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Evidence of Interaction Between TLR2 and CD14

The interaction score between TLR2 and CD14 is 1.57.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TLR2 and CD14 = 0.87

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.027
Orthology N/A N/A
Domains Domains present in TLR2 and CD14:
Domains in TLR2Domains in CD14
IPR000157 TIR
IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR002086 Aldehyde dehydrogenase
IPR003591 Leucine-rich repeat, typical subtype
IPR004075 Interleukin-1 receptor, type I/Toll precursor
IPR001611 Leucine-rich repeat

The Chi square scores for co-occurrence of domains that are present in TLR2 and CD14 are listed below.

Domain 1Domain 2Chi Square
IPR000483 Cysteine-rich flanking region, C-terminal IPR001611 Leucine-rich repeat 133.077
IPR004075 Interleukin-1 receptor, type I/Toll precursor IPR001611 Leucine-rich repeat 118.475
IPR000157 TIR IPR001611 Leucine-rich repeat 116.576
IPR001611 Leucine-rich repeat IPR001611 Leucine-rich repeat 102.545
IPR003591 Leucine-rich repeat, typical subtype IPR001611 Leucine-rich repeat 80.5457
IPR002086 Aldehyde dehydrogenase IPR001611 Leucine-rich repeat 6.50235

The background colour of the table refers to:

  • Blue Domain is only present in TLR2
  • Yellow Domain is only present in CD14
  • Green Domain is present in both TLR2 and CD14

 0.165
Post-translational Modifications

Protein: TLR2

PTMResidueReference
N-linked 114 PubMed, HPRD
N-linked 199 PubMed, HPRD
N-linked 442 PubMed, HPRD

Protein: CD14

PTMResidueReference
N-linked 151 PubMed, HPRD
N-linked 282 PubMed, HPRD
Localisation

Protein: TLR2

LocalisationReference
Plasma membrane HPRD

Protein: CD14

LocalisationReference
ER HPRD
Golgi HPRD
Plasma membrane HPRD
Lysosome HPRD
Endosome HPRD
Secreted HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between TLR2 and CD14 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TLR2 andCD14. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TLR2 has 902 interactors and CD14 has 756 interactors of which there are 620 common interactors.

Common InteractorName of Common InteractorScore for TLR2-Interactor (?)Score for CD14-Interactor (?)
TLR4 TLR4: Toll-like receptor 4 precursor 6.03 0.515
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 5.45 0.308
CSPG2 N/A 3.59 0.917
CFP CFP, PFC: Properdin precursor 1.62 2.75
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 1.48 0.032
TLR5 N/A 1.36 0.137
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 1.32 0.440
MYD88 1.22 0.137
IL1RN IL1RN, IL1F3, IL1RA: Interleukin-1 receptor antagonist protein precursor 1.13 0.032
FPR1 FPR1: fMet-Leu-Phe receptor 0.923 0.144
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.917 0.917
LILRB2 N/A 0.881 0.049
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.852 0.144
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.852 0.070
TLR1 TLR1, KIAA0012: Toll-like receptor 1 precursor 0.739 0.050
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.692 0.0416
CARD15 NOD2, CARD15, IBD1: Nucleotide-binding oligomerization domain-containing protein 0.692 0.231
FCN1 FCN1, FCNM: Ficolin-1 precursor 0.620 0.881
LILRB1 N/A 0.613 0.025
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.566 0.025
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.515 0.269
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.515 0.515
TLR7 TLR7, UNQ248/PRO285: Toll-like receptor 7 precursor 0.491 0.041
HCK N/A 0.472 0.157
TLR6 TLR6: Toll-like receptor 6 precursor 0.440 0.050
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.430 0.260
FGL2 FGL2: Fibroleukin precursor 0.423 0.923
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.416 0.260
MNDA MNDA: Myeloid cell nuclear differentiation antigen 0.392 0.061
LY96 LY96, ESOP1, MD2: Lymphocyte antigen 96 precursor 0.354 0.173
IL8 IL8: Interleukin-8 precursor 0.340 0.052
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.308 0.144
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.308 0.087
FCGR2A FCGR2A: Fc of IgG, low affinity IIa, receptor 0.308 0.087
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.308 0.308
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.307 0.0425
SIGIRR SIGIRR, UNQ301/PRO342: Single Ig IL-1-related receptor 0.305 0.0308
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.304 0.307
TREM1 TREM1: Triggering receptor expressed on myeloid cells 1 precursor 0.294 0.042
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.276 0.144
PPBP PPBP, CTAP3, SCYB7, TGB1, THBGB1: Platelet basic protein precursor 0.274 0.0425
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.274 0.202
CD302 CD302, CLEC13A, DCL1, KIAA0022: CD302 antigen precursor 0.270 0.090
TLR9 TLR9, UNQ5798/PRO19605: Toll-like receptor 9 precursor 0.265 0.027
TLR8 TLR8, UNQ249/PRO286: Toll-like receptor 8 precursor 0.265 0.027
TICAM1 TRIF, TICAM-1: Toll-like receptor adapter molecule 1 0.265 0.027
IL17RD N/A 0.265 0.027
IL1RAP N/A 0.265 0.027
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.260 0.052
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.253 0.125
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.246 0.091
LCP1 LCP1, PLS2: Plastin-2 0.246 0.091
FLII FLII, FLIL: Protein flightless-1 homolog 0.246 0.274
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.241 0.163
TLR10 N/A 0.237 0.027
BIRC1 BIRC1, NAIP: Baculoviral IAP repeat-containing protein 1 0.231 0.108
FBXL5 FBXL5, FBL4, FBL5, FLR1: F-box/LRR-repeat protein 5 0.231 0.108
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.210 0.070
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.210 0.052
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.210 0.052
SORL1 SORL1: Sortilin-related receptor precursor 0.210 0.080
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.210 0.052
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.210 0.070
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.210 0.080
PF4 PF4, CXCL4, SCYB4: Platelet factor 4 precursor 0.202 0.032
FLNA FLNA, FLN, FLN1: Filamin-A 0.202 0.202
FADD FADD, MORT1: Protein FADD 0.191 0.191
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.185 0.125
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.181 0.166
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.166 0.166
CIITA CIITA, MHC2TA: MHC class II transactivator 0.166 0.126
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.166 0.126
EDA N/A 0.165 0.165
KIR3DL1 N/A 0.165 0.028
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.165 0.165
OPTC OPTC, OPT: Opticin precursor 0.165 0.165
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.083
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.083
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.165 0.165
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.028
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.052
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.165 0.165
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.163 0.163
BST1 BST1: ADP-ribosyl cyclase 2 precursor 0.160 0.053
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.157 0.157
PSAP PSAP, GLBA, SAP1: Proactivator polypeptide precursor [Contains: Saposin-A 0.157 0.308
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.157 0.074
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.157 0.074
GMIP GMIP: GEM-interacting protein 0.157 0.0446
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.157 0.0446
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.155 0.0425
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.153 0.124
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.152 0.026
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.152 0.123
RPS10 RPS10: 40S ribosomal protein S10 0.148 0.126
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.148 0.028
JAG2 JAG2: Jagged-2 precursor 0.148 0.165
BSG N/A 0.148 0.028
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.083
IRAK3 IRAK3: Interleukin-1 receptor-associated kinase 3 0.137 0.137
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.132 0.132
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.129 0.144
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.127 0.0425
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.127 0.032
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.127 0.096
CTSS CTSS: Cathepsin S precursor 0.126 0.042
CCL4 CCL4, CCL4L, LAG1, MIP1B, SCYA4, SCYA4L: Small-inducible cytokine A4 precursor 0.126 0.026
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.126 0.100
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.125 0.101
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.123 0.055
F10 F10: Coagulation factor X precursor 0.123 1.76
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.118 0.052
PPT1 PPT1, PPT: Palmitoyl-protein thioesterase 1 precursor 0.113 0.042
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.113 0.152
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.112 0.101
KIAA0690 N/A 0.112 0.101
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.111 0.061
VAV1 VAV1, VAV: Proto-oncogene vav 0.111 0.091
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.110 0.031
CASP9 CASP9, MCH6: Caspase-9 precursor 0.109 0.109
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.109 0.165
C1QC C1QC, C1QG: Complement C1q subcomponent subunit C precursor 0.109 0.165
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.109 0.109
CCL15 CCL15, MIP5, NCC3, SCYA15: Small-inducible cytokine A15 precursor 0.109 0.028
DCN DCN: Decorin precursor 0.109 0.165
CCL26 CCL26, SCYA26, UNQ216/PRO242: Small-inducible cytokine A26 precursor 0.109 0.028
LOC643930 CCL3L1, D17S1718, G0S19-2, SCYA3L1: Small-inducible cytokine A3-like 1 precursor 0.109 0.028
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.052
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.034
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.109 0.109
SDC1 SDC1, SDC: Syndecan-1 precursor 0.109 0.026
TPBG TPBG, 5T4: Trophoblast glycoprotein precursor 0.109 0.109
GP1BA N/A 0.109 0.123
PVR PVR, PVS: Poliovirus receptor precursor 0.098 0.055
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.098 0.098
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.098 0.031
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.098 0.109
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.049
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.083
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.098 0.049
COL18A1 N/A 0.098 0.165
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.098 0.165
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.098 0.109
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.097 0.026
TSHR N/A 0.097 0.109
DCC DCC: Netrin receptor DCC precursor 0.097 0.055
GP5 GP5: Platelet glycoprotein V precursor 0.097 0.109
CSPG4 CSPG4, MCSP: Chondroitin sulfate proteoglycan 4 precursor 0.097 0.055
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.097 0.055
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.096 0.077
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.096 0.026
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.096 0.032
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.096 0.174
SGSH SGSH, HSS: N-sulphoglucosamine sulphohydrolase precursor 0.094 0.085
CD93 CD93, C1QR1, MXRA4: Complement component C1q receptor precursor 0.090 0.090
LILRA3 LILRA3, ILT6, LIR4: Leukocyte immunoglobulin-like receptor subfamily A member 3 0.090 0.049
TNFSF10 TNFSF10: Uncharacterized protein TNFSF10 0.090 0.042
CD1D CD1D: T-cell surface glycoprotein CD1d precursor 0.090 0.049
THOC1 THOC1, HPR1: THO complex subunit 1 0.090 0.123
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.090 0.062
HSP90AA1 Hsp89-alpha-delta-N 0.090 0.037
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.090 0.037
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.088 0.031
CD44 N/A 0.087 0.087
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.087 0.087
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.083 0.083
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.083 0.028
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.083 0.028
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.083 0.052
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.083 0.052
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.083 0.028
FN1 N/A 0.083 0.083
TMPRSS9 N/A 0.083 0.052
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.083 0.052
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.083 0.083
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.083 0.052
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.083 0.028
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.083 0.028
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.083 0.028
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.083 0.052
CYBB CYBB, NOX2: Cytochrome b-245 heavy chain 0.082 0.027
TYROBP N/A 0.082 0.027
TNFAIP2 TNFAIP2: Tumor necrosis factor, alpha-induced protein 2 0.082 0.027
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.0818 0.061
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.0818 0.075
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.081 0.081
SFTPD SFTPD, PSPD, SFTP4: Pulmonary surfactant-associated protein D precursor 0.081 0.123
BACH1 BACH1: Transcription regulator protein BACH1 0.081 0.039
ITGAE ITGAE: Integrin alpha-E precursor 0.080 0.060
NCSTN NCSTN, KIAA0253, UNQ1874/PRO4317: Nicastrin precursor 0.078 0.070
F7 F7: Coagulation factor VII precursor 0.078 1.53
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.077 0.155
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.077 0.062
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.077 0.048
LGALS3 LGALS3, MAC2: Galectin-3 0.075 0.155
CNTN1 CNTN1: Contactin-1 precursor 0.075 0.052
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.075 0.052
CNTN4 CNTN4: Contactin-4 precursor 0.075 0.052
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.075 0.083
ATRN N/A 0.075 0.083
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.075 0.083
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.074 0.061
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.074 0.0446
IRS2 IRS2: Insulin receptor substrate 2 0.074 0.074
LYN LYN: Tyrosine-protein kinase Lyn 0.074 0.036
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.073 0.062
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.073 0.037
RLN2 RLN2: Prorelaxin H2 precursor [Contains: Relaxin B chain; Relaxin A chain] 0.0727 0.110
CGA CGA: Glycoprotein hormones alpha chain precursor 0.072 0.123
IGF2 IGF2, PP1446: Insulin-like growth factor II precursor 0.072 0.123
COL5A2 N/A 0.072 0.109
ASPN ASPN: ASPN protein 0.072 0.109
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.072 0.055
KERA KERA: Keratocan precursor 0.072 0.109
TSHB TSHB: Thyrotropin subunit beta precursor 0.072 0.109
COL1A1 COL1A1: Collagen alpha-1(I) chain precursor 0.072 0.109
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.072 0.072
COL17A1 COL17A1, BP180, BPAG2: Collagen alpha-1(XVII) chain 0.072 0.109
FSHB FSHB: Follitropin subunit beta precursor 0.072 0.123
COL3A1 COL3A1: Collagen alpha-1(III) chain precursor 0.072 0.109
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.072 0.032
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.072 0.123
LHB LHB: Lutropin subunit beta precursor 0.072 0.109
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.072 0.072
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.072 0.123
SERPINA4 SERPINA4, KST, PI4: Kallistatin precursor 0.072 0.096
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.072 0.055
BMX N/A 0.072 0.032
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.072 0.062
SFTPA2 SFTPA2, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A2 precursor 0.072 0.123
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.072 0.062
LUM LUM, LDC: Lumican precursor 0.072 0.109
C1QA C1QA: Complement C1q subcomponent subunit A precursor 0.072 0.123
THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 0.072 0.109
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.072 0.109
INS INS: Insulin precursor [Contains: Insulin B chain; Insulin A chain] 0.072 0.109
ADIPOQ ADIPOQ, ACDC, ACRP30, APM1, GBP28: Adiponectin precursor 0.072 0.109
FPRL1 FPRL1, FPR2, FPRH1, LXA4R: FMLP-related receptor I 0.070 0.0425
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.070 0.052
PTPNS1 N/A 0.070 0.052
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.070 0.070
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.070 0.070
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.069 0.060
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.067 0.067
LRRC8D LRRC8D, LRRC5, UNQ213/PRO239: Leucine-rich repeat-containing protein 8D 0.067 0.050
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.067 0.046
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.067 0.080
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.066 0.036
VNN2 VNN2: Vascular non-inflammatory molecule 2 precursor 0.066 0.087
STAT6 STAT6: Signal transducer and activator of transcription 6 0.066 0.036
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.066 0.036
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.066 0.0446
CASP4 CASP4, ICH2: Caspase-4 precursor 0.065 0.053
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.065 0.098
MUC2 MUC2, SMUC: Mucin-2 precursor 0.065 0.098
DSPG3 EPYC, DSPG3, PGLB: Epiphycan precursor 0.065 0.109
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.065 0.062
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.065 0.049
COL15A1 COL15A1: Collagen alpha-1(XV) chain precursor [Contains: Endostatin 0.065 0.109
BGN BGN: Biglycan precursor 0.065 0.109
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.065 0.049
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.065 0.098
NDP NDP: Norrin precursor 0.065 0.098
IGFALS IGFALS, ALS: Insulin-like growth factor-binding protein complex acid labile chai 0.064 0.191
COL4A1 N/A 0.064 0.109
CTGF CTGF, CCN2, HCS24: Connective tissue growth factor precursor 0.064 0.109
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.064 0.037
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.055
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.064 0.055
COL5A1 N/A 0.063 0.115
VIM VIM: Vimentin 0.063 0.063
EPOR EPOR: Erythropoietin receptor precursor 0.062 0.039
CD69 CD69: Early activation antigen CD69 0.062 0.055
THBD THBD, THRM: Thrombomodulin precursor 0.062 0.062
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.062 0.034
LY86 LY86, MD1: Lymphocyte antigen 86 precursor 0.061 0.037
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.060 0.026
NXF1 NXF1, TAP: Nuclear RNA export factor 1 0.059 0.053
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.058 0.098
VWF VWF, F8VWF: von Willebrand factor precursor 0.058 0.109
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.058 0.032
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.057 0.137
LGALS2 LGALS2: Galectin-2 0.057 0.042
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.057 0.063
OSM OSM: Oncostatin-M precursor 0.057 0.060
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.056 0.130
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.056 0.039
GNA13 GNA13: Guanine nucleotide-binding protein alpha-13 subunit 0.056 0.062
INSR INSR: Insulin receptor precursor 0.056 0.039
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.056 0.031
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.055 0.039
PRLR PRLR: Prolactin receptor precursor 0.055 0.034
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.055 0.034
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.055 0.055
IL9R IL9R: Interleukin-9 receptor precursor 0.055 0.034
ITGB4 N/A 0.055 0.055
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 0.055 0.055
GHR GHR: Growth hormone receptor precursor 0.055 0.039
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.055 0.031
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.055 0.031
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.055 0.096
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.055 0.055
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.054 0.046
JAK1 0.054 0.037
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.054 0.026
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.054 0.080
RIPK2 RIPK2, CARDIAK, UNQ277/PRO314/PRO34092, RICK, RIP2: Receptor-interacting serine/ 0.053 0.039
DLK1 DLK1, DLK: Delta-like protein precursor 0.052 0.028
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.052 0.0425
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.052 0.032
TNFRSF10C TNFRSF10C, DCR1, UNQ321/PRO366, LIT, TRAILR3, TRID: Tumor necrosis factor recept 0.052 0.026
IL8RB IL8RB, CXCR2: High affinity interleukin-8 receptor B 0.052 0.026
HLA-DRA 0.052 0.0425
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.052 0.052
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.052 1.14
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
COL11A1 COL11A1, COLL6: Collagen alpha-1(XI) chain precursor 0.051 0.051
GM2A GM2A: Ganglioside GM2 activator precursor 0.051 0.051
FMOD FMOD, FM: Fibromodulin precursor 0.051 0.051
CPN2 CPN2, ACBP: Carboxypeptidase N subunit 2 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.051
C1QB N/A 0.051 0.051
COL2A1 N/A 0.051 0.051
COL4A2 COL4A2: Collagen alpha-2(IV) chain precursor [Contains: Canstatin] 0.051 0.051
GP9 GP9: Platelet glycoprotein IX precursor 0.051 0.0416
SI SI: Sucrase-isomaltase, intestinal [Contains: Sucrase 0.051 0.025
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.051 0.063
F2 F2: Prothrombin precursor 0.051 0.241
PROC PROC: Vitamin K-dependent protein C precursor 0.051 1.76
XPO1 XPO1, CRM1: Exportin-1 0.051 0.037
NRAS NRAS, HRAS1: GTPase NRas precursor 0.051 0.037
LRCH4 LRCH4, LRN, LRRN1, LRRN4: Leucine-rich repeat and calponin homology domain-conta 0.050 0.041
SELE SELE, ELAM1: E-selectin precursor 0.049 0.055
MS4A6A N/A 0.049 0.049
CASP6 CASP6, MCH2: Caspase-6 precursor 0.049 0.049
F11 F11: Coagulation factor XI precursor 0.049 0.052
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.049 0.028
CASP14 CASP14: Caspase-14 precursor 0.049 0.049
IFNG IFNG: Interferon gamma precursor 0.049 0.052
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.049 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.049 0.049
MEP1A MEP1A: Meprin A subunit alpha precursor 0.049 0.034
HPN HPN, TMPRSS1: Serine protease hepsin 0.049 0.060
MEP1B MEP1B: Meprin A subunit beta precursor 0.049 0.034
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.049 0.034
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.049 0.039
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.049 0.055
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.049 0.034
ARRB2 N/A 0.0479 0.025
GABARAP GABARAP, FLC3B, HT004: Gamma-aminobutyric acid receptor-associated protein 0.0479 0.053
RNH1 RNH1, PRI, RNH: Ribonuclease inhibitor 0.047 0.053
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.047 0.052
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.046 0.052
F9 F9: Coagulation factor IX precursor 0.0462 1.41
HD HD, IT15: Huntingtin 0.046 0.037
LMAN2 LMAN2, C5orf8: Vesicular integral-membrane protein VIP36 precursor 0.046 0.063
GNAI2 Galphai2 protein 0.045 0.051
IL5 IL5: Interleukin-5 precursor 0.0453 0.048
GZMB Endogenous granzyme B 0.0453 0.039
RRAS RRAS: Ras-related protein R-Ras precursor 0.0453 0.046
AZU1 AZU1: Azurocidin precursor 0.0453 0.039
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.0446 0.036
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0446 0.0446
PLA2G7 PAFAH, PLA2G7: Platelet-activating factor acetylhydrolase precursor 0.0446 0.144
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0446 0.036
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.0446 0.0446
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.0446 0.027
ZYX ZYX: Zyxin 0.0446 0.036
VASP VASP: Vasodilator-stimulated phosphoprotein 0.0446 0.027
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.044 0.055
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.044 0.034
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.044 0.049
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.044 0.049
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.044 0.049
PTPRZ1 N/A 0.044 0.031
TNC TNC, HXB: Tenascin precursor 0.044 0.031
CASP8 CASP8, MCH5: Caspase-8 precursor 0.044 0.044
PLAT PLAT: Tissue-type plasminogen activator precursor 0.044 0.083
KLK3 KLK3, APS: Prostate-specific antigen precursor 0.044 0.052
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.044 0.083
RAB5B RAB5B: Ras-related protein Rab-5B 0.044 0.04
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.044 0.049
ITGB7 ITGB7: Integrin beta-7 precursor 0.043 0.039
CCR5 CCR5: CCR5 receptor (Fragment) 0.0425 0.032
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.0425 0.0425
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.042 0.042
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.041 0.037
FUBP1 N/A 0.0407 0.033
CD180 LY64, CD180, RP105: CD180 antigen precursor 0.041 0.041
DGCR2 DGCR2, IDD, KIAA0163: Integral membrane protein DGCR2/IDD precursor 0.041 0.041
DSP DSP: Desmoplakin 0.04 0.028
AXIN1 0.04 0.04
MSN MSN: Moesin 0.040 0.027
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.040 0.027
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.040 0.036
PSCD4 PSCD4, CYT4: Cytohesin-4 0.040 0.027
DOK1 DOK1: Docking protein 1 0.040 0.0446
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.040 0.027
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.040 0.044
NEO1 NEO1, NGN: Neogenin precursor 0.040 0.044
AREG AREG, SDGF: Amphiregulin precursor 0.039 0.034
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.039 0.034
EGF EGF: Pro-epidermal growth factor precursor 0.039 0.034
CARD8 CARD8, KIAA0955, NDPP1: Caspase recruitment domain-containing protein 8 0.039 0.032
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.038 0.032
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.038 0.042
CSF2 CSF2, GMCSF: Granulocyte-macrophage colony-stimulating factor precursor 0.037 0.048
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.037 0.062
PRTN3 PRTN3, MBN: Myeloblastin precursor 0.037 0.039
ELA2 ELA2: Leukocyte elastase precursor 0.037 0.039
HP HP: Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta c 0.037 0.080
CTSG CTSG: Cathepsin G precursor 0.037 0.039
IL2 IL2: Interleukin 2 0.037 0.039
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.037 0.039
TBCE TBCE: Tubulin-specific chaperone E 0.036 0.033
GAA GAA: Uncharacterized protein GAA 0.036 0.087
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.036 0.036
CST3 CST3: Cystatin-C precursor 0.036 0.087
MARK2 N/A 0.036 0.036
DAPP1 N/A 0.036 0.027
AHNAK AHNAK: AHNAK protein 0.036 0.036
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.036 0.027
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.036 0.036
BMP1 N/A 0.036 0.028
LDLR LDLR: Low-density lipoprotein receptor precursor 0.035 0.039
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.035 0.039
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.035 0.035
RABGGTA RABGGTA: Geranylgeranyl transferase type-2 subunit alpha 0.035 0.041
ANP32A ANP32A, C15orf1, LANP, MAPM, PHAP1: Acidic leucine-rich nuclear phosphoprotein 3 0.035 0.041
BIRC2 BIRC2, API1, IAP2, MIHB, RNF48: Baculoviral IAP repeat-containing protein 2 0.035 0.032
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.035 0.031
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.034 0.060
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.034 0.031
DNASE1 DNASE1, DNL1, DRNI: Deoxyribonuclease-1 precursor 0.034 0.034
BGLAP BGLAP: Osteocalcin precursor 0.0333 0.152
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.033 0.030
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.033 0.037
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.033 0.032
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.033 0.077
LPA LPA: Apolipoprotein(a) precursor 0.033 0.077
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.033 0.037
CNN3 CNN3: Calponin-3 0.033 0.029
PRPH PRPH, NEF4, PRPH1: Peripherin 0.033 0.029
TACSTD1 TACSTD1, GA733-2, M1S2, M4S1, MIC18, TROP1: Tumor-associated calcium signal tran 0.032 0.055
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.032 0.034
EPO EPO: Erythropoietin precursor 0.032 0.039
CLEC3B CLEC3B, TNA: Tetranectin precursor 0.032 0.062
LIF LIF, HILDA: Leukemia inhibitory factor precursor 0.032 0.034
DES DES: Desmin 0.032 0.032
REG3A REG3A, HIP, PAP, PAP1: Regenerating islet-derived protein 3 alpha precursor 0.032 0.055
CFB CFB, BF, BFD: Complement factor B precursor 0.032 0.060
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.037
CMA1 CMA1, CYH, CYM: Chymase precursor 0.032 0.039
IFNW1 IFNW1: Interferon omega-1 precursor 0.032 0.034
IL3 IL3: Interleukin-3 precursor 0.032 0.031
IFNA14 IFNA14: Interferon alpha-14 precursor 0.032 0.034
C8A C8A: Complement component C8 alpha chain precursor 0.032 0.096
REG1B REG1B, REGL: Lithostathine 1 beta precursor 0.032 0.055
PRL PRL: Prolactin precursor 0.032 0.034
APCS APCS, PTX2: Serum amyloid P-component precursor 0.032 0.096
IL6 IL6, IFNB2: Interleukin-6 precursor 0.032 0.034
TG TG: Thyroglobulin precursor 0.032 0.055
ELA3B ELA3B: Elastase-3B precursor 0.032 0.034
F12 F12: Coagulation factor XII precursor 0.032 0.096
REG1B REG1A, PSPS, REG: Lithostathine 1 alpha precursor 0.032 0.055
C2 C2: Complement C2 precursor 0.032 0.060
PRSS1 PRSS1, TRP1, TRY1, TRYP1: Trypsin-1 precursor 0.032 0.034
ATP2B1 N/A 0.032 0.026
CPD CPD: Carboxypeptidase D precursor 0.032 0.0425
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.032 0.036
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.032 0.036
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.032 0.027
SYK SYK: Tyrosine-protein kinase SYK 0.032 0.027
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.032 0.027
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.032 0.0446
GSK3B N/A 0.032 0.027
ACTG1 ACTB: Actin, cytoplasmic 1 0.032 0.036
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.0308 0.034
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.030 0.0263
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.030 0.033
PSMD12 PSMD12: 26S proteasome non-ATPase regulatory subunit 12 0.030 0.029
SPON1 SPON1, KIAA0762, VSGP: Spondin-1 precursor 0.029 0.049
PARVA PARVA, MXRA2: Alpha-parvin 0.029 0.029
INHA INHA: Inhibin alpha chain precursor 0.029 0.055
NEFH NEFH, KIAA0845, NFH: Neurofilament heavy polypeptide 0.029 0.032
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.029 0.049
CFI CFI, IF: Complement factor I precursor 0.029 0.034
C1R C1R: Complement C1r subcomponent precursor 0.029 0.048
SHBG SHBG: Sex hormone-binding globulin precursor 0.029 0.055
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.029 0.029
IFNB1 IFNB1, IFB, IFNB: Interferon beta precursor 0.029 0.031
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.029 0.029
C1S C1S: Complement C1s subcomponent precursor 0.029 0.039
GFAP GFAP: Glial fibrillary acidic protein 0.029 0.0263
PRSS22 PRSS22, BSSP4, SP001LA, PRSS26, UNQ302/PRO343: Brain-specific serine protease 4 0.029 0.034
LOC645745 MT1H: Metallothionein-1H 0.029 0.0416
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.029 0.033
MT2A MT2A, CES1, MT2: Metallothionein-2 0.029 0.051
MT1X MT1X: Metallothionein-1X 0.029 0.0416
MT1F MT1F, PRO0376: Metallothionein-1F 0.029 0.051
LAMA2 LAMA2: Uncharacterized protein LAMA2 0.029 0.055
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.032
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.029 0.055
KLK1 KLK1: Kallikrein-1 precursor 0.029 0.034
C6 C6: Complement component C6 precursor 0.029 0.077
C8B C8B: Complement component C8 beta chain precursor 0.029 0.077
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.029 0.032
PLG PLG: Plasminogen precursor 0.029 0.096
C7 C7: Complement component C7 precursor 0.029 0.055
ATP1B3 ATP1B3: Sodium/potassium-transporting ATPase subunit beta-3 0.029 0.026
ITGA2B ITGA2B, GP2B, ITGAB: Integrin alpha-IIb precursor 0.029 0.026
TRHR TRHR: Thyrotropin-releasing hormone receptor 0.029 0.032
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.029 0.026
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.029 0.026
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.029 0.0425
SNAP25 N/A 0.028 0.028
PTPRA N/A 0.028 0.028
PILRA PILRA: Paired immunoglobulin-like type 2 receptor alpha precursor 0.028 0.028
LAIR1 LAIR1, CD305: Leukocyte-associated immunoglobulin-like receptor 1 precursor 0.028 0.028
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.028
ITGB1 N/A 0.028 0.028
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.028 0.028
CDH6 CDH6: Cadherin-6 precursor 0.028 0.028
DRD2 DRD2: D(2) dopamine receptor 0.028 0.028
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.028 0.028
GPRC5A GPRC5A, GPCR5A, RAI3, RAIG1: Retinoic acid-induced protein 3 0.028 0.028
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.028 0.028
TBXA2R TBXA2R: Thromboxane A2 receptor 0.028 0.028
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.028
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.028 0.028
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.028 0.028
CSF3R N/A 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
PCDH7 N/A 0.028 0.028
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.028 0.028
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.028 0.028
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.028 0.028
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.028
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.028 0.028
TREML1 TREML1, TLT1, UNQ1825/PRO3438: Trem-like transcript 1 protein precursor 0.028 0.028
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.028 0.028
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.028
GPC2 GPC2: Glypican-2 precursor 0.028 0.028
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.028
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.028
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.028
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.028 0.028
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.028 0.028
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.028
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.028
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.028 0.028
CANX CANX: Calnexin precursor 0.028 0.031
PDIA6 PDIA6, TXNDC7: Protein disulfide-isomerase A6 precursor 0.028 0.025
P4HB P4HB, ERBA2L, PDI, PDIA1, PO4DB: Protein disulfide-isomerase precursor 0.028 0.039
ECGF1 ECGF1: Thymidine phosphorylase precursor 0.027 0.082
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.027 0.027
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.027 0.027
SYMPK SYMPK, SPK: Symplekin 0.027 0.037
NPC2 NPC2: Epididymal secretory protein E1 precursor 0.027 0.030
LRRC21 LRRC21, PAL: Leucine-rich repeat-containing protein 21 precursor 0.027 0.027
SCARA3 SCARA3, CSR: Scavenger receptor class A member 3 0.027 0.027
LRRTM3 N/A 0.027 0.027
C1QTNF6 C1QTNF6, C22:RP1-151B14.4-004, hCG_2039683: OTTHUMP00000028739 0.027 0.027
SLITRK2 SLITRK2, CXorf2, UNQ9197/PRO34756, KIAA1854, SLITL1: SLIT and NTRK-like protein 0.027 0.027
AMIGO3 AMIGO3, ALI3, UNQ6084/PRO20089, KIAA1851: Amphoterin-induced protein 3 precursor 0.027 0.027
LRRC8C LRRC8C, AD158: Leucine-rich repeat-containing protein 8C 0.027 0.027
TNFRSF10A TNFRSF10A, APO2, DR4, TRAILR1: Tumor necrosis factor receptor superfamily member 0.027 0.027
SLITRK1 SLITRK1, KIAA1910, UNQ233/PRO266, LRRC12: SLIT and NTRK-like protein 1 precursor 0.027 0.027
LGI4 LGI4, LGIL3, UNQ6515/PRO21485: Leucine-rich repeat LGI family member 4 precursor 0.027 0.027
LRRC33 LRRC33, UNQ3030/PRO9833: Leucine-rich repeat-containing protein 33 precursor 0.027 0.027
LGI3 LGI3, LGIL4, UNQ8190/PRO23199: Leucine-rich repeat LGI family member 3 precursor 0.027 0.027
C20orf75 C20orf75: Uncharacterized protein C20orf75 precursor 0.027 0.027
TNFRSF10B TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9: Tumor necrosis factor receptor 0.027 0.027
FLJ44691 LRIT3: LRIT3 protein 0.027 0.027
LRRC8A LRRC8A, KIAA1437, UNQ221/PRO247, LRRC8: Leucine-rich repeat-containing protein 8 0.027 0.027
SLITRK4 SLITRK4: SLIT and NTRK-like protein 4 precursor 0.027 0.027
COL11A2 COL11A2: Collagen alpha-2(XI) chain precursor 0.027 0.027
TNFRSF25 TNFRSF25, APO3, UNQ455/PRO779, DDR3, DR3, TNFRSF12, WSL, WSL1: Tumor necrosis fa 0.027 0.027
NELL2 NELL2, NRP2: Protein kinase C-binding protein NELL2 precursor 0.027 0.027
SLITRK6 SLITRK6: SLIT and NTRK-like protein 6 precursor 0.027 0.027
LRRTM1 LRRTM1, UNQ675/PRO1309: Leucine-rich repeat transmembrane neuronal protein 1 pre 0.027 0.027
LGR4 LGR4, GPR48: Leucine-rich repeat-containing G-protein coupled receptor 4 precurs 0.027 0.027
RTN4RL2 RTN4RL2, NGRH1, NGRL3: Reticulon-4 receptor-like 2 precursor 0.027 0.027
LRFN5 LRFN5, C14orf146: Leucine-rich repeat and fibronectin type-III domain-containing 0.027 0.027
LGALS9 N/A 0.027 0.042
RNASE2 RNASE2, EDN, RNS2: Non-secretory ribonuclease precursor 0.027 0.0425
F5 F5: Coagulation factor V precursor 0.027 0.087
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.027 0.027
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.0263 0.030
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0263 0.0263
ITIH4 ITIH4, IHRP, PRO1851, ITIHL1, PK120: Inter-alpha-trypsin inhibitor heavy chain H 0.0263 0.060
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.0263 0.0263
COL16A1 COL16A1: Collagen alpha-1(XVI) chain precursor 0.026 0.033
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.026 0.029
KLK6 KLK6, PRSS18, PRSS9: Kallikrein-6 precursor 0.026 0.031
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.026 0.049
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.026 0.031
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.028
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.025 0.028
GPC3 GPC3, OCI5: Glypican-3 precursor 0.025 0.028
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.025 0.028
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.025 0.028
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.025 0.028
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.025 0.028
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.028
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.025 0.028
C2orf7 PAP21, C2orf7, UNQ833/PRO1760: Protease-associated domain-containing protein of 0.025 0.028
ATP1B1 N/A 0.025 0.028
FGFR2 N/A 0.025 0.028
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.025 0.028
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.028
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.025 0.028
SLC7A3 SLC7A3, ATRC3, CAT3: Cationic amino acid transporter 3 0.025 0.028
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.025 0.028
AQP4 AQP4: Aquaporin-4 0.025 0.028
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.025 0.028
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.025 0.028
TPP1 TPP1, CLN2, GIG1, UNQ267/PRO304: Tripeptidyl-peptidase 1 precursor 0.025 0.025
TNRC5 CNPY3, CTG4A, HSPC084, ERDA5, UNQ1934/PRO4409, TNRC5: Protein canopy homolog 3 p 0.025 0.025
2.15E-3
Total Score 1.57