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Evidence of Interaction Between INSR and HSP90AB1

The interaction score between INSR and HSP90AB1 is 6.52.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between INSR and HSP90AB1 = -0.00

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology N/A N/A
Domains Domains present in INSR and HSP90AB1:
Domains in INSRDomains in HSP90AB1
IPR000494 Epidermal growth-factor receptor (EGFR), L domain
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR006211 Furin-like cysteine rich region
IPR006212 Furin-like repeat
IPR008266 Tyrosine protein kinase, active site
IPR003961 Fibronectin, type III
IPR002011 Receptor tyrosine kinase, class II
IPR001404 Heat shock protein Hsp90
IPR003594 ATP-binding region, ATPase-like
IPR009079 Four-helical cytokine

The Chi square scores for co-occurrence of domains that are present in INSR and HSP90AB1 are listed below.

Domain 1Domain 2Chi Square
IPR003961 Fibronectin, type III IPR009079 Four-helical cytokine 42.8476
IPR000719 Protein kinase IPR001404 Heat shock protein Hsp90 4.2459
IPR008266 Tyrosine protein kinase, active site IPR009079 Four-helical cytokine 2.11982
IPR001245 Tyrosine protein kinase IPR001404 Heat shock protein Hsp90 1.02227
IPR008266 Tyrosine protein kinase, active site IPR003594 ATP-binding region, ATPase-like 0.773185
IPR000719 Protein kinase IPR003594 ATP-binding region, ATPase-like 0.689782
IPR001245 Tyrosine protein kinase IPR009079 Four-helical cytokine 0.23317
IPR001245 Tyrosine protein kinase IPR003594 ATP-binding region, ATPase-like 0.113166
IPR008266 Tyrosine protein kinase, active site IPR001404 Heat shock protein Hsp90 0.0171111
IPR000719 Protein kinase IPR009079 Four-helical cytokine 0.00559597

The background colour of the table refers to:

  • Blue Domain is only present in INSR
  • Yellow Domain is only present in HSP90AB1
  • Green Domain is present in both INSR and HSP90AB1

 0.109
Post-translational Modifications

Protein: INSR

PTMResidueReference
Dephosphorylation 999 PubMed, HPRD
Dephosphorylation 1185 PubMed, HPRD
Dephosphorylation 1189 PubMed, HPRD
Dephosphorylation 1190 PubMed, HPRD
Glycosylation 43 PubMed, HPRD
Glycosylation 52 PubMed, HPRD
Glycosylation 105 PubMed, HPRD
Glycosylation 138 PubMed, HPRD
Glycosylation 424 PubMed, HPRD
Glycosylation 445 PubMed, HPRD
Glycosylation 769 PubMed, HPRD
Glycosylation 782 PubMed, HPRD
Glycosylation 920 PubMed, HPRD
Glycosylation 933 PubMed, HPRD
N-linked 541 PubMed, HPRD
Phosphorylation 992 PubMed, HPRD
Phosphorylation 999 PubMed, HPRD
Phosphorylation 1062 PubMed, HPRD
Phosphorylation 1064 PubMed, HPRD
Phosphorylation 1185 PubMed, HPRD
Phosphorylation 1189 PubMed, HPRD
Phosphorylation 1190 PubMed, HPRD
Phosphorylation 1314 PubMed, HPRD
Phosphorylation 1332 PubMed, HPRD
Phosphorylation 1333 PubMed, HPRD
Phosphorylation 1348 PubMed, HPRD
Phosphorylation 1354 PubMed, HPRD
Phosphorylation 1355 PubMed, HPRD
Phosphorylation 1361 PubMed, HPRD
Phosphorylation 1362 PubMed, HPRD
Phosphorylation 1375 PubMed, HPRD
Phosphotyrosine 992 PubMed, HPRD
Phosphotyrosine 999 PubMed, HPRD
Phosphotyrosine 1011 PubMed, HPRD
Phosphotyrosine 1185 PubMed, HPRD
Phosphotyrosine 1189 PubMed, HPRD
Phosphotyrosine 1190 PubMed, HPRD
Phosphotyrosine 1355 PubMed, HPRD
Phosphotyrosine 1361 PubMed, HPRD

Protein: HSP90AB1

PTMResidueReference
Phosphorylation 255 PubMed, HPRD
Phosphorylation 261 PubMed, HPRD
Phosphoserine 225 HPRD
Phosphoserine 254 HPRD
Phosphoserine 260 HPRD
Phosphotyrosine 483 HPRD
Localisation

Protein: INSR

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD

Protein: HSP90AB1

LocalisationReference
Nucleus HPRD
Nucleolus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between INSR and HSP90AB1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between INSR andHSP90AB1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , INSR has 1177 interactors and HSP90AB1 has 1223 interactors of which there are 464 common interactors.

Common InteractorName of Common InteractorScore for INSR-Interactor (?)Score for HSP90AB1-Interactor (?)
JAK2 JAK2: Tyrosine-protein kinase JAK2 277.00 0.077
CRKL CRKL: Crk-like protein 277.00 0.087
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 277.00 0.127
STAT5B STAT5B: Signal transducer and activator of transcription 5B 173.00 0.075
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 56.70 0.0446
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 46.90 0.083
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 15.80 0.056
YWHAB YWHAB: 14-3-3 protein beta/alpha 12.50 0.0425
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 0.083
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.028
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.028
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 0.083
BMX N/A 0.902 0.055
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.902 0.786
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.878 0.083
STAT3 0.878 0.028
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.878 0.083
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.878 0.028
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.878 0.028
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.731 0.026
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 0.096
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.655 0.055
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.644 0.070
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.644 0.127
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.644 0.055
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.644 0.062
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.586 0.052
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.581 0.077
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.581 0.096
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.577 0.210
APS SH2B2, APS: SH2B adapter protein 2 0.577 0.026
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.577 0.127
HCK N/A 0.577 0.055
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.577 0.155
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.577 0.077
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.577 0.062
LYN LYN: Tyrosine-protein kinase Lyn 0.577 0.077
RIN1 RIN1: Ras and Rab interactor 1 0.577 0.032
STAT6 STAT6: Signal transducer and activator of transcription 6 0.577 0.096
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.577 0.055
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.577 0.062
SYK SYK: Tyrosine-protein kinase SYK 0.577 0.096
CSK CSK: Tyrosine-protein kinase CSK 0.520 0.155
JAK1 0.520 0.077
NCK2 NCK2: Cytoplasmic protein NCK2 0.520 0.032
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.520 0.062
VAV1 VAV1, VAV: Proto-oncogene vav 0.520 0.032
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.320 0.0453
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.307 0.072
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 0.037
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.065
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.191 0.065
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.191 0.0727
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.171 0.029
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.171 0.029
LDLR LDLR: Low-density lipoprotein receptor precursor 0.171 0.046
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.171 0.100
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.04
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
FN1 N/A 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.049
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.049
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.049
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.049
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.049
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.152 0.026
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.152 0.033
PRLR PRLR: Prolactin receptor precursor 0.152 0.0727
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.109
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.049
BSG N/A 0.148 0.049
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.049
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.109
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.109
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.148 0.049
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.109
ATRN N/A 0.148 0.049
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.136 0.033
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.136 0.037
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.136 0.029
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.136 0.081
MEP1A MEP1A: Meprin A subunit alpha precursor 0.136 0.0263
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.126 0.046
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.123 0.081
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.123 0.033
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.123 0.126
F3 F3: Tissue factor precursor 0.123 0.081
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.100
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.123 0.0263
GHR GHR: Growth hormone receptor precursor 0.123 0.166
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.123 0.072
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.032
ITGB4 N/A 0.123 0.081
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.065
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.123 0.065
EPOR EPOR: Erythropoietin receptor precursor 0.123 0.081
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.114 0.030
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.113 0.127
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.110 0.065
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.110 0.072
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.110 0.029
KIT KIT: Mast/stem cell growth factor receptor precursor 0.110 0.075
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.110 0.057
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.110 0.0727
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.110 0.072
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.110 0.032
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.110 0.081
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
PSCD2 N/A 0.109 0.028
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.083
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.083
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.028
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.028
CNN2 CNN2: Calponin-2 0.109 0.028
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.028
MAPK15 N/A 0.109 0.083
NF2 NF2, SCH: Merlin 0.109 0.028
PPEF1 N/A 0.109 0.083
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.083
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.109 0.0453
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.109 0.037
AREG AREG, SDGF: Amphiregulin precursor 0.109 0.037
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.109 0.081
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.109 0.032
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.109 0.0263
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.100
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.109 0.0453
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.081
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.109 0.027
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.052
SELE SELE, ELAM1: E-selectin precursor 0.109 0.032
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.100 0.025
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.098 0.027
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.037
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.037
CRLF3 N/A 0.098 0.126
IL9R IL9R: Interleukin-9 receptor precursor 0.098 0.081
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.098 0.081
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.075
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.098 0.030
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.098 0.075
SORL1 SORL1: Sortilin-related receptor precursor 0.098 0.126
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.098 0.083
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.083
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.083
ELMO1 N/A 0.098 0.028
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.083
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 0.083
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.165
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.083
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.098 0.083
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.098 0.083
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.028
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.034
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.028
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.028
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.098 0.083
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.083
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.028
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.028
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.083
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.098 0.083
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.083
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.028
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.0688
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.028
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.028
SNX3 N/A 0.098 0.028
ARHGEF7 N/A 0.098 0.028
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.098 0.028
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.083
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.097 0.081
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.097 0.065
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.065
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.097 0.081
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.097 0.0263
TNC TNC, HXB: Tenascin precursor 0.097 0.072
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.274
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.097 0.032
DCC DCC: Netrin receptor DCC precursor 0.097 0.072
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.097 0.032
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.097 0.056
GP1BA N/A 0.096 0.072
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.0333
REG1B REG1A, PSPS, REG: Lithostathine 1 alpha precursor 0.091 0.025
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.090 0.052
PLD1 PLD1: Phospholipase D1 0.090 0.052
VIL2 N/A 0.090 0.0425
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.088 0.029
PTPRZ1 N/A 0.088 0.081
NEO1 NEO1, NGN: Neogenin precursor 0.088 0.065
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.088 0.081
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.088 0.081
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.088 0.065
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.086 0.034
OPTC OPTC, OPT: Opticin precursor 0.083 0.049
EDA N/A 0.083 0.049
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.083 0.109
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.083 0.049
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.083 0.109
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.081 0.055
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.081 0.096
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.051
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.081 0.026
S100A3 S100A3, S100E: Protein S100-A3 0.081 0.055
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.081 0.026
GAB2 N/A 0.081 0.026
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.081 0.032
PLD2 PLD2: Phospholipase D2 0.073 0.026
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.073 0.096
TLN1 TLN1: Uncharacterized protein TLN1 0.073 0.032
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.073 0.032
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.073 0.025
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.073 0.049
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.073 0.045
RDX RDX: Radixin 0.073 0.0425
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.026
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.072 0.062
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.077
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.072 0.077
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.072 0.032
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.072 0.051
S100B S100B: Protein S100-B 0.072 0.055
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.072 0.055
S100A7 S100A7, PSOR1: Protein S100-A7 0.072 0.049
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.026
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.072 0.062
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.055
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.096
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.065 0.155
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.032
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.065 0.127
COL5A1 N/A 0.065 0.025
ROCK1 ROCK1: Rho-associated protein kinase 1 0.065 0.127
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.065 0.127
SPTAN1 N/A 0.065 0.062
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.065 0.062
STK16 N/A 0.065 0.127
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.0425
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.096
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.064 0.026
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.064 0.096
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.064 0.0425
PSCD4 PSCD4, CYT4: Cytohesin-4 0.064 0.026
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.064 0.055
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.064 0.055
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.064 0.0425
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.064 0.251
CD2AP CD2AP: CD2-associated protein 0.064 0.087
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.064 0.077
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.064 0.032
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.064 0.055
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.064 0.096
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.064 0.055
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.064 0.045
FNBP1 N/A 0.064 0.070
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.064 0.0425
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.064 0.062
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.064 0.0513
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.064 0.077
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.064 0.155
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.064 0.052
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.064 0.032
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.064 0.210
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.064 0.055
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.064 0.056
RPS6KB1 N/A 0.064 0.155
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.064 0.055
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.025
LCP1 LCP1, PLS2: Plastin-2 0.064 0.155
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.064 0.063
HSP90AA1 Hsp89-alpha-delta-N 0.064 0.260
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.064 0.052
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.064 0.052
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.064 0.062
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.064 0.127
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.064 0.062
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.064 0.077
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.064 0.155
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.064 0.026
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.064 0.430
CHP CHP: Calcium-binding protein p22 0.064 0.077
MYL3 MYL3: Myosin light polypeptide 3 0.064 0.055
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.064 0.096
TTN N/A 0.064 0.049
TP73 TP73, P73: Tumor protein p73 0.063 0.037
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.062 0.032
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.062 0.032
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.049
CETN1 CETN1, CEN1, CETN: Centrin-1 0.062 0.049
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.062 0.049
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.058 0.127
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.058 0.026
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.058 0.155
DOK1 DOK1: Docking protein 1 0.058 0.032
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.058 0.127
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.058 0.032
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.058 0.070
CXorf9 N/A 0.058 0.127
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.058 0.032
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.058 0.026
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.058 0.127
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.058 0.127
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.058 0.032
ACTN1 ACTN1: Alpha-actinin-1 0.058 0.062
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.058 0.0425
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.058 0.077
STMN1 STMN1, LAP18, OP18: Stathmin 0.058 0.070
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.058 0.096
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.058 0.026
MSN MSN: Moesin 0.058 0.032
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.058 0.096
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.058 0.077
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.058 0.055
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.056 0.072
TLR4 TLR4: Toll-like receptor 4 precursor 0.056 0.065
GP9 GP9: Platelet glycoprotein IX precursor 0.055 0.072
FADD FADD, MORT1: Protein FADD 0.055 0.124
ASGR2 ASGR2: Asialoglycoprotein receptor 2 0.055 0.032
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.054 0.096
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.053 0.0782
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.052 0.049
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
NCAM1 N/A 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
COL4A1 N/A 0.051 0.045
CD69 CD69: Early activation antigen CD69 0.049 0.0453
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.049 0.100
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.027
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.049 0.081
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.049 0.028
DCN DCN: Decorin precursor 0.049 0.034
YWHAG YWHAG: 14-3-3 protein gamma 0.049 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.083
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.083
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.083
MAP2K5 N/A 0.049 0.083
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.049 0.027
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.049 0.030
TPBG TPBG, 5T4: Trophoblast glycoprotein precursor 0.049 0.100
ASGR1 ASGR1: Asialoglycoprotein receptor 1 0.049 0.029
ITGAV ITGAV, MSK8, VNRA: Integrin alpha-V precursor 0.049 0.0453
GP5 GP5: Platelet glycoprotein V precursor 0.049 0.065
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.051
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.051
FKBP9 FKBP9, FKBP60, FKBP63: FK506-binding protein 9 precursor 0.046 0.025
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.045 0.0446
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.062
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.083
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.028
TSC2 TSC2, TSC4: Tuberin 0.044 0.028
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.044 0.034
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.028
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.083
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.028
RYR2 RYR2: Ryanodine receptor 2 0.041 0.025
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.041 0.074
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.041 0.026
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.041 0.049
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.041 0.036
FKBP10 FKBP10, FKBP65, PSEC0056: FK506-binding protein 10 precursor 0.041 0.031
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.0446
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.028
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.039 0.032
COL1A1 COL1A1: Collagen alpha-1(I) chain precursor 0.037 0.025
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.037 0.032
COL17A1 COL17A1, BP180, BPAG2: Collagen alpha-1(XVII) chain 0.037 0.025
GAS2 GAS2: Growth arrest-specific protein 2 0.037 0.0425
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.037 0.0446
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.037 0.036
SOS1 SOS1: Son of sevenless homolog 1 0.037 0.075
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.037 0.036
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.036 0.083
GSN GSN: Gelsolin precursor 0.036 0.028
SVIL SVIL: Supervillin 0.036 0.028
COTL1 COTL1, CLP: Coactosin-like protein 0.036 0.028
CFL2 CFL2: Cofilin-2 0.036 0.028
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.037
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.032
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.033 0.032
IGFALS IGFALS, ALS: Insulin-like growth factor-binding protein complex acid labile chai 0.033 0.045
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.033 0.026
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.033 0.308
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.033 0.032
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.033 0.062
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.032 1.81
COL16A1 COL16A1: Collagen alpha-1(XVI) chain precursor 0.032 0.031
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.032 0.052
FUBP1 N/A 0.032 0.260
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.032 0.191
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.210
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.032 0.062
COL5A2 N/A 0.032 0.025
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.077
TSHR N/A 0.0308 0.032
TNN TNN: Tenascin-N precursor 0.030 0.0338
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.029 0.155
YWHAQ YWHAQ: 14-3-3 protein theta 0.029 0.087
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.029 0.096
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.029 0.026
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.029 0.026
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.029 0.260
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.029 0.308
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.029 0.055
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.049
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.029 0.144
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.155
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.087
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.077
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.029 0.144
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.029 0.070
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.062
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.029 0.087
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.0425
CTPS CTPS: CTP synthase 1 0.029 0.144
YWHAE YWHAE: 14-3-3 protein epsilon 0.029 0.070
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.144
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.029 0.0425
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.029 0.308
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.029 0.0425
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.028 0.027
WNT2B WNT2B, WNT13: Protein Wnt-2b precursor 0.027 0.041
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.027 0.052
DBN1 DBN1, D0S117E: Drebrin 0.027 0.0425
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.096
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.026 0.070
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.026 0.026
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.026 0.0425
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.026 0.144
ATM ATM: Serine-protein kinase ATM 0.026 0.096
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.026 0.036
FLII FLII, FLIL: Protein flightless-1 homolog 0.026 0.096
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.026 0.430
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.127
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.026 0.127
MDN1 MDN1, KIAA0301: Midasin 0.026 0.087
WASPIP N/A 0.026 0.0425
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.026 0.070
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.026 0.416
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.025 0.032
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.025 0.083
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.049
0.228
Total Score 6.52