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Evidence of Interaction Between PTAFR and GNAO1

The interaction score between PTAFR and GNAO1 is 1.13.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology N/A N/A
Domains Domains present in PTAFR and GNAO1:
Domains in PTAFRDomains in GNAO1
IPR000276 Rhodopsin-like GPCR superfamily
IPR002282 Platelet-activating factor receptor
IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit
IPR001408 G-protein alpha subunit, group I
IPR011025 Transducin, alpha subunit, insertion

The Chi square scores for co-occurrence of domains that are present in PTAFR and GNAO1 are listed below.

Domain 1Domain 2Chi Square
IPR000276 Rhodopsin-like GPCR superfamily IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit 1146.41
IPR000276 Rhodopsin-like GPCR superfamily IPR011025 Transducin, alpha subunit, insertion 1012.26
IPR000276 Rhodopsin-like GPCR superfamily IPR001408 G-protein alpha subunit, group I 485.37

The background colour of the table refers to:

  • Blue Domain is only present in PTAFR
  • Yellow Domain is only present in GNAO1
  • Green Domain is present in both PTAFR and GNAO1

 1.30
Post-translational Modifications

Protein: PTAFR

PTMResidueReference
Disulfide Bridge 173 PubMed, HPRD

Protein: GNAO1

PTMResidueReference
ADP-ribosylarginine 178 PubMed, HPRD
ADP-ribosylcysteine 350 PubMed, HPRD
Localisation

Protein: PTAFR

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD

Protein: GNAO1

LocalisationReference
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PTAFR and GNAO1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PTAFR andGNAO1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PTAFR has 664 interactors and GNAO1 has 1138 interactors of which there are 325 common interactors.

Common InteractorName of Common InteractorScore for PTAFR-Interactor (?)Score for GNAO1-Interactor (?)
GNAI2 Galphai2 protein 1.30 0.714
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 1.30 33.70
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 1.30 0.028
GNA12 GNA12: Guanine nucleotide-binding protein alpha-12 subunit 1.30 0.025
GNAI1 GNAI1: Guanine nucleotide-binding protein G(i), alpha-1 subunit 1.30 1.33
GNA13 GNA13: Guanine nucleotide-binding protein alpha-13 subunit 1.30 0.025
GNAT1 GNAT1, GNATR: Guanine nucleotide-binding protein G(t), alpha-1 subunit 1.30 33.70
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 1.30 33.70
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 1.30 0.714
GNAT2 GNAT2, GNATC: Guanine nucleotide-binding protein G(t), alpha-2 subunit 1.30 33.70
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 1.30 33.70
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 2 1.30 0.028
GNAS GNAS, GNAS1, GSP: Guanine nucleotide-binding protein G(s) subunit alpha isoforms 1.05 0.028
GNA14 GNA14: Guanine nucleotide-binding protein alpha-14 subunit 1.05 33.70
GNAL GNAL: Guanine nucleotide-binding protein G(olf) subunit alpha 1.05 0.028
F10 F10: Coagulation factor X precursor 0.209 0.025
HTR2C HTR2C, HTR1C: 5-hydroxytryptamine receptor 2C 0.165 1.17
FN1 N/A 0.152 0.028
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.109 0.980
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.109 0.980
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.109 0.543
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.109 0.878
C4A C4A: Complement C4-A precursor 0.109 0.0333
RGS16 RGS16, RGSR: Regulator of G-protein signaling 16 0.109 0.980
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.109 0.878
AXIN1 0.109 0.980
RGS4 RGS4: Regulator of G-protein signaling 4 0.109 0.980
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.109 0.878
DRD1 DRD1: D(1A) dopamine receptor 0.083 1.17
F2R F2R, CF2R, PAR1, TR: Proteinase-activated receptor 1 precursor 0.083 1.30
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.083 0.025
TSHR N/A 0.083 1.37
HTR6 HTR6: 5-hydroxytryptamine receptor 6 0.083 1.30
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.083 0.025
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.083 1.30
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.083 1.53
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.083 1.53
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.083 1.30
F2RL3 F2RL3, PAR4: Proteinase-activated receptor 4 precursor 0.083 1.05
MC4R MC4R: Melanocortin receptor 4 0.083 1.30
RHO RHO, OPN2: Rhodopsin 0.083 1.30
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.083 1.30
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.083 0.028
TBXA2R TBXA2R: Thromboxane A2 receptor 0.083 1.05
SSTR3 SSTR3: Somatostatin receptor type 3 0.083 1.17
F2RL2 F2RL2, PAR3: Proteinase-activated receptor 3 precursor 0.083 1.05
OR10H3 OR10H3: Olfactory receptor 10H3 0.083 0.944
TRHR TRHR: Thyrotropin-releasing hormone receptor 0.083 1.17
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.083 1.17
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 1.53
P2RY4 P2RY4, NRU: P2Y purinoceptor 4 0.083 1.30
CCR5 CCR5: CCR5 receptor (Fragment) 0.083 1.53
CHRM2 CHRM2: Muscarinic acetylcholine receptor M2 0.083 1.17
KCNJ1 KCNJ1, ROMK1: ATP-sensitive inward rectifier potassium channel 1 0.083 0.028
TACR2 TACR2, NK2R, NKNAR, TAC2R: Substance-K receptor 0.083 1.17
KCNJ12 KCNJ12, IRK2, KCNJN1: ATP-sensitive inward rectifier potassium channel 12 0.083 0.025
IL8RB IL8RB, CXCR2: High affinity interleukin-8 receptor B 0.083 1.30
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.083 1.17
DRD2 DRD2: D(2) dopamine receptor 0.083 1.30
EDG1 EDG1: Sphingosine 1-phosphate receptor Edg-1 0.083 1.30
FPRL1 FPRL1, FPR2, FPRH1, LXA4R: FMLP-related receptor I 0.083 1.30
HPN HPN, TMPRSS1: Serine protease hepsin 0.083 0.025
FPR1 FPR1: fMet-Leu-Phe receptor 0.083 1.30
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.083 1.30
GPR23 LPA4, GPR23, P2RY9: Lysophosphatidic acid receptor 4 0.083 1.05
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.083 1.30
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.052 0.075
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.052 0.075
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.052 0.075
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.052 0.075
RGS7 RGS7: Regulator of G-protein signaling 7 0.051 0.553
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.049 0.036
NOS1 NOS1: Nitric-oxide synthase, brain 0.049 0.036
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.049 0.036
GRK7 GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor 0.044 0.217
LCP1 LCP1, PLS2: Plastin-2 0.04 0.036
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.04 0.036
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.04 0.044
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.04 0.044
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.04 0.036
OXTR OXTR: Oxytocin receptor 0.034 0.484
BDKRB2 BDKRB2, BKR2: B2 bradykinin receptor 0.034 0.540
AVPR2 AVPR2, ADHR, DIR, DIR3, V2R: Vasopressin V2 receptor 0.034 0.484
AVPR1B AVPR1B, AVPR3, VPR3: Vasopressin V1b receptor 0.034 0.484
AVPR1A AVPR1A, AVPR1: Vasopressin V1a receptor 0.034 0.484
OPRD1 OPRD1, OPRD: Delta-type opioid receptor 0.034 0.484
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.034 0.484
S100A7 S100A7, PSOR1: Protein S100-A7 0.0333 0.04
SERPINF2 SERPINF2, AAP, PLI: Alpha-2-antiplasmin precursor 0.0333 0.0333
MFAP2 MFAP2, MAGP1: Microfibrillar-associated protein 2 precursor 0.0333 0.0333
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.028 0.028
CALCRL CALCRL, CGRPR: Calcitonin gene-related peptide type 1 receptor precursor 0.028 0.025
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.075
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.028 0.028
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.028 0.083
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.028 0.028
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.028 0.028
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.028 0.025
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.028 0.025
GP1BA N/A 0.028 0.209
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.028 0.075
SCTR SCTR: Secretin receptor precursor 0.028 0.025
CD151 CD151, TSPAN24: CD151 antigen 0.028 0.025
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.028 0.028
SLC2A2 SLC2A2, GLUT2: Solute carrier family 2, facilitated glucose transporter member 2 0.028 0.025
F3 F3: Tissue factor precursor 0.028 0.028
KIRREL N/A 0.028 0.025
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.028 0.028
FCGR2A FCGR2A: Fc of IgG, low affinity IIa, receptor 0.028 0.028
CD44 N/A 0.028 0.028
IL7R N/A 0.028 0.028
PTPRA N/A 0.028 0.028
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.028 0.028
PCDH7 N/A 0.028 0.028
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.028 0.148
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.028 0.028
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.028 0.083
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.028 0.025
GABRR1 N/A 0.028 0.028
ITGA3 ITGA3, MSK18: Integrin alpha-3 precursor 0.028 0.025
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.028 0.028
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.028 0.028
PILRA PILRA: Paired immunoglobulin-like type 2 receptor alpha precursor 0.028 0.028
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.028
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.028 0.028
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.028 0.028
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.028 0.028
GRIA2 N/A 0.028 0.028
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.028 0.025
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.028 0.025
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.028 0.025
BTN1A1 N/A 0.028 0.028
AQP4 AQP4: Aquaporin-4 0.028 0.025
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.028 0.028
CD19 N/A 0.028 0.028
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.028 0.028
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.028 0.025
CDH17 CDH17: Cadherin-17 precursor 0.028 0.083
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.028 0.025
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.028 0.028
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.028 0.028
ITGB7 ITGB7: Integrin beta-7 precursor 0.028 0.025
CSF3R N/A 0.028 0.028
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.028 0.025
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.075
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.028 0.025
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.028 0.075
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.028 0.025
INSR INSR: Insulin receptor precursor 0.028 35.90
ASGR1 ASGR1: Asialoglycoprotein receptor 1 0.028 0.025
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.028 0.025
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.028 0.028
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.028 0.028
NULL A1BG: Alpha-1B-glycoprotein precursor 0.028 0.028
ATP4B ATP4B: Potassium-transporting ATPase subunit beta 0.028 0.028
HLA-DRA 0.028 0.028
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.028 0.028
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.028 0.025
SLC7A5 SLC7A5, CD98LC, LAT1, MPE16: Large neutral amino acids transporter small subunit 0.028 0.025
SDC1 SDC1, SDC: Syndecan-1 precursor 0.028 0.028
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.028 0.028
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.028 0.028
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.028
DEAF1 DEAF1: Uncharacterized protein DEAF1 0.028 0.025
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.028 0.028
GPRC5A GPRC5A, GPCR5A, RAI3, RAIG1: Retinoic acid-induced protein 3 0.028 0.165
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.028 0.028
SLC4A1 SLC4A1, AE1, DI, EPB3: Band 3 anion transport protein 0.028 0.025
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.028 0.028
C2orf7 PAP21, C2orf7, UNQ833/PRO1760: Protease-associated domain-containing protein of 0.028 0.025
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.028 0.025
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.025
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.028 0.025
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.028 0.028
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.028 0.028
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.028 0.025
SLC4A4 N/A 0.028 0.028
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.028 0.028
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.083
MET MET: Hepatocyte growth factor receptor precursor 0.028 0.028
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.028 0.028
TFR2 TFR2, hCG_20451: Uncharacterized protein TFR2 0.028 0.028
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.028 0.028
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.028 0.028
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.028 0.028
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.028 0.047
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.028 0.025
PVR PVR, PVS: Poliovirus receptor precursor 0.028 0.028
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.028 0.025
PRLR PRLR: Prolactin receptor precursor 0.028 0.028
NPR3 NPR3, ANPRC: Atrial natriuretic peptide clearance receptor precursor 0.028 0.028
FOLH1 FOLH1, FOLH, NAALAD1, PSM, PSMA: Glutamate carboxypeptidase 2 0.028 0.025
CDH2 CDH2, CDHN, NCAD: Cadherin-2 precursor 0.028 0.083
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.028 0.025
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.028 0.028
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.028 0.028
FGFR2 N/A 0.028 0.025
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.028 0.028
GLRA1 N/A 0.028 0.025
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.028 0.028
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.028 0.025
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.028 0.025
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.028 0.028
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.083
SDC4 SDC4: Syndecan-4 precursor 0.028 0.025
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.028 0.025
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.028 0.028
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.028 0.028
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.028 0.025
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.028 0.025
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.028 0.028
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.028 0.028
TREML1 TREML1, TLT1, UNQ1825/PRO3438: Trem-like transcript 1 protein precursor 0.028 0.028
CD207 CD207, CLEC4K: C-type lectin domain family 4 member K 0.028 0.025
KIT KIT: Mast/stem cell growth factor receptor precursor 0.028 0.025
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.028 0.028
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.028 0.028
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.028 0.028
SELE SELE, ELAM1: E-selectin precursor 0.028 0.028
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.028 0.028
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.028 0.025
CD69 CD69: Early activation antigen CD69 0.028 0.028
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.028
DLG1 N/A 0.028 0.025
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.028 0.075
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.028 0.075
MEP1B MEP1B: Meprin A subunit beta precursor 0.028 0.025
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.028 0.028
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.028 0.028
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.028 0.025
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.028 0.028
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.028 0.025
ITGB1 N/A 0.028 0.028
CDH5 CDH5: Cadherin-5 precursor 0.028 0.083
ABCG2 ABCG2, ABCP, BCRP, BCRP1, MXR: ATP-binding cassette sub-family G member 2 0.028 0.025
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.028 0.028
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.028 0.028
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.028 0.025
UMOD UMOD: Uromodulin precursor 0.028 0.028
KIR3DL1 N/A 0.028 0.028
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.028 0.028
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.028 0.028
PTPNS1 N/A 0.028 0.028
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.028 0.028
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.028 0.028
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.028 0.025
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.025
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.028 0.025
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.028 0.025
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.028 0.028
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.028 0.025
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.028 0.075
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.028 0.025
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.028 0.028
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.028 0.028
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.028 0.075
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.028 0.083
HLA-DQB2 HLA-DQB2, DASS-256O6.1-002, XXbac-BCX231H22.1-002, XXbac-BPG3L13.3-002: Major hi 0.028 0.028
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.028 0.025
GLRB GLRB: Glycine receptor subunit beta precursor 0.028 0.025
GHR GHR: Growth hormone receptor precursor 0.028 0.028
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.028 0.028
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.028 0.025
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.028 0.028
NTRK2 NTRK2, RP11-263K15.1-004, hCG_1985371: Tyrosine-protein kinase receptor 0.028 0.028
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.028 0.028
MPZ MPZ: Myelin P0 protein precursor 0.028 0.028
LAIR1 LAIR1, CD305: Leukocyte-associated immunoglobulin-like receptor 1 precursor 0.028 0.028
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.028 0.025
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.028 0.025
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.028 0.025
EPOR EPOR: Erythropoietin receptor precursor 0.028 0.028
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.028 0.025
FADD FADD, MORT1: Protein FADD 0.028 0.028
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.028 0.028
TPBG TPBG, 5T4: Trophoblast glycoprotein precursor 0.028 0.075
ATRN N/A 0.028 0.025
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.028 0.050
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.028 0.025
ATP2B4 ATP2B4, ATP2B2, MXRA1: Plasma membrane calcium-transporting ATPase 4 0.028 0.028
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.028 0.028
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.028 0.028
TFRC TFRC: Transferrin receptor protein 1 0.028 0.028
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.028 0.083
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.028 0.025
OPTC OPTC, OPT: Opticin precursor 0.028 0.083
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.028 0.025
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.028 0.025
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.028 0.165
MME MME, EPN: Neprilysin 0.028 0.028
GABRB2 N/A 0.028 0.025
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.028 0.028
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.028 0.028
SLC2A1 SLC2A1, GLUT1: Solute carrier family 2, facilitated glucose transporter member 1 0.028 0.025
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.028 0.025
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.028 0.028
SNAP25 N/A 0.028 0.028
DDR2 N/A 0.028 0.025
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.028 0.025
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.028 0.075
DSG2 DSG2: Desmoglein-2 precursor 0.028 0.083
IL9R IL9R: Interleukin-9 receptor precursor 0.028 0.028
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.028 0.025
TLR4 TLR4: Toll-like receptor 4 precursor 0.028 0.075
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.028 0.052
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.028 0.025
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.028 0.025
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.028 0.028
ATP2B1 N/A 0.028 0.028
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.028 0.028
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.028 0.028
ADORA2B ADORA2B: Adenosine receptor A2b 0.027 0.237
HTR1A HTR1A, ADRB2RL1, ADRBRL1: 5-hydroxytryptamine receptor 1A 0.027 0.237
HTR1D HTR1D, HTR1DA, HTRL: 5-hydroxytryptamine receptor 1D 0.027 0.237
ADORA3 ADORA3, UNQ1931/PRO4406: Adenosine A3 receptor 0.027 0.265
HTR5A HTR5A: 5-hydroxytryptamine receptor 5A 0.027 0.265
HTR1B HTR1B, HTR1DB: 5-hydroxytryptamine receptor 1B 0.027 0.237
HTR1F HTR1F, HTR1EL: 5-hydroxytryptamine receptor 1F 0.027 0.265
HTR2B HTR2B: 5-hydroxytryptamine receptor 2B 0.027 0.237
HTR2A HTR2A, HTR2: 5-hydroxytryptamine receptor 2A 0.027 0.237
HTR1E HTR1E: 5-hydroxytryptamine receptor 1E 0.027 0.265
ADORA1 ADORA1: Adenosine receptor A1 0.027 0.237
ADORA2A ADORA2A, ADORA2: Adenosine receptor A2a 0.027 0.237
2.15E-3
Total Score 1.13