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Evidence of Interaction Between CTTN and NEK9

The interaction score between CTTN and NEK9 is 2.98.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between CTTN and NEK9 = -0.22

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

1.65E-3
Orthology N/A N/A
Domains Domains present in CTTN and NEK9:
Domains in CTTNDomains in NEK9
IPR001452 SH3
IPR000108 Neutrophil cytosol factor 2
IPR003134 Hs1/Cortactin
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR008271 Serine/threonine protein kinase, active site
IPR000408 Regulator of chromosome condensation, RCC1

The Chi square scores for co-occurrence of domains that are present in CTTN and NEK9 are listed below.

Domain 1Domain 2Chi Square
IPR001452 SH3 IPR000719 Protein kinase 27.1334
IPR001452 SH3 IPR008271 Serine/threonine protein kinase, active site 27.0049
IPR000108 Neutrophil cytosol factor 2 IPR008271 Serine/threonine protein kinase, active site 11.7731
IPR001452 SH3 IPR002290 Serine/threonine protein kinase 11.0285
IPR000108 Neutrophil cytosol factor 2 IPR000719 Protein kinase 4.72045
IPR000108 Neutrophil cytosol factor 2 IPR002290 Serine/threonine protein kinase 3.14533
IPR003134 Hs1/Cortactin IPR000719 Protein kinase 0.281213

The background colour of the table refers to:

  • Blue Domain is only present in CTTN
  • Yellow Domain is only present in NEK9
  • Green Domain is present in both CTTN and NEK9

0.049
Post-translational Modifications

Protein: CTTN

PTMResidueReference
Phosphorylation 334 PubMed, HPRD
Phosphorylation 401 PubMed, HPRD
Phosphorylation 405 PubMed, HPRD
Phosphorylation 418 PubMed, HPRD
Phosphorylation 421 PubMed, HPRD
Phosphorylation 446 PubMed, HPRD
Phosphorylation 453 PubMed, HPRD
Phosphorylation 470 PubMed, HPRD
Phosphorylation 486 PubMed, HPRD
Phosphoserine 405 HPRD
Phosphoserine 418 HPRD
Phosphothreonine 401 HPRD
Phosphotyrosine 215 HPRD
Phosphotyrosine 421 HPRD
Phosphotyrosine 446 HPRD
Phosphotyrosine 453 HPRD

Protein: NEK9

PTMResidueReference
Phosphorylation 210 PubMed, HPRD
Phosphothreonine 210 PubMed, HPRD
Localisation

Protein: CTTN

LocalisationReference
Plasma membrane HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: NEK9

LocalisationReference
Nucleus HPRD
Mitochondrion HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between CTTN and NEK9 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CTTN andNEK9. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CTTN has 1089 interactors and NEK9 has 1399 interactors of which there are 517 common interactors.

Common InteractorName of Common InteractorScore for CTTN-Interactor (?)Score for NEK9-Interactor (?)
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 7.83 0.073
ACTG1 ACTB: Actin, cytoplasmic 1 5.88 0.040
ACTR3 ACTR3, ARP3: Actin-related protein 3 4.67 0.040
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 4.22 0.098
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 4.22 0.098
TAGLN TAGLN, SM22, WS3-10: Transgelin 3.95 0.029
CNN3 CNN3: Calponin-3 3.23 0.029
CSNK1E CSNK1E: Casein kinase I isoform epsilon 2.96 0.114
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 2.81 0.166
HCK N/A 2.81 0.090
CRKL CRKL: Crk-like protein 2.77 0.246
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 2.77 0.064
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 2.61 0.0818
NCK2 NCK2: Cytoplasmic protein NCK2 2.50 0.181
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 2.23 0.304
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 2.23 0.148
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 2.20 0.038
CNN2 CNN2: Calponin-2 2.13 0.049
VAV1 VAV1, VAV: Proto-oncogene vav 1.99 0.304
VAV2 VAV2: Uncharacterized protein VAV2 1.31 0.046
GRAP GRAP: GRB2-related adapter protein 0.674 0.029
VAV3 VAV3: Protein vav-3 0.455 0.029
LCP1 LCP1, PLS2: Plastin-2 0.338 0.040
RDX RDX: Radixin 0.307 0.090
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.307 0.026
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.251 0.058
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.251 0.100
IRS1 IRS1: Insulin receptor substrate 1 0.251 0.109
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.251 0.166
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.191 0.065
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.191 0.044
DAB2 DAB2, DOC2: Disabled homolog 2 0.191 0.110
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.191 0.029
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.191 0.073
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.191 0.051
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.191 0.049
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.191 0.099
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.191 0.051
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.191 0.058
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.191 0.065
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.166 0.046
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.166 0.098
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.166 0.098
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.165 0.098
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.165 0.044
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.165 0.098
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.109
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.165 0.098
STAT3 0.165 0.098
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.109
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.165 0.075
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.165 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.165 0.098
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.165 0.075
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.109
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.165 0.075
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.165 0.098
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.165 0.098
MAPK15 N/A 0.165 0.083
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.109
NF2 NF2, SCH: Merlin 0.165 0.165
ARHGEF7 N/A 0.165 0.098
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.109
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.165 0.075
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.083
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.109
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.109
ELMO1 N/A 0.165 0.148
PSCD2 N/A 0.165 0.109
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.165 0.075
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.160 0.030
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.155 0.056
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.152 0.090
RIN1 RIN1: Ras and Rab interactor 1 0.152 0.136
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.152 0.139
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.152 0.152
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.152 0.065
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.152 0.065
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.152 0.072
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.152 0.072
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.152 0.050
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.152 0.148
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.152 0.086
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.152 0.113
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.152 0.088
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.148 0.041
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.148 0.044
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.148 0.044
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.075
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.139 0.129
PLD2 PLD2: Phospholipase D2 0.136 0.113
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.136 0.041
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.126 0.041
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.123 0.110
PSD TYL: TYL protein 0.123 0.058
BMX N/A 0.123 0.065
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.123 0.114
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.123 0.077
GAB2 N/A 0.123 0.152
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.100
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.126
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.123 0.050
MCF2 MCF2, DBL: Proto-oncogene DBL 0.123 0.072
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.123 0.032
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.123 0.069
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.110 0.056
PLD1 PLD1: Phospholipase D1 0.110 0.113
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.110 0.127
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.110 0.155
DOK1 DOK1: Docking protein 1 0.110 0.275
RPS6KB1 N/A 0.110 0.385
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.110 0.274
ROCK1 ROCK1: Rho-associated protein kinase 1 0.110 0.416
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.110 0.461
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.110 0.126
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.110 0.148
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.110 0.148
JAK1 0.110 0.246
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.109 0.030
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.109 0.062
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.109 0.030
LAT LAT: Linker for activation of T-cells family member 1 0.109 0.034
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.109 0.034
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.109 0.034
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.0688
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.109 0.034
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.109 0.148
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.109 0.034
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.109 0.034
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.109 0.034
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.109 0.034
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.109 0.075
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.109 0.034
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.109 0.025
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.109 0.139
IRS2 IRS2: Insulin receptor substrate 2 0.109 0.152
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.109 0.114
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.109 0.148
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.109 0.171
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.109 0.225
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.109 0.181
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.109 0.069
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.109 0.077
STK16 N/A 0.109 0.127
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.109 0.058
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.109 0.073
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.109 0.127
GAB1 GAB1: GRB2-associated-binding protein 1 0.109 0.123
DAB1 DAB1: Disabled homolog 1 0.109 0.088
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.109 0.166
PTPRZ1 N/A 0.100 0.037
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.099 0.073
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.099 0.385
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.098 0.251
VIL2 N/A 0.098 0.246
APS SH2B2, APS: SH2B adapter protein 2 0.098 0.148
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.098 0.148
MSN MSN: Moesin 0.098 0.246
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.098 0.307
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.098 0.202
VASP VASP: Vasodilator-stimulated phosphoprotein 0.098 0.126
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.098 0.275
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.062
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.0688
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.098 0.025
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.097 0.246
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.097 0.114
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.097 0.233
RASA3 RASA3: Ras GTPase-activating protein 3 0.097 0.148
STAM2 STAM2: Signal transducing adapter molecule 2 0.097 0.041
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.096 0.113
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.088 0.233
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.088 0.148
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.088 0.139
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.088 0.139
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.088 0.260
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.088 0.202
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.088 0.461
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.088 0.430
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.088 0.246
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.088 0.181
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.088 0.111
STAT6 STAT6: Signal transducer and activator of transcription 6 0.088 0.304
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.088 0.275
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.088 0.188
LYN LYN: Tyrosine-protein kinase Lyn 0.088 0.181
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.088 0.246
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.088 0.166
SYK SYK: Tyrosine-protein kinase SYK 0.088 0.246
PSCD4 PSCD4, CYT4: Cytohesin-4 0.088 0.181
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.088 0.202
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.088 0.304
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.088 0.503
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.086 0.056
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.086 0.049
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.086 0.049
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.083 0.036
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.083 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.083 0.075
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.083 0.075
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.083
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.083 0.075
MAP2K5 N/A 0.083 0.109
MAPKAPK5 N/A 0.083 0.083
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.083
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.083 0.075
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.04
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.148
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.083
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.083
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.083 0.075
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.049
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.083 0.075
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.083 0.075
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.049
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.083
CDC2 CDC2: Cell division control protein 2 homolog 0.083 0.075
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.083 0.109
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.081 0.031
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.081 0.097
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.081 0.088
WASPIP N/A 0.078 0.040
CXorf9 N/A 0.078 0.078
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.078 0.260
CSK CSK: Tyrosine-protein kinase CSK 0.078 0.503
GRLF1 N/A 0.077 0.077
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.096
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.077 0.069
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.077 0.044
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.077 0.050
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.0453
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.077 0.041
DAPK2 DAPK2: Death-associated protein kinase 2 0.077 0.055
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.075 0.110
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.075
CDC25C CDC25C: M-phase inducer phosphatase 3 0.075 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.049
CDC25A CDC25A: M-phase inducer phosphatase 1 0.075 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.148
SNX3 N/A 0.075 0.044
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.075 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.075
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.083
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.0727 0.063
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.0727 0.129
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0727 0.039
STAT4 STAT4: Signal transducer and activator of transcription 4 0.0727 0.225
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.0727 0.039
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.0727 0.139
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.0727 0.039
IL9R IL9R: Interleukin-9 receptor precursor 0.072 0.025
ETS2 ETS2: Protein C-ets-2 0.072 0.077
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.041
GHR GHR: Growth hormone receptor precursor 0.072 0.0513
EPOR EPOR: Erythropoietin receptor precursor 0.072 0.025
TXNRD1 TXNRD1: Thioredoxin reductase 1, cytoplasmic precursor 0.070 0.038
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.070 0.246
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.049
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.086
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.0688 0.034
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.065 0.046
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.065 0.063
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.065 0.038
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.065 0.385
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.065 0.077
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.065 0.063
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.065 0.039
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.065 0.031
SOS1 SOS1: Son of sevenless homolog 1 0.065 0.461
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.065 0.110
CENPA CENPA: Histone H3-like centromeric protein A 0.065 0.052
STAT2 STAT2: Signal transducer and activator of transcription 2 0.065 0.307
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.065 0.039
H2AFX H2AFX, H2AX: Histone H2A.x 0.064 0.046
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.064 0.063
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.062 0.049
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.062 0.155
CDKL5 N/A 0.062 0.056
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.062 0.036
MYO3A MYO3A: Myosin IIIA 0.062 0.044
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.062 0.055
DYRK3 N/A 0.062 0.049
CDK5 CDK5: Cell division protein kinase 5 0.062 0.069
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.062 0.077
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.058 0.372
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.058 0.307
PLEK PLEK, P47: Pleckstrin 0.058 0.515
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.058 0.039
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.058 0.372
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.057 0.035
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.057 0.031
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.056 0.050
CDK7 CDK7, MO15: Cell division protein kinase 7 0.056 0.139
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.057
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.056 0.050
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.056 0.077
TST TST: Thiosulfate sulfurtransferase 0.056 0.097
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.056 0.075
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.056 0.233
FUBP1 N/A 0.056 0.157
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.056 0.127
HD HD, IT15: Huntingtin 0.056 0.0446
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.056 0.188
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.056 0.304
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.056 0.188
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.056 0.069
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.056 0.202
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.056 0.078
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.056 0.461
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.056 0.114
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.055 0.096
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.055 0.086
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.055 0.046
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.055 0.114
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.055 0.233
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.055 0.062
CDK6 CDK6: Cell division protein kinase 6 0.055 0.069
CDK4 CDK4: Cell division protein kinase 4 0.055 0.233
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.052 0.025
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
GRB10 N/A 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
EPB41 EPB41, E41P: Protein 4.1 0.051 0.046
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.051 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.051 0.046
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
RAPH1 N/A 0.051 0.051
C9orf88 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.051 0.046
CENTA1 CENTA1: Centaurin-alpha 1 0.051 0.051
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.051 0.054
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.050 0.127
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.050 0.188
CD2AP CD2AP: CD2-associated protein 0.050 0.066
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.050 0.040
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.050 0.188
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.050 0.227
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.050 0.0818
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.050 0.056
BRPF1 BRPF1, BR140: Peregrin 0.050 0.046
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.049 0.027
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.049 0.032
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.049 0.114
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.049 0.155
WEE1 WEE1: Wee1-like protein kinase 0.049 0.139
PRKAA1 N/A 0.049 0.127
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.049 0.040
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.049 0.155
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.049 0.040
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.049 0.114
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.049 0.096
PHB2 PHB2, BAP, REA: Prohibitin-2 0.049 0.0446
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.049 0.051
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.049 0.385
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.049 0.030
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.049 0.062
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.049 0.030
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.049 0.0688
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.034
SYTL4 Endocrine transmitter regulatory protein 0.049 0.028
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.049 0.030
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.049 0.030
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.049 0.049
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.049 0.032
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.049 0.111
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.096
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.049 0.040
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.049 0.139
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.048 0.065
SNCB SNCB: Beta-synuclein 0.048 0.0727
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.034
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
VWF VWF, F8VWF: von Willebrand factor precursor 0.046 0.037
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.046 0.076
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.0453 0.029
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.051
THOP1 THOP1: Thimet oligopeptidase 0.044 0.046
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.044 0.040
CDK2 CDK2: Cell division protein kinase 2 0.044 0.188
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.044 0.139
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.044 0.114
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.044 0.246
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.044 0.040
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.044 0.188
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.044 0.260
ATM ATM: Serine-protein kinase ATM 0.044 0.188
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.044 0.210
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.044 0.129
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.044 0.111
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.044 0.027
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.044 0.233
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.044 0.087
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.044 0.139
STK10 STK10: Uncharacterized protein STK10 0.044 0.188
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.044 0.385
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.044 0.075
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.044 0.047
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.044 0.075
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.044 0.148
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.044 0.0688
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.0425 0.029
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.041 0.031
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.041 0.031
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.087
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.225
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.041 0.071
FNBP1 N/A 0.040 0.129
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.040 0.188
GMIP GMIP: GEM-interacting protein 0.040 0.114
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.040 0.066
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.039 0.066
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.039 0.070
GJA5 GJA5: Gap junction alpha-5 protein 0.038 0.0338
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.038 0.030
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.046
PRDX1 PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1 0.038 0.038
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.038 0.041
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.038 0.029
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.037 0.031
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.036 0.077
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.035 0.137
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.034 0.129
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.034 0.030
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.0338 0.086
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.0338 0.042
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.0333 0.025
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.0333 0.165
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.0333 0.025
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.033 0.063
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.033 0.094
PHF10 N/A 0.033 0.078
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.032 0.034
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.032 0.155
ATP2B1 N/A 0.032 0.025
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.032 0.038
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.031 0.260
FLII FLII, FLIL: Protein flightless-1 homolog 0.031 0.032
SEC24B SEC24B: Protein transport protein Sec24B 0.0308 0.137
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.029 0.191
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.078
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.029 0.052
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.029 0.028
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.029 0.0513
KIF23 N/A 0.029 0.0425
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.029 0.063
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PHLDB2 N/A 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.028 0.025
CASP9 CASP9, MCH6: Caspase-9 precursor 0.028 0.049
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
PPEF1 N/A 0.028 0.028
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.028 0.025
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.049
BCOR N/A 0.028 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.028 0.025
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
TSC2 TSC2, TSC4: Tuberin 0.028 0.044
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.028 0.098
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
GRK6 N/A 0.028 0.025
MAP2K3 N/A 0.028 0.025
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.028 0.04
CAMK2A N/A 0.028 0.025
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.028 0.049
GIT2 N/A 0.028 0.075
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.028 0.025
CASP8 CASP8, MCH5: Caspase-8 precursor 0.028 0.049
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
OSBPL9 N/A 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
FAM43A N/A 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
CD44 N/A 0.0263 0.063
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.026 0.087
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.026 0.063
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.052
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.026 0.069
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.026 0.058
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.026 0.070
YWHAQ YWHAQ: 14-3-3 protein theta 0.026 0.027
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
CAMKK1 N/A 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.025 0.075
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
PRKCB1 N/A 0.025 0.025
RAB5B RAB5B: Ras-related protein Rab-5B 0.025 0.036
ADK ADK: Adenosine kinase 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
NIPBL N/A 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
0.228
Total Score 2.98