
the OB score.

The OB-Score estimates a protein's propensity to produce diffraction-quality
crystals, based on calculated isoelectric point and hydrophobicity values. 
See:

Overton & Barton(2006). "A Normalised Scale for Structural Genomics Target
Ranking: The OB-Score". FEBS Lett. 580, 4005-4009.


The tar archives contain files named according to the organism that the data
pertains to e.g.

"Homo_sapiens.NCBI35.may.pep.fa.OB_score.dat"	
"Methanococcus_jannaschii_DSM2661.OB_score.dat"


Files are tab delimited in the format:
Sequence_identifier	OB-Score

An exception is PfamAid_seqid_OBscore.dat.gz, which has the format:
Pfam_family	Sequence_identifier	OB-Score


The Omniomeseqid_OBscore.dat.gzfile is organised to have a fasta style header
specifying the organism name for each of the 225 proteomes e.g.

>Acinetobacter_sp_ADP1
NTL01AS1042|ACIAD1145   7.20618482
NTL01AS3033|ACIAD3350   7.20618482
NTL01AS2447|ACIAD2677   6.35326695
NTL01AS3126|ACIAD3460   -1.95173040
>Aeropyrum_pernix_K1
NTL01AP02370|APE2303    0.19308664
NTL01AP02628|APE2555    5.02466489
NTL01AP01860|APE1802    -2.93381614


Ian Overton and Geoff Barton (2nd June 2006)