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Evidence of Interaction Between RAF1 and EGF

The interaction score between RAF1 and EGF is 2.94.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between RAF1 and EGF = -0.08

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology N/A N/A
Domains Domains present in RAF1 and EGF:
Domains in RAF1Domains in EGF
IPR000719 Protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding
IPR003116 Raf-like Ras-binding
IPR000152 Aspartic acid and asparagine hydroxylation site
IPR001881 EGF-like calcium-binding
IPR006209 EGF-like domain
IPR006210 Type I EGF
IPR009030 Growth factor, receptor
IPR000033 Low-density lipoprotein receptor, YWTD repeat
IPR001336 Type I EGF subtype
IPR000742 EGF_2.
IPR013032 IPR006209.
IPR013091 EGF_Ca_bd_2.

The Chi square scores for co-occurrence of domains that are present in RAF1 and EGF are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR001881 EGF-like calcium-binding 47.2573
IPR008271 Serine/threonine protein kinase, active site IPR006209 EGF-like domain 46.8567
IPR000719 Protein kinase IPR000152 Aspartic acid and asparagine hydroxylation site 46.1111
IPR000719 Protein kinase IPR000742 EGF_2. 45.671
IPR000719 Protein kinase IPR006209 EGF-like domain 42.2895
IPR008271 Serine/threonine protein kinase, active site IPR000742 EGF_2. 41.0162
IPR011009 Protein kinase-like IPR006209 EGF-like domain 34.7413
IPR011009 Protein kinase-like IPR000742 EGF_2. 33.7818
IPR000719 Protein kinase IPR006210 Type I EGF 31.8195
IPR008271 Serine/threonine protein kinase, active site IPR006210 Type I EGF 30.3846
IPR011009 Protein kinase-like IPR001881 EGF-like calcium-binding 29.8435
IPR000719 Protein kinase IPR013032 IPR006209. 29.2885
IPR011009 Protein kinase-like IPR000152 Aspartic acid and asparagine hydroxylation site 29.1024
IPR008271 Serine/threonine protein kinase, active site IPR013032 IPR006209. 28.1386
IPR011009 Protein kinase-like IPR006210 Type I EGF 26.1393
IPR000719 Protein kinase IPR013091 EGF_Ca_bd_2. 22.594
IPR011009 Protein kinase-like IPR013032 IPR006209. 20.8081
IPR008271 Serine/threonine protein kinase, active site IPR009030 Growth factor, receptor 15.0295
IPR000719 Protein kinase IPR009030 Growth factor, receptor 9.05268
IPR011009 Protein kinase-like IPR009030 Growth factor, receptor 8.51938
IPR000719 Protein kinase IPR001336 Type I EGF subtype 8.40749
IPR011009 Protein kinase-like IPR001336 Type I EGF subtype 2.73616
IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding IPR009030 Growth factor, receptor 0.0636933

The background colour of the table refers to:

  • Blue Domain is only present in RAF1
  • Yellow Domain is only present in EGF
  • Green Domain is present in both RAF1 and EGF

 0.049
Post-translational Modifications

Protein: RAF1

PTMResidueReference
Dephosphorylation 340 PubMed, HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 43 PubMed, HPRD
Phosphorylation 233 PubMed, HPRD
Phosphorylation 259 PubMed, HPRD
Phosphorylation 268 PubMed, HPRD
Phosphorylation 269 PubMed, HPRD
Phosphorylation 289 PubMed, HPRD
Phosphorylation 296 PubMed, HPRD
Phosphorylation 301 PubMed, HPRD
Phosphorylation 338 PubMed, HPRD
Phosphorylation 339 PubMed, HPRD
Phosphorylation 340 PubMed, HPRD
Phosphorylation 341 PubMed, HPRD
Phosphorylation 491 PubMed, HPRD
Phosphorylation 494 PubMed, HPRD
Phosphorylation 499 PubMed, HPRD
Phosphorylation 621 PubMed, HPRD
Phosphorylation 642 PubMed, HPRD
Phosphoserine 43 HPRD
Phosphoserine 259 PubMed, HPRD
Phosphoserine 338 PubMed, HPRD
Phosphoserine 499 PubMed, HPRD
Phosphoserine 621 HPRD
Phosphothreonine 268 PubMed, HPRD

Protein: EGF

PTMResidueReference
Proteolytic Cleavage 1022 PubMed, HPRD
Localisation

Protein: RAF1

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD

Protein: EGF

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Transitive Score

The common interactors between RAF1 and EGF that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between RAF1 andEGF. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , RAF1 has 1538 interactors and EGF has 1076 interactors of which there are 511 common interactors.

Common InteractorName of Common InteractorScore for RAF1-Interactor (?)Score for EGF-Interactor (?)
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 501.00 0.049
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 82.20 0.029
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 23.50 0.033
GP5 GP5: Platelet glycoprotein V precursor 1.15 0.048
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.852 0.029
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.763 0.072
MSN MSN: Moesin 0.763 0.072
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.763 0.032
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.763 0.029
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.763 0.029
STAT6 STAT6: Signal transducer and activator of transcription 6 0.763 0.072
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.763 0.072
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.763 0.072
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.763 0.032
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.515 0.081
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.515 0.072
VASP VASP: Vasodilator-stimulated phosphoprotein 0.515 0.072
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.503 0.045
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.461 0.065
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.461 0.072
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.461 0.029
SYK SYK: Tyrosine-protein kinase SYK 0.461 0.072
STK10 STK10: Uncharacterized protein STK10 0.461 0.032
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.461 0.072
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.072
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.461 0.032
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.461 0.072
LYN LYN: Tyrosine-protein kinase Lyn 0.461 0.072
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.461 0.032
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.461 0.072
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.461 0.072
PSCD4 PSCD4, CYT4: Cytohesin-4 0.461 0.072
CSK CSK: Tyrosine-protein kinase CSK 0.461 0.065
HCK N/A 0.461 0.072
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.416 0.029
ROCK1 ROCK1: Rho-associated protein kinase 1 0.416 0.072
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.385 0.032
GMIP GMIP: GEM-interacting protein 0.385 0.032
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.385 0.0263
RPS6KB1 N/A 0.372 0.072
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.372 0.065
NCK2 NCK2: Cytoplasmic protein NCK2 0.372 0.065
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.372 0.032
CRKL CRKL: Crk-like protein 0.372 0.065
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.372 0.033
DOK1 DOK1: Docking protein 1 0.372 0.072
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.372 0.032
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.029
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.372 0.072
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.372 0.065
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.372 0.072
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.372 0.072
JAK1 0.372 0.065
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.372 0.029
PLEK PLEK, P47: Pleckstrin 0.340 0.045
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.340 0.045
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.318 0.032
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.307 0.029
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.307 0.072
GAB2 N/A 0.307 0.029
VIL2 N/A 0.275 0.072
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.275 0.032
CDK2 CDK2: Cell division protein kinase 2 0.275 0.032
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.275 0.037
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.275 0.072
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.275 0.029
CDK4 CDK4: Cell division protein kinase 4 0.275 0.032
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.275 0.037
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.275 0.100
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.275 0.026
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.275 0.026
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.260 0.072
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.260 0.065
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.0263
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.251 0.032
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.251 0.072
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.065
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.251 0.029
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.251 0.072
STK16 N/A 0.251 0.029
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.072
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.251 0.072
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.251 0.032
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.233 0.032
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.233 0.072
CXorf9 N/A 0.233 0.032
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.233 0.032
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.225 0.032
CDK7 CDK7, MO15: Cell division protein kinase 7 0.225 0.029
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.225 0.081
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.072
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.225 0.032
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.225 0.0727
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.225 0.072
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.225 0.081
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.225 0.072
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.210 0.032
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.191 0.026
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.191 0.081
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.191 0.026
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.188 0.049
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.188 0.029
TLN1 TLN1: Uncharacterized protein TLN1 0.188 0.029
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.188 0.032
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.188 0.072
SOS1 SOS1: Son of sevenless homolog 1 0.181 0.045
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.032
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.171 0.029
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.171 0.032
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.171 0.029
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.072
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.171 0.072
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.171 0.037
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.171 0.062
STAT2 STAT2: Signal transducer and activator of transcription 2 0.166 0.051
MAPK15 N/A 0.165 0.109
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.165 0.049
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.049
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.044
PSCD2 N/A 0.165 0.109
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.109
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.049
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.109
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.165 0.049
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.109
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.109
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.044
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.049
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.165 0.049
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.109
NF2 NF2, SCH: Merlin 0.165 0.109
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.044
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.155 0.072
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.155 0.029
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.155 0.0453
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.153 0.055
CD44 N/A 0.153 0.109
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.153 0.055
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.152 0.072
PRKAA1 N/A 0.152 0.032
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.152 0.032
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.072
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.152 0.029
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.081
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.148 0.049
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.148 0.049
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.148 0.044
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.109
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.109
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.148 0.049
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.109
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.049
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.049
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.109
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.109
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.148 0.044
ELMO1 N/A 0.148 0.109
CDC2 CDC2: Cell division control protein 2 homolog 0.148 0.049
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.049
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.109
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.148 0.083
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.109
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.109
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.109
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.109
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.109
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.049
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.109
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.049
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.049
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.148 0.049
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.049
ARHGEF7 N/A 0.148 0.049
STAT3 0.148 0.044
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.148 0.049
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.148 0.049
ATM ATM: Serine-protein kinase ATM 0.139 0.032
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.139 0.072
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.139 0.029
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.139 0.081
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.032
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.137 0.109
RIN1 RIN1: Ras and Rab interactor 1 0.136 0.029
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.136 0.072
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.136 0.072
PLD2 PLD2: Phospholipase D2 0.136 0.072
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.136 0.072
RASA3 RASA3: Ras GTPase-activating protein 3 0.136 0.029
APS SH2B2, APS: SH2B adapter protein 2 0.136 0.072
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.136 0.032
CDK5 CDK5: Cell division protein kinase 5 0.136 0.029
LCP1 LCP1, PLS2: Plastin-2 0.129 0.032
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.129 0.029
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.127 0.029
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.127 0.032
CIITA CIITA, MHC2TA: MHC class II transactivator 0.127 0.0263
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.126 0.0416
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.055
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.124 0.109
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.100
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.123 0.081
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.123 0.032
GRLF1 N/A 0.123 0.032
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.114 0.032
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.114 0.029
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.037
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.113 0.062
DAB2 DAB2, DOC2: Disabled homolog 2 0.110 0.100
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.110 0.0453
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.110 0.072
RDX RDX: Radixin 0.110 0.065
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.110 0.029
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.110 0.037
PLD1 PLD1: Phospholipase D1 0.110 0.081
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.110 0.032
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.110 0.029
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.110 0.072
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.165
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.109 0.083
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.083
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.109 0.083
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.109 0.165
IRS1 IRS1: Insulin receptor substrate 1 0.109 0.081
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.109 0.037
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.109 0.037
BMX N/A 0.109 0.081
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.109 0.072
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.099 0.037
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.099 0.152
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.099 0.032
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.099 0.100
MYO3A MYO3A: Myosin IIIA 0.099 0.037
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.099 0.0453
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.099 0.072
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.098 0.072
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.098 0.100
MCF2 MCF2, DBL: Proto-oncogene DBL 0.098 0.029
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.098 0.0688
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.098 0.034
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.098 0.0688
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.098 0.034
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.165
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.083
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.098 0.028
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.098 0.034
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.028
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.097 0.032
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.097 0.072
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.097 0.081
PSD TYL: TYL protein 0.097 0.065
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.097 0.081
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.097 0.100
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.097 0.049
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.097 0.0453
STAT4 STAT4: Signal transducer and activator of transcription 4 0.090 0.045
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.088 0.029
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.088 0.072
DAB1 DAB1: Disabled homolog 1 0.088 0.072
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.088 0.065
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.088 0.072
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.088 0.029
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.072
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.088 0.072
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.087 0.072
FUBP1 N/A 0.087 0.026
WEE1 WEE1: Wee1-like protein kinase 0.086 0.032
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.086 0.032
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.086 0.029
STAM2 STAM2: Signal transducing adapter molecule 2 0.086 0.032
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.086 0.032
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.086 0.029
MAPKAPK5 N/A 0.083 0.049
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.04
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.049
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.04
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.049
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.083 0.049
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.0818 0.055
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.0818 0.109
CENTA1 CENTA1: Centaurin-alpha 1 0.0794 0.041
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.078 0.072
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.078 0.029
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.032
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.077 0.032
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.077 0.065
DAPK2 DAPK2: Death-associated protein kinase 2 0.077 0.037
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.072
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.075 0.109
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.109
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.049
GIT2 N/A 0.075 0.049
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.049
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.04
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.04
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.075 0.049
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.049
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.075 0.049
MYO18A 0.075 0.049
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.04
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.074 0.055
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.074 0.109
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.074 0.109
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.074 0.109
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.074 0.055
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.074 0.055
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.073 0.051
GABRR1 N/A 0.0727 0.032
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.072 0.025
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.072 0.051
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.072 0.026
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.072 0.051
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.070 0.029
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.070 0.032
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.069 0.029
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.067 0.123
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.067 0.077
ITGB7 ITGB7: Integrin beta-7 precursor 0.067 0.109
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.066 0.029
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.065 0.077
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.064 0.037
PTPRZ1 N/A 0.064 0.049
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.055
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.064 0.041
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.064 0.051
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.064 0.152
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.063 0.037
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.063 0.026
PREP PREP, PEP: Prolyl endopeptidase 0.063 0.0727
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.063 0.032
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.062
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.058 0.026
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.123
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.058 0.077
GLRA1 N/A 0.058 0.032
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.057 0.055
EPOR EPOR: Erythropoietin receptor precursor 0.057 0.055
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.057 0.055
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.057 0.055
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.056 0.049
SORBS3 SORBS3, SCAM1: Vinexin 0.056 0.0263
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.056 0.0453
MT3 MT3: Metallothionein-3 0.056 0.033
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.056 0.0263
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.056 0.0263
CTTN CTTN, EMS1: Src substrate cortactin 0.056 0.030
DES DES: Desmin 0.055 0.030
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.054 0.029
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.053 0.038
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.052 0.032
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.052 0.065
GRB10 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.051 0.072
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.051 0.037
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.051 0.037
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.051 0.123
KIT KIT: Mast/stem cell growth factor receptor precursor 0.051 0.109
TLN2 TLN2: Uncharacterized protein TLN2 0.050 0.126
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.037
NEFH NEFH, KIAA0845, NFH: Neurofilament heavy polypeptide 0.049 0.030
SPTAN1 N/A 0.049 0.029
CNN3 CNN3: Calponin-3 0.049 0.0453
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.049 0.165
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.049 0.028
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.165
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.083
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.056
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.083
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.028
GPRC5A GPRC5A, GPCR5A, RAI3, RAIG1: Retinoic acid-induced protein 3 0.049 0.028
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.049 0.028
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.028
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.083
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.083
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.083
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.083
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.049 0.165
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.049 0.032
AQP1 AQP1, CHIP28: Aquaporin-1 0.049 0.027
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.049 0.037
PARD3 N/A 0.049 0.037
APEH APEH, D3F15S2, D3S48E, DNF15S2: Acylamino-acid-releasing enzyme 0.046 0.029
MDN1 MDN1, KIAA0301: Midasin 0.046 0.029
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.051
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.046 0.072
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.046 0.072
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.046 0.037
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.0453 0.077
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.0453 0.055
GHR GHR: Growth hormone receptor precursor 0.0453 0.062
CGA CGA: Glycoprotein hormones alpha chain precursor 0.045 0.032
FSHB FSHB: Follitropin subunit beta precursor 0.045 0.072
LHB LHB: Lutropin subunit beta precursor 0.045 0.072
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.0446 0.055
SORL1 SORL1: Sortilin-related receptor precursor 0.0446 0.109
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.0446 0.055
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.081
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.044 0.029
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.044 0.037
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.029
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.044 0.028
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.044 0.165
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.044 0.165
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.083
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.044 0.165
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.044 0.165
AQP4 AQP4: Aquaporin-4 0.044 0.028
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.083
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.165
FGF9 FGF9: Glia-activating factor precursor 0.041 0.037
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.041 0.057
TSHB TSHB: Thyrotropin subunit beta precursor 0.041 0.072
INHA INHA: Inhibin alpha chain precursor 0.041 0.0263
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.041 0.152
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.041 0.123
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.041 0.0263
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.041 0.072
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.072
TBXA2R TBXA2R: Thromboxane A2 receptor 0.04 0.028
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.04 0.028
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.04 0.028
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.04 0.028
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.04 0.028
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.04 0.028
DRD2 DRD2: D(2) dopamine receptor 0.04 0.028
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.040 0.109
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.040 0.062
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.040 0.109
NOS1 NOS1: Nitric-oxide synthase, brain 0.040 0.057
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.057
PRPH PRPH, NEF4, PRPH1: Peripherin 0.039 0.030
F5 F5: Coagulation factor V precursor 0.039 0.081
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.038 0.033
THOP1 THOP1: Thimet oligopeptidase 0.038 0.065
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.037 0.026
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.062
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.037 0.081
NDP NDP: Norrin precursor 0.036 0.037
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.049
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.036 0.123
ITGAE ITGAE: Integrin alpha-E precursor 0.036 0.098
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.036 0.055
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.036 0.098
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.036 0.098
XRCC1 XRCC1: DNA-repair protein XRCC1 0.036 0.045
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.036 0.062
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.036 0.028
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.036 0.028
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.049
TRHR TRHR: Thyrotropin-releasing hormone receptor 0.033 0.026
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.033 0.191
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.033 1.50
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.033 0.0416
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.033 0.109
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.055
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.033 0.123
PRLR PRLR: Prolactin receptor precursor 0.033 0.077
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.033 0.152
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.033 0.062
MET MET: Hepatocyte growth factor receptor precursor 0.033 0.123
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.032 0.123
ITGB4 N/A 0.032 0.123
F3 F3: Tissue factor precursor 0.032 0.055
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.123
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.062
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.032 0.123
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.032 0.039
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.030 0.044
F2R F2R, CF2R, PAR1, TR: Proteinase-activated receptor 1 precursor 0.030 0.026
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.123
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.029 0.123
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.029 0.062
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.029 0.191
RHO RHO, OPN2: Rhodopsin 0.029 0.032
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.123
INSR INSR: Insulin receptor precursor 0.029 0.123
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.029 0.062
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.029 0.062
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.029 0.152
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 0.029 0.031
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.029 0.191
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.029 0.033
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.049
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.049
TSHR N/A 0.027 0.039
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.027 0.077
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.027 0.062
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.027 0.055
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.027 0.109
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.027 0.034
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.027 0.055
F2RL3 F2RL3, PAR4: Proteinase-activated receptor 4 precursor 0.0263 0.026
KCNJ1 KCNJ1, ROMK1: ATP-sensitive inward rectifier potassium channel 1 0.0263 0.144
MC4R MC4R: Melanocortin receptor 4 0.0263 0.026
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0263 0.123
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.026 0.123
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.026 0.109
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.026 0.123
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.026 0.098
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.026 0.109
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.026 0.152
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.026 0.109
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.0453
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.109
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.04
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.109
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.049
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.109
0.228
Total Score 2.94