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Evidence of Interaction Between CTTN and SIVA

The interaction score between CTTN and SIVA is 2.54.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology N/A N/A
Domains No domains were used in calculating likelihood of interaction 0.028
Post-translational Modifications

Protein: CTTN

PTMResidueReference
Phosphorylation 334 PubMed, HPRD
Phosphorylation 401 PubMed, HPRD
Phosphorylation 405 PubMed, HPRD
Phosphorylation 418 PubMed, HPRD
Phosphorylation 421 PubMed, HPRD
Phosphorylation 446 PubMed, HPRD
Phosphorylation 453 PubMed, HPRD
Phosphorylation 470 PubMed, HPRD
Phosphorylation 486 PubMed, HPRD
Phosphoserine 405 HPRD
Phosphoserine 418 HPRD
Phosphothreonine 401 HPRD
Phosphotyrosine 215 HPRD
Phosphotyrosine 421 HPRD
Phosphotyrosine 446 HPRD
Phosphotyrosine 453 HPRD

Protein: SIVA

PTMResidueReference
Phosphotyrosine 34 PubMed, HPRD
Localisation

Protein: CTTN

LocalisationReference
Plasma membrane HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: SIVA

LocalisationReference
Mitochondrion HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between CTTN and SIVA that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CTTN andSIVA. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CTTN has 1089 interactors and SIVA has 658 interactors of which there are 473 common interactors.

Common InteractorName of Common InteractorScore for CTTN-Interactor (?)Score for SIVA-Interactor (?)
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 7.83 0.028
ACTG1 ACTB: Actin, cytoplasmic 1 5.88 0.028
ACTR3 ACTR3, ARP3: Actin-related protein 3 4.67 0.028
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 4.22 0.028
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 4.22 0.028
TAGLN TAGLN, SM22, WS3-10: Transgelin 3.95 0.028
CNN3 CNN3: Calponin-3 3.23 0.028
CSNK1E CSNK1E: Casein kinase I isoform epsilon 2.96 0.028
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 2.81 0.028
HCK N/A 2.81 0.028
CRKL CRKL: Crk-like protein 2.77 0.028
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 2.77 0.028
NCK2 NCK2: Cytoplasmic protein NCK2 2.50 0.028
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 2.23 0.028
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 2.23 0.028
VAV1 VAV1, VAV: Proto-oncogene vav 1.99 0.028
CRK N/A 1.32 0.028
LCP1 LCP1, PLS2: Plastin-2 0.338 0.028
RDX RDX: Radixin 0.307 0.028
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.307 0.028
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.251 0.028
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.251 0.028
IRS1 IRS1: Insulin receptor substrate 1 0.251 0.028
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.251 0.028
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.191 0.028
DAB2 DAB2, DOC2: Disabled homolog 2 0.191 0.028
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.191 0.028
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.191 0.028
COBL N/A 0.191 0.028
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.191 0.028
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.191 0.028
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.191 0.028
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.191 0.028
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.191 0.028
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.191 0.028
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.165 0.028
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.165 0.028
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.165 0.028
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.028
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.165 0.028
STAT3 0.165 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.028
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.165 0.028
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.165 0.028
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.165 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.165 0.028
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.165 0.028
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.165 0.028
MAPK15 N/A 0.165 0.028
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.028
NF2 NF2, SCH: Merlin 0.165 0.028
ARHGEF7 N/A 0.165 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.028
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.028
ELMO1 N/A 0.165 0.028
PSCD2 N/A 0.165 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.165 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.165 0.028
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.028
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.155 0.028
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.152 0.028
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.152 0.028
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.152 0.028
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.152 0.028
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.152 0.028
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.152 0.028
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.152 0.028
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.152 0.028
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.152 0.028
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.152 0.028
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.152 0.028
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.152 0.028
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.028
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.148 0.028
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.148 0.028
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.028
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.144 0.028
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.139 0.152
HDLBP HDLBP, HBP, VGL: Vigilin 0.139 0.028
PLD2 PLD2: Phospholipase D2 0.136 0.028
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.136 0.028
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.123 0.028
PSD TYL: TYL protein 0.123 0.028
BMX N/A 0.123 0.028
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.123 0.028
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.123 0.028
GAB2 N/A 0.123 0.028
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.028
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.028
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.123 0.028
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.123 0.028
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.123 0.028
SORBS3 SORBS3, SCAM1: Vinexin 0.114 0.028
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.110 0.028
PLD1 PLD1: Phospholipase D1 0.110 0.028
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.110 0.028
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.110 0.028
DOK1 DOK1: Docking protein 1 0.110 0.028
RPS6KB1 N/A 0.110 0.028
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.110 0.028
ROCK1 ROCK1: Rho-associated protein kinase 1 0.110 0.028
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.110 0.028
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.110 0.028
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.110 0.028
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.110 0.028
JAK1 0.110 0.028
IRS2 IRS2: Insulin receptor substrate 2 0.109 0.028
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.109 0.028
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.109 0.028
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.109 0.028
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.109 0.028
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.109 0.028
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.109 0.028
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.109 0.028
STK16 N/A 0.109 0.028
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.109 0.028
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.109 0.028
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.109 0.028
GAB1 GAB1: GRB2-associated-binding protein 1 0.109 0.028
DAB1 DAB1: Disabled homolog 1 0.109 0.028
TTN N/A 0.109 0.028
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.109 0.028
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.099 0.028
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.099 0.028
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.098 0.028
VIL2 N/A 0.098 0.028
APS SH2B2, APS: SH2B adapter protein 2 0.098 0.028
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.098 0.028
MSN MSN: Moesin 0.098 0.028
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.098 0.028
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.098 0.028
VASP VASP: Vasodilator-stimulated phosphoprotein 0.098 0.028
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.098 0.028
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.097 0.028
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.097 0.028
RASA3 RASA3: Ras GTPase-activating protein 3 0.097 0.028
STAM2 STAM2: Signal transducing adapter molecule 2 0.097 0.028
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.096 0.028
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.096 0.028
SPTAN1 N/A 0.096 0.028
TLN2 TLN2: Uncharacterized protein TLN2 0.096 0.028
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.088 0.028
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.088 0.028
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.088 0.028
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.088 0.028
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.088 0.028
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.088 0.028
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.088 0.028
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.088 0.028
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.088 0.028
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.088 0.028
STAT6 STAT6: Signal transducer and activator of transcription 6 0.088 0.028
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.088 0.028
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.088 0.028
LYN LYN: Tyrosine-protein kinase Lyn 0.088 0.028
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.088 0.028
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.088 0.028
SYK SYK: Tyrosine-protein kinase SYK 0.088 0.028
PSCD4 PSCD4, CYT4: Cytohesin-4 0.088 0.028
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.088 0.028
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.088 0.028
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.088 0.028
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.086 0.028
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.086 0.028
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.086 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.028
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.083 0.028
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.083 0.028
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.083 0.028
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.028
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.083 0.028
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.083 0.028
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.083 0.028
MAPKAPK5 N/A 0.083 0.028
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.083 0.028
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.083 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.028
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.083 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.028
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.083 0.028
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.028
CDC2 CDC2: Cell division control protein 2 homolog 0.083 0.028
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.083 0.028
WASPIP N/A 0.078 0.028
CXorf9 N/A 0.078 0.028
CSK CSK: Tyrosine-protein kinase CSK 0.078 0.028
DSTN DSTN, ACTDP, DSN: Destrin 0.078 0.028
GRLF1 N/A 0.077 0.028
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.077 0.028
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.077 0.028
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.077 0.028
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.077 0.028
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.077 0.028
TLN1 TLN1: Uncharacterized protein TLN1 0.077 0.028
DAPK2 DAPK2: Death-associated protein kinase 2 0.077 0.028
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.028
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.028
CDC25C CDC25C: M-phase inducer phosphatase 3 0.075 0.028
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.028
CDC25A CDC25A: M-phase inducer phosphatase 1 0.075 0.028
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.028
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.075 0.028
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.028
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.028
TXNRD1 TXNRD1: Thioredoxin reductase 1, cytoplasmic precursor 0.070 0.028
LIMA1 LIMA1, EPLIN, PP624, SREBP3: LIM domain and actin-binding protein 1 0.070 0.028
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.070 0.028
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.062 0.028
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.062 0.028
CDKL5 N/A 0.062 0.028
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.062 0.028
MYO3A MYO3A: Myosin IIIA 0.062 0.028
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.062 0.028
DYRK3 N/A 0.062 0.028
CDK5 CDK5: Cell division protein kinase 5 0.062 0.028
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.062 0.028
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.056 0.028
CDK7 CDK7, MO15: Cell division protein kinase 7 0.056 0.028
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.028
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.056 0.028
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.056 0.028
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.056 0.028
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.056 0.028
FUBP1 N/A 0.056 0.028
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.056 0.028
HD HD, IT15: Huntingtin 0.056 0.028
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.056 0.028
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.056 0.028
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.056 0.028
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.056 0.028
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.056 0.028
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.056 0.028
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.056 0.028
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.055 0.028
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.055 0.028
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.055 0.028
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.055 0.028
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.055 0.028
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.055 0.028
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.055 0.028
CDK6 CDK6: Cell division protein kinase 6 0.055 0.028
CDK4 CDK4: Cell division protein kinase 4 0.055 0.028
GSN GSN: Gelsolin precursor 0.052 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.052 0.028
SVIL SVIL: Supervillin 0.052 0.028
PARVA PARVA, MXRA2: Alpha-parvin 0.052 0.028
SHC1 SHC1, RP11-307C12.1-001, hCG_1997126: SHC 0.052 0.028
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.052 0.028
MAGED2 N/A 0.052 0.028
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.052 0.028
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.052 0.028
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.050 0.028
CD2AP CD2AP: CD2-associated protein 0.050 0.028
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.050 0.028
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.050 0.028
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.050 0.028
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.050 0.028
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.050 0.028
BRPF1 BRPF1, BR140: Peregrin 0.050 0.028
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.049 0.028
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.049 0.028
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.049 0.028
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.049 0.028
WEE1 WEE1: Wee1-like protein kinase 0.049 0.028
PRKAA1 N/A 0.049 0.028
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.049 0.028
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.049 0.028
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.049 0.028
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.049 0.028
PHB2 PHB2, BAP, REA: Prohibitin-2 0.049 0.028
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.049 0.028
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.049 0.028
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.049 0.028
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.049 0.028
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.049 0.028
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.028
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.049 0.028
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.048 0.028
PMP2 PMP2: Myelin P2 protein 0.048 0.028
SNCB SNCB: Beta-synuclein 0.048 0.028
KLC2 KLC2: Kinesin light chain 2 0.048 0.028
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.048 0.028
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.028
THOP1 THOP1: Thimet oligopeptidase 0.044 0.028
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.044 0.028
CDK2 CDK2: Cell division protein kinase 2 0.044 0.028
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.044 0.028
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.044 0.028
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.044 0.028
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.044 0.028
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.044 0.028
ATM ATM: Serine-protein kinase ATM 0.044 0.028
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.044 0.028
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.044 0.028
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.044 0.028
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.044 0.028
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.044 0.028
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.044 0.028
STK10 STK10: Uncharacterized protein STK10 0.044 0.028
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.044 0.028
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.043 0.028
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.0425 0.028
RGS4 RGS4: Regulator of G-protein signaling 4 0.0425 0.028
ACTN1 ACTN1: Alpha-actinin-1 0.0425 0.028
DPYSL3 DPYSL3, CRMP4, DRP3, ULIP: Dihydropyrimidinase-related protein 3 0.0425 0.028
NOL3 N/A 0.0425 0.028
PARD3 N/A 0.0425 0.028
AHCYL1 AHCYL1, DCAL, XPVKONA: Putative adenosylhomocysteinase 2 0.0425 0.028
SPR SPR: Sepiapterin reductase 0.0425 0.028
CTNND1 0.0425 0.028
CHP CHP: Calcium-binding protein p22 0.0425 0.028
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.028
FNBP1 N/A 0.040 0.028
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.040 0.028
GMIP GMIP: GEM-interacting protein 0.040 0.028
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.040 0.028
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.039 0.028
VIL1 VIL1, VIL: Villin-1 0.039 0.028
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.039 0.028
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.039 0.028
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.039 0.028
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.028
PRDX1 PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1 0.038 0.028
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.038 0.028
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.038 0.028
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.038 0.028
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.035 0.028
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.035 0.028
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.034 0.028
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.0333 0.0333
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.0333 0.0333
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.0333 0.0333
ARVCF ARVCF: Armadillo repeat protein deleted in velo-cardio-facial syndrome 0.032 0.028
CRIP2 CRIP2, CRP2: Cysteine-rich protein 2 0.032 0.028
DPYSL2 DPYSL2, CRMP2: Dihydropyrimidinase-related protein 2 0.032 0.028
DLG1 N/A 0.032 0.028
WWC2 WW and C2 domain containing 2 0.032 0.028
WWC1 WWC1, KIAA0869: WW domain-containing protein 1 0.032 0.028
GMFB GMFB: Glia maturation factor beta 0.032 0.028
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.032 0.028
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.032 0.028
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.028
UNC13B UNC13B, RP11-395N21.1-001, hCG_2011450: Unc-13 homolog B 0.032 0.028
ZYX ZYX: Zyxin 0.032 0.028
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.032 0.028
TJP2 N/A 0.032 0.028
GFAP GFAP: Glial fibrillary acidic protein 0.032 0.028
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.031 0.028
FLII FLII, FLIL: Protein flightless-1 homolog 0.031 0.028
SEC24B SEC24B: Protein transport protein Sec24B 0.0308 0.028
CFL1 CFL1, CFL: Cofilin-1 0.029 0.028
RRAS RRAS: Ras-related protein R-Ras precursor 0.029 0.028
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.029 0.028
PI4KII PI4K2A: Phosphatidylinositol 4-kinase type 2-alpha 0.029 0.028
PMM1 PMM1, PMMH22: Phosphomannomutase 1 0.029 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.028 0.028
C9orf88 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
CDC42 N/A 0.028 0.028
DBNL N/A 0.028 0.028
RAC1 N/A 0.028 0.028
PHLDB2 N/A 0.028 0.028
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.028 0.028
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.028 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.028 0.028
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.028 0.028
AXIN1 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.028 0.028
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.028 0.028
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.028
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.028 0.028
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
BCOR N/A 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.028
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.028 0.028
MYO18A 0.028 0.028
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.028 0.028
TSC2 TSC2, TSC4: Tuberin 0.028 0.028
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
BCR N/A 0.028 0.028
MATK 0.028 0.028
ACTN4 ACTN4: Alpha-actinin-4 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
GRK6 N/A 0.028 0.028
MAP2K3 N/A 0.028 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.028 0.028
PTPN7 N/A 0.028 0.028
CACNB2 N/A 0.028 0.028
SCRIB N/A 0.028 0.028
CAMK2A N/A 0.028 0.028
LMO6 LMO6: LIM domain only protein 6 0.028 0.028
LNX1 N/A 0.028 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.028 0.028
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.028 0.028
GIT2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.028 0.028
CASP8 CASP8, MCH5: Caspase-8 precursor 0.028 0.028
NCF4 N/A 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
DCAMKL1 DCLK1, DCAMKL1, DCDC3A, KIAA0369: Serine/threonine-protein kinase DCLK1 0.026 0.028
RGS16 RGS16, RGSR: Regulator of G-protein signaling 16 0.026 0.028
DNM1 N/A 0.026 0.028
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.028
SH2D4A SH2D4A, SH2A: SH2 domain-containing protein 4A 0.026 0.028
CDO1 CDO1: Cysteine dioxygenase type 1 0.026 0.028
PDE1B PDE1B, PDE1B1, PDES1B: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phos 0.026 0.028
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.026 0.028
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.026 0.028
MARK1 N/A 0.026 0.028
CTNND2 CTNND2, NPRAP: Catenin delta-2 0.026 0.028
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.026 0.028
AFAP AFAP1, AFAP: Actin filament-associated protein 1 0.026 0.028
PKP3 PKP3: Plakophilin-3 0.026 0.028
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.026 0.028
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.026 0.028
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.028
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.026 0.028
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.026 0.028
PDE4A N/A 0.026 0.028
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.026 0.028
LPP LPP: Lipoma-preferred partner 0.026 0.028
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.026 0.028
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.026 0.028
URG4 N/A 0.026 0.028
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.026 0.028
YWHAQ YWHAQ: 14-3-3 protein theta 0.026 0.028
CRMP1 CRMP1, DPYSL1: Dihydropyrimidinase-related protein 1 0.026 0.028
CAMKK1 N/A 0.025 0.028
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.028
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.028
RAD50 RAD50: DNA repair protein RAD50 0.025 0.028
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.025 0.028
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.028
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.028
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.028
PRKCB1 N/A 0.025 0.028
RAB5B RAB5B: Ras-related protein Rab-5B 0.025 0.028
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
ADK ADK: Adenosine kinase 0.025 0.028
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.028
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.028
CFL2 CFL2: Cofilin-2 0.025 0.028
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.028
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.028
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.025 0.028
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.028
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.028
EPN2 N/A 0.025 0.028
0.228
Total Score 2.54