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Evidence of Interaction Between CBL and YES1

The interaction score between CBL and YES1 is 80.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between CBL and YES1 = -0.03

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology
OrganismCBL OrthologueYES1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm Q19019 0.232 Q9BKW3 0.47

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.22E-3
Domains Domains present in CBL and YES1:
Domains in CBLDomains in YES1
IPR001841 Zn-finger, RING
IPR000449 Ubiquitin-associated domain
IPR000980 SH2 motif
IPR000217 Tubulin
IPR003153 Adaptor protein Cbl, N-terminal
IPR011992 EF-Hand_type.
IPR013090 Phospholip_A2_AS.
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR001452 SH3
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in CBL and YES1 are listed below.

Domain 1Domain 2Chi Square
IPR000980 SH2 motif IPR008266 Tyrosine protein kinase, active site 383.26
IPR000980 SH2 motif IPR001245 Tyrosine protein kinase 238.73
IPR000980 SH2 motif IPR000719 Protein kinase 82.1364
IPR000980 SH2 motif IPR011009 Protein kinase-like 59.6059
IPR000980 SH2 motif IPR001452 SH3 59.5667
IPR000980 SH2 motif IPR000980 SH2 motif 36.445
IPR003153 Adaptor protein Cbl, N-terminal IPR000980 SH2 motif 26.7596
IPR003153 Adaptor protein Cbl, N-terminal IPR001452 SH3 20.2778
IPR001841 Zn-finger, RING IPR001452 SH3 18.8486
IPR001841 Zn-finger, RING IPR008266 Tyrosine protein kinase, active site 16.2425
IPR001841 Zn-finger, RING IPR011009 Protein kinase-like 15.6712
IPR011992 EF-Hand_type. IPR000719 Protein kinase 15.5567
IPR001841 Zn-finger, RING IPR001245 Tyrosine protein kinase 15.1425
IPR001841 Zn-finger, RING IPR000719 Protein kinase 14.0542
IPR003153 Adaptor protein Cbl, N-terminal IPR008266 Tyrosine protein kinase, active site 13.6309
IPR011992 EF-Hand_type. IPR001452 SH3 11.7553
IPR001841 Zn-finger, RING IPR000980 SH2 motif 9.93803
IPR011992 EF-Hand_type. IPR011009 Protein kinase-like 9.34155
IPR003153 Adaptor protein Cbl, N-terminal IPR001245 Tyrosine protein kinase 9.19853
IPR011992 EF-Hand_type. IPR001245 Tyrosine protein kinase 6.38624
IPR011992 EF-Hand_type. IPR000980 SH2 motif 5.54712
IPR003153 Adaptor protein Cbl, N-terminal IPR000719 Protein kinase 3.06419
IPR003153 Adaptor protein Cbl, N-terminal IPR011009 Protein kinase-like 3.04324
IPR011992 EF-Hand_type. IPR008266 Tyrosine protein kinase, active site 1.24952
IPR000449 Ubiquitin-associated domain IPR000980 SH2 motif 0.609113
IPR000217 Tubulin IPR011009 Protein kinase-like 0.524874
IPR000449 Ubiquitin-associated domain IPR011009 Protein kinase-like 0.41941
IPR000449 Ubiquitin-associated domain IPR001245 Tyrosine protein kinase 0.348773
IPR000449 Ubiquitin-associated domain IPR001452 SH3 0.223539
IPR000217 Tubulin IPR001452 SH3 0.17131
IPR000217 Tubulin IPR008266 Tyrosine protein kinase, active site 0.0503676
IPR000217 Tubulin IPR000980 SH2 motif 0.0425012
IPR000217 Tubulin IPR000719 Protein kinase 0.0254403
IPR000449 Ubiquitin-associated domain IPR008266 Tyrosine protein kinase, active site 0.00515077
IPR000449 Ubiquitin-associated domain IPR000719 Protein kinase 0.00138935
IPR000217 Tubulin IPR001245 Tyrosine protein kinase 0.00033966

The background colour of the table refers to:

  • Blue Domain is only present in CBL
  • Yellow Domain is only present in YES1
  • Green Domain is present in both CBL and YES1

 0.980
Post-translational Modifications

Protein: CBL

PTMResidueReference
Phosphorylation 371 PubMed, HPRD
Phosphorylation 619 PubMed, HPRD
Phosphorylation 623 PubMed, HPRD
Phosphorylation 639 PubMed, HPRD
Phosphorylation 642 PubMed, HPRD
Phosphorylation 667 PubMed, HPRD
Phosphorylation 669 PubMed, HPRD
Phosphorylation 674 PubMed, HPRD
Phosphorylation 675 PubMed, HPRD
Phosphorylation 700 PubMed, HPRD
Phosphorylation 731 PubMed, HPRD
Phosphorylation 774 PubMed, HPRD
Phosphoserine 669 HPRD
Phosphotyrosine 371 PubMed, HPRD
Phosphotyrosine 674 HPRD
Phosphotyrosine 700 HPRD
Phosphotyrosine 774 HPRD

Protein: YES1

PTMResidueReference
Phosphorylation 426 PubMed, HPRD
Phosphotyrosine 536 HPRD
Localisation

Protein: CBL

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD

Protein: YES1

LocalisationReference
Cytosol HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between CBL and YES1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CBL andYES1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CBL has 1376 interactors and YES1 has 1392 interactors of which there are 906 common interactors.

Common InteractorName of Common InteractorScore for CBL-Interactor (?)Score for YES1-Interactor (?)
ZAP70 ZAP70: Uncharacterized protein ZAP70 277.00 0.975
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 214.00 0.655
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 173.00 1.33
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 137.00 0.808
SORBS3 SORBS3, SCAM1: Vinexin 43.20 0.225
NCK2 NCK2: Cytoplasmic protein NCK2 30.80 0.874
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 8.34 1.17
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 5.94 0.156
GRAP GRAP: GRB2-related adapter protein 2.13 0.140
SHC2 N/A 1.29 0.0258
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 1.20 0.775
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 1.13 1.20
NEDD4L N/A 1.07 0.119
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 1.01 1.07
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.902 0.975
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.878 1.17
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.878 1.30
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.878 1.17
SYK SYK: Tyrosine-protein kinase SYK 0.808 0.775
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.731 1.50
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.731 0.859
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.655 0.775
LYN LYN: Tyrosine-protein kinase Lyn 0.655 0.694
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.655 0.872
CSK CSK: Tyrosine-protein kinase CSK 0.655 0.694
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.655 0.859
HCK N/A 0.655 0.694
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.655 0.694
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.644 2.42
BMX N/A 0.644 0.859
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.617 0.617
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.617 0.617
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.617 0.617
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.617 0.617
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.577 0.775
JAK1 0.577 0.975
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.577 0.975
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.577 1.35
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.577 0.874
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.553 0.553
FLT4 VEGFR3 long form 0.553 0.553
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.540 0.980
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.540 0.980
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.540 0.980
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.484 0.484
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.484 0.980
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.484 0.980
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.484 0.878
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.484 0.980
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.445 1.01
ALK ALK: ALK tyrosine kinase receptor precursor 0.445 0.361
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.445 0.577
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.445 0.655
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.445 0.577
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.403 0.731
MET MET: Hepatocyte growth factor receptor precursor 0.403 1.13
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.361 1.01
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.361 0.808
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.361 0.520
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.361 0.655
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.320 0.902
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.318 0.520
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.318 0.655
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.318 0.644
INSR INSR: Insulin receptor precursor 0.318 0.577
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.318 0.655
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.318 0.577
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.318 0.902
KIT KIT: Mast/stem cell growth factor receptor precursor 0.318 0.808
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.286 0.655
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.286 1.33
PRKAA1 N/A 0.251 0.123
TNK1 TNK1: Non-receptor tyrosine-protein kinase TNK1 0.237 0.237
DYRK3 N/A 0.225 0.136
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.217 0.265
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.191 0.098
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.191 0.109
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.191 0.123
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.171 0.191
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.171 0.152
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.165
MAPK15 N/A 0.165 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.165 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.165 0.165
MAPKAPK5 N/A 0.165 0.165
PPEF1 N/A 0.165 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.165 0.148
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.165 0.165
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.156 0.030
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.087
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.152 0.109
PLEK PLEK, P47: Pleckstrin 0.152 0.065
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.152 0.072
STAT2 STAT2: Signal transducer and activator of transcription 2 0.152 0.581
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.152 0.109
ROCK1 ROCK1: Rho-associated protein kinase 1 0.152 0.123
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.152 0.081
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.152 0.123
STK16 N/A 0.152 0.191
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.152 0.123
IRS1 IRS1: Insulin receptor substrate 1 0.152 0.251
SCML2 SCML2: Sex comb on midleg-like protein 2 0.152 0.100
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.152 0.098
STAM2 STAM2: Signal transducing adapter molecule 2 0.148 0.110
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.148 0.098
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.148 0.165
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.148 0.098
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.148 0.098
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.148 0.148
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.148 0.109
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.878
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.148 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.148 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.148
ELMO1 N/A 0.148 0.148
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.148 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.148 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.148 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.148 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.148 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.148 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.148 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.148 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.148 0.098
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.148 0.098
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.148
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.145 0.197
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.143 0.244
FYN N/A 0.143 0.197
FGFR2 N/A 0.140 0.217
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.140 0.192
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.030
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.136 0.073
SOS1 SOS1: Son of sevenless homolog 1 0.136 0.073
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.136 0.072
CDK7 CDK7, MO15: Cell division protein kinase 7 0.136 0.225
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.136 0.088
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.136 0.109
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.136 0.136
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.136 0.097
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.136 0.088
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.136 0.136
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.136 0.088
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.136 0.110
TTN N/A 0.136 0.110
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.136 0.110
WEE1 WEE1: Wee1-like protein kinase 0.136 0.123
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.136 0.136
RYK RYK, JTK5A: Tyrosine-protein kinase RYK precursor 0.129 0.330
GRLF1 N/A 0.127 0.152
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.126 0.195
RPL11 RPL11: 60S ribosomal protein L11 0.126 0.078
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.123 0.109
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.123 0.098
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.123 0.0425
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.123 0.098
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.123 0.065
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.123 0.152
DAPK2 DAPK2: Death-associated protein kinase 2 0.123 0.123
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.123 0.098
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.123 0.191
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.123 0.123
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.123 1.13
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.123 0.109
LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 0.116 0.128
INSRR INSRR, IRR: Insulin receptor-related protein precursor 0.116 0.115
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.110 0.088
CDK2 CDK2: Cell division protein kinase 2 0.110 0.110
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.110 0.097
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.110 0.152
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.110 0.110
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.110 0.152
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.110 0.097
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.110 0.225
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.110 0.110
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.110 0.110
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.110 0.136
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.110 0.110
CDK4 CDK4: Cell division protein kinase 4 0.110 0.152
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.110 0.110
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.110 0.110
CXorf9 N/A 0.110 0.098
CDK6 CDK6: Cell division protein kinase 6 0.110 0.109
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.110 0.109
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.110 0.073
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.110 0.110
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.110 0.090
ATM ATM: Serine-protein kinase ATM 0.110 0.097
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.110 0.110
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.110 0.097
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.110 0.136
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.110 0.110
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.110 0.171
FNBP1 N/A 0.110 2.77
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.110 0.136
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.110 0.110
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.110 0.097
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.110 0.097
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.110 0.110
STK10 STK10: Uncharacterized protein STK10 0.110 0.097
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.110 0.097
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.110 0.088
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.110 0.090
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.110 0.110
DOK1 DOK1: Docking protein 1 0.110 0.123
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.110 0.110
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.110 0.136
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.110 0.097
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.110 0.058
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.110 0.097
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.110 0.110
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.110 0.097
STAT4 STAT4: Signal transducer and activator of transcription 4 0.110 0.577
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.110 0.110
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.109 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
CASP9 CASP9, MCH6: Caspase-9 precursor 0.109 0.028
CASP8 CASP8, MCH5: Caspase-8 precursor 0.109 0.083
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
MAP2K5 N/A 0.109 0.165
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.109 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 1.30
PSCD2 N/A 0.109 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.109 0.165
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 1.30
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 1.30
CNN2 CNN2: Calponin-2 0.109 0.148
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.109 0.072
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.109 0.123
GAB1 GAB1: GRB2-associated-binding protein 1 0.109 0.152
IRS2 IRS2: Insulin receptor substrate 2 0.109 0.098
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.109 0.123
GAB2 N/A 0.109 0.098
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.109 0.109
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.123
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.109 0.081
TP73 TP73, P73: Tumor protein p73 0.109 0.081
CDKL5 N/A 0.109 0.098
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.109 0.123
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.109 0.109
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.109 0.581
ETS2 ETS2: Protein C-ets-2 0.109 0.081
AMHR2 AMHR2, AMHR: Anti-Muellerian hormone type-2 receptor precursor 0.105 0.200
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.100 0.123
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.100 0.859
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.098 0.126
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.098 0.123
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.098 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.165
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.098 0.025
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.098 1.30
ARHGEF7 N/A 0.098 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.148
STAT3 0.098 1.17
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.098 0.028
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.098 0.165
MYO18A 0.098 0.028
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.097 0.088
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.097 0.073
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.097 0.110
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.097 0.065
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.097 0.064
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.097 0.029
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.097 0.520
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.097 0.110
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.097 0.109
DAB1 DAB1: Disabled homolog 1 0.097 0.097
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.097 0.064
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.097 0.073
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.097 0.097
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.097 0.110
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.097 0.225
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.097
RPS6KB1 N/A 0.097 0.136
CDK5 CDK5: Cell division protein kinase 5 0.097 0.097
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.097 0.110
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.097 0.171
MYO3A MYO3A: Myosin IIIA 0.097 0.098
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.097 0.097
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.097 0.655
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.097 0.097
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.110
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.097 0.110
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.097 0.110
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.097 0.225
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.097 0.110
RIN1 RIN1: Ras and Rab interactor 1 0.097 1.07
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.097 0.110
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.097 0.136
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.097 0.097
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.097 0.110
ROR2 ROR2, NTRKR2: Tyrosine-protein kinase transmembrane receptor ROR2 precursor 0.094 0.128
MUSK MUSK: Muscle, skeletal receptor tyrosine protein kinase precursor 0.094 0.143
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.0924 0.143
STYK1 STYK1, NOK: Tyrosine protein-kinase STYK1 0.0924 0.162
RET urf-ret: Urf-ret protein 0.0924 0.162
TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 0.0924 0.129
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.090 0.046
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.090 0.136
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.090 0.225
PSCD4 PSCD4, CYT4: Cytohesin-4 0.090 0.088
CD2AP CD2AP: CD2-associated protein 0.090 0.110
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.090 0.694
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.090 0.136
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.090 0.088
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.090 0.171
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.090 0.275
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.088 0.097
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.088 0.064
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.088 0.097
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.088 0.110
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.088 0.110
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.088 0.110
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.088 0.058
HES6 HES6: Transcription cofactor HES-6 0.083 0.049
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.083
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.04
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.04
MCF2 MCF2, DBL: Proto-oncogene DBL 0.081 0.123
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.081 0.062
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.859
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.081 0.123
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.098
LIMK2 LIMK2: LIM domain kinase 2 0.081 0.152
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.081 0.975
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.081 0.775
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.081 0.055
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.081 0.109
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.075 0.025
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.075 0.179
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.073 4.67
THOC1 THOC1, HPR1: THO complex subunit 1 0.073 0.056
RASA3 RASA3: Ras GTPase-activating protein 3 0.073 0.136
WASPIP N/A 0.073 4.67
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.073 0.032
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.073 0.110
LCP1 LCP1, PLS2: Plastin-2 0.073 0.088
STAT6 STAT6: Signal transducer and activator of transcription 6 0.073 0.694
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.073 0.136
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.073 0.097
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.073 0.097
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.073 4.67
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.073 0.136
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.073 0.152
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.073 0.110
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.073 0.136
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.073 0.026
VAV1 VAV1, VAV: Proto-oncogene vav 0.073 0.694
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.073 0.191
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.073 0.110
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.073 1.07
PLD1 PLD1: Phospholipase D1 0.073 0.171
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.073 5.18
APS SH2B2, APS: SH2B adapter protein 2 0.073 0.872
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 1.20
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.072 0.191
SPTAN1 N/A 0.072 0.109
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.072 0.109
FLNA FLNA, FLN, FLN1: Filamin-A 0.072 0.032
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.072 0.775
GAS2 GAS2: Growth arrest-specific protein 2 0.072 0.026
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.072 0.032
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.110
VASP VASP: Vasodilator-stimulated phosphoprotein 0.072 0.109
RYR1 0.071 0.046
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.071 0.046
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.069 0.032
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.069 0.037
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.0688 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.0688 0.098
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.0688 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.0688 0.109
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.0688 0.0688
KIR3DL1 N/A 0.0688 0.109
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.0688 0.0688
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.0688 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.0688 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.0688 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.0688 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.0688 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.0688 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.0688 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.0688 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.0688 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.0688 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.0688 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.0688 0.109
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.0688 0.049
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.0688 0.109
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.0688 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.0688 0.109
FN1 N/A 0.0688 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.0688 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.0688 0.109
CTTN CTTN, EMS1: Src substrate cortactin 0.065 7.83
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.065 0.055
COBL N/A 0.065 0.109
CNN3 CNN3: Calponin-3 0.065 0.171
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.064 0.136
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.064 0.770
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.064 0.110
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.275
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.064 0.136
PLD2 PLD2: Phospholipase D2 0.064 0.225
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.064 0.097
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.064 0.097
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.064 0.078
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.064 0.109
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.064 0.097
PARVA PARVA, MXRA2: Alpha-parvin 0.064 0.029
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.064 0.694
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.064 0.032
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.064 0.109
CRKL CRKL: Crk-like protein 0.064 1.07
VIL2 N/A 0.064 0.097
RDX RDX: Radixin 0.064 0.275
TLN1 TLN1: Uncharacterized protein TLN1 0.064 0.136
TLN2 TLN2: Uncharacterized protein TLN2 0.064 0.088
MSN MSN: Moesin 0.064 0.136
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.064 0.097
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.064 0.088
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.064 0.088
CCR5 CCR5: CCR5 receptor (Fragment) 0.063 0.0727
LILRB1 N/A 0.063 0.065
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.063 0.0727
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.063 0.072
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.063 0.100
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.063 0.081
PRLR PRLR: Prolactin receptor precursor 0.063 0.072
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.063 0.126
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.063 0.072
ANXA9 ANXA9, ANX31: Annexin A9 0.063 0.030
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.063 0.072
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.063 0.072
IRF3 IRF3: Interferon regulatory factor 3 0.062 0.032
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.029
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.062 0.026
CNTN1 CNTN1: Contactin-1 precursor 0.062 0.109
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.062 0.098
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.062 0.098
KCNQ2 KCNQ2: Potassium voltage-gated channel subfamily KQT member 2 0.062 0.030
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.062 0.109
BSG N/A 0.062 0.109
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.062 0.0688
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.062 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.062 0.098
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.062 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.062 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.062 0.109
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.062 0.098
KCNH2 KCNH2, ERG, ERG1, HERG, HERG1: Potassium voltage-gated channel subfamily H membe 0.062 0.030
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.058 0.225
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.058 0.136
PSD TYL: TYL protein 0.058 0.088
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.058 0.097
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.058 0.136
NEO1 NEO1, NGN: Neogenin precursor 0.057 0.064
DCC DCC: Netrin receptor DCC precursor 0.057 0.090
GLRA1 N/A 0.057 0.041
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.057 0.100
GRK7 GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor 0.056 0.056
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.056 0.056
TP53 TP53, P53: Cellular tumor antigen p53 0.056 0.037
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.056 0.033
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.056 0.029
HES1 HES1, HL, HRY: Transcription factor HES-1 0.056 0.067
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.056 0.029
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.053 0.0338
FBXO4 FBXO4, FBX4: F-box only protein 4 0.052 0.028
PTPRA N/A 0.051 0.051
MAPK7 MAPK7, ERK4, ERK5, PRKM7: Mitogen-activated protein kinase 7 0.051 0.046
IGHD N/A 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
PRKCD PRKCD: Protein kinase C delta type 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
NCAM1 N/A 0.051 0.051
GSK3B GSK3B: Glycogen synthase kinase-3 beta 0.051 0.051
MAP4K4 N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.617
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.617
C9orf88 N/A 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
UBAP2L N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.617
GRB10 N/A 0.051 0.617
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
HLA-A N/A 0.051 0.051
MAPK11 MAPK11, PRKM11, SAPK2: Mitogen-activated protein kinase 11 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
RAPH1 N/A 0.051 0.051
CDC42EP1 CDC42EP1, BORG5, CEP1, MSE55: Cdc42 effector protein 1 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
IGHG3 N/A 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
CHUK CHUK, IKKA, TCF16: Inhibitor of nuclear factor kappa-B kinase subunit alpha 0.051 0.051
IGHM N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
IGHA1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
MARK2 N/A 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
GPA33 GPA33: Cell surface A33 antigen precursor 0.051 0.081
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.051 0.072
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.051 0.105
IL9R IL9R: Interleukin-9 receptor precursor 0.051 0.126
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.051 0.065
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.051 0.072
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.051 0.065
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.051 0.0727
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.051 0.0727
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.051 0.065
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.051 0.072
GHR GHR: Growth hormone receptor precursor 0.051 0.100
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.051 0.100
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.051 0.072
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.051 0.057
SORL1 SORL1: Sortilin-related receptor precursor 0.051 0.058
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.051 0.065
PVR PVR, PVS: Poliovirus receptor precursor 0.051 0.126
ITGB4 N/A 0.051 0.166
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.051 0.065
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.051 0.081
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.051 0.072
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.051 0.065
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.051 0.065
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.051 0.081
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.051 0.081
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.051 0.128
EPOR EPOR: Erythropoietin receptor precursor 0.051 0.072
EGF EGF: Pro-epidermal growth factor precursor 0.051 0.081
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.051 0.100
CSPG2 N/A 0.051 0.045
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.051 0.081
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.051 0.0727
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.051 0.105
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.051 0.065
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.051 0.065
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.051 0.065
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.051 0.081
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.051 0.037
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.051 0.274
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.051 0.065
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.051 0.065
GABRR1 N/A 0.051 0.037
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.051 0.065
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.051 0.100
ANXA3 ANXA3, ANX3: Annexin A3 0.051 0.061
F3 F3: Tissue factor precursor 0.051 0.126
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.051 0.032
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.051 0.077
FLII FLII, FLIL: Protein flightless-1 homolog 0.051 0.035
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.165
CASP6 CASP6, MCH2: Caspase-6 precursor 0.049 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.049 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.049 0.028
AXIN1 0.049 0.028
CASP14 CASP14: Caspase-14 precursor 0.049 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.049 0.083
YWHAG YWHAG: 14-3-3 protein gamma 0.049 0.028
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.049 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.165
WWC1 WWC1, KIAA0869: WW domain-containing protein 1 0.049 0.026
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.049 0.033
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.049 0.056
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.047 0.038
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.047 0.044
GIT2 N/A 0.047 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.047 0.109
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.051
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.051
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
LMO7 N/A 0.046 0.046
SRPK1 SRPK1: Serine/threonine-protein kinase SRPK1 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.553
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.051
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
TLK2 TLK2: Serine/threonine-protein kinase tousled-like 2 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.051
IKBKE IKBKE, IKKE, IKKI, KIAA0151: Inhibitor of nuclear factor kappa-B kinase subunit 0.046 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.553
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
DLG2 DLG2: Disks large homolog 2 0.046 0.041
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.046 0.058
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.046 0.073
SLC9A7 SLC9A7, NHE7: Sodium/hydrogen exchanger 7 0.046 0.033
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.046 0.071
SLC9A3 SLC9A3, NHE3: Sodium/hydrogen exchanger 3 0.046 0.026
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.046 0.041
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.046 0.065
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.046 0.090
AKAP1 AKAP1, AKAP149, PRKA1: A kinase anchor protein 1, mitochondrial precursor 0.046 0.025
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.0453 0.055
FHL1 FHL1, SLIM1: Four and a half LIM domains protein 1 0.0453 0.026
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.045 0.065
FADD FADD, MORT1: Protein FADD 0.045 0.0453
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.045 0.045
CRLF3 N/A 0.045 0.0727
SLC9A1 SLC9A1, APNH1, NHE1: Sodium/hydrogen exchanger 1 0.045 0.032
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.045 0.065
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.045 0.074
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.045 0.105
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.045 0.072
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.045 0.063
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.045 0.0727
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.045 0.0794
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.045 0.065
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.045 0.063
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.045 0.081
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.045 0.0727
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.045 0.126
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.045 0.081
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.045 0.065
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.045 0.045
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.045 0.072
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.045 0.046
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.045 0.126
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.045 0.045
CD7 CD7: T-cell antigen CD7 precursor 0.045 0.081
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.045 0.065
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.045 0.081
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.045 0.100
RYR2 RYR2: Ryanodine receptor 2 0.045 0.045
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.045 0.126
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.045 0.202
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.044 0.025
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.044 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.044 0.148
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.044 0.028
LMO6 LMO6: LIM domain only protein 6 0.044 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.044 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.044 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
DCTN1 DCTN1: Dynactin subunit 1 0.044 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.028
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.028
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.042 0.034
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.041 0.081
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.041
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.041 0.105
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.041 0.072
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.041 0.056
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.041 0.097
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.041 0.029
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.041 0.029
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.041 0.037
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.041 0.090
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.041 0.064
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.041 0.064
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.041 0.057
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.037
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.041 0.113
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.041 0.105
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.041 0.114
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.041 0.072
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.041 0.090
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.041 0.148
MCOLN1 MCOLN1, ML4, MSTP080: Mucolipin-1 0.041 0.037
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.041 0.126
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.041 0.155
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.041 0.094
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.052
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.039 0.032
CDC42EP3 CDC42EP3, BORG2, CEP3: Cdc42 effector protein 3 0.038 0.047
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.038 0.030
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.038 0.047
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.037 0.058
RAB32 RAB32: Ras-related protein Rab-32 0.037 0.051
FUBP1 N/A 0.037 0.062
S100A3 S100A3, S100E: Protein S100-A3 0.037 0.152
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.098
PTPRZ1 N/A 0.037 0.072
TNC TNC, HXB: Tenascin precursor 0.037 0.148
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.037 0.041
GLRB GLRB: Glycine receptor subunit beta precursor 0.037 0.029
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.037 0.073
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.036 0.165
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.036 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.036 0.148
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.035 0.0818
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.035 0.110
CCNB1 Cyclin B1 0.035 0.041
CCNH CCNH: Cyclin-H 0.035 0.041
TSHR N/A 0.035 0.041
NFIB N/A 0.034 0.027
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.034 0.030
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.034 0.030
TNN TNN: Tenascin-N precursor 0.034 0.042
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.0338 0.034
MAP4 MAP4: Microtubule-associated protein 4 0.0338 0.0253
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0338 0.038
CNN1 CNN1: Calponin-1 0.0338 0.042
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.034 0.049
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.034 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.034 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.034 0.049
MAL2 MAL2: Protein MAL2 0.034 0.034
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.034 0.049
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.034 0.109
DNASE1 DNASE1, DNL1, DRNI: Deoxyribonuclease-1 precursor 0.034 0.034
WWC2 WW and C2 domain containing 2 0.033 0.0425
TBCE TBCE: Tubulin-specific chaperone E 0.033 0.029
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.139
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.033 0.056
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.033 0.029
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.033 0.049
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.033 0.044
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.033 0.114
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.033 0.110
GMIP GMIP: GEM-interacting protein 0.033 0.097
YWHAQ YWHAQ: 14-3-3 protein theta 0.032 0.032
LPP LPP: Lipoma-preferred partner 0.032 0.032
LIMS1 N/A 0.032 0.032
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.123
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.191
ZYX ZYX: Zyxin 0.032 0.026
OCLN OCLN: Occludin 0.031 0.039
F5 F5: Coagulation factor V precursor 0.031 0.041
NUAK1 NUAK1, ARK5, KIAA0537: NUAK family SNF1-like kinase 1 0.030 0.030
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.044
ATRN N/A 0.030 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.030 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.030 0.044
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.030 0.044
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.030 0.123
PHB2 PHB2, BAP, REA: Prohibitin-2 0.030 0.055
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.030 0.062
S100B S100B: Protein S100-B 0.029 0.109
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.029 0.064
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.029 0.097
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.026
YWHAE YWHAE: 14-3-3 protein epsilon 0.029 0.029
PARD3 N/A 0.029 0.052
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.029 0.056
LIMA1 LIMA1, EPLIN, PP624, SREBP3: LIM domain and actin-binding protein 1 0.029 0.063
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.055
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.029 0.029
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.225
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.029 0.824
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.029 0.049
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.029 0.097
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
ROS1 ROS1: Proto-oncogene tyrosine-protein kinase ROS precursor 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
NULL N/A 0.0288 0.0288
MUSK MUSK: MUSK protein 0.0288 0.0288
NULL Tyrosine kinase 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
NTRK3 NTRK3, TRKC: NT-3 growth factor receptor precursor 0.0288 0.0288
NTRK3 N/A 0.0288 0.0288
TTN TTN: Uncharacterized protein TTN (Fragment) 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
TESK2 TESK2: Dual specificity testis-specific protein kinase 2 0.0288 0.0288
DDR2 DDR2, NTRKR3, TKT, TYRO10: Discoidin domain-containing receptor 2 precursor 0.0288 0.0288
NULL N/A 0.0288 0.0288
AATK apoptosis-associated tyrosine kinase 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
PHLDB2 N/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
BID BID: BH3-interacting domain death agonist 0.028 0.049
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.109
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
HPN HPN, TMPRSS1: Serine protease hepsin 0.028 0.032
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.028 0.073
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.027 0.063
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.027 0.088
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.027 0.114
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
FAM43A N/A 0.027 0.027
CDC2L2 N/A 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
NEK4 NEK4, STK2: Serine/threonine-protein kinase Nek4 0.027 0.027
TRIM9 TRIM9, KIAA0282, RNF91: Tripartite motif-containing protein 9 0.027 0.027
OSBPL9 N/A 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
MID2 N/A 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
SHANK1 SHANK1: SH3 and multiple ankyrin repeat domains protein 1 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
ALS2CR7 ALS2CR7: Serine/threonine-protein kinase ALS2CR7 0.027 0.027
FANK1 FANK1, HSD13, UNQ6504/PRO21382: Fibronectin type 3 and ankyrin repeat domains pr 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
CASKIN1 N/A 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
RIPK5 RIPK5, KIAA0472, HDCMD38P, RIP5, SGK496: Receptor-interacting serine/threonine-p 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
CAMKK1 CAMKK1, CAMKKA: Calcium/calmodulin-dependent protein kinase kinase 1 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
STK35 STK35, CLIK1, PDIK1: Serine/threonine-protein kinase 35 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
NEK11 NEK11: Serine/threonine-protein kinase Nek11 0.027 0.027
PPP1R9A PPP1R9A, KIAA1222: Neurabin-1 0.027 0.027
UBL7 UBL7, BMSCUBP, SB132: Ubiquitin-like protein 7 0.027 0.027
PDIK1L PDIK1L, CLIK1L: Serine/threonine-protein kinase PDIK1L 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0263 0.035
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.0263 0.098
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.0263 0.109
MT3 MT3: Metallothionein-3 0.026 0.033
PMP2 PMP2: Myelin P2 protein 0.026 0.056
MAGED2 N/A 0.026 0.0425
FES N/A 0.0258 0.0258
KIF23 N/A 0.026 0.0453
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.026 0.057
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.025 0.072
RAP1GA1 N/A 0.025 0.037
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.025 0.037
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.025 0.037
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.025 0.072
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.025 0.0453
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.025 0.030
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.148
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.025 0.044
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.148
PRKCB1 N/A 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.098
BCOR N/A 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
CREB1 CREB1: cAMP response element-binding protein 0.025 0.044
CAMK2A N/A 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.366
NIPBL N/A 0.025 0.025
CAMKK1 N/A 0.025 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.025 0.044
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
MAP2K3 N/A 0.025 0.025
CCNT2 CCNT2: Cyclin-T2 0.025 0.044
GRK6 N/A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.028
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
0.347
Total Score 80.00