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Evidence of Interaction Between KIT and ATP2A2

The interaction score between KIT and ATP2A2 is 17.10.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismKIT OrthologueATP2A2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00018335 0.132 IPI00303760 0.214
human IPI00021396 0.132 IPI00303760 0.214
worm O76698 0.132 Q9XTG6 1
worm Q21038 0.132 Q9XTG6 1
worm Q21041 0.132 Q9XTG6 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.22E-3
Domains No domains were used in calculating likelihood of interaction 0.083
Post-translational Modifications

Protein: KIT

PTMResidueReference
Dephosphorylation 570 PubMed, HPRD
N-linked 130 PubMed, HPRD
Phosphorylation 545 PubMed, HPRD
Phosphorylation 547 PubMed, HPRD
Phosphorylation 553 PubMed, HPRD
Phosphorylation 568 PubMed, HPRD
Phosphorylation 570 PubMed, HPRD
Phosphorylation 703 PubMed, HPRD
Phosphorylation 721 PubMed, HPRD
Phosphorylation 730 PubMed, HPRD
Phosphorylation 741 PubMed, HPRD
Phosphorylation 746 PubMed, HPRD
Phosphorylation 747 PubMed, HPRD
Phosphorylation 821 PubMed, HPRD
Phosphorylation 900 PubMed, HPRD
Phosphorylation 936 PubMed, HPRD
Phosphorylation 959 PubMed, HPRD

Protein: ATP2A2

PTMResidueReference
Phosphorylation 38 PubMed, HPRD
Phosphorylation 663 PubMed, HPRD
Phosphoserine 663 HPRD
Localisation

Protein: KIT

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD

Protein: ATP2A2

LocalisationReference
ER HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between KIT and ATP2A2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between KIT andATP2A2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , KIT has 1344 interactors and ATP2A2 has 735 interactors of which there are 585 common interactors.

Common InteractorName of Common InteractorScore for KIT-Interactor (?)Score for ATP2A2-Interactor (?)
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 487.00 0.044
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 422.00 0.044
CRKL CRKL: Crk-like protein 388.00 0.044
NCK2 NCK2: Cytoplasmic protein NCK2 315.00 0.044
STAT5B STAT5B: Signal transducer and activator of transcription 5B 214.00 0.030
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 127.00 0.047
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 112.00 0.075
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 46.80 0.075
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 46.80 0.075
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 43.20 0.044
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 35.00 0.098
GNAI1 GNAI1: Guanine nucleotide-binding protein G(i), alpha-1 subunit 11.10 0.025
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 11.10 0.025
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 8.99 0.025
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 0.049
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.049
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.109
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 0.098
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 0.049
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 0.098
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.049
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.902 0.098
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.902 0.044
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.902 0.049
SYK SYK: Tyrosine-protein kinase SYK 0.902 0.044
STAT3 0.878 0.044
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.878 0.044
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.808 0.044
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.808 0.044
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 0.044
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.808 0.044
ITGA2B ITGA2B, GP2B, ITGAB: Integrin alpha-IIb precursor 0.763 0.025
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.731 0.049
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 0.049
JAK1 0.731 0.044
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.731 0.049
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.731 0.049
RIN1 RIN1: Ras and Rab interactor 1 0.655 0.044
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 0.044
CSK CSK: Tyrosine-protein kinase CSK 0.655 0.044
VAV1 VAV1, VAV: Proto-oncogene vav 0.655 0.098
BMX N/A 0.654 0.109
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 0.044
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.109
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.644 0.049
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.644 0.049
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.644 0.109
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.644 0.049
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
GRB10 N/A 0.617 0.051
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 0.049
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.577 0.044
STAT6 STAT6: Signal transducer and activator of transcription 6 0.577 0.044
LYN LYN: Tyrosine-protein kinase Lyn 0.577 0.044
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.577 0.044
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.577 0.044
APS SH2B2, APS: SH2B adapter protein 2 0.577 0.098
HCK N/A 0.577 0.044
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.577 0.044
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.553 0.046
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.520 0.098
STAT2 STAT2: Signal transducer and activator of transcription 2 0.497 0.034
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.484 0.030
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.403 0.034
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.361 0.030
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.034
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.318 0.030
STAT4 STAT4: Signal transducer and activator of transcription 4 0.318 0.030
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.307 0.028
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.275 0.075
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.191 0.028
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.191 0.028
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.028
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.181 0.044
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.171 0.025
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.171 0.075
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.166 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.083
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.028
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.028
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.028
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.028
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.028
FN1 N/A 0.165 0.028
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.083
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.165 0.028
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.028
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.028
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.028
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.028
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.028
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.028
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.028
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.028
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.083
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.028
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.028
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.028
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.028
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.028
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.028
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.028
KIR3DL1 N/A 0.165 0.028
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.075
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.152 0.028
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.152 0.083
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.152 0.028
ITGAE ITGAE: Integrin alpha-E precursor 0.152 0.028
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.152 0.028
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.152 0.028
EPOR EPOR: Erythropoietin receptor precursor 0.152 0.028
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.152 0.028
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.152 0.028
PTPRZ1 N/A 0.152 0.025
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.152 0.028
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.148 0.098
ATRN N/A 0.148 0.025
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.025
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.148 0.025
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.025
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.075
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.075
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.025
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.025
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.025
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.025
BSG N/A 0.148 0.025
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.075
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.025
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.136 0.025
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.136 0.025
ITGAV ITGAV, MSK8, VNRA: Integrin alpha-V precursor 0.136 0.025
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.136 0.025
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.127 0.028
GAB2 N/A 0.126 0.109
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.123 0.028
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.123 0.028
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.123 0.075
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.028
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.123 0.028
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.123 0.083
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.028
SELE SELE, ELAM1: E-selectin precursor 0.123 0.028
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.123 0.028
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.123 0.028
CD69 CD69: Early activation antigen CD69 0.123 0.028
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.123 0.028
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.123 0.028
KEL KEL: Kell blood group glycoprotein 0.123 0.028
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.028
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.123 0.028
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.123 0.028
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.123 0.028
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.123 0.028
SORL1 SORL1: Sortilin-related receptor precursor 0.123 0.028
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.123 0.028
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.123 0.083
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.123 0.028
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.028
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.123 0.028
F10 F10: Coagulation factor X precursor 0.123 0.025
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.113 0.098
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.113 0.044
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.110 0.025
DCC DCC: Netrin receptor DCC precursor 0.110 0.025
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.110 0.075
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.110 0.075
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.110 0.075
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.110 0.075
INSR INSR: Insulin receptor precursor 0.110 0.075
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.110 0.025
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.110 0.025
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.025
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.049
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.109
NF2 NF2, SCH: Merlin 0.109 0.109
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.044
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.109
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.049
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.109
PSCD2 N/A 0.109 0.109
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.044
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.028
F3 F3: Tissue factor precursor 0.109 0.028
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.028
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.109 0.028
EGF EGF: Pro-epidermal growth factor precursor 0.109 0.028
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.028
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.083
GHR GHR: Growth hormone receptor precursor 0.109 0.028
PVR PVR, PVS: Poliovirus receptor precursor 0.109 0.028
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.109 0.028
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.109 0.028
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.028
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, testis-specific isoform precursor 0.109 0.028
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.109 0.028
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.028
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.109 0.028
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.109 0.028
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.109 0.028
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.109 0.028
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.028
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.109 0.028
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.109 0.025
LILRB1 N/A 0.109 0.028
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.109 0.028
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.109 0.028
ITGB4 N/A 0.109 0.028
CRLF3 N/A 0.109 0.028
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.028
PRLR PRLR: Prolactin receptor precursor 0.109 0.028
MME MME, EPN: Neprilysin 0.109 0.028
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.098 0.028
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.098 0.028
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.028
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.028
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.098 0.028
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.098 0.028
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.098 0.028
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.098 0.028
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.098 0.028
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.098 0.028
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.028
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.028
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.098 0.028
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.098 0.028
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.098 0.028
ELMO1 N/A 0.098 0.098
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.098
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.044
ARHGEF7 N/A 0.098 0.098
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.098
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.044
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.098
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.044
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 0.044
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.098
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.044
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.098
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.098
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.044
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.044
MEP1B MEP1B: Meprin A subunit beta precursor 0.097 0.025
ITGA3 ITGA3, MSK18: Integrin alpha-3 precursor 0.097 0.025
SFRP1 CDNA FLJ45402 fis, clone BRHIP3029409, moderately similar to Homo sapiens secret 0.097 0.025
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.097 0.075
ITGB7 ITGB7: Integrin beta-7 precursor 0.097 0.025
NEO1 NEO1, NGN: Neogenin precursor 0.097 0.025
ASGR1 ASGR1: Asialoglycoprotein receptor 1 0.097 0.025
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.025
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.097 0.025
CD63 CD63, MLA1, TSPAN30: CD63 antigen 0.097 0.025
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.097 0.148
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.097 0.025
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.075
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.075
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.097 0.075
CD151 CD151, TSPAN24: CD151 antigen 0.097 0.025
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.097 0.075
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.097 0.075
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.097 0.075
MEP1A MEP1A: Meprin A subunit alpha precursor 0.097 0.025
TNC TNC, HXB: Tenascin precursor 0.097 0.025
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.096 0.083
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.096 0.028
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.096 0.028
SOS1 SOS1: Son of sevenless homolog 1 0.094 0.062
CDK6 CDK6: Cell division protein kinase 6 0.091 0.044
RDX RDX: Radixin 0.090 0.098
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.090 0.098
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.090 0.044
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.090 0.098
CD2AP CD2AP: CD2-associated protein 0.090 0.044
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.098
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.090 0.098
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.090 0.098
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.098
DOK1 DOK1: Docking protein 1 0.090 0.098
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.090 0.098
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.090 0.098
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.090 0.098
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.088 0.025
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.088 0.075
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.086 0.075
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.083 0.028
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.028
EDA N/A 0.083 0.028
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.083 0.028
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.028
DLK1 DLK1, DLK: Delta-like protein precursor 0.083 0.028
OPTC OPTC, OPT: Opticin precursor 0.083 0.028
PCDHA2 PCDHA2: Protocadherin alpha 2 precursor 0.083 0.028
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.028
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.083 0.028
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.028
CDH6 CDH6: Cadherin-6 precursor 0.083 0.028
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.028
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.028
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.083 0.028
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.083 0.028
ROCK1 ROCK1: Rho-associated protein kinase 1 0.081 0.109
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.081 0.049
GAB1 GAB1: GRB2-associated-binding protein 1 0.081 0.109
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.081 0.044
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 0.049
IRS1 IRS1: Insulin receptor substrate 1 0.081 0.109
SPTAN1 N/A 0.081 0.049
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.081 0.109
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.109
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.081 0.044
ATP2B1 N/A 0.077 0.028
GP1BA N/A 0.077 0.028
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.077 0.028
FADD FADD, MORT1: Protein FADD 0.077 0.028
DSG2 DSG2: Desmoglein-2 precursor 0.077 0.028
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.075 0.036
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.075
JAG2 JAG2: Jagged-2 precursor 0.075 0.025
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.025
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.025
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.073 0.098
DLG2 DLG2: Disks large homolog 2 0.073 0.044
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.073 0.098
PSD TYL: TYL protein 0.073 0.098
MSN MSN: Moesin 0.073 0.098
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.073 0.044
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.073 0.098
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.073 0.044
FNBP1 N/A 0.073 0.044
PLD2 PLD2: Phospholipase D2 0.073 0.098
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.073 0.044
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.073 0.098
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.073 0.098
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.073 0.098
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.073 0.098
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.073 0.098
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.072 0.049
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.109
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.109
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.049
VASP VASP: Vasodilator-stimulated phosphoprotein 0.072 0.109
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.072 0.049
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.069 0.075
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.067 0.044
CDK4 CDK4: Cell division protein kinase 4 0.067 0.044
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.067 0.044
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.067 0.044
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.065 0.109
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.065 0.049
DAB1 DAB1: Disabled homolog 1 0.064 0.098
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.044
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.044
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.064 0.098
SORBS3 SORBS3, SCAM1: Vinexin 0.064 0.044
PSCD4 PSCD4, CYT4: Cytohesin-4 0.064 0.098
CXorf9 N/A 0.064 0.044
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.064 0.098
VIL2 N/A 0.064 0.098
RASA3 RASA3: Ras GTPase-activating protein 3 0.064 0.098
DAB2 DAB2, DOC2: Disabled homolog 2 0.064 0.098
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.063 0.0688
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.062 0.028
CDH5 CDH5: Cadherin-5 precursor 0.062 0.028
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.062 0.028
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.062 0.028
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.062 0.028
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.062 0.028
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.058 0.044
PLD1 PLD1: Phospholipase D1 0.058 0.098
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.058 0.044
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.057 0.044
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.056 0.025
GLRB GLRB: Glycine receptor subunit beta precursor 0.056 0.025
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.056 0.025
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.056 0.025
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.025
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.056 0.025
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.056 0.025
NOTCH4 N/A 0.056 0.025
CDH17 CDH17: Cadherin-17 precursor 0.055 0.028
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.055 0.028
CDH2 CDH2, CDHN, NCAD: Cadherin-2 precursor 0.055 0.028
GP9 GP9: Platelet glycoprotein IX precursor 0.055 0.028
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.055 0.028
HPN HPN, TMPRSS1: Serine protease hepsin 0.055 0.025
RHO RHO, OPN2: Rhodopsin 0.055 0.028
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.055 0.028
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.055 0.028
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.055 0.028
CD44 N/A 0.055 0.028
TLR4 TLR4: Toll-like receptor 4 precursor 0.055 0.025
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.055 0.028
CDH13 CDH13, CDHH: Cadherin-13 precursor 0.055 0.028
UMOD UMOD: Uromodulin precursor 0.055 0.028
AREG AREG, SDGF: Amphiregulin precursor 0.055 0.028
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.055 0.028
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.052 0.028
TBXA2R TBXA2R: Thromboxane A2 receptor 0.052 0.028
NPR3 NPR3, ANPRC: Atrial natriuretic peptide clearance receptor precursor 0.052 0.028
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.052 0.028
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
C9orf88 N/A 0.051 0.051
RAPH1 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PLEK PLEK, P47: Pleckstrin 0.051 0.0688
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.051 0.062
CENTA1 CENTA1: Centaurin-alpha 1 0.051 0.0688
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.051 0.044
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.051 0.036
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.051 0.044
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.051 0.044
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.051 0.044
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.051 0.044
DSG3 DSG3: Desmoglein-3 precursor 0.049 0.028
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.049 0.028
GABRR1 N/A 0.049 0.028
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.028
DSC2 DSC2, DSC3: Desmocollin-2 precursor 0.049 0.028
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.049 0.028
CCR5 CCR5: CCR5 receptor (Fragment) 0.049 0.028
PCDH7 PCDH7, BHPCDH: Protocadherin-7 precursor 0.049 0.028
MAPK15 N/A 0.049 0.049
MAP2K5 N/A 0.049 0.04
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.049
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.049
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.049 0.025
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.049 0.025
CSPG4 CSPG4, MCSP: Chondroitin sulfate proteoglycan 4 precursor 0.049 0.025
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.049 0.025
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.049 0.075
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.049 0.025
GP5 GP5: Platelet glycoprotein V precursor 0.049 0.025
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.025
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.049 0.025
GLRA1 N/A 0.049 0.025
TPBG TPBG, 5T4: Trophoblast glycoprotein precursor 0.049 0.025
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.049 0.025
AQP4 AQP4: Aquaporin-4 0.047 0.025
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.025
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.046 0.062
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.0453 0.049
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.0453 0.049
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0453 0.049
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.0453 0.049
WEE1 WEE1: Wee1-like protein kinase 0.0453 0.036
LDLR LDLR: Low-density lipoprotein receptor precursor 0.044 0.025
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.044 0.047
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.044
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.044
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.044
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.044
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.044
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.043 0.025
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.041 0.044
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.041 0.044
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.041 0.044
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.041 0.044
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.041 0.044
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.041 0.044
CDK2 CDK2: Cell division protein kinase 2 0.041 0.044
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.041 0.044
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.041 0.044
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.041 0.036
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.041 0.036
CDK5 CDK5: Cell division protein kinase 5 0.041 0.044
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.041 0.044
RPS6KB1 N/A 0.041 0.044
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.041 0.044
MYB MYB: Myb proto-oncogene protein 0.039 0.034
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.028
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 0.038 0.025
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.049
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.037 0.049
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.037 0.049
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.047
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.035 0.025
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.035 0.025
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.035 0.025
TNFRSF10C TNFRSF10C, DCR1, UNQ321/PRO366, LIT, TRAILR3, TRID: Tumor necrosis factor recept 0.034 0.028
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.028
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.034 0.028
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.034 0.028
SDC1 SDC1, SDC: Syndecan-1 precursor 0.034 0.028
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.034 0.046
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.033 0.044
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.033 0.044
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.033 0.044
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.033 0.044
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.033 0.044
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.033 0.044
STK10 STK10: Uncharacterized protein STK10 0.033 0.044
DYRK3 N/A 0.033 0.044
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.033 0.044
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.033 0.044
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.033 0.044
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.033 0.036
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.033 0.044
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.044
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.044
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.033 0.044
PRKAA1 N/A 0.032 0.049
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.032 0.044
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.049
STK16 N/A 0.032 0.049
CDKL5 N/A 0.032 0.049
GPR23 LPA4, GPR23, P2RY9: Lysophosphatidic acid receptor 4 0.032 0.028
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.031 0.028
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.0308 0.025
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.0308 0.025
SDC4 SDC4: Syndecan-4 precursor 0.0308 0.025
SLC4A1 SLC4A1, AE1, DI, EPB3: Band 3 anion transport protein 0.0308 0.025
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.046
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.046
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.030
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.030
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.029 0.049
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.029 0.036
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.029 0.044
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.044
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.029 0.044
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.029 0.044
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.029 0.044
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.044
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.029 0.044
CDK7 CDK7, MO15: Cell division protein kinase 7 0.029 0.044
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.044
MYO3A MYO3A: Myosin IIIA 0.029 0.044
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.044
KCNJ12 KCNJ12, IRK2, KCNJN1: ATP-sensitive inward rectifier potassium channel 12 0.029 0.025
TSHR N/A 0.029 0.025
DLG1 N/A 0.029 0.025
PCDH7 N/A 0.028 0.028
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.028 0.028
PILRA PILRA: Paired immunoglobulin-like type 2 receptor alpha precursor 0.028 0.028
CSF3R N/A 0.028 0.028
ITGB1 N/A 0.028 0.028
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
PTPRA N/A 0.028 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.028 0.028
C2orf7 PAP21, C2orf7, UNQ833/PRO1760: Protease-associated domain-containing protein of 0.028 0.025
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.028 0.028
LAIR1 LAIR1, CD305: Leukocyte-associated immunoglobulin-like receptor 1 precursor 0.028 0.028
TREML1 TREML1, TLT1, UNQ1825/PRO3438: Trem-like transcript 1 protein precursor 0.028 0.028
DRD2 DRD2: D(2) dopamine receptor 0.028 0.028
SNAP25 N/A 0.028 0.028
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.028
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.028
GPRC5A GPRC5A, GPCR5A, RAI3, RAIG1: Retinoic acid-induced protein 3 0.028 0.028
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.026 0.044
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.044
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.026 0.044
TFRC TFRC: Transferrin receptor protein 1 0.026 0.028
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.026 0.025
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 2 0.026 0.028
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.026 0.028
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.026 0.028
TFR2 TFR2, hCG_20451: Uncharacterized protein TFR2 0.026 0.028
DEAF1 DEAF1: Uncharacterized protein DEAF1 0.026 0.025
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.026 0.028
SPINT2 SPINT2, HAI2, KOP: Kunitz-type protease inhibitor 2 precursor 0.026 0.028
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.026 0.047
ATP1B1 N/A 0.025 0.025
SLC7A3 SLC7A3, ATRC3, CAT3: Cationic amino acid transporter 3 0.025 0.025
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.025 0.025
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.025 0.025
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.025 0.025
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.025 0.025
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.025
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.047
FGFR2 N/A 0.025 0.025
TMPRSS9 N/A 0.025 0.025
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.025 0.025
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.025
0.572
Total Score 17.10