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Evidence of Interaction Between TUBA1 and TEC

The interaction score between TUBA1 and TEC is 37.40.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TUBA1 and TEC = 0.11

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.30E-3
Orthology
OrganismTUBA1 OrthologueTEC OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00179709 0.787 IPI00000879 0.057
human IPI00180675 0.829 IPI00000879 0.057
human IPI00218343 0.848 IPI00000879 0.057
human IPI00410402 0.711 IPI00000879 0.057
human IPI00478908 0.512 IPI00000879 0.057
human IPI00646909 0.602 IPI00000879 0.057
human IPI00179709 0.787 IPI00029132 0.193
human IPI00180675 0.829 IPI00029132 0.193
  • Other

Get References From PubMed
human IPI00218343 0.848 IPI00029132 0.193
human IPI00410402 0.711 IPI00029132 0.193
human IPI00478908 0.512 IPI00029132 0.193
human IPI00646909 0.602 IPI00029132 0.193
human IPI00179709 0.787 IPI00004566 0.252
human IPI00180675 0.829 IPI00004566 0.252
human IPI00218343 0.848 IPI00004566 0.252
human IPI00410402 0.711 IPI00004566 0.252
human IPI00478908 0.512 IPI00004566 0.252
human IPI00646909 0.602 IPI00004566 0.252

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 1.07
Domains Domains present in TUBA1 and TEC:
Domains in TUBA1Domains in TEC
IPR000217 Tubulin
IPR008280 Tubulin/FtsZ, C-terminal
IPR003008 Tubulin/FtsZ, GTPase
IPR002452 Alpha tubulin
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR001849 Pleckstrin-like
IPR001452 SH3
IPR000980 SH2 motif
IPR001562 Tec/Btk domain
IPR011993 PH_type.

The Chi square scores for co-occurrence of domains that are present in TUBA1 and TEC are listed below.

Domain 1Domain 2Chi Square
IPR002452 Alpha tubulin IPR008266 Tyrosine protein kinase, active site 2.84514
IPR002452 Alpha tubulin IPR000980 SH2 motif 1.66314
IPR002452 Alpha tubulin IPR001245 Tyrosine protein kinase 1.24565
IPR002452 Alpha tubulin IPR011009 Protein kinase-like 0.547148
IPR000217 Tubulin IPR011009 Protein kinase-like 0.524874
IPR003008 Tubulin/FtsZ, GTPase IPR011009 Protein kinase-like 0.224946
IPR008280 Tubulin/FtsZ, C-terminal IPR011009 Protein kinase-like 0.224946
IPR000217 Tubulin IPR001452 SH3 0.17131
IPR002452 Alpha tubulin IPR000719 Protein kinase 0.167561
IPR003008 Tubulin/FtsZ, GTPase IPR000980 SH2 motif 0.0551578
IPR008280 Tubulin/FtsZ, C-terminal IPR000980 SH2 motif 0.0551578
IPR000217 Tubulin IPR008266 Tyrosine protein kinase, active site 0.0503676
IPR000217 Tubulin IPR000980 SH2 motif 0.0425012
IPR000217 Tubulin IPR000719 Protein kinase 0.0254403
IPR008280 Tubulin/FtsZ, C-terminal IPR008266 Tyrosine protein kinase, active site 0.0239786
IPR003008 Tubulin/FtsZ, GTPase IPR008266 Tyrosine protein kinase, active site 0.0239786
IPR002452 Alpha tubulin IPR001452 SH3 0.017438
IPR008280 Tubulin/FtsZ, C-terminal IPR000719 Protein kinase 0.0107937
IPR003008 Tubulin/FtsZ, GTPase IPR000719 Protein kinase 0.0107937
IPR008280 Tubulin/FtsZ, C-terminal IPR001245 Tyrosine protein kinase 0.00218747
IPR003008 Tubulin/FtsZ, GTPase IPR001245 Tyrosine protein kinase 0.00218747
IPR000217 Tubulin IPR001245 Tyrosine protein kinase 0.00033966
IPR003008 Tubulin/FtsZ, GTPase IPR001452 SH3 0.000200003
IPR008280 Tubulin/FtsZ, C-terminal IPR001452 SH3 0.000200003

The background colour of the table refers to:

  • Blue Domain is only present in TUBA1
  • Yellow Domain is only present in TEC
  • Green Domain is present in both TUBA1 and TEC

 0.109
Post-translational Modifications

Protein: TUBA1

PTMResidueReference
Acetylation 40 PubMed, HPRD
Deacetylation 40 PubMed, HPRD
Phosphorylation 48 PubMed, HPRD
Phosphorylation 272 PubMed, HPRD
Phosphorylation 432 PubMed, HPRD
Phosphotyrosine 272 HPRD

Protein: TEC

PTMResidueReference
Phosphorylation 206 PubMed, HPRD
Localisation

Protein: TUBA1

LocalisationReference
Cytoplasm HPRD

Protein: TEC

LocalisationReference
Cytoplasm HPRD
Transitive Score

The common interactors between TUBA1 and TEC that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TUBA1 andTEC. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TUBA1 has 1105 interactors and TEC has 1520 interactors of which there are 514 common interactors.

Common InteractorName of Common InteractorScore for TUBA1-Interactor (?)Score for TEC-Interactor (?)
ZAP70 ZAP70: Uncharacterized protein ZAP70 43.20 370.00
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 23.80 0.0308
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 11.90 0.064
XPO1 XPO1, CRM1: Exportin-1 8.55 0.049
CTPS CTPS: CTP synthase 1 8.55 0.049
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 7.26 0.058
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 7.12 0.097
TBCE TBCE: Tubulin-specific chaperone E 5.16 0.049
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 2.32 0.026
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 2.20 0.0308
MDN1 MDN1, KIAA0301: Midasin 2.02 0.049
SOCS7 SOCS7, NAP4, SOCS6: Suppressor of cytokine signaling 7 1.29 0.0258
EEF2 EEF2, EF2: Elongation factor 2 1.26 0.136
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 1.26 0.136
TP73 TP73, P73: Tumor protein p73 1.14 0.081
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.471 0.027
TP53 TP53, P53: Cellular tumor antigen p53 0.426 0.027
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.344 0.041
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.056
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.275 27.80
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.274 0.874
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.274 1.07
H2AFX H2AFX, H2AX: Histone H2A.x 0.254 0.073
CSK CSK: Tyrosine-protein kinase CSK 0.246 1.07
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.233 0.097
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.233 0.110
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.225 0.065
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.225 0.655
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.208 0.064
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.191 0.859
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.191 0.644
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.191 0.731
FNBP1 N/A 0.188 0.110
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.188 0.110
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.181 0.770
LYN LYN: Tyrosine-protein kinase Lyn 0.181 1.20
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.181 0.874
APS SH2B2, APS: SH2B adapter protein 2 0.181 1.78
STAT6 STAT6: Signal transducer and activator of transcription 6 0.181 420.00
CRKL CRKL: Crk-like protein 0.181 1.07
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.874
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.171 0.808
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.166 0.975
SYK SYK: Tyrosine-protein kinase SYK 0.166 0.874
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.163 0.123
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.163 0.191
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.158 0.090
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.156 422.00
STK16 N/A 0.155 0.152
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.049
STAT2 STAT2: Signal transducer and activator of transcription 2 0.152 0.902
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.152 0.065
NCK2 NCK2: Cytoplasmic protein NCK2 0.148 0.874
HCK N/A 0.148 0.770
VAV1 VAV1, VAV: Proto-oncogene vav 0.148 0.874
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.148 46.90
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.148 0.098
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.146 0.097
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.139 0.097
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.139 0.073
RPS6KB1 N/A 0.139 0.110
CXorf9 N/A 0.139 0.136
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.110
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.137 0.100
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.137 0.0308
CDC25C CDC25C: M-phase inducer phosphatase 3 0.137 0.148
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.132 0.152
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.132 0.152
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.127 0.109
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.127 0.110
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.127 0.097
JAK1 0.126 0.770
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.126 1.20
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.126 0.975
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.126 0.975
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.126 1.50
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.124 0.123
YWHAQ YWHAQ: 14-3-3 protein theta 0.124 0.034
CDK7 CDK7, MO15: Cell division protein kinase 7 0.118 0.110
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.118 0.097
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.114 0.110
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.114 0.110
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.113 370.00
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.111 0.0308
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.111 0.136
STAT4 STAT4: Signal transducer and activator of transcription 4 0.110 0.644
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 1.17
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 1.30
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 1.17
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 1.30
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 1.30
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 1.30
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 1.30
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.101 0.110
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.100 0.859
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.100 1.20
MYB MYB: Myb proto-oncogene protein 0.100 0.0263
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.098 1.17
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.098 563.00
STAT3 0.098 1.30
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.577
ROCK1 ROCK1: Rho-associated protein kinase 1 0.0971 0.152
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.096 0.191
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.152
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.096 0.109
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.096 0.026
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.091 0.191
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.090 0.110
LCP1 LCP1, PLS2: Plastin-2 0.090 0.110
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.090 0.097
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.090 0.770
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.090 0.874
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.090 0.770
HIST1H4A HIST1H4A, H4/A, HIST1H4B, H4/I, H4/G, HIST1H4D, H4/B, H4/J, HIST1H4F, HIST4H4, H 0.0898 0.090
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.087 0.034
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.087 0.026
CDK5 CDK5: Cell division protein kinase 5 0.087 0.097
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.087 0.136
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.087 0.097
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.087 0.097
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.087 0.110
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.087 0.088
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.087 0.073
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.087 0.110
CDK4 CDK4: Cell division protein kinase 4 0.087 0.136
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.087 0.097
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.087 0.097
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.086 0.097
LIG4 LIG4: DNA ligase 4 0.086 0.029
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.084 0.055
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.083 0.148
MAPK15 N/A 0.083 0.165
GMIP GMIP: GEM-interacting protein 0.0818 0.110
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.0818 0.110
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.0818 0.097
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.0818 0.110
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.081 0.975
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.081 0.975
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.081 0.874
NRAS HRAS, HRAS1: GTPase HRas precursor 0.081 0.042
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.080 0.109
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.078 0.029
GRLF1 N/A 0.077 0.152
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.077 0.126
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.077 0.110
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.075 0.123
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.075 0.123
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.165
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.098
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.165
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.073 0.694
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.073 0.770
BMX N/A 0.072 1.50
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.071 1.50
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.071 0.110
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.071 0.136
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.071 0.110
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.071 0.110
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.071 0.097
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.071 0.097
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.071 0.123
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.071 0.171
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.071 0.171
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.071 0.097
STK10 STK10: Uncharacterized protein STK10 0.071 0.097
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.071 0.136
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.071 0.136
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.071 0.110
CDK2 CDK2: Cell division protein kinase 2 0.071 0.110
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.071 0.097
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.071 0.577
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.070 0.0453
NPM1 NPM1, NPM: Nucleophosmin 0.070 0.033
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.070 0.081
IRF3 IRF3: Interferon regulatory factor 3 0.070 0.0453
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.070 0.062
SOS1 SOS1: Son of sevenless homolog 1 0.069 0.064
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.069 42.20
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.0688 0.980
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.0688 0.980
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.0688 0.980
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.0688 0.878
CD2AP CD2AP: CD2-associated protein 0.067 0.097
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.067 0.097
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.067 0.110
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.067 0.097
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.065 0.109
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 1.98
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.064 0.775
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.064 1.07
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.041
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.063 0.110
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.062 0.064
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.062 0.098
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.062 0.123
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.062 0.878
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.062 0.878
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.062 0.878
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.062 0.484
GAS2 GAS2: Growth arrest-specific protein 2 0.061 0.039
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.061 0.028
LIMK2 LIMK2: LIM domain kinase 2 0.061 0.123
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.061 0.035
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.060 0.110
WEE1 WEE1: Wee1-like protein kinase 0.060 0.136
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.060 0.123
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.060 0.191
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.060 0.072
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.060 0.152
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.060 0.123
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.0602 0.037
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.057 0.577
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.057 0.577
ALK ALK: ALK tyrosine kinase receptor precursor 0.057 0.445
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.057 0.031
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.057 0.152
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.056 0.225
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.055 0.065
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.054 0.097
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.054 0.049
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.054 0.136
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.054 0.097
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.054 0.088
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.054 0.058
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.054 0.136
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.054 0.136
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.054 0.110
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.054 0.097
ATM ATM: Serine-protein kinase ATM 0.054 0.110
MAPKAPK5 N/A 0.052 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.052 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.052 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.052 0.165
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.052 0.056
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.052 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.052 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.052 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.052 0.165
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.052 0.081
CENPA CENPA: Histone H3-like centromeric protein A 0.052 0.100
PLEK PLEK, P47: Pleckstrin 0.052 0.081
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.052 0.032
ARFGAP1 N/A 0.052 0.037
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.052 0.026
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.026
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.617
GRB10 N/A 0.051 0.617
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.617
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
CRK CRK: Proto-oncogene C-crk 0.051 0.617
UBAP2L N/A 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
MET MET: Hepatocyte growth factor receptor precursor 0.051 0.902
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.051 0.097
YWHAE YWHAE: 14-3-3 protein epsilon 0.051 0.028
AMPH AMPH, AMPH1: Amphiphysin 0.049 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.049 0.165
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.049 0.148
YWHAG YWHAG: 14-3-3 protein gamma 0.049 0.052
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.049 0.165
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.049 0.110
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.049 0.097
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.048 0.152
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.048 0.152
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.048 0.123
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.047 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.047 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.047 0.165
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.047 0.165
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.047 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.047 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.047 0.165
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.047 0.098
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.047 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.047 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.047 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.047 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.047 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.047 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.047 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.047 0.165
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.047 0.098
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.046 0.088
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.046 0.041
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.046 0.056
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.046 0.029
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.046 0.033
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.046 0.033
LIG1 LIG1: DNA ligase 1 0.046 0.033
MYH9 MYH9: Myosin-9 0.046 0.029
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.046 0.026
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.046 0.0308
AIP AIP, XAP2: AH receptor-interacting protein 0.046 0.029
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.033
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.029
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.046 0.097
CCNB1 Cyclin B1 0.046 0.033
CDC20 CDC20: Cell division cycle protein 20 homolog 0.046 0.029
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.046 0.027
FLNA FLNA, FLN, FLN1: Filamin-A 0.046 0.049
FLT4 VEGFR3 long form 0.046 0.553
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.553
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.046 1.13
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.046 1.01
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.046 0.902
SPTAN1 N/A 0.0453 0.098
PHB2 PHB2, BAP, REA: Prohibitin-2 0.0446 0.096
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.0446 0.062
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.088
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.044 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.044 0.148
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.044 0.025
CNN2 CNN2: Calponin-2 0.044 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.044 0.148
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.044 0.148
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.043 0.088
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.043 0.097
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.043 0.136
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.043 0.110
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.043 0.097
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.0425 0.026
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0425 0.123
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.0425 0.0453
TRRAP N/A 0.0425 0.026
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.026
KIF23 N/A 0.0425 0.037
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.0425 0.055
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.0425 0.123
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.0425 0.110
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.041 46.80
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.041 0.088
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.041 0.577
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.041 0.097
STAM2 STAM2: Signal transducing adapter molecule 2 0.041 0.136
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.041 0.088
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.041 0.655
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.041 1.01
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.041 0.808
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.041 0.808
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.731
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.041 0.520
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.520
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.041 0.808
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.04 0.028
MAP2K5 N/A 0.04 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.04 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.04 0.165
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.040 0.056
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.040 0.049
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.040 0.056
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.040 0.069
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.040 0.056
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.040 0.110
MDM4 MDM4, MDMX: Mdm4 protein 0.039 0.037
PRKAA1 N/A 0.039 0.109
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.039 0.191
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.038 0.113
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.033
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.038 0.055
KIF3A KIF3A, KIF3: Kinesin-like protein KIF3A 0.038 0.041
CCNH CCNH: Cyclin-H 0.038 0.029
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.038 0.110
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.038 0.029
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.038 0.088
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.038 0.029
DOK1 DOK1: Docking protein 1 0.038 0.136
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.037 0.032
MCF2 MCF2, DBL: Proto-oncogene DBL 0.037 0.191
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.037 0.808
INSR INSR: Insulin receptor precursor 0.037 0.577
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.037 0.655
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.037 0.808
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.037 0.577
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.036 0.731
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.036 0.055
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.036 0.069
HD HD, IT15: Huntingtin 0.036 0.077
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.036 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.036 0.165
ACTN4 ACTN4: Alpha-actinin-4 0.036 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.036 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.036 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.036 0.148
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.035 0.225
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.035 0.110
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.035 0.088
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.035 46.80
SCML2 SCML2: Sex comb on midleg-like protein 2 0.035 0.072
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.035 0.046
DAPK2 DAPK2: Death-associated protein kinase 2 0.034 0.152
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.034 0.109
CDK6 CDK6: Cell division protein kinase 6 0.034 0.110
AXIN1 0.0333 0.028
ACTN1 ACTN1: Alpha-actinin-1 0.033 0.097
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.033 0.171
SORBS3 SORBS3, SCAM1: Vinexin 0.033 0.136
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.033 277.00
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.033 0.520
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.032 0.037
H1FX H1FX: Histone H1x 0.032 0.032
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.032 0.026
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.032 0.032
ERF ERF: ETS domain-containing transcription factor ERF 0.032 0.037
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.032 0.097
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.032 0.056
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.032 0.110
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.032 0.056
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.032 0.110
MDH2 MDH2: Malate dehydrogenase, mitochondrial precursor 0.032 0.029
FLII FLII, FLIL: Protein flightless-1 homolog 0.032 0.056
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.032 0.049
HSP90AA1 Hsp89-alpha-delta-N 0.032 0.044
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.032 0.049
WASPIP N/A 0.032 0.136
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.032 0.049
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.032 19.00
FYN N/A 0.032 0.174
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.032 0.177
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.032 0.360
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.031 0.136
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.031 108.00
CDKL5 N/A 0.031 0.123
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.031 0.225
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.0308 0.136
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.0308 0.097
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.0308 0.109
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.0308 0.097
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.0308 0.098
DYRK3 N/A 0.0308 0.097
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.0308 0.136
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.029 0.097
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.029 0.171
CNN3 CNN3: Calponin-3 0.029 0.098
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.029 0.049
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.029 0.029
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.029 0.073
PI4KII PI4K2A: Phosphatidylinositol 4-kinase type 2-alpha 0.029 0.029
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.029 0.090
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.029 0.041
RIN3 N/A 0.029 0.177
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.109
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.165
BID BID: BH3-interacting domain death agonist 0.028 0.049
PPEF1 N/A 0.028 0.165
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
HES6 HES6: Transcription cofactor HES-6 0.028 0.049
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.028 0.04
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
PHLDB2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
RAB4A N/A 0.028 0.109
CETN1 CETN1, CEN1, CETN: Centrin-1 0.028 0.098
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.028 0.04
SYTL4 Endocrine transmitter regulatory protein 0.028 0.049
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.028 0.04
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
MYO3A MYO3A: Myosin IIIA 0.028 0.171
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.027 0.098
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.027 0.097
VASP VASP: Vasodilator-stimulated phosphoprotein 0.027 0.123
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.027 0.109
DAPP1 N/A 0.027 0.026
FUBP1 N/A 0.027 0.055
DFFA DFFA, DFF1, H13, DFF45: DNA fragmentation factor subunit alpha 0.027 0.032
CTTN CTTN, EMS1: Src substrate cortactin 0.026 0.109
NFATC1 N/A 0.026 0.046
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.026 0.034
GAB2 N/A 0.026 0.098
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.026 0.026
HMGA2 HMGA2, HMGIC: High mobility group protein HMGI-C 0.026 0.0453
IRS2 IRS2: Insulin receptor substrate 2 0.026 0.098
ETS2 ETS2: Protein C-ets-2 0.026 0.072
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.032
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
PRKCB1 N/A 0.025 0.025
BCOR N/A 0.025 0.025
CCNT2 CCNT2: Cyclin-T2 0.025 0.044
GRK6 N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.025 0.044
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.025 0.098
CAMKK1 N/A 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.075
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.148
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
GIT2 N/A 0.025 0.075
NIPBL N/A 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.148
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.025 0.044
ELMO1 N/A 0.025 0.148
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
CAMK2A N/A 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.148
CREB1 CREB1: cAMP response element-binding protein 0.025 0.044
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.098
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.025 0.044
2.15E-3
Total Score 37.40