PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between CSK and INSR

The interaction score between CSK and INSR is 47.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between CSK and INSR = -0.15

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

1.48E-3

Orthology

Organism	CSK Orthologue		INSR Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
human	IPI00552347	0.145	IPI00027232	0.438
worm	Q9BL77	1	Q968Y9	0.438
fly	Q9VGK8	1	P09208	0.377

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.22E-3

Domains

Domains present in CSK and INSR:

Domains in CSK

Domains in INSR

IPR000719	Protein kinase
IPR001245	Tyrosine protein kinase
IPR008266	Tyrosine protein kinase, active site
IPR011009	Protein kinase-like
IPR001452	SH3
IPR000980	SH2 motif

IPR000494	Epidermal growth-factor receptor (EGFR), L domain
IPR000719	Protein kinase
IPR001245	Tyrosine protein kinase
IPR006211	Furin-like cysteine rich region
IPR006212	Furin-like repeat
IPR008266	Tyrosine protein kinase, active site
IPR003961	Fibronectin, type III
IPR002011	Receptor tyrosine kinase, class II

The Chi square scores for co-occurrence of domains that are present in CSK and INSR are listed below.

Domain 1		Domain 2		Chi Square
IPR000980	SH2 motif	IPR008266	Tyrosine protein kinase, active site	383.26
IPR000980	SH2 motif	IPR001245	Tyrosine protein kinase	238.73
IPR000980	SH2 motif	IPR003961	Fibronectin, type III	184.508
IPR001452	SH3	IPR008266	Tyrosine protein kinase, active site	164.706
IPR001452	SH3	IPR001245	Tyrosine protein kinase	100.857
IPR000980	SH2 motif	IPR000719	Protein kinase	82.1364
IPR000980	SH2 motif	IPR000494	Epidermal growth-factor receptor (EGFR), L domain	46.2087
IPR000980	SH2 motif	IPR006211	Furin-like cysteine rich region	46.2087
IPR000980	SH2 motif	IPR006212	Furin-like repeat	43.075
IPR000719	Protein kinase	IPR000719	Protein kinase	30.6895
IPR001452	SH3	IPR000719	Protein kinase	27.1334
IPR000980	SH2 motif	IPR002011	Receptor tyrosine kinase, class II	24.6768
IPR008266	Tyrosine protein kinase, active site	IPR003961	Fibronectin, type III	22.1621
IPR001452	SH3	IPR003961	Fibronectin, type III	15.104
IPR008266	Tyrosine protein kinase, active site	IPR008266	Tyrosine protein kinase, active site	9.50479
IPR000719	Protein kinase	IPR008266	Tyrosine protein kinase, active site	6.98997
IPR001245	Tyrosine protein kinase	IPR003961	Fibronectin, type III	6.5864
IPR001452	SH3	IPR000494	Epidermal growth-factor receptor (EGFR), L domain	4.57189
IPR001452	SH3	IPR006211	Furin-like cysteine rich region	4.57189
IPR001452	SH3	IPR006212	Furin-like repeat	3.92763
IPR011009	Protein kinase-like	IPR000719	Protein kinase	2.94434
IPR000719	Protein kinase	IPR001245	Tyrosine protein kinase	2.31134
IPR000719	Protein kinase	IPR006212	Furin-like repeat	1.94477
IPR001452	SH3	IPR002011	Receptor tyrosine kinase, class II	1.57489
IPR000719	Protein kinase	IPR000494	Epidermal growth-factor receptor (EGFR), L domain	1.5062
IPR000719	Protein kinase	IPR006211	Furin-like cysteine rich region	1.5062
IPR000719	Protein kinase	IPR002011	Receptor tyrosine kinase, class II	1.16654
IPR001245	Tyrosine protein kinase	IPR008266	Tyrosine protein kinase, active site	0.959759
IPR000719	Protein kinase	IPR003961	Fibronectin, type III	0.712801
IPR011009	Protein kinase-like	IPR003961	Fibronectin, type III	0.616354
IPR001245	Tyrosine protein kinase	IPR002011	Receptor tyrosine kinase, class II	0.432179
IPR011009	Protein kinase-like	IPR002011	Receptor tyrosine kinase, class II	0.315004
IPR008266	Tyrosine protein kinase, active site	IPR000494	Epidermal growth-factor receptor (EGFR), L domain	0.214051
IPR008266	Tyrosine protein kinase, active site	IPR006211	Furin-like cysteine rich region	0.214051
IPR011009	Protein kinase-like	IPR006212	Furin-like repeat	0.180255
IPR011009	Protein kinase-like	IPR001245	Tyrosine protein kinase	0.178275
IPR008266	Tyrosine protein kinase, active site	IPR006212	Furin-like repeat	0.113534
IPR011009	Protein kinase-like	IPR000494	Epidermal growth-factor receptor (EGFR), L domain	0.0778402
IPR011009	Protein kinase-like	IPR006211	Furin-like cysteine rich region	0.0778402
IPR001245	Tyrosine protein kinase	IPR001245	Tyrosine protein kinase	0.0451828
IPR008266	Tyrosine protein kinase, active site	IPR002011	Receptor tyrosine kinase, class II	0.0235657
IPR001245	Tyrosine protein kinase	IPR006212	Furin-like repeat	0.00835708
IPR011009	Protein kinase-like	IPR008266	Tyrosine protein kinase, active site	0.00724826
IPR001245	Tyrosine protein kinase	IPR000494	Epidermal growth-factor receptor (EGFR), L domain	0.000919029
IPR001245	Tyrosine protein kinase	IPR006211	Furin-like cysteine rich region	0.000919029

The background colour of the table refers to:

Blue Domain is only present in CSK
Yellow Domain is only present in INSR
Green Domain is present in both CSK and INSR

0.980

Post-translational Modifications

Protein: CSK

PTM	Residue	Reference
Phosphorylation	184	PubMed, HPRD
Phosphorylation	304	PubMed, HPRD
Phosphorylation	364	PubMed, HPRD
Phosphotyrosine	184	HPRD
Phosphotyrosine	304	PubMed, HPRD

Protein: INSR

PTM	Residue	Reference
Dephosphorylation	999	PubMed, HPRD
Dephosphorylation	1185	PubMed, HPRD
Dephosphorylation	1189	PubMed, HPRD
Dephosphorylation	1190	PubMed, HPRD
Glycosylation	43	PubMed, HPRD
Glycosylation	52	PubMed, HPRD
Glycosylation	105	PubMed, HPRD
Glycosylation	138	PubMed, HPRD
Glycosylation	424	PubMed, HPRD
Glycosylation	445	PubMed, HPRD
Glycosylation	769	PubMed, HPRD
Glycosylation	782	PubMed, HPRD
Glycosylation	920	PubMed, HPRD
Glycosylation	933	PubMed, HPRD
N-linked	541	PubMed, HPRD
Phosphorylation	992	PubMed, HPRD
Phosphorylation	999	PubMed, HPRD
Phosphorylation	1062	PubMed, HPRD
Phosphorylation	1064	PubMed, HPRD
Phosphorylation	1185	PubMed, HPRD
Phosphorylation	1189	PubMed, HPRD
Phosphorylation	1190	PubMed, HPRD
Phosphorylation	1314	PubMed, HPRD
Phosphorylation	1332	PubMed, HPRD
Phosphorylation	1333	PubMed, HPRD
Phosphorylation	1348	PubMed, HPRD
Phosphorylation	1354	PubMed, HPRD
Phosphorylation	1355	PubMed, HPRD
Phosphorylation	1361	PubMed, HPRD
Phosphorylation	1362	PubMed, HPRD
Phosphorylation	1375	PubMed, HPRD
Phosphotyrosine	992	PubMed, HPRD
Phosphotyrosine	999	PubMed, HPRD
Phosphotyrosine	1011	PubMed, HPRD
Phosphotyrosine	1185	PubMed, HPRD
Phosphotyrosine	1189	PubMed, HPRD
Phosphotyrosine	1190	PubMed, HPRD
Phosphotyrosine	1355	PubMed, HPRD
Phosphotyrosine	1361	PubMed, HPRD

Localisation

Protein: CSK

Localisation	Reference
Plasma membrane	HPRD
Cytoplasm	HPRD

Protein: INSR

Localisation	Reference
Nucleus	HPRD
Plasma membrane	HPRD

Transitive Score

The common interactors between CSK and INSR that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CSK andINSR. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CSK has 1875 interactors and INSR has 1177 interactors of which there are 814 common interactors.

Common Interactor	Name of Common Interactor	Score for CSK-Interactor (?)	Score for INSR-Interactor (?)
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	12.80	0.577
STAT6	STAT6: Signal transducer and activator of transcription 6	12.80	0.577
VAV1	VAV1, VAV: Proto-oncogene vav	12.80	0.520
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	6.03	0.577
SYK	SYK: Tyrosine-protein kinase SYK	6.03	0.577
LYN	LYN: Tyrosine-protein kinase Lyn	6.03	0.577
NCK1	NCK1, NCK: Cytoplasmic protein NCK1	6.03	0.586
SH3BP2	SH3BP2: Uncharacterized protein SH3BP2	4.07	0.644
BLNK	BLNK, BASH, SLP65: B-cell linker protein	4.07	0.644
JAK1		3.64	0.520
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	3.64	0.577
SLA	SLA, SLAP, SLAP1: SRC-like-adapter	3.28	0.581
LCP2	LCP2: Lymphocyte cytosolic protein 2	3.05	0.320
APS	SH2B2, APS: SH2B adapter protein 2	2.94	0.577
NCK2	NCK2: Cytoplasmic protein NCK2	2.94	0.520
JAK2	JAK2: Tyrosine-protein kinase JAK2	2.94	277.00
CRKL	CRKL: Crk-like protein	2.94	277.00
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	2.73	0.318
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	2.42	0.581
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	2.20	173.00
HCK	N/A	2.17	0.577
GRAP2	GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2	2.17	0.520
ZAP70	ZAP70: Uncharacterized protein ZAP70	2.17	0.520
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	2.17	277.00
SH2D2A	SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A	1.98	0.644
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	1.98	0.731
STAT2	STAT2: Signal transducer and activator of transcription 2	1.81	0.403
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	1.81	0.065
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	1.81	0.032
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	1.78	0.577
EHD1	EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1	1.62	0.058
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	1.62	0.064
WASPIP	N/A	1.62	0.026
WAS	WAS, IMD2: Wiskott-Aldrich syndrome protein	1.62	0.064
LCP1	LCP1, PLS2: Plastin-2	1.62	0.064
FNBP1	N/A	1.62	0.064
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	1.62	0.064
CXorf9	N/A	1.62	0.058
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	1.50	0.072
PLCG1	PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	1.50	0.581
STAT4	STAT4: Signal transducer and activator of transcription 4	1.33	0.286
CSF1R	CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor	1.33	0.171
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	1.30	0.980
PTPN6	PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6	1.30	0.980
LNK	SH2B3, LNK: SH2B adapter protein 3	1.30	0.980
SLA2	SLA2, C20orf156, SLAP2: Src-like-adapter 2	1.30	0.980
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	1.30	0.980
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	1.20	0.644
SOCS3	SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3	1.20	0.731
PLEK	PLEK, P47: Pleckstrin	1.19	0.045
HLA-C	HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor	1.19	0.098
HLA-G	HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec	1.19	0.098
HLA-A	HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor	1.19	0.109
HLA-B	HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor	1.19	0.098
RASA1	RASA1, RASA: Ras GTPase-activating protein 1	1.17	0.878
STAT3		1.17	0.878
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	1.17	0.098
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	1.17	0.878
GRB2	GRB2, ASH: Growth factor receptor-bound protein 2	1.17	0.878
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	1.17	0.878
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	1.07	0.577
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	1.07	0.041
FLT3	FLT3, STK1: FL cytokine receptor precursor	1.01	0.110
FGFR3	FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor	0.980	0.165
AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor	0.980	0.165
FGFR1	FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor	0.980	0.165
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.964	0.902
EPHA8	EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor	0.878	0.148
EGFR	EGFR, ERBB1: Epidermal growth factor receptor precursor	0.878	0.148
ERBB3	ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor	0.878	0.148
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.878	0.484
RET	RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor	0.878	0.148
RIN1	RIN1: Ras and Rab interactor 1	0.874	0.577
FER	FER, TYK3: Proto-oncogene tyrosine-protein kinase FER	0.874	0.577
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.859	0.644
FYN	N/A	0.824	0.129
PTK2	PTK2, FAK, FAK1: Focal adhesion kinase 1	0.781	0.064
PIK3R2	PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta	0.781	388.00
BMX	N/A	0.775	0.902
INSL3	JAK3: Tyrosine-protein kinase JAK3	0.775	0.644
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	0.770	0.655
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.763	0.058
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.763	0.058
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.763	0.064
SNX17	SNX17, KIAA0064: Sorting nexin-17	0.763	0.064
IQGAP1	IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1	0.763	0.064
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.763	0.058
RIN3	N/A	0.739	0.128
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	0.694	0.577
KIT	KIT: Mast/stem cell growth factor receptor precursor	0.655	0.110
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.655	0.318
EPHA2	EPHA2, ECK: Ephrin type-A receptor 2 precursor	0.655	0.088
FGFR4	FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor	0.655	0.097
MET	MET: Hepatocyte growth factor receptor precursor	0.654	0.123
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.644	0.355
EPHA3	EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor	0.617	0.051
NTRK2	NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor	0.617	0.051
GRB10	N/A	0.617	0.617
CRK	CRK: Proto-oncogene C-crk	0.617	0.617
PTPN11	PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11	0.617	0.617
SHC1	SHC1, SHC, SHCA: SHC-transforming protein 1	0.617	0.617
NTRK1	NTRK1, TRK: High affinity nerve growth factor receptor precursor	0.617	0.051
PTK7	PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor	0.617	0.051
FLT1	FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor	0.586	0.110
PDGFRB	PDGFRB: Beta-type platelet-derived growth factor receptor precursor	0.586	0.136
MST1R	MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor	0.577	0.097
KDR	KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor	0.577	0.136
ERBB2	ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor	0.577	0.110
EPHA1	EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor	0.577	0.097
IGF1R	IGF1R: Insulin-like growth factor 1 receptor precursor	0.577	0.110
HLA-DPB1	HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor	0.561	0.098
CD47	CD47, MER6: Leukocyte surface antigen CD47 precursor	0.561	0.098
CRLF3	N/A	0.561	0.098
ICAM2	ICAM2: Intercellular adhesion molecule 2 precursor	0.561	0.098
HLA-DMA	DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP	0.561	0.109
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.561	0.041
PLCG2	PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2	0.553	0.553
VAV2	VAV2: Uncharacterized protein VAV2	0.553	0.553
TNK2	TNK2, ACK1: Activated CDC42 kinase 1	0.553	0.046
FLT4	VEGFR3 long form	0.553	0.046
EPHB1	EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor	0.520	0.110
EPHA4	EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor	0.520	0.097
EPHB2	EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor	0.520	0.110
EPHB3	EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor	0.520	0.110
EPHA7	EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor	0.520	0.097
EPHB4	EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor	0.520	0.171
TEK	TEK, TIE2: Angiopoietin-1 receptor precursor	0.519	0.191
MERTK	MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor	0.519	0.191
NCF1	Neutrophil cytosolic factor 1 variant (Fragment)	0.515	0.065
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.515	0.072
PSTPIP1	PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1	0.515	0.072
ROCK1	ROCK1: Rho-associated protein kinase 1	0.515	0.065
MATK	DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212	0.491	0.129
SH2D1A	SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A	0.491	0.129
EPHA5	EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor	0.484	0.098
PDGFRA	PDGFRA: Alpha-type platelet-derived growth factor receptor precursor	0.465	0.171
MSN	MSN: Moesin	0.461	0.058
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.461	0.064
ARHGEF6	ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6	0.461	0.058
GMIP	GMIP: GEM-interacting protein	0.461	0.064
PSCD4	PSCD4, CYT4: Cytohesin-4	0.461	0.064
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.461	0.058
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.461	0.064
CD2AP	CD2AP: CD2-associated protein	0.461	0.064
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.461	0.064
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.461	0.029
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.461	0.064
RPS6KB1	N/A	0.461	0.064
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.461	0.064
GRAP	GRAP: GRB2-related adapter protein	0.440	61.50
VAV3	VAV3: Protein vav-3	0.440	0.179
SOCS1	SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1	0.440	0.128
FUBP1	N/A	0.430	0.032
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.416	0.072
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.416	0.072
VASP	VASP: Vasodilator-stimulated phosphoprotein	0.416	0.072
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.416	0.072
ERBB4	ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor	0.415	0.088
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.385	0.026
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.385	0.029
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.385	0.027
ATM	ATM: Serine-protein kinase ATM	0.372	0.026
DOK1	DOK1: Docking protein 1	0.372	0.058
OSBP	OSBP, OSBP1: Oxysterol-binding protein 1	0.372	0.090
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.372	0.026
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.372	0.058
TLN1	TLN1: Uncharacterized protein TLN1	0.372	0.073
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.372	0.058
VIL2	N/A	0.372	0.090
ALK	ALK: ALK tyrosine kinase receptor precursor	0.361	0.064
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.340	0.045
HLA-DMB	HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec	0.340	0.109
MS4A1	MS4A1, CD20: B-lymphocyte antigen CD20	0.340	0.049
CD79A	CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain	0.340	0.098
ICAM3	ICAM3: Intercellular adhesion molecule 3 precursor	0.340	0.098
SORL1	SORL1: Sortilin-related receptor precursor	0.340	0.098
CD22	CD22, SIGLEC2: B-cell receptor CD22 precursor	0.340	0.098
IL10RA	IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor	0.340	0.098
CXCR4	CXCR4: C-X-C chemokine receptor type 4	0.340	0.049
TGFB1	TGFB1, TGFB: Transforming growth factor beta-1 precursor	0.318	0.064
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.307	0.109
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.307	0.081
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.307	0.065
ITGB2	ITGB2, CD18, MFI7: Integrin beta-2 precursor	0.304	0.049
ADAM17	ADAM17, CSVP, TACE: ADAM 17 precursor	0.304	0.049
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.276	0.029
BRAF	BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase	0.275	0.058
EPS15	EPS15, AF1P: Epidermal growth factor receptor substrate 15	0.275	0.065
CAPN2	CAPN2, CANPL2: Calpain-2 catalytic subunit precursor	0.275	0.064
IQSEC1	IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein	0.275	0.058
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.275	0.058
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.275	0.064
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.275	0.064
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.275	0.064
RAPGEF6	RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6	0.275	0.064
LILRB1	N/A	0.274	0.109
CD58	CD58, LFA3: Lymphocyte function-associated antigen 3 precursor	0.274	0.109
IFNGR1	IFNGR1: Interferon-gamma receptor alpha chain precursor	0.274	0.109
SLAMF1	SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor	0.274	0.109
MAG	MAG, GMA: Myelin-associated glycoprotein precursor	0.274	0.098
BRDG1	STAP1, BRDG1: Signal-transducing adaptor protein 1	0.265	0.217
SOCS4	SOCS4, SOCS7: Suppressor of cytokine signaling 4	0.265	0.217
SRMS	SRMS, C20orf148: Tyrosine-protein kinase Srms	0.265	0.265
SH2D1B	SH2D1B, EAT2: SH2 domain-containing protein 1B	0.265	0.217
CISH	CISH, G18: Cytokine-inducible SH2-containing protein	0.265	0.217
CFLAR	CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec	0.260	0.032
STK16	N/A	0.251	0.065
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.251	0.065
S100A9	S100A9, CAGB, CFAG, MRP14: Protein S100-A9	0.251	0.072
CIB1	CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1	0.251	0.065
SOS1	SOS1: Son of sevenless homolog 1	0.246	0.037
PTPN1	PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1	0.246	0.097
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.246	0.046
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.246	0.037
MLH1	MLH1, COCA2: DNA mismatch repair protein Mlh1	0.233	0.026
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	0.233	0.029
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.233	0.026
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.233	0.029
ITGB7	ITGB7: Integrin beta-7 precursor	0.227	0.049
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.227	0.026
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.225	0.064
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.225	0.064
RASA3	RASA3: Ras GTPase-activating protein 3	0.225	0.058
PLCB3	PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	0.225	0.064
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.225	0.065
SH3BP5	N/A	0.225	0.090
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.225	0.064
FGFR2	N/A	0.217	0.027
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.210	0.032
CD4	CD4: T-cell surface glycoprotein CD4 precursor	0.202	0.109
CCR5	CCR5: CCR5 receptor (Fragment)	0.202	0.049
CD7	CD7: T-cell antigen CD7 precursor	0.202	0.098
IL2RB	IL2RB: Interleukin-2 receptor subunit beta precursor	0.202	0.109
CSF2RB	CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor	0.202	0.123
CD2	CD2, SRBC: T-cell surface antigen CD2 precursor	0.202	0.098
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.191	0.072
GAB2	N/A	0.191	0.081
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.188	0.029
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.188	0.029
IMPDH2	IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2	0.188	0.033
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	0.181	0.046
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	0.181	0.041
SOCS2	SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2	0.177	0.145
GRB14	GRB14: Growth factor receptor-bound protein 14	0.176	0.162
SOCS5	SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5	0.174	0.143
LASP1	LASP1, MLN50: LIM and SH3 domain protein 1	0.174	0.072
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.171	0.064
ARHGAP12	ARHGAP12: Rho GTPase-activating protein 12	0.171	0.065
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.171	0.026
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.171	0.113
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.171	0.064
PLD1	PLD1: Phospholipase D1	0.171	0.090
ADAM19	ADAM19, MLTNB, FKSG34: ADAM 19 precursor	0.166	0.109
CD33	CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor	0.166	0.123
SIRPB1	SIRPB1: Signal regulatory protein beta-1 precursor	0.166	0.109
DNM3	DNM3: Uncharacterized protein DNM3	0.165	0.109
PSCD2	N/A	0.165	0.109
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.165	0.049
MAP2K5	N/A	0.165	0.049
S100A16	S100A16, AAG13: Protein S100-A16	0.165	0.109
ITSN1	ITSN1, ITSN, SH3D1A: Intersectin-1	0.165	0.109
AMPH	AMPH, AMPH1: Amphiphysin	0.165	0.109
NF2	NF2, SCH: Merlin	0.165	0.109
PSCD1	PSCD1, D17S811E: Cytohesin-1	0.165	0.109
CNN2	CNN2: Calponin-2	0.165	0.109
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.165	0.049
MAPK15	N/A	0.165	0.109
SNCA	SNCA, NACP, PARK1: Alpha-synuclein	0.165	0.109
ABI1	ABI1, SSH3BP1: Abl interactor 1	0.165	0.109
CAPN3	CAPN3, CANP3, CANPL3, NCL1: Calpain-3	0.165	0.109
PPEF1	N/A	0.165	0.109
CHN1	CHN1, ARHGAP2, CHN: N-chimaerin	0.158	0.115
SHB	SHB: SH2 domain-containing adapter protein B	0.158	0.145
GRB7	GRB7: Growth factor receptor-bound protein 7	0.157	0.200
RPS6KA3	RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3	0.155	0.064
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.155	0.072
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.152	0.081
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.152	0.032
SQSTM1	SQSTM1: Uncharacterized protein SQSTM1	0.152	0.081
IRS2	IRS2: Insulin receptor substrate 2	0.152	0.100
ARHGEF7	N/A	0.148	0.098
NEDD9	NEDD9, CASL: Enhancer of filamentation 1	0.148	0.098
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.148	0.098
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.148	0.098
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.148	0.098
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.148	0.098
KCNIP3	KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin	0.148	0.098
SPTBN1	SPTBN1, SPTB2: Spectrin beta chain, brain 1	0.148	0.098
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.148	0.098
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.148	0.098
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.148	0.098
BIN1	BIN1, AMPHL: Myc box-dependent-interacting protein 1	0.148	0.098
RASGRP2	RASGRP2: RAS guanyl-releasing protein 2	0.148	0.098
ELMO1	N/A	0.148	0.098
AP1GBP1	AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1	0.148	0.098
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.148	0.098
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.148	0.098
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.148	0.098
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.148	0.098
BAIAP2	BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2	0.148	0.098
ACTN4	ACTN4: Alpha-actinin-4	0.148	0.098
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.148	0.098
EEF2K	EEF2K: Elongation factor 2 kinase	0.148	0.098
SH3KBP1	SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1	0.148	0.098
SNX3	N/A	0.148	0.098
EPB41L1	EPB41L1, KIAA0338: Band 4.1-like protein 1	0.148	0.098
RASGRP3	RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3	0.148	0.098
CAMK4	CAMK4: Calcium/calmodulin-dependent protein kinase type IV	0.148	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.148	0.098
EHD4	EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4	0.148	46.90
ITSN2	ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2	0.148	0.098
FLII	FLII, FLIL: Protein flightless-1 homolog	0.146	0.026
CDC37	CDC37: Hsp90 co-chaperone Cdc37	0.144	0.0273
SHC3	SHC3, NSHC, SHCC: SHC-transforming protein 3	0.140	61.50
CHN2	CHN2, ARHGAP3, BCH: Beta-chimaerin	0.140	0.128
CAPNS1	CAPNS1, CAPN4, CAPNS: Calpain small subunit 1	0.140	0.065
AKR7A2	AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2	0.139	0.029
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.139	0.029
CTPS	CTPS: CTP synthase 1	0.139	0.029
CHP	CHP: Calcium-binding protein p22	0.136	0.064
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.136	0.029
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.136	0.073
PRKCQ	PRKCQ, PRKCT: Protein kinase C theta type	0.136	0.044
CALM2	CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca	0.136	0.058
PRKCI	PRKCI, DXS1179E: Protein kinase C iota type	0.136	0.029
STMN1	STMN1, LAP18, OP18: Stathmin	0.136	0.058
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.136	0.054
HPCAL1	HPCAL1, BDR1: Hippocalcin-like protein 1	0.136	0.064
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.136	0.064
DNMBP	DNMBP, KIAA1010: Dynamin-binding protein	0.136	0.073
STAM2	STAM2: Signal transducing adapter molecule 2	0.136	0.073
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.127	0.029
IL12RB2	IL12RB2: Interleukin-12 receptor beta-2 chain precursor	0.126	0.123
CD3E	CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor	0.126	0.098
GHR	GHR: Growth hormone receptor precursor	0.126	0.123
ICOSLG	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor	0.126	0.109
CD3G	CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor	0.126	0.098
F11R	F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor	0.126	0.152
CD3D	CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor	0.126	0.098
CD44	N/A	0.124	0.055
FADD	FADD, MORT1: Protein FADD	0.124	0.055
NEK3	NEK3: Serine/threonine-protein kinase Nek3	0.123	0.072
GAB1	GAB1: GRB2-associated-binding protein 1	0.123	0.081
IRS4	IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4	0.123	0.072
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.123	0.081
GRLF1	N/A	0.123	0.065
HSP90AA1	Hsp89-alpha-delta-N	0.114	0.064
TRAP1	TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor	0.114	0.029
FURIN	FURIN, FUR, PACE, PCSK3: Furin precursor	0.113	0.114
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.113	0.037
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.113	0.041
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.110	0.073
TST	TST: Thiosulfate sulfurtransferase	0.110	0.064
PLD2	PLD2: Phospholipase D2	0.110	0.073
STAM	STAM, STAM1: Signal transducing adapter molecule 1	0.110	0.058
WASL	WASL: Neural Wiskott-Aldrich syndrome protein	0.110	0.073
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.110	0.058
FRS3	FRS3: Fibroblast growth factor receptor substrate 3	0.110	0.058
SNCB	SNCB: Beta-synuclein	0.110	0.065
VSNL1	VSNL1, VISL1: Visinin-like protein 1	0.110	0.072
CNN3	CNN3: Calponin-3	0.110	0.126
SNCG	SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein	0.110	0.072
COBL	N/A	0.110	0.032
NULL	A1BG: Alpha-1B-glycoprotein precursor	0.109	0.165
LAT	LAT: Linker for activation of T-cells family member 1	0.109	0.083
CD79B	CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p	0.109	0.165
PTPRC	PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ	0.109	0.165
TRPV4	TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb	0.109	0.165
CCR2	CCR2, CMKBR2: C-C chemokine receptor type 2	0.109	0.083
CD247	CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor	0.109	0.165
FN1	N/A	0.109	0.165
SIGLEC12	SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12	0.109	0.165
IL6ST	IL6ST: Interleukin-6 receptor subunit beta precursor	0.109	0.165
SIGLEC10	SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor	0.109	0.165
KIR3DL1	N/A	0.109	0.165
PTPRS	PTPRS: Receptor-type tyrosine-protein phosphatase S precursor	0.109	0.165
ADAM15	ADAM15, MDC15: ADAM 15 precursor	0.109	0.165
IL4R	IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor	0.109	0.165
FCGR2B	FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor	0.109	0.165
PTPRE	PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor	0.109	0.165
MDGA1	MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein	0.109	0.165
LEPR	LEPR, DB, OBR: Leptin receptor precursor	0.109	0.165
VCAM1	VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor	0.109	0.165
PVRL1	PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor	0.109	0.165
ADAMTS4	ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor	0.109	0.083
TRPV1	TRPV1: Vanilloid receptor variant TRPV1b	0.109	0.165
NSBP1	NSBP1: Nucleosome-binding protein 1	0.109	0.0688
PTPRR	PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor	0.109	0.165
S100A7	S100A7, PSOR1: Protein S100-A7	0.109	0.072
MCF2	MCF2, DBL: Proto-oncogene DBL	0.109	0.072
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.109	0.081
IRS1	IRS1: Insulin receptor substrate 1	0.109	0.081
ETS2	ETS2: Protein C-ets-2	0.100	0.025
CD28	CD28: T-cell-specific surface glycoprotein CD28 precursor	0.100	0.098
HBEGF	HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con	0.100	0.109
ICAM1	ICAM1: Intercellular adhesion molecule 1 precursor	0.100	0.109
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.100	0.109
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.100	0.051
IFNAR1	IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor	0.100	0.123
GPA33	GPA33: Cell surface A33 antigen precursor	0.100	0.109
CD80	CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor	0.100	0.123
PRKCE	PRKCE, PKCE: Protein kinase C epsilon type	0.099	15.80
SNTA1	SNTA1, SNT1: Alpha-1-syntrophin	0.099	0.058
EPB41L2	EPB41L2: Band 4.1-like protein 2	0.099	0.058
ROCK2	ROCK2, KIAA0619: Rho-associated protein kinase 2	0.099	0.064
EPB41L3	EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3	0.099	0.064
PAK7	PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7	0.099	0.029
TAGLN	TAGLN, SM22, WS3-10: Transgelin	0.099	0.073
PAK6	PAK6, PAK5: Serine/threonine-protein kinase PAK 6	0.099	0.029
S100A3	S100A3, S100E: Protein S100-A3	0.098	0.081
SPTAN1	N/A	0.098	0.065
S100B	S100B: Protein S100-B	0.098	0.072
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.098	0.062
ACVR1B	ACVR1B, ACVRLK4: Activin receptor type-1B precursor	0.098	0.025
LETM1	LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial	0.098	0.062
CETN1	CETN1, CEN1, CETN: Centrin-1	0.098	0.062
CNTN4	CNTN4: Contactin-4 precursor	0.098	0.148
BSG	N/A	0.098	0.148
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.098	0.062
TRPM7	TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me	0.098	0.148
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.098	0.030
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.098	0.030
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.098	0.062
PTPN2	PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2	0.098	71.20
CNTN1	CNTN1: Contactin-1 precursor	0.098	0.148
PTPRF	PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor	0.098	0.148
L1CAM	L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor	0.098	0.148
TRPV6	TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6	0.098	0.075
ADAM33	ADAM33, UNQ873/PRO1891: ADAM 33 precursor	0.098	0.148
MYL4	MYL4, MLC1, PRO1957: Myosin light polypeptide 4	0.097	0.064
TTN	N/A	0.097	0.064
KIAA1967	KIAA1967, DBC1: Protein KIAA1967	0.097	0.090
SORBS3	SORBS3, SCAM1: Vinexin	0.097	0.064
ACTN1	ACTN1: Alpha-actinin-1	0.097	0.058
PAK4	PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4	0.097	0.033
DAB2	DAB2, DOC2: Disabled homolog 2	0.097	0.181
PSD	TYL: TYL protein	0.097	0.058
PRKCA	PRKCA, PKCA, PRKACA: Protein kinase C alpha type	0.097	0.058
MYL3	MYL3: Myosin light polypeptide 3	0.097	0.064
PRKCG	PRKCG, PKCG: Protein kinase C gamma type	0.097	0.029
PECAM1	PECAM1: Platelet endothelial cell adhesion molecule precursor	0.0955	0.038
CD82	CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen	0.090	0.056
ROBO1	ROBO1, DUTT1: Roundabout homolog 1 precursor	0.090	0.097
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.090	0.037
STMN2	STMN2, SCG10, SCGN10: Stathmin-2	0.088	0.064
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.088	0.073
HPCA	HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin	0.088	0.064
PRKCZ	PRKCZ, PKC2: Protein kinase C zeta type	0.088	0.064
LIMK1	LIMK1, LIMK: LIM domain kinase 1	0.088	0.064
EPS15L1	EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1	0.088	0.058
MAP3K10	MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10	0.088	0.064
MYL9	MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform	0.088	0.073
RDX	RDX: Radixin	0.088	0.073
CNKSR2	CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2	0.088	0.058
HSPB8	HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8	0.088	0.041
DAB1	DAB1: Disabled homolog 1	0.088	0.073
EHD2	EHD2, PAST2: EH domain-containing protein 2	0.088	0.064
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.087	0.032
CIITA	CIITA, MHC2TA: MHC class II transactivator	0.087	0.0263
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.087	0.096
FABP5	FABP5: Fatty acid-binding protein, epidermal	0.086	0.029
TBC1D1	TBC1D1, KIAA1108: TBC1 domain family member 1	0.086	0.034
CASP8	CASP8, MCH5: Caspase-8 precursor	0.083	0.049
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.083	0.04
AKAP12	AKAP12, AKAP250: A-kinase anchor protein 12	0.083	0.049
HNRPK	HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K	0.083	0.04
ADRB2	ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor	0.0818	0.044
ADAMDEC1	ADAMDEC1: ADAM DEC1 precursor	0.081	0.049
ICAM5	ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor	0.081	0.109
IL9R	IL9R: Interleukin-9 receptor precursor	0.081	0.098
MPZL1	MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor	0.081	0.109
MPL	MPL, TPOR: Thrombopoietin receptor precursor	0.081	0.123
FASLG	FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6	0.081	0.055
CD5	CD5, LEU1: T-cell surface glycoprotein CD5 precursor	0.081	0.049
CSPG2	N/A	0.0794	0.081
FGF23	FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor	0.0794	0.072
MAPK8IP1	MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1	0.078	0.064
PRKD1	PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1	0.078	0.097
PLCB1	PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-	0.078	0.058
TLN2	TLN2: Uncharacterized protein TLN2	0.078	0.064
CTTN	CTTN, EMS1: Src substrate cortactin	0.078	0.100
YWHAB	YWHAB: 14-3-3 protein beta/alpha	0.078	12.50
YWHAZ	YWHAZ: 14-3-3 protein zeta/delta	0.078	0.026
B2M	B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro	0.076	0.029
TSC2	TSC2, TSC4: Tuberin	0.075	0.044
PARD6A	PARD6A, PAR6A: Partitioning defective 6 homolog alpha	0.075	0.044
GART	GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include	0.075	0.044
KCNAB2	KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2	0.075	0.044
PRKD3	PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3	0.074	6.81
ITGAE	ITGAE: Integrin alpha-E precursor	0.074	0.056
ITGA4	ITGA4, CD49D: Integrin alpha-4 precursor	0.074	0.049
CXADR	CXADR, CAR: Coxsackievirus and adenovirus receptor precursor	0.0727	0.109
LILRB5	LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur	0.0727	0.123
SCML2	SCML2: Sex comb on midleg-like protein 2	0.0727	0.025
DUSP3	DUSP3, VHR: Dual specificity protein phosphatase 3	0.0727	0.063
BCAM	BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor	0.0727	0.152
CEACAM1	CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr	0.072	0.123
PTPRJ	PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor	0.072	0.123
ALCAM	ALCAM, MEMD: CD166 antigen precursor	0.072	0.098
IL1RL1	IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor	0.072	0.307
TRPC3	N-terminally extended type 3 canonical transient receptor potential channel	0.072	0.055
TP73	TP73, P73: Tumor protein p73	0.072	0.063
BTC	BTC: Probetacellulin precursor [Contains: Betacellulin	0.072	0.123
EPOR	EPOR: Erythropoietin receptor precursor	0.072	0.123
ROBO4	ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor	0.072	0.123
CD1A	CD1A: T-cell surface glycoprotein CD1a precursor	0.072	0.109
SEL1L	SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor	0.070	0.053
FREQ	FREQ, FLUP, NCS1: Neuronal calcium sensor 1	0.070	0.064
PITPNM1	PITPNM1: Uncharacterized protein PITPNM1	0.069	0.033
HDLBP	HDLBP, HBP, VGL: Vigilin	0.069	0.033
SIPA1L1	SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein	0.069	0.026
JUP	JUP, CTNNG, DP3: Junction plakoglobin	0.069	0.033
AZGP1	AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding	0.0688	0.109
IL6R	IL6R: Interleukin-6 receptor alpha chain precursor	0.0688	0.109
SLC4A7	SLC4A7: Uncharacterized protein SLC4A7	0.067	0.028
GNAI3	GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha	0.066	56.70
NEO1	NEO1, NGN: Neogenin precursor	0.065	0.088
TUBB2A	TUBB2A, TUBB2: Tubulin beta-2A chain	0.065	0.041
PTPRB	PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor	0.065	0.110
TGFA	TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow	0.065	0.098
HAVCR1	HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor	0.065	0.109
ITGB4	N/A	0.065	0.123
NCAM1	NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor	0.065	0.109
F3	F3: Tissue factor precursor	0.065	0.123
PVR	PVR, PVS: Poliovirus receptor precursor	0.065	0.109
EGF	EGF: Pro-epidermal growth factor precursor	0.065	0.123
PIGR	PIGR: Polymeric-immunoglobulin receptor precursor	0.065	0.123
PRLR	PRLR: Prolactin receptor precursor	0.065	0.152
TUBB3	TUBB3, TUBB4: Tubulin beta-3 chain	0.065	0.041
TIAM1	TIAM1: T-lymphoma invasion and metastasis-inducing protein 1	0.064	0.041
MIP	MIP, AQP0: Lens fiber major intrinsic protein	0.064	0.035
DCC	DCC: Netrin receptor DCC precursor	0.064	0.097
CENTA1	CENTA1: Centaurin-alpha 1	0.063	0.041
IL12B	IL12B, NKSF2: Interleukin-12 subunit beta precursor	0.063	0.081
MDN1	MDN1, KIAA0301: Midasin	0.063	0.026
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.063	0.029
BCAN	BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor	0.062	0.098
PTPRG	PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor	0.058	0.136
TNC	TNC, HXB: Tenascin precursor	0.058	0.097
PTPRZ1	N/A	0.058	0.088
CNTN2	CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor	0.058	0.088
APBA2	APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2	0.058	0.037
NPR1	NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor	0.058	0.136
ADAM23	ADAM23, MDC3: ADAM 23 precursor	0.058	0.098
LIFR	LIFR: Leukemia inhibitory factor receptor precursor	0.058	0.191
THY1	THY1: Thy-1 membrane glycoprotein precursor	0.058	0.109
JAM2	JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor	0.058	0.152
ARHGEF12	ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12	0.058	0.063
TNFRSF1A	TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre	0.057	0.062
HSP90B1	HSP90B1, TRA1: Endoplasmin precursor	0.056	0.064
TAOK1	TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1	0.053	0.0273
TBC1D2	TBC1D2, PARIS1: TBC1 domain family member 2	0.053	0.030
KRT6E	KRT6C, KRT6E: Keratin, type II cytoskeletal 6C	0.052	0.049
SCRIB	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4	0.052	0.029
FLNA	FLNA, FLN, FLN1: Filamin-A	0.052	0.032
NCAM2	NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor	0.052	0.088
PTPRM	PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor	0.052	0.097
IGHG1	N/A	0.051	0.051
FCGR2A	FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region	0.051	0.051
C9orf88	N/A	0.051	0.051
UNC5D	UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor	0.051	0.051
NULL	Ig lambda chain V-II region NEI	0.051	0.051
HLA-A	N/A	0.051	0.051
HLA-A	HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor	0.051	0.051
FN1	FN1, FN: Fibronectin precursor	0.051	0.051
UBAP2L	N/A	0.051	0.051
SPARCL1	SPARCL1: SPARC-like protein 1 precursor	0.051	0.051
IGHE	IGHE: Ig epsilon chain C region	0.051	0.051
DOK2	DOK2: Docking protein 2	0.051	0.051
SNX2	SNX2, TRG9: Sorting nexin-2	0.051	0.051
MYLK	MYLK, MLCK: Myosin light chain kinase, smooth muscle	0.051	0.051
C6orf21	LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G	0.051	0.051
HLA-DRA	HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu	0.051	0.051
NULL	Ig lambda chain V-I region EPS	0.051	0.051
ITIH3	ITIH3: Inter-alpha-trypsin inhibitor heavy chain H3 precursor	0.051	0.051
PTPNS1	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec	0.051	0.051
KIRREL	KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor	0.051	0.051
BCR	BCR, BCR1, D22S11: Breakpoint cluster region protein	0.051	0.051
NULL	Ig heavy chain V-III region WEA	0.051	0.051
TRB@	TCRB: T-cell receptor beta chain V region CTL-L17 precursor	0.051	0.051
MARK1	MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1	0.051	0.051
NULL	Ig kappa chain V region EV15 precursor	0.051	0.051
EVL	EVL, RNB6: Ena/VASP-like protein	0.051	0.051
SNX12	N/A	0.051	0.051
LOC649805	Ig heavy chain V-II region COR	0.051	0.051
DNM2	DNM2, DYN2: Dynamin-2	0.051	0.051
MARK2	N/A	0.051	0.051
NULL	Ig heavy chain V-III region BUR	0.051	0.051
HLA-DRB2	HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment)	0.051	0.051
HLA-B	HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor	0.051	0.051
NULL	TCRA: T-cell receptor alpha chain V region CTL-L17 precursor	0.051	0.051
COL6A3	COL6A3: Collagen alpha-3(VI) chain precursor	0.051	0.051
MAP3K9	MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9	0.051	0.051
NCAM1	N/A	0.051	0.051
HLA-DQB1	HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso	0.051	0.051
IGHM	N/A	0.051	0.051
KIAA1688	KIAA1688: KIAA1688 protein (Fragment)	0.051	0.051
NRCAM	NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor	0.051	0.051
IGHD	N/A	0.051	0.051
IGHA2	IGHA2: Ig alpha-2 chain C region	0.051	0.051
DNM1	DNM1, DNM: Dynamin-1	0.051	0.051
DLG1	DLG1: Disks large homolog 1	0.051	0.051
IGHG3	N/A	0.051	0.051
PPP1R14C	PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C	0.051	0.051
PTPRA	N/A	0.051	0.051
CDC42BPA	CDC42BPA: Serine/threonine-protein kinase MRCK alpha	0.051	0.051
IGHA1	N/A	0.051	0.051
KIAA1914	AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2	0.051	0.051
PPP1R1B	PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B	0.051	0.051
IFNAR2	IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor	0.051	0.051
RAPH1	N/A	0.051	0.051
NULL	Ig kappa chain V-I region CAR	0.051	0.051
PAPPA	PAPPA: Pappalysin-1 precursor	0.051	0.051
TJP2	TJP2, X104, ZO2: Tight junction protein ZO-2	0.051	0.051
STIM1	STIM1, GOK: Stromal interaction molecule 1 precursor	0.051	0.051
DBNL	DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein	0.051	0.051
F5	F5: Coagulation factor V precursor	0.051	0.100
IL1B	IL1B, IL1F2: Interleukin-1 beta precursor	0.051	0.072
IL18	IL18, IGIF, IL1F4: Interleukin-18 precursor	0.051	0.072
PTP4A3	PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3	0.050	0.040
PEA15	PEA15: Astrocytic phosphoprotein PEA-15	0.049	0.032
PLAUR	PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor	0.049	0.083
EMR2	EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor	0.049	0.165
EDAR	EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor	0.049	0.052
TNFSF13B	TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto	0.049	0.028
SEMA4B	SEMA4B: Sema domain, immunoglobulin domain	0.049	0.083
EDA	N/A	0.049	0.083
TNFSF14	TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m	0.049	0.028
LSP1	LSP1, WP34: Lymphocyte-specific protein 1	0.049	0.083
TNFSF12	TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf	0.049	0.028
GPR126	DREG: Developmentally regulated G-protein-coupled receptor alpha 1	0.049	0.028
SVIL	SVIL: Supervillin	0.047	0.036
CFL2	CFL2: Cofilin-2	0.047	0.036
GSN	GSN: Gelsolin precursor	0.047	0.036
COTL1	COTL1, CLP: Coactosin-like protein	0.047	0.036
ANXA1	ANXA1, ANX1, LPC1: Annexin A1	0.046	0.039
MLLT4	N/A	0.046	0.046
TBC1D4	TBC1D4: TBC1D4 protein	0.046	0.046
EPB41	EPB41, E41P: Protein 4.1	0.046	0.046
AGC1	AGC1, CSPG1, MSK16: Aggrecan core protein precursor	0.046	0.046
BCAR1	BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1	0.046	0.046
PPP1R14A	PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A	0.046	0.046
NF1	NF1: Neurofibromin	0.046	0.046
KIF1B	KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B	0.046	0.046
PHLDB2	PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2	0.046	0.046
CNTN3	CNTN3, KIAA1496, PANG: Contactin-3 precursor	0.046	0.046
MAPK14	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14	0.046	0.046
SYNGAP1	SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP	0.046	0.046
LRIG2	LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot	0.046	0.046
PHC3	PHC3, EDR3, PH3: Polyhomeotic-like protein 3	0.046	0.046
LMO7	N/A	0.046	0.046
PTP4A1	PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1	0.046	0.060
THBS3	THBS3, TSP3: Thrombospondin-3 precursor	0.046	0.064
FGL2	FGL2: Fibroleukin precursor	0.046	0.064
CD6	CD6: T-cell differentiation antigen CD6 precursor	0.046	0.026
IGFBP4	IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor	0.046	0.057
TNXB	TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor	0.046	0.126
CP	CP: Ceruloplasmin precursor	0.046	0.100
ADAMTS1	ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor	0.046	0.091
PLXND1	PLXND1, KIAA0620: Plexin-D1 precursor	0.0453	0.077
FSHB	FSHB: Follitropin subunit beta precursor	0.045	0.081
GDF15	GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor	0.045	0.202
LHB	LHB: Lutropin subunit beta precursor	0.045	0.081
IGFBP1	IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor	0.045	0.091
CGB	CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor	0.045	0.202
CEACAM6	CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso	0.045	0.081
IL1A	IL1A, IL1F1: Interleukin-1 alpha precursor	0.045	0.072
CGA	CGA: Glycoprotein hormones alpha chain precursor	0.045	0.126
ST8SIA4	ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe	0.0446	0.045
SELL	SELL, LNHR, LYAM1: L-selectin precursor	0.0446	0.109
CD69	CD69: Early activation antigen CD69	0.0446	0.049
FABP4	FABP4: Fatty acid-binding protein, adipocyte	0.044	0.033
FABP3	FABP3, FABP11, MDGI: Fatty acid-binding protein, heart	0.044	0.029
PMP2	PMP2: Myelin P2 protein	0.044	0.029
GRIA3	GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor	0.044	0.047
ATP1A1	ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor	0.044	0.075
ADCY6	ADCY6, KIAA0422: Adenylate cyclase type 6	0.044	0.025
CREB1	CREB1: cAMP response element-binding protein	0.044	0.030
ATRN	N/A	0.044	0.148
GGA3	GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3	0.044	0.030
STOM	STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein	0.044	0.025
ATP2A2	ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0.044	0.075
YWHAQ	YWHAQ: 14-3-3 protein theta	0.0425	0.029
TNN	TNN: Tenascin-N precursor	0.042	0.030
SPARC	SPARC, ON: SPARC precursor	0.041	0.064
FGF9	FGF9: Glia-activating factor precursor	0.041	0.073
EFNB2	EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor	0.041	0.073
KAL1	KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor	0.041	0.064
DLG2	DLG2: Disks large homolog 2	0.041	0.090
GAD2	GAD2, GAD65: Glutamate decarboxylase 2	0.041	0.058
FKBP9	FKBP9, FKBP60, FKBP63: FK506-binding protein 9 precursor	0.041	0.046
RYR2	RYR2: Ryanodine receptor 2	0.041	0.041
IGFBP3	IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor	0.041	0.075
IGFBP7	IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor	0.041	0.072
FGF5	FGF5: Fibroblast growth factor 5 precursor	0.041	0.081
FSTL1	FSTL1, FRP: Follistatin-related protein 1 precursor	0.041	0.100
INHA	INHA: Inhibin alpha chain precursor	0.041	0.100
COL7A1	COL7A1: Collagen alpha-1(VII) chain precursor	0.041	0.072
TSHB	TSHB: Thyrotropin subunit beta precursor	0.041	0.081
CD36	CD36, GP3B, GP4: Platelet glycoprotein 4	0.041	0.056
ITGB3	ITGB3, GP3A: Integrin beta-3 precursor	0.041	0.069
EFNB1	EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor	0.041	0.073
BMP7	BMP7, OP1: Bone morphogenetic protein 7 precursor	0.041	0.073
HAPLN1	HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor	0.041	0.064
SLC4A3	SLC4A3, AE3: Anion exchange protein 3	0.04	0.052
TBXA2R	TBXA2R: Thromboxane A2 receptor	0.04	0.028
GNAI2	Galphai2 protein	0.040	0.049
ST6GAL1	ST6GAL1, SIAT1: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltrans	0.040	0.037
DBN1	DBN1, D0S117E: Drebrin	0.039	0.027
MAPRE2	MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2	0.038	0.026
MT3	MT3: Metallothionein-3	0.037	0.049
ANXA2	ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2	0.037	0.034
CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi	0.037	0.025
ATP2B1	N/A	0.037	0.049
ATP4A	ATP4A: Potassium-transporting ATPase alpha chain 1	0.037	0.077
TNNC1	TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles	0.037	0.072
TNNC2	TNNC2: Troponin C, skeletal muscle	0.037	0.029
LAMB1	LAMB1: Laminin subunit beta-1 precursor	0.037	0.073
VWF	VWF, F8VWF: von Willebrand factor precursor	0.037	0.090
FKBP10	FKBP10, FKBP65, PSEC0056: FK506-binding protein 10 precursor	0.037	0.041
HSPG2	HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec	0.037	0.073
LAMC1	LAMC1, LAMB2: Laminin subunit gamma-1 precursor	0.037	0.073
RYR1		0.037	0.041
PDGFA	PDGFA, PDGF1: Platelet-derived growth factor A chain precursor	0.036	0.100
NDP	NDP: Norrin precursor	0.036	0.081
IGFBP6	IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor	0.036	0.032
F8	F8, F8C: Coagulation factor VIII precursor	0.036	0.072
IGFBP5	IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor	0.036	0.091
AQP4	AQP4: Aquaporin-4	0.036	0.047
VIL1	VIL1, VIL: Villin-1	0.035	0.027
AQP2	AQP2: Aquaporin-2	0.035	0.027
KRT1	KRT1, KRTA: Keratin, type II cytoskeletal 1	0.034	0.032
SPOCK2	SPOCK2, KIAA0275, UNQ269/PRO306, TICN2: Testican-2 precursor	0.034	0.0273
CAV2	CAV2: Caveolin-2	0.034	0.0338
GJA1	GJA1, GJAL: Gap junction alpha-1 protein	0.034	0.0338
GJB1	GJB1, CX32: Gap junction beta-1 protein	0.0338	0.038
PVALB	PVALB: Parvalbumin alpha	0.033	0.029
PLXNB1	PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor	0.033	0.062
GABRR1	N/A	0.033	0.062
RAP1GA1	N/A	0.033	0.025
SDC1	SDC1, SDC: Syndecan-1 precursor	0.032	0.080
UNC84B	UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2	0.032	0.044
CTLA4	CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor	0.030	0.038
CNN1	CNN1: Calponin-1	0.030	0.0338
PPP1R1A	PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A	0.030	0.0338
GJA5	GJA5: Gap junction alpha-5 protein	0.030	0.0782
FRS2	FRS2: Fibroblast growth factor receptor substrate 2	0.030	0.034
CHAT	CHAT: Choline O-acetyltransferase	0.030	0.030
FCN3	FCN3, FCNH, HAKA1: Ficolin-3 precursor	0.030	0.086
ANGPTL6	AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor	0.030	0.098
C1QBP	C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot	0.030	0.030
FGG	FGG, PRO2061: Fibrinogen gamma chain precursor	0.030	0.098
GLRB	GLRB: Glycine receptor subunit beta precursor	0.029	0.028
GABRB1	GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor	0.029	0.049
SDC4	SDC4: Syndecan-4 precursor	0.029	0.035
GRIA1	GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor	0.029	0.0308
NGFR	NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor	0.029	0.062
TOM1L1	TOM1L1, SRCASM: TOM1-like protein 1	0.029	0.025
AGTR1	AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor	0.029	0.127
CD59	CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor	0.029	0.096
LYPD3	LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor	0.029	0.062
RHO	RHO, OPN2: Rhodopsin	0.029	0.062
TMPRSS2	TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor	0.029	0.056
GRIA4	GRIA4, GLUR4: Glutamate receptor 4 precursor	0.029	0.035
GRIK2	GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor	0.029	0.0308
TSHR	N/A	0.029	0.0308
HPN	HPN, TMPRSS1: Serine protease hepsin	0.029	0.056
GLRA1	N/A	0.029	0.056
MICAL-L1	MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1	0.029	0.041
INPP5D	N/A	0.0288	0.0288
TENC1	N/A	0.0288	0.0288
BTK	N/A	0.0288	0.0288
FES	Proto-oncogene c-fes variant 4	0.0288	0.0288
BTK	N/A	0.0288	0.0288
FES	Proto-oncogene c-fes variant 3	0.0288	0.0288
BTK	BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros	0.0288	0.0288
BLNK	BLNK, SLP65, BASH: B-cell linker protein (Fragment)	0.0288	0.0288
BTK	N/A	0.0288	0.0288
BLK	BLK: Tyrosine-protein kinase BLK	0.0288	0.0288
TNS1	TNS1, TNS: Tensin-1	0.0288	0.0288
FES	FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps	0.0288	0.0288
PIK3R1	PIK3R1, GRB1: Phosphatidylinositol 3-kinase regulatory subunit alpha	0.0288	0.0288
DAPP1	DAPP1, BAM32, HSPC066: Dual adapter for phosphotyrosine and 3-phosphotyrosine an	0.0288	0.0288
SYK	N/A	0.0288	0.0288
BLNK	N/A	0.0288	0.0288
BLNK	N/A	0.0288	0.0288
SOCS6	SOCS6, CIS4, SOCS4: Suppressor of cytokine signaling 6	0.0288	0.0288
FGR	FGR, RP1-159A19.2-007: Gardner-Rasheed feline sarcoma viral (Fragment)	0.0288	0.0288
VAV3	VAV-like protein (Fragment)	0.0288	0.0288
BLNK	N/A	0.0288	0.0288
PIK3R3	PIK3R3: Phosphatidylinositol 3-kinase regulatory subunit gamma	0.0288	0.0288
GRB10	Adapter protein (Fragment)	0.0288	0.0288
BTK	N/A	0.0288	0.0288
YWHAG	YWHAG: 14-3-3 protein gamma	0.028	0.049
UACA	UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats	0.028	0.028
AQP1	AQP1, CHIP28: Aquaporin-1	0.028	0.027
PPP1R14D	PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D	0.0273	0.030
PEBP1	PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1	0.0273	0.034
CAV1	CAV1, CAV: Caveolin-1	0.0273	0.034
GPR116	GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor	0.027	0.047
MPP4	MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4	0.027	0.027
PTPRN2	PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor	0.027	0.027
NAGPA	NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur	0.027	0.098
ANXA9	ANXA9, ANX31: Annexin A9	0.0263	0.039
GRIN1	GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor	0.026	0.0308
SCARB2	SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2	0.026	0.056
INPPL1	INPPL1, SHIP2: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2	0.0258	0.0258
FES	N/A	0.0258	0.0258
SOCS7	SOCS7, NAP4, SOCS6: Suppressor of cytokine signaling 7	0.0258	0.0258
SHC2	N/A	0.0258	12.40
GAS2	GAS2: Growth arrest-specific protein 2	0.026	0.037
RSU1	RSU1, RSP1: Ras suppressor protein 1	0.025	0.044
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.036
LRRC7	LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7	0.025	0.044

0.228

Total Score

47.30