Target Optimisation Utility

Welcome to TarO version 2.0

TarO analyses a protein sequence by a large number of bioinformatics techniques. These include crystallisation propensity prediction, orthologue searching, and many other sequence-based calculations. Results are tabulated and available via an annotated multiple sequence alignment, that can be edited interactively using Jalview.	Login:
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TarO is focused on Structural Genomics target selection/optimisation, but provides annotations that can be informative to a range of biological questions.		TarO Help
TarO connects to available DAS (distributed annotation system) information via Jalview and links to Dasty2, as well as providing routes to other gateways such as UniProt, COG and the Conserved Domains Database. The results of an example TarO query can be browsed here. Guest Access Guest access allows you to try TarO without registering. Although there are no restrictions on guest access, guest results are visible to everyone and will be deleted from the server after a minimum of 8 days.
See here for details on how to obtain a free private account for academic use.
Use Policy We ask users to wait until the results of their submissions become available before submitting any further sequence queries. Results are normally available after 4-12 hours.
Please DO NOT write scripts against this server. If you are thinking about conducting large-scale analyses contact TarO_admin (taro@compbio.dundee.ac.uk).
Authors TarO was developed within the SSPF, primarily by Ian Overton and Geoff Barton with contributions from Jo van Niekerk, Lester Carter, Alice Dawson, David Martin, Scott Cameron, Stephen McMahon, Malcolm White, Bill Hunter and Jim Naismith. Funding was provided by BBSRC under the SPoRT initiative. If you use TarO please cite: Overton et al. (2008) "TarO: A Target Optimisation System for Structural Biology", Nucleic Acids Research (web server issue) doi:10.1093/nar/gkn141. More information on TarO is available here.