PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between CTTN and WASPIP

The interaction score between CTTN and WASPIP is 10.80.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between CTTN and WASPIP = -0.40

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

1.30E-3

Orthology

Organism	CTTN Orthologue		WASPIP Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
bakers yeast	YCR088W	0.34	YLR337C	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.22E-3

Domains

Domains present in CTTN and WASPIP:

Domains in CTTN

Domains in WASPIP

IPR001452	SH3
IPR000108	Neutrophil cytosol factor 2
IPR003134	Hs1/Cortactin

IPR003124

Actin-binding WH2

The Chi square scores for co-occurrence of domains that are present in CTTN and WASPIP are listed below.

Domain 1		Domain 2		Chi Square
IPR001452	SH3	IPR003124	Actin-binding WH2	199.546
IPR000108	Neutrophil cytosol factor 2	IPR003124	Actin-binding WH2	106.553

The background colour of the table refers to:

Blue Domain is only present in CTTN
Yellow Domain is only present in WASPIP
Green Domain is present in both CTTN and WASPIP

0.165

Post-translational Modifications

Protein: CTTN

PTM	Residue	Reference
Phosphorylation	334	PubMed, HPRD
Phosphorylation	401	PubMed, HPRD
Phosphorylation	405	PubMed, HPRD
Phosphorylation	418	PubMed, HPRD
Phosphorylation	421	PubMed, HPRD
Phosphorylation	446	PubMed, HPRD
Phosphorylation	453	PubMed, HPRD
Phosphorylation	470	PubMed, HPRD
Phosphorylation	486	PubMed, HPRD
Phosphoserine	405	HPRD
Phosphoserine	418	HPRD
Phosphothreonine	401	HPRD
Phosphotyrosine	215	HPRD
Phosphotyrosine	421	HPRD
Phosphotyrosine	446	HPRD
Phosphotyrosine	453	HPRD

Protein: WASPIP

PTM	Residue	Reference
Phosphorylation	488	PubMed, HPRD

Localisation

Protein: CTTN

Localisation	Reference
Plasma membrane	HPRD
Cytoplasm	HPRD
Cytoskeleton	HPRD

Protein: WASPIP

Localisation	Reference
Cytoplasm	HPRD

Transitive Score

The common interactors between CTTN and WASPIP that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CTTN andWASPIP. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CTTN has 1089 interactors and WASPIP has 1007 interactors of which there are 567 common interactors.

Common Interactor	Name of Common Interactor	Score for CTTN-Interactor (?)	Score for WASPIP-Interactor (?)
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	7.83	4.67
ACTG1	ACTB: Actin, cytoplasmic 1	5.88	122.00
ACTR3	ACTR3, ARP3: Actin-related protein 3	4.67	1.62
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	4.22	7.88
GRB2	GRB2, ASH: Growth factor receptor-bound protein 2	4.22	7.88
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	2.96	0.086
GRAP2	GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2	2.81	19.80
HCK	N/A	2.81	19.80
CRKL	CRKL: Crk-like protein	2.77	14.60
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	2.77	5.18
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	2.61	0.063
NCK2	NCK2: Cytoplasmic protein NCK2	2.50	19.80
NCK1	NCK1, NCK: Cytoplasmic protein NCK1	2.23	86.60
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	2.23	24.50
CNN2	CNN2: Calponin-2	2.13	0.025
VAV1	VAV1, VAV: Proto-oncogene vav	1.99	86.60
ACTB	ACTG1, ACTB, ACTG: Actin, cytoplasmic 2	1.98	33.3
CRK	N/A	1.32	0.995
VAV2	VAV2: Uncharacterized protein VAV2	1.31	2.45
ACTG1	ACTR2, ARP2: Actin-related protein 2	0.849	0.123
ACTA2	ACTA2, ACTSA, GIG46, ACTVS: Actin, aortic smooth muscle	0.786	0.849
GRAP	GRAP: GRB2-related adapter protein	0.674	9.63
ACTG2	ACTG2, ACTA3, ACTL3, ACTSG: Actin, gamma-enteric smooth muscle	0.508	0.754
ACTC	ACTC1, ACTC: Actin, alpha cardiac muscle 1	0.508	0.837
ACTA1	ACTA1, ACTA: Actin, alpha skeletal muscle	0.508	0.837
VAV3	VAV3: Protein vav-3	0.455	2.36
LCP1	LCP1, PLS2: Plastin-2	0.338	0.276
RDX	RDX: Radixin	0.307	0.044
PTK2	PTK2, FAK, FAK1: Focal adhesion kinase 1	0.307	0.050
PDGFRA	PDGFRA: Alpha-type platelet-derived growth factor receptor precursor	0.274	0.029
EPB41L3	EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3	0.251	0.044
IRS1	IRS1: Insulin receptor substrate 1	0.251	0.049
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.251	0.123
PRKD1	PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1	0.191	0.040
MAP3K10	MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10	0.191	0.088
DAB2	DAB2, DOC2: Disabled homolog 2	0.191	0.049
LIMK1	LIMK1, LIMK: LIM domain kinase 1	0.191	0.049
EPB41L2	EPB41L2: Band 4.1-like protein 2	0.191	0.050
COBL	N/A	0.191	0.110
DNMBP	DNMBP, KIAA1010: Dynamin-binding protein	0.191	0.110
PAK4	PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4	0.191	0.088
MAPK8IP1	MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1	0.191	0.078
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.191	0.114
PIK3R2	PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta	0.191	0.099
SNTA1	SNTA1, SNT1: Alpha-1-syntrophin	0.191	0.050
TEK	TEK, TIE2: Angiopoietin-1 receptor precursor	0.166	0.033
EPHB4	EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor	0.166	0.026
EPHB2	EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor	0.166	0.026
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.166	0.065
ARHGEF12	ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12	0.166	0.058
EPB41L1	EPB41L1, KIAA0338: Band 4.1-like protein 1	0.165	0.075
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	0.165	0.075
ITSN2	ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2	0.165	0.148
LNK	SH2B3, LNK: SH2B adapter protein 3	0.165	0.165
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.165	0.165
STAT3		0.165	0.148
ITSN1	ITSN1, ITSN, SH3D1A: Intersectin-1	0.165	0.165
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.165	0.165
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.165	0.075
SPTBN1	SPTBN1, SPTB2: Spectrin beta chain, brain 1	0.165	0.075
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.165	0.025
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.165	0.165
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.165	0.075
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.165	0.075
RASA1	RASA1, RASA: Ras GTPase-activating protein 1	0.165	0.165
MAPK15	N/A	0.165	0.083
PTPN6	PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6	0.165	0.165
NF2	NF2, SCH: Merlin	0.165	0.083
ARHGEF7	N/A	0.165	0.075
PSCD1	PSCD1, D17S811E: Cytohesin-1	0.165	0.083
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.165	0.075
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.165	0.028
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.165	0.165
SLA2	SLA2, C20orf156, SLAP2: Src-like-adapter 2	0.165	0.165
ELMO1	N/A	0.165	0.075
PSCD2	N/A	0.165	0.083
ABI1	ABI1, SSH3BP1: Abl interactor 1	0.165	0.165
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.165	0.025
DNM3	DNM3: Uncharacterized protein DNM3	0.165	0.083
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.155	0.049
RIN1	RIN1: Ras and Rab interactor 1	0.152	0.136
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.152	0.233
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.152	0.088
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.152	0.055
PRKCZ	PRKCZ, PKC2: Protein kinase C zeta type	0.152	0.044
PLCB1	PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-	0.152	0.050
INSL3	JAK3: Tyrosine-protein kinase JAK3	0.152	0.109
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.152	0.109
PAK7	PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7	0.152	0.099
BRAF	BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase	0.152	0.114
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.152	0.056
FER	FER, TYK3: Proto-oncogene tyrosine-protein kinase FER	0.152	0.110
ROCK2	ROCK2, KIAA0619: Rho-associated protein kinase 2	0.152	0.050
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.148	0.075
RASGRP3	RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3	0.148	0.025
RASGRP2	RASGRP2: RAS guanyl-releasing protein 2	0.148	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.148	0.075
MYO1F	MYO1F: Myosin-If	0.140	6.55
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.139	0.078
PLD2	PLD2: Phospholipase D2	0.136	0.056
STAM	STAM, STAM1: Signal transducing adapter molecule 1	0.136	0.110
EPHA2	EPHA2, ECK: Ephrin type-A receptor 2 precursor	0.126	0.029
EPHB3	EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor	0.126	0.026
PDGFRB	PDGFRB: Beta-type platelet-derived growth factor receptor precursor	0.126	0.029
MET	MET: Hepatocyte growth factor receptor precursor	0.126	0.033
ERBB2	ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor	0.126	0.029
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.123	0.049
PSD	TYL: TYL protein	0.123	0.049
BMX	N/A	0.123	0.109
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.123	0.069
NEK3	NEK3: Serine/threonine-protein kinase Nek3	0.123	0.062
GAB2	N/A	0.123	0.096
IRS4	IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4	0.123	0.062
SOCS3	SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3	0.123	0.152
PAK6	PAK6, PAK5: Serine/threonine-protein kinase PAK 6	0.123	0.099
MCF2	MCF2, DBL: Proto-oncogene DBL	0.123	0.109
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	0.123	0.077
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.123	0.069
MYO1E	N/A	0.119	0.593
SORBS3	SORBS3, SCAM1: Vinexin	0.114	0.088
PRKCA	PRKCA, PKCA, PRKACA: Protein kinase C alpha type	0.110	0.056
PLD1	PLD1: Phospholipase D1	0.110	0.069
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.110	0.210
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.110	0.210
DOK1	DOK1: Docking protein 1	0.110	0.188
RPS6KB1	N/A	0.110	0.233
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.110	0.251
ROCK1	ROCK1: Rho-associated protein kinase 1	0.110	0.260
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.110	0.385
SH2D2A	SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A	0.110	0.416
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.110	0.515
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.110	0.461
JAK1		0.110	1.81
EGFR	EGFR, ERBB1: Epidermal growth factor receptor precursor	0.109	0.044
EPHA8	EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor	0.109	0.044
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.109	0.098
FGFR3	FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor	0.109	0.049
RET	RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor	0.109	0.049
FGFR1	FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor	0.109	0.049
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.109	0.044
AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor	0.109	0.049
ERBB3	ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor	0.109	0.044
IRS2	IRS2: Insulin receptor substrate 2	0.109	0.077
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.109	0.062
PLCB3	PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	0.109	0.086
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.109	0.078
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.109	0.139
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.109	0.086
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.109	0.251
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.109	0.026
STK16	N/A	0.109	0.127
CNKSR2	CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2	0.109	0.049
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	0.109	0.136
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.109	0.127
GAB1	GAB1: GRB2-associated-binding protein 1	0.109	0.062
DAB1	DAB1: Disabled homolog 1	0.109	0.044
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.109	0.152
KDR	KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor	0.100	0.029
ERBB4	ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor	0.100	0.026
NPR1	NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor	0.100	0.026
EPHA1	EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor	0.100	0.029
MST1R	MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor	0.100	0.026
INSR	INSR: Insulin receptor precursor	0.100	0.026
IGF1R	IGF1R: Insulin-like growth factor 1 receptor precursor	0.100	0.029
WASL	WASL: Neural Wiskott-Aldrich syndrome protein	0.099	148.00
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.099	0.078
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.098	0.210
VIL2	N/A	0.098	0.139
APS	SH2B2, APS: SH2B adapter protein 2	0.098	0.225
IQSEC1	IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein	0.098	0.139
MSN	MSN: Moesin	0.098	0.822
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.098	0.127
PLCG1	PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	0.098	0.307
VASP	VASP: Vasodilator-stimulated phosphoprotein	0.098	0.515
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.098	0.233
OSBP	OSBP, OSBP1: Oxysterol-binding protein 1	0.097	0.139
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.097	0.086
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.097	0.139
RASA3	RASA3: Ras GTPase-activating protein 3	0.097	0.372
STAM2	STAM2: Signal transducing adapter molecule 2	0.097	0.136
PRKCI	PRKCI, DXS1179E: Protein kinase C iota type	0.096	0.056
SPTAN1	N/A	0.096	0.098
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.088	0.188
ARHGAP12	ARHGAP12: Rho GTPase-activating protein 12	0.088	0.225
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.088	0.139
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.088	0.233
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.088	0.430
SH3BP2	SH3BP2: Uncharacterized protein SH3BP2	0.088	0.515
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.088	0.233
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.088	0.087
ARHGEF6	ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6	0.088	0.461
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.088	0.372
RAPGEF6	RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6	0.088	0.078
STAT6	STAT6: Signal transducer and activator of transcription 6	0.088	1.62
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.088	0.385
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.088	0.822
LYN	LYN: Tyrosine-protein kinase Lyn	0.088	0.461
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.088	0.275
SLA	SLA, SLAP, SLAP1: SRC-like-adapter	0.088	0.515
SYK	SYK: Tyrosine-protein kinase SYK	0.088	0.416
PSCD4	PSCD4, CYT4: Cytohesin-4	0.088	0.385
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.088	0.515
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.088	0.416
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.088	0.852
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.086	0.056
CAMK1	CAMK1: Calcium/calmodulin-dependent protein kinase type 1	0.086	0.049
GSK3A	GSK3A: Glycogen synthase kinase-3 alpha	0.086	0.049
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.028
BIN1	BIN1, AMPHL: Myc box-dependent-interacting protein 1	0.083	0.148
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.083	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.083	0.075
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.083	0.025
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.083	0.028
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.083	0.025
NEDD9	NEDD9, CASL: Enhancer of filamentation 1	0.083	0.165
MAP2K5	N/A	0.083	0.083
BAIAP2	BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2	0.083	0.148
MAPKAPK5	N/A	0.083	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.083	0.028
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.083	0.025
AMPH	AMPH, AMPH1: Amphiphysin	0.083	0.165
EEF2K	EEF2K: Elongation factor 2 kinase	0.083	0.075
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.083	0.028
USP16	USP16: Ubiquitin carboxyl-terminal hydrolase 16	0.083	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.083	0.028
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.083	0.025
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.083	0.028
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.083	0.025
HNRPK	HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K	0.083	0.028
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.083	0.025
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.083	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.083	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.083	0.083
CDC2	CDC2: Cell division control protein 2 homolog	0.083	0.075
SNCA	SNCA, NACP, PARK1: Alpha-synuclein	0.083	0.028
EPHA7	EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor	0.081	0.026
FLT1	FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor	0.081	0.029
EPHB1	EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor	0.081	0.026
MERTK	MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor	0.081	0.033
APBA2	APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2	0.081	0.033
EPHA4	EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor	0.081	0.026
TIAM1	TIAM1: T-lymphoma invasion and metastasis-inducing protein 1	0.081	0.081
CXorf9	N/A	0.078	1.62
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.078	0.917
CSK	CSK: Tyrosine-protein kinase CSK	0.078	1.62
GRLF1	N/A	0.077	0.055
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.077
MAP2K4	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k	0.077	0.069
MOS	MOS: Proto-oncogene serine/threonine-protein kinase mos	0.077	0.056
LIMK2	LIMK2: LIM domain kinase 2	0.077	0.032
TLN1	TLN1: Uncharacterized protein TLN1	0.077	0.046
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.075	0.025
SH3KBP1	SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1	0.075	0.148
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.075	0.025
CAMK4	CAMK4: Calcium/calmodulin-dependent protein kinase type IV	0.075	0.075
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.075	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.075	0.025
SNX3	N/A	0.075	0.025
LTA4H	LTA4H, LTA4: Leukotriene A-4 hydrolase	0.075	0.025
NLN	NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor	0.075	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.075	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.075	0.025
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.075	0.025
CD58	CD58, LFA3: Lymphocyte function-associated antigen 3 precursor	0.0727	0.036
SIRPB1	SIRPB1: Signal regulatory protein beta-1 precursor	0.0727	0.027
CD7	CD7: T-cell antigen CD7 precursor	0.0727	0.0446
CD3G	CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor	0.0727	0.027
SLAMF1	SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor	0.0727	0.027
STAT4	STAT4: Signal transducer and activator of transcription 4	0.0727	0.246
CSF2RB	CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor	0.0727	0.027
LILRB1	N/A	0.0727	0.027
FGFR4	FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor	0.072	0.029
KIT	KIT: Mast/stem cell growth factor receptor precursor	0.072	0.029
WAS	WAS, IMD2: Wiskott-Aldrich syndrome protein	0.070	431.00
EPHA5	EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor	0.0688	0.030
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.065	0.040
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.065	0.040
CSF1R	CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor	0.065	0.067
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.065	0.037
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.065	0.040
IL2RB	IL2RB: Interleukin-2 receptor subunit beta precursor	0.065	0.036
SOS1	SOS1: Son of sevenless homolog 1	0.065	0.246
FLT3	FLT3, STK1: FL cytokine receptor precursor	0.065	0.041
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.065	0.073
STAT2	STAT2: Signal transducer and activator of transcription 2	0.065	0.166
ADAM17	ADAM17, CSVP, TACE: ADAM 17 precursor	0.065	0.032
SRC	N/A	0.064	0.119
DKFZp686D0972	ACT: Actin-like protein (Fragment)	0.064	0.119
LOC400581	LOC400581: LOC400581 protein (Fragment)	0.064	0.119
PRKG1	PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme	0.062	0.056
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.062	0.096
CDKL5	N/A	0.062	0.055
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.062	0.032
GRK1	GRK1, RHOK: Rhodopsin kinase precursor	0.062	0.062
DYRK3	N/A	0.062	0.044
CDK5	CDK5: Cell division protein kinase 5	0.062	0.056
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.062	0.062
HLA-DMA	DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP	0.058	0.027
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.058	0.304
ICAM2	ICAM2: Intercellular adhesion molecule 2 precursor	0.058	0.074
HLA-G	HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec	0.058	0.157
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.058	1.19
HLA-C	HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor	0.058	0.157
CD2	CD2, SRBC: T-cell surface antigen CD2 precursor	0.058	0.0446
PLEK	PLEK, P47: Pleckstrin	0.058	0.253
HLA-DMB	HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec	0.058	0.027
CD3E	CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor	0.058	0.027
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.058	0.503
HLA-A	HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor	0.058	0.157
HLA-DPB1	HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor	0.058	0.036
CD47	CD47, MER6: Leukocyte surface antigen CD47 precursor	0.058	0.0446
ICAM3	ICAM3: Intercellular adhesion molecule 3 precursor	0.058	0.157
PRKAA2	PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2	0.056	0.044
CDK7	CDK7, MO15: Cell division protein kinase 7	0.056	0.114
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.056	0.086
PRKCE	PRKCE, PKCE: Protein kinase C epsilon type	0.056	0.050
SGK	SGK, SGK1: Serine/threonine-protein kinase Sgk1	0.056	0.086
NCF1	Neutrophil cytosolic factor 1 variant (Fragment)	0.056	0.416
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.056	0.139
FUBP1	N/A	0.056	0.087
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.056	0.052
HD	HD, IT15: Huntingtin	0.056	0.070
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.056	0.063
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.056	0.385
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.056	0.038
MAP2K6	MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki	0.056	0.029
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.056	0.515
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.056	0.087
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.056	0.129
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.056	0.139
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.055	0.139
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.055	0.046
USP21	USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21	0.055	0.032
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.055	0.109
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.055	0.046
ICK	ICK, KIAA0936: Serine/threonine-protein kinase ICK	0.055	0.026
CDK6	CDK6: Cell division protein kinase 6	0.055	0.062
CDK4	CDK4: Cell division protein kinase 4	0.055	0.086
GSN	GSN: Gelsolin precursor	0.052	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.052	0.025
SVIL	SVIL: Supervillin	0.052	0.025
SORL1	SORL1: Sortilin-related receptor precursor	0.052	0.141
HLA-B	HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor	0.052	0.157
CRLF3	N/A	0.052	0.157
MAP3K9	MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9	0.051	0.051
CDC42EP1	CDC42EP1, BORG5, CEP1, MSE55: Cdc42 effector protein 1	0.051	0.051
GRB10	N/A	0.051	0.051
CRK	CRK: Proto-oncogene C-crk	0.051	0.051
CDC42BPA	CDC42BPA: Serine/threonine-protein kinase MRCK alpha	0.051	0.051
BCR	BCR, BCR1, D22S11: Breakpoint cluster region protein	0.051	0.051
EVL	EVL, RNB6: Ena/VASP-like protein	0.051	0.051
TNK2	TNK2, ACK1: Activated CDC42 kinase 1	0.051	0.046
PTPN11	PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11	0.051	0.051
SHC1	SHC1, SHC, SHCA: SHC-transforming protein 1	0.051	0.051
CENTA1	CENTA1: Centaurin-alpha 1	0.051	0.039
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.050	0.038
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.050	0.086
CD2AP	CD2AP: CD2-associated protein	0.050	0.275
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.050	0.046
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.050	0.046
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.050	0.063
IQGAP1	IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1	0.050	0.129
HIPK3	HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3	0.050	0.069
BRPF1	BRPF1, BR140: Peregrin	0.050	0.046
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.049	0.191
TBK1	TBK1, NAK: Serine/threonine-protein kinase TBK1	0.049	0.087
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.049	0.139
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.049	0.052
WEE1	WEE1: Wee1-like protein kinase	0.049	0.077
PRKAA1	N/A	0.049	0.096
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.049	0.052
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.049	0.046
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.049	0.086
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.049	0.026
PHB2	PHB2, BAP, REA: Prohibitin-2	0.049	0.052
EEA1	EEA1, ZFYVE2: Early endosome antigen 1	0.049	0.029
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.049	0.056
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.049	0.233
PRKCG	PRKCG, PKCG: Protein kinase C gamma type	0.049	0.049
EPS15	EPS15, AF1P: Epidermal growth factor receptor substrate 15	0.049	0.046
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.049	0.139
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.049	0.069
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.049	0.029
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.049	0.139
PLCG2	PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2	0.046	0.046
RPS6KA3	RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3	0.046	0.094
PRKCQ	PRKCQ, PRKCT: Protein kinase C theta type	0.044	0.046
THOP1	THOP1: Thimet oligopeptidase	0.044	0.029
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.044	0.063
CDK2	CDK2: Cell division protein kinase 2	0.044	0.086
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.044	0.233
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.044	0.056
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.044	0.038
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.044	0.078
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.044	0.086
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.044	0.087
ATM	ATM: Serine-protein kinase ATM	0.044	0.385
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.044	0.052
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.044	0.087
SNX17	SNX17, KIAA0064: Sorting nexin-17	0.044	0.063
PSTPIP1	PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1	0.044	0.852
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.044	0.129
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.044	0.070
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.044	0.385
STK10	STK10: Uncharacterized protein STK10	0.044	2.46
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.044	0.233
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.044	0.044
FTH1	FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain	0.0425	0.032
FNBP1	N/A	0.040	0.763
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.040	0.822
GMIP	GMIP: GEM-interacting protein	0.040	0.385
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.040	0.129
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.039	0.763
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.039	0.052
GAPD	GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase	0.038	0.029
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.038	0.029
ABL1	N/A	0.038	0.071
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.035	1.62
ABL2	N/A	0.035	0.047
ALOX5	ALOX5, LOG5: Arachidonate 5-lipoxygenase	0.035	0.070
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.034	0.078
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.033	0.040
CD40LG	CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand	0.033	0.027
PTPN1	PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1	0.033	0.027
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.032	0.075
TGFBR1	TGFBR1: TGF-beta receptor type-1 precursor	0.032	0.051
DLG1	N/A	0.032	0.029
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.032	0.032
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.032	0.0425
ZYX	ZYX: Zyxin	0.032	0.052
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.031	0.052
FLII	FLII, FLIL: Protein flightless-1 homolog	0.031	0.063
SEC24B	SEC24B: Protein transport protein Sec24B	0.0308	0.078
ACTR1A	ACTR1A, CTRN1: Alpha-centractin	0.0308	0.028
CDC42EP3	CDC42EP3, BORG2, CEP3: Cdc42 effector protein 3	0.030	0.129
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.029	0.040
IFNGR1	IFNGR1: Interferon-gamma receptor alpha chain precursor	0.029	0.0446
ADRB2	ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor	0.029	0.040
CFL1	CFL1, CFL: Cofilin-1	0.029	0.038
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
NCOA5	NCOA5, KIAA1637: Nuclear receptor coactivator 5	0.028	0.028
C9orf88	N/A	0.028	0.028
STAP2	Uncharacterized protein ENSP00000317912	0.028	0.028
CASP7	N/A	0.028	0.028
CDC42	N/A	0.028	0.028
DBNL	N/A	0.028	0.025
RAC1	N/A	0.028	0.025
PHLDB2	N/A	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
DCTN1	DCTN1: Dynactin subunit 1	0.028	0.025
GOPC	GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein	0.028	0.025
RGS18	RGS18, RGS13: Regulator of G-protein signaling 18	0.028	0.028
KIAA0031	EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component	0.028	0.025
CASP9	CASP9, MCH6: Caspase-9 precursor	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
AP1GBP1	AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1	0.028	0.025
PPEF1	N/A	0.028	0.028
DPP8	DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8	0.028	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.028	0.025
CAPN3	CAPN3, CANP3, CANPL3, NCL1: Calpain-3	0.028	0.028
DNAJC13	DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13	0.028	0.028
COTL1	COTL1, CLP: Coactosin-like protein	0.028	0.028
UACA	UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats	0.028	0.028
EHD4	EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4	0.028	0.025
AXIN1		0.028	0.028
RSU1	RSU1, RSP1: Ras suppressor protein 1	0.028	0.025
CASP6	CASP6, MCH2: Caspase-6 precursor	0.028	0.028
G3BP2	G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2	0.028	0.025
KCNIP3	KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin	0.028	0.028
AKAP12	AKAP12, AKAP250: A-kinase anchor protein 12	0.028	0.028
PDE4B	PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0.028	0.025
NDNL2	NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1	0.028	0.025
PKP4	PKP4: Plakophilin-4	0.028	0.028
NASP	NASP: Nuclear autoantigenic sperm protein	0.028	0.028
ABLIM1	ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1	0.028	0.028
SLC9A3R2	SLC9A3R2: SLC9A3R2 protein (Fragment)	0.028	0.028
BCOR	N/A	0.028	0.025
SIVA	SIVA1, SIVA: Apoptosis regulatory protein Siva	0.028	0.028
RASD1	RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor	0.028	0.025
PDZD2	CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P	0.028	0.028
CASP14	CASP14: Caspase-14 precursor	0.028	0.028
S100A16	S100A16, AAG13: Protein S100-A16	0.028	0.028
LRRC7	LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7	0.028	0.025
MYO18A		0.028	0.028
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.028	0.025
FASN	FASN, FAS: Fatty acid synthase	0.028	0.028
TSC2	TSC2, TSC4: Tuberin	0.028	0.028
PARD6A	PARD6A, PAR6A: Partitioning defective 6 homolog alpha	0.028	0.025
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
BCR	N/A	0.028	0.028
MATK		0.028	0.028
ACTN4	ACTN4: Alpha-actinin-4	0.028	0.025
AHSA2	AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236	0.028	0.028
PDE5A	PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase	0.028	0.028
SH3PX3	SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3.	0.028	0.025
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
GRK6	N/A	0.028	0.025
MAP2K3	N/A	0.028	0.025
KRT6E	KRT6C, KRT6E: Keratin, type II cytoskeletal 6C	0.028	0.028
PTPN7	N/A	0.028	0.028
CACNB2	N/A	0.028	0.028
SCRIB	N/A	0.028	0.025
CAMK2A	N/A	0.028	0.025
LMO6	LMO6: LIM domain only protein 6	0.028	0.025
LNX1	N/A	0.028	0.028
CASP1	CASP1, IL1BC, IL1BCE: Caspase-1 precursor	0.028	0.028
RSN	CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1	0.028	0.025
GIT2	N/A	0.028	0.025
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.028	0.025
CASP8	CASP8, MCH5: Caspase-8 precursor	0.028	0.028
NCF4	N/A	0.028	0.028
SH2D3A	SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A	0.028	0.028
YWHAG	YWHAG: 14-3-3 protein gamma	0.028	0.028
SPAG6	SPAG6, PF16: Sperm-associated antigen 6	0.028	0.028
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.028	0.028
SH2D1B	SH2D1B, EAT2: SH2 domain-containing protein 1B	0.027	0.027
SHANK1	SHANK1: SH3 and multiple ankyrin repeat domains protein 1	0.027	0.027
ACTL7A	ACTL7A: Actin-like protein 7A	0.027	0.027
CASKIN1	N/A	0.027	0.027
ARHGEF1	ARHGEF1: Rho guanine nucleotide exchange factor 1	0.027	0.027
RASGRF2	RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment)	0.027	0.027
SPRED1	SPRED1: Sprouty-related, EVH1 domain-containing protein 1	0.027	0.027
ACTRT2	ACTRT2, ARPM2: Actin-related protein T2	0.027	0.027
SOCS4	SOCS4, SOCS7: Suppressor of cytokine signaling 4	0.027	0.027
CISH	CISH, G18: Cytokine-inducible SH2-containing protein	0.027	0.027
PXK	PXK: PX domain-containing protein kinase-like protein	0.027	0.027
ARPM1	ARPM1: Actin-related protein M1	0.027	0.027
SRMS	SRMS, C20orf148: Tyrosine-protein kinase Srms	0.027	0.027
BRDG1	STAP1, BRDG1: Signal-transducing adaptor protein 1	0.027	0.027
RASGRF1	RASGRF1, CDC25: Guanine nucleotide-releasing protein	0.027	0.027
ABI3	ABI3, NESH: ABI gene family member 3	0.027	0.027
ACTL7B	ACTL7B: Actin-like protein 7B	0.027	0.027
CD44	N/A	0.0263	0.036
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.026	0.032
ITGB2	ITGB2, CD18, MFI7: Integrin beta-2 precursor	0.026	0.066
IL10RA	IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor	0.026	0.074
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.026	0.032
CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1	0.026	0.038
MICAL-L1	MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1	0.026	0.026
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.026	0.032
CAPN2	CAPN2, CANPL2: Calpain-2 catalytic subunit precursor	0.026	0.063
YWHAQ	YWHAQ: 14-3-3 protein theta	0.026	0.032
DLG2	DLG2: Disks large homolog 2	0.025	0.041
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.025
CAMKK1	N/A	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	6.64
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
RAD50	RAD50: DNA repair protein RAD50	0.025	0.025
GART	GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include	0.025	0.025
CHTF18	RUVBL, CHTF18: Protein CTF18 homolog.	0.025	0.025
HSPA8	HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein	0.025	0.025
SPAST	SPAST, KIAA1083, SPG4: Spastin	0.025	0.025
PRKCB1	N/A	0.025	0.025
RAB5B	RAB5B: Ras-related protein Rab-5B	0.025	0.025
WRNIP1	WRNIP1, WHIP: ATPase WRNIP1	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
UBE2R2	UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
NIPBL	N/A	0.025	0.025
CFL2	CFL2: Cofilin-2	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
KCNAB2	KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2	0.025	0.025
UBE2A	UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A	0.025	0.025
DCP1B	DCP1B: mRNA-decapping enzyme 1B	0.025	0.025
EPN2	N/A	0.025	0.025

0.347

Total Score

10.80