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Evidence of Interaction Between RAF1 and STAM2

The interaction score between RAF1 and STAM2 is 10.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between RAF1 and STAM2 = 0.23

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.88E-3
Orthology
OrganismRAF1 OrthologueSTAM2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00303797 0.234 IPI00020178 0.47
worm Q07292 0.234 O01498 0.384
fly P11346 0.113 Q9XTL2 0.26

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.22E-3
Domains Domains present in RAF1 and STAM2:
Domains in RAF1Domains in STAM2
IPR000719 Protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding
IPR003116 Raf-like Ras-binding
IPR001452 SH3
IPR000108 Neutrophil cytosol factor 2
IPR002014 VHS
IPR003903 Ubiquitin interacting motif
IPR003110 Phosphorylated immunoreceptor signaling ITAM

The Chi square scores for co-occurrence of domains that are present in RAF1 and STAM2 are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR008271 Serine/threonine protein kinase, active site IPR001452 SH3 27.0049
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR008271 Serine/threonine protein kinase, active site IPR000108 Neutrophil cytosol factor 2 11.7731
IPR000719 Protein kinase IPR000108 Neutrophil cytosol factor 2 4.72045
IPR011009 Protein kinase-like IPR000108 Neutrophil cytosol factor 2 2.89179
IPR000719 Protein kinase IPR003110 Phosphorylated immunoreceptor signaling ITAM 2.82937
IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding IPR001452 SH3 0.299424
IPR003116 Raf-like Ras-binding IPR001452 SH3 0.129752
IPR011009 Protein kinase-like IPR002014 VHS 0.0560293
IPR000719 Protein kinase IPR003903 Ubiquitin interacting motif 0.0294147
IPR000719 Protein kinase IPR002014 VHS 0.0125758
IPR011009 Protein kinase-like IPR003110 Phosphorylated immunoreceptor signaling ITAM 0.011293
IPR011009 Protein kinase-like IPR003903 Ubiquitin interacting motif 0.0108342

The background colour of the table refers to:

  • Blue Domain is only present in RAF1
  • Yellow Domain is only present in STAM2
  • Green Domain is present in both RAF1 and STAM2

 0.083
Post-translational Modifications

Protein: RAF1

PTMResidueReference
Dephosphorylation 340 PubMed, HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 43 PubMed, HPRD
Phosphorylation 233 PubMed, HPRD
Phosphorylation 259 PubMed, HPRD
Phosphorylation 268 PubMed, HPRD
Phosphorylation 269 PubMed, HPRD
Phosphorylation 289 PubMed, HPRD
Phosphorylation 296 PubMed, HPRD
Phosphorylation 301 PubMed, HPRD
Phosphorylation 338 PubMed, HPRD
Phosphorylation 339 PubMed, HPRD
Phosphorylation 340 PubMed, HPRD
Phosphorylation 341 PubMed, HPRD
Phosphorylation 491 PubMed, HPRD
Phosphorylation 494 PubMed, HPRD
Phosphorylation 499 PubMed, HPRD
Phosphorylation 621 PubMed, HPRD
Phosphorylation 642 PubMed, HPRD
Phosphoserine 43 HPRD
Phosphoserine 259 PubMed, HPRD
Phosphoserine 338 PubMed, HPRD
Phosphoserine 499 PubMed, HPRD
Phosphoserine 621 HPRD
Phosphothreonine 268 PubMed, HPRD

Protein: STAM2

PTMResidueReference
Phosphorylation 192 PubMed, HPRD
Phosphorylation 371 PubMed, HPRD
Phosphorylation 372 PubMed, HPRD
Phosphorylation 374 PubMed, HPRD
Phosphotyrosine 371 HPRD
Phosphotyrosine 374 HPRD
Localisation

Protein: RAF1

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD

Protein: STAM2

LocalisationReference
Endosome HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between RAF1 and STAM2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between RAF1 andSTAM2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , RAF1 has 1538 interactors and STAM2 has 1227 interactors of which there are 853 common interactors.

Common InteractorName of Common InteractorScore for RAF1-Interactor (?)Score for STAM2-Interactor (?)
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 501.00 0.069
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 367.00 0.069
NRAS NRAS, HRAS1: GTPase NRas precursor 132.00 0.069
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 82.20 0.049
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 23.50 0.056
PRKACG PRKACG: cAMP-dependent protein kinase, gamma-catalytic subunit 6.81 0.028
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.852 0.077
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.852 0.191
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.852 0.123
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.763 0.171
MSN MSN: Moesin 0.763 0.136
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.763 0.139
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.763 0.171
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.763 0.069
STAT6 STAT6: Signal transducer and activator of transcription 6 0.763 0.171
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.763 0.136
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.763 0.136
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.763 0.086
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.763 0.086
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.515 0.191
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.515 0.191
VASP VASP: Vasodilator-stimulated phosphoprotein 0.515 0.152
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.503 0.073
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.461 0.110
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.461 0.171
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.461 0.069
SYK SYK: Tyrosine-protein kinase SYK 0.461 0.136
STK10 STK10: Uncharacterized protein STK10 0.461 0.069
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.461 82.20
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.136
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.461 0.086
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.461 0.171
LYN LYN: Tyrosine-protein kinase Lyn 0.461 0.171
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.461 0.029
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.461 0.069
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.461 0.110
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.461 0.136
PSCD4 PSCD4, CYT4: Cytohesin-4 0.461 0.136
CSK CSK: Tyrosine-protein kinase CSK 0.461 0.136
HCK N/A 0.461 0.171
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.426 0.172
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.416 0.096
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.416 0.096
ROCK1 ROCK1: Rho-associated protein kinase 1 0.416 0.307
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.385 0.171
WASPIP N/A 0.385 0.136
GMIP GMIP: GEM-interacting protein 0.385 0.086
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.385 0.136
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.372 0.029
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.372 0.086
RPS6KB1 N/A 0.372 0.171
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.372 0.171
NCK2 NCK2: Cytoplasmic protein NCK2 0.372 0.110
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.372 0.056
CRKL CRKL: Crk-like protein 0.372 0.110
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.372 0.171
DOK1 DOK1: Docking protein 1 0.372 0.171
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.372 0.086
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.372 0.029
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.086
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.372 0.110
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.372 0.110
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.372 0.136
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.372 0.171
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.372 0.029
JAK1 0.372 0.110
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.372 0.086
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.372 0.056
EEF2 EEF2, EF2: Elongation factor 2 0.372 0.069
PLEK PLEK, P47: Pleckstrin 0.340 0.100
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.340 0.081
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.307 0.152
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.307 0.109
YWHAQ YWHAQ: 14-3-3 protein theta 0.307 0.026
GAB2 N/A 0.307 0.109
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.304 0.041
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.275 0.056
VIL2 N/A 0.275 0.110
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.275 0.136
CDK2 CDK2: Cell division protein kinase 2 0.275 0.069
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.275 0.069
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.275 0.056
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.275 0.086
CDK4 CDK4: Cell division protein kinase 4 0.275 0.069
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.275 0.069
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.275 0.110
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.275 0.110
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.275 0.114
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.275 0.086
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.275 0.097
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.260 0.0416
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.260 0.152
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.260 0.032
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.260 0.152
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.260 0.026
LIMS1 N/A 0.260 0.032
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.152
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.251 0.077
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.251 0.152
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.098
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.251 0.096
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.251 0.123
STK16 N/A 0.251 0.191
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.152
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.251 0.191
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.251 0.062
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.246 0.041
SEC24B SEC24B: Protein transport protein Sec24B 0.233 0.043
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.233 0.136
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.233 0.056
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.233 0.069
FNBP1 N/A 0.233 0.136
KIAA1012 KIAA1012: Protein TRS85 homolog 0.233 0.114
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.086
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.233 0.136
CXorf9 N/A 0.233 0.136
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.233 0.069
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.233 0.069
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.233 0.069
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.227 0.051
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.227 0.113
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.225 0.056
CDK7 CDK7, MO15: Cell division protein kinase 7 0.225 0.114
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.225 0.110
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.088
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.225 0.086
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.225 0.097
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.225 0.097
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.225 0.171
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.225 0.097
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.210 0.152
ZYX ZYX: Zyxin 0.210 0.026
RAB8A RAB8A: RAB8A protein 0.204 0.058
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.191 0.109
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.191 0.191
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.191 0.307
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.191 0.123
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.188 0.086
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.188 0.139
COPE COPE: Coatomer subunit epsilon 0.188 0.086
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.188 0.114
CDC23 CDC23: Cell division cycle protein 23 homolog 0.188 0.086
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.188 0.069
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.188 0.069
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.188 0.069
CD2AP CD2AP: CD2-associated protein 0.188 0.136
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.188 0.038
TLN1 TLN1: Uncharacterized protein TLN1 0.188 0.136
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.188 0.136
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.188 0.114
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.188 0.086
SOS1 SOS1: Son of sevenless homolog 1 0.181 0.090
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.181 0.051
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.181 0.073
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.069
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.171 0.044
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.171 0.275
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.171 0.086
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.171 0.049
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.225
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.171 0.097
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.171 0.056
CDK6 CDK6: Cell division protein kinase 6 0.171 0.086
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.171 0.044
STAT2 STAT2: Signal transducer and activator of transcription 2 0.166 0.081
MAPK15 N/A 0.165 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.083
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.165 0.075
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.083
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.165
PSCD2 N/A 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.165 0.083
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.165
YWHAG YWHAG: 14-3-3 protein gamma 0.165 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.165 0.083
MAP2K5 N/A 0.165 0.083
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.165
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.155 0.046
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.155 0.0425
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.155 0.191
LIMK2 LIMK2: LIM domain kinase 2 0.155 0.077
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.155 0.077
H1FX H1FX: Histone H1x 0.153 0.030
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.153 0.100
CD44 N/A 0.153 0.046
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.153 0.057
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.152 0.152
PRKAA1 N/A 0.152 0.210
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.152 0.062
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.123
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.152 0.098
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.191
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.148 0.075
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.148 0.075
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.148 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.148
RAB5B RAB5B: Ras-related protein Rab-5B 0.148 0.075
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.148 0.075
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.148 0.148
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.075
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.075
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.075
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.148 0.148
ELMO1 N/A 0.148 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.148 0.075
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.075
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.148 0.075
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.148
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.075
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.075
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.148 0.075
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.025
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.148 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.148
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.148 0.075
ARHGEF7 N/A 0.148 0.148
STAT3 0.148 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.148 0.075
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.148 0.075
ATM ATM: Serine-protein kinase ATM 0.139 0.056
THOC1 THOC1, HPR1: THO complex subunit 1 0.139 0.029
HSP90AA1 Hsp89-alpha-delta-N 0.139 0.029
CTPS CTPS: CTP synthase 1 0.139 0.029
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.139 0.136
AIP AIP, XAP2: AH receptor-interacting protein 0.139 0.056
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.139 0.069
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.139 0.114
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.139 0.110
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.110
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.137 0.041
RIN1 RIN1: Ras and Rab interactor 1 0.136 0.110
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.136 0.275
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.136 0.097
PLD2 PLD2: Phospholipase D2 0.136 0.110
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.136 0.086
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.136 0.110
RASA3 RASA3: Ras GTPase-activating protein 3 0.136 0.110
APS SH2B2, APS: SH2B adapter protein 2 0.136 0.110
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.136 0.114
RRAS RRAS: Ras-related protein R-Ras precursor 0.136 0.049
CDK5 CDK5: Cell division protein kinase 5 0.136 0.044
DIAPH1 Diaphanous 1 0.129 0.029
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.129 0.086
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.129 0.069
QARS QARS: Glutaminyl-tRNA synthetase 0.129 0.029
ACTG1 ACTB: Actin, cytoplasmic 1 0.129 0.069
HNRPK N/A 0.129 0.029
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.129 0.069
LCP1 LCP1, PLS2: Plastin-2 0.129 0.054
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.129 0.029
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.086
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.077
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.127 0.096
CIITA CIITA, MHC2TA: MHC class II transactivator 0.127 0.026
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.126 0.100
RAB11A RAB11A, RAB11: Ras-related protein Rab-11A 0.126 0.076
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.0453
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.152
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.123 0.307
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.123 0.077
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.123 0.049
GRLF1 N/A 0.123 0.155
RIN3 N/A 0.123 0.028
NUP50 NUP50, NPAP60L, PRO1146: Nucleoporin 50 kDa 0.123 0.036
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.114 0.069
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.114 0.069
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.114 0.069
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.114 0.069
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.114 0.069
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.114 0.049
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.110
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.114 0.069
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.113 0.033
DAB2 DAB2, DOC2: Disabled homolog 2 0.110 0.097
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.110 0.056
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.110 0.275
RDX RDX: Radixin 0.110 0.136
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.110 0.049
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.110 0.056
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.110 0.086
PLD1 PLD1: Phospholipase D1 0.110 0.136
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.110 0.110
TST TST: Thiosulfate sulfurtransferase 0.110 0.056
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.110 0.049
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.110 0.136
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.110 0.035
SNCB SNCB: Beta-synuclein 0.110 0.035
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.109 0.044
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.049
RAB4A N/A 0.109 0.083
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.109 0.098
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.109 0.109
IRS1 IRS1: Insulin receptor substrate 1 0.109 0.152
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.109 0.077
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.109 0.062
BMX N/A 0.109 0.123
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.109 0.123
CDKL5 N/A 0.109 0.062
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.099 0.069
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.099 0.110
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.099 0.097
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.099 0.088
MYO3A MYO3A: Myosin IIIA 0.099 0.049
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.099 0.056
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.099 0.088
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.098 0.152
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.098 0.152
MCF2 MCF2, DBL: Proto-oncogene DBL 0.098 0.152
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.098 0.098
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.098 0.044
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.098 0.098
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.098 0.044
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.098 0.044
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.098 0.044
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.098
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.097 0.056
RRAD RRAD, RAD: GTP-binding protein RAD 0.097 0.056
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.097 0.049
DYRK3 N/A 0.097 0.233
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.097 0.088
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.097 0.110
PSD TYL: TYL protein 0.097 0.088
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.097 0.136
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.097 0.110
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.097 0.049
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.097 0.110
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.096 0.026
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.096 0.048
STAT4 STAT4: Signal transducer and activator of transcription 4 0.090 0.073
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.088 0.110
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.088 0.044
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.088 0.097
DAB1 DAB1: Disabled homolog 1 0.088 0.088
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.088 0.088
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.088 0.088
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.088 0.088
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.088
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.088 0.088
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.087 0.032
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.032
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.087 0.048
FUBP1 N/A 0.087 0.077
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.087 0.0333
WEE1 WEE1: Wee1-like protein kinase 0.086 0.114
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.086 0.069
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.086 0.049
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.086 0.086
FKBP4 FKBP4: FK506-binding protein 4 0.086 0.056
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.086 0.029
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.086 0.097
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.086 0.049
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.086 0.053
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.086 0.042
AXIN1 0.083 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.083 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.083 0.083
MAPKAPK5 N/A 0.083 0.083
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.083
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.083
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.028
CNN2 CNN2: Calponin-2 0.083 0.075
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.083
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.083
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.083 0.028
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.165
RANBP3 N/A 0.083 0.0308
PLEKHO1 PLEKHO1, CKIP1, OC120, HQ0024c: Pleckstrin homology domain-containing family O m 0.083 0.041
SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 0.083 0.0308
NCF2 NCF2: Neutrophil cytosol factor 2 0.083 0.0308
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.0818 0.051
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.0818 0.090
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.080 0.026
CENTA1 CENTA1: Centaurin-alpha 1 0.0794 0.041
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.078 0.088
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.078 0.029
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.078 0.086
FRG1 FRG1: Protein FRG1 0.078 0.029
RP2 RP2: Protein XRP2 0.078 0.029
GSK3B N/A 0.078 0.046
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.078 0.029
FLII FLII, FLIL: Protein flightless-1 homolog 0.078 0.054
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.078 0.029
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.078 0.043
XPO1 XPO1, CRM1: Exportin-1 0.078 0.029
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.029
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.152
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.251
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.077 0.191
DAPK2 DAPK2: Death-associated protein kinase 2 0.077 0.055
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.077
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.077 0.191
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.075 0.0453
MYB MYB: Myb proto-oncogene protein 0.075 0.0263
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.148
GIT2 N/A 0.075 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.075
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.148
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.075 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.075
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.075 0.025
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.148
MYO18A 0.075 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.075
LMO6 LMO6: LIM domain only protein 6 0.075 0.025
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.148
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.148
SNX3 N/A 0.075 0.075
TSC2 TSC2, TSC4: Tuberin 0.075 0.025
USP8 USP8, KIAA0055, UBPY: Ubiquitin carboxyl-terminal hydrolase 8 0.074 0.036
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.074 0.100
ELF1 ELF1: ETS-related transcription factor Elf-1 0.074 0.037
CRLF3 N/A 0.074 0.100
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.074 0.100
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.074 0.100
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.074 0.100
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.073 0.148
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.073 0.058
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.0727 0.044
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.072 0.029
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.072 0.081
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.072 0.065
SRPR SRPR: Uncharacterized protein SRPR 0.070 0.026
MVP MVP, LRP: Major vault protein 0.070 0.048
IFI35 N/A 0.070 0.026
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.070 0.0425
HD HD, IT15: Huntingtin 0.070 0.096
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.070 0.048
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.077
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.070 0.032
ABCF1 N/A 0.070 0.032
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.070 0.026
MPG N/A 0.070 0.026
DAPP1 N/A 0.070 0.026
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.070 0.042
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.067 0.027
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.067 0.041
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.067 0.029
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.067 0.033
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.067 0.033
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.067 0.073
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.067 0.041
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.067 0.033
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.066 0.113
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.066 0.113
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.066 0.113
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.065 0.029
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.065 0.081
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.064 0.073
PTPRZ1 N/A 0.064 0.058
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.090
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.064 0.065
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.064 0.064
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.064 0.033
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.064 0.064
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.063 0.110
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.063 0.038
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.029
VCP VCP: Transitional endoplasmic reticulum ATPase 0.063 0.029
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.063 0.188
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.063 0.069
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.063 0.043
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.063 0.046
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.063 0.029
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.029
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.063 0.029
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.063 0.046
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.136
SAPS3 N/A 0.063 0.029
MTMR3 MTMR3, KIAA0371, ZFYVE10: Myotubularin-related protein 3 0.060 0.036
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.073
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.058 0.033
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.058
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.058 0.026
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.058 0.029
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.057 0.065
EPOR EPOR: Erythropoietin receptor precursor 0.057 0.100
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.057 0.065
ERF ERF: ETS domain-containing transcription factor ERF 0.057 0.030
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.057 0.0453
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.057 0.100
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.057 0.065
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.056 0.056
SORBS3 SORBS3, SCAM1: Vinexin 0.056 0.171
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.056 0.136
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.056 0.136
LPP LPP: Lipoma-preferred partner 0.056 0.026
CTTN CTTN, EMS1: Src substrate cortactin 0.056 0.097
COBL N/A 0.056 0.088
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.0554 0.027
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.054 0.054
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.041
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.054 0.029
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.054 0.029
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.053 0.030
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.052 0.048
CHUK N/A 0.052 0.032
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.052 0.039
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.052 0.032
PHB2 PHB2, BAP, REA: Prohibitin-2 0.052 0.077
UBAP2 N/A 0.052 0.032
API5 N/A 0.052 0.026
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.052 0.0425
SAT SAT1, SAT: Diamine acetyltransferase 1 0.052 0.026
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
RAPH1 N/A 0.051 0.051
GRB10 N/A 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
MARK2 N/A 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
C9orf88 N/A 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.051 0.073
KIT KIT: Mast/stem cell growth factor receptor precursor 0.051 0.064
TLN2 TLN2: Uncharacterized protein TLN2 0.050 0.088
RAB11FIP5 RAB11FIP5, GAF1, KIAA0857, RIP11: Rab11 family-interacting protein 5 0.050 0.038
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.056
CSNK1G3 CSNK1G3: Casein kinase I isoform gamma-3 0.050 0.0308
SPTAN1 N/A 0.049 0.110
CNN3 CNN3: Calponin-3 0.049 0.049
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.049 0.109
SYTL4 Endocrine transmitter regulatory protein 0.049 0.109
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.049
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.049 0.109
SPAG1 SPAG1: Sperm-associated antigen 1 0.049 0.114
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.049 0.044
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.049 0.099
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.032
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.025
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.046 0.029
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.046 0.029
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.046 0.029
BRPF1 BRPF1, BR140: Peregrin 0.046 0.171
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.046 0.029
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.046 0.029
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.046 0.043
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.046 0.100
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
GRIN2C GRIN2C, NMDAR2C: Glutamate [NMDA] receptor subunit epsilon-3 precursor 0.046 0.026
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.0453 0.081
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.0453 0.072
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.0453 0.081
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.0453 0.081
GHR GHR: Growth hormone receptor precursor 0.0453 0.100
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.0446 0.166
SORL1 SORL1: Sortilin-related receptor precursor 0.0446 0.073
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.0446 0.100
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.0446 0.032
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.044 0.028
ADRBK2 ADRBK2, BARK2, GRK3: Beta-adrenergic receptor kinase 2 0.044 0.044
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.110
KLC2 KLC2: Kinesin light chain 2 0.044 0.050
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.044 0.097
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.044 0.049
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.110
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.044 0.136
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.044 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.044 0.098
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.044 0.036
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.044
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.044 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.044 0.098
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.098
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.044 0.036
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.098
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.0425 0.026
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.0425 0.077
AHNAK AHNAK: AHNAK protein 0.0425 0.026
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.0425 0.026
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.0425 0.060
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.0425 0.077
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.0425 0.032
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.026
ESPL1 N/A 0.0425 0.032
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.042 0.053
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.041 0.041
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.041 0.064
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.041 0.073
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.037
PHF10 N/A 0.040 0.113
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.040 36.10
TPR TPR: Nucleoprotein TPR 0.040 0.038
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.040 0.041
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.040 0.148
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.040 0.090
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.040 0.113
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.049
PRPH PRPH, NEF4, PRPH1: Peripherin 0.039 0.026
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.038 0.110
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.038 0.038
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.029
THOP1 THOP1: Thimet oligopeptidase 0.038 0.086
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.038 0.029
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.171
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.038 0.038
CHP CHP: Calcium-binding protein p22 0.038 0.035
SYMPK SYMPK, SPK: Symplekin 0.038 0.029
MYO1F MYO1F: Myosin-If 0.038 1.17
WASF2 WASF2, WAVE2: Wiskott-Aldrich syndrome protein family member 2 0.038 0.028
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.037 0.037
ATP2B1 N/A 0.037 0.032
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.081
GRIN2B GRIN2B, NMDAR2B: Glutamate [NMDA] receptor subunit epsilon-2 precursor 0.037 0.033
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.036 0.036
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.081
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.036 0.0453
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.036 0.100
LILRB1 N/A 0.036 0.126
TGIF2 TGIF2: Homeobox protein TGIF2 0.036 0.046
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.036 0.081
IRF3 IRF3: Interferon regulatory factor 3 0.036 0.030
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.036 0.126
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.036 0.044
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.036 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.036 0.044
SOS2 SOS2: Son of sevenless homolog 2 0.035 0.029
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
MAL2 MAL2: Protein MAL2 0.034 0.049
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.033 0.064
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.033 0.073
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.033 0.073
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.029
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.033 0.033
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.033 0.027
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.033 0.064
RAB27B RAB27B: Ras-related protein Rab-27B 0.033 0.076
PRLR PRLR: Prolactin receptor precursor 0.033 0.100
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.033 0.081
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.033 0.100
ETV1 ETV1, ER81: ETS translocation variant 1 0.033 0.0263
MET MET: Hepatocyte growth factor receptor precursor 0.033 0.081
GRIN2A GRIN2A, NMDAR2A: Glutamate [NMDA] receptor subunit epsilon-1 precursor 0.033 0.029
ITGB4 N/A 0.032 0.072
F3 F3: Tissue factor precursor 0.032 0.032
EGF EGF: Pro-epidermal growth factor precursor 0.032 0.032
KRT18 KRT18: Uncharacterized protein KRT18 0.032 0.072
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.072
IREB2 IREB2: Iron-responsive element-binding protein 2 0.032 0.026
STX7 STX7: Syntaxin-7 0.032 0.043
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.032 0.090
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.032 0.029
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.032 0.041
GJA5 GJA5: Gap junction alpha-5 protein 0.030 0.038
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.030 0.0338
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.030 0.0338
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.030 0.062
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.030 0.030
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.030 0.030
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.030 0.030
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.073
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.029 0.064
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.029 0.081
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.029 0.072
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.029 0.027
INSR INSR: Insulin receptor precursor 0.029 0.073
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.029 0.029
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.029 0.029
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.029 0.064
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.029 0.041
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.029 0.038
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.029 0.0308
ACTN1 ACTN1: Alpha-actinin-1 0.029 0.035
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.029 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.052
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.052
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.083
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.028 0.025
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.028
PHLDB2 N/A 0.028 0.028
C9orf88 N/A 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
MATK 0.028 0.028
CDC42 N/A 0.028 0.028
NCF4 N/A 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
CACNB2 N/A 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
PTPN7 N/A 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.028
PPEF1 N/A 0.028 0.052
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
DYRK4 DYRK4: Dual specificity tyrosine-phosphorylation-regulated kinase 4 0.028 0.060
SAR1B SAR1B, SARA2, SARB: GTP-binding protein SAR1b 0.028 0.036
PHKG2 PHKG2: Phosphorylase b kinase gamma catalytic chain, testis/liver isoform 0.028 0.036
ARL11 ARL11, ARLTS1: ADP-ribosylation factor-like protein 11 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
PSD3 N/A 0.027 0.027
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
ANKK1 ANKK1, PKK2, SGK288: Ankyrin repeat and protein kinase domain-containing protein 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
OSBPL9 N/A 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
PTPN13 N/A 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
RAB7B RAB7B: Ras-related protein Rab-7b 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
PDIK1L PDIK1L, CLIK1L: Serine/threonine-protein kinase PDIK1L 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
FAM43A N/A 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.027 0.037
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.027 0.126
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.027 0.100
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.027 0.100
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.027 0.030
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.027 0.081
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.027 0.100
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.027 0.030
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.0263 0.032
KCNJ1 KCNJ1, ROMK1: ATP-sensitive inward rectifier potassium channel 1 0.0263 0.0263
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0263 0.037
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.0263 0.037
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.026 0.064
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.026 0.058
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.026 0.064
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.026 0.064
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.026 0.064
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.026 0.064
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.026 0.065
MCOLN1 MCOLN1, ML4, MSTP080: Mucolipin-1 0.026 0.041
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.0794
CFL2 CFL2: Cofilin-2 0.025 0.025
BCR N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
SCRIB N/A 0.025 0.025
CASP7 N/A 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.047
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
CAMK2A N/A 0.025 0.025
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.047
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
CAMKK1 N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
EPN2 N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.148
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.075
BCOR N/A 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.047
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.075
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.075
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.025
NIPBL N/A 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.148
PRKCB1 N/A 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
RAC1 N/A 0.025 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.148
GRK6 N/A 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
SVIL SVIL: Supervillin 0.025 0.047
DBNL N/A 0.025 0.025
0.299
Total Score 10.30