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Evidence of Interaction Between STAT5A and SOCS5

The interaction score between STAT5A and SOCS5 is 3.62.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between STAT5A and SOCS5 = -0.11

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.48E-3
Orthology N/A N/A
Domains Domains present in STAT5A and SOCS5:
Domains in STAT5ADomains in SOCS5
IPR008967 p53-like transcription factor, DNA-binding
IPR000980 SH2 motif
IPR001217 STAT protein
IPR011992 EF-Hand_type.
IPR012345 STAT_DNA_bd.
IPR000980 SH2 motif
IPR001496 SOCS protein, C-terminal

The Chi square scores for co-occurrence of domains that are present in STAT5A and SOCS5 are listed below.

Domain 1Domain 2Chi Square
IPR000980 SH2 motif IPR000980 SH2 motif 36.445
IPR001217 STAT protein IPR000980 SH2 motif 12.56
IPR012345 STAT_DNA_bd. IPR000980 SH2 motif 12.56
IPR011992 EF-Hand_type. IPR000980 SH2 motif 5.54712
IPR000980 SH2 motif IPR001496 SOCS protein, C-terminal 4.01542
IPR008967 p53-like transcription factor, DNA-binding IPR000980 SH2 motif 0.942535

The background colour of the table refers to:

  • Blue Domain is only present in STAT5A
  • Yellow Domain is only present in SOCS5
  • Green Domain is present in both STAT5A and SOCS5

 0.027
Post-translational Modifications

Protein: STAT5A

PTMResidueReference
Dephosphorylation 694 PubMed, HPRD
Phosphorylation 694 PubMed, HPRD
Phosphorylation 726 PubMed, HPRD
Phosphorylation 780 PubMed, HPRD
Phosphotyrosine 694 PubMed, HPRD

Protein: SOCS5

PTMResidueReference
Localisation

Protein: STAT5A

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: SOCS5

LocalisationReference
Cytoplasm HPRD
Transitive Score

The common interactors between STAT5A and SOCS5 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between STAT5A andSOCS5. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , STAT5A has 1739 interactors and SOCS5 has 372 interactors of which there are 265 common interactors.

Common InteractorName of Common InteractorScore for STAT5A-Interactor (?)Score for SOCS5-Interactor (?)
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 1.16E3 0.129
JAK2 JAK2: Tyrosine-protein kinase JAK2 1.04E3 0.174
ZAP70 ZAP70: Uncharacterized protein ZAP70 856.00 0.174
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 600.00 0.200
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 563.00 0.265
KIT KIT: Mast/stem cell growth factor receptor precursor 487.00 0.251
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 375.00 0.402
INSR INSR: Insulin receptor precursor 277.00 0.143
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 250.00 0.330
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 112.00 0.041
STAT3 12.60 0.027
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 3.64 0.174
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 2.42 0.157
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 2.17 0.174
SYK SYK: Tyrosine-protein kinase SYK 2.17 0.174
CSK CSK: Tyrosine-protein kinase CSK 2.17 0.174
HCK N/A 1.78 0.157
LYN LYN: Tyrosine-protein kinase Lyn 1.78 0.174
JAK1 1.78 0.197
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 1.78 0.157
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 1.50 0.305
TXK TXK, PTK4: Tyrosine-protein kinase TXK 1.35 0.174
FLT3 FLT3, STK1: FL cytokine receptor precursor 1.33 0.162
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 1.30 0.265
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 1.30 0.265
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 1.20 0.174
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 1.17 0.265
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 1.17 0.265
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.980 0.217
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.980 0.217
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.980 0.217
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.878 0.217
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.878 0.217
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.878 0.217
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.878 0.217
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.874 0.197
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.874 0.197
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.859 0.197
BMX N/A 0.775 0.197
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.775 0.244
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.775 0.174
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.770 0.305
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.694 0.491
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.655 0.251
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.655 0.129
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.654 0.143
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.617 0.0288
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.617 0.0288
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.617 0.0288
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.617 0.0288
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.586 0.200
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.586 0.200
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.586 0.251
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.586 0.200
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.586 0.200
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.581 0.200
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.577 0.129
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.577 0.143
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.577 0.143
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.577 0.162
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.553 0.0288
FLT4 VEGFR3 long form 0.553 0.0288
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.520 0.162
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.520 0.143
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.520 0.162
MET MET: Hepatocyte growth factor receptor precursor 0.519 0.162
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.484 0.140
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.465 0.251
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.440 0.174
FYN N/A 0.402 0.197
RYK RYK, JTK5A: Tyrosine-protein kinase RYK precursor 0.330 0.251
ALK ALK: ALK tyrosine kinase receptor precursor 0.318 0.0924
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.305 0.174
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.275 0.0308
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
TNK1 TNK1: Non-receptor tyrosine-protein kinase TNK1 0.237 0.265
LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 0.225 0.129
FGFR2 N/A 0.217 0.217
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.200 0.129
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.195 0.217
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.0308
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.041
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.171 0.0308
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.171 0.0308
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.171 0.041
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.171 0.0308
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.165 0.027
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.165 0.027
MAPKAPK5 N/A 0.165 0.027
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.027
NF2 NF2, SCH: Merlin 0.165 0.027
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.165 0.027
AMPH AMPH, AMPH1: Amphiphysin 0.165 0.027
MAP2K5 N/A 0.165 0.027
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.027
PSCD2 N/A 0.165 0.027
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.027
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.027
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.027
MAPK15 N/A 0.165 0.027
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.027
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.165 0.027
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.027
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.165 0.027
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.027
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.165 0.027
CNN2 CNN2: Calponin-2 0.165 0.027
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.027
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.165 0.027
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.165 0.027
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.148 0.027
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.148 0.027
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.148 0.027
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.148 0.027
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.027
CDC2 CDC2: Cell division control protein 2 homolog 0.148 0.027
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.027
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.027
ELMO1 N/A 0.148 0.027
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.027
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.148 0.027
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.148 0.027
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.027
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.027
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.027
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.148 0.027
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.148 0.027
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.148 0.027
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.027
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.148 0.027
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.148 0.027
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.148 0.027
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.027
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.027
ARHGEF7 N/A 0.148 0.027
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.148 0.027
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.027
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.027
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.027
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.027
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.027
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.148 0.027
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.148 0.027
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.027
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.148 0.027
TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 0.145 0.251
RET urf-ret: Urf-ret protein 0.145 0.200
AMHR2 AMHR2, AMHR: Anti-Muellerian hormone type-2 receptor precursor 0.143 0.162
STYK1 STYK1, NOK: Tyrosine protein-kinase STYK1 0.143 0.251
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.136 0.041
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.128 0.251
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.123 0.0308
GAB1 GAB1: GRB2-associated-binding protein 1 0.123 0.0308
INSRR INSRR, IRR: Insulin receptor-related protein precursor 0.115 0.162
MUSK MUSK: Muscle, skeletal receptor tyrosine protein kinase precursor 0.115 0.162
ROR2 ROR2, NTRKR2: Tyrosine-protein kinase transmembrane receptor ROR2 precursor 0.115 0.200
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.110 0.0308
RDX RDX: Radixin 0.110 0.0308
PLD2 PLD2: Phospholipase D2 0.110 0.0308
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.110 0.0308
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.110 0.0308
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.110 0.0308
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.0308
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.099 0.0308
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.099 0.0308
SPTAN1 N/A 0.098 0.0308
CNN3 CNN3: Calponin-3 0.098 0.0308
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.0308
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.097 0.0308
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.097 0.067
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.0308
SORBS3 SORBS3, SCAM1: Vinexin 0.097 0.0308
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.088 0.0308
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.088 0.0308
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.088 0.041
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.088 0.0308
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.088 0.0308
CTTN CTTN, EMS1: Src substrate cortactin 0.088 0.041
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.081 0.032
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.065 0.032
GRK7 GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor 0.056 0.027
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.056 0.027
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.027
SH3GLB1 SH3GLB1, CGI-61: SH3 domain GRB2-like protein B1 0.041 0.0308
CDC2L6 CDC2L6, CDK11, KIAA1028: Cell division cycle 2-like protein kinase 6 0.036 0.0308
CSNK1A1 CSNK1A1: Casein kinase I isoform alpha 0.036 0.0308
KRIT1 KRIT1, CCM1: Krev interaction trapped protein 1 0.036 0.0308
MTMR6 MTMR6: Myotubularin-related protein 6 0.036 0.0308
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.036 0.0308
CSNK1G3 CSNK1G3: Casein kinase I isoform gamma-3 0.0308 0.0308
ROS1 ROS1: Proto-oncogene tyrosine-protein kinase ROS precursor 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
NULL N/A 0.0288 0.0288
AATK apoptosis-associated tyrosine kinase 0.0288 0.0288
TESK2 TESK2: Dual specificity testis-specific protein kinase 2 0.0288 0.0288
NULL Tyrosine kinase 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
DDR2 DDR2, NTRKR3, TKT, TYRO10: Discoidin domain-containing receptor 2 precursor 0.0288 0.0288
TTN TTN: Uncharacterized protein TTN (Fragment) 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
NTRK3 NTRK3, TRKC: NT-3 growth factor receptor precursor 0.0288 0.0288
NULL N/A 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
MUSK MUSK: MUSK protein 0.0288 0.0288
NTRK3 N/A 0.0288 0.0288
MAP4K5 MAP4K5: Mitogen-activated protein kinase kinase kinase kinase 5 0.028 0.041
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
RIPK5 RIPK5, KIAA0472, HDCMD38P, RIP5, SGK496: Receptor-interacting serine/threonine-p 0.027 0.027
ABI3 ABI3, NESH: ABI gene family member 3 0.027 0.027
NEK4 NEK4, STK2: Serine/threonine-protein kinase Nek4 0.027 0.027
CASKIN1 N/A 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
CDC2L2 N/A 0.027 0.027
NEBL N/A 0.027 0.027
STAC STAC: SH3 and cysteine-rich domain-containing protein 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
PXK PXK: PX domain-containing protein kinase-like protein 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
PTPN13 N/A 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
MID2 N/A 0.027 0.027
PSD3 N/A 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
FANK1 FANK1, HSD13, UNQ6504/PRO21382: Fibronectin type 3 and ankyrin repeat domains pr 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
SHANK1 SHANK1: SH3 and multiple ankyrin repeat domains protein 1 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
ALS2CR7 ALS2CR7: Serine/threonine-protein kinase ALS2CR7 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
ASB2 ASB2: Ankyrin repeat and SOCS box protein 2 0.027 0.027
SORBS2 N/A 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
CAMKK1 CAMKK1, CAMKKA: Calcium/calmodulin-dependent protein kinase kinase 1 0.027 0.027
ANKK1 ANKK1, PKK2, SGK288: Ankyrin repeat and protein kinase domain-containing protein 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
UBL7 UBL7, BMSCUBP, SB132: Ubiquitin-like protein 7 0.027 0.027
PPP1R9A PPP1R9A, KIAA1222: Neurabin-1 0.027 0.027
TRIM9 TRIM9, KIAA0282, RNF91: Tripartite motif-containing protein 9 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
PDIK1L PDIK1L, CLIK1L: Serine/threonine-protein kinase PDIK1L 0.027 0.027
EFS EFS: Embryonal Fyn-associated substrate 0.027 0.027
NEK11 NEK11: Serine/threonine-protein kinase Nek11 0.027 0.027
STK35 STK35, CLIK1, PDIK1: Serine/threonine-protein kinase 35 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 0.027 0.027
FAM43A N/A 0.027 0.027
OSBPL9 N/A 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
FES N/A 0.0258 0.0288
0.572
Total Score 3.62