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Evidence of Interaction Between TACC3 and RANBP1

The interaction score between TACC3 and RANBP1 is 1.78.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TACC3 and RANBP1 = 0.64

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology N/A N/A
Domains No domains were used in calculating likelihood of interaction N/A
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation No localisation data was used in calculating likelihood of interaction
Transitive Score

The common interactors between TACC3 and RANBP1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TACC3 andRANBP1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TACC3 has 191 interactors and RANBP1 has 336 interactors of which there are 12 common interactors.

Common InteractorName of Common InteractorScore for TACC3-Interactor (?)Score for RANBP1-Interactor (?)
CXorf9 N/A 0.129 0.036
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.068 0.294
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.055 0.044
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.055 0.044
XPO1 XPO1, CRM1: Exportin-1 0.025 19.70
CDK2 CDK2: Cell division protein kinase 2 0.025 0.123
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.025 0.123
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.025 0.263
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.025 69.60
GMNN GMNN: Geminin 0.025 0.027
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.025 0.060
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.025 0.083
0.572
Total Score 1.78