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Evidence of Interaction Between POU2F1 and STAT5A

The interaction score between POU2F1 and STAT5A is 3.02.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between POU2F1 and STAT5A = 0.14

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.30E-3
Orthology N/A N/A
Domains Domains present in POU2F1 and STAT5A:
Domains in POU2F1Domains in STAT5A
IPR001356 Homeobox
IPR000327 POU domain
IPR000972 Octamer-binding transcription factor
IPR012287 Homeodomain-rel.
IPR007103 POU_homeo.
IPR008967 p53-like transcription factor, DNA-binding
IPR000980 SH2 motif
IPR001217 STAT protein
IPR011992 EF-Hand_type.
IPR012345 STAT_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in POU2F1 and STAT5A are listed below.

Domain 1Domain 2Chi Square
IPR012287 Homeodomain-rel. IPR000980 SH2 motif 23.2781
IPR001356 Homeobox IPR000980 SH2 motif 15.6227

The background colour of the table refers to:

  • Blue Domain is only present in POU2F1
  • Yellow Domain is only present in STAT5A
  • Green Domain is present in both POU2F1 and STAT5A

 0.014
Post-translational Modifications

Protein: POU2F1

PTMResidueReference
Phosphorylation 448 PubMed, HPRD
Phosphoserine 448 HPRD

Protein: STAT5A

PTMResidueReference
Dephosphorylation 694 PubMed, HPRD
Phosphorylation 694 PubMed, HPRD
Phosphorylation 726 PubMed, HPRD
Phosphorylation 780 PubMed, HPRD
Phosphotyrosine 694 PubMed, HPRD
Localisation

Protein: POU2F1

LocalisationReference
Nucleus HPRD

Protein: STAT5A

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between POU2F1 and STAT5A that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between POU2F1 andSTAT5A. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , POU2F1 has 971 interactors and STAT5A has 1739 interactors of which there are 565 common interactors.

Common InteractorName of Common InteractorScore for POU2F1-Interactor (?)Score for STAT5A-Interactor (?)
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.307 0.111
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.307 0.111
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.307 0.0818
NBN NBN, NBS, NBS1, P95: Nibrin 0.307 0.091
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.265 0.118
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.251 0.075
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.251 0.040
TGIF2 TGIF2: Homeobox protein TGIF2 0.251 0.036
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.251 0.137
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.251 0.032
CREBBP CREBBP, CBP: CREB-binding protein 0.251 77.30
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.251 0.051
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.251 0.124
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.251 0.091
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.251 0.091
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.251 0.074
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.251 0.0818
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.251 0.111
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.191 0.0818
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.191 0.041
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.191 0.075
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.191 0.111
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.191 0.067
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.191 0.091
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.191 0.032
BRPF1 BRPF1, BR140: Peregrin 0.191 0.139
SP100 N/A 0.191 0.091
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.191 0.041
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.191 0.036
SOX8 SOX8: Transcription factor SOX-8 0.165 0.036
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.165 0.086
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.165 0.044
BRD4 N/A 0.165 0.044
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.165 0.0333
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.165 0.109
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.165 0.049
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.165 0.04
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.155 0.0818
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.155 0.0818
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.152 0.041
MAFG MAFG: Transcription factor MafG 0.152 0.051
LIG4 LIG4: DNA ligase 4 0.152 0.033
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.152 0.033
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.152 0.051
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.152 0.067
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.152 0.090
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.127 0.137
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.127 0.114
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.127 0.124
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.127 0.091
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.127 0.111
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.127 0.051
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.127 0.124
DDX21 DDX21: Nucleolar RNA helicase 2 0.127 0.091
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.127 0.461
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.126 0.054
SOX4 SOX4: Transcription factor SOX-4 0.123 0.090
XRCC1 XRCC1: DNA-repair protein XRCC1 0.123 0.091
FOXL2 FOXL2: Forkhead box protein L2 0.123 0.029
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.123 0.037
MYB MYB: Myb proto-oncogene protein 0.123 0.074
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.123 0.054
VDR VDR, NR1I1: Vitamin D3 receptor 0.123 0.033
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.123 0.027
PGR PGR, NR3C3: Progesterone receptor 0.123 0.0263
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.123 0.046
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.123 0.0263
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.123 0.037
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.123 0.041
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.123 0.041
PPARG CREB3L2-PPARgamma 0.109 0.027
PCAF PCAF: Histone acetyltransferase PCAF 0.109 0.041
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.109 0.032
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.100 0.188
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.110
ELF1 ELF1: ETS-related transcription factor Elf-1 0.096 0.124
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.096 0.153
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.096 0.0818
PLEK PLEK, P47: Pleckstrin 0.096 0.202
IRF3 IRF3: Interferon regulatory factor 3 0.096 0.202
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.096 0.111
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.096 0.0818
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.096 0.032
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.096 0.111
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.096 0.067
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.096 0.111
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.096 0.029
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.096 0.051
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.096 0.0818
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.096 0.148
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.096 0.0818
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.096 0.246
LIMD1 LIMD1: LIM domain-containing protein 1 0.096 0.051
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.096 0.111
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.096 0.0818
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.096 0.0818
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.083 0.044
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.083 0.044
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.083
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.049
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.083 0.044
CREB1 CREB1: cAMP response element-binding protein 0.083 0.044
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.083 0.049
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.083 0.044
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.083 0.044
HES6 HES6: Transcription cofactor HES-6 0.083 0.049
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.083 0.049
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.083 0.036
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.083 0.044
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.081 0.123
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.081 0.171
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.080 0.275
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.077 0.041
ETS1 ETS1, EWSR2: Protein C-ets-1 0.077 0.051
H1FX H1FX: Histone H1x 0.077 0.124
JUN JUN: Transcription factor AP-1 0.077 0.051
JUND JUND: Transcription factor jun-D 0.077 0.0818
RFX1 RFX1: MHC class II regulatory factor RFX1 0.077 0.029
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.077 0.091
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.077 0.0818
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.077 0.0818
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.077 0.0818
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.077 0.041
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.077 0.372
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.077 0.051
JUNB JUNB: Transcription factor jun-B 0.077 0.0818
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.077 0.274
MYF5 MYF5: Myogenic factor 5 0.077 0.041
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.077 0.051
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.077 0.051
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.077 0.0818
HD HD, IT15: Huntingtin 0.074 0.052
GTF2F2 N/A 0.062 0.057
ETS2 ETS2: Protein C-ets-2 0.062 0.126
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.062 0.067
ELK1 ELK1: ETS domain-containing protein Elk-1 0.062 0.029
ERG ERG: Transcriptional regulator ERG 0.062 0.124
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.062 0.064
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.062 0.029
BACH1 BACH1: Transcription regulator protein BACH1 0.062 0.075
VIM VIM: Vimentin 0.062 0.057
SAT SAT1, SAT: Diamine acetyltransferase 1 0.062 0.026
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.062 0.251
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.062 0.086
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.062 0.041
ERF ERF: ETS domain-containing transcription factor ERF 0.062 0.0453
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.062 0.075
ETV1 ETV1, ER81: ETS translocation variant 1 0.062 0.033
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.061 0.171
MYH9 MYH9: Myosin-9 0.060 0.181
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.060 0.251
ROCK1 ROCK1: Rho-associated protein kinase 1 0.060 0.251
RPS10 RPS10: 40S ribosomal protein S10 0.057 0.063
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.057 0.038
THOC1 THOC1, HPR1: THO complex subunit 1 0.057 0.188
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.057 0.046
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.057 0.155
LPXN LPXN, LDLP: Leupaxin 0.057 0.139
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.057 0.0425
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.057 0.029
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.055 0.029
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.055 0.041
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.055 0.033
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.055 0.051
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.055 0.065
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.055 0.081
HES1 HES1, HL, HRY: Transcription factor HES-1 0.055 0.026
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.052 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.052 0.044
PPEF1 N/A 0.052 0.165
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.052 0.036
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.052 0.032
FNBP1 N/A 0.052 0.372
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.052 0.246
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.052 0.046
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.052 0.046
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.052 0.307
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.052
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.049 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.049 0.028
CASP14 CASP14: Caspase-14 precursor 0.049 0.028
LMO6 LMO6: LIM domain only protein 6 0.049 0.075
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.049 0.083
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.049 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.049 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.049 0.028
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.048 0.246
CCNB1 Cyclin B1 0.048 0.051
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.046 0.136
VAV1 VAV1, VAV: Proto-oncogene vav 0.046 0.372
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.046 0.461
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.0453 0.171
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0453 0.146
YWHAQ YWHAQ: 14-3-3 protein theta 0.0453 0.032
LIMS1 N/A 0.0453 0.210
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.0453 0.032
LPP LPP: Lipoma-preferred partner 0.0453 0.049
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.0453 0.052
CASP3 CASP3, CPP32: Caspase-3 precursor 0.0453 0.046
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.0425 0.032
ABCF1 N/A 0.0425 0.052
YY1 YY1: Transcriptional repressor protein YY1 0.0425 0.090
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.0425 0.032
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.0425 0.032
GSK3B N/A 0.0425 0.038
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.0425 0.063
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.0425 0.032
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.0425 0.032
KIAA1012 KIAA1012: Protein TRS85 homolog 0.0425 0.046
NCOA3 N/A 0.0425 0.027
TIAL1 TIAL1: Nucleolysin TIAR 0.0425 0.040
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.0425 0.471
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.0425 0.032
UBAP2 N/A 0.0425 0.0425
NUP153 N/A 0.0425 0.032
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.0425 0.372
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0425 0.046
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.0425 0.032
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.0425 0.0446
MDN1 MDN1, KIAA0301: Midasin 0.0425 0.038
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.0425 0.275
POLA2 POLA2: DNA polymerase subunit alpha B 0.0425 0.032
MATR3 MATR3, KIAA0723: Matrin-3 0.0425 0.074
ARFGAP1 N/A 0.0425 0.101
TP53 TP53, P53: Cellular tumor antigen p53 0.0425 0.067
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.0425 0.067
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.0425 0.032
SOS1 SOS1: Son of sevenless homolog 1 0.0425 0.148
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.0425 0.461
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.0425 0.027
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.0425 0.307
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.0425 0.074
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.0425 0.090
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.0425 0.032
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.0425 0.040
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.0425 0.063
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.0425 0.040
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.0425 0.126
RPS6KB1 N/A 0.0425 0.372
TCOF1 N/A 0.0425 0.027
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.0425 0.027
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.0425 0.027
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.0425 0.040
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.0425 0.040
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.0425 0.275
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.0425 0.040
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.0425 0.136
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.0425 0.111
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.0425 0.090
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.0425 0.191
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.0425 0.061
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.0425 0.046
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.0425 0.032
PTMA N/A 0.0425 0.0446
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.0425 0.171
RBM14 RBM14, SIP: RNA-binding protein 14 0.0425 0.036
MCM3 MCM3: DNA replication licensing factor MCM3 0.0425 0.090
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.0425 66.00
NOL1 N/A 0.0425 0.032
IFI16 N/A 0.0425 0.027
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.0425 0.155
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.0425 0.046
WBSCR20A N/A 0.0425 0.032
EP300 N/A 0.0425 0.032
MYO18A 0.04 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.04 0.075
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.04 0.075
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.04 0.148
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.039 0.110
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.039 0.088
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.037 0.136
GMIP GMIP: GEM-interacting protein 0.037 0.139
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.037 0.225
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.037 0.088
FHL1 FHL1, SLIM1: Four and a half LIM domains protein 1 0.037 0.049
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.037 0.123
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.037 0.110
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.037 0.077
PRPH PRPH, NEF4, PRPH1: Peripherin 0.037 0.044
MYO3A MYO3A: Myosin IIIA 0.034 0.088
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.034 47.50
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.034 0.097
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.034 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.034 0.044
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.034 0.034
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.034 0.098
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.034 0.049
SAFB2 SAFB2, KIAA0138: Scaffold attachment factor B2 0.033 0.049
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.032 0.056
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.032 0.063
LIMA1 LIMA1, EPLIN, PP624, SREBP3: LIM domain and actin-binding protein 1 0.032 0.044
DES DES: Desmin 0.032 0.055
LIMK2 LIMK2: LIM domain kinase 2 0.032 0.152
ZYX ZYX: Zyxin 0.032 0.096
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.032 0.071
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.032 0.032
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.032 0.0446
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.032 0.036
MARK2 N/A 0.032 0.0425
LIG1 LIG1: DNA ligase 1 0.032 0.032
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.032 0.040
PRKAA1 N/A 0.032 0.152
ZNF335 ZNF335: Zinc finger protein 335 0.032 0.041
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.032 0.275
CDK7 CDK7, MO15: Cell division protein kinase 7 0.032 0.136
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.032 0.139
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.032 0.090
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.032 0.036
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.032 0.225
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.032 0.109
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.032 0.090
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.032 0.032
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.032 0.114
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.032 0.067
ZNF267 ZNF267: Zinc finger protein 267 0.032 0.061
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.032 0.032
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.032 0.275
COPA COPA: Coatomer subunit alpha 0.032 0.038
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.032 0.054
PHF10 N/A 0.032 0.040
NFATC1 N/A 0.032 0.075
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.171
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.032 0.036
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.032 0.040
KIF11 N/A 0.032 0.032
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.032 0.032
MTF1 MTF1: Metal regulatory transcription factor 1 0.032 0.067
SAPS3 N/A 0.032 0.046
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.032 0.070
STAT2 STAT2: Signal transducer and activator of transcription 2 0.032 0.126
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.032 0.0425
SET SET: Protein SET 0.032 0.036
TOP2B N/A 0.032 0.036
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.032 0.032
PPP1R8 N/A 0.032 0.040
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.032 0.052
CHUK N/A 0.032 0.052
ESPL1 N/A 0.032 0.0425
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.032 0.859
HDAC3 HDAC3: Histone deacetylase 3 0.032 0.111
TRRAP N/A 0.032 0.052
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.032 0.275
KLHDC4 N/A 0.032 0.038
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.032 0.032
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.032 0.036
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.032 0.461
SYMPK SYMPK, SPK: Symplekin 0.032 0.029
RB1 RB1: Retinoblastoma-associated protein 0.032 0.091
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.032 0.275
CBX3 CBX3: Chromobox protein homolog 3 0.032 0.032
CDK2 CDK2: Cell division protein kinase 2 0.032 0.275
WEE1 WEE1: Wee1-like protein kinase 0.032 0.171
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.032 0.188
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.032 0.304
AIP AIP, XAP2: AH receptor-interacting protein 0.032 0.114
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.032 0.088
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.032 0.152
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.032 0.027
UNG N/A 0.032 0.032
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.032 0.171
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.032 0.139
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.032 0.054
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.032 0.038
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.032 0.275
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.032 0.416
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.032 409.00
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.032 0.070
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.032 0.110
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.032 0.275
DNMT1 DNMT1, AIM, DNMT: DNA 0.032 0.027
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.307
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.032 0.090
COPE COPE: Coatomer subunit epsilon 0.032 0.038
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.032 0.275
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.032 0.078
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.032 0.032
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.032 0.036
GNB2L1 Lung cancer oncogene 7 0.032 0.036
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.032 0.372
CXorf9 N/A 0.032 0.275
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.032 0.067
RELA RELA, NFKB3: Transcription factor p65 0.032 0.067
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.032 0.041
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.032 0.091
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.032 0.251
CDK4 CDK4: Cell division protein kinase 4 0.032 0.275
API5 N/A 0.032 0.0425
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.032 0.032
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.032 0.067
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.032 0.171
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.032 0.063
CCNH CCNH: Cyclin-H 0.032 0.041
FADD FADD, MORT1: Protein FADD 0.031 0.075
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.031 0.026
TNKS2 TNKS2, PARP5B, TANK2, TNKL: Tankyrase-2 0.0308 0.047
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.030 0.171
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.030 0.225
GFAP GFAP: Glial fibrillary acidic protein 0.029 0.049
CRIP2 CRIP2, CRP2: Cysteine-rich protein 2 0.029 0.049
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.029 0.056
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.165
DSP DSP: Desmoplakin 0.028 0.049
CDC25C CDC25C: M-phase inducer phosphatase 3 0.028 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.028 0.148
HDAC8 N/A 0.028 0.049
RBL1 RBL1: Retinoblastoma-like protein 1 0.028 0.044
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.165
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.028 0.025
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.04
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.028 0.098
ADK ADK: Adenosine kinase 0.028 0.025
CAMKK1 N/A 0.028 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.028 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.028 0.098
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.028 0.148
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.04
GIT2 N/A 0.028 0.075
MAP2K3 N/A 0.028 12.00
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.028 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.028 0.148
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.028 0.047
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.148
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.028 0.025
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.028 0.036
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.04
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.028 0.049
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.148
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.165
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.028 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.028 0.148
PRKCB1 N/A 0.028 0.025
CAMK2A N/A 0.028 0.025
ELMO1 N/A 0.028 0.148
CETN1 CETN1, CEN1, CETN: Centrin-1 0.028 0.036
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.028 0.030
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.028 0.098
NF2 NF2, SCH: Merlin 0.028 0.165
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.028 0.148
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.165
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.028 0.036
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.028 131.00
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.028 0.165
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.028 0.036
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.028 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.028 0.148
BCOR N/A 0.028 0.025
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.04
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.028 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.028 0.148
CCNT2 CCNT2: Cyclin-T2 0.028 0.044
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.028 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.028 0.148
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.028 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.028 0.148
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
MAPKAPK5 N/A 0.028 0.165
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.04
HDAC7A N/A 0.028 0.044
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.028 0.025
GRK6 N/A 0.028 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.028 0.148
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.028 0.148
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.165
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.028 0.098
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.028 0.075
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.028 0.098
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.028 0.044
MAPK15 N/A 0.028 0.165
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.028 0.148
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.028 0.025
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.028 0.049
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.028 0.148
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.028 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.028 0.036
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.165
EEF2K EEF2K: Elongation factor 2 kinase 0.028 0.148
NIPBL N/A 0.028 0.025
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.165
PHLDB2 N/A 0.028 0.028
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.028 0.098
GATA5 GATA5: Transcription factor GATA-5 0.027 0.356
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.0263 0.099
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.0263 0.099
SH3BP3 0.026 0.037
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.026 0.0425
SNRK SNRK, KIAA0096, SNFRK: SNF-related serine/threonine-protein kinase 0.026 0.029
HDAC6 HDAC6, JM21: Histone deacetylase 6 0.026 0.041
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.026 0.251
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.026 0.032
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.026 0.029
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.026 0.046
HDAC2 HDAC2: Histone deacetylase 2 0.026 0.0818
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.026 0.148
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.026 0.032
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.026 0.037
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.026 0.152
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.026 0.111
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.026 0.123
HDAC5 HDAC5, KIAA0600: Histone deacetylase 5 0.026 0.026
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.026 0.036
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.026 0.032
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.026 0.032
ZFX ZFX: Zinc finger X-chromosomal protein 0.026 0.046
PCNA PCNA: Proliferating cell nuclear antigen 0.026 0.032
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.026 0.136
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.026 0.049
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.026 0.054
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.026 0.275
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.026 0.171
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.026 0.191
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.0425
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.026 0.054
IRS2 IRS2: Insulin receptor substrate 2 0.026 0.191
STK10 STK10: Uncharacterized protein STK10 0.026 0.275
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.026 0.225
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.026 0.171
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.026 0.070
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.026 0.099
GRLF1 N/A 0.026 0.055
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.026 0.275
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.026 0.067
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.026 0.038
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.026 0.038
KIAA0853 N/A 0.026 0.027
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.026 0.191
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.026 0.109
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.026 0.136
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.026 0.0818
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.026 0.038
RUNX1 N/A 0.026 0.040
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.026 0.027
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.026 0.069
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.026 0.097
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.026 0.123
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.026 0.171
DIAPH1 Diaphanous 1 0.026 0.063
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.026 0.067
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.048
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.026 0.0818
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.026 0.027
HIVEP1 N/A 0.026 0.061
SP3 SP3: Transcription factor Sp3 0.026 0.090
WDR1 N/A 0.026 0.027
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.026 0.051
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.026 0.225
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.026 0.225
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.026 0.090
CDK5 CDK5: Cell division protein kinase 5 0.026 0.136
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.026 0.067
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.026 0.251
ATM ATM: Serine-protein kinase ATM 0.026 0.225
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.026 0.038
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.026 0.275
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.026 0.275
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.026 0.225
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.026 0.225
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.025 0.032
0.572
Total Score 3.02