Home
Advanced Search
Help
Update History
Statistics
Downloads
The Barton Group
<<< Back to POU2F1

Evidence of Interaction Between POU2F1 and SMAD2

The interaction score between POU2F1 and SMAD2 is 17.60.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between POU2F1 and SMAD2 = 0.36

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 3.80E-3
Orthology N/A N/A
Domains Domains present in POU2F1 and SMAD2:
Domains in POU2F1Domains in SMAD2
IPR001356 Homeobox
IPR000327 POU domain
IPR000972 Octamer-binding transcription factor
IPR012287 Homeodomain-rel.
IPR007103 POU_homeo.
IPR003619 Dwarfin protein, domain A
IPR001132 Dwarfin protein
IPR013019 MAD_MH1.

The Chi square scores for co-occurrence of domains that are present in POU2F1 and SMAD2 are listed below.

Domain 1Domain 2Chi Square
IPR001356 Homeobox IPR001132 Dwarfin protein 27.1975
IPR001356 Homeobox IPR013019 MAD_MH1. 27.1975
IPR001356 Homeobox IPR003619 Dwarfin protein, domain A 26.8663
IPR012287 Homeodomain-rel. IPR001132 Dwarfin protein 16.2426
IPR012287 Homeodomain-rel. IPR013019 MAD_MH1. 16.2426
IPR012287 Homeodomain-rel. IPR003619 Dwarfin protein, domain A 16.0052

The background colour of the table refers to:

  • Blue Domain is only present in POU2F1
  • Yellow Domain is only present in SMAD2
  • Green Domain is present in both POU2F1 and SMAD2

 0.083
Post-translational Modifications

Protein: POU2F1

PTMResidueReference
Phosphorylation 448 PubMed, HPRD
Phosphoserine 448 HPRD

Protein: SMAD2

PTMResidueReference
Phosphorylation 8 PubMed, HPRD
Phosphorylation 110 PubMed, HPRD
Phosphorylation 220 PubMed, HPRD
Phosphorylation 240 PubMed, HPRD
Phosphorylation 245 PubMed, HPRD
Phosphorylation 250 PubMed, HPRD
Phosphorylation 260 PubMed, HPRD
Phosphorylation 464 PubMed, HPRD
Phosphorylation 465 PubMed, HPRD
Phosphorylation 467 PubMed, HPRD
Phosphoserine 240 PubMed, HPRD
Phosphoserine 465 HPRD
Phosphoserine 467 HPRD
Phosphothreonine 8 PubMed, HPRD
Localisation

Protein: POU2F1

LocalisationReference
Nucleus HPRD

Protein: SMAD2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between POU2F1 and SMAD2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between POU2F1 andSMAD2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , POU2F1 has 971 interactors and SMAD2 has 1164 interactors of which there are 728 common interactors.

Common InteractorName of Common InteractorScore for POU2F1-Interactor (?)Score for SMAD2-Interactor (?)
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.307 0.385
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.307 0.063
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.307 0.146
NBN NBN, NBS, NBS1, P95: Nibrin 0.307 0.917
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.265 0.426
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.251 0.144
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.251 0.129
TGIF2 TGIF2: Homeobox protein TGIF2 0.251 0.260
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.251 0.129
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.251 0.063
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.251 0.155
CREBBP CREBBP, CBP: CREB-binding protein 0.251 90.40
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.251 0.071
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.251 0.132
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.251 0.132
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.251 0.052
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.251 0.260
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.251 0.385
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.251 0.233
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.251 0.241
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.191 0.087
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.191 0.225
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.191 0.251
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.191 0.188
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.191 0.114
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.191 0.0971
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.191 0.155
MECP2 MECP2: Methyl-CpG-binding protein 2 0.191 0.0425
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.191 0.129
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.191 0.086
BRPF1 BRPF1, BR140: Peregrin 0.191 0.114
SP100 N/A 0.191 0.260
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.191 0.086
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.191 0.144
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.191 0.210
SOX8 SOX8: Transcription factor SOX-8 0.165 0.075
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.165 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.165 0.075
BRD4 N/A 0.165 0.047
DIDO1 N/A 0.165 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.165 0.025
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.165 0.028
DLX3 DLX3: Homeobox protein DLX-3 0.165 0.075
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.165 0.028
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.165 0.165
CUTL1 CUTL1: Homeobox protein cut-like 1 0.165 0.083
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.165 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.165 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.165 0.075
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.165 0.083
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.165 0.083
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.155 0.129
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.155 0.129
SRF SRF: Serum response factor 0.152 0.233
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.152 0.139
MAFG MAFG: Transcription factor MafG 0.152 0.114
MYBL2 MYBL2, BMYB: Myb-related protein B 0.152 0.114
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.152 41.40
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.152 0.049
CDX2 CDX2, CDX3: Homeobox protein CDX-2 0.152 0.049
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.152 0.046
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.152 0.188
SATB1 SATB1: DNA-binding protein SATB1 0.152 0.114
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.127 0.129
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.127 0.233
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.127 0.144
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.127 0.430
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.127 0.129
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.127 0.063
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.127 0.430
DDX21 DDX21: Nucleolar RNA helicase 2 0.127 0.144
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.127 0.385
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.126 0.032
SOX4 SOX4: Transcription factor SOX-4 0.123 0.086
XRCC1 XRCC1: DNA-repair protein XRCC1 0.123 0.070
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.123 0.044
FOXL2 FOXL2: Forkhead box protein L2 0.123 0.097
MYB MYB: Myb proto-oncogene protein 0.123 0.077
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.123 0.086
VDR VDR, NR1I1: Vitamin D3 receptor 0.123 0.086
EN2 EN2: Homeobox protein engrailed-2 0.123 0.044
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.123 0.032
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.123 0.055
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.123 0.127
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.123 0.056
MLLT7 N/A 0.123 0.110
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.123 0.136
SOX11 SOX11: Transcription factor SOX-11 0.109 0.049
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.109 0.049
PCAF PCAF: Histone acetyltransferase PCAF 0.109 0.086
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.109 0.034
NKX2-5 NKX2-5, CSX, NKX2.5, NKX2E: Homeobox protein Nkx-2.5 0.109 0.044
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.100 0.041
HOXB6 HOXB6, HOX2B: Homeobox protein Hox-B6 0.098 0.044
MTA1 MTA1: Metastasis-associated protein MTA1 0.096 0.063
ELF1 ELF1: ETS-related transcription factor Elf-1 0.096 0.430
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.096 0.139
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.096 0.144
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.096 66.70
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.096 0.139
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.096 0.063
MEF2A N/A 0.096 0.155
PLEK PLEK, P47: Pleckstrin 0.096 0.144
IRF3 IRF3: Interferon regulatory factor 3 0.096 0.260
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.096 0.129
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.096 0.046
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.096 0.078
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.096 0.129
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.096 0.139
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.096 0.078
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.096 0.056
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.096 0.139
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.096 0.385
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.096 0.146
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.096 0.233
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.096 0.188
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.096 0.188
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.096 0.038
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.096 0.063
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.096 0.078
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.083 0.025
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.083 0.075
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.083 0.025
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.083 0.083
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.083
RNF20 0.083 0.025
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.083
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.083 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.083 0.025
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.083 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.083 0.025
MAX MAX: Protein max 0.083 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.083 0.025
CREB1 CREB1: cAMP response element-binding protein 0.083 0.075
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.083 0.083
C20orf18 N/A 0.083 0.052
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.083 0.028
UHRF1 0.083 0.052
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.083 35.90
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.083 0.025
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.083 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.083 0.075
TFAP4 TFAP4: Transcription factor AP-4 0.083 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.083 0.075
HES6 HES6: Transcription cofactor HES-6 0.083 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.083 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.083 0.028
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.083 0.075
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.083 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.083 0.025
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.083 0.028
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.081 0.057
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.080 0.078
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.077 0.086
ETS1 ETS1, EWSR2: Protein C-ets-1 0.077 0.139
H1FX H1FX: Histone H1x 0.077 0.155
JUN JUN: Transcription factor AP-1 0.077 0.114
JUND JUND: Transcription factor jun-D 0.077 0.188
RFX1 RFX1: MHC class II regulatory factor RFX1 0.077 0.049
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.077 0.096
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.077 0.086
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.077 0.086
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.077 0.029
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.077 0.056
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.077 0.078
ID2 ID2: DNA-binding protein inhibitor ID-2 0.077 0.087
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.077 0.139
JUNB JUNB: Transcription factor jun-B 0.077 0.188
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.077 0.210
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.077 0.139
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.077 0.063
HD HD, IT15: Huntingtin 0.074 0.0446
GTF2F2 N/A 0.062 0.127
ETS2 ETS2: Protein C-ets-2 0.062 0.096
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.062 0.114
ELK1 ELK1: ETS domain-containing protein Elk-1 0.062 0.049
ERG ERG: Transcriptional regulator ERG 0.062 0.077
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.062 0.035
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.062 0.062
AHR AHR: Aryl hydrocarbon receptor precursor 0.062 0.038
BACH1 BACH1: Transcription regulator protein BACH1 0.062 0.155
MEF2C MEF2C: Myocyte-specific enhancer factor 2C 0.062 0.069
VIM VIM: Vimentin 0.062 0.0425
SAT SAT1, SAT: Diamine acetyltransferase 1 0.062 0.155
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.062 0.052
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.062 0.029
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.026
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.062 0.139
ERF ERF: ETS domain-containing transcription factor ERF 0.062 0.127
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.062 0.026
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.062 0.063
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.062 0.032
ETV1 ETV1, ER81: ETS translocation variant 1 0.062 0.056
MYH9 MYH9: Myosin-9 0.060 0.063
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.060 0.0425
ROCK1 ROCK1: Rho-associated protein kinase 1 0.060 0.087
RPS10 RPS10: 40S ribosomal protein S10 0.057 0.040
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.057 0.040
THOC1 THOC1, HPR1: THO complex subunit 1 0.057 0.032
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.057 0.040
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.057 0.0446
LPXN LPXN, LDLP: Leupaxin 0.057 0.066
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.057 0.027
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.057 0.032
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.055 0.056
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.055 0.069
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.055 0.086
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.055 0.114
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.055 0.062
NFIB N/A 0.055 0.031
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.055 0.077
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.055 0.062
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.052 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.052 0.025
PPEF1 N/A 0.052 0.028
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.052 0.075
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.052 0.129
FNBP1 N/A 0.052 0.276
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.052 0.129
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.052 0.078
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.052 0.233
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.052 0.144
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.144
CIC CIC, KIAA0306: Protein capicua homolog 0.051 0.031
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.048 0.233
CCNB1 Cyclin B1 0.048 0.038
VAV1 VAV1, VAV: Proto-oncogene vav 0.046 0.137
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.046 0.040
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.0453 0.137
YWHAQ YWHAQ: 14-3-3 protein theta 0.0453 0.036
LIMS1 N/A 0.0453 0.036
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.0453 0.027
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.0453 0.0446
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.0425 0.129
ABCF1 N/A 0.0425 0.144
SMARCC2 N/A 0.0425 0.052
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.0425 0.063
YY1 YY1: Transcriptional repressor protein YY1 0.0425 0.822
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.0425 0.276
SREBF2 N/A 0.0425 0.070
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.0425 0.129
GSK3B N/A 0.0425 0.078
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.0425 0.129
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.0425 0.129
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.0425 0.129
KIAA1012 KIAA1012: Protein TRS85 homolog 0.0425 0.129
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.0425 18.30
NCOA3 N/A 0.0425 0.144
TIAL1 TIAL1: Nucleolysin TIAR 0.0425 0.129
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.0425 0.276
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.0425 0.078
UBAP2 N/A 0.0425 0.052
NUP153 N/A 0.0425 0.129
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.0425 0.129
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0425 0.385
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.0425 0.276
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.0425 0.144
MDN1 MDN1, KIAA0301: Midasin 0.0425 0.063
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.0425 0.078
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.0425 0.129
GTF3C1 N/A 0.0425 0.070
POLA2 POLA2: DNA polymerase subunit alpha B 0.0425 0.078
MATR3 MATR3, KIAA0723: Matrin-3 0.0425 0.430
ARFGAP1 N/A 0.0425 0.070
TP53 TP53, P53: Cellular tumor antigen p53 0.0425 0.146
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.0425 0.233
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.0425 0.129
SOS1 SOS1: Son of sevenless homolog 1 0.0425 0.118
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.0425 0.129
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.0425 0.087
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.0425 0.144
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.0425 0.063
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.0425 0.430
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.0425 0.385
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.0425 0.276
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.0425 0.129
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.0425 0.129
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.0425 0.129
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.0425 0.063
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.0425 0.063
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.0425 0.052
RPS6KB1 N/A 0.0425 0.129
TCOF1 N/A 0.0425 0.087
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.0425 0.188
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.0425 0.087
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.0425 0.063
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.0425 0.087
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.0425 0.038
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.0425 0.129
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.0425 0.129
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.0425 0.063
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.0425 0.078
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.0425 0.071
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.0425 0.129
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.0425 0.385
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.0425 0.070
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.0425 0.430
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.0425 0.129
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.0425 0.078
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.0425 0.046
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.0425 0.078
PTMA N/A 0.0425 0.144
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.0425 0.046
RBM14 RBM14, SIP: RNA-binding protein 14 0.0425 0.144
MCM3 MCM3: DNA replication licensing factor MCM3 0.0425 0.078
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.0425 0.078
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.0425 0.276
NOL1 N/A 0.0425 0.078
IFI16 N/A 0.0425 0.308
AFF1 N/A 0.0425 0.070
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.0425 0.087
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.0425 0.129
WBSCR20A N/A 0.0425 0.078
EP300 N/A 0.0425 0.078
ADNP ADNP, ADNP1, KIAA0784: Activity-dependent neuroprotector 0.041 0.0255
TFAM TFAM, TCF6L2: Transcription factor A, mitochondrial precursor 0.041 0.038
BBX N/A 0.041 0.0255
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.04 0.044
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.037 0.067
GMIP GMIP: GEM-interacting protein 0.037 0.032
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.037 0.227
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.037 0.054
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.037 0.057
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.034 0.034
SAFB2 SAFB2, KIAA0138: Scaffold attachment factor B2 0.033 0.101
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.032 0.129
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.032 0.063
SEC31L1 N/A 0.032 0.233
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.0425
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.032 0.078
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.032 0.070
RBM7 0.032 0.063
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.032 0.087
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.032 0.070
MARK2 N/A 0.032 0.070
LIG1 LIG1: DNA ligase 1 0.032 0.046
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.032 0.109
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.032 0.063
CUL4B N/A 0.032 0.078
PRKAA1 N/A 0.032 0.032
TOP3A TOP3A, TOP3: DNA topoisomerase 3-alpha 0.032 0.029
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.032 0.129
ZNF335 ZNF335: Zinc finger protein 335 0.032 0.188
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.032 0.063
CDK7 CDK7, MO15: Cell division protein kinase 7 0.032 0.063
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.032 0.129
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.032 0.038
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.032 0.078
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.032 0.070
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.032 0.063
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.032 0.026
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.032 0.078
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.032 0.063
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.032 0.078
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.032 0.046
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.032 0.063
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.032 0.114
ZNF267 ZNF267: Zinc finger protein 267 0.032 0.260
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.032 0.078
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.032 0.046
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.032 0.046
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.032 0.078
COPA COPA: Coatomer subunit alpha 0.032 0.233
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.032 0.078
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.032 0.233
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.032 0.038
PHF10 N/A 0.032 0.063
NFATC1 N/A 0.032 0.052
H2AFX H2AFX, H2AX: Histone H2A.x 0.032 0.046
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.078
SSB SSB: Lupus La protein 0.032 0.078
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.032 0.087
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.032 0.078
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.032 0.233
KIF11 N/A 0.032 0.046
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.032 0.129
MTF1 MTF1: Metal regulatory transcription factor 1 0.032 90.40
CENPA CENPA: Histone H3-like centromeric protein A 0.032 0.052
SAPS3 N/A 0.032 0.063
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.032 0.144
STAT2 STAT2: Signal transducer and activator of transcription 2 0.032 0.0425
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.032 0.070
RBM6 RBM6, DEF3: RNA-binding protein 6 0.032 0.052
SET SET: Protein SET 0.032 0.087
TOP2B N/A 0.032 0.087
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.032 0.188
PPP1R8 N/A 0.032 0.385
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.032 0.087
POLR2A POLR2A: Uncharacterized protein POLR2A 0.032 0.038
CHUK N/A 0.032 0.087
ESPL1 N/A 0.032 0.0425
COIL COIL, CLN80: Coilin 0.032 0.0425
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.032 0.032
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.032 0.078
HDAC3 HDAC3: Histone deacetylase 3 0.032 0.129
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.032 0.046
TRRAP N/A 0.032 0.052
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.032 0.078
KLHDC4 N/A 0.032 0.078
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.032 0.129
NPM1 NPM1, NPM: Nucleophosmin 0.032 0.063
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.032 0.129
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.032 0.144
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.032 0.276
SYMPK SYMPK, SPK: Symplekin 0.032 0.046
RB1 RB1: Retinoblastoma-associated protein 0.032 0.132
CDC20 CDC20: Cell division cycle protein 20 homolog 0.032 0.114
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.032 0.063
CBX3 CBX3: Chromobox protein homolog 3 0.032 0.129
CDK2 CDK2: Cell division protein kinase 2 0.032 0.046
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.032 0.086
WEE1 WEE1: Wee1-like protein kinase 0.032 0.038
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.032 0.129
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.032 0.241
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.032 0.046
AIP AIP, XAP2: AH receptor-interacting protein 0.032 0.046
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.032 0.069
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.032 0.129
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.032 0.0425
CUL5 CUL5, VACM1: Cullin-5 0.032 0.078
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.032 0.087
UNG N/A 0.032 0.063
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.032 0.046
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.032 0.063
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.032 0.046
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.032 0.129
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.032 0.063
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.032 0.038
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.032 0.163
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.032 0.063
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.032 0.046
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.032 0.038
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.032 0.087
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.032 0.063
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.032 0.029
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.032 0.078
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.032 0.078
DNMT1 DNMT1, AIM, DNMT: DNA 0.032 0.070
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.144
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.032 0.046
COPE COPE: Coatomer subunit epsilon 0.032 0.063
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.032 0.078
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.032 0.129
CRSP2 MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol 0.032 0.038
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.032 0.129
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.032 0.144
GNB2L1 Lung cancer oncogene 7 0.032 0.260
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.032 0.129
CXorf9 N/A 0.032 0.385
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.032 0.129
RELA RELA, NFKB3: Transcription factor p65 0.032 0.046
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.032 0.139
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.032 0.052
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.032 0.087
CDK4 CDK4: Cell division protein kinase 4 0.032 0.063
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.032 0.139
API5 N/A 0.032 0.087
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.032 0.129
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.032 0.188
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.032 0.046
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.032 0.063
CCNH CCNH: Cyclin-H 0.032 0.046
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.032 0.063
PHF20 PHF20, C20orf104, GLEA2, HCA58, NZF, TZP: PHD finger protein 20 0.032 0.027
TNKS2 TNKS2, PARP5B, TANK2, TNKL: Tankyrase-2 0.0308 0.038
SP140 SP140, LYSP100: Nuclear body protein SP140 0.0308 0.050
FOXP1 FOXP1, HSPC215: Forkhead box protein P1 0.0308 0.028
SMARCE1 SMARCE1, BAF57: SWI/SNF-related matrix-associated actin-dependent regulator of c 0.0308 0.038
HOXA7 HOXA7, HOX1A: Homeobox protein Hox-A7 0.0308 5.36
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
EDF1 EDF1: Endothelial differentiation-related factor 1 0.028 0.025
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.028
IWS1 IWS1, IWS1L: IWS1 homolog 0.028 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.028 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.028 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.028 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.028 0.025
HDAC8 N/A 0.028 0.028
RBL1 RBL1: Retinoblastoma-like protein 1 0.028 0.047
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.028
RAB4A N/A 0.028 0.165
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.028 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.028 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.028 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.028 0.025
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.083
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.028 0.025
ADK ADK: Adenosine kinase 0.028 0.025
CAMKK1 N/A 0.028 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.028 0.075
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.028 0.025
SYTL4 Endocrine transmitter regulatory protein 0.028 0.083
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.028 0.075
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.028 0.025
IRF7 N/A 0.028 0.028
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.028 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.028 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.028 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.028 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.028 0.025
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.083
GIT2 N/A 0.028 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.028 0.025
MAPK8IP3 N/A 0.028 0.025
MAP2K3 N/A 0.028 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.028 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.028 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.028 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.028 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.028 0.025
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.028 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.028 0.148
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.028 0.075
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.028 0.025
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.083
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.028 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.028 0.025
KIF1B N/A 0.028 0.028
SNRPB N/A 0.028 0.028
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.028 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.028 0.025
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
DUSP15 N/A 0.028 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.028 0.047
SON 0.028 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.028 0.025
PRKCB1 N/A 0.028 0.025
SEC13L1 N/A 0.028 0.025
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.083
CAMK2A N/A 0.028 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.028 0.075
BID BID: BH3-interacting domain death agonist 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ELMO1 N/A 0.028 0.025
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.028 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.028 0.025
TCEA1 N/A 0.028 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.028 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.028 0.075
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.028 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.028 0.025
NF2 NF2, SCH: Merlin 0.028 0.028
WDR54 N/A 0.028 0.083
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.028 0.025
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
ATXN2L N/A 0.028 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.028 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.028 0.025
HTATIP N/A 0.028 0.025
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.028 0.075
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.028 0.025
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
NES N/A 0.028 0.028
KCTD1 0.028 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.028 0.025
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.028 0.083
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.028 0.075
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.028 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.028 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.028 0.025
BCOR N/A 0.028 0.025
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.083
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.028 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.028 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.028 0.075
CCNT2 CCNT2: Cyclin-T2 0.028 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.028 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.028 0.025
CORO6 N/A 0.028 0.028
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.028 0.047
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
ZNF265 N/A 0.028 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.028 0.025
C20orf77 N/A 0.028 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.028 0.025
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.165
MAPKAPK5 N/A 0.028 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.083
HDAC7A N/A 0.028 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.028 0.025
GRK6 N/A 0.028 0.025
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.028 0.025
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
C13orf8 N/A 0.028 0.028
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.028 0.075
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.028 0.025
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
FLJ23436 N/A 0.028 0.025
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.028 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.028 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.028 0.025
NUP98 N/A 0.028 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.028 0.025
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.028 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.028 0.025
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.028 0.025
CABLES1 N/A 0.028 0.028
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.028 0.025
MAPK15 N/A 0.028 0.083
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.028 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.028 0.025
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.028 0.028
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.028 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.028 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.028 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.028 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.028 0.075
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.028 0.025
NIPBL N/A 0.028 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.028 0.025
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
PHLDB2 N/A 0.028 0.028
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.028 0.025
FOXQ1 FOXQ1, HFH1: Forkhead box protein Q1 0.027 0.027
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.0263 0.026
SH3BP3 0.026 0.127
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.026 0.052
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.026 0.086
SNRK SNRK, KIAA0096, SNFRK: SNF-related serine/threonine-protein kinase 0.026 0.029
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.026 0.046
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.026 0.052
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.026 0.087
RGS14 N/A 0.026 0.070
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.026 0.046
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.026 0.046
HDAC2 HDAC2: Histone deacetylase 2 0.026 0.063
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.026 0.038
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.026 0.046
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.026 0.077
WDR44 WDR44: WD repeat-containing protein 44 0.026 0.063
COPB2 COPB2: Coatomer subunit beta' 0.026 0.188
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.026 0.070
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.026 0.063
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.026 0.052
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.026 0.026
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.026 0.078
ZFX ZFX: Zinc finger X-chromosomal protein 0.026 0.155
ARMET ARMET, ARP: Protein ARMET precursor 0.026 0.046
PCNA PCNA: Proliferating cell nuclear antigen 0.026 0.046
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.026 0.046
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.026 0.114
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.026 0.063
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.026 0.063
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.026 0.052
CORO1C CORO1C, CRNN4: Coronin-1C 0.026 0.233
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.0425
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.026 0.188
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.026 0.188
IRS2 IRS2: Insulin receptor substrate 2 0.026 0.032
STK10 STK10: Uncharacterized protein STK10 0.026 0.129
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.026 0.046
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.026 0.029
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.026 0.046
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.026 0.046
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.026 0.046
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.026 0.070
GRLF1 N/A 0.026 0.123
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.026 0.078
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.026 0.063
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.026 0.032
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.026 0.063
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.026 0.029
KIF23 N/A 0.026 0.0425
KIAA0853 N/A 0.026 0.087
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.026 0.0425
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.026 0.046
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.026 0.062
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.026 0.225
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.026 0.038
FZR1 N/A 0.026 0.038
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.026 0.233
HDAC4 HDAC4, KIAA0288: Histone deacetylase 4 0.026 0.029
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.026 0.275
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.026 0.029
RUNX1 N/A 0.026 0.029
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.026 0.052
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.026 0.0425
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.026 0.070
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.026 0.063
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.026 0.026
MKI67 MKI67: Antigen KI-67 0.026 0.127
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.026 0.038
EMD EMD, EDMD, STA: Emerin 0.026 0.052
DIAPH1 Diaphanous 1 0.026 0.129
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.026 0.188
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.052
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.026 0.078
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.026 0.069
HIVEP1 N/A 0.026 0.127
SP3 SP3: Transcription factor Sp3 0.026 0.233
WDR1 N/A 0.026 0.430
POLB POLB: DNA polymerase beta 0.026 0.029
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.026 0.029
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.026 0.233
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.026 0.078
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.026 0.046
CDK5 CDK5: Cell division protein kinase 5 0.026 0.029
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.026 0.046
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.026 0.118
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.026 0.063
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.026 0.070
ATM ATM: Serine-protein kinase ATM 0.026 0.046
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.026 0.078
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.032
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.026 0.078
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.026 0.129
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.026 0.078
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.026 0.029
BTG1 BTG1: Protein BTG1 0.0253 0.116
0.347
Total Score 17.60