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Evidence of Interaction Between STUB1 and RGS2

The interaction score between STUB1 and RGS2 is 1.9.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between STUB1 and RGS2 = 0.09

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology N/A N/A
Domains No domains were used in calculating likelihood of interaction 0.028
Post-translational Modifications

Protein: STUB1

PTMResidueReference
Phosphorylation 19 PubMed, HPRD
Phosphorylation 23 PubMed, HPRD
Phosphoserine 19 HPRD
Phosphoserine 23 HPRD

Protein: RGS2

PTMResidueReference
Phosphorylation 46 PubMed, HPRD
Phosphorylation 64 PubMed, HPRD
Localisation

Protein: STUB1

LocalisationReference
ER HPRD
Cytoplasm HPRD

Protein: RGS2

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between STUB1 and RGS2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between STUB1 andRGS2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , STUB1 has 748 interactors and RGS2 has 886 interactors of which there are 477 common interactors.

Common InteractorName of Common InteractorScore for STUB1-Interactor (?)Score for RGS2-Interactor (?)
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 4.64 0.028
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.385 0.096
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.275 0.032
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.275 0.032
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.225 0.026
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.171 0.0425
HSP90AA1 Hsp89-alpha-delta-N 0.171 0.026
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.171 0.026
GNAI2 Galphai2 protein 0.148 5.04
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 0.148 0.519
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.148 0.028
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.139 0.026
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.139 0.026
COPE COPE: Coatomer subunit epsilon 0.139 0.0425
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.136 0.032
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.136 0.026
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 2 0.126 0.581
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 0.126 0.644
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.126 1.48
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.118 0.062
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.114 0.026
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.114 0.026
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.114 0.032
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.113 2.46
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.098 0.980
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.090 0.091
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 0.090 1.48
GNA12 GNA12: Guanine nucleotide-binding protein alpha-12 subunit 0.090 0.731
GNAI1 GNAI1: Guanine nucleotide-binding protein G(i), alpha-1 subunit 0.090 0.581
AIP AIP, XAP2: AH receptor-interacting protein 0.087 0.026
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.086 0.260
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.086 0.096
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.086 0.144
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.055
XPO1 XPO1, CRM1: Exportin-1 0.086 0.032
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.086 0.077
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.086 0.032
PPEF1 N/A 0.083 0.083
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.083
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.028
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.083 0.052
GNAT1 GNAT1, GNATR: Guanine nucleotide-binding protein G(t), alpha-1 subunit 0.081 0.644
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.080 0.144
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.077 0.109
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.077 0.127
WWC2 WW and C2 domain containing 2 0.077 0.055
AP2B1 AP2B1: Uncharacterized protein AP2B1 0.075 0.030
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.075 0.083
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.075 0.083
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.075 0.028
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.028
GNA13 GNA13: Guanine nucleotide-binding protein alpha-13 subunit 0.073 0.731
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.071 0.077
COPA COPA: Coatomer subunit alpha 0.071 0.127
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.071 0.026
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.071 0.077
RRAS RRAS: Ras-related protein R-Ras precursor 0.071 0.026
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.026
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.069 0.032
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.062
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.069 0.070
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.067 0.027
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.032
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.063 0.096
GNB2L1 Lung cancer oncogene 7 0.061 0.075
WDR1 N/A 0.061 0.091
HD HD, IT15: Huntingtin 0.060 0.032
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.060 0.032
GNAT2 GNAT2, GNATC: Guanine nucleotide-binding protein G(t), alpha-2 subunit 0.058 0.644
MEF2A N/A 0.057 0.027
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.056 0.0425
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.056 0.056
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.056 0.191
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.056 0.098
RAB11FIP5 RAB11FIP5, GAF1, KIAA0857, RIP11: Rab11 family-interacting protein 5 0.056 0.056
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.056 0.127
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.056 0.055
RASA3 RASA3: Ras GTPase-activating protein 3 0.056 0.062
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.054 0.0453
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.054 0.153
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.054 0.027
SEC31L1 N/A 0.054 0.075
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.054 0.048
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.054 0.070
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.054 0.0425
DYNC1I2 N/A 0.054 0.062
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.054 0.034
CASP8 CASP8, MCH5: Caspase-8 precursor 0.052 0.028
CASP14 CASP14: Caspase-14 precursor 0.052 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.052 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.052 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.052 0.028
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.052 0.026
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.052 0.096
MPG N/A 0.052 0.0425
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.051 0.037
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.050 0.056
SYTL4 Endocrine transmitter regulatory protein 0.049 0.049
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.049 0.049
STAM2 STAM2: Signal transducing adapter molecule 2 0.049 0.032
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.048 0.070
NIPBL N/A 0.047 0.028
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.028
CHP CHP: Calcium-binding protein p22 0.046 0.155
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.046 0.032
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.046 0.0425
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.046 0.032
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.046 0.191
EEF2 EEF2, EF2: Elongation factor 2 0.046 0.026
SHC1 SHC1, RP11-307C12.1-001, hCG_1997126: SHC 0.046 0.026
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.046 0.026
VCP VCP: Transitional endoplasmic reticulum ATPase 0.046 0.032
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.046 0.0425
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.046 0.191
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.046 0.0425
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.0425
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.046 0.032
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.046 0.032
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.046 0.0425
CFL1 CFL1, CFL: Cofilin-1 0.046 0.0425
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.032
NBN NBN, NBS, NBS1, P95: Nibrin 0.0453 0.027
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.0453 0.074
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.0453 0.027
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.044 0.055
GNAS GNAS, GNAS1, GSP: Guanine nucleotide-binding protein G(s) subunit alpha isoforms 0.044 0.543
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.043 0.0425
NRAS NRAS, HRAS1: GTPase NRas precursor 0.043 0.032
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.043 0.087
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.043 0.032
KIAA0690 N/A 0.043 0.052
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.043 0.052
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.043 0.077
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.0425 0.026
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.070
MVP MVP, LRP: Major vault protein 0.0425 0.260
DNM2 N/A 0.0425 0.052
SRPR SRPR: Uncharacterized protein SRPR 0.0425 0.0425
ABCF1 N/A 0.0425 0.026
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.0425 0.034
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.0425 0.070
SPTAN1 N/A 0.0425 0.056
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.0425 0.034
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.0425 0.080
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.041 0.541
COPB2 COPB2: Coatomer subunit beta' 0.041 0.057
GNAL GNAL: Guanine nucleotide-binding protein G(olf) subunit alpha 0.0407 0.357
STX7 STX7: Syntaxin-7 0.041 0.036
VDR VDR, NR1I1: Vitamin D3 receptor 0.041 0.027
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.041 0.157
WDR54 N/A 0.04 0.049
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.038 0.026
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.038 0.026
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.038 0.070
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.038 0.032
NCK2 NCK2: Cytoplasmic protein NCK2 0.038 0.026
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.032
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.038 0.032
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.038 0.032
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.038 0.032
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.038 0.052
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.038 0.087
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.038 0.052
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.038 0.049
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.038 0.049
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.038 0.026
RPS10 RPS10: 40S ribosomal protein S10 0.038 0.0425
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.038 0.0425
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.038 0.155
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.038 0.032
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.038 0.052
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.038 0.039
ACTG1 ACTB: Actin, cytoplasmic 1 0.038 0.087
PTPN11 N/A 0.038 0.026
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.038 0.127
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.038 0.087
DPYSL2 DPYSL2, CRMP2: Dihydropyrimidinase-related protein 2 0.038 0.026
CRK N/A 0.038 0.026
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.032
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.038 0.032
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.038 0.026
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.038 0.026
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.038 0.035
SAPS3 N/A 0.038 0.0425
QARS QARS: Glutaminyl-tRNA synthetase 0.038 0.0425
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.026
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.038 0.032
FLII FLII, FLIL: Protein flightless-1 homolog 0.038 0.132
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.038 0.210
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.038 0.070
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.038 0.026
GSK3B N/A 0.038 0.070
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.038 0.052
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.038 0.0425
VIM VIM: Vimentin 0.037 0.027
SH3BP3 0.037 0.091
GNA14 GNA14: Guanine nucleotide-binding protein alpha-14 subunit 0.036 0.322
ARL3 ARL3, ARFL3: ADP-ribosylation factor-like protein 3 0.036 0.174
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.036 0.049
GEMIN5 GEMIN5: Gem-associated protein 5 0.036 0.049
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.036 0.049
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.036 0.049
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.035 0.026
CORO1C CORO1C, CRNN4: Coronin-1C 0.033 0.091
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.033 0.0453
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.033 0.0453
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.033 0.036
API5 N/A 0.032 0.026
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.0425
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.032 0.052
IFI35 N/A 0.032 0.070
SNCB SNCB: Beta-synuclein 0.032 0.098
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.032 0.026
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.032 0.0425
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.0425
STK16 N/A 0.032 0.026
AHNAK AHNAK: AHNAK protein 0.032 0.087
SAT SAT1, SAT: Diamine acetyltransferase 1 0.032 0.087
FUBP1 N/A 0.032 0.032
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.032 0.039
NUP214 N/A 0.030 0.541
KLHDC4 N/A 0.029 0.032
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.029 0.032
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.029 0.052
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.029 0.032
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.029 0.055
CRKL CRKL: Crk-like protein 0.029 0.026
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.029 0.032
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.029 0.052
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.029 0.062
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.0425
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.029 0.052
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.029 0.123
STAT6 STAT6: Signal transducer and activator of transcription 6 0.029 0.430
DOK1 DOK1: Docking protein 1 0.029 0.087
CCT8 CCT8: Uncharacterized protein CCT8 0.029 0.026
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.029 0.070
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.029 0.026
PPARBP N/A 0.029 0.032
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.029 0.032
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.029 0.155
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.029 0.049
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.029 0.070
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.029 0.052
TPT1 TPT1: Translationally-controlled tumor protein 0.029 0.052
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.029 0.026
UBE4A N/A 0.029 0.052
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.029 0.032
JAK1 0.029 0.052
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.029 0.052
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.029 0.026
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.029 0.0425
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.029 0.070
TLN1 TLN1: Uncharacterized protein TLN1 0.029 0.070
MAD1L1 MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1 0.029 0.052
SH3BP5 N/A 0.029 0.032
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.029 0.026
FNBP1 N/A 0.029 0.0425
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.029 0.070
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 0.430
SEC24B SEC24B: Protein transport protein Sec24B 0.029 0.0425
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.0425
TBCE TBCE: Tubulin-specific chaperone E 0.029 0.048
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.029 0.052
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.029 0.026
KIAA1012 KIAA1012: Protein TRS85 homolog 0.029 0.070
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.029 0.052
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.029 0.052
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.029 0.032
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.029 0.032
MSN MSN: Moesin 0.029 0.087
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.032
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.029 0.087
DIAPH1 Diaphanous 1 0.029 0.070
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.029 0.032
HNRPK N/A 0.029 0.052
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.029 0.077
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.029 0.155
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.029 0.087
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.077
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.029 0.026
CSK CSK: Tyrosine-protein kinase CSK 0.029 0.052
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.052
LNK SH2B3, LNK: SH2B adapter protein 3 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.052
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
MAP2K5 N/A 0.028 0.028
MATK 0.028 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.028 0.028
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.083
NF2 NF2, SCH: Merlin 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
PHLDB2 N/A 0.028 0.028
CNN2 CNN2: Calponin-2 0.028 0.028
DNM3 DNM3: Uncharacterized protein DNM3 0.028 0.028
C9orf88 N/A 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
CACNB2 N/A 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.083
PKP4 PKP4: Plakophilin-4 0.028 0.052
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.083
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.028 0.028
CDC42 N/A 0.028 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.028 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.028 0.028
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
AMPH AMPH, AMPH1: Amphiphysin 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
AXIN1 0.028 0.028
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.028 0.165
PSCD2 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
MAPK15 N/A 0.028 0.028
NCF4 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
PTPN7 N/A 0.028 0.028
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.028 0.028
LNX1 N/A 0.028 0.028
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.027 0.037
CDC20 CDC20: Cell division cycle protein 20 homolog 0.027 0.032
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.027 0.032
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.026 0.144
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.098
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.026 0.055
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.026 0.155
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.026 0.052
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.026 0.052
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.026 0.260
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.026 0.144
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.026 0.026
IRS2 IRS2: Insulin receptor substrate 2 0.026 0.087
ZYX ZYX: Zyxin 0.026 0.087
LIMK2 LIMK2: LIM domain kinase 2 0.026 0.060
FLNA FLNA, FLN, FLN1: Filamin-A 0.026 0.070
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.026 0.144
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.026 0.026
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.026 0.0425
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.026 0.098
GAB2 N/A 0.026 0.087
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.026 0.026
WWC1 WWC1, KIAA0869: WW domain-containing protein 1 0.026 0.056
MARK2 N/A 0.026 0.070
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.026 0.0425
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.026 0.0425
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.026 0.210
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.026 0.430
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.026 0.210
LIMS1 N/A 0.026 0.087
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.026 0.026
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.026 0.032
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.0253 0.033
ADK ADK: Adenosine kinase 0.025 0.028
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.028
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.165
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.028
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.025 0.028
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.025 0.052
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.028
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.025 0.028
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.028
MYO18A 0.025 0.052
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.028
GIT2 N/A 0.025 0.165
PRKCB1 N/A 0.025 0.028
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.025 0.028
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.028
EPN2 N/A 0.025 0.028
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.083
RAC1 N/A 0.025 0.028
DBNL N/A 0.025 0.028
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.028
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.028
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.028
MAP2K3 N/A 0.025 0.028
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.052
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.083
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.028
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.028
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.025 0.028
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.028
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.028
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.083
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.025 0.028
GRK6 N/A 0.025 0.028
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.028
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.052
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.083
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.025 0.083
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.025 0.028
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.028
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.083
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.083
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.083
CFL2 CFL2: Cofilin-2 0.025 0.028
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.083
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.028
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.083
GSN GSN: Gelsolin precursor 0.025 0.028
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.028
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.028
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.028
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.028
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.025 0.028
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.025 0.083
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.028
CAMKK1 N/A 0.025 0.028
SVIL SVIL: Supervillin 0.025 0.028
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.028
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.025 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.028
BCR N/A 0.025 0.028
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.028
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.028
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.025 0.083
ELMO1 N/A 0.025 0.028
TSC2 TSC2, TSC4: Tuberin 0.025 0.028
RAD50 RAD50: DNA repair protein RAD50 0.025 0.028
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.028
CASP7 N/A 0.025 0.028
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.025 0.028
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.028
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.028
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.025 0.028
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.025 0.083
ARHGEF7 N/A 0.025 0.028
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.025 0.028
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.028
BCOR N/A 0.025 0.028
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.052
LMO6 LMO6: LIM domain only protein 6 0.025 0.028
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.028
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.025 0.028
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.052
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.028
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.028
CAMK2A N/A 0.025 0.028
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.028
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.028
STAT3 0.025 0.083
SCRIB N/A 0.025 0.028
SNX3 N/A 0.025 0.028
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.028
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.083
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.025 0.028
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.028
0.228
Total Score 1.9