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Evidence of Interaction Between NGFR and STAT5A

The interaction score between NGFR and STAT5A is 4.04.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between NGFR and STAT5A = -0.15

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.48E-3
Orthology N/A N/A
Domains Domains present in NGFR and STAT5A:
Domains in NGFRDomains in STAT5A
IPR008262 Lipase, active site
IPR001368 TNFR/CD27/30/40/95 cysteine-rich region
IPR011029 DEATH-like
IPR000488 Death domain
IPR013032 IPR006209.
IPR008967 p53-like transcription factor, DNA-binding
IPR000980 SH2 motif
IPR001217 STAT protein
IPR011992 EF-Hand_type.
IPR012345 STAT_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in NGFR and STAT5A are listed below.

Domain 1Domain 2Chi Square
IPR013032 IPR006209. IPR011992 EF-Hand_type. 10.5453
IPR013032 IPR006209. IPR000980 SH2 motif 10.3113
IPR011029 DEATH-like IPR000980 SH2 motif 5.80398
IPR011029 DEATH-like IPR011992 EF-Hand_type. 4.03666
IPR001368 TNFR/CD27/30/40/95 cysteine-rich region IPR000980 SH2 motif 1.5846
IPR000488 Death domain IPR011992 EF-Hand_type. 0.879117
IPR000488 Death domain IPR000980 SH2 motif 0.449275

The background colour of the table refers to:

  • Blue Domain is only present in NGFR
  • Yellow Domain is only present in STAT5A
  • Green Domain is present in both NGFR and STAT5A

 0.049
Post-translational Modifications

Protein: NGFR

PTMResidueReference
Phosphorylation 303 PubMed, HPRD

Protein: STAT5A

PTMResidueReference
Dephosphorylation 694 PubMed, HPRD
Phosphorylation 694 PubMed, HPRD
Phosphorylation 726 PubMed, HPRD
Phosphorylation 780 PubMed, HPRD
Phosphotyrosine 694 PubMed, HPRD
Localisation

Protein: NGFR

LocalisationReference
Plasma membrane HPRD

Protein: STAT5A

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between NGFR and STAT5A that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between NGFR andSTAT5A. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , NGFR has 1053 interactors and STAT5A has 1739 interactors of which there are 523 common interactors.

Common InteractorName of Common InteractorScore for NGFR-Interactor (?)Score for STAT5A-Interactor (?)
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 1.30 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 1.30 0.049
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 1.20 0.037
CASP8 CASP8, MCH5: Caspase-8 precursor 0.980 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.980 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.980 0.028
FADD FADD, MORT1: Protein FADD 0.975 0.075
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.859 0.046
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.859 0.0453
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.859 0.0453
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.859 0.072
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.859 0.075
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.775 0.061
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.731 0.0425
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.731 0.063
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.731 0.372
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.731 0.251
CIITA CIITA, MHC2TA: MHC class II transactivator 0.644 0.0425
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.644 0.171
THOC1 THOC1, HPR1: THO complex subunit 1 0.581 0.188
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.581 0.155
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.581 0.046
RPS10 RPS10: 40S ribosomal protein S10 0.581 0.063
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.581 0.052
PSMD12 PSMD12: 26S proteasome non-ATPase regulatory subunit 12 0.405 0.037
ITGB4 N/A 0.251 0.065
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.191 0.577
IRAK3 IRAK3: Interleukin-1 receptor-associated kinase 3 0.174 0.032
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.878
ATRN N/A 0.165 0.044
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.165 0.049
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.878
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.165 0.049
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.049
JAG2 JAG2: Jagged-2 precursor 0.165 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.165 0.098
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.152 0.577
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.152 0.520
IRAK4 IRAK4: Interleukin-1 receptor-associated kinase 4 0.143 0.044
RIPK2 RIPK2, CARDIAK, UNQ277/PRO314/PRO34092, RICK, RIP2: Receptor-interacting serine/ 0.143 0.0308
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.126 0.046
EGF EGF: Pro-epidermal growth factor precursor 0.123 0.072
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.123 0.029
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.123 0.520
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.123 0.026
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.123 0.029
DCC DCC: Netrin receptor DCC precursor 0.123 0.064
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.577
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.123 0.586
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.586
TSHR N/A 0.123 0.029
NOTCH4 N/A 0.123 0.029
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.123 0.586
NEO1 NEO1, NGN: Neogenin precursor 0.123 0.052
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.109 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.109 0.025
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.109 0.062
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.109 0.075
CASP14 CASP14: Caspase-14 precursor 0.109 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.109 0.083
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.109 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.109 0.025
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.109 0.034
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.484
CASP6 CASP6, MCH2: Caspase-6 precursor 0.109 0.028
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.109 0.090
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.109 0.0818
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.109 0.465
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.109 0.586
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.109 0.072
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.109 0.029
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.109 0.577
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.109 0.029
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.109 0.058
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.109 0.072
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.109 0.072
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.109 0.037
TNC TNC, HXB: Tenascin precursor 0.109 0.058
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.065
HPN HPN, TMPRSS1: Serine protease hepsin 0.109 0.029
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.581
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.098 0.202
SORL1 SORL1: Sortilin-related receptor precursor 0.098 0.166
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.098 0.074
ITGAE ITGAE: Integrin alpha-E precursor 0.098 0.027
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.098 0.067
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.098 0.202
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.098 0.181
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.098 0.027
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.083 0.109
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.083 0.878
BSG N/A 0.083 0.098
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.148
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.083 0.878
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.083 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.083 0.098
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.083 0.109
CNTN1 CNTN1: Contactin-1 precursor 0.083 0.098
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.083 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.083 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.083 0.980
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.083 0.098
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.083 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.083 0.109
FN1 N/A 0.083 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.083 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.083 0.109
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.081 0.110
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.081 0.041
DAB1 DAB1: Disabled homolog 1 0.081 0.110
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.081 0.045
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.081 0.045
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.081 0.171
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.081 0.045
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.081 0.127
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.081 0.191
FLII FLII, FLIL: Protein flightless-1 homolog 0.081 0.046
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.081 0.078
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.081 0.046
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.081 0.041
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.081 0.086
DAB2 DAB2, DOC2: Disabled homolog 2 0.081 0.097
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.081 0.041
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.080 0.520
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.077 0.072
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.077 0.065
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.075 0.062
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.072 0.037
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.072 0.123
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.072 0.046
CASP3 CASP3, CPP32: Caspase-3 precursor 0.072 0.046
CSPG2 N/A 0.072 0.0794
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.072 0.0425
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.072 0.0425
VWF VWF, F8VWF: von Willebrand factor precursor 0.072 0.041
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.072 0.032
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.318
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.072 0.037
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.072 0.041
THOP1 THOP1: Thimet oligopeptidase 0.072 0.029
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.072 0.035
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.0688 0.044
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.065 0.038
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.065 0.038
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.065 0.0425
FUBP1 N/A 0.065 0.260
TBCE TBCE: Tubulin-specific chaperone E 0.065 0.046
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.065 0.032
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.065 0.146
INSR INSR: Insulin receptor precursor 0.062 277.00
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.062 0.029
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.062 0.072
MET MET: Hepatocyte growth factor receptor precursor 0.062 0.519
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.062 0.065
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.062 0.655
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.062 600.00
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.062 0.654
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.062 0.072
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.062 0.099
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.062 0.065
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.062 0.081
IL9R IL9R: Interleukin-9 receptor precursor 0.062 0.081
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.057 0.694
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.057 0.123
PMP2 PMP2: Myelin P2 protein 0.057 0.044
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.057 0.775
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.055 0.0727
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.055 250.00
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.055 0.072
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.055 1.16E3
KIT KIT: Mast/stem cell growth factor receptor precursor 0.055 487.00
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.055 0.081
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.055 0.029
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.055 0.081
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.055 0.065
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.055 0.655
CD7 CD7: T-cell antigen CD7 precursor 0.055 0.126
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.055 0.166
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.055 0.126
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.055 0.065
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.055 0.064
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.055 0.058
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.055 0.081
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.055 0.065
PTPRZ1 N/A 0.055 0.058
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.055 0.0727
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.055 0.225
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.055 0.113
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.055 0.166
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.055 0.073
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.055 0.065
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.055 0.064
F3 F3: Tissue factor precursor 0.055 0.065
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.055 1.33
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.055 0.166
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.055 0.202
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.052 0.109
KIR3DL1 N/A 0.052 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.052 0.109
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.052 0.098
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.052 0.980
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.052 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.052 0.980
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.052 0.109
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.051 0.046
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.046
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
XRCC1 XRCC1: DNA-repair protein XRCC1 0.051 0.091
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.051 0.067
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.051 0.124
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.064
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.049 0.113
CRLF3 N/A 0.049 0.274
CD69 CD69: Early activation antigen CD69 0.049 0.027
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.049 0.275
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.049 0.202
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.049 0.202
CD44 N/A 0.049 0.061
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.049 0.097
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.049 0.166
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.049 0.148
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.165
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.049 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.148
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.165
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.049 0.025
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.049 1.17
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.049 0.148
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.049 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.049 0.025
MAPK15 N/A 0.049 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.049 0.148
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.049 563.00
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.165
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.148
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.165
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.148
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.049 0.075
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.049 0.0688
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.148
DSP DSP: Desmoplakin 0.049 0.049
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.148
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.049 0.075
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.049 1.30
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.049 0.148
STAT3 0.049 12.60
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.165
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.148
MAP2K5 N/A 0.049 0.165
GIT2 N/A 0.049 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.148
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.049 0.148
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.165
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.148
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.049 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.148
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
MAPKAPK5 N/A 0.049 0.165
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.048 0.586
STK16 N/A 0.0453 0.152
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.0453 0.110
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.0453 0.099
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.0453 0.097
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.0453 0.088
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.0453 0.088
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.0453 0.225
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.0453 0.088
PRPH PRPH, NEF4, PRPH1: Peripherin 0.0453 0.044
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.065
P4HB P4HB, ERBA2L, PDI, PDIA1, PO4DB: Protein disulfide-isomerase precursor 0.045 1.51
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.045 0.111
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.045 0.031
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.045 0.124
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.044 0.062
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.041 0.075
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.041 0.064
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.041 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.04 0.148
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
SNX3 N/A 0.04 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.04 1.17
NF2 NF2, SCH: Merlin 0.04 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.04 1.30
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.039 0.081
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.039 0.065
PRLR PRLR: Prolactin receptor precursor 0.039 0.065
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.039 0.064
TNN TNN: Tenascin-N precursor 0.038 0.030
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.037 0.088
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.037 0.110
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.037 0.225
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.037 0.225
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.037 0.097
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.099
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.037 0.097
CDK4 CDK4: Cell division protein kinase 4 0.037 0.275
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.037 0.088
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.037 0.056
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.037 0.041
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.037 0.171
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.037 0.109
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.037 0.136
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.097
GFAP GFAP: Glial fibrillary acidic protein 0.037 0.049
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.037 47.50
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.037 0.097
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.037 0.069
RIN1 RIN1: Ras and Rab interactor 1 0.037 0.110
DAPK2 DAPK2: Death-associated protein kinase 2 0.037 0.109
MYO3A MYO3A: Myosin IIIA 0.037 0.088
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.037 0.088
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.037 0.770
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.037 0.099
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.037 0.275
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.037 0.099
S100A3 S100A3, S100E: Protein S100-A3 0.036 0.049
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.034 0.0727
GHR GHR: Growth hormone receptor precursor 0.034 0.100
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.034 0.081
EPOR EPOR: Erythropoietin receptor precursor 0.034 0.100
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.034 0.064
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.0338 0.042
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0338 0.030
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.034 0.098
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.034 131.00
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.098
PSEN1 PSEN1, AD3, PS1, PSNL1: Presenilin-1 0.034 0.044
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.033 0.127
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.033 0.171
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.032 0.045
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.032 0.859
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.032 0.275
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.032 0.136
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.032 0.874
BMX N/A 0.032 0.775
DYRK3 N/A 0.032 0.097
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.097
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.032 0.251
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.032 0.056
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.032 0.099
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.032 0.275
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.032 0.069
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.032 0.275
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.032 0.046
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.152
TLN2 TLN2: Uncharacterized protein TLN2 0.032 0.078
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.032 0.099
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.032 0.275
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.123
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.032 0.127
CDK7 CDK7, MO15: Cell division protein kinase 7 0.032 0.136
LIMK2 LIMK2: LIM domain kinase 2 0.032 0.152
ROCK1 ROCK1: Rho-associated protein kinase 1 0.032 0.251
WEE1 WEE1: Wee1-like protein kinase 0.032 0.171
CDKL5 N/A 0.032 0.098
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.032 0.275
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.032 0.041
TTN N/A 0.032 0.097
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.032 0.123
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.171
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.032 0.171
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.032 0.114
RASA3 RASA3: Ras GTPase-activating protein 3 0.032 0.136
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.032 0.063
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.032 0.275
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.032 856.00
HSP90AA1 Hsp89-alpha-delta-N 0.032 0.114
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.032 0.191
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.032 0.136
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.032 0.775
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.032 0.139
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.032 0.171
CDK6 CDK6: Cell division protein kinase 6 0.032 0.225
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.032 0.037
ATM ATM: Serine-protein kinase ATM 0.032 0.225
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.032 0.063
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.032 0.136
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.032 0.874
HCK N/A 0.032 1.78
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.032 0.056
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.032 0.038
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.032 0.171
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.032 0.171
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.032 0.029
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.032 0.041
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.032 1.35
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.251
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.110
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.191
TLN1 TLN1: Uncharacterized protein TLN1 0.032 0.225
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.032 1.50
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.032 0.275
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.032 0.094
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.032 0.225
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.032 0.044
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.032 0.041
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.032 0.136
CDK2 CDK2: Cell division protein kinase 2 0.032 0.275
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.032 0.097
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.032 3.64
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.032 0.088
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.032 0.032
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.031 0.073
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.031 0.171
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.031 0.166
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.031 0.166
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.031 0.065
PLD2 PLD2: Phospholipase D2 0.030 0.110
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.030 0.097
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.030 0.123
RDX RDX: Radixin 0.030 0.110
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.029 1.04E3
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.029 0.046
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.029 0.080
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.029 0.110
STK10 STK10: Uncharacterized protein STK10 0.029 0.275
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.029 0.307
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.029 0.152
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.029 0.275
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.029 112.00
FRG1 FRG1: Protein FRG1 0.029 0.063
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.029 0.275
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.029 0.307
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.029 0.416
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.029 0.251
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.029 0.110
JAK1 0.029 1.78
PRKAA1 N/A 0.029 0.152
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.029 0.188
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.029 0.171
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.029 0.225
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.029 0.171
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.032
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.029 0.251
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.029 0.275
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.029 0.098
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.029 0.046
EEF2 EEF2, EF2: Elongation factor 2 0.029 0.046
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.029 0.171
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.461
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.029 2.17
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.029 0.372
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.029 0.139
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.029 0.307
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.029 0.063
STAT6 STAT6: Signal transducer and activator of transcription 6 0.029 370.00
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.029 0.191
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.372
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.029 0.171
CDK5 CDK5: Cell division protein kinase 5 0.029 0.136
RPS6KB1 N/A 0.029 0.372
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.225
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.029 0.225
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 0.275
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.029 1.78
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.029 0.461
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.029 0.109
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.029 0.275
CSK CSK: Tyrosine-protein kinase CSK 0.029 2.17
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.461
PREP PREP, PEP: Prolyl endopeptidase 0.029 0.029
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.275
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.029 0.171
MDN1 MDN1, KIAA0301: Midasin 0.029 0.038
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.044
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.028 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.109
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.028 0.049
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.028 0.109
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.109
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.028 112.00
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.028 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.028 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.028 0.109
TBXA2R TBXA2R: Thromboxane A2 receptor 0.028 0.049
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.028 0.044
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.109
DRD2 DRD2: D(2) dopamine receptor 0.028 0.049
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.028 0.098
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.028 0.049
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.044
FGFR2 N/A 0.028 6.17
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.044
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.028 0.049
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.098
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.028 0.036
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.027 0.195
VIL2 N/A 0.0263 0.171
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.0263 0.056
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.0263 375.00
DES DES: Desmin 0.0263 0.055
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.0263 1.20
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0263 0.171
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.0263 0.088
SYK SYK: Tyrosine-protein kinase SYK 0.0263 2.17
PLD1 PLD1: Phospholipase D1 0.0263 0.110
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.026 0.033
ADCY3 ADCY3, KIAA0511: Adenylate cyclase type 3 0.026 0.073
P2RY4 P2RY4, NRU: P2Y purinoceptor 4 0.026 0.033
ANXA3 ANXA3, ANX3: Annexin A3 0.026 0.065
PSEN2 PSEN2, AD4, PS2, PSNL2, STM2: Presenilin-2 0.025 0.029
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.025 0.091
PPL PPL, KIAA0568: Periplakin 0.025 0.029
0.347
Total Score 4.04