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Evidence of Interaction Between AGTR1 and TEC

The interaction score between AGTR1 and TEC is 10.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between AGTR1 and TEC = 0.11

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.30E-3
Orthology N/A N/A
Domains Domains present in AGTR1 and TEC:
Domains in AGTR1Domains in TEC
IPR000276 Rhodopsin-like GPCR superfamily
IPR001186 B1 bradykinin receptor
IPR000248 Angiotensin II receptor
IPR000190 AT1 angiotensin II receptor
IPR001277 C-X-C chemokine receptor, type 4
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR001849 Pleckstrin-like
IPR001452 SH3
IPR000980 SH2 motif
IPR001562 Tec/Btk domain
IPR011993 PH_type.

The Chi square scores for co-occurrence of domains that are present in AGTR1 and TEC are listed below.

Domain 1Domain 2Chi Square
IPR000276 Rhodopsin-like GPCR superfamily IPR000719 Protein kinase 23.5469
IPR000276 Rhodopsin-like GPCR superfamily IPR001452 SH3 20.5036
IPR000276 Rhodopsin-like GPCR superfamily IPR001245 Tyrosine protein kinase 15.1425
IPR000276 Rhodopsin-like GPCR superfamily IPR011009 Protein kinase-like 8.97709
IPR000276 Rhodopsin-like GPCR superfamily IPR000980 SH2 motif 8.84423
IPR000276 Rhodopsin-like GPCR superfamily IPR008266 Tyrosine protein kinase, active site 8.24439
IPR000276 Rhodopsin-like GPCR superfamily IPR001849 Pleckstrin-like 6.22546
IPR000276 Rhodopsin-like GPCR superfamily IPR011993 PH_type. 3.78429
IPR000190 AT1 angiotensin II receptor IPR011009 Protein kinase-like 0.759514
IPR001277 C-X-C chemokine receptor, type 4 IPR000980 SH2 motif 0.660404
IPR001277 C-X-C chemokine receptor, type 4 IPR000719 Protein kinase 0.348153
IPR001277 C-X-C chemokine receptor, type 4 IPR011009 Protein kinase-like 0.0729026
IPR000190 AT1 angiotensin II receptor IPR000719 Protein kinase 0.0620095
IPR001277 C-X-C chemokine receptor, type 4 IPR008266 Tyrosine protein kinase, active site 0.00738268
IPR001277 C-X-C chemokine receptor, type 4 IPR001245 Tyrosine protein kinase 0.00425456

The background colour of the table refers to:

  • Blue Domain is only present in AGTR1
  • Yellow Domain is only present in TEC
  • Green Domain is present in both AGTR1 and TEC

 0.049
Post-translational Modifications

Protein: AGTR1

PTMResidueReference
Phosphorylation 302 PubMed, HPRD
Phosphorylation 319 PubMed, HPRD

Protein: TEC

PTMResidueReference
Phosphorylation 206 PubMed, HPRD
Localisation

Protein: AGTR1

LocalisationReference
Plasma membrane HPRD

Protein: TEC

LocalisationReference
Cytoplasm HPRD
Transitive Score

The common interactors between AGTR1 and TEC that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between AGTR1 andTEC. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , AGTR1 has 740 interactors and TEC has 1520 interactors of which there are 518 common interactors.

Common InteractorName of Common InteractorScore for AGTR1-Interactor (?)Score for TEC-Interactor (?)
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 1.30 0.044
GNA13 GNA13: Guanine nucleotide-binding protein alpha-13 subunit 1.20 0.041
GNAT1 GNAT1, GNATR: Guanine nucleotide-binding protein G(t), alpha-1 subunit 1.20 0.051
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 1.20 13.90
GNAI1 GNAI1: Guanine nucleotide-binding protein G(i), alpha-1 subunit 0.975 13.90
GNAT2 GNAT2, GNATC: Guanine nucleotide-binding protein G(t), alpha-2 subunit 0.975 0.033
GNA14 GNA14: Guanine nucleotide-binding protein alpha-14 subunit 0.970 3.65
GNA12 GNA12: Guanine nucleotide-binding protein alpha-12 subunit 0.859 0.033
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.775 0.032
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 0.775 0.029
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.775 13.90
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 0.775 0.033
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 2 0.775 0.032
GNAI2 Galphai2 protein 0.775 0.029
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.340 0.045
DAB2 DAB2, DOC2: Disabled homolog 2 0.253 0.097
AMBP AMBP, HCP, ITIL: AMBP protein precursor [Contains: Alpha-1-microglobulin 0.166 0.039
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.166 0.109
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.157 0.045
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.155 0.073
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.155 0.902
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.155 0.808
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.153 0.045
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.127 0.577
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.127 0.655
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.127 277.00
INSR INSR: Insulin receptor precursor 0.127 0.577
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.126 108.00
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.126 0.094
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.109 0.165
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.109 0.148
AXIN1 0.109 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.165
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.109 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.109 0.148
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.109 0.028
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.109 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.109 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.109 0.165
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.109 0.136
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.100 1.98
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.096 0.808
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.096 0.057
F10 F10: Coagulation factor X precursor 0.096 0.051
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.096 1.01
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.096 0.520
HPN HPN, TMPRSS1: Serine protease hepsin 0.096 0.051
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.096 0.731
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.096 0.577
MET MET: Hepatocyte growth factor receptor precursor 0.096 0.902
CFI CFI, IF: Complement factor I precursor 0.091 0.031
C2 C2: Complement C2 precursor 0.091 0.039
F9 F9: Coagulation factor IX precursor 0.091 0.046
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.091 0.098
CFB CFB, BF, BFD: Complement factor B precursor 0.091 0.031
SDC1 SDC1, SDC: Syndecan-1 precursor 0.087 0.037
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.087 0.081
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.083 0.878
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.148
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.083 0.878
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 46.90
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.083 0.980
DRD2 DRD2: D(2) dopamine receptor 0.083 0.049
TMPRSS9 N/A 0.083 0.049
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.083 0.980
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.083 0.980
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.083 0.878
TBXA2R TBXA2R: Thromboxane A2 receptor 0.083 0.04
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.083 0.878
FABP1 FABP1, FABPL: Fatty acid-binding protein, liver 0.082 0.051
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.081 0.110
TSHB TSHB: Thyrotropin subunit beta precursor 0.081 0.051
FSHB FSHB: Follitropin subunit beta precursor 0.081 0.051
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.081 0.088
LHB LHB: Lutropin subunit beta precursor 0.081 0.045
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.081 0.191
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.077 0.655
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.077 0.090
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.077 1.01
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.077 0.808
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.077 0.808
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.077 0.520
RHO RHO, OPN2: Rhodopsin 0.077 0.057
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.075 0.109
C1R C1R: Complement C1r subcomponent precursor 0.075 0.025
CGA CGA: Glycoprotein hormones alpha chain precursor 0.075 0.045
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.075 0.039
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.0727 0.088
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.0727 46.80
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.072 0.088
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 0.046
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.072 0.110
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.072 0.136
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.072 0.110
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.072 0.110
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.072 0.123
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.072 0.110
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.072 46.80
JAK1 0.065 0.770
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.088
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.065 370.00
PMP2 PMP2: Myelin P2 protein 0.065 0.088
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.065 0.110
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.065 0.097
RPS6KB1 N/A 0.065 0.110
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.065 0.097
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 42.20
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.065 0.032
ROCK1 ROCK1: Rho-associated protein kinase 1 0.065 0.152
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.065 0.874
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.065 0.110
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.065 0.136
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.088
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.065 0.110
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.062 0.029
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.062 0.110
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.062 1.13
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.073
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.062 0.072
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.062 0.033
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.062 0.073
KCNJ1 KCNJ1, ROMK1: ATP-sensitive inward rectifier potassium channel 1 0.062 0.030
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.062 0.808
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.061 0.045
VIL2 N/A 0.057 0.136
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.057 0.110
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.057 0.110
F12 F12: Coagulation factor XII precursor 0.057 0.039
PROC PROC: Vitamin K-dependent protein C precursor 0.057 0.035
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.057 127.00
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.057 0.088
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.057 0.225
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.055 0.577
CCR5 CCR5: CCR5 receptor (Fragment) 0.055 0.081
KCNJ12 KCNJ12, IRK2, KCNJN1: ATP-sensitive inward rectifier potassium channel 12 0.055 0.033
DRD1 DRD1: D(1A) dopamine receptor 0.055 0.029
IL8RB IL8RB, CXCR2: High affinity interleukin-8 receptor B 0.055 0.037
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.055 0.033
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.055 0.731
KIT KIT: Mast/stem cell growth factor receptor precursor 0.055 0.520
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.055 0.126
TSHR N/A 0.055 0.029
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.052 0.044
CDH5 CDH5: Cadherin-5 precursor 0.052 0.032
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.052 0.073
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
EPB41 EPB41, E41P: Protein 4.1 0.051 0.046
PRKCD PRKCD: Protein kinase C delta type 0.051 0.051
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.049 0.577
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.049 0.100
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.049 0.110
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.049 0.123
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.049 0.110
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.049 0.037
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.049 0.577
ARHGEF7 N/A 0.049 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.049 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.049 0.148
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.049 1.30
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.049 563.00
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.165
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.049 1.17
MAPKAPK5 N/A 0.049 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.165
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.049 1.30
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.049 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.165
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.049 1.17
F7 F7: Coagulation factor VII precursor 0.049 0.030
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.049 1.30
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.165
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.049 1.17
MAP2K5 N/A 0.049 0.165
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.049 1.17
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.049 0.148
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.049 1.30
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.148
DNM3 DNM3: Uncharacterized protein DNM3 0.049 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.049 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.049 0.148
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.049 0.165
NF2 NF2, SCH: Merlin 0.049 0.165
ELMO1 N/A 0.049 0.148
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.049 0.484
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.165
MAPK15 N/A 0.049 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.165
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.148
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.049 1.30
PLAT PLAT: Tissue-type plasminogen activator precursor 0.049 0.030
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.148
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.165
STAT3 0.049 1.30
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.049 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.049 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.148
PSCD2 N/A 0.049 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.165
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.046 0.097
WEE1 WEE1: Wee1-like protein kinase 0.0453 0.136
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.123
CDK6 CDK6: Cell division protein kinase 6 0.0453 0.110
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.0453 1.07
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.0453 1.50
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.0453 0.097
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.0453 0.225
NOS1 NOS1: Nitric-oxide synthase, brain 0.0453 0.071
RDX RDX: Radixin 0.0453 0.097
IRS1 IRS1: Insulin receptor substrate 1 0.0453 0.152
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.0453 0.225
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.136
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.0453 0.136
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.0453 0.171
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.0453 0.098
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.044 0.056
GRK7 GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor 0.044 0.056
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.044 0.088
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0425 0.032
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.0425 0.057
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.0425 0.064
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.0425 0.029
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.0425 0.032
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.04 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.04 0.165
PPEF1 N/A 0.04 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.04 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.04 0.165
ACTN4 ACTN4: Alpha-actinin-4 0.04 0.148
S100A16 S100A16, AAG13: Protein S100-A16 0.04 0.165
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.04 0.148
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.04 0.148
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.039 0.041
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.039 0.041
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.037 0.097
SPARC SPARC, ON: SPARC precursor 0.037 0.041
CHP CHP: Calcium-binding protein p22 0.037 0.097
IRS2 IRS2: Insulin receptor substrate 2 0.037 0.098
PLD1 PLD1: Phospholipase D1 0.037 0.171
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.037 0.110
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.037 0.191
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.136
BMX N/A 0.037 1.50
TLN1 TLN1: Uncharacterized protein TLN1 0.037 0.136
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.037 0.110
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.037 0.098
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.037 0.775
CDK2 CDK2: Cell division protein kinase 2 0.037 0.110
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.037 0.136
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.037 0.109
PLD2 PLD2: Phospholipase D2 0.037 0.171
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.037 0.049
CDKL5 N/A 0.037 0.123
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.037 0.874
GAB1 GAB1: GRB2-associated-binding protein 1 0.037 0.191
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.037 0.097
MYO3A MYO3A: Myosin IIIA 0.037 0.171
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.037 1.50
DAPK2 DAPK2: Death-associated protein kinase 2 0.037 0.152
ALK ALK: ALK tyrosine kinase receptor precursor 0.037 0.445
F5 F5: Coagulation factor V precursor 0.036 0.063
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.036 0.051
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.034 0.029
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.034 0.038
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.034 0.034
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.034 422.00
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.034 0.098
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.098
CAV1 CAV1, CAV: Caveolin-1 0.033 0.030
PSD TYL: TYL protein 0.033 0.088
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.033 0.097
CDK5 CDK5: Cell division protein kinase 5 0.033 0.097
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.033 0.097
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.033 0.097
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.033 0.097
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.033 0.088
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.033 0.097
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.033 0.088
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.033 0.097
STK16 N/A 0.032 0.152
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.152
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.032 0.136
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.136
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.032 0.975
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.032 0.136
VASP VASP: Vasodilator-stimulated phosphoprotein 0.032 0.123
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.032 0.110
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.032 0.110
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.032 0.097
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.032 0.171
TLN2 TLN2: Uncharacterized protein TLN2 0.032 0.097
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.032 0.136
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.032 0.152
CRKL CRKL: Crk-like protein 0.032 1.07
PRKAA1 N/A 0.032 0.109
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.032 0.110
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.032 0.859
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.032 0.110
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.032 0.191
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.032 0.097
NCK2 NCK2: Cytoplasmic protein NCK2 0.032 0.874
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.032 0.123
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.032 0.109
NDP NDP: Norrin precursor 0.032 0.051
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.032 0.694
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.032 1.20
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.032 0.110
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.136
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.032 0.136
DAB1 DAB1: Disabled homolog 1 0.032 0.110
STAT6 STAT6: Signal transducer and activator of transcription 6 0.032 420.00
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.032 0.975
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.032 0.123
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.032 0.097
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.032 0.097
MUC2 MUC2, SMUC: Mucin-2 precursor 0.032 0.039
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.032 0.152
RASA3 RASA3: Ras GTPase-activating protein 3 0.032 0.110
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.032 0.251
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.032 0.110
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.032 0.975
APS SH2B2, APS: SH2B adapter protein 2 0.032 1.78
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.032 0.874
DOK1 DOK1: Docking protein 1 0.032 0.136
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.032 0.046
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.123
FLNA FLNA, FLN, FLN1: Filamin-A 0.032 0.049
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.032 0.770
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.032 0.045
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.032 0.171
CDK4 CDK4: Cell division protein kinase 4 0.032 0.136
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.123
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.032 0.081
GHR GHR: Growth hormone receptor precursor 0.032 0.100
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.032 0.126
GP1BA N/A 0.032 0.057
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.032 0.065
ANXA9 ANXA9, ANX31: Annexin A9 0.032 0.037
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.032 0.0453
LDLR LDLR: Low-density lipoprotein receptor precursor 0.032 0.033
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.032 0.081
PRLR PRLR: Prolactin receptor precursor 0.032 0.126
AVPR1A AVPR1A, AVPR1: Vasopressin V1a receptor 0.031 0.046
AVPR2 AVPR2, ADHR, DIR, DIR3, V2R: Vasopressin V2 receptor 0.031 0.046
AVPR1B AVPR1B, AVPR3, VPR3: Vasopressin V1b receptor 0.031 0.031
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.031 0.033
S100A3 S100A3, S100E: Protein S100-A3 0.030 0.123
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.030 0.191
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.030 0.225
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.030 0.109
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.029 0.110
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.029 0.770
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.029 0.097
CSK CSK: Tyrosine-protein kinase CSK 0.029 1.07
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.097
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.029 0.975
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.110
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.029 0.097
MSN MSN: Moesin 0.029 0.097
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.029 0.770
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.029 0.110
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.029 0.097
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.029 0.110
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.097
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.136
CDK7 CDK7, MO15: Cell division protein kinase 7 0.029 0.110
HCK N/A 0.029 0.770
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.171
DYRK3 N/A 0.029 0.097
VAV1 VAV1, VAV: Proto-oncogene vav 0.029 0.874
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.029 0.191
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.029 0.097
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.029 0.123
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.029 0.123
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.029 0.859
STK10 STK10: Uncharacterized protein STK10 0.029 0.097
RIN1 RIN1: Ras and Rab interactor 1 0.029 0.874
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.029 0.109
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.029 0.097
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.097
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.029 0.152
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.029 0.123
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.029 370.00
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.029 0.097
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.097
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.029 0.874
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.097
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.029 0.110
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.029 0.109
SYK SYK: Tyrosine-protein kinase SYK 0.029 0.874
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.029 0.110
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.029 1.20
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.029 0.097
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.029 0.770
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.029 0.123
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.029 0.152
PSCD4 PSCD4, CYT4: Cytohesin-4 0.029 0.097
GAB2 N/A 0.029 0.098
ATM ATM: Serine-protein kinase ATM 0.029 0.110
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.029 0.097
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.029 0.097
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.029 0.097
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.029 0.975
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.029 0.110
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.029 1.07
LYN LYN: Tyrosine-protein kinase Lyn 0.029 1.20
MCF2 MCF2, DBL: Proto-oncogene DBL 0.029 0.191
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.028 0.109
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.028 0.098
EDA N/A 0.028 0.049
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.028 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.109
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.049
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.028 0.109
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.098
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.028 0.109
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.028 0.049
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.028 0.109
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.028 0.049
JAG2 JAG2: Jagged-2 precursor 0.028 0.044
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.028 0.109
CNTN4 CNTN4: Contactin-4 precursor 0.028 0.098
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.028 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.028 0.109
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.028 0.044
ATRN N/A 0.028 0.098
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.028 0.049
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.044
AQP4 AQP4: Aquaporin-4 0.028 0.036
KIR3DL1 N/A 0.028 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.028 0.109
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.098
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
FN1 N/A 0.028 0.109
CDH6 CDH6: Cadherin-6 precursor 0.028 0.049
NULL A1BG: Alpha-1B-glycoprotein precursor 0.028 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.028 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.028 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.028 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.028 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.109
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.028 0.049
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.028 0.098
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.028 0.098
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.028 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.109
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.028 0.049
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.028 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.098
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.028 0.049
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.028 0.04
PCDHA2 PCDHA2: Protocadherin alpha 2 precursor 0.028 0.049
CNTN1 CNTN1: Contactin-1 precursor 0.028 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.028 0.098
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.049
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.028 0.098
OPTC OPTC, OPT: Opticin precursor 0.028 0.049
DLK1 DLK1, DLK: Delta-like protein precursor 0.028 0.049
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.028 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.028 0.109
BSG N/A 0.028 0.098
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.028 0.109
C8B C8B: Complement component C8 beta chain precursor 0.027 0.035
ANGPTL3 ANGPTL3, ANGPT5, UNQ153/PRO179: Angiopoietin-related protein 3 precursor 0.027 0.031
FGB FGB: Fibrinogen beta chain precursor [Contains: Fibrinopeptide B] 0.027 0.028
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.0263 0.123
MYL3 MYL3: Myosin light polypeptide 3 0.0263 0.110
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.0263 0.109
ACTN1 ACTN1: Alpha-actinin-1 0.0263 0.097
S100A7 S100A7, PSOR1: Protein S100-A7 0.0263 0.123
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.0263 0.110
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.0263 0.051
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.0263 0.097
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.0263 0.097
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.026 0.109
PVR PVR, PVS: Poliovirus receptor precursor 0.026 0.126
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.026 0.037
GLRA1 N/A 0.026 0.067
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.026 0.058
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.026 0.148
TNC TNC, HXB: Tenascin precursor 0.026 0.058
DSC2 DSC2, DSC3: Desmocollin-2 precursor 0.026 0.0453
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.026 0.072
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.026 0.274
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.026 0.166
ITGB4 N/A 0.026 0.072
SDC4 SDC4: Syndecan-4 precursor 0.026 0.033
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.026 0.166
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.026 0.032
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.026 0.073
GABRR1 N/A 0.026 0.075
SCTR SCTR: Secretin receptor precursor 0.026 0.033
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.026 0.032
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.026 0.113
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.026 0.126
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.026 0.029
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.026 0.202
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.026 0.065
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.026 0.081
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.026 0.100
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.025 0.065
SOS1 SOS1: Son of sevenless homolog 1 0.025 0.064
STAT2 STAT2: Signal transducer and activator of transcription 2 0.025 0.902
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.025 0.731
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.025 0.577
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.025 0.808
0.572
Total Score 10.30